最新医学別冊　診断と治療のABC135　喘息

出版社： 最新医学社
発行日： 2018-06-01
分野： 臨床医学：一般  >  雑誌
ISSN： 03708241
雑誌名：
特集： 喘息
電子書籍版： 2018-06-01
書籍・雑誌
≪全国送料無料でお届け≫
品切れ

5,500 円(税込)

電子書籍
章別単位での購入はできません
ブラウザ、アプリ閲覧

2,750 円(税込)

購入する

目次

  • 特集　喘息

    序論
    眼で見る喘息

    第１章　概念・定義と疫学
    　概念・定義
    　疫学

    第２章　病理・病態生理
    　遺伝的要因
    　環境因子
    　感染症の関与
    　病態生理
    　病理

    第３章　診断
    　病歴、聴診、身体所見
    　生理学的検査
    　気道炎症の評価
    　画像所見
    　COPDとの鑑別・合併
    　診断と鑑別診断

    第４章　管理・治療
    　喘息予防・管理ガイドライン
    　薬物による長期管理
    　増悪の治療
    　アレルギー学的評価と原因療法
    　抗IgE抗体療法 高槻赤十字病院
    　その他の生物学的製剤を含む最新の薬物治療
    　気管支サーモプラスティ
    　患者教育指導、病薬連携
    　医療経済的考察

    第５章　特殊病態・併存症
    　難治性喘息の病態・フェノタイプ、バイオマーカー
    　慢性咳嗽・咳喘息
    　高齢者喘息
    　好酸球性副鼻腔炎・アレルギー性鼻炎
    　　１．内科の立場から
    　　２．耳鼻咽喉科の立場から

    コラム
    　喘息とSmall airway
    　喫煙と喘息
    　喘息におけるLAMAの位置付け

この書籍の参考文献

参考文献のリンクは、リンク先の都合等により正しく表示されない場合がありますので、あらかじめご了承下さい。

本参考文献は電子書籍掲載内容を元にしております。

第1章 概念・定義と疫学

P.24 掲載の参考文献
1) Barnes P J : Asthma. In Harrison's principles of internal medicine 19th Ed. McGraw-Hill Education, P 1669-1681, 2015.
 
2) 大田健監 : GINA2006 日本語版. 協和企画, 東京, 2007.
 
3) Bentley A M, et al : Identification of T lymphocytes, macrophages, and activated eosinophils in the bronchial mucosa in intrinsic asthma. Relationship to symptoms and bronchial responsiveness. Am Rev Respir Dis 146 : 500-506, 1992.
PubMed
4) 「喘息予防・管理ガイドライン 2015」作成委員会 : 喘息予防・管理ガイドライン 2015. 共和企画, 東京, 2015.
 
5) Brusselle G et al : Targeting immune pathways for therapy in asthma and chronic obstructive pulmonary disease. Ann Am Thorac Soc 11 (Suppl 5) : S322-328, 2014.
 
6) Cockcroft DW : Airway responsiveness. In : Asthma (Barnes P J, et al, eds) p1253-p1266. Lippincott-Raven Publishers, Philadelphia, 1997.
 
7) 一ノ瀬正和 : 気道内径調節のメカニズム. 臨床呼吸機能検査 第8版 (日本呼吸器学会肺生理専門委員会編). メディカルレビュー社, 東京, 2016.
 
8) Haldar P, et al : Cluster analysis and clinical asthma phenotypes. Am J Respir Crit Care Med 178 : 218-224, 2008.
PubMed
P.32 掲載の参考文献
1) 厚生労働省 : 平成15年保健福祉動向調査 アレルギー様症状. <http://www.mhlw.go.jp/toukei/saikin/hw/hftyosa/hftyosaO3/>
 
2) 厚生労働省 : 第3章 気管支喘息 (2. 成人喘息の疫学, 診断, 治療と保健指導, 患者教育). <http://www.mhlw.go.jp/new-info/kobetu/kenkou/ryumachi/dl/jouhou01-07.pdf>
 
3) 喘息予防・管理ガイドライン 2015作成委員会 : 喘息予防・管理ガイドライン 2015. 協和企画, 東京, 2015.
 
4) 日本小児アレルギー学会 : 小児気管支喘息治療・管理ガイドライン 2017. 協和企画, 東京, 2017.
 
5) 厚生労働省 : 平成26年患者調査 (傷病分類編 <http://www.mhlw.go.jp/toukei/saikin/hw/kanja/10syoubyo/>
 
6) 厚生労働省 : 第3章 気管支喘息 (1. 小児喘息の疫学, 診断治療と保健指導, 患者教育). <http://www.mhlw.go.jp/new-info/kobetu/kenkou/ryumachi/d1/jouhou01-06.pdf>
 
7) 日本小児アレルギー学会 : 小児気管支喘息 治療・管理ガイドライン 2017 Web版. <http://www.jspaci.jp/modules/journal/index.php?content_id=13>
 
8) McGeachie M J, et al : Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma. N Engl J Med 374 (19) : 1842-1852, 2016.
 
9) Nakazawa T, et al : Current asthma deaths among adults in Japan. Allergol Int 53 : 205-209, 2004.
 

第2章 病理・病態生理

P.39 掲載の参考文献
1) Holloway J W, et al : Genetics of allergic disease. J Allergy Clin Immunol 125 (suppl 2) : S81-94, 2010.
 
2) Moff att M F, et al : Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 448 : 470-473, 2007.
 
3) Moff att M F, et al : A large-scale, consortium-based genomewide association study of asthma. N Engl J Med 363 : 1211-1221, 2010.
 
4) Torgerson D G, et al : Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet 43 : 887-892, 2011.
PubMed
5) Liu Y P, et al : Association of ORMDL3 with rhinovirus-induced endoplasmic reticulum stress and type I Interferon responses in human leucocytes. Clin Exp Allergy 47 (3) : 371-382, 2017.
PubMed
6) Gudbjartsson D F, et al : Sequence variants aff ecting eosinophil numbers associate with asthma and myocardial infarction. Nat Genet 41 : 342-347, 2009.
 
7) Li X, et al : Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions. J Allergy Clin Immunol 125 : 328-335, e11, 2010.
 
8) Noguchi E, et al : Genome-wide association study identifi es HLA-DP as a susceptibility gene for pediatric asthma in Asian populations. PLoS Genet 7 : e1002170, 2011,
 
9) Hirota T, et al : Genome-wide association study identifi es three new susceptibility loci for adult asthma in the Japanese population. Nat Genet 43 : 893-896, 2011.
 
10) Bonnelykke K, et al : A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations. Nat Genet 46 : 51-55, 2014.
PubMed
11) Jamieson K C, et al : Rhinovirus in the Pathogenesis and Clinical Course of Asthma. Chest 148 (6) : 1508-1516, 2015.
PubMed
12) Cox D W, et al : Human rhinovirus species C infection in young children with acute wheeze is associated with increased acute respiratory hospital admissions. Am J Respir Crit Care Med 188 : 1358-1364, 2013.
PubMed
13) Bizzintino J, et al : Association between human rhinovirus C and severity of acute asthma in children. Eur Respir J 37 : 1037-1042, 2011.
PubMed
14) Miller E K, et al : Human rhinovirus C associated with wheezing in hospitalised children in the Middle East. J Clin Virol 46 : 85-89, 2009.
 
15) Bochkov Y A, et al : Cadherin-related family member 3, a childhood asthma susceptibility gene product, mediates rhinovirus C binding and replication. Proc Nad Acad Sci U S A 112 : 5485-5490, 2015.
 
16) Kanazawa J, et al : Genetic association of the functional CDHR3 genotype with early-onset adult asthma in Japanese populations. Allergol Int 66 : 563-567, 2017.
PubMed
17) Yatagai Y, et al : Variants near the HLA complex group 22 gene (HCG22) confer increased susceptibility to lateonset asthma in Japanese populations. J Allergy Clin Immunol 138 (1) : 281-283, 2016.
PubMed
18) Yatagai Y, et al : Genomewide association study identifies HAS2 as a novel susceptibility gene for adult asthma in a Japanese population. Clin Exp Allergy 44 (11) : 1327-1334, 2014.
 
19) Strachan D P : Hay fever, hygiene, and household size. BMJ 299 : 1259-1260, 1989.
PubMed
20) Kauffmann F, et al : Gene-environment interactions in asthma and allergic diseases : challenges and perspectives. J Allergy Clin Immunol 130 : 1229-1240, quiz 1241-1242, 2012.
 
21) Sigurs N, et al : Respiratory syncytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7. Am J Respir Crit Care Med 161 : 1501-1507, 2000.
PubMed
22) Stein R T, et al : Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years. Lancet 354 : 541-545, 1999.
PubMed
23) Kotaniemi-Syrjanen A, et al : Rhinovirus-induced wheezing in infancy : the first sign of childhood asthma? J Allergy Clin Immunol 111 : 66-71, 2003.
PubMed
24) Jackson D J, et al : Wheezing rhinovirus illnesses in early life predict asthma development in high-risk children. Am J Respir Crit Care Med 178 : 667-672, 2008.
PubMed
25) Bonnelykke K, et al : Association between respiratory infections in early life and later asthma is independent of virus type. J Allergy Clin Immunol 136 : 81-86, e84, 2015.
 
26) Caliskan M, et al : Rhinovirus wheezing illness and genetic risk of childhood-onset asthma. N Engl J Med 368 : 1398-1407, 2013.
PubMed
27) Simpson A, et al : Endotoxin exposure, CD14, and allergic disease : an interaction between genes and the environment. Am J Respir Crit Care Med 174 : 386-392, 2006.
PubMed
28) Smit L A, et al : Atopy and new-onset asthma in young Danish farmers and CD14, TLR2, and TLR4 genetic polymorphisms : a nested case-control study. Clin Exp Allergy 37 : 1602-1608, 2007.
PubMed
29) Smit L A, et al : CD14 and toll-like receptor gene polymorphisms, country living, and asthma in adults. Am J Respir Crit Care Med 179 : 363-368, 2009.
PubMed
30) Bottema R W, et al : Interleukin 13, CD14, pet and tobacco smoke influence atopy in three Dutch cohorts : the allergenic study. Eur Respir J 32 : 593-602, 2008.
PubMed
31) Leynaert B, et al : Association between farm exposure and atopy, according to the CD14 C-159T polymorphism. J Allergy Clin Immunol 118 : 658-665, 2006.
 
32) Gern J E, et al : Effects of dog ownership and genotype on immune development and atopy in infancy. J Allergy Clin Immunol 113 : 307-314, 2004.
PubMed
33) Eder W, et al : Opposite effects of CD 14/-260 on serum IgE levels in children raised in different environments. J Allergy Clin Immunol 116 : 601-607, 2005.
PubMed
34) Israel E, et al : Use of regularly scheduled albuterol treatment in asthma : genotype-stratified, randomised, placebo-controlled cross-over trial. Lancet 364 (9444) : 1505-1512, 2004.
PubMed
35) Hancox R J, et al : Polymorphism of the 2-adrenoceptor and the response to long-term 2-agonist therapy inasthma. Eur Respir J 11 : 589-593, 1998.
 
36) Taylor D R, et al : Asthma exacerbations during long term β agonist use : influence of β2 adrenoceptor polymorphism. Thorax 55 : 762-767, 2000.
 
37) Tantisira K G, et al : Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N Engl J Med 365 : 1173-1183, 2011.
PubMed
P.47 掲載の参考文献
1) Ahluwalia S K et al : Indoor Environmental Interventions for Furry Pet Allergens, Pest Allergens, and Mold : Looking to the Future. J Allergy Clin Immunol Pract 6 (1) : 9-19, 2018.
 
2) Thomas W R : Hierarchy and molecular properties of house dust mite allergens. Allergol Int 64 (4) : 304-311, 2015.
PubMed
3) Trompette A, et al : Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 457 (7229) : 585-588, 2009.
PubMed
4) Lau J Y, et al : Bed Encasings Reduce Reservoir Allergens but not Aeroallergens. J Allergy Clin Immunol 117 (2) : S30, 2006.
 
5) Tovey E R, et al : Time-Based Measurement of Personal Mite Allergen Bioaerosol Exposure over 24 Hour Periods. PLoS One 11 (5) : e0153414, 2016.
PubMed
6) Gotzsche P C, et al : House dust mite control measures for asthma : systematic review. Allergy 63 (6) : 646-659, 2008.
PubMed
7) Nishioka K, et al : Preventive effect of bedding encasement with microfine fibers on mite sensitization. J Allergy Clin Immunol 101 (1 Pt 1) : 28-32, 1998.
 
8) Marks G B, et al : Prevention of asthma during the first 5 years of life : a randomized controlled trial. J Allergy Clin Immunol 118 (1) : 53-61, 2006.
PubMed
9) Shirai T, et al : Effect of pet removal on pet allergic asthma. Chest 127 (5) : 1565-1571, 2005.
PubMed
10) Twaroch T E, et al : Mold allergens in respiratory allergy : from structure to therapy. Allergy Asthma Immunol Res 7 (3) : 205-220, 2015.
PubMed
11) Masaki K, et al : Characteristics of severe asthma with fungal sensitization. Ann Allergy Asthma Immunol 119 (3) : 253-257, 2017.
PubMed
12) Pongracic J A, et al : Differential effects of outdoor versus indoor fungal spores on asthma morbidity in inner-city children. J Allergy Clin Immunol 125 (3) : 593-599, 2010.
 
13) Tham R, et al : Associations between outdoor fungal spores and childhood and adolescent asthma hospitalizations. J Allergy Clin Immunol 139 (4) : 1140-1147, e1144, 2017.
 
14) Zhang Z, et al : beta-Glucan exacerbates allergic asthma independent of fungal sensitization and promotes steroid-resistant TH2/TH17 responses. J Allergy Clin Immunol 139 (1) : 54-65, e58, 2017.
 
15) Chew G L, et al : Procedures to Assist Health Care Providers to Determine When Home Assessments for Potential Mold Exposure Are Warranted. J Allergy Clin Immunol Pract 4 (3) : 417-422. e412, 2016.
 
16) Sauni R, et al : Remediating buildings damaged by dampness and mould for preventing or reducing respiratory tract symptoms, infections and asthma (Review). Evid Based Child Health 8 (3) : 944-1000, 2013.
 
17) Khreis H, et al : Traffic-Related Air Pollution and Childhood Asthma : Recent Advances and Remaining Gaps in the Exposure Assessment Methods. Int J Environ Res Public Health 14 (3) : pii : E312, 2017.
 
18) Orellano P, et al : Effect of outdoor air pollution on asthma exacerbations in children and adults : Systematic review and multilevel meta-analysis. PLoS One 12 (3) : e0174050, 2017.
PubMed
19) Bromberg P A : Mechanisms of the acute effects of inhaled ozone in humans. Biochim Biophys Acta 1860 (12) : 2771-2781, 2016.
PubMed
20) McCreanor J, et al : Respiratory Effects of Exposure to Diesel Trafiic in Persons with Asthma. N Engl J Med 357 (23) : 2348-2358, 2007.
PubMed
21) Carlsten C, et al : Diesel exhaust augments allergen-induced lower airway inflammation in allergic individuals : a controlled human exposure study. Thorax 71 (1) : 35-44, 2016.
PubMed
22) Brandt E B, et al : Diesel exhaust particle induction of IL-17A contributes to severe asthma. J Allergy Clin Immunol 132 (5) : 1194-1204, e1192, 2013.
 
23) Kuroda E, et al : Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin-1alpha Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation. Immunity 45 (6) : 1299-1310, 2016.
PubMed
24) Brandt E B, et al : Exposure to allergen and diesel exhaust particles potentiates secondary allergen-specific memory responses, promoting asthma susceptibility. J Allergy Clin Immunol 136 (2) : 295-303, e297, 2015.
 
25) Robinson R K, et al : Mechanistic link between diesel exhaust particles and respiratory reflexes. J Allergy Clin Immunol 2017. [Epub ahead of print]
 
P.55 掲載の参考文献
1) Fraczek M G, et al : Corticosteroid treatment is associated with increased filamentous fungal burden in allergic fungal disease. J Allergy Clin Immunol 2018 (in press).
 
2) Contoii M, et al : Role of deficient type III interferon-lambda production in asthma exacerbations. Nat Med 12 : 1023-1026, 2006.
 
3) Simpson J L, et al : Reduced Antiviral Interferon Production in Poorly Controlled Asthma Is Associated With Neutrophilic Inflammation and High-Dose Inhaled Corticosteroids. Chest 149 : 704-713, 2016.
PubMed
4) Fukahori S, et al : Clearance of Aspergillus fumigatus is impaired in the airway in allergic inflammation. Ann Allergy Asthma Immunol 113 : 180-186, 2014.
PubMed
5) Fitzpatrick A M, et al : Alveolar macrophage phagocytosis is impaired in children with poorly controlled asthma. J Allergy Clin Immunol 121 : 1372-1378, 2008.
PubMed
6) Mehta A K, et al : Rhinovirus infection interferes with induction of tolerance to aeroantigens through OX40 ligand, thymic stromal lymphopoietin, and IL-33. J Allergy Clin Immunol 137 : 278-288, 2016.
PubMed
7) Saravia J, et al : Respiratory Syncytial Virus Disease Is Mediated by Age-Variable IL-33. PLoS Pathog 11 : e1005217, 2015.
PubMed
8) Albacker L A, et al : Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity. Nat Med 19 : 1297-1304, 2013.
 
9) Arrieta M C, et al : Associations between infant fungal and bacterial dysbiosis and childhood atopic wheeze in a nonindustrialized setting. J Allergy Clin Immunol 2018 (in press).
 
10) Yoshii Y, et al : Detection of pathogens by real-time PCR in adult patients with acute exacerbation of bronchial asthma. BMC Pulm Med 17 : 150, 2017.
PubMed
11) Behera A K, et al : Blocking intercellular adhesion molecule-1 on human epithelial cells decreases respiratory syncytial virus infection. Biochem Biophys Res Commun 280 : 188-195, 2001.
PubMed
12) Esquivel A, et al : Effects of Omalizumab on Rhinovirtls Infections, Illnesses, and Exacerbations of Asthma. Am J Respir Crit Care Med 196 : 985-992, 2017.
PubMed
13) Matsuse H, et al : Effects of a short course of pranlukast combined with systemic corticosteroid on acute asthma exacerbation induced by upper respiratory tract infection. J Asthma 49 : 637-641, 2012.
 
14) Matsuse H, et al : Retrospective cohort study of leukotriene receptor antagonist therapy for preventing upper respiratory infection-induced acute asthma exacerbations. Allergy Rhinol (Providence) 4 : e127-131, 2013.
PubMed
15) Alam R, et al : Airway and serum biochemical correlates of refractory neutrophilic asthma. J Allergy Clin Immunol 140 : 1004-1014, 2017.
PubMed
16) Tang F S, et al : Differential neutrophil activation in viral infections : Enhanced TLR-7/8-mediated CXCL8 release in asthma. Respirology 21 : 172-179, 2016.
PubMed
17) Woolnough K F, et al : The relationship between biomarkers of fungal allergy and lung damage in asthma. Clin Exp Allergy 47 : 48-56, 2017,
PubMed
18) Denning D W, et al : The link between fungi and severe asthma : a summary of the evidence. Eur Respir J 27 : 615-626, 2006.
PubMed
19) Castanhinha S, et al : Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33. J Allergy Clin Immunol 136 : 312-322, 2015.
PubMed
20) Huang Y J, et al : Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma. J Allergy Clin Immunol 127 : 372-381, 2011.
PubMed
P.62 掲載の参考文献
1) Asthma, G. I. f., Global Initiative for Asthma : Global strategy for asthma management and prevention 2017. Bethesda, MD, U S A : GINA, 2017. <http://ginasthma.org.>
 
2) Brusselle G, et al : Targeting immune pathways for therapy in asthma and chronic obstructive pulmonary disease. Ann Am Thorac Soc 11 (Suppl 5) : S322-328, 2014.
 
3) Motomura Y, et al : Basophil-derived interleukin-4 controls the function of natural helper cells, amember of ILC2s, in lung inflammation. Immunity 40 (5) : 758-771, 2014.
 
4) Moffatt M F, et al : A large-scale, consortium-based genomewide association study of asthma. N Engl J Med 363 (13) : 1211-1221, 2010.
PubMed
5) Endo Y, et al : The interleukin-33-p38 kinase axis confers memory T helper 2 cell pathogenicity in the airway. Immunity 42 (2) : 294-308, 2015.
PubMed
6) Shinoda K, et al : Thy1+ IL-7+ lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation. Proc Nat Acad Sci USA 113 (20) : E2842-E2851, 2016.
PubMed
7) Hayashi N, et al : T helper 1 cells stimulated with ovalbumin and IL-18 induce airway hyperresponsiveness and lung fibrosis by IFN-gamma and IL-13 production. Proc Natl Acad Sci U S A 104 : 14765-14770, 2007.
PubMed
8) Motomura Y, et al : The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells. Nat Immunol 12 : 450-459, 2011.
PubMed
9) Moro K, et al : Innate production of T (H) 2 cytokines by adipose tissue-associated c-Kit (+) Sca-1 (+) lymphoid cells. Nature 463 (7280) : 540-544, 2010.
 
10) Halim T Y, et al : Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation. Immunity 36 (3) : 451-463, 2012.
PubMed
11) Kabata H, et al : Thymic stromal lymphopoietin induces cordcosteroid resistance in natural helper cells during airway inflammation. Nat Commun 4 : 2675, 2013.
 
12) Liu S, et al : Steroid resistance of airway type 2 innate lymphoid cells from patients with severe asthma : The role of thymic stromal lymphopoietin. J Allergy Clin Immunol 141 (1) : 257-268, e6, 2018.
 
13) Nakagome K, et al : Dopamine D1-like receptor antagonist attenuates Th17-mediated immune response and ovalbumin antigen-induced neutrophlic airway inflammation. J Immunol 186 (10) : 5975-5982, 2011.
 
14) Kudo M, et al : IL-17A produced by alphabeta T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction. Nat Med 18 (4) : 547-554, 2012.
PubMed
15) Al-Ramli W, et al : T (H) 17-associated cytokines (IL-17A and IL-17F) in severe asthma. J Allergy Clin Immunol 123 (5) : 1185-1187, 2009.
 
16) Cosmi L, et al : Identification of a novel subset of human circulating memory CD4 (+) T cells that produce both IL-17A and IL-4. J Allergy Clin Immunol 125 (1) : 222-230, e1-4, 2010.
 
17) Prakash Y S : Airway smooth muscle in airway reactivity and remodeling : what have we learned? Am J physiol Lung Cell Mol Physiol 305 (12) : L912-L933, 2013.
PubMed
18) Bergeron C, et al : Airway remodelling in asthma from benchside to clinical practice. Can Respir J 17 (4) : e85-e93, 2010.
PubMed
19) Sagara H, et al : Activation of TGF-beta/Smad2 signaling is associated with airway remodeling in asthma. J Allergy Clin Immunol 110 (2) : 249-254, 2002.
PubMed
20) Matsumoto H, et al : Relationship of airway wall thickening to an imbalance between matrix metalloproteinase-9 and its inhibitor in asthma. Thorax 60 (4) : 277-281, 2005.
 
21) Grainge C L, et al : Effect of bronchoconstriction on airway remodeling in asthma. N Engl J Med 364 (21) : 2006-2015, 2011.
PubMed
22) Israel E, et al : Severe and Difficult-to-Treat Asthma in Adults. N Engl J Med 377 (10) : 965-976. 2017.
PubMed
23) Bates J H : Physiological Mechanisms of Airway Hyperresponsiveness in Obese Asthma. Am J Respir Cell Mol Biol 54 (5) : 618-623, 2016.
PubMed
24) Wang L, et al : The functional consequences of structural changes in the airways : implications for airway hyperresponsiveness in asthma. Chest 123 (3 Suppl) : 356s-362s, 2003.
 
25) James A L, et al : The mechanics of airway narrowing in asthma. Am Rev Respir Dis 139 (1) : 242-246, 1989.
PubMed
26) Fredberg J J : Airway smooth muscle in asthma. Perturbed equilibria of myosin binding. Am J Respir Crit Care Med 161 (3 Pt 2) : S158-160, 2000.
 
P.72 掲載の参考文献
1) Niimi A, et al : Clinical assessment of airway remodeling in asthma : utility of computed tomography. Clin Rev Allergy Immunol 27 : 45-58, 2004.
PubMed
2) James A L, et al : Clinical relevance of airway remodelling in airway diseases. Eur Respir J 30 : 134-155, 2007.
PubMed
3) Bai A, et al : Proposed nomenclature for quantifying subdivisions of the bronchial wall. J Appl Physiol 77 : 1011-1014, 1994.
 
4) Barnes P J原著, 新実彰男訳 : 喘息. ハリソン内科学 (第5版) 日本語版, p1716-1728. メディカルサイエンスインターナショナル, 東京, 2017.
 
5) Papi A, et al : Asthma. Lancet 391 (10122) : 783-800, 2018.
PubMed
6) Lipworth B, et al : Unlocking the quiet zone : the small airway asthma phellotype. Lancet Respir Med 2 : 497-506, 2014.
PubMed
7) Niimi A, et al : Eosinophilic inflammation in cough variant asthma. Eur Respir J 11 : 1064-1069, 1998.
PubMed
8) Brightling C E, et al : Mast cell infiltration of airway smooth muscle in asthma. N Engl J Med 346 : 1699-1705, 2002.
PubMed
9) Niimi A, et al : Nature of airway inflammation and remodeling in chronic cough. J Allergy Clin Immunol 116 : 565-570, 2005.
 
10) Niimi A : Structural changes in the airways : Cause or effect of chronic cough? Pulm Pharmacol Ther 24 : 328-333, 2011.
PubMed
11) Hastie A T, et al : Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes. J Allergy Clin Immunol 125 : 1028-1036, 2010.
PubMed
12) Matsuoka H, et al : Inflammatory subtypes in cough-variant asthma : association with maintenance doses of inhaled corticosteroids. Chest 138 : 1418-1425, 2010.
PubMed
13) Tschumperlin D J, et al : Mechanical stress triggers selective release of fibrotic mediators from bronchial epithelium. Am J Respir Cell Mol Biol 28 : 142-149, 2003.
PubMed
14) Grainge C L, et al : Effect of bronchoconstriction on airway remodeling in asthma. N Engl J Med 364 : 2006-2015, 2011.
PubMed
15) Nakaji H, et al : Airway remodeling associated with cough hypersensitivity as a consequence of persistent cough : An experimental study. Respir Invest 54 : 419-427, 2016.
 
16) Fehrenbach H, et al : Airway remodeling in asthma what really matters. Cell Tissue Res 367 : 551-569, 2017.
PubMed
17) O'Connell F, et al : Abnormal intraepithelial airway nerves in persistent unexplained cough? Am J Respir Crit Care Med 152 : 2068-2075, 1995.
PubMed
18) Lee S Y, et al : Substance P-immunoreactive nerves in endobronchial biopsies in cough-variant asthma and classic asthma. Respiration 70 : 49-53, 2003.
PubMed
19) Groneberg D A, et al : Increased expression of TRPV-1 in airway nerves of chronic cough. Am J Respir Crit Care Med 170 : 1276-1280, 2004.
PubMed
20) Mitchell J E, et al : Expression and characterization of the intracellular vanilloid receptor in bronchi from patients with chronic cough. Exp Lung Res 31 : 295-306, 2005.
PubMed
21) Ollerenshaw S J, et al : Substance P immunoreactive nerves in airways from asthmatics and nonasthmatics. Eur Respir J 4 : 673-682, 1991.
PubMed
22) McGarvey L P, et al : Increased expression of bronchial epithelial TRPV1 channels in patients with severe asthma. J Allergy Clin Immunol 133 : 704-712, e4, 2014.
 
23) Howarth P H, et al : Neuropeptide-containing nerves in endobronchial biopsies from asthmatic and nonasthmatic subjects. Am J Respir Cell Mol Biol 13 : 288-296, 1995.
PubMed
24) James A L, et al : The mechanics of airway narrowing in asthma. Am Rev Respir Dis 139 : 242-246, 1989.
PubMed
25) Berair R, et al : Asthma therapy and its effect on airway remodelling. Drugs 74 : 1345-1369, 2014.
PubMed
26) Lambert R K, et al : Functional significance of increased airway smooth muscle in asthma and COPD. J Appl Physiol 74 : 2771-2781, 1993.
PubMed
27) Benayoun L, et al : Airway structure alterations selectively associated with severe asthma. Am J Respir Crit Care Med 167 : 1360-1368, 2003.
PubMed
28) Berair R, et al : Associations in asthma between quantitative CT and bronchial biopsy-derived airway remodeling. Eur Respir J 49 : 1601507, 2017.
 
29) Milanese M, et al : On the functional consequences of bronchial basement membrane thickening. J Appl Physiol 91 : 1035-1040, 2001.
PubMed
30) Niimi A, et al : Relation of airway wall thickness to airway sensitivity and airway reactivity in asthma. Am J Respir Crit Care Med 168 : 983-988, 2003.
PubMed
31) Bai T R, et al : The effect of age and duration of disease on airway structure in fatal asthma. Am J Respir Crit Care Med 162 : 663-669, 2000.
PubMed
32) Kuyper L M, et al : Characterization of airway plugging in fatal asthma. Am J Med 115 : 6-11, 2003.
PubMed
33) Jinnai M, et al : Induced sputum concentrations of mucin in patients with asthma and chronic cough. Chest 137 : 1122-1129, 2010.
PubMed
34) Haraguchi M, et al : Morphometric analysis of bronchial cartilage in chronic obstructive pulmonary disease and bronchial asthma. Am J Respir Crit Care Med 159 : 1005-1013, 1999.
PubMed
35) Haley K J : Inflammatory cell distribution within and along asthmatic airways. Am J Respir Crit Care Med 158 : 565-572, 1998.
PubMed
36) Mauad T, et al : Abnormal alveolar attachments with decreased elastic fiber content in distal lung in fatal asthma. Am J Respir Crit Care Med 170 : 857-862, 2004.
PubMed
37) Kraft M, et al : Alveolar tissue inflammation in asthma. Am J Respir Crit Care Med 154 : 1505-1510, 1996.
PubMed
38) Wenzei S E, et al : Asthmatic granulomatosis : a novel disease with asthmatic and granulomatous features. Am J Respir Crit Care Med 186 : 501-507, 2012.
 
P.76 掲載の参考文献
1) Nagasaki T, et al : Allergol Int 62 : 171, 2013.
PubMed
2) Nagasaki T, et al : Ciin Exp Allergy 43 : 608, 2013.
 

第3章 診断

P.83 掲載の参考文献
1) 日本アレルギー学会喘息ガイドライン専門部会監 : 喘息予防・管理ガイドライン 2015. 協和企画, 東京, 2015.
 
2) 野村佳世, 他 : 百日咳と考えられた20例の検討とくにC. pneumoniaeとの重複感染について. 感染症誌 84 (臨増) : 296, 2010.
 
3) 中野直子, 他 : 気管支喘息患者におけるペット飼育の実態と対策. 小児科 41 : 765-769, 2000.
 
4) Demeter S L, et al : Hyperventilation syndrome and asthma. Am J Med 81 (6) : 989-994, 1986.
PubMed
5) Yanagisawa S, et al : Definition and diagnosis of asthma-COPD overlap (ACO). Allergol Int 2018 [Epub ahead of print]
 
6) Nagasaka Y : Lung sounds in bronchial asthma. Allergol Int 61 (3) : 353-363, 2012.
PubMed
7) 工藤翔二 : 肺聴診の歴史散歩. 聴いて見て考える肺の聴診 (工藤翔二). p1-4, アトムス, 東京, 2014.
 
8) Shimoda T, et al : Prediction of airway inflammation in patients with asymptomatic asthma by using lung sound analysis. J Allergy Clin Immunol Pract 2 (6) : 727-732, 2014.
PubMed
9) Shimoda T, et al : Lung Sound Analysis and Airway Inflammation in Bronchial Asthma. J Allergy Clin Immunol Pract 4 (3) : 505-511, 2016.
PubMed
10) Shimoda T, et al : Lung Sound Analysis Is Useful for Monitoring Therapy in Patients With Bronchial Asthma. J Investig Allergol Clin Immunol 27 (4) : 246-251, 2017.
PubMed
P.95 掲載の参考文献
1) 日本アレルギー学会喘息ガイドライン専門部会監修 : 喘息予防・管理ガイドライン 2015. 協和企画, 東京, 2015.
 
2) 日本呼吸器学会肺生理専門委員会 : 臨床呼吸機能検査 第7版. メディカルレビュー社, 大阪, 2008.
 
3) 杉山公美弥, 他 : 気管支喘息の早期診断基準の提言, アレルギー 57 : 1275-1283, 2008.
Medical*Online
4) Miller M R, et al : ATS/ERS Task Force. Standardisation of spirometry. Eur Respir J 26 : 319-338, 2005.
PubMed
5) Albert P, et al : Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease. Thorax 67 : 701-708, 2012.
PubMed
6) Marotta A, et al : Impulse oscillometry provides an effective measure of lung dysfunction in 4-year-old children at risk for persistent asthma. J Allergy Clin Immunol 112 : 317-322, 2003.
PubMed
7) Cockcroft D W, et al : Direct and indirect challenges in the clinical assessment of asthma. Ann Allergy Asthma Immunol 103 : 363-370, 2009.
 
8) 新実彰男 : 気道過敏性検査. 日胸 71 (増刊号) : S27-S33, 2012.
 
9) Takishima T, et al : Direct-writing recorder of the dose-response curves of the airway to methacholine. Chest 80 : 600-606, 1981.
PubMed
10) Niimi A, et al : Relationship of airway wall thickness to airway senshivity and airway reactivity in asthma. Am J Respir Crit Care Med 168 : 983-988, 2003.
PubMed
11) Smith H J, et al : Forced oscillation technique and impulse oscillometry. Lung Function Testing. Eur Respir Mon 31 : 72-105, 2005.
 
12) Shirai T, et al : Clinical Application of the Forced Oscillation Technique. Intern Med 55 : 559-566, 2016.
PubMed
13) 平井豊博 : Impulse Oscillometry System. 臨病理レビュー 151 : 77-85, 2014.
 
14) Cavalcanti J V, et al : Detection of changes in respiratory mechanics due to increasing degrees of airway obstruction in asthma by the forced oscillation technique. Respir Med 100 : 2207-2219, 2006.
PubMed
15) Jinnai M, et al : Induced sputum concentrations of mucin in patients with asthma and chronic cough. Chest 137 : 1122-1129, 2010.
PubMed
16) Takeda T, et al : Relationship between small airway function and health status, dyspnea and disease control in asthma. Respiration 80 : 120-126, 2010.
PubMed
17) Matsumoto H, et al : Association of alveolar nitric oxide levels with pulmonary function and its reversibility in stable asthma. Respiration 81 : 311-317, 2011.
PubMed
18) Nakaji H, et al : Effects of 24-week add-on treatment with ciclesonide and montelukast on small airways inflammation in asthma. Ann Allergy Asthma Immunol 110 : 198-203. e3, 2013.
 
19) Shi Y, et al : Relating small airways to asthma control by using impulse oscillometry in children. J Allergy Clin Immunol 129 : 671-678, 2012.
 
P.109 掲載の参考文献
1) 日本アレルギー学会 : 喘息予防・管理ガイドライ ン 2015. 協和企画, 東京, 2015.
 
2) Moore W C, et al : Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis. J Allergy Clin Immunol 133 (6) : 1557-1563e5, 2014.
PubMed
3) 斎藤純平 : 気管支喘息における一酸化窒素と硫化水素測定の意義. 臨免疫・アレルギー科 64 : 474-481, 2015.
 
4) Dweik R A, et al : An official ATS clinical practice guideline : interpretation of exhaled nitric oxide levels (FENO) for clinical applications. Am J Respir Crit Care Med 184 (5) : 602-615, 2011.
PubMed
5) Saito J, et al : Differences of fractional exhaled nitric oxide (FeNO) levels performed using two different analyzers. Nihon Kokyuki Gakkai Zasshi 48 (1) : 17-22, 2010.
PubMed
6) Matsunaga K, et al : Reference ranges for exhaled nitric oxide fraction in healthy Japanese adult population. Allergol Int 59 (4) : 363-367, 2010.
PubMed
7) Matsunaga K, et al : Exhaled nitric oxide cutoff values for asthma diagnosis according to rhinitis and smoking status in Japanese subjects. Allergol Int 60 (3) : 331-337, 2011.
PubMed
8) Pin I, et al : Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax 47 (1) : 25-29, 1992.
PubMed
9) Louis R, et al : The relationship between airways inflammation and asthma severity. Am J Respir Crit Care Med 161 (1) : 9-16, 2000.
PubMed
10) McGrath K W, et al : A large subgroup of mild-to-moderate asthma is persistently noneosinophilic. Am J Respir Crit Care Med 185 (6) : 612-619, 2012.
PubMed
11) James A J, et al : Increased YKL-40 and Chitotriosidase in Asthma and Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med 193 (2) : 131-142, 2016.
PubMed
12) Hinks T S, et al : Multidimensional endotyping in patients with severe asthma reveals inflammatory heterogeneity in matrix metalloproteinases and chitinase 3-like protein 1. J Allergy Clin Immunol 138 (1) : 61-75, 2016.
PubMed
13) Saito J, et al : Sputum hydrogen sulfide as a novel biomarker of obstructive neutrophilic asthma. J Allergy Clin Immunol 131 (1) : 232-234 e1-3, 2013.
 
14) Korevaar D A, et al : Diagnostic accuracy of minimally invasive markers for detection of airway eosinophilia in asthma : a systematic review and meta-analysis. Lancet Respir Med 3 (4) : 290-300, 2015.
PubMed
15) Price D B, et al : Blood eosinophil count and prospective annual asthma disease burden : a UK cohort study. Lancet Respir Med 3 (11) : 849-858, 2015.
PubMed
16) Izuhara K, et al : Periostin in Allergic Inflammation. Allergol Int 63 (2) : 143-151, 2014.
 
17) Jia G, et al : Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients. J Allergy Clin Immunol 130 (3) : 647-654 e10, 2012.
 
18) Kanemitsu Y, et al : Increased periostin associates with greater airflow limitation in patients receiving inhaled corticosteroids. J Allergy Clin Immunol 132 (2) : 305-312 e3, 2013.
 
19) Rufo J C, et al : Volatile organic compounds in asthma diagnosis : a systematic review and meta-analysis. Allergy 71 (2) : 175-188, 2016.
PubMed
20) Fens N, et al : Exhaled breath profiling enables discrimination of chronic obstructive pulmonary disease and asthma. Am J Respir Crit Care Med 180 (11) : 1076-1082, 2009.
PubMed
21) Montuschi P, et al : The electronic nose in respiratory medicine. Respiration 85 (1) : 72-84, 2013.
PubMed
22) Horvath I, et al : Exhaled breath condensate : methodological recommendations and unresolved questions. Eur Respir J 26 (3) : 523-548, 2005.
PubMed
23) Leung T F, et al : Recent advances in asthma biomarker research. Ther Adv Respir Dis 7 (5) : 297-308, 2013.
PubMed
24) Zayasu K, et al : Increased carbon monoxide in exhaled air of asthmatic patients. Am J Respir Crit Care Med 156 (4 Pt 1) : 1140-1143, 1997.
 
P.117 掲載の参考文献
1) King G G, et al : Evaluation of airways in obstructive pulmonary disease using high-resolution computed tomography. Am J Respir Crit Care Med 159 : 992-1004, 1999.
PubMed
2) Little S A, et al : High resolution computed tomographic assessment of airway wall thickness in chronic asthma : reproducibility and relationship with lung function and severity. Thorax 57 : 247-253, 2002.
PubMed
3) Niimi A, et al : Airway wall thickness in asthma assessed by computed tomography. Relation to clinical indices. Am J Respir Crit Care Med 162 : 1518-1523, 2000.
PubMed
4) Oguma T, et al : Longitudinal shape irregularity of airway lumen assessed by CT in patients with bronchial asthma and COPD. Thorax 70 : 719-724, 2015.
PubMed
5) Shimizu K, et al : Comparison of airway remodelling assessed by computed tomography in asthma and COPD. Respir Med 105 (9) : 1275-1283, 2011.
PubMed
6) Van Tho N, et al : A mixed phenotype of airway wall thickening and emphysema is associated with dyspnea and hospitalization for chronic obstructive pulmonary disease. Ann Am Thorac Soc 12 (7) : 988-996, 2015.
PubMed
7) Oguma T, et al : Assessment of Small Airways with Computed Tomography : Mosaic Attenuation or Lung Density? Respiration 89 (6) : 539-549, 2015,
PubMed
8) Miller W T Jr, et al : Expiratory air trapping on thoracic computed tomography. A diagnostic subclassification. Ann Am Thorac Soc 11 (6) : 874-881, 2014.
PubMed
9) Ueda T, et al : Role of small airways in asthma : investigation using high-resolution computed tomography. J Allergy Clin Immunol 118 (5) : 1019-1025, 2006.
PubMed
10) Suzuki T, et al : Clinical, physiological, and radiological features of asthma-chronic obstructive pulmonary disease overlap syndrome. Int J Chron Obstruct Pulmon Dis 10 : 947-954, 2015.
PubMed
11) Kitaguchi Y, et al : Comparison of pulmonary function in patients with COPD, asthma-COPD overlap syndrome, and asthma with airflow limitation. Int J Chron Obstruct Pulmon Dis 11 : 991-997, 2016.
PubMed
12) Kim Y K, et al : Pulmonary involvement in Churg-Strauss syndrome : an analysis of CT, clinical, and pathologic findings. Eur Radiol 17 (12) : 3157-3165, 2007.
PubMed
13) Patterson R, et al : Allergic bronchopulmonary aspergillosis. Natural history and classification of early disease by serologic and roentgenographic studies. Arch Intern Med 146 : 916-918, 1986.
PubMed
14) Franquet T, et al : Spectrum of pulmonary aspergillosis : histologic, clinical, and radiologic findings. Radiographics 21 (4) : 825-837, 2001.
PubMed
15) Lee K S, et al : Relapsing polychondritis : prevalence of expiratory CT airway abnormalities. Radiology 240 (2) : 565-573, 2006.
PubMed
16) Yamashita H, et al : Utility of fluorodeoxyglucose positron emission tomography/computed tomography for early diagnosis and evaluation of disease activity of relapsing polychondritis : a case series and literature review. Rheumatology (Oxford) 53 (8) : 1482-1490, 2014.
PubMed
P.122 掲載の参考文献
1) Tashkin D P, et al : Bronchodilator responsiveness in patients with COPD. Eur Respir J 31 : 742-750, 2008.
PubMed
2) Goleva E et al : Airway remodeling and lack of bronchodilator response in steroid resistant asthma. J Allergy Clin Immunol 120 : 1065-1072, 2007.
PubMed
3) Woodruff P G et al : T-helper type 2-driven inflammation defines major subphenotypes of asthma. Am J Respir Crit Care 180 (5) : 388-395, 2009.
 
4) Brightling C E, et al : Sputum eosinophilia and the short term response to inhaled mometasone in chronic obstructive pulmonary disease. Thorax 60 (3) : 193-198, 2005.
PubMed
5) Zietkowski Z, et al : The influence of inhaled corticosteroids on exhaled nitric oxide in stable chronic obstructive pulmonary disease. Respir Med 99 (7) : 816-824, 2005.
PubMed
6) Pascoe S, et al : Blood eosinophil counts, exacerbations, and response to the addition of inhaled fiuticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease : a secondary analysis of data from two parallel randomised controlled trials. Lancet Respir Med 3 (6) : 435-442, 2015.
 
7) Watz H, et al : Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids : a post-hoc analysis of the WISDOM trial. Lancet Respir Med 4 : 390-398, 2016.
PubMed
8) Peters S P, et al : Predictors of response to tiotropium versus salmeterol in asthmatic adults. J Allergy Clin Immunol 132 (5) : 1068-1074, 2013.
PubMed
9) Gibson P G et al : The overlap syndrome of asthma and COPD : what are its features and how important is it? Thorax 64 : 728-735, 2009.
PubMed
10) Soler-Cataluna J J, et al : Consensus Document on the Overlap Phenotype COPD-Asthma in COPD. Arch Bronconeumol 48 : 331-337, 2012.
PubMed
11) 一般社団法人日本呼吸器学会 : 喘息とCOPDのオーバーラップ 診断と治療の手引き 2018. メディカルレビュー社, 大阪, 2018.
 
P.129 掲載の参考文献
1) 足立満 : 専門医に学ぶ成人と小児のための長引く咳の治療指針. 総合医学社, 東京, 2013.
 
2) 日本呼吸器学会 : 新呼吸器専門医テキスト. 南江堂, 東京, 2015.
 
3) 黨康夫 : 吸入ステロイド薬処方のコツ. アレルギーの臨 36 (6) : 572-575, 2017.
 
4) Global initiative for Asthma, global strategy for asthma management and prevention, updated 2017.
 
5) 一般社団法人日本アレルギー学会 喘息ガイドライン専門部会 : 喘息予防・管理ガイドライン 2015. 協和企画, 東京, 2015.
 
P.131 掲載の参考文献
1) Hamid Q, et al : J Allergy Clin Immunol 100 : 44, 1997.
PubMed
2) Balzar S, et al : Eur Respir J 20 : 254, 2002.
PubMed
3) in't Veen J C, et al : Am J Respir Crit Care Med 160 : 93, 1999.
PubMed
4) Niimi A, et al : Am J Respir Crit Care Med 168 : 988, 2003.
 
5) Ueda T, et al : J Allergy Clin Immunol 118 : 1019, 2006.
PubMed
6) Goldman M D : Pulm Pharmacol Ther 14 : 341, 2001.
PubMed
7) Yamaguchi M, et al : Pulm Pharmacol Ther 22 : 326, 2009.
PubMed

第4章 管理・治療

P.140 掲載の参考文献
1) 「喘息予防・管理ガイドライン 2015」作成委員会 : 喘息予防・管理ガイドライン 2015. 共和企画, 東京, 2015.
 
P.152 掲載の参考文献
1) 一般社団法人日本アレルギー学会. 喘息ガイドラ イン専門部会監 : 喘息予防・管理ガイドライン 2015. 協和企画, 東京, 2015.
 
2) 日本呼吸器学会肺生理専門委員会 : 呼気一酸化窒素 (NO) 測定ハンドブック. 日本呼吸器学会, 東京, 2018.
 
3) Chung K F, et al : International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J 43 : 343-373, 2014.
PubMed
4) Global strategy for asthma management and prevention updated 2017. <www.ginasthma.org>
 
P.164 掲載の参考文献
1) 社団法人日本アレルギー学会 喘息ガイドライン専門部会 : 喘息予防・管理ガイドライン 2015. 協和企画, 東京, 2015.
 
2) Global Initiative for Asthma Global Strategy for Asthma Management and Prevention, 2017. <http://ginasthma.org/>
 
3) Kew K M, et al : Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children. Cochrane Database Syst Rev 7 : CD007524, 2016.
 
4) Reddel H K, et al : Pharmacological strategies for self-management of asthma exacerbations. Eur Respir J 28 : 182-199, 2006.
PubMed
5) 社団法人日本麻酔科学会 : 麻酔薬および麻酔関連薬使用ガイドライン 第3版 第4訂 2017. <http://www.anesth.or.jp/guide/guideline-iyakuhin-index.html>
 
6) 日本呼吸器学会NPPVガイドライン作成委員会編 : NPPV (非侵襲的陽圧換気療法) ガイドライン改訂第2版. 南江堂, 東京, 2015.
 
P.172 掲載の参考文献
1) Guilbert T W, et al : Long-term inhaled corticosteroids in preschool children a high risk for asthma. N Engl J Med 354 : 1985-1997, 2006.
PubMed
2) Takaku Y, et al : Changes in airway inflammation and hyperresponsiveness after inhaled corticosteroid cessation in allergic asthma. Int Arch Allergy Immunol 152 S1 : 41-46, 2010.
 
3) 安枝浩 : ダニアレルゲンの免疫生物学とアレルギー疾患. アレルギー 57 : 807-815, 2008.
Medical*Online
4) Platts-Mills T A E : The role of indoor allergens in chronic allergic disease. J Allergy Clin Immunol 119 : 297-302, 2007.
 
5) Des Roches A, et al : Immunotherapy with a standardized Dermatophagoides pteronyssinus extract VI. Specific immunotherapy prevents the onset of new sensitizations in children. J Allergy Clin Immunol 99 : 450-454, 1997.
 
6) Marogna M, et al : Long-lasting effects of sublingual immunotherapy according to its duration : a 15-year prospective study. J Allergy Clin Immunol 126 : 969-975, 2010.
PubMed
7) O'connor G T : Allergen avoidance in asthma what do we do now? J Allergy Clin Immunol 116 : 26, 2005.
PubMed
8) Murray C S, et al : Preventing Severe Asthma Exacerbations in Children. A Ralldomized Trial of Mite-Impermeable Bedcovers. Am J Respir Crit Care Med 196 : 150-158, 2017.
PubMed
9) Nishioka K, et ai : Preventive effect of bedding encasement with microfine fibers on mite sensitization. J Allergy Clin Immunol 101 : 28-32, 1998.
 
10) Hojo M, et al : The impact of co-existing seasonal allergic rhinitis caused by Japanese Cedar Pollinosis (SAR-JCP) upon asthma control status. Allergol Int 64 : 150-155, 2015.
PubMed
11) 日本アレルギー学会 : スギ花粉症におけるアレルゲン免疫療法の手引き. メディカルレビュー社, 東京, 2013.
 
12) 日本アレルギー学会 : ダニアレルギーにおけるアレルゲン免疫療法の手引き. メディカルレビュー社, 東京, 2015.
 
13) Abramson M J, et al : Is allergen immunotherapy effective in asthma? A meta-analysis of randomized controlled trials. Am J Respir Crit Care Med 151 : 969-974, 1995.
PubMed
14) U. S. Department of Health and Human Services : National Heart, Lung, and Blood Institute. National Asthma Education and Prevention Program. Expert Panel Report 3 (EPR-3) : Guidelines for the Diagnosis and Management of Asthma. 2007.
 
15) Jutel M, et al : International consensus on allergy immunotherapy. J Allergy Clin Immunol 136 : 556-568, 2015.
PubMed
16) GINA Executive Committee : Global Initiative for Asthma ; Global Strategy for Asthma Management and Prevention. 2017 <http://ginasthma.org>
 
17) Bousquet J, et al : WHO position paper. Allergen Immunotherapy : therapeutic vaccines for allergic disease. Allergy 53 (s44) : 1-42, 1998.
 
18) Mosbech H, et al : Standardized quality (SQ) house dust mite sublingual immunotherapy tablet (ALK) reduces inhaled corticosteroid use while maintaining asthma control : a randomized, double-blind, placebo-controlled trial. J Allergy Clin Immunol 134 : 568-575, 2014.
 
19) Virchow J C, et al : Efficacy of a House Dust Mite Sublingual Allergen Immunotherapy Tablet in Adults With Allergic Asthma : A Randomized Clinical Trial. JAMA 315 : 1715-1725, 2016.
PubMed
20) Marogna M, et al : Long-term comparison of sublingual immunotherapy vs inhaled budesonide in patients with mild persistent asthma due to grass pollen. Ann Allergy Asthma Immunol 102 : 69, 2009.
PubMed
P.178 掲載の参考文献
1) Ishizaka K, et al : Physico-chemical properties of human reaginic antibody. IV. Presence of a unique immunoglobulin as a carrier of reaginic activity. J Immunol 97 : 75-85, 1966.
 
2) Ohta K, et al : Japanese gtiideline for adult asthma. Allergol Int 60 : 115-145, 2011.
PubMed
3) MacGlashan D W Jr, et al : Down-regulation of Fc (epsilon) RI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody. J Immunol 158 : 1438-1445, 1997.
PubMed
4) Chan M A, et al : Omalizumab may decrease IgE synthesis by targeting membrane IgE+ human B cells. Clin Transl Allergy 3 : 29, 2013.
 
5) Teach S J, et al : Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations. J Allergy Clin Immunol 136 : 1476-1485, 2015.
PubMed
6) Fahy J V, et al : The effect of an anti-IgE monoclonal antibody on the early-and late-phase responses to allergen inhalation in asthmatic subjects. Am J Respir Crit Care Med 155 : 1828-1834, 1997.
PubMed
7) Normansell R, et al : Omalizumab for asthma in adults and children. Cochrane Database Syst Rev CD003559, 2014.
PubMed
8) Busse W W, et al : Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children. N Engl J Med 364 : 1005-1015, 2011.
PubMed
9) Tajiri T, et al : Comprehensive efficacy of omalizumab for severe refractory asthma : a time-series observational study. Ann Allergy Asthma Immunol 113 : 470-475 e472, 2014.
 
10) Tajiri T, et al : Efficacy of omalizumab in eosinophilic chronic rhinosinusitis patients with asthma. Ann Allergy Asthma Immunol 110 : 387-388, 2013.
PubMed
11) Riccio A M, et al Omalizumab modulates bronchial reticular basement membrane thickness and eosinophil infiltration in severe persistent allergic asthma patients. Int J Immunopathol Pharmacol 25 : 475-484, 2012.
PubMed
12) Roth M, et al : The role of IgE-receptors in IgE-dependent airway smooth muscle cell remodelling. PLoS One 8 : e56015, 2013.
PubMed
13) Bousquet J, et al : Persistency of response to omalizumab therapy in severe allergic (IgE-mediated) asthma. Allergy 66 : 671-678, 2011.
PubMed
14) Braunstahl G J, et al : The eXpeRience registry : the 'real-world' effectiveness of omalizumab in allergic asthma. Respir Med 107 : 1141-1151, 2013.
PubMed
15) Tajiri T, et al : Utility of serum periostin and free IgE levels in evaluating responsiveness to omalizumab in patients with severe asthma. Allergy 71 : 1472-1479, 2016.
PubMed
16) Bousquet J, et al : Predicting response to omalizumab, an anti-IgE antibody, in patients with allergic asthma. Chest 125 : 1378-1386, 2004.
PubMed
17) Hanania N A, et al : Exploring the effects of omalizumab in allergic asthma : an analysis of biomarkers in the EXTRA study. Am J Respir Crit Care Med 187 : 804-811, 2013.
PubMed
18) Suzukawa M, et al : Baseline serum CXCL10 and IL-12 levels may predict severe asthmatics' responsiveness to omalizumab. Respir Med 134 : 95-102, 2018.
PubMed
19) Bousquet J, et al : Predicting and evaluating response to omalizumab in patients with severe allergic asthma. Respir Med 101 : 1483-1492, 2007.
PubMed
20) Korn S, et al : Monitoring free serum IgE in severe asthma patients treated with omalizumab. Respir Med 106 : 1494-1500, 2012.
PubMed
21) Molimard M, et al : Observational study in severe asthmatic patients after discontinuation of omalizumab for good asthma control. Respir Med 108 : 571-576, 2014.
PubMed
22) Kuprys-Lipinska I, et al : Loss of asthma control after cessation of omalizumab treatment : real life data. Postepy Dermatol Alergol 31 : 1-5, 2014.
PubMed
23) Ledford D, et al : A randomized multicenter study evaluating Xolair persistence of response after long-term therapy. J Allergy Clin Immunol 140 : 162-169 e162, 2017.
 
24) Nopp A, et al : After 6 years with Xolair ; a 3-year withdrawal follow-up. Allergy 65 : 56-60, 2010.
PubMed
P.187 掲載の参考文献
1) 長瀬洋之 : 喘息における分子標的薬の可能性. アレルギー 64 : 14-22, 2015.
Medical*Online
2) Pavord I D, et al : Mepolizumab for severe eosinophilic asthma (DREAM) : amulticentre, double-blind, placebo-controlled trial. Lancet 380 : 651-659, 2012.
 
3) Ortega H G, et al : MENSA Investigators. Mepolizumab treatment in patients with severe eosinophilic asthma. N Engl J Med 371 : 1198-1207, 2014.
PubMed
4) Ortega H G, et al : Severe eosinophilic asthma treated with mepolizumab stratified by baseline eosinophil thresholds : a secondary analysis of the DREAM and MENSA studies. Lancet Respir Med 4 : 549-556, 2016.
PubMed
5) Yancey S W, et al : Biomarkers for severe eosinophilic asthma. J Allergy Clin Immunol 140 : 1509-1518, 2017.
PubMed
6) Magnan A, et al : Treatment response with mepolizumab in severe eosinophilic asthma patients with previous omalizumab treatment. Allergy 71 : 1335-1344, 2016.
PubMed
7) Gunsoy N B, et al : Evaluation of Potential Continuation Rules for Mepolizumab Treatment of Severe Eosinophilic Asthma. J Allergy Clin Immunol Pract 2017 [Epub ahead of print]
 
8) Flood-Page P T, et al : Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway. Am J Respir Crit Care Med 167 : 199-204, 2003.
PubMed
9) FitzGerald J M, et al : Benralizumab, an anti-interleukin-5 receptor α monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA) : a randomised, double-blind, placebo-controlled phase 3 trial. Lancet 388 : 2128-2141, 2016.
 
10) Bleecker E R, et al : Efficacy and safety of benralizumab for patients with severe asthma uncontrolled with high-dosage inhaled corticosteroids and long-acting β2-agonists (SIROCCO) : a randomised, multicentre, placebo-controlled phase 3 trial. Lancet 388 : 2115-2127, 2016.
 
11) Nair P, et al : Oral Glucocorticoid-Sparing Effect of Benralizumab in Severe Asthma. N Engl J Med 376 : 2448-2458, 2017.
PubMed
12) Mesnil C, et al : Lung-resident eosinophils represent a distinct regulatory eosinophil subset. J Clin Invest 126 : 3279-3295, 2016.
PubMed
13) 路昭暉, 他 : 重症持続型喘息患者における分子標的薬 (Omalizumab, Mepolizumab) の適応症例の臨床背景について. アレルギー 66 : 568, 2017.
Medical*Online
14) Hanania N A, et al : Exploring the effects of omalizumab in allergic asthma : an analysis of biomarkers in the EXTRAstudy. Am J Respir Crit Care Med 187 : 804-811, 2013.
 
15) Bousquet J, et al : Care pathways for the selection of a biologic in severe asthma. Eur Respir J 50 : pii : 1701377, 2017.
 
16) Bousquet J, et al : Predicting and evaluating response to omalizumab in patients with severe allergic asthma. Respir Med 101 : 1483-1492, 2007.
PubMed
17) Le dford D, et al : A randomized multicenter study evaluating Xolair persistence of response after long-term therapy. J Allergy Clin Immunol 140 : 162-169, 2017.
 
18) Wenzel S, et al : Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist : a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial. Lancet 388 : 31-44, 2016.
 
19) Corren J, et al : Tezepelumab in Adults with Uncontrolled Asthma. N Engl J Med 377 : 936-946, 2017.
PubMed
P.198 掲載の参考文献
1) Pawankar R : Allergic diseases and asthma : a global public health concern and a call to action. World Allergy Organ J 7 : 12, 2014.
 
2) Barnett S B, et al : Costs of asthma in the United States : 2002-2007. J Allergy Clin Immunol 127 : 145-152, 2011.
PubMed
3) Cox G, et al : Asthma control during the year after bronchial thermoplasty. N Engl J Med 356 : 1327-1337, 2007.
PubMed
4) Wechsler M E, et al : Bronchial thermoplasty : Long-term safety and effectiveness in patients with severe persistent asthma. J Allergy Clin Immunol 132 : 1295-1302, 2013.
PubMed
5) Bateman E D, et al : Overall asthma control : the relationship between current control and future risk. J Allergy Clin Immunol 125 : 600-608, 8. e1-8. e6, 2010.
 
6) Bousquet J, et al : Uniform definition of asthma severity, control, and exacerbations : document presented for the World Health Organization Consultation on Severe Asthma. J Allergy Clin Immunol 126 : 926-938, 2010.
PubMed
7) Ichinose M, et al : Japanese guidelines for adult asthma 2017. Allergol Int 66 : 163-189, 2017.
PubMed
8) Ray A, et al : Current concepts of severe asthma. J Clin Invest 126 : 2394-2403, 2016.
PubMed
9) Miller J D, et al : A prospective feasibility study of bronchial thermoplasty in the human airway. Chest 127 : 1999-2006, 2005.
PubMed
10) Abtin F G, et al : Radiofrequency ablation of lung tumors : imaging features of the postablation zone. Radiographics 32 : 947-969, 2012.
PubMed
11) Danek C J, et al : Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs. J Appl Physiol 97 : 1946-1953, 2004.
 
12) Pretolani M, et al : Reduction of airway smooth muscle mass by bronchial thermoplasty in patients with severe asthma. Am J Respir Crit Care Med 190 : 1452-1454, 2014.
PubMed
13) Chakir J, et al : Effects of Bronchial Thermoplasty on Airway Smooth Muscle and CoUagen Deposidon in Asthma Ann Am Thorac Soc 12 : 1612-1618, 2015.
PubMed
14) Denner D R, et al : Airway Inflammation after Bronchial Thermoplasty for Severe Asthma. Ann Am Thorac Soc 12 : 1302-1309, 2015.
PubMed
15) Pretolani M, et al : Effectiveness of bronchial thermoplasty in patients with severe refractory asthma : Clinical and histopathologic correlations. J Allergy Clin Immunol 139 : 1176-1185, 2017.
PubMed
16) Mayse M L : J Bronchology Interv Pulmonol 14 : 115-123, 2007.
 
17) Cox G, et al : Bronchial thermoplasty for asthma. Am J Respir Crit Care Med 173 : 965-969, 2006.
PubMed
18) Pavord I D, et al : Safety and efficacy of bronchial thermoplasty in symptomatic, severe asthma. Am J Respir Crit Care Med 176 : 1185-1191, 2007.
PubMed
19) Minami D, et al : Usefulness of Bronchial Thermoplasty for Patients with a Deteriorating Lung Function. Intern Med 57 : 75-79, 2018.
PubMed
20) Langton D, et a1 : Bronchial thermoplasty in severe asthma in Australia. Intern Med J 47 : 536-541, 2017.
 
21) Iikura M, et al : Bronchial thermoplasty for severe uncontroled asthma in Japan. Allergol Int 2017 [Epub ahead of print]
 
22) Funatsu A, et al : A case of pulmonary cyst and pneumothorax after bronchial thermoplasty. Respirol Case Rep 6 : e00286, 2018.
PubMed
23) Kanemitsu Y, et al : Bronchiai thermoplasty for severe asthmatic cough. Ann Intern Med 2018 [Epub ahead of print].
 
P.210 掲載の参考文献
1) Giraud V, et al : Misuse of corticosteroid metered-dose inhaler is associated wirh decreased asthma stability. Eur Respir J 19 : 246-251, 2002.
 
2) Molimard M, et al : Chronic obstructive pulmonary disease exacerbation and inhaler device handling : real-life assessment of 2935 patients. Eur Respir J 49 : DOI 1601794, 2017.
 
3) Williams L K, et al : Relationship between adherence to inhaled corticosteroids and poor outcomes among adults with asthma. J Allergy Clin Immunol 114 : 1288-1293, 2004.
PubMed
4) Vestbo J, et al : Adherence to inhaled therapy, mortality and hospital admission in COPD. Thorax 64 : 939-943, 2009.
PubMed
5) Nimmo C J, et al : Assessment of patient acceptance and inhalation technique of a pressurized aerosol inhaler and two breath-actuated devices. Ann Pharmacother 27 : 922-927, 1993.
PubMed
6) Corsico A G, et al : Factors affecting adherence to asthma treatment in an intentional cohort of young and middle-aged adults. Respir Med 101 : 1363-1367, 2007.
 
7) Roberts R J, et al : A comparison of various types of patient instruction in the proper administration of metered inhalers. Drug Intell Clin Pharm 16 : 53-55, 59, 1982.
PubMed
8) Basheti I A, et a1 : Counseling about turbuhaler technique : needs assessment and effective strategies for community pharmacists. Respir Care 50 : 617-623, 2005.
 
9) O'Connell M B, et al : Short-and long-term retention of a nursing home education program on metered-dose inhaler technique. Ann Pharmacother 26 : 980-984, 1992.
 
10) Basheti I A, et al : Improved asthma outcomes with a simple inhaler technique intervention by community pharmacists, J Allergy Clin Immunol 119 : 1537-1538, 2007.
PubMed
11) Takemura M, et al : Optimal cut-off value and clinical usefulness of the Adherence Starts with Knowledge-12 in patients with asthma taking inhaled corticosteroids. J Thorac Dis 9 : 2350-2359, 2017.
PubMed
12) Atsuta R, et al : Assessing usability of the "Adherence Starts with Knowledge 20" (ASK-20) questionnaire for Japanese adults with bronchial asthma receiving inhaled corticosteroids long term. Allergol Int 66 : 411-417, 2017.
PubMed
13) 福井基成監, 吸入指導ネットワーク企・編 : 地域で取り組む喘息・COPD患者への吸入指導. フジメディカル出版, 大阪, 2011.
 
14) Takemura M, et al : Repeated instruction on inhalation technique improves adherence to the therapeutic regimen in asthma. J Asthma 47 : 202-208, 2010.
 
15) Takemura M, et al : Relationships between repeated instruction on inhalation therapy, medication adherence, and health status in chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis 6 : 97-104, 2011.
PubMed
16) Takemura M, et al : Effect of a network system for providing Proper inhalation technique by community pharmacists on clinical outcomes in COPD patients. Int J Chron Obstruct Pulmon Dis 8 : 239-244, 2013.
PubMed
17) Takemura M, et al : Impact of a network system for providing Proper inhalation technique by community pharmacists. J Asthma 49 : 535-541, 2012.
PubMed
P.215 掲載の参考文献
1) 平成28年度厚生労働省人口動態統計 <http://www.mhlw.go.jp/toukei/saikin/hw/jinkou/kakutei16/index.html>
 
2) 「喘息予防・管理ガイドライン 2015」作成委員会 : 喘息予防・管理ガイドライン 2015. 協和企画, 東京, 2015,
 
3) Suissa S, et al : Low-dose inhaled corticosteroids and the prevention of death from asthma. N Engl J Med 343 : 332-336, 2000.
PubMed
4) Ishihara K, et al : Increased use of inhaled corticosteroids and reduced hospitalizations in adult asthmatics : 11 years' experience in a japanese hospital. Respirology 3 : 193-197, 1998.
 
5) Tavakoli H, et al : Ten-year trends in direct costs of asthma : A population-based study. Allergy 72 : 291-299, 2017.
PubMed
6) 宮本昭正, 他 : 喘息患者に対するプロピオン酸フルチカゾンの喘息エピソードに関する医療経済的検討 fluticasone investigation of asthma episode (fine) studyより. アレルギー 55 : 542-553, 2006.
Medical*Online
7) Sadatsafavi M, et al : Saving in medical costs by achieving guideline-based asthma symptom control : A population-based study. Allergy 71 : 371-377, 2016.
PubMed
8) Sullivan P W, et al : Measuring the cost of poor asthma control and exacerbations. J Asthma 54 : 24-31, 2017.
PubMed
9) Tan N C, et al : Trends and predictors of asthma costs : Results from a 10-year longitudinal study. Eur Respir J 47 : 801-809, 2016.
PubMed
10) Sabatelli L, et al : Cost-effectiveness and budget impact of routine use of fractional exhaled nitric oxide monitoring for the management of adult asthma patients in spain. J Investig Allergol Clin Immunol 27 : 89-97, 2017.
 
11) Nurmagambetov T, et al : State-level medical and absenteeism cost of asthma in the united states. J Asthma 54 : 357-370, 2017.
PubMed
12) Rank M A, et al : Comparative safety and costs of stepping down asthma medications in patients with controlled asthma. J Allergy Clin Immunol 137 : 1373-1379 e1373, 2016.
 
P.217 掲載の参考文献
1) Ohkura N, et ai : Exp Lung Re 35 : 296, 2009.
 
2) Satia I, et al : J Allergy Clin Immunol 139 : 771, 2017.
PubMed
3) Fujimura M, et al : Cough 1 : 5, 2005.
 
4) Pounsford J C, et al : Thorax 40 : 662, 1985.
PubMed
5) Kerstjens H A, et al : N Engl J Med 367 : 1198, 2012.
PubMed
6) Alagha K, et al : Ther Adv Chronic Dis 5 : 85. 2014.
PubMed
7) Dicpinigaitis P V, et al : Lung 186 : 369, 2008.
PubMed
8) Birrell M A, et al : J Allergy Clin Immunol 133 : 679, 2014.
PubMed
9) Fukumitsu K, et al : J Allergy Clin Immunol Pract 2018 [Epub].
 

第5章 特殊病態・併存症

P.225 掲載の参考文献
1) 一般社団法人日本アレルギー学会 : 喘息予防・管理ガイドライン 2015. 協和企画東京, 2015.
 
2) Chung K F, et al : International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J 43 : 343-373, 2014.
PubMed
3) Haldar P, et al : Cluster analysis and clinical asthma phenotypes. Am J Respir Crit Care Med 178 : 218-224, 2008.
PubMed
4) Moore W C, et al : Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med 181 : 315-323, 2010.
PubMed
5) Nagasaki T, et al : Integrating longitudinal information on pulmonary function and inflammation using asthma phenotypes. J Allergy Clin Immunol 133 : 1474-1477 e2, 2014.
 
6) Buhl R, et al : Severe eosinophilic asthma : a roadmap to consensus. Eur Respir J 49 : pii : 1700634, 2017.
 
7) Brusselle G G, et al : Eosinophils in the spotlight : Eosinophilic airway inflammation in nonallergic asthma. Nat Med 19 : 977-979, 2013.
 
8) Kuo C S, et al : T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED. Eur Respir J 49 : pii : 1602135, 2017.
 
9) Nagasaki T, et al : Utility of serum periostin in combination with exhaled nitric oxide in the management of asthma. Allergol Int 66 : 404-410, 2017.
PubMed
10) Slager R E, et al : IL-4 receptor alpha polymorphisms are predictors of a pharmacogenetic response to a novel IL-4/IL-13 antagonist. J Allergy Clin Immunol 126 : 875-878, 2010.
PubMed
11) Sunadome H, et al : IL4Ralpha and ADAM33 as genetic markers in asthma exacerbations and type-2 inflammatory endotype. Clin Exp Allergy 47 : 998-1006, 2017.
PubMed
12) Dixon A E, et al : An official American Thoracic Society Workshop report : obesity and asthma. Proc Am Thorac Soc 7 : 325-335, 2010.
PubMed
13) Sutherland E R, et al : Cluster analysis of obesity and asthma phenotypes. PLoS One 7 : e36631, 2012.
PubMed
14) Green R H, et al : Asthma exacerbations and sputum eosinophil counts : a randomised controlled trial. Lancet 360 : 1715-1721, 2002.
 
15) Matsuoka H, et al : Patients'characteristics associated with unsuccessful sputum induction in asthma. J Allergy Clin Immunol 121 : 774-776, 2008.
PubMed
16) Price D B, et al : Blood eosinophil coumt and prospective annual asthma disease burden : a UK cohort study. Lancet Respir Med 3 : 849-858, 2016.
 
17) Korevaar D A, et al : Diagnostic accuracy of minimally invasive markers for detection of airway eosinophilia in asthma : a systematic review and meta-analysis. Lancet Respir Med 3 : 290-300, 2015.
PubMed
18) Fowler S J, et al : High blood eosinophil counts predict sputum eosinophilia in patients with severe asthma. J Allergy Clin Immunol 135 : 822-824 e2, 2015.
 
19) Katz L E, et al : Blood eosinophil count is a useful biomarker to identify patients with severe eosinophilic asthma. Ann Am Thorac Soc 11 : 531-536, 2014.
PubMed
20) Hanania N A, et al : Exploring the effects of omalizumab in allergic asthma : an analysis of biomarkers in the EXTRA study. Am J Respir Crit Care Med 187 : 804-811, 2013.
PubMed
21) Kharitonov S A, et al : Exhaled markers of pulmonary disease. Am J Respir Crit Care Med 163 : 1693-1722, 2001.
PubMed
22) Chibana K, et al : IL-13 induced increases in nitrite levels are primarily driven by increases in inducible nitric oxide synthase as compared with effects on arginases in human primary bronchial epithelial cells. Clin Exp Allergy 38 : 936-946, 2008.
PubMed
23) Matsunaga K, et al : Reference ranges for exhaled nitric oxide fraction in healthy Japanese adult population. Allergol Int 59 : 363-367, 2010.
PubMed
24) Matsunaga K, et al : Exhaled nitric oxide cutoff values for asthma diagnosis according to rhinitis and smoking status in Japanese subjects. Allergol Int 60 : 331-337, 2011.
PubMed
25) Dweik R A, et al : An official ATS clinical practice guideline : interpretation of exhaled nitric oxide levels (FENO) for clinical applications. Am J Respir Crit Care Med 184 : 602-615, 2011.
PubMed
26) Izuhara K, et al : Roles of Periostin in Respiratory Disorders. Am J Respir Crit Care Med 193 : 949-956, 2016.
PubMed
27) Kanemitsu Y, et al : Increased periostin associates with greater airflow limitation in patients receiving inhaled corticosteroids. J Allergy Clin Immunol 132 : 305-312 e3, 2013.
 
28) Matsusaka M, et al : Phenotype of asthma related with high serum periostin levels. Allergol Int 64 : 175-180, 2015.
PubMed
29) Matsumoto H : Serum Periostin : A Novel Biomarker for Asthma Management. Allergol Int 63 : 153-160, 2014.
PubMed
30) Wenzel S, et al : Dupilumab elificacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting beta2 agonist : a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial. Lancet 388 : 31-44, 2016.
 
31) Hanania N A, et al : Efficacy and safety of lebrikizumab in patients with uncontrolled asthma (LAVOLTA I and LAVOLTA II) : replicate, phase 3, randomised, double-blind, placebo-controlled trials. Lancet Respir Med 4 : 781-796, 2016.
PubMed
P.234 掲載の参考文献
1) 日本呼吸器学会 : 咳嗽に関するガイドライン 第2版. メディカルレビュー社, 大阪, 2012.
 
2) 新実彰男 : 慢性咳嗽の病態, 鑑別診断と治療 : 咳喘息を中心に. 日内会誌 105 : 1565-1577, 2016.
 
3) Niimi A : Geography and cough aetiology. Pulm Pharmacol Ther 20 : 383-387, 2007.
PubMed
4) Jinnai M, et al : Induced sputum concentrations of mucin in patients with asthma and chronic cough. Chest 137 : 1122-1129, 2010.
PubMed
5) Ford A C, et al : Cough in the community : a crosssectional survey and the relationship to gastrointestinal symptoms. Thorax 61 : 975-979, 2006.
PubMed
6) Fujimura M : Frequency of persistent cough and trends in seeking medical care and treatment-Results of an internet survey. Allergol Int 61 : 573-581, 2012.
PubMed
7) Matsumoto H, et al : Risks and Cough-Aggravating Factors in Prolonged Cough. Epidemiological Observations from the Nagahama Cohort Study. Ann Am Thorac Soc 14 : 698-705, 2017.
PubMed
8) Okayama M, et al : A rare case of isolated chronic cough caused by pulmonary lymphangitic carcinomatosis as a primary manifestation of rectum carcinoma. Intern Med (in press)
 
9) Tajiri T, et al : Prevalence and clinical relevance of allergic rhinitis in patients with classic asthma and cough variant asthma. Respiration 87 : 211-218, 2014.
PubMed
10) Niimi A, et al : Airway remodelling in cough-variant asthma. Lancet 356 : 564-565, 2000.
PubMed
11) Niimi A, et al : Nature of airway inflammation and remodeling in chronic cough. J Allergy Clin Immunol 116 : 565-570, 2005.
 
12) Matsuoka H, et al : Inflammatory subtypes in cough-variant asthma : association with maintenance doses of inhaled corticosteroids. Chest 138 : 1418-1425, 2010.
PubMed
13) Asano T, et al : Diagnostic utility of fractional exhaled nitric oxide in prolonged and chronic cough according to atopic status. Allergol Int 66 : 344-350, 2017.
PubMed
14) Takemura M, et al : Clinical, physiological and anti-inflammatory effect of montelukast in patients with cough variant asthma. Respiration 83 : 308-315, 2012.
PubMed
15) Niimi A : Cough associated with gastro-oesophageal reflux disease (GORD) : Japanese experience. Pulm Pharmacol Ther 47 : 59-65, 2017.
PubMed
16) Satia I, et al : Capsaicin-evoked cough responses in asthmatic patients : Evidence for airway neuronal dysfunction. J Allergy Clin Immunol 139 : 771-779, 2017.
PubMed
17) Fukumitsu K, et al : Tiotropium Attenuates Refractory Cough and Capsaicirl Cough Reflex Sensitivity in Patients with Asthma. J Allergy Clin Immunol Pract 2018 [Epub ahead of print]
 
18) Kanemitsu Y, et al : Bronchial Thermoplasty for Severe Asthmatic Cough. Ann Intern Med 2018 [Epub ahead of print]
 
19) Kanemitsu Y, et al : Gastroesophageal dysmotility is associated with the impairment of cough-specific quality of life in padents with cough variant asthma. Allergol Int 65 : 320-326, 2016.
 
20) Morice A H, et al : Cough hypersensitivity syndrome : a distinct clinical entity. Lung 189 : 73-79, 2011.
PubMed
21) Niimi A, et al : Evidence for neuropathic processes in chronic cough. Pulm Pharmacol Ther 35 : 100-104, 2015.
PubMed
P.241 掲載の参考文献
1) Dunn R M, et al : Asthma in the elderly and late-onset adult asthma. Allergy 73 (2) : 284-294, 2018.
PubMed
2) Bellia V, et al : Asthma in the elderly. European Respiratory Society Monograph 43 : 56-76, 2009.
 
3) Bai T R, et al : The effect of age and duration of disease on airway structure in fatal asthma. Am J Respir Crit Care Med 162 (2 Pt 1) : 663-669, 2000.
 
4) Inoue H, et ai : Pathophysiological characteristics of asthma in the elderly : a comprehensive study. Ann Allergy Asthma Immunol 113 (5) : 527-533, 2014.
 
5) Mathur S K, et al : Age-related changes in eosinophil function in human subjects. Chest 133 (2) : 412-419, 2008.
PubMed
6) Bozek A, et al : Adherence to asthma therapy in elderly patients. J Asthma 47 (2) : 162-165, 2010.
PubMed
7) Connolly M J, et al : Reduced subjective awareness of bronchoconstriction provoked by methacholine in elderly asthmatic and normal subjects as measured on a simple awareness scale. Thorax 47 (6) : 410-413, 1992.
PubMed
8) Wardzynska A, et al : Comorbidities in elderly patients with asthma Association with control of the disease and concomitant treatment. Geriatr Gerontol Int 15 (7) : 902-909, 2015.
PubMed
9) Battaglia S, et al : Asthma in the elderly : a different disease? Breathe (Sheff) 12 (1) : 18-28, 2016.
PubMed
10) Korn S, et al : Effectiveness of omalizumab in patients 50 years and older with severe persistent allergic asthma. Ann Allergy Asthma Immunol 105 (4) : 313-319, 2010.
PubMed
11) Ortega H, et al : Response to Treatment with Mepolizumab in Elderly Patients [abstract]. Am J Respir Crit Care Med 191 (suppl 1), A4177, 2015.
 
12) 井上英樹, 他 : 吸入指導勉強会による薬剤師の意識変化について : 京都府薬剤師会伏見支部吸入指導勉強会アンケートからの検討. Pharm Med 32 (6) : 101-106, 2014.
 
P.245 掲載の参考文献
1) Bousquet J, et al : Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol 108 : S147-334, 2001.
PubMed
2) Passalacqua G, et al : The nose-lung interaction in allergic rhinitis and asthma : united airways disease. Curr Opin Allergy Clin Immunol 1 : 7-13, 2001.
PubMed
3) Leynaert B, et al : Epidemiologic evidence for asthma and rhinitis comorbidity. J Allergy Clin Immunol 106 : S201-205, 2000.
PubMed
4) Dixon A E, et al : Allergic rhinitis and sinusitis in asthma : differential effects on symptoms and pulmonary function. Chest 130 : 429-435, 2006.
PubMed
5) Asano T, et al : Serum Periostin as a Biomarker for Comorbid Chronic Rhinosinusitis in Patients with Asthma. Ann Am Thorac Soc 14 : 667-675, 2017.
PubMed
6) Tajiri T, et al : Prevalence and clinical relevance of allergic rhinitis in patients with classic asthma and cough variant asthma. Respiration 87 : 211-218, 2014.
PubMed
7) Ohta K, et al : Prevalence and impact of rhinitis in asthma. SACRA, a cross-sectional nation-wide study in Japan. Allergy 66 : 1287-1295, 2011.
 
8) Shaaban R, et al : Rhinitis and onset of asthma : a longitudinal population-based study. Lancet 372 : 1049-1057, 2008.
PubMed
9) Gaga M, et al : Eosinophils are a feature of upper and lower airway pathology in non-atopic asthma irrespective of the presence of rhinitis. Clin Exp Allergy 30 : 663-669, 2000.
PubMed
10) Braunstahl G J, et al : Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways. Allergy Clin Immunol 107 : 469-476, 2001.
PubMed
11) Braunstahl G J, et al : Segmental bronchial provocation induces nasal inflammation in allergic rhinitis patients. Am J Respir Crit Care Med 161 : 2051-2057, 2000.
PubMed
12) Prieto L, et al : Modification of concentration-response curves to inhaled methacholine after the pollen season in subjects with pollen induced rhinitis. Thorax 49 : 711-713, 1994.
PubMed
13) Osborne N J, et al : Pollen exposure and hospitalization due to asthma exacerbations : daily time series in a European city. Int J Biometeorol 61 : 1837-1848, 2017.
 
14) Oka A, et al : Ongoing allergic rhinitis impairs asthma control by enhancing the lower airway inflammation. J Allergy Clin Immunol Pract 2 : 172-178, 2014.
PubMed
15) Lohia S, et al : Impact of intranasal corticosteroids on asthma outcomes in allergic rhinitis : a meta-analysis. Allergy 68 : 569-579, 2013.
PubMed
16) Passalacqua G, et al : Allergic rhinitis and its impact on asthma update : allergen immunotherapy. J Allergy Clin Immunol 119 : 881-891, 2007.
PubMed
17) Yatera K, et al : Prevalence of sinusitis and efficacy of intranasal corticosteroid treatment on asthmatic symptoms in asthmatic patients with rhinosinusitis : a pilot study. Int Forum Allergy Rhinol 6 : 398-406, 2016.
PubMed
18) Guerra S, et al : Rhinitis as an independent risk factor for adult-onset asthma. J Allergy Clin Immunol 109 : 419-425, 2002.
PubMed
19) Pearlman A N, et al : Relationships between severity of chronic rhinosinusitis and nasal polyposis, asthma and atopy. Am J Rhinol Allergy 23 : 145-148, 2009.
PubMed
20) Payne S C, et al : Genetics and phenotyping in chronic sinusitis. J Allergy Clin Immunol 128 : 710-720 : quiz 21-22, 2011.
 
21) Szczeklik A, et al : Natural history of aspirin-induced asthma AIANE Investigators. European Network on Aspirin-Induced Asthma. Eur Respir J 16 : 432-436, 2000.
PubMed
22) Ceylan E, et al : Nasal polyps and the severity of asthma. Respirology 12 : 272-276, 2007.
PubMed
23) Asano T, et al : Combined measurements of fractional exhaled nitric oxide and nasal nitric oxide levels for assessing upper airway diseases in asthmatic patients. J Asthma 55 : 300-309, 2018.
PubMed
24) Ehnhage A, et al : Functional endoscopic sinus surgery improved asthma symptoms as well as PEFR and olfaction in patients with nasal polyposis. Allergy 64 : 762-769, 2009.
PubMed
P.249 掲載の参考文献
1) Soler M, et al : The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics. Eur Respir J 18 : 254-261, 2001.
PubMed
2) Ohta K, et al : Prevalence and impact of rhinitis in asthmaSACRA, a cross-sectional nation-wide study in Japan. Allergy 66 : 1287-1295, 2011.
PubMed
3) Bousquet J, et al : Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol 108 (5 Suppl) : S147-334, 2001.
 
4) Braunstahl G, et al : Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways. J Allergy Clin Immunol 107 : 469-476, 2001.
PubMed
5) Corren J, et al : Changes in bronchial responsiveness following nasal provocation with allergen. J Allergy Clin Immunol 89 : 611-618, 1992.
PubMed

書評

最近チェックした商品履歴

Loading...