■Journal Club
○Ectopic germinal center—like structures in minor salivary
gland biopsy tissue predict lymphoma occurrence in patients
with primary Sjögren’s syndrome.
Sjögren’s syndrome.
○JAK—1 inhibition suppresses interferon—induced BAFF production
in human salivary gland:potential therapeutic strategy for primary
Sjögren’s syndrome.
○CRISPR—Cas9 targeting of MMP13 in human chondrocytes
leads to significantly reduced levels of the metalloproteinase
and enhanced typeⅡ collagen accumulation.
○Microbiota—dependent involvement of Th17 cells in murine
models of inflammatory arthritis.
○A randomized, controlled double—blind study comparing the
efficacy and safety of dose—ranging voclosporin with placebo
in achieving remission in patients with active lupus nephritis.
○Development and validation of a renal risk score in ANCA
—associated glomerulonephritis.
○Monoclonal antibody targeting BDCA2 ameliorates skin lesions
in systemic lupus erythematosus.
○Beyond autoantibodies:biologic roles of human autoreactive
B cells in rheumatoid arthritis revealed by RNA—sequencing.