腸内フローラと炎症

出版社： 医薬出版
著者：
発行日： 2021-08-20
分野： 基礎医学  >  医動物(寄生虫)
ISBN： 9784990673994
電子書籍版： 2021-08-20 （初版第1刷）
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目次

  • はじめに

    特別講演１　腸内細菌と自己免疫疾患

    講演１　小児アレルギー疾患と皮膚・腸内細菌叢

    講演２　腸内細菌と睡眠：プロバイオティクスの脳腸相関を介した新しい機能

    講演３　腸管と女性生殖器のマイクロビオータ：隣どうしの諠

    講演４　腸肺相関

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はじめに

P.6 掲載の参考文献
1) 神谷茂 : 腸内フローラと内科疾患, Jpn J Antibiotics, 70 : 1-13, 2017
 
2) Durack J & Lynch SV : The gut microbiome : Relationships with disease and opportunities for therapy. J Exp Med 216 : 20-40, 2019 doi. 10.1084/jem.20180448.
 
3) Foster KR et al. : The evolution of the host microbiome as an ecosystem on a leash. Nature 548 : 43-51, 2017
PubMed
4) Ahlawat S et al. : Gut-organ axis : a microbial outreach and networking. Lett Appl Micribiol 2020 May 29. doi : 10.1111/lam.13333
 
5) Wagner-Skacel J et al. : Sleep and microbiome in psychiatric diseases. nutrients 12 : 2198, 2020 doi : 10.3390/nu12082198
 
6) Evans SJ et al. : The gut microbiome composition associates with bipolar disorder and illness severity. J Psychiatr Res 87 : 23-29, 2017
PubMed
7) Aizawa E et al. : Bifidobacterium and Lactobacillus counts in the gut microbiota of patients with bipolar disorder and healthy controls. Front Psychhiatry 9 : 730, 2019
 
8) Poroyko VA et al. : Chronic sleep disruption alters gut microbiota, induces systemic and adipose tissue inflammation and insulin resistance in mice. Sci Rep 6 : 35405, 2016
PubMed
9) Tahaya Y et al. : Gut microbiota-derived short chain fatty acids induce circadian clock entrainment in mouse peripheral tissue. Sci Rep 8 : 1395, 2018
 
10) Yu L et al. : Beneficial effect of GABA-rich fermented milk on insomnia involving regulation of gut microbiota. Microbiol Res 233 : 126409, 2020
PubMed
11) Pot GK : Sleep and dietary habits in the urban environment : The role of chrono-nutrition. Proc Nutr Soc 77 : 189-198, 2018
PubMed
12) St-Onge MP et al. : Effects of diet on sleep quality. Adv Nutr 7 : 938-949, 2016
PubMed
13) Park YM et al. : Imbalance of gut Streptococcus, Clostridium, and Akkermansia determines the natural course of atopic dermatitis in infant. Allergy Asthma Immunol Res 12 : 322-337, 2020
PubMed
14) Plummer EL et al. : Lactic acid-containing products for bacterial vaginosis and their impact on the vaginal microbiota : A systematic review PLoS One 16 : e0246953, 2021
PubMed
15) Redelinghuys MJ et al. : Bacterial vaginosis : Current diagnostic avenues and future opportunities. Front Cell Infect Microbiol 10 : 354. Doi : 10.3389, 2020
 
16) Agarwal K et al. : Glycan cross-feeding supports mutualism between Fusobacterium and the vaginal microbiota. PLoS Biol 18 : e3000788, 2020 doi. 10.1371/journal.pbio.3000788.
 
17) Loverdos K et al. : Lung micribome in asthma : current perspectives. J Clin Med 8 : 1967, 2019 doi. 10.3390/jcm8111967.
 
18) Herbst T et al. : Dysregulation of allergic airway inflammation in the absence of microbial colonization. Am J Respir Crit Care Med 184 : 198-205, 2011
PubMed
19) Dom S et al. : Pre- and post-natal exposure to antibiotics and the development of eczema, recurrent wheezing and atopic sensitization in children up to the age of 4 years. Clin Exp Allergy 40 : 1378-1387, 2010
 
20) Stensballe LG et al. : Use of antibiotics during pregnancy increases the risk of asthma in early childhood. J Pediatr 162 : 832-838, 2013
PubMed

特別講演1. 腸内細菌と自己免疫疾患

P.12 掲載の参考文献
1) Sender R, Fuchs S., Milo R. Are we really vastly outnumbered? Revisiting the ratio of bacterial to host cells in humans. Cell 2016 ; 164 : 337-340.
PubMed
2) Qin J, Li R, Raes J, Arumugam M, Burgdorf KS, Manichanh C, Nielsen T, Pons N, Levenez F, Yamada T, Mende DR, Li J, Xu J, Li S, Li D, Cao J, Wang B, Liang H, Zheng H, Xie Y, Tap J, Lepage P, Bertalan M, Batto JM, Hansen T, Le Paslier D, Linneberg A, Nielsen HB, Pelletier E, Renault P, Sicheritz-Ponten T, Turner K, Zhu H, Yu C, Li S, Jian M, Zhou Y, Li Y, Zhang X, Li S, Qin N, Yang H, Wang J, Brunak S, Dore J, Guarner F, Kristiansen K, Pedersen O, Parkhill J, Weissenbach J, MetaHIT Consortium, Bork P, Ehrlich SD, Wang J. A human gut microbial gene catalogue established by metagenomic sequencing. Nature 2010 ; 464 : 59-65
 
3) Strachan DP. Hay fever, hygiene, and household size. BMJ. 1989 : 299 : 1259-1260.
PubMed
4) Bach J-F. The effect of infections on susceptibility to autoimmune and allergic diseases. N. Eng. J. Med. 2002 : 347 : 911-920
 
5) Ege MJ. The Hygiene Hypothesis in the Age of the Microbiome. Ann Am Thorac Soc. 2017 ; 14 : S348-S353.
PubMed
6) Clemente JC, Manasson J, Scher JU. The role of the gut microbiome in systemic inflammatory disease. BMJ 360 : j5145, 2018.
PubMed
7) Han H, Li Y, Fang J, Liu G, Yin J, Li T, Yin Y. Gut microbiota and type 1 diabetes. Int J Mol Sci 19 : 995, 2018.
 
8) Chu F, Shi M, Lang Y, Shen D, Jin T, Zhu J, Cui L. Gut microbiota in multiple sclerosis and experimental autoimmune encephalomyelitis : current applications and future perspectives. Mediators Inflamm 2018 : 8168717, 2018.
PubMed
9) Clark M, Kroger CJ, Tisch RM. Type 1 Diabetes : A chronic anti-self-Inflammatory response. Front Immunol. 2017 ; 8 : 1898.
PubMed
10) Kachapati K, Adams D, Bednar K, Ridgway WM. The non-obese diabetic (NOD) mouse as a model of human type 1 diabetes. Methods Mol Biol. 2012 ; 933 : 3-16.
 
11) Like AA, Rossini AA. Streptozotocin-induced pancreatic insulitis : new model of diabetes mellitus. Science. 1976 ; 193 : 415-417.
PubMed
12) Liu Q, Sundar K, Mishra PK, Mousavi G, Liu Z, Gaydo A, Alem F, Lagunoff D, Bleich D, Gause WC. Helminth infection can reduce insulitis and type 1 diabetes through CD25- and IL-10-independent mechanisms. Infect Immun. 2009 ; 77 : 5347-5358.
PubMed
13) Osada Y, Yamada S, Nabeshima A, Yamagishi Y, Ishiwata K, Nakae S, Sudo K, Kanazawa T. Heligmosomoides polygyrus infection reduces severity of type 1 diabetes induced by multiple low-dose streptozotocin in mice via STAT6- and IL-10-independent mechanisms. Exp Parasitol. 2013 ; 135 : 388-396.
PubMed
14) Shimokawa C, Kato T, Takeuchi T, Ohshima N, Furuki T, Ohtsu Y, Suzue K, Imai T, Obi S, Olia A, Izumi T, Sakurai M, Arakawa H, Ohno H, Hisaeda H. CD8+ regulatory T cells are critical in prevention of autoimmune-mediated diabetes. Nat Commun. 2020 ; 11 : 1922.
PubMed
15) Dobson R, Giovannoni G. Multiple sclerosis-a review. Eur J Neurol 26 : 27-40, 2019.
PubMed
16) Miyake S, Kim S, Suda W, Oshima K, Nakamura M, Matsuoka T, Chihara N, Tomita A, Sato W, Kim SW, Morita H, Hattori M, Yamamura T. Dysbiosis in the gut microbiota of patients with multiple sclerosis, with a striking depletion of species belonging to clostridia XIVa and IV clusters. PLoS One. 2015 ; 10 : e0137429.
PubMed
17) Jangi S, Gandhi R, Cox LM, Li N, von Glehn F, Yan R, Patel B, Mazzola MA, Liu S, Glanz BL, Cook S, Tankou S, Stuart F, Melo K, Nejad P, Smith K, Topcuolu BD, Holden J, Kivisakk P, Chitnis T, De Jager PL, Quintana FJ, Gerber GK, Bry L, Weiner HL. Alterations of the human gut microbiome in multiple sclerosis. Nat Commun. 2016 ; 7 : 12015.
PubMed
18) Chen J, Chia N, Kalari KR, Yao JZ, Novotna M, Paz Soldan MM, Luckey DH, Marietta EV, Jeraldo PR, Chen X, Weinshenker BG, Rodriguez M, Kantarci OH, Nelson H, Murray JA, Mangalam AK. Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls. Sci Rep. 2016 ; 6 : 28484.
PubMed
19) Constantinescu CS, Farooqi N, O'Brien K, Gran B. Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS). Br J Pharmacol. 2011 ; 164 : 1079-1106.
 
20) Yokote H, Miyake S, Croxford JL, Oki S, Mizusawa H, Yamamura T. NKT cell-dependent amelioration of a mouse model of multiple sclerosis by altering gut flora. Am J Pathol. 2008 ; 173 : 1714-1723.
PubMed
21) Berer K, Mues M, Koutrolos M, Rasbi ZA, Boziki M, Johner C, Wekerle H, Krishnamoorthy G. Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination. Nature 2011 ; 479 : 538-541.
PubMed
22) Lee YK Menezes JS, Umesaki Y, Mazmanian SK. Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis. Proc Notl Acad Sci U S A. 2011 ; 108 : 4615-4622.
 
23) Miyauchi E, Kim SW, Suda W, Kawasumi M, Onawa S, Taguchi-Atarashi N, Morita H, Taylor TD, Hattori M, Ohno H. Gut microorganisms act together to exacerbate inflammation in spinal cords. Nature. 2020585 : 102-106.
PubMed

講演1. 小児アレルギー疾患と皮膚・腸内細菌叢

P.24 掲載の参考文献
1) du Toit G, et al. Prevention of food allergy. J Allergy Clin Immunol 2016 ; 137 : 998-1010.
PubMed
2) Bjorksten B, et al. Allergy development and the intestinal microflora during the first year of life. J Allergy Clin Immunol. 2001 ; 108 : 516-20.
 
3) Suzuki S, et al. Differences in the composition of intestinal Bifidobacterium species and the development of allergic diseases in infants in rural Japan. Clin Exp Allergy. 2007 ; 37 : 506-11.
PubMed
4) Nakano T, et al. Breastfeeding promotes egg white sensitization in early infancy. Pediatr Allergy Immunol. 2020 ; 31 : 315-8.
PubMed
5) Tanabe H, et al. Association of the maternal microbiome in Japanese pregnant women with the cumulative prevalence of dermatitis in early infancy : A pilot study from the Chiba study of Mother and Child Health birth cohort. World Allergy Organ J. 2019 ; 12 : 100065.
 
6) Kalliomaki M, et al. Probiotics in primary prevention of atopic disease : a randomised placebo-controlled trial. Lancet 2001 ; 357 : 1076-9.
PubMed
7) Dissanayake E, et al. Skin care and synbiotics for prevention of atopic dermatitis or food allergy in newborn infants : A 2×2 factorial, randomized, non-treatment controlled trial. Int Arch Allergy Immunol 2019 ; 180 : 202-11.
 
8) Panduru M, et al. Probiotics and primary prevention of atopic dermatitis : a meta-analysis of randomized controlled studies. Eur Acad Dermatol Venereol. 2015 ; 29 : 232-242.
PubMed
9) Canani RB, et al. Lactobacillus rhamnosus GG-supplemented formula expands butyrate-producing bacterial strains in food allergic infants. ISME J. 2016 ; 10 : 742-50.
 
10) Nakamura Y, et al. Staphylococcus Agr virulence is critical for epidermal colonization and associates with atopic dermatitis development. Sci Transl Med. 2020 ; 12 : eaay4068.
PubMed

講演2. 腸内細菌と睡眠 : プロバイオティクスの脳腸相関を介した新しい機能

P.29 掲載の参考文献
1) Cryan JF, Dinan TG. Mind-altering microorganisms : The impact of the gut microbiota on brain and behaviour. Nat Rev Neurosci. 2012 ; 13 (10) : 701-712.
PubMed
2) 須藤信行. 脳機能と腸内細菌叢. 腸内細菌学雑誌. 2017 ; 31 (1) : 23-32.
Medical*Online
3) 六反一仁. 脳腸相関 : 脳と腸の密接なつながり知る. ソフト・ドリンク技術資料. 2015 ; 1 : 35-47.
 
4) 六反, 一仁, 桑野, 由紀, 西田, 憲生. ストレスと腸内細菌叢 : 乳酸菌を用いた新たな健康戦略. ストレス科学. 2019 ; 33 (4) : 331-344.
Medical*Online
5) Sudo N, Chida Y, Aiba Y, et al. Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice. J Physiol. 2004 ; 558 (1) : 263-275.
 
6) Gaykema RPA, Goehler LE, Lyte M. Brain response to cecal infection with Campylobacter jejuni : Analysis with Fos immunohistochemistry. Brain Behav Immun. 2004 ; 18 (3) : 238-245.
PubMed
7) Goehler LE, Park SM, Opitz N, Lyte M, Gaykema RPA. Campylobacter jejuni infection increases anxiety-like behavior in the holeboard : Possible anatomical substrates for viscerosensory modulation of exploratory behavior. Brain Behav Immun. 2008 ; 22 (3) : 354-366.
PubMed
8) Goehler LE, Gaykema RPA, Opitz N, Reddaway R, Badr N, Lyte M. Activation in vagal afferents and central autonomic pathways : Early responses to intestinal infection with Campylobacter jejuni. Brain Behav Immun. 2005 ; 19 (4) : 334-344.
 
9) Hsiao EY, Mcbride SW, Hsien S, et al. Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders. Cell. 2013 ; 155 (7) : 1451-1463.
PubMed
10) Buffington SA, Di Prisco GV, Auchtung TA, Ajami NJ, Petrosino JF, Costa-Mattioli M. Microbial reconstitution reverses maternal diet-induced social and synaptic deficits in offspring. Cell. 2016 ; 165 (7) : 1762-1775.
PubMed
11) Sharon G, Cruz NJ, Kang D, et al. Human gut microbiota from autism spectrum disorder promote behavioral symptoms in mice article human gut microbiota from autism spectrum disorder promote behavioral symptoms in mice. Cell. 2019 ; 177 (6) : 1600-1618.
PubMed
12) Kato-Kataoka A, Nishida K, Takada M, et al. Fermented milk containing Lactobacillus casei strain Shirota preserves the diversity of the gut microbiota and relieves abdominal dysfunction in healthy medical students exposed to academic stress. Appl Environ Microbiol. 2016 ; 82 (12) : 3649-3658.
PubMed
13) Kato-Kataoka A, Nishida K, Takada M, et al. Fermented milk containing Lactobacillus casei strain Shirota prevents the onset of physical symptoms in medical students under academic examination stress. Benef Microbes. 2016 ; 7 (2) : 153-156.
PubMed
14) Takada M, Nishida K, Kataoka-Kato A, et al. Probiotic Lactobacillus casei strain Shirota relieves stress-associated symptoms by modulating the gut-brain interaction in human and animal models. Neurogastroenterol Motil. 2016 ; 28 (7) : 1027-1036.
PubMed
15) Reis DJ, Ilardi SS, Punt SEW. The anxiolytic effect of probiotics : A systematic review and meta-analysis of the clinical and preclinical literature. PLoS One. 2018 ; 13 (6).
PubMed
16) Liu RT, Walsh RFL, Sheehan AE. Prebiotics and probiotics for depression and anxiety : A systematic review and meta-analysis of controlled clinical trials. Neurosci Biobehav Rev. 2019 ; 102 : 13-23.
PubMed
17) Wang H, Lee I, Braun C, Enck P. Effects of probioitcs on central nervous system functions in animals and humans. J neurogastroenterol Motil. 2016 ; 22 (4) : 589-605.
 
18) Konturek PC, Brzozowski T, Konturek SJ. Gut clock : implication of circadian rhythms in the gastrointestinal tract. J Physiol Pharmacol. 2011 : 62 (2) : 139-150.
PubMed
19) Stokes K, Cooke A, Chang H, Weaver DR, Breault DT, Karpowicz P. The circadian clock gene BMAL1 coordinates intestinal regeneration. Cmgh. 2017 ; 4 (1) : 95-114.
PubMed
20) Thaiss CA, Zeevi D, Levy M, et al. Transkingdom control of microbiota diurnal oscillations promotes metabolic homeostasis. Cell. 2014 ; 159 (3) : 514-529.
PubMed
21) Benedict C, Vogel H, Jonas W, et al. Gut microbiota and glucometabolic alterations in response to recurrent partial sleep deprivation in normal-weight young individuals. Mol Metab. 2016 ; 5 (12) : 1175-1186.
PubMed
22) Brown R, Price RJ, King MG, Husband AJ. Are antibiotic effects on sleep behavior in the rat due to modulation of gut bacteria? Physiol Behav. 1990 ; 48 (4) : 561-565.
PubMed
23) Thompson RS, Roller R, Mika A, et al. Dietary prebiotics and bioactive milk fractions improve NREM sleep, enhance REM sleep rebound and attenuate the stress-induced decrease in diurnal temperature and gut microbial alpha diversity. Front Behav Neurosci. 2017 ; 10 (January) : 240.
 
24) 山本由華吏, 田中秀樹, 高瀬美紀, 山崎勝男, 阿住一雄, 白川修一郎. 中高年・高齢者を対象としてOSA睡眠調査票 (M版) の開発と標準化. 脳と精神の医学. 1999 ; 10 (4) : 401-409.
 
25) Takada M, Nishida K, Gondo Y, et al. Beneficial effects of Lactobacillus casei strain Shirota on academic stressinduced sleep disturbance in healthy adults : A double-blind, randomised, placebo-controlled trial. Benef Microbes. 2017 ; 8 (2) : 153-162.
PubMed
26) Knutson KL, Ryden AM, Mander BA, Van Cauter E. Role of sleep duration and quality in the risk and severity of type 2 diabetes mellitus. Arch Intern Med. 2006 ; 166 (16) : 1768-1774.
PubMed
27) Taheri S. The link between short sleep duration and obesity : We should recommend more sleep to prevent obesity. Arch Dis Child. 2006 ; 91 (11) : 881-884.
PubMed
28) Kasasbeh E, Chi DS, Krishnaswamy G. Inflammatory aspects of sleep apnea and their cardiovascular consequences. South Med J. 2006 ; 99 (1) : 58-67.
PubMed

講演3. 腸管と女性生殖器のマイクロビオータ : 隣どうしの誼

P.36 掲載の参考文献
1) Takada K, Komine-Aizawa S, Tsuji N, Hayakawa S. Chapter 20. Interactions between the epithelial barrier and the microbiota in the reproductive tract. Reproductive Immunology : Basic Concepts Academic Press. 2021 : 387-414.
 
2) Takada K, Komine-Aizawa S, Kuramochi T, Ito S, Trinh QD, Pham NTK, Sasano M, Hayakawa S. Lactobacillus crispatus accelerates re-epithelialization in vaginal epithelial cell line MS74. Am J Reprod Immunol. 2018 Sep ; 80 (3) : e13027.
PubMed
3) Lei J, Ploner A, Elfstrom KM, Wang J, Roth A, Fang F, Sundstrom K, Dillner J, Sparen P. HPV vaccination and the risk of invasive cervical cancer. N Engl. J Med. 2020 Oct 1 ; 383 (14) : 1340-1348
 
4) Mitra A, MacIntyre DA, Ntritsos G, Smith A, Tsilidis KK, Marchesi JR, Bennett PR, Moscicki AB, Kyrgiou M. The vaginal microbiota associates with the regression of untreated cervical intraepithelial neoplasia 2 lesions. Nat Commun. 2020 Apr 24 ; 11 (1) : 1999.
PubMed
5) Chen Y, Qiu X, Wang W, Li D, Wu A, Hong Z, Di W, Qiu L. Human papillomavirus infection and cervical intraepithelial neoplasia progression are associated with increased vaginal microbiome diversity in a Chinese cohort. BMC Infect Dis. 2020 Aug 26 ; 20 (1) : 629.
 
6) Komine-Aizawa S, Hirohata N, Aizawa S, Abiko Y, Hayakawa S. Porphyromonas gingivalis lipopolysaccharide inhibits trophoblast invasion in the presence of nicotine. Placenta 2015 Jan ; 36 (1) : 27-33.
PubMed
7) Hirohata N, Komine-Aizawa S, Tamura M, Ochiai K, Sugitani M, Hayakawa S. Porphyromonas gingivalis Suppresses Trophoblast Invasion by Soluble Factors. J Periodontol. 2017 Dec ; 88 (12) : 1366-1373.
PubMed
8) Yoshida T, Takada K, Komine-Aizawa S, Kamei Y, Ishihara O, Hayakawa S. Trophoblast invasion is promoted by the vaginal lactic acid bacteria Lactobacillus crispotus. Submitted.
 
9) Cabrera-Rubio R, Collado MC, Laitinen K, Salminen S, Isolauri E, Mira A. The human milk microbiome changes over lactation and is shaped by maternal weight and mode of delivery. Am J Clin Nutr. 2012 Sep ; 96 (3) : 544-51.
PubMed
10) Komie-Aizawa S, Ito S, Aizawa S, Namiki T, Hayakawa S. Cow milk exosomes activate NK cells and γδT cells in human PBMCs in vitro. Immunol Med. 2020 Dec : 43 (4) : 161-170.
 

講演4. 腸肺相関

P.44 掲載の参考文献
1) Barcik W, et al, The role of lung and gut microbiota in the pathology of asthma. Immunity. 2020 18 ; 52 (2) : 241-255.
 
2) Herbst T, et al. Dysregulation of allergic airway inflammation in the absence of microbial colonization. Am J Respir Crit Care Med. 2011 15 ; 184 (2) : 198-205.
 
3) Arrieta MC, et al. Early infancy microbial and metabolic alterations affect risk of childhood asthma. Sci Transl Med. 2015 30 ; 7 (307) : 307ra152.
 
4) Zimmermann P, et al. Association between the intestinal microbiota and allergic sensitization, eczema, and asthma : A systematic review. J Allergy Clin Immunol. 2019 ; 143 (2) : 467-485.
PubMed
5) Thavagnanam S, Fleming J, Bromley A, Shields MD, Cardwell CR. A meta-analysis of the association between Caesarean section and childhood asthma. Clin Exp Allergy. 2008 ; 38 (4) : 629-33.
PubMed
6) Korpela K, et al. Maternal fecal microbiota transplantation in Cesarean-born infants rapidly restores normal gut microbial development : A proof-of-concept study. Cell. 2020 15 ; 183 (2) : 324-334.
 
7) Kim Y, et al. Gut dysbiosis promotes M2 macrophage polarization and allergic airway inflammation via fungi-induced PGE2. Cell Host Microbe. 2014 15 ; 15 (1) : 95-102.
PubMed
8) Lee SH, et al. Association between cigarette smoking status and composition of gut microbiota : Population-based cross-sectional study. J Clin Med. 2018 : 7 (9) : 282.
PubMed
9) Reale M, et al. Daily intake of Lactobacillus casei Shirota increases natural killer cell activity in smokers. Br J Nutr. 2012 108, 308-314.
PubMed
10) Tomoda K, et al. Whey peptide-based enteral diet attenuated elastase-induced emphysema with increase in short chain fatty acids in mice. BMC Pulm Med. 2015 ; 15 : 64.
PubMed
11) Sugawara Ket al. Effect of anti-inflammatory supplementation with whey peptide and exercise therapy in patients with COPD. Respir Med. 2012 ; 106 (11) : 1526-34.
 
12) Badran M, et al. Fecal microbiota transplantation from mice exposed to chronic intermittent hypoxia elicits sleep disturbances in naive mice. Exp Neurol. 2020 ; 334 : 113439.
PubMed

SUMMARY : Intestinal Microbiota and Inflammation - Association with Symbiota

P.50 掲載の参考文献
1) Sender R, Fuchs S, Milo, R. : Are we really vastly outnumbered? Revisiting the ratio of bacterial to host cells in humans. Cell 164 : 337-340, 2016.
PubMed
2) Clemente JC, Manasson J, Scher JU. : The role of the gut microbiome in systemic inflammatory disease. BMJ 360 : j5145, 2018.
PubMed
3) Chu F, Shi M, Lang Y, et al. : Gut microbiota in multiple sclerosis and experimental autoimmune encephalomyelitis : current applications and future perspectives. Mediators Inflamm 2018 : 8168717, 2018.
PubMed
4) Han H, Li Y, Fang J, et al. : Gut microbiota and type 1 diabetes. Int J Mol Sci 19 : 995, 2018.
 
5) Dobson R, Giovannoni G. Multiple sclerosis-a review. Eur J Neurol 26 : 27-40, 2019.
PubMed
6) Miyauchi E, Kim S-W, Suda W, et al. : Gut microbes act in concert to exacerbate inflammation in spinal cords. Nature in press
 
7) Furman BL. : Streptozotocin-induced diabetic models in mice and rats. Curr Protoc Pharmacol 70 : 5.47.1-5.47.20, 2015
 
8) Shimokawa C, Kato T, Takeuchi T, et al. : CD8+ regulatory T cells are critical in prevention of autoimmune-mediated diabetes. Nat Commun 11 : 1922, 2020.
PubMed

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