わかりやすい核医学 第2版

出版社: 文光堂
著者:
発行日: 2022-01-14
分野: 臨床医学:一般  >  放射線/核医学
ISBN: 9784830637643
電子書籍版: 2022-01-14 (第2版第1刷)
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難しくなりがちな核医学を,病態生理から検査の進め方,画像の読み方へと解説を進めることにより,誰にでも理解しやすい構成となっている.2015年発行の第1版から最近進化の目覚ましい内用療法や,PETについて大幅に加筆し,最新の内容を盛り込んだ.また,読影の鍵になるものも追加し,基礎から最新の話題までを網羅した.放射線科専門医をめざす若手医師はもちろん,核医学検査,内用療法が必要な診療領域の医師・技師すべてを対象とした,“みんなのための核医学のテキスト”待望の第2版.

目次

  • I 核医学で知っておくべき最低限の基礎知識
     A.放射能・放射線の基礎
     B.放射性医薬品
     C.核医学装置
     D.画像解析

    II 脳神経
     
    III 循環器
     A.心筋血流シンチグラフィ
     B.心臓交感神経イメージング
     C.心臓脂肪酸代謝
     D.心臓糖代謝イメージング
     E.ピロリン酸イメージング
     F.心プールシンチグラフィ

    IV 呼吸器

    V 内分泌
     A.甲状腺
     B.副甲状腺
     C.副腎
     D.神経内分泌腫瘍

    VI 骨

    VII 消化器
     A.唾液腺
     B.肝臓
     C.胆道
     D.消化管出血
     E.Meckel憩室

    VIII 腎・泌尿器

    IX 腫瘍
     A.基礎
     B.生理的集積
     C.脳
     D.頭頸部
     E.胸部
     F.腹部
     G.生殖器
     H.悪性リンパ腫
     I.その他のがん

    X 炎症

    XI リンパ節・リンパ管
     A.センチネルリンパ節
     B.リンパ管シンチグラフィ

    XII 内用療法
     A.基礎
     B.甲状腺癌
     C.Basedow病
     D.前立腺癌骨転移
     E.悪性リンパ腫
     F.膵・消化管神経内分泌腫瘍
     G.交感神経系神経内分泌腫瘍

    XIII 核医学の今後の発展

この書籍の参考文献

参考文献のリンクは、リンク先の都合等により正しく表示されない場合がありますので、あらかじめご了承下さい。

本参考文献は電子書籍掲載内容を元にしております。

I 核医学で知っておくべき最低限の基礎知識

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II 脳神経

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1) Torosyan, N et al : Neuronuclear imaging in the evaluation of dementia and mild decline in cognition. Semin Nucl Med 42 : 415-422, 2012
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III 循環器

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IV 呼吸器

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V 内分泌

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VI 骨

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VII 消化器

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VIII 腎・泌尿器

P.185 掲載の参考文献
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6) Sfakianakis, GN et al : A renal protocol for all ages and all indications : mercapto-acetyl-triglycine (MAG3) with simultaneous injection of furosemide (MAG3-F0) : a 17-year experience. Semin Nucl Med 39 : 156-173, 2009
7) Levey, AS et al : A new equation to estimate glomerular filtration rate. Ann Intern Med 150 : 604-612, 2009
8) Edefonti, A et al : Febrile urinary tract infection : clinical and laboratory diagnosis, imaging, and prognosis. Semin Nucl Med 44 : 123-128, 2014

IX 腫瘍

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3) Kyzas, PA et al : 18 F-fluorodeoxyglucose positron emission tomography to evaluate cervical node metastases in patients with head and neck squamous cell carcinoma : a meta-analysis. J Natl Cancer Inst 100 : 712-720, 2008
4) Liao, LJ et al : Detection of cervical lymph node metastasis in head and neck cancer patients with clinically N0 neck-a meta-analysis comparing different imaging modalities. BMC Cancer 12 : 236, 2012
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1) UICC日本委員会TNM委員会訳 : TNM悪性腫瘍の分類 第8版 日本語版, 金原出版, 東京, p109, 2017
2) 日本肺癌学会編 : 肺癌取扱い規約 第8版補訂版, 金原出版, 東京, p7, 2021
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2) Nomori, H et al : Fluorine 18-taggedfluorodeoxyglucose positron emission tomographic scanning to predict lymph node metastasis, invasiveness, or both, in clinical T1N0M0 lung adenocarcinoma. J Thorac Cardiovasc Surg 128 : 396-401, 2004
3) Naruke, T et al : Lymph node sampling in lung cancer : how should it be done? Eur J Cardiothorac Surg 16 (Suppl 1) : S17-S24, 1999
4) Flores, RM : The role of PET in the surgical management of malignant pleural mesothelioma. Lung Cancer 49 (Suppl 1) : S27-S32, 2005
5) Treglia, G et al : Is (18) F-FDG PET useful in predicting the WHO grade of malignancy in thymic epithelial tumors? A meta-analysis. Lung Cancer 86 : 5-13, 2014
6) Otsuka, H : The utility of FDG-PET in the diagnosis of thymic epithelial tumors. J Med Invest 59 : 225-234, 2012
7) Beaulieu, S et al : Positron emission tomography of schwannomas : emphasizing its potential in preoperative planning. AJR Am J Roentgenol 182 : 971-974, 2004
8) Ezuddin, S et al : MIBG and FDG PET findngs in a patient with malignant pheochromocytoma : a significant discrepancy. Clin Nucl Med 30 : 579-581, 2005
9) 日本食道学会編 : 食道癌取扱い規約 第11版, 金原出版, 東京, 2015
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11) van Vliet, EP et al : Staging investigations for oesophageal cancer : a meta-analysis. Br J Cancer 98 : 547-557, 2008
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13) Gillies, RS et al : Additional benefit of 18F-fluorodeoxyglucose integrated positron emission tomography/computed tomography in the staging of oesophageal cancer. Eur Radiol 21 : 274-280, 2011
14) Ngamruengphong, S et al : Assessment of response to neoadjuvant therapy in esophageal cancer : an updated systematic review of diagnostic accuracy of endoscopic ultrasonography and fluorodeoxyglucose positron emission tomography. Dis Esophagus 23 : 216-231, 2010
15) 日本乳癌学会編 : 乳癌取扱い規約 第18版, 金原出版, 東京, 2018
16) Cooper, KL et al : Positron emission tomography (PET) for assessment of axillary lymph node status in early breast cancer : A systematic review and meta-analysis. Eur J Surg Oncol 37 : 187-198, 2011
17) Eubank, WB et al : Impact of FDG PET on defining the extent of disease and on the treatment of patients with recurrent or metastatic breast cancer. AJR Am J Roentgenol 183 : 479-486, 2004
18) Aukema, TS et al : The role of FDG PET/CT in patients with locoregional breast cancer recurrence : a comparison to conventional imaging techniques. Eur J Surg Oncol 36 : 387-392, 2010
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1) Petrowsky, H et al : Impact of integrated positron emission tomography and computed tomography on staging and management of gallbladder cancer and cholangiocarcinoma. J Hepatol 45 : 43-50, 2006
2) Kitajima, K et al : Clinical impact of whole body FDG-PET for recurrent biliary cancer : a multicenter study. Ann Nucl Med 23 : 709-715, 2009
2) Yamada, A et al : Evaluation of 2-deoxy-2- [18F] fluoro-D-glucose positron emission tomography in gastric carcinoma : relation to histological subtypes, depth of tumor invasion, and glucose transporter-1 expression. Ann Nucl Med 20 : 597-604, 2006
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4) Asagi, A et al : Utility of contrast-enhanced FDG PET/CT in the clinical management of pancreatic cancer : impact on diagnosis, staging, evaluation of treatment response, and detection of recurrence. Pancreas 42 : 11-19, 2013
4) Ott, K et al : Prediction of response to preoperative chemotherapy in gastric carcinoma by metabolic imaging : results of a prospective trial. J Clin Oncol 21 : 4604-4610, 2003
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7) Hatano, E et al : Preoperative positron emission tomography with fluorine-18-fluorodeoxyglucose is predictive of prognosis in patients with hepatocellular carcinoma after resection. World J Surg 30 : 1736-1741, 2006
8) Kong, YH et al : Positron emission tomography with fluorine-18-fluorodeoxyglucose is useful for predicting the prognosis of patients with hepatocellular carcinoma. Korean J Hepatol 10 : 279-287, 2004
9) Anderson, CD et al : Fluorodeoxyglucose PET imaging in the evaluation of gallbladder carcinoma and cholangiocarcinoma. J Gastrointest Surg 8 : 90-97, 2004
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11) 日本泌尿器科学会ほか編 : 膀胱癌取扱い規約 第3版, 金原出版, 東京, 2001
12) Maffione, AM et al : Diagnostic accuracy and impact on management of (18) F-FDG PET and PET/CT in colorectal liver metastasis : a meta-analysis and systematic review. Eur J Nucl Med Mol Imaging 42 : 152-163, 2015
13) Akhurst, T et al : Recent chemotherapy reduces the sensitivity o [f 18F] fluorodeoxyglucose positron emission tomography in the detection of colorectal metastases. J Clin Oncol 23 : 8713-8716, 2005
14) Ozkan, E et al : The role of 18F-FDG PET/CT in detecting colorectal cancer recurrence in patients with elevated CEA levels. Nucl Med Commun 33 : 395-402, 2012
15) 大腸癌研究会編 : 大腸癌取扱い規約 第9版, 金原出版, 東京, 2018
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1) 日本泌尿器科学会ほか編 : 前立腺癌取扱い規約 第4版, 金原出版, 東京, 2010
1) Chang, CH et al : Detecting metastatic pelvic lymph nodes by 18F-2-deoxyglucose positron emission tomography in patients with prostate specific antigen relapse after treatment for localized prostate cancer. Urol Int 70 : 311-315, 2003
2) Schoder, H et al : 2- [18F] -fluoro-2-deoxyglucose positron emission tomography for the detection of disease in patients with prostatic specific antigen relapse after radical prostatectomy. Clin Cancer Res 11 : 4761-4769, 2005
2) Grigsby, PW et al : Lymph node staging by positron emission tomography in patients with carcinoma of the cervix. J Clin Oncol 19 : 3745-3749, 2001
3) Liu, Y : Diagnostic role of fluorodeoxyglucose positron emission tomography-computed tomography in prostate cancer. Oncol Lett 7 : 2013-2018, 2014
4) Jadvar, H : Imaging evaluation of prostate cancer with 18F-fluorodeoxyglucose PET/CT : utility and Limitations. Eur J Nucl Med Mol Imaging 40 (Suppl 1) : S5-S10, 2013
5) Lee, ST et al : PET in prostate and bladder tumors. Semin Nucl Med 42 : 231-246, 2012
6) 日本産科婦人科学会ほか編 : 子宮体癌取扱い規約 第3版, 金原出版, 東京, 2012
7) Lee, SI et al : Evaluation of gynecologic cancer with MR imaging, 18F-FDG PET/CT, and PET/MR imaging. J Nucl Med 56 : 436-443, 2015
8) De Gaetano, AM et al : Imaging of gynecologic malignancies with FDG PET-CT : case examples, physiologic activity, and pitfalls. Abdom Imaging 34 : 696-711, 2009
9) Grant, P et al : Gynecologic oncologic imaging with PET/CT. Semin Nucl Med 44 : 461-478, 2014
10) 日本産科婦人科学会ほか編 : 子宮頸癌取扱い規約 第3版, 金原出版, 東京, 2012
11) Lee, SI et al : Evaluation of gynecologic cancer with MR imaging, 18F-FDG PET/CT, and PET/MR imaging. J Nucl Med 56 : 436-443, 2015
12) 日本産科婦人科学会ほか編 : 卵巣腫瘍取扱い規約 第1部 第2版, 金原出版, 東京, 2009
13) Fuccio, C et al : Noninvasive and invasive staging of ovarian cancer Review of the literature. Clin Nucl Med 36 : 889-893, 2011
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2) Engert, A et al : Reduced-intensity chemotherapy and PET-guided radiotherapy in patients with advanced stage Hodgkin's lymphoma (HD 15 trial) : a randomised, open-label, phase 3 non-inferiority trial. Lancet 379 : 1791-1799, 2012
3) Mikhaeel, NG et al : 18-FDG-PET for the assessment of residual masses on CT following treatment of lymphomas. Ann Oncol 11 (Suppl 1) : 147-150, 2000
4) Pregno, P et al : Interim 18-FDG-PET/CT failed to predict the outcome in diffuse large B-cell lymphoma patients treated at the diagnosis with rituximab-CHOP. Blood 119 : 2066-2073, 2012
5) Rohatiner, A et al : Report on a workshop convened to discuss the pathological and staging classifications of gastrointestinal tract lymphoma. Ann Oncol 5 : 397-400, 1994
6) Cheson, BD et al : Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma : the Lugano classification. J Clin Oncol 32 : 3059-3068, 2014
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1) Jimenez-Requena, F et al : Meta-analysis of the performance of (18) F-FDG PET in cutaneous melanoma. Eur J Nucl Med Mol Imaging 37 : 284-300, 2010
2) Mirk, P et al : Comparison between F-Fluorodeoxyglucose Positron Emission Tomography and Sentinel Lymph Node Biopsy for Regional Lymph Nodal Staging in Patients with Melanoma : A Review of the Literature. Radiol Res Pract 2011 : 912504, 2011
3) Kwee, TC et al : Combined FDG-PET/CT for the detection of unknown primary tumors : systematic review and meta-analysis. Eur Radiol 19 : 731-744, 2009
4) Kwee, TC et al : FDG PET/CT in carcinoma of unknown primary. Eur J Nucl Med Mol Imaging 37 : 635-644, 2010
5) Lee, JR et al : Detection of occult primary tumors in patients with cervical metastases of unknown primary tumors : comparison of (18) F FDG PET/CT with contrast-enhanced CT or CT/MR imaging-prospective study. Radiology 274 : 764-771, 2015
6) Harrison, DJ et al : The Role of 18F-FDG-PET/CT in Pediatric Sarcoma. Semin Nucl Med 47 : 229-241, 2017
7) Albano, D et al : Clinical and Prognostic Role of 18F-FDG PET/CT in Pediatric Ewing Sarcoma. J Pediatr Hematol Oncol 42 : e79-e86, 2020
8) Bar-Sever, Z et al : Guidelines on nuclear medicine imaging in neuroblastoma. Eur J Nucl Med Mol Imaging 45 : 2009-2024, 2018
9) Yanik, GA et al : Validation of Postinduction Curie Scores in High-Risk Neuroblastoma : A Children's Oncology Group and SIOPEN Group Report on SIOPEN/HR-NBL1. J Nucl Med 59 : 502-508, 2018
10) Ladenstein, R et al : Validation of the mIBG skeletal SIOPEN scoring method in two independent high-risk neuroblastoma populations : the SIOPEN/HR-NBL1 and COG-A3973 trials. Eur J Nucl Med Mol Imaging 45 : 292-305, 2018
P.262 掲載の参考文献
1) 日本核医学会 : 小児核医学検査適正施行のコンセンサスガイドライン 2020. http://jsnm.org/wp_jsnm/wp-content/uploads/2019/03/小児核医学検査適正施行のコンセンサスガイドライン2020.pdf (2021年9月閲覧)

X 炎症

P.272 掲載の参考文献
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2) 日本サルコイドーシス/肉芽腫性疾患学会 診断基準改訂委員会 : サルコイドーシスの診断基準と診断の手引き-2006. 日サルコイドーシス肉芽腫会誌 27 : 89-102, 2007
3) Ishida, Y et al : Recommendations for (18) F-fluorodeoxyglucose positron emission tomography imaging for cardiac sarcoidosis : Japanese Society of Nuclear Cardiology recommendations. Ann Nucl Med 28 : 393-403, 2014
4) Zhang, J et al : Characterizing IgG4-related disease with 18F-FDG PET/CT : a prospective cohort study. Eur J Nucl Med Mol Imaging 41 : 1624-1634, 2014
5) Yang, J et al : PET Index of Bone Glucose Metabolism (PIBGM) Classification of PET/CT Data for Fever of Unknown Origin Diagnosis. PLoS One 10 : e0130173, 2015
6) Balink, H et al : 18F-FDG PET/CT in inflammation of unknown origin : a cost-effectiveness pilot-study. Eur J Nucl Med Mol Imaging 42 : 1408-1413, 2015
P.273 掲載の参考文献
1) Kim, S-J et al : Comparing the Diagnostic Accuracies of F-18 Fluorodeoxyglucose Positron Emission Tomography and Magnetic Resonance Imaging for the Detection of Spondylodiscitis : A Meta-analysis. Spine (Phila Pa 1976) 44 : E414-E422, 2019

XI リンパ節・リンパ管

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1) Williams, WH et al : Radionuclide lymphangioscintigraphy in the evaluation of peripheral lymphedema. Clin Nucl Med 25 : 451-464, 2000
2) Ogawa, Y et al : 99mTc-DTPA-HSA lymphoscintigraphy in lymphedema of the lower extremities : diagnostic significance of dynamic study and muscular exercise. Kaku Igaku 36 : 31-36, 1999

XII 内用療法

P.291 掲載の参考文献
1) 国立がん研究センター : がん情報サービス「がん登録・統計」, 2017
2) 全国がんセンター協議会 : 全がん協生存率調査 2010年~2012年全症例
3) 日本核医学会分科会 腫瘍・免疫核医学研究会 甲状腺RI治療委員会 : 放射性ヨウ素内用療法に関するガイドライン 第6版, 2018
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5) 日本医学放射線学会ほか : 残存甲状腺破壊を目的としたI-131 (1,110 MBq) による外来治療実施要綱 改訂第4版, 2018
6) Mazzaferri, EL et al : Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer. Am J Med 97 : 418-428, 1994
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3) 日本甲状腺学会 : バセドウ病131I内用療法の手引き, 2007
4) Valachis, A et al : High versus low radioiodine activity in patients with differentiated thyroid cancer : a meta-analysis. Acta Oncol 52 : 1055-1061, 2013
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1) 日本医学放射線学会ほか : 塩化ラジウム (Ra-223) 注射液を用いる内用療法の適正使用マニュアル第二版, 2019
1) 国立がん研究センター : がん情報サービス「がん登録・統計」, 2017
2) 全国がんセンター協議会 : 全がん協生存率調査 2010年~2012年
3) Parker, C et al : Alpha emitter radium-223 and survival in metastatic prostate cancer. N Engl J Med 369 : 213-223, 2013
4) Hoskin, P et al : Efficacy and safety of radium-223 dichloride in patients with castration-resistant prostate cancer and symptomatic bone metastases, with or without previous docetaxel use : a prespecified subgroup analysis from the randomised, double-blind, phase 3 ALSYMPCA trial. Lancet Oncol 15 : 1397-1406, 2014
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1) 国立がん研究センター : がん情報サービス「がん登録・統計」, 2017
1) 日本医学放射線学会ほか : イットリウム-90標識抗CD20抗体を用いた放射免疫療法の適正使用マニュアル 第3版, 2016
2) 全国がんセンター協議会 : 全がん協生存率調査 2010年~2012年全症例
3) Tobinai, K et al : Japanese phase II study of 90Y-ibritumomab tiuxetan in patients with relapsed or refractory indolent B-cell lymphoma. Cancer Sci 100 : 158-164, 2009
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1) Ito, T et al : Epidemiological trends of pancreatic and gastrointestinal neuroendocrine tumors in Japan : a nationwide survey analysis. J Gastroenterol 50 : 58-64, 2015
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4) 厚生労働省医政局地域医療計画課 : 医政地発0819 第1号 令和3年8月19日 放射性医薬品を投与された患者の退出等について, 2021
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2) 日本核医学会分科会 腫瘍・免疫核医学研究会 131I-MIBG 内照射療法検討委員会 : 神経内分泌腫瘍に対する131I-MIBG 内照射療法の適正使用ガイドライン案, 2014
3) Yoshinaga, K et al : Effects and safety of 131I-metaiodobenzylguanidine (MIBG) radiotherapy in malignant neuroendocrine tumors : results from a multicenter observational registry. Endocr J 61 : 1171-1180, 2014
4) Yoshinaga, K et al : Effects of Repeated 131I-meta-iodobenzylguanidine Radiotherapy on Tumor Size and Tumor Metabolic Activities in Patients with Metastatic Neuroendocrine Tumors. J Nucl Med 120 : 25083, 2020

XIII 核医学の今後の発展

P.313 掲載の参考文献
1) Hicks, RJ et al : FAPI PET/CT : Will It End the Hegemony of 18F-FDG in Oncology? J Nucl Med 62 : 296-302, 2021
2) Azargoshasb, S et al : Optical Navigation of a DROP-IN γ-Probe as a Means to Strengthen the Connection Between Robot-Assisted and Radioguided Surgery. J Nucl Med 62 : 1314-1317, 2021
3) Hirata, K et al : A Preliminary Study to Use SUVmax of FDG PET-CT as an Identifier of Lesion for Artificial Intelligence. Front Med (Lausanne) 8 : 647562, 2021

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