麻酔科学レビュー 2022

出版社: 総合医学社
著者:
発行日: 2022-06-25
分野: 臨床医学:外科  >  麻酔科学/ペイン
ISBN: 9784883787487
電子書籍版: 2022-06-25 (第1版第1刷)
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2020年8月~2021年7月の1年間に国内外で発表された論文・ガイドラインから、麻酔科学分野のエキスパート医師が主要な文献(約1200本)をピックアップし、レビューしています。 60テーマを取り上げており、この1冊を読むだけで、最新の研究成果や麻酔科学分野の動向を把握することが可能です。

目次

  • 1.麻酔前投薬と術前評価
    2.術前絶飲食
    3.周術期禁煙ガイドライン
    4.麻酔と気道管理・確保
    5.吸入麻酔薬
    6.悪性高熱症ガイドライン
    7.静脈麻酔薬(麻薬を除く)
    8.新しい全身麻酔薬レミマゾラム
    9.筋弛緩薬と拮抗薬
    10.局所麻酔薬
    11.心・血管作動薬
    12.麻酔に用いられる麻薬性鎮痛薬と鎮静薬
    13.麻酔と呼吸機能
    14.麻酔と心機能
    15.麻酔と冠循環
    16.麻酔と肝機能
    17.麻酔と腎機能
    18.麻酔と脳神経機能
    19.麻酔薬と臓器保護作用
    20.麻酔深度とモニター活用法
    21.麻酔領域での経食道心エコー(TEE)による評価
    22.超音波診断と末梢神経ブロック
    23.周術期ポイントオブケア超音波~ABCD sonography~
    24.輸血と輸液
    25.宗教的輸血拒否
    26.危機的出血への対応
    27.自己血輸血
    28.全静脈麻酔(TIVA),鎮静(MAC)
    29.手術室危機管理・安全対策
    30.WHO安全な手術のためのガイドライン
    31.硬膜外麻酔と脊髄くも膜下麻酔
    32.小児麻酔
    33.高齢者麻酔
    34.緊急手術の麻酔
    35.産科麻酔
    36.産科危機的出血への対応ガイドライン
    37.内視鏡・ロボット手術の麻酔
    38.日帰り手術の麻酔
    39.心臓・大血管手術の麻酔
    40.小児心臓手術の麻酔
    41.脳外科の麻酔
    42.Awake craniotomyの麻酔
    43.移植手術の麻酔
    44.抗血栓療法ガイドライン
    45.麻酔関連偶発症
    46.痛みの生理学
    47.術後の疼痛管理
    48.ペインクリニック
    49.緩和ケアとがんの痛みの治療
    50.麻酔科医と救急医療
    51.心肺蘇生と脳保護
    52.手術室の効率化と安全
    53.麻酔科領域の新機材,新技術,新知見
    54.新しい人工呼吸
    55.集中治療(1)呼吸・循環管理
    56.集中治療(2)体液,栄養,感染の管理
    57.集中治療(3)ICUにおける鎮痛と鎮静
    58.集中治療(4)ICUにおけるモニター
    59.集中治療(5)小児集中治療
    60.血液浄化療法

この書籍の参考文献

参考文献のリンクは、リンク先の都合等により正しく表示されない場合がありますので、あらかじめご了承下さい。

本参考文献は電子書籍掲載内容を元にしております。

1. 麻酔前投薬と術前評価

P.1 掲載の参考文献
1) Ohba T, Akaike H, Fujita K et al : Risk factors and assessment using an endoscopic scoring system for postoperative respiratory complications after anterior cervical decompression and fusion surgery. Spine Surg Relat Res 5 : 10-15, 2021
P.2 掲載の参考文献
2) Fujiwara K, Taira K, Donishi R et al : Preoperative predictors of dysphagia after transoral surgery. Int J Clin Oncol 26 : 835-840, 2021
P.3 掲載の参考文献
3) Jung MJ, Libaw JS, Ma K et al : Pediatric distraction on induction of anesthesia with virtual reality and perioperative anxiolysis : a randomized controlled trial. Anesth Analg 132 : 798-806, 2021

2. 術前絶飲食

P.5 掲載の参考文献
1) Brockel MA, Kenny MC, Sevick CJ et al : The role of preoperative instructions in parents' understanding of preoperative fasting for outpatient pediatric urology procedures. Pediatr Surg Int 36 : 1111-1116, 2020
P.7 掲載の参考文献
2) Simpao AF, Wu L, Nelson O et al : Preoperative fluid fasting times and postinduction low blood pressure in children : a retrospective analysis. Anesthesiology 133 : 523-533, 2020
P.8 掲載の参考文献
3) Marquini GV, da Silva Pinheiro FE, da Costa Vieira AU et al : Preoperative fasting abbreviation (Enhanced Recovery After Surgery protocol) and effects on the metabolism of patients undergoing gynecological surgeries under spinal anesthesia : a randomized clinical trial. Nutrition 77 : 110790, 2020

3. 周術期禁煙ガイドライン

P.9 掲載の参考文献
1) Kamarajah SK, Madhavan A, Chmelo J et al : Impact of smoking status on perioperative morbidity, mortality, and long-term survival following transthoracic esophagectomy for esophageal cancer. Ann Surg Oncol 28 : 4905-4915, 2021
2) Zucker I, Bouz A, Castro G et al : Smoking as a risk factor for surgical site complications in implant-based breast surgery. Cureus 13 : e18876, 2021
3) Nagoshi N, Kono H, Tsuji O et al : Impact of tobacco smoking on outcomes after posterior decompression surgery in patients with cervical spondylotic myelopathy : a retrospective multicenter study. Clin Spine Surg 33 : e493-e498, 2020
4) Senker W, Stefanits H, Gmeiner M et al : The influence of smoking in minimally invasive spinal fusion surgery. Open Med (Wars) 16 : 198-206, 2021
P.10 掲載の参考文献
5) Park H, de Virgilio C, Kim DY et al : Effects of smoking and different BMI cutoff points on surgical site infection after elective open ventral hernia repair. Hernia 25 : 337-343, 2021
6) Tang H, Hou J, Chen K et al : Association between smoking and in-hospital mortality in patients with left ventricular dysfunction undergoing coronary artery bypass surgery : a propensity-matched study. BMC Cardiovasc Disord 21 : 236, 2021
7) Liew LQ, Teo WW, Seet E et al : Factors predicting one-year post-surgical mortality amongst older Asian patients undergoing moderate to major non-cardiac surgery-a retrospective cohort study. BMC Surg 20 : 11, 2020
8) Ayazi K, Sayadi S, Hashemi M et al : Preoperative smoking cessation and its association with postoperative complications and length of hospital stay in patients undergoing herniorrhaphy. Tanaffos 20 : 59-63, 2021
9) Takenaka T, Shoji F, Tagawa T et al : Does short-term cessation of smoking before lung resections reduce the risk of complications? J Thorac Dis 12 : 7127-7134, 2020
10) Masoudkabir F, Yavari N, Pashang M et al : Smoking cessation after surgery and midterm outcomes of surgical revascularization. Ann Thorac Surg 109 : 1874-1879, 2020
11) Myoga Y, Manabe H, Osaki Y : The effects of preoperative alcohol, tobacco, and psychological stress on postoperative complications : a prospective observational study. BMC Anesthesiol 21 : 245, 2021
12) Kim CS, Sim JH, Kim Y et al : Association between postoperative opioid requirements and the duration of smoking cessation in male smokers after laparoscopic distal gastrectomy with gastroduodenostomy. Pain Res Manag 2021 : 1541748, 2021
P.11 掲載の参考文献
13) Nazir M, Afshan G, Ejaz M et al : Duration of cessation of smoking before elective surgery : Impact on intraoperative hemodynamics and early postoperative pain in developing country. Open J Anesthesiol 11 : 288-297, 2021
14) McCaffrey N, Scollo M, Dean E et al : What is the likely impact on surgical site infections in Australian hospitals if smoking rates are reduced? A cost analysis. PLoS One 16 : e0256424, 2021
15) Bloom JA, Asban A, Tian T et al : A costutility analysis comparing immediate oncoplastic surgery with delayed oncoplastic surgery in smoking breast cancer patients. Ann Surg Oncol 28 : 2579-2588, 2021
P.12 掲載の参考文献
16) Howard R, Singh K, Englesbe M : Prevalence and trends in smoking among surgical patients in Michigan, 2012-2019. JAMA Netw Open 4 : e210553, 2021
17) Wolvers PJD, Ayubi O, Bruin SC et al : Smoking behaviour and beliefs about smoking cessation after bariatric surgery. Obes Surg 31 : 239-249, 2021
18) Ampatzidou F, Ioannidis R, Drosos O et al : Smoking behavior after coronary artery bypass surgery : quit, relapse, continuing. Ann Card Anaesth 24 : 56-61, 2021
19) Mustoe MM, Clark JM, Huynh TT et al : Engagement and effectiveness of a smoking cessation quitline intervention in a thoracic surgery clinic. JAMA Surg 155 : 816-822, 2020
20) He Y, Tan M, Shi M et al : Smoking characteristics and readiness-to-quit status among smokers attending preoperative assessment clinic-a prospective cohort study. Risk Manag Healthc Policy 14 : 2483-2490, 2021
P.13 掲載の参考文献
21) Greenberg JA, Zwiep TM, Sadek J et al : Clinical practice guideline : evidence, recommendations and algorithm for the preoperative optimization of anemia, hyperglycemia and smoking. Can J Surg 64 : e491-e509, 2021
22) Melloul E, Lassen K, Roulin D et al : Guidelines for perioperative care for pancreatoduodenectomy : Enhanced Recovery After Surgery (ERAS) recommendations 2019. World J Surg 44 : 2056-2084, 2020
23) Debono B, Wainwright TW, Wang MY et al : Consensus statement for perioperative care in lumbar spinal fusion : Enhanced Recovery After Surgery (ERAS(R)) Society recommendations. Spine J 21 : 729-752, 2021
24) Hubner M, Kusamura S, Villeneuve L et al : Guidelines for perioperative care in cytoreductive surgery (CRS) with or without hyperthermic intraperitoneal chemotherapy (HIPEC) : enhanced recovery after surgery (ERAS(R)) society recommendations Part I : Preoperative and intraoperative management. Eur J Surg Oncol 46 : 2292-2310, 2020
25) Budacan AM, Mehdi R, Kerr AP et al : National survey of enhanced recovery after thoracic surgery practice in the United Kingdom and Ireland. J Cardiothorac Surg 15 : 95, 2020
P.14 掲載の参考文献
26) Rusy DA, Honkanen A, Landrigan-Ossar MF et al : Vaping and e-cigarette use in children and adolescents : implications on perioperative care from the American Society of Anesthesiologists Committee on Pediatric Anesthesia, Society for Pediatric Anesthesia, and American Academy of Pediatrics Section on Anesthesiology and Pain Medicine. Anesth Analg 133 : 562-568, 2021
27) Famiglietti A, Memoli JW, Khaitan PG : Are electronic cigarettes and vaping effective tools for smoking cessation? Limited evidence on surgical outcomes : a narrative review. J Thorac Dis 13 : 384-395, 2021

4. 麻酔と気道管理・確保

P.15 掲載の参考文献
1) Chrimes N, Higgs A, Law JA et al : Project for Universal Management of Airways-part 1 : concept and methods. Anaesthesia 75 : 1671-1682, 2020
2) Ahmad I, Smith AF : Principles for guidelines and guidelines for principles of universal airway management. Anaesthesia 75 : 1570-1573, 2020
3) Kornas RL, Owyang CG, Sakles JC et al : Evaluation and management of the physiologically difficult airway : consensus recommendations from society for airway management. Anesth Analg 132 : 395-405, 2021
P.16 掲載の参考文献
4) Cook TM, McGuire B, Mushambi M et al : Airway management guidance for the endemic phase of COVID-19. Anaesthesia 76 : 251-260, 2021
5) Saito T, Asai T : Aerosol containment device for airway management of patients with COVID-19 : a narrative review. J Anesth 35 : 384-389, 2021
6) Sorbello M, Rosenblatt W, Hofmeyr R et al : Aerosol boxes and barrier enclosures for airway management in COVID-19 patients : a scoping review and narrative synthesis. Br J Anaesth 125 : 880-894, 2020
7) Perella P, Tabarra M, Hataysal E et al : Minimising exposure to droplet and aerosolised pathogens : a computational fluid dynamics study. Br J Anaesth 126 : 544-549, 2021
8) Wong DJN, El-Boghdadly K, Owen R et al : Emergency airway management in patients with COVID-19 : a prospective international multicenter cohort study. Anesthesiology 135 : 292-303, 2021
9) Disma N, Virag K, Riva T et al : Difficult tracheal intubation in neonates and infants. NEonate and Children audiT of Anaesthesia pRactice IN Europe (NECTARINE) : a prospective European multicentre observational study. Br J Anaesth 126 : 1173-1181, 2021
10) Jagannathan N, Asai T : Difficult airway management : children are different from adults, and neonates are different from children! Br J Anaesth 126 : 1086-1088, 2021
P.17 掲載の参考文献
11) Brodsky MB, Akst LM, Jedlanek E et al : Laryngeal injury and upper airway symptoms after endotracheal intubation during surgery : a systematic review and meta-analysis. Anesth Analg 132 : 1023-1032, 2021
12) Heard A, Gordon H, Douglas S et al : Front-of-neck airway rescue with impalpable anatomy during a simulated cannot intubate, cannot oxygenate scenario : scalpel finger cannula versus scalpel finger bougie in a sheep model. Br J Anaesth 125 : 184-191, 2020
13) Asai T : Surgical cricothyrotomy, rather than percutaneous cricothyrotomy, in "cannot intubate, cannot oxygenate" situation. Anesthesiology 125 : 269-271, 2016
14) Laviola M, Niklas C, Das A et al : Ventilation strategies for front of neck airway rescue : an in silico study. Br J Anaesth 126 : 1226-1236, 2021
P.18 掲載の参考文献
16) Garcia-Marcinkiewicz AG, Adams HD, Gurnaney H et al : A retrospective analysis of neuromuscular blocking drug use and ventilation technique on complications in the pediatric difficult intubation registry using propensity score matching. Anesth Analg 131 : 469-479, 2020
18) Schaefer MS, Hammer M, Santer P et al : Succinylcholine and postoperative pulmonary complications : a retrospective cohort study using registry data from two hospital networks. Br J Anaesth 125 : 629-636, 2020
19) Li G, Freundlich RE, Gupta RK et al : Postoperative pulmonary complications' association with sugammadex versus neostigmine : a retrospective registry analysis. Anesthesiology 134 : 862-873, 2021
P.19 掲載の参考文献
20) Ledowski T, Szabo-Maak Z, Loh PS et al : Reversal of residual neuromuscular block with neostigmine or sugammadex and postoperative pulmonary complications : a prospective, randomised, double-blind trial in high-risk older patients. Br J Anaesth 127 : 316-323, 2021
21) Peyton J, Park R, Staffa SJ et al : A comparison of videolaryngoscopy using standard blades or non-standard blades in children in the Paediatric Difficult Intubation Registry. Br J Anaesth 126 : 331-339, 2021
22) Garcia-Marcinkiewicz AG, Kovatsis PG, Hunyady AI et al : First-attempt success rate of video laryngoscopy in small infants (VISI) : a multicentre, randomised controlled trial. Lancet 396 : 1905-1913, 2020
23) Singleton BN, Morris FK, Yet B et al : Effectiveness of intubation devices in patients with cervical spine immobilisation : a systematic review and network meta-analysis. Br J Anaesth 126 : 1055-1066, 2021
24) Hammer M, Santer P, Schaefer MS et al : Supraglottic airway device versus tracheal intubation and the risk of emergent postoperative intubation after general anaesthesia in adults : a retrospective cohort study. Br J Anaesth 126 : 738-745, 2021
P.20 掲載の参考文献
25) White LD, Thang C, Hodsdon A et al : Comparison of supraglottic airway devices with endotracheal intubation in low-risk patients for cesarean delivery : systematic review and meta-analysis. Anesth Analg 131 : 1092-1101, 2020
26) Stolady D, Laviola M, Pillai A et al : Effect of variable 26 pre-oxygenation endpoints on safe apnoea time using high flow nasal oxygen for women in labour : a modelling investigation. Br J Anaesth 126 : 889-895, 2021

5. 吸入麻酔薬

P.22 掲載の参考文献
1) Answine JF : Desflurane should not desappear. Anesth Analg 132 : e41-e42, 2021
2) Andersen MPS, Nielsen OJ, Sherman JD : The global warming potentials for anesthetic gas sevoflurane need significant corrections. Environ Sci Technol 55 : 10189-10191, 2021
3) Lopes R, Shelton C, Charlesworth M : Inhalational anaesthetics, ozone depletion, and greenhouse warming : the basics and status of our efforts in environmental mitigation. Curr Opin Anaesthesiol 34 : 415-420, 2021
4) Kostrubiak M, Vatovec CM, Dupigny-Giroux LA et al : Water pollution and environmental concerns in anesthesiology. J Med Syst 44 : 169, 2020
P.23 掲載の参考文献
5) Pin-On P, Leurcharusmee P, Tanasungnuchit S et al : Desflurane in not inferior to sevoflurane in the occurance of adverse respiratory events during laryngeal mask airway anesthesia : a non-inferiority randomized double-blinded controlled study. Minerva Anaestesiol 86 : 608-616, 2020
6) Huang PJ, Kang YN, Tsai PS et al : Noninferior of desflurane to sevoflurane in the occurrence of adverse respiratory events during laryngeal mask airway anesthesia in pediatrics. Minerva Anaestesiol 87 : 241-242, 2020
7) Zucco L, Santer P, Levy N et al : A comparison of postoperative respiratory complications associated with the use of desflurane and sevoflurane : a single-centre cohort study. Anaesthesia 76 : 36-44, 2020
8) Tabnak P, Masrouri S, Geraylow KR et al : Targeting miRNAs with anesthetics in ancer : current understanding and future perspectives. Biomed Pharmacother 144 : 112309, 2021
P.24 掲載の参考文献
9) Wang J, Cheng CS, Lu Y et al : Volatile anesthetics regulate anti-cancer relevant signaling. Front Oncol 11 : 610514, 2021
10) Ishikawa M, Iwasaki M, Zhao H et al : Sevoflurane and desflurane exposure enhanced cell proliferation and migration in ovarian cancer cells via miR-210 and miR-138 downregulation. Int J Mol Sci 22 : 1826, 2021
11) Ishikawa M, Iwasaki M, Zhao H et al : Inhalational anesthetics inhibit neuroblastoma cell proliferation and migration via miR-138, -210, and -335. Int J Mol Sci 22 : 4355, 2021
12) Chen H, Zhu XM, Luo ZL et al : Sevoflurane induction alleviates the progression of gastric cancer by upregulating the miR-34a/TGIF2 axis. Eur Rev Med Pharmacol Sci 24 : 11883-11890, 2020
13) Hu N, Duan JA, Yu Y et al : Sevoflurane inhibits the migration, invasion and induces apoptosis by regulating the expression of WNT1 via miR-637 in colorectal cancer. Anticancer Drugs 32 : 537-547, 2021
P.25 掲載の参考文献
14) Deng X, Vipani M, Liang G et al : Sevoflurane modulates breast cancer cell survival via modulation of intracellular calcium. BMC Anesthesiol 20 : 253, 2020
15) Zhang W, Sheng B, Chen S et al : Sevoflurane enhances proliferation, metastatic potential of cervical cancer cells via the histone deacetylase 6 modulation in vitro. Anesthesiology 132 : 1469-1481, 2020
16) Raub D, Platzbecker K, Grabitz SD et al : Effects of volatile anesthetics on postoperative ischemic stroke incidence. J Am Heart Assoc 10 : e018952, 2021
P.26 掲載の参考文献
17) Ngamsri KC, Fabian F, Fuhr A et al : Sevoflurane exerts protective effects in murine peritonitis-induced sepsis via hypoxia-inducible factor 1α/adenosine A2B receptor signaling. Anesthesiology 135 : 136-150, 2021
18) Zhang EF, Zhao X, Ma H et al : A subanesthetic dose of sevoflurane combined with oxygen exerts bactericidal effects and prevents lung injury through the nitric oxide pathway during sepsis. Biomed Pharmacother 127 : 110169, 2020
19) Zhong M, Che L, Du M et al : Desflurane protects against liver ischemia/reperfusion injury via regulating miR-135b-5p. J Chin Med Assoc 84 : 38-45, 2021
P.27 掲載の参考文献
20) Koraki E, Mantzoros I, Chatzakis C et al : Metalloproteinase expression after desflurane preconditioning in hepatectomies : a randomized clinical trial. World J Hepatol 12 : 1098-1114, 2020
21) Shi CX, Jin J, Wang XQ et al : Sevoflurane attenuates brain damage through inhibiting autophagy and apoptosis in cerebral ischemia-reperfusion rats. Mol Med Rep 21 : 123-130, 2019
P.28 掲載の参考文献
22) Hughes CG, Boncyk CS, Culley DJ et al : American Society for Enhanced Recovery and Perioperative Quality Initiative joint consensus statement on postoperative delirium prevention. Anesth Analg 130 : 1572-1590, 2020
23) Amado LA, Perrie H, Scribante J et al : Preoperative cognitive dysfunction in older elective noncardiac surgical patients in South Africa. Br J Anaesth 125 : 275-281, 2020
24) Gkliatis E, Makris A, Staikou C : The impact of inhalation anesthetics on early postoperative cognitive function and recovery characteristics in Down syndrome patients : a randomized, double-blind study. BMC Anesthesiol 21 : 227, 2021
25) Han F, Zhao J, Zhao G : Prolonged volatile anesthetic exposure exacerbates cognitive impairment and neuropathology in the 5xFAD mouse model of Alzheimer's disease. J Alzheimers Dis 84 : 1551-1562, 2021
P.29 掲載の参考文献
26) Imai R, Makino H, Katoh T et al : Desflurane anesthesia shifts the circadian rhythm phase depending on the time of day of anesthesia. Sci Rep 10 : 18273, 2020

6. 悪性高熱症ガイドライン

P.30 掲載の参考文献
1) Ruffert H, Bastian B, Bendixen D et al : Consensus guidelines on perioperative management of malignant hyperthermia suspected or susceptible patients from the European Malignant Hyperthermia Group. Br J Anaesth 126 : 120-130, 2021
2) Hopkins PM, Girard T, Dalay S et al : Malignant hyperthermia 2020 : Guideline from the Association of Anaesthetists. Anaesthesia 76 : 655-664, 2021
3) Biesecker LG, Dirksen RT, Girard T et al : Genomic Screening for Malignant Hyperthermia Susceptibility. Anesthesiology 133 : 1277-1282, 2020
4) Hoppe K, Jurkat-Rott K, Kranepuhl S et al : Relevance of pathogenicity prediction tools in human RYR1 variants of unknown significance. Sci Rep 11 : 3445, 2021
P.31 掲載の参考文献
5) Fridriksdottir R, Jonsson AJ, Jensson BO et al : Sequence variants in malignant hyperthermia genes in Iceland : classification and actionable findings in a population database. Eur J Hum Genet 29 : 1819-1824, 2021
6) Ibarra Moreno CA, Kraeva N, Zvaritch E et al : A multi-dimensional analysis of genotype-phenotype discordance in malignant hyperthermia susceptibility. Br J Anaesth 125 : 995-1001, 2020
7) van den Bersselaar LR, Greven T, Bulger T et al : RYR1 variant c.38T > G, p.Leu13Arg causes hypersensitivity of the ryanodine receptor-1 and is pathogenic for malignant hyperthermia. Br J Anaesth 127 : e63-e65, 2021
8) Johnston JJ, Dirksen RT, Girard T et al : Variant curation expert panel recommendations for RYR1 pathogenicity classifications in malignant hyperthermia susceptibility. Genet Med 23 : 1288-1295, 2021
P.32 掲載の参考文献
9) Bojko B, Vasiljevic T, Boyaci E et al : Untargeted metabolomics profiling of skeletal muscle samples from malignant hyperthermia susceptible patients. Can J Anaesth 68 : 761-772, 2021
10) Chang L, Liu X, Diggle CP et al : Bioenergetic defects in muscle fibers of RYR1 mutant knock-in mice associated with malignant hyperthermia. J Biol Chem 295 : 15226-15235, 2020
11) Gonzalez A, Girard T, Dell-Kuster S et al : BMI and malignant hyperthermia pathogenic ryanodine receptor type 1 sequence variants in Switzerland : A retrospective cohort analysis. Eur J Anaesthesiol 38 : 751-757, 2021
12) Wang HJ, Lee CS, Yee RSZ et al : Adaptive thermogenesis enhances the life-threatening response to heat in mice with an Ryr1 mutation. Nat Commun 11 : 5099, 2020
13) Lopez JR, Uryash A, Adams J et al : Molecular modification of transient receptor potential canonical 6 channels modulates calcium dyshomeostasis in a mouse model relevant to malignant hyperthermia. Anesthesiology 134 : 234-247, 2021
14) Yamazawa T, Kobayashi T, Kurebayashi N et al : A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke. Nat Commun 12 : 4293, 2021
P.33 掲載の参考文献
15) Wei H, Liang G, Vera RM : Dantrolene repurposed to treat sepsis or septic shock and COVID-19 patients. Eur Rev Med Pharmacol Sci 25 : 3136-3144, 2021
16) Chiba N, Matsuzaki M, Mawatari T et al : Beneficial effects of dantrolene in the treatment of rhabdomyolysis as a potential late complication associated with COVID-19 : a case report. Eur J Med Res 26 : 18, 2021
P.34 掲載の参考文献
17) Watanabe T, Miyoshi H, Noda Y et al : Effects of remimazolam and propofol on Ca2+ regulation by ryanodine receptor 1 with malignant hyperthermia mutation. Biomed Res Int 2021 : 8845129, 2021
18) Gonzalez A, Iles TL, Iaizzo PA et al : Impact of statin intake on malignant hyperthermia : an in vitro and in vivo swine study. BMC Anesthesiol 20 : 270, 2020
19) Haseeb M, Thompson PD : The effect of statins on RyR and RyR-associated disease. J Appl Physiol (1985) 131 : 661-671, 2021
P.35 掲載の参考文献
20) Maryansky A, Rose JC, Rosenblatt MA et al : Postoperative hyperthermia and hemodynamic instability in a suspected malignant hyperthermia-susceptible patient : a case report. AA Pract 15 : e01314, 2021
21) Tsutsumi YM, Kakuta N, Kawanishi R et al : Malignant hyperthermia in a 16-dayold infant with congenital diaphragmatic hernia : a case report. J Anesth 35 : 311-314, 2021
22) Yoo SW, Baek SJ, Kim DC et al : A case report of malignant hyperthermia in a patient with myotonic dystrophy type I : a CARE-compliant article. Medicine (Baltimore) 100 : e25859, 2021
23) Yang L, Dedkova EN, Allen PD et al : T lymphocytes from malignant hyperthermia-susceptible mice display aberrations in intracellular calcium signaling and mitochondrial function. Cell Calcium 93 : 102325, 2021

7. 静脈麻酔薬 ( 麻薬を除く )

P.36 掲載の参考文献
P.37 掲載の参考文献
2) Nagata O, Matsuki Y, Ogino Y et al : Safety and efficacy of an automated anesthesia delivery system for total intravenous anesthesia with propofol, remifentanil, and rocuronium : a non-inferiority randomized controlled trial versus manually controlled anesthesia. J Anesth 36 : 96-106, 2021
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6) Deguchi H, Furutani K, Mitsuma Y et al : Propofol reduces the amplitude of transcranial electrical motor-evoked potential without affecting spinal motor neurons : a prospective, single-arm, interventional study. J Anesth 35 : 434-441, 2021
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9) Chang CY, Wu MY, Chien YJ et al : Anesthesia and long-term oncological outcomes : a systematic review and meta-analysis. Anesth Analg 132 : 623-634,2021
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16) Kamp J, van Velzen M, Aarts L et al : Stereoselective ketamine effect on cardiac output : a population pharmacokinetic/pharmacodynamic modelling study in healthy volunteers. Br J Anaesth 127 : 23-31, 2021
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8. 新しい全身麻酔薬レミマゾラム

P.42 掲載の参考文献
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5) Ibrahim AE, Taraday JK, Kharasch ED : Bispectral index monitoring during sedation with sevoflurane, midazolam, and propofol. Anesthesiology 95 : 1151-1159, 2001
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9) Zhou J, Curd L, Lohmer LL et al : Population pharmacokinetics of remimazolam in procedural sedation with nonhomogeneously mixed arterial and venous concentrations. Clin Transl Sci 14 : 326-334, 2020
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11) Pesic M, Stohr T, Ossig J et al : Remimazolam has low oral bioavailability and no potential for misuse in drug-facilitated sexual assaults, with or without alcohol : results from two randomised clinical trials. Drugs R D 20 : 267-277, 2020
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16) Sato T, Kato Y, Yamamoto M et al : Novel anesthetic agent remimazolam as an alternative for the asleep-awake-asleep technique of awake craniotomy. JA Clin Rep 6 : 92, 2020
17) Yoshida A, Kurata S, Kida K et al : Anesthetic management for the sleep-awake-sleep technique of awake craniotomy using a novel benzodiazepine remimazolam and its antagonist flumazenil. JA Clin Rep 7 : 14, 2021
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20) Matsuo M, Okada K, Onuki Y et al : Incompatibility of remimazolam besylate with Ringer's acetate infusion resulting in total occlusion of an intravenous catheter. BMJ Case Rep 14 : e241622, 2021
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9. 筋弛緩薬と拮抗薬

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1) Bruintjes MH, van Helden EV, Braat AE et al : Deep neuromuscular block to optimize surgical space conditions during laparoscopic surgery : a systematic review and meta-analysis. Br J Anaesth 118 : 834-842, 2017
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4) Oh CS, Lim HY, Jeon HJ et al : Effect of deep neuromuscular blockade on serum cytokines and postoperative delirium in elderly patients undergoing total hip replacement : a prospective single-blind randomized controlled trial. Eur J Anaesthesiol 38 (Suppl 1) : S58-S66, 2021
5) Lee BJ, Lee HN, Chung JY et al : Effect of deep versus moderate neuromuscular blockade on quantitatively assessed postoperative atelectasis using computed tomography in thoracic surgery ; a randomized double-blind controlled trial. J Clin Med 10 : 3228, 2021
6) Ziatkowski-Michaud J, Mazard T, Delignette MC et al : Neuromuscular monitoring and neuromuscular blocking agent shortages when treating crinically ill COVID-19 patients : a multicenter retrospective analysis. Br J Anaesth 127 : e73-e75, 2021
7) Weber V, Abbott TEF, Ackland GL : Reducing the dose of neuromuscular blocking agents with adjuncts : a systematic review and meta-analysis. Br J Anaesth 126 : 608-621, 2021
8) Takagi S, Kitajima O, Yamamoto M et al : Potentiation by sevoflurane of rocuronium-induced neuromuscular block is greater in older than younger adult patients : a randomized controlled trial. Br J Anaesth 125 : e351-353, 2020
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9) Zhao Y, Chen S, Huai X et al : Efficiency and safety of the selective relaxant binding agent adamgammadex sodium for reversing rocuronium-induced deep neuromuscular block : a single-center, openlabel, dose-finding, and phase IIa study. Front Med (Lausanne) 8 : 697395, 2021
10) Rudolph MI, Ng PY, Deng H et al : Comparison of a novel clinical score to estimate the risk of Residual neuromuscular block Prediction Score and the last train-of-four count documented in the electronic anaesthesia record : a retrospective cohort study of electronic data on file. Eur J Anaesthesiol 35 : 883-892, 2018
11) Patrocinio MD, Shay D, Rudolph MI et al : REsidual neuromuscular block prediction score versus train-of-four ratio and respiratory outcomes : a retrospective cohort study. Anesth Analg 133 : 610-619, 2021
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12) Nemes R, Lengyel S, Nagy G et al : Ipsilateral and simultaneous comparison of responses from acceleromyography- and electromyography-based neuromuscular monitors. Anesthesiology 135 : 597-611, 2021
13) Takagi S, Suzuki T, Nakatsuka H et al : Comparison of a new EMG module, AF-201P, with acceleromyography using the post-tetanic counts during rocuronium-induced deep neuromuscular block : a prospective, multicenter study. J Clin Monit Comput, 2021 doi : 10.1007/s10877-021-00768-z [online ahead of print]
14) Murphy GS, Szokol JW, Avram MJ et al : Comparison of the TOFscan and the TOF-Watch SX during recovery of neuromuscular function. Anesthesiology 129 : 880-888, 2018
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15) Renew JR, Hernandez-Torres V, Logvinov I et al : Comparison of the TetraGraph and TOFscan for monitoring recovery from neuromuscular blockade in the Post Anesthesia Care Unit. J Clin Anesth 71 : 110234, 2021
16) Schiavoni L, Pascarella G, Grande S et al : Neuromuscular block monitoring by smart-phone application (i-TOF(C) system) : an observational pilot study. NPJ Digit Med 3 : 137, 2020
17) Renew JR, Hex K, Johnson P et al : Ease of application of various neuromuscular devices for routine monitoring. Anesth Analg 132 : 1421-1428, 2021

10. 局所麻酔薬

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1) Ji T, Li Y, Deng X et al : Delivery of local anaesthetics by a self-assembled supramolecular system mimicking their interactions with a sodium channel. Nat Biomed Eng 5 : 1099-1109, 2021
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4) Finnerty DT, Buggy DJ : A novel role for lidocaine in COVID-19 patients? Br J Anaesth 125 : e391-e394, 2020
5) Galos EV, Tat TF, Popa R et al : Neutrophil extracellular trapping and angiogenesis biomarkers after intravenous or inhalation anaesthesia with or without intravenous lidocaine for breast cancer surgery : a prospective, randomised trial. Br J Anaesth 125 : 712-721, 2020
6) Uta D, Koga K, Furue H et al : L-bupivacaine inhibition of nociceptive transmission in rat peripheral and dorsal horn neurons. Anesthesiology 134 : 88-102, 2021
7) Miyoshi H, Kato T, Nakamura R et al : Pharmacokinetics of intraperitoneal and subcutaneous levobupivacaine in anesthetized rats. J Anesth 35 : 168-174, 2021
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8) Hino H, Matsuura T, Kuno M et al : Left ventricular hypertrophy increases susceptibility to bupivacaine-induced cardiotoxicity through overexpression of transient receptor potential canonical channels in rats. Anesthesiology 133 : 1077-1092, 2020
9) Santos GFS, Ferreira LO, Gerrits Mattos B et al : Electrocorticographic description of the effects of anticonvulsant drugs used to treat lidocaine-induced seizures. Brain Behav 11 : e01940, 2021
10) Liu Y, Zhang J, Yu P et al : Mechanisms and efficacy of intravenous lipid emulsion treatment for systemic toxicity from local anesthetics. Front Med (Lausanne) 8 : 756866, 2021
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11) Macfarlane AJR, Gitman M, Bornstein KJ et al : Updates in our understanding of local anaesthetic systemic toxicity : a narrative review. Anaesthesia 76 Suppl 1 : 27-39, 2021
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11. 心・血管作動薬

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2) Koch KU, Mikkelsen IK, Espelund US et al : Cerebral macro- and microcirculation during ephedrine versus phenylephrine treatment in anesthetized brain tumor patients : a randomized clinical trial using magnetic resonance imaging. Anesthesiology 135 : 788-803, 2021
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4) Akkermans A, van Waes JAR, van Doormaal TPC et al : Effects of dobutamine and phenylephrine on cerebral perfusion in patients undergoing cerebral bypass surgery : a randomised crossover trial. Br J Anaesth 125 : 539-547, 2020
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12) Theodoraki K, Hadzilia S, Valsamidis D et al : Prevention of hypotension during elective cesarean section with a fixed-rate norepinephrine infusion versus a fixedrate phenylephrine infusion. A double-blinded randomized controlled trial. Int J Surg 84 : 41-49, 2020
13) Ngan Kee WD, Lee SWY, Ng FF et al : Norepinephrine or phenylephrine during spinal anaesthesia for Caesarean delivery : a randomised double-blind pragmatic non-inferiority study of neonatal outcome. Br J Anaesth 125 : 588-595, 2020
14) Mostafa M, Hasanin A, Mostafa M et al : Hemodynamic effects norepinephrine versus phenylephrine infusion for prophylaxis against spinal anesthesia-induced hypotension in the elderly population undergoing hip fracture surgery : a randomized controlled trial. Korean J Anesthesiol 74 : 308-316, 2020
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15) Tholen M, Ricksten SE, Lannemyr L : Effects of levosimendan on renal blood flow and glomerular filtration in patients with acute kidney injury after cardiac surgery : a double blind, randomized placebo-controlled study. Crit Care 25 : 207, 2021
16) Kaddoura R, Omar A, Ibrahim MIM et al : The effectiveness of levosimendan on veno-arterial extracorporeal membrane oxygenation management and outcome : a systemic review and meta-analysis. J Cardiothorac Vasc Anesth 35 : 2483-2495, 2021
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12. 麻酔に用いられる麻薬性鎮痛薬と鎮静薬

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4) Chia PA, Cannesson M, Bui CCM : Opioid free anesthesia : feasible? Curr Opin Anaesthesiol 33 : 512-517, 2020
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7) Shanthanna H, Ladha KS, Kehlet H et al : Perioperative opioid administration. Anesthesiology 134 : 645-659, 2021
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9) Franz AM, Dahl JP, Huang H et al : The development of an opioid sparing anesthesia protocol for pediatric ambulatory tonsillectomy and adenotonsillectomy surgery-a quality improvement project. Paediatr Anaesth 29 : 682-689, 2019
10) Devine G, Cheng M, Martinez G et al : Opioid-free anesthesia for lung cancer resection : a case-control study. J Cardiothorac Vasc Anesth 34 : 3036-3040, 2020
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12) Grant MC, Isada T, Ruzankin P et al : Opioid-sparing cardiac anesthesia : secondary analysis of an Enhanced Recovery Program for cardiac surgery. Anesth Analg 131 : 1852-1861, 2020

13. 麻酔と呼吸機能

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5) Schjorring OL, Klitgaard TL, Perner A et al ; HOT-ICU Investigators : Lower or higher oxygenation targets for acute hypoxemic respiratory failure. N Engl J Med 384 : 1301-1311, 2021
6) Jiang Q, Kurz A, Zhang X et al : Supplemental intraoperative oxygen and long-term mortality : subanalysis of a multiple crossover cluster trial. Anesthesiology 134 : 709-721, 2021
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7) Ashley SL, Sjoding MW, Popova AP et al : Lung and gut microbiota are altered by hyperoxia and contribute to oxygen-induced lung injury in mice. Sci Transl Med 12 : eaau9959, 2020
8) Tharp WG, Murphy S, Breidenstein MW et al : Body habitus and dynamic surgical conditions independently impair pulmonary mechanics during robotic-assisted laparoscopic surgery. Anesthesiology 133 : 750-763, 2020
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9) Bao X, Vidal Melo MF : Lung mechanics of the obese undergoing robotic surgery and the pursuit of protective ventilation. Anesthesiology 133 : 695-697, 2020
10) Lagier D, Velly LJ, Guinard B et al : Perioperative open-lung approach, regional ventilation, and lung injury in cardiac surgery. Anesthesiology 133 : 1029-1045, 2020
11) Young CC, Harris EM, Vacchiano C et al : Lung-protective ventilation for the surgical patient : international expert panel-based consensus recommendations. Br J Anaesth 123 : 898-913, 2019
12) de Abreu MG, Schultz MJ, Neto AS et al : Open-lung ventilation strategy during general anesthesia : what happens intraoperatively stays intraoperatively. Anesthesiology 133 : 982-984, 2020
13) Karalapillai D, Weinberg L, Peyton P et al : Effect of intraoperative low tidal volume vs conventional tidal volume on postoperative pulmonary complications in patients undergoing major surgery : a randomized clinical trial. JAMA 324 : 848-858, 2020

14. 麻酔と心機能

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3) Ackland GL, Abbott TEF, Jones TF et al : Early elevation in plasma high-sensitivity troponin T and morbidity after elective noncardiac surgery : prospective multicentre observational cohort study. Br J Anaesth 124 : 535-543, 2020
4) Lee SH, Yang K, Park J et al : Association between high body mass index and mortality following myocardial injury after noncardiac surgery. Anesth Analg 132 : 960-968, 2021
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5) Fukuoka S, Kurita T, Dohi K et al : Untangling the obesity paradox in patients with acute myocardial infarction after primary percutaneous coronary intervention (detail analysis by age). Int J Cardiol 289 : 12-18, 2019
6) Kwon JH, Park J, Lee SH et al : Preoperative anaemia and myocardial injury after noncardiac surgery : A retrospective study. Eur J Anaesthesiol 38 : 582-590, 2021
7) Turan A, Leung S, Bajracharya GR et al : Acute postoperative pain is associated with myocardial injury after noncardiac surgery. Anesth Analg 131 : 822-829, 2020
8) Hatib F, Jian Z, Buddi S et al : Machinelearning algorithm to predict hypotension based on high-fidelity arterial pressure waveform analysis. Anesthesiology 129 : 663-674, 2018
9) Grundmann CD, Wischermann JM, Fassbender P et al : Hemodynamic monitoring with hypotension prediction index versus arterial waveform analysis alone and incidence of perioperative hypotension. Acta Anaesthesiol Scand 65 : 1404-1412, 2021
10) Maheshwari K, Shimada T, Yang D et al : Hypotension prediction index for prevention of hypotension during moderate- to high-risk noncardiac surgery. Anesthesiology 133 : 1214-1222, 2020
11) Schenk J, Wijnberge M, Maaskant JM et al : Effect of hypotension prediction indexguided intraoperative haemodynamic care on depth and duration of postoperativehypotension : a sub-study of the hypotension prediction trial. Br J Anaesth 127 : 681-688, 2021
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12) Kouz K, Hoppe P, Reese P et al : Relationship between intraoperative and preoperative ambulatory nighttime heart rates : a secondary analysis of a prospective observational study. Anesth Analg 133 : 406-412, 2021
13) Agerskov M, Thusholdt ANW, Holm-Sorensen H et al : Association of the intraoperative peripheral perfusion index with postoperative morbidity and mortality in acute surgical patients : a retrospective observational multicentre cohort study. Br J Anaesth 127 : 396-404, 2021
14) Ryu KH, Hwang SH, Shim JG et al : Comparison of vasodilatory properties between desflurane and sevoflurane using perfusion index : a randomized controlled trial. Br J Anaesth 125 : 935-942, 2020

15. 麻酔と冠循環

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2) Buxton BF, Hayward PA, Raman J et al : Long-term results of the RAPCO trials. Circulation 142 : 1330-1338, 2020
3) Lamy A, Browne A, Sheth T et al : Skeletonized vs pedicled internal mammary artery graft harvesting in coronary artery bypass surgery : a post hoc analysis from the COMPASS trial. JAMA Cardiol 6 : 1-8, 2021
4) Metkus TS, Thibault D, Grant MC et al : Transesophageal echocardiography in patients undergoing coronary artery bypass graft surgery. J Am Coll Cardiol 78 : 112-122, 2021
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5) Gaudino M, Sandner S, Di Giammarco G et al : The use of intraoperative transit time flow measurement for coronary artery bypass surgery : systematic review of the evidence and expert opinion statements. Circulation 144 : 1160-1171, 2021
6) Panza JA, Chrzanowski L, Bonow RO : Myocardial viability assessment before surgical revascularization in ischemic cardiomyopathy : JACC review topic of the week. J Am Coll Cardiol 78 : 1068-1077, 2021
7) Takahashi K, Serruys PW, Gao C et al : Ten-year all-cause death according to completeness of revascularization in patients with three-vessel disease or left main coronary artery disease : insights from the SYNTAX extended survival study. Circulation 144 : 96-109, 2021
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8) Reynolds HR, Shaw LJ, Min JK et al : Outcomes in the ISCHEMIA trial based on coronary artery disease and ischemia severity. Circulation 144 : 1024-1038, 2021
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12) Ronco D, Matteucci M, Ravaux JM et al : Mechanical circulatory support as a bridge to definitive treatment in post-infarction ventricular septal rupture. JACC Cardiovasc Interv 14 : 1053-1066, 2021
13) Napp LC, Cammann VL, Jaguszewski M et al : Coexistence and outcome of coronary artery disease in Takotsubo syndrome. Eur Heart J 41 : 3255-3268, 2020
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16) Valgimigli M, Cao D, Angiolillo DJ et al : Duration of dual antiplatelet therapy for patients at high bleeding risk undergoing PCI. J Am Coll Cardiol 78 : 2060-2072, 2021
17) Baber U, Dangas G, Angiolillo DJ et al : Ticagrelor alone vs. ticagrelor plus aspirin following percutaneous coronary intervention in patients with non-ST-segment elevation acute coronary syndromes : TWILIGHT-ACS. Eur Heart J 41 : 3533-3545, 2020
18) Koo BK, Kang J, Park KW et al : Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention (HOST-EXAM) : an investigator-initiated, prospective, randomised, open-label, multicentre trial. Lancet 397 : 2487-2496, 2021
19) Kogame N, Guimaraes PO, Modolo R et al : Aspirin-free prasugrel monotherapy following coronary artery stenting in patients with stable CAD : The ASET Pilot Study. JACC Cardiovasc Interv 13 : 2251-2262, 2020

16. 麻酔と肝機能

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1) El Aidouni G, Merbouh M, Lazreg M et al : Severe hepatic impairment after sevoflurane anesthesia in a 10-month-old child : case report. Ann Med Surg 70 : 102915, 2021
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17. 麻酔と腎機能

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18. 麻酔と脳神経機能

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19. 麻酔薬と臓器保護作用

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20. 麻酔深度とモニター活用法

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21. 麻酔領域での経食道心エコー ( TEE ) による評価

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22. 超音波診断と末梢神経ブロック

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12) Polshin V, Petro J, Wachtendorf LJ et al : Effect of peripheral nerve blocks on postanesthesia care unit length of stay in patients undergoing ambulatory surgery : a retrospective cohort study. Reg Anesth Pain Med 46 : 233-239, 2021

23. 周術期ポイントオブケア超音波~ABCD sonography~

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7) Delamarre L, Srairi M, Bouvet L et al : Anaesthesiologists' clinical judgment accuracy regarding preoperative full stomach : Diagnostic study in urgent surgical adult patients. Anaesth Crit Care Pain Med 40 : 100836, 2021
8) Moake MM, Jackson BF, Presley BC : Point-of-care ultrasound to assess gastric content. Pediatr Emerg Care 36 : 404-410, 2020
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24. 輸血と輸液

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19) Obradovic M, Kurz A, Kabon B et al : The effect of intraoperative goal-directed crystalloid versus colloid administration on perioperative inflammatory markers-a substudy of a randomized controlled trial. BMC Anesthesiol 20 : 210, 2020

25. 宗教的輸血拒否

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14) Carvalho Fiel D, Nunes Ficher K, Bernardi Taddeo J et al : Is there sufficient evidence justifying limited access of Jehovah's Witness patients to kidney transplantation? Transplantation 105 : 249-254, 2021
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26. 危機的出血への対応

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27. 自己血輸血

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24) Midorikawa Y, Saito J, Kitayama M et al : Intra-operative intravascular effect of the difference in colloid solutions during acute normovolemic hemodilution. JA Clin Rep 7 : 70, 2021

28. 全静脈麻酔 ( TIVA ), 鎮静 ( MAC )

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4) Shui M, Xue Z, Miao X et al : Intravenous versus inhalational maintenance of anesthesia for quality of recovery in adult patients undergoing non-cardiac surgery : a systematic review with meta-analysis and trial sequential analysis. PLoS One 16 : e0254271, 2021
5) Chang CY, Wu MY, Chien YJ et al : Anesthesia and long-term oncological outcomes : a systematic review and meta-analysis. Anesth Analg 132 : 623-634, 2021
6) Andereggen L, Zinn PO, Luedi MM : Anesthesia-related oncological outcomes : beyond volatiles and total intravenous anesthesia. Anesth Analg 132 : e119-e120, 2021
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14) Matsuki Y, Nagata O, Ogino Y et al : Impact of aging on interactions between opioid and propofol concentrations during total intravenous anesthesia. J Clin Anesth 71 : 110245, 2021
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16) Kim S, Chang BA, Rahman A et al : Analysis of urgent/emergent conversions from monitored anesthesia care to general anesthesia with airway instrumentation. BMC Anesthesiol 21 : 183, 2021
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18) Musuku SR, Capua CAD, Doshi I et al : Outcomes of transfemoral transcatheter aortic valve replacement performed with general anesthesia using a supraglottic airway versus monitored anesthesia care. J Cardiothorac Vasc Anesth 35 : 1760-1768, 2020

29. 手術室危機管理・安全対策

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14) Frane N, Megas A, Stapleton E et al : Radiation exposure in orthopaedics. JBJS Rev 8 : e0060, 2020

30. WHO 安全な手術のためのガイドライン

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31. 硬膜外麻酔と脊髄くも膜下麻酔

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32. 小児麻酔

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33. 高齢者麻酔

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34. 緊急手術の麻酔

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35. 産科麻酔

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36. 産科危機的出血への対応ガイドライン

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37. 内視鏡・ロボット手術の麻酔

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38. 日帰り手術の麻酔

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39. 心臓・大血管手術の麻酔

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13) Zhang Y, Gong H, Zhan B et al : Effects of bilateral Pecto-intercostal Fascial Block for perioperative pain management in patients undergoing open cardiac surgery : a prospective randomized study. BMC Anesthesiol 21 : 175, 2021
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40. 小児心臓手術の麻酔

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4) Long JB, Engorn BM, Hill KD et al : Postoperative hematocrit and adverse outcomes in pediatric cardiac surgery patients : a cross-sectional study from the Society of Thoracic Surgeons and Congenital Cardiac Anesthesia Society Database collaboration. Anesth Analg 133 : 1077-1088, 2021
5) Alten JA, Cooper DS, Blinder JJ et al : Epidemiology of acute kidney injury after neonatal cardiac surgery : a report from the multicenter neonatal and pediatric heart and renal outcomes network. Crit Care Med 49 : e941-e951, 2021
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10) Atasever AG, Eerans M, Van den Eynde R et al : Efficacy and safety of aprotinin in paediatric cardiac surgery : a systematic review and meta-analysis. Eur J Anaesthesiol 39 : 352-367, 2022
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11) Cortes RG, Villaescusa JU, Garcia MJS et al : Microcirculatory changes in pediatric patients during congenital heart defect corrective surgery. J Cardiovasc Transl Res 14 : 1173-1185, 2021
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13) Cruz-Beltran S, Lane A, Seth S et al : Antibodies to human leukocyte antigens and their association with blood product exposures in pediatric patients undergoing cardiac transplantation. Paediatr Anaesth 31 : 1065-1073, 2021
14) Liu Y, Luo Q, Su Z et al : Suppression of myocardial hypoxia-inducible factor-1α compromises metabolic adaptation and impairs cardiac function in patients with cyanotic congenital heart disease during puberty. Circulation 143 : 2254-2272, 2021
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16) Berger JA, Huh DD, Lee T et al : Perioperative management and consideration in pediatric patients with connective tissue disorders undergoing cardiac surgery. Paediatr Anaesth 31 : 820-826, 2021

41. 脳外科の麻酔

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3) Rerkasem A, Orrapin S, Howard DP et al : Local versus general anaesthesia for carotid endarterectomy. Cochrane Database Syst Rev 10 : CD000126, 2021
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5) Yu B, Peng Y, Qia H et al : The application of regional cerebral oxygenation monitoring in the prediction of cerebral hypoperfusion during carotid endarterectomy. J Neurosurg Anesthesiol 34 : 29-34, 2022
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42. Awake craniotomy の麻酔

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43. 移植手術の麻酔

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4) Kolodzie K, Cakmakkaya OS, Boparai ES et al : Perioperative normal saline administration and delayed graft function in patients undergoing kidney transplantation : a retrospective cohort study. Anesthesiology, 135 : 621-632, 2021
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5) van Rijn R, Schurink IJ, de Vries Y et al : Hypothermic machine perfusion in liver transplantation-a randomized trial. N Engl J Med 384 : 1391-1401, 2021

44. 抗血栓療法ガイドライン

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45. 麻酔関連偶発症

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46. 痛みの生理学

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47. 術後の疼痛管理

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48. ペインクリニック

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49. 緩和ケアとがんの痛みの治療

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50. 麻酔科医と救急医療

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51. 心肺蘇生と脳保護

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52. 手術室の効率化と安全

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53. 麻酔科領域の新機材, 新技術, 新知見

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54. 新しい人工呼吸

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55. 集中治療(1) 呼吸・循環管理

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56. 集中治療(2) 体液, 栄養, 感染の管理

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57. 集中治療(3) ICU における鎮痛と鎮静

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58. 集中治療(4) ICU におけるモニター

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59. 集中治療(5) 小児集中治療

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60. 集中治療(6) 血液浄化療法

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