専門医のための精神科臨床リュミエール16　脳科学エッセンシャル

出版社： 中山書店
著者：
発行日： 2010-07-10
分野： 臨床医学：内科  >  精神医学
ISBN： 9784521731308
シリーズ： 専門医のための精神科臨床リュミエール
電子書籍版： 2010-07-10 （初版第2刷）
書籍・雑誌
≪全国送料無料でお届け≫
取寄せ目安：8～14営業日

9,900 円(税込)

購入する
電子書籍
章別単位での購入はできません
ブラウザ、アプリ閲覧

9,900 円(税込)

購入する

商品紹介

脳科学研究の進歩は著しいものがあり，精神医学の進歩も脳科学に負うところが大きくなっています。本巻は，精神科医に向けて簡明に書かれた脳科学の書として，最先端の脳科学研究のエッセンスを幅広く集約し，イラストを多用して視覚的に理解しやすくしたものです。脳から回路、そして分子へと脳を俯瞰した脳科学の入門書です。

目次

  • 専門医のための精神科臨床リュミエール16　脳科学エッセンシャル

    ―目次―

    1．中枢神経系の構造と機能
    2．分子生物学
    3．精神薬理学
    4．神経生理学と脳画像研究
    5．神経心理学と認知科学

この書籍の参考文献

参考文献のリンクは、リンク先の都合等により正しく表示されない場合がありますので、あらかじめご了承下さい。

本参考文献は電子書籍掲載内容を元にしております。

I 中枢神経系の構造と機能

P.7 掲載の参考文献
Nieuwenhuys R, Voogd J, van Huijzen Chr. The Human Central Nervous System : A Synopsis and Atlas, 3rd revised edition. Berlin, Tokyo : Springer-Verlag ; 1988/水野昇ほか (訳). 図説 中枢神経系, 第2版. 東京 : 医学書院 ; 1991.
 
Martin JH. Neuroanatomy : Text and Atlas, 3rd edition. New York : McGraw-Hill ; 2003/野村嶬ほか (監訳). マーティン 神経解剖学-テキストとアトラス. 新潟 : 西村書店 ; 2007.
 
Kandel ER, Schwartz JH, Jessel TM (eds). Principles Neural Science, 4th edition. New York, Tokyo : McGraw-Hill ; 2000.
 
Standring S. Gray's Anatomy : The Anatomical Basis of Clinical Practice, 40th edition. Edinburgh : Churchill Livingstone/Elsevier ; 2008.
 
P.11 掲載の参考文献
1) Craig AD. How do you feel? Interoception : The sense of the physiological condition of the body. Nat Rev Neurosci 2002 ; 3 : 655-666.
 
Nieuwenhuys R, Voogd J, van Huijzen Chr. The Human Central Nervous System : A Synopsis and Atlas, 3rd revised edition. Berlin, Tokyo : Springer-Verlag ; 1988/水野昇ほか (訳). 図説中枢神経系, 第2版. 東京 : 医学書院 ; 1991.
 
P.14 掲載の参考文献
1) 高橋努, 鈴木道雄. 気になる脳部位 : 島. 分子精神医学 2008 ; 8 : 357-360.
 
2) 永井道明, 岸浩一郎, 加藤敏. 大脳皮質島葉の構造と諸機能-最近の研究の展望. 神経研究の進歩 2002 ; 46 : 157-174.
 
3) 永井道明, 岸浩一郎, 加藤敏. 大脳皮質島葉と心身機能. 精神医学 2003 ; 45 : 6-20.
 
4) Craig AD. How do you feel? Interoception : The sense of the physiological condition of the body. Nat Rev Neurosci 2002 ; 3 : 655-666.
 
5) Craig AD. How do you feel-now? The anterior insula and human awareness. Nat Rev Neurosci 2009 ; 10 : 59-70.
 
6) Nagai M, Kishi K, Kato S. Insular cortex and neuropsychiatric disorders : A review of recent literature. Eur Psychiatry 2007 ; 22 : 387-394.
PubMed
7) Biver F, et al. Serotonin 5-HT2 receptor imaging in major depression : Focal changes in orbito-insular cortex. Br J Psychiatry 1997 ; 171 : 444-448.
PubMed
8) Kennedy SH, et al. Changes in regional brain glucose metabolism measured with positron emission tomography after paroxetine treatment of major depression. Am J Psychiatry 2001 ; 158 : 899-905.
PubMed
9) Cameron OG, et al. Reduced gamma-aminobutyric acid (A) -benzodiazepine binding sites in insular cortex of individuals with panic disorder. Arch Gen Psychiatry 2007 ; 64 : 793-800.
PubMed
10) Rauch SL, et al. The functional neuroanatomy of anxiety : A study of three disorders using positron emission tomography and symptom provocation. Biol Psychiatry 1997 ; 42 : 446-452.
PubMed
11) Glahn DC, et al. Meta-analysis of gray matter anomalies in schizophrenia : Application of anatomic likelihood estimation and network analysis. Biol Psychiatry 2008 ; 64 : 774-781.
PubMed
12) Takahashi T, et al. Volumetric MRI study of the short and long insular cortices in schizophrenia spectrum disorders. Psychiatry Res 2005 ; 138 : 209-220.
 
13) Takahashi T, et al. Insular cortex gray matter changes in individuals at ultra-high-risk of developing psychosis. Schizophr Res 2009 ; 111 : 94-102.
PubMed
永井道明, 岸浩一郎, 加藤敏. 大脳皮質島葉の構造と諸機能-最近の研究の展望. 神経研究の進歩 2002 ; 46 : 157-174.
 
Craig AD. How do you feel? Interoception : The sense of the physiological condition of the body. Nat Rev Neurosci 2002 ; 3 : 655-666.
 
Nagai M, Kishi K, Kato S. Insular cortex and neuropsychiatric disorders : A review of recent literature. Eur Psychiatry 2007 ; 22 : 387-394.
PubMed
P.17 掲載の参考文献
1) Harlow JM. Recovery from the passage of an iron bar through the head. Publ Mass Med Soc 1868 ; 2 : 327-346.
 
2) Saver JL, Damasio AR. Preserved access and processing of social knowledge in a patient with acquired sociopathy due to ventromedial frontal damage. Neuropsychologia 1991 ; 29 : 1241-1249.
 
3) Damasio AR. The somatic marker hypothesis and the possible functions of the prefrontal cortex. Philos Trans R Soc Lond B Biol Sci 1996 ; 351 : 1413-1420.
PubMed
4) Bechara A, et al : Insensitivity to future consequences following damage to human prefrontal cortex. Cognition 1994 ; 50 : 7-15.
PubMed
5) Dunn BD, Dalgleish T, Lawrence AD. The somatic marker hypothesis : A critical evaluation. Neurosci Biobehav Rev 2006 ; 30 (2) : 239-271.
PubMed
Damasio AR. Decartes' Error : Emotion, Reason, and the Human Brain. New York : Grosset/Putnam ; 1994/田中三彦 (訳). 生存する脳-心と脳と身体の神秘. 東京 : 講談社 ; 2000.
 
Damasio AR, Tranel D, Damasio H. Somatic markers and the guidance of behaviour : Theory and preliminary testing. In : Levin HS, et al (eds). Frontal Lobe Function and Dysfunction. New York : Oxford University Press ; 1991. pp217-229.
 
Damasio AR. Looking for Spinoza : Joy, Sorrow, and the Feeling Brain. New York : Harcourt ; 2003/田中三彦 (訳). 感じる脳 情動と感情の脳科学 よみがえるスピノザ. 東京 : ダイヤモンド社 ; 2005.
 
P.24 掲載の参考文献
Nieuwenhuys R, Voogd J, van Huijzen Chr. The Human Central Nervous System : A Synopsis and Atlas, 3rd revised edition. Berlin, Tokyo : Springer-Verlag ; 1988/水野昇ほか (訳). 図説 中枢神経系, 第2版. 東京 : 医学書院 ; 1991.
 
Martin JH. Neuroanatomy : Text and Atlas, 3rd edition. New York : McGraw-Hill ; 2003/野村嶬ほか (監訳). マーティン神経解剖学-テキストとアトラス. 新潟 : 西村書店 ; 2007.
 
Kandel ER, Schwartz JH, Jessel TM (eds). Principles Neural Science, 4th edition. New York, Tokyo : McGraw-Hill ; 2000.
 
Standring S. Gray's Anatomy : The Anatomical Basis of Clinical Practice, 40th edition. Edinburgh : Churchill Livingstone/Elsevier ; 2008.
 
Jouvet M. Le Sommeil et Le Reve. Paris : Odile Jacob ; 1992/北浜邦夫 (訳). 睡眠と夢. 東京 : 紀伊國屋書店 ; 1997.
 
P.26 掲載の参考文献
1) 苧阪直行. 脳と意識 : 最近の研究の動向. 苧阪直行 (編). 脳と意識. 東京 : 朝倉書店 ; 1997. pp1-p44.
 
2) Moruzzi G, Magoun HW. Brain stem reticular formation and activation of the EEG. Electroencephalogr Clin Neurophysiol 1949 ; 1 : 455-473.
PubMed
3) Young GB. Disorders of consciousness. Coma. Ann N Y Acad Sci 2009 ; 1157 : 32-47.
PubMed
4) Plum F, Posner JB. The Diagnosis of Stupor and Coma, 3rd edition. Philadelphia : FA Davis ; 1980/川村純一郎 (訳). プラム昏迷と昏睡の診断, 第3版. 新潟 : 西村書店 ; 1982.
 
P.28 掲載の参考文献
1) Moruzzi G, Magoun HW. Brain stem reticular formation and activation of the EEG. Electroencephalogr Clin Neurophysiol 1949 ; 1 : 455-473.
PubMed
2) Saper CB, Chou TC, Scammell TE. The sleep switch : Hypothalamic control of sleep and wakefulness. Trends Neurosci 2001 ; 24 : 726-731.
PubMed
3) Landolt HP. Sleep homeostasis : A role for adenosine in humans? Biochem Pharmacol 2008 ; 75 : 2070-2079.
PubMed
4) 裏出良博. 睡眠の液性調節と視床下部. Brain Medical 2006 ; 18 : 11-17.
Medical*Online
5) 小山純正. レム睡眠の中枢機序. Brain Medical 2006 ; 18 : 33-41.
Medical*Online
6) Adrien J. Neurobiological bases for the relation between sleep and depression. Sleep Medicine Reviews 2002 ; 6 : 341-351.
PubMed
7) 日本睡眠学会 (編). 睡眠学. 東京 : 朝倉書店 ; 2009.
 
北浜邦夫. 脳と睡眠. 東京 : 朝倉書店 ; 2009.
 
Saper CB, Scammell TE, Lu J. Hypothalamic regulation of sleep and circadian rhythms. Nature 2005 ; 437 : 1257-1263.
PubMed
P.31 掲載の参考文献
1) Fukuda M, Ono T. Amygdala hypothalamic control of feeding-behavior in monkey-Single-cell responses before and after reversible blockade of temporal cortex or amygdala projections. Behav Brain Res 1993 ; 55 : 233-241.
PubMed
2) Sakurai T. The neural circuit of orexin (hypocretin) : Maintaining sleep and wakefulness. Nat Rev Neurosci 2007 ; 8 : 171-181.
PubMed
3) Nishino S. Clinical and neurobiological aspects of narcolepsy. Sleep Med 2007 ; 8 : 373-399.
PubMed
4) Hassani OK, Lee MG, Jones BE. Melanin-concentrating hormone neurons discharge in a reciprocal manner to orexin neurons across the sleep-wake cycle. Proc Natl Acad Sci U S A 2009 ; 106 : 2418-2422.
 
5) 本多真. ナルコレプシーと睡眠制御機構. 加藤忠史 (編). 精神の脳科学. 東京 : 東京大学出版会 ; 2008. pp221-261.
 
Nishino S, Sakurai T (eds). The Orexin/Hypocretin System Physiology and Pathophysiology. Totowa, New Jersey : Humana Press ; 2006.
 
桜井武. ナルコレプシーの分子機構とオレキシンの機能. 日本臨牀 2008 ; 66 (増刊 2) : 96-106.
 
北浜邦夫. 脳と睡眠. 東京 : 朝倉書店 ; 2009.
 
P.35 掲載の参考文献
Nieuwenhuys R, Voogd J, van HuiJzen Chr. The Human Central Nervous System : A synopsis and Atlas. 3rd revised edition. Berlin, Tokyo : Spreinger-Verlag ; 1988. /水野昇ほか (訳). 図説 中枢神経系, 第2版. 東京 : 医学書院 ; 1991.
 
Martin JH. Neuroanatomy : Text and Atlas. 3rd edition. New York : MacGraw-Hill ; 2003. /伊藤和夫ほか (監訳). マーティン神経解剖学-テキストとアトラス. 新潟 : 西村書店 ; 2007.
 
P.38 掲載の参考文献
1) 泉剛, 小山 司. 不安障害の薬理/抗不安薬. 樋口輝彦ほか (編). 臨床精神薬理ハンドブック, 第2版. 東京 : 医学書院 ; 2009.
 
2) Ehrlich I, et al. Amygdala inhibitory circuits and the control of fear memory. Neuron 2009 ; 62 : 757-771.
PubMed
3) Holmes A. Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease. Neurosci Biobehav Rev 2008 ; 32 (7) : 1293-1314.
PubMed
4) 泉剛, 朝倉聡, 吉岡充弘. 社会不安障害の脳機能と薬物療法. 臨床精神薬理 2009 ; 12 (9) : 1933-1937.
 
P.41 掲載の参考文献
1) 野村理朗. 顔と認知神経科学. 野村理朗, 竹原卓真 (編). 「顔」研究の最前線. 京都 : 北大路書房 ; 2004. pp85-104.
 
2) Okada T, et al. Involvement of medial temporal structures in reflexive attentional shift by gaze. Soc Cogn Affect Neurosci 2008 ; 3 (1) : 80-88.
PubMed
3) 岡田俊. 統合失調症における顔表情認知. 野村理朗, 竹原卓真 (編). 「顔」研究の最前線. 京都 : 北大路書房 ; 2004. pp128-138.
 
4) 岡田俊ほか. 統合失調症におけるかお表情認知の通文化研究. 精神医学 2003 ; 45 : 535-541.
 
5) 岡田俊. 精神疾患における情動処理の生物学的基盤. 心理学評論 2004 ; 47 (1) : 143-149.
 
6) 馬場天信. アレキサイミアにおける表情認知障害. 野村理朗, 竹原卓真 (編). 「顔」研究の最前線. 京都 : 北大路書房 ; 2004. pp139-147.
 
7) 佐藤弥. 広汎性発達障害における対人相互作用の障害の神経基盤. 岡田俊 (編). 精神医学入門. 東京 : 星和書店 ; 2007. pp243-247.
 
8) 岡田俊. 広汎性発達障害と認知機能. 山内俊雄 (編). 精神疾患と認知機能. 東京 : 新興医学出版社 ; 2009. pp226-232.
 
9) 十一元三, 岡田俊, 崎濱盛三. 高機能自閉症における共同注意の障害. 第44回日本児童青年精神医学会, 福岡, 2003.
 
野村理朗, 竹原卓真 (編). 「顔」研究の最前線. 京都 : 北大路書房 ; 2004.
 
P.42 掲載の参考文献
Adolphs R. Neural systems for recognizing emotion. Curr Opin Neurobiol 2002 ; 12 : 169-177.
PubMed
Livingstone M, Hubel D. Segregation of form, color, movement, and depth : Anatomy, physiology, and perception. Science 1988 ; 240 : 740-749.
PubMed
Vuilleumier P, et al. Distinct spatial frequency sensitivities for processing faces and emotional expressions. Nat Neurosci 2003 ; 6 : 624-631.
PubMed
P.46 掲載の参考文献
1) 扇谷明. 南方熊楠のてんかん : 病跡学的研究. 精神神経学雑誌 2006 ; 108 : 132-139.
 
2) Bancaud J, et al. Anatomical origin of deja vu and vivid 'memories' in human temporal lobe epilepsy. Brain 1994 ; 117 (Pt 1) : 71-90.
 
3) Kovacs N, et al. Neuroimaging and cognitive changes during deja vu. Epilepsy Behav 2009 ; 14 (1) : 190-196.
PubMed
4) Diana RA, Yonelinas AP, Ranganath C. Imaging recollection and familiarity in the medial temporal lobe : A three-component model. Trends Cogn Sci 2007 ; 11 (9) : 379-386.
PubMed
5) Wilson MA, McNaughton BL. Reactivation of hippocampal ensemble memories during sleep. Science 1994 ; 265 (5172) : 676-679.
PubMed
6) Spatt J. Deja vu : Possible parahippocampal mechanisms. J Neuropsychiatry Clin Neurosci 2002 ; 14 (1) : 6-10.
PubMed
兼本浩祐. てんかん学ハンドブック, 第2版. 東京 : 医学書院 ; 2006.
 
P.53 掲載の参考文献
Kandel ER, Schwartz JH, Jessell TM. Principles of Neural Science, 4th edition. New York : McGraw-Hill ; 2000.
 
坂田英夫. 頭頂葉. 東京 : 医学書院 ; 2006.
 
Fuster JM. The Prefrontal Cortex, 3rd edition. Lippincott-Raven ; 1997/福居顯二 (監訳) 前頭前皮質-前頭葉の解剖学, 生理学, 神経心理学. 東京 : 新興医学出版社 ; 2006.
 
Libet B. Mind Time. Cambridge, Massachusetts : Harvard University Press ; 2004/下條信輔 (訳). マインド・タイム. 東京 : 岩波書店 ; 2005.
 
Haggard P. Human volition : Towards a neuroscience of will. Nat Rev Neurosci 2008 ; 9 : 934-946.
PubMed
Rizzolatti G, Sinigaglia C. So quell che fai : Il cervello che agisce e I neuroni specchio. Milano : Raffaello Cortina Editore ; 2006/柴田裕之 (訳). ミラーニューロン. 東京 : 紀伊國屋書店 ; 2009.
 
P.55 掲載の参考文献
1) 加藤元博. 脳波の発生機序 : 解剖と生理. 日本臨床神経生理学会認定委員会 (編). モノグラフ臨床脳波を基礎から学ぶ人のために. 東京 : 有限責任中間法人日本臨床神経生理学会 ; 2008. pp1-10.
 
2) Buzsaki G. Rhythms of the Brain. New York : Oxford University Press ; 2006.
 
3) S teriade M, et al. Fast oscillations (20-40Hz) in thalamocortical systems and their potentiation by mesopontine cholinergic nuclei in the cat. Proc Natl Acad Sci U S A 1991 ; 88 (10) : 4396-4400.
 
4) Spencer KM, et al. Abnormal neural synchrony in schizophrenia. J Neurosci 2003 ; 23 (19) : 7407-7411.
 
5) Uhlhaas PJ, et al. Dysfunctional long-range coordination of neural activity during Gestalt perception in schizophrenia. J Neurosci 2006 ; 26 (31) : 8168-8175.
PubMed
6) Roopun AK, et al. Region-specific changes in gamma and beta2 rhythms in NMDA receptor dysfunction models of schizophrenia. Schizophr Bull 2008 ; 34 (5) : 962-973.
PubMed
Uhlhaas PJ, Siuger W. Abnormal neural oscillations and synchrony in schizophrenia. Nat Rev Neurosci 2010 ; 11 (2) : 100-113.
 
P.58 掲載の参考文献
1) Fuster JM. The Prefrontal Cortex, 4th edition. Boston : Academic Press ; 2008.
 
2) Goldman-Rakic PS. Regional and cellular fractionation of working memory. Proc Natl Acad Sci U S A 1996 ; 93 : 13473-13480.
PubMed
3) Silver H, et al. Working memory deficit as a core neuropsychological dysfunction in schizophrenia. Am J Psychiatry 2003 ; 160 : 1809-1816.
PubMed
4) Okubo Y, et al. Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET. Nature 1997 ; 385 : 634-636.
PubMed
5) Brewer WJ, et al. Generalized and specific cognitive performance in clinical high-risk cohorts : A review highlighting potential vulnerability markers for psychosis. Schizophr Bull 2006 ; 32 : 538-555.
PubMed
6) Callicot JH, et al. Complexity of prefrontal cortical dysfunction in schizophrenia : More than up and down. Am J Psychiatry 2003 ; 160 : 2209-2215.
 
7) Minzenberg MJ, et al. Meta-analysis of 41 functional neuroimaging studies of executive function in schizophrenia. Arch Gen Psychiatry 2009 ; 66 : 811-822.
PubMed
8) Suzuki M, et al. Differential contributions of prefrontal and temporolimbic pathology to mechanisms of psychosis. Brain 2005 ; 128 : 2109-2122.
PubMed
9) Sun D, et al. Progressive brain structural changes mapped as psychosis develops in 'at risk' individuals. Schizophr Res 2009 ; 108 : 85-92.
PubMed
10) Harrison PJ, Weinberger DR. Schizophrenia genes, gene expression, and neuropathology : On the matter of their convergence. Mol Psychiatry 2005 ; 10 : 40-68.
PubMed
11) Lewis DA, Hashimoto T, Volk DW. Cortical inhibitory neurons and schizophrenia. Nat Rev Neurosci 2005 ; 6 : 312-324.
PubMed
12) Kumari V, et al. Dorsolateral prefrontal cortex activity predicts responsiveness to cognitive-behavioral therapy in schizophrenia. Biol Psychiatry 2009 ; 66 : 594-602.
PubMed
Fuster JM. The Prefrontal Cortex, 4th edition. Boston : Academic Press ; 2008.
 
Goldman-Rakic PS. Regional and cellular fractionation of working memory. Proc Natl Acad Sci U S A 1996 ; 93 : 13473-13480.
PubMed
Brewer WJ, et al. Generalized and specific cognitive performance in clinical high-risk cohorts : A review highlighting potential vulnerability markers for psychosis. Schizophr Bull 2006 ; 32 : 538-555.
PubMed
Callicot JH, et al. Complexity of prefrontal cortical dysfunction in schizophrenia : More than up and down. Am J Psychiatry 2003 ; 160 : 2209-2215.
 
Harrison PJ, Weinberger DR. Schizophrenia genes, gene expression, and neuropathology : On the matter of their convergence. Mol Psychiatry 2005 ; 10 : 40-68.
PubMed
Lewis DA, Hashimoto T, Volk DW. Cortical inhibitory neurons and schizophrenia. Nat Rev Neurosci 2005 ; 6 : 312-324.
PubMed
P.63 掲載の参考文献
1) Carlson NR. Physiology of Behavior, 9th edition. Pearson Education ; 2007/ネイル・カールソン (著). 中村克樹, 泰羅雅登 (監訳). 神経科学テキスト 脳と行動, 第2版. 東京 : 丸善 ; 2008.
 
2) Kolb B, Whishaw IQ. Fundamentals of Human Neuropsychology, 5th edition. New York : Worth Publishers ; 2003.
 
3) Glasser MF, Rilling JK. Feature Article : DTI Tractography of the human brain's language pathways. Cereb Cortex 2008 ; 18 : 2471-2482.
 
4) Cummings JL. Dementia syndromes : Neurobehavioral and neuropsychiatric features. J Clin Psychiatry 1987 ; 48 : 3-8.
PubMed
5) Catania M, Mesulam M. The arcuate fasciculus and the disconnection theme in language and aphasia : History and current state. Cortex 2008 ; 44 : 953-961.
 
6) Grefkes C, Fink GR. The functional organization of the intraparietal sulcus in humans and monkeys. J Anat 2005 ; 207 : 3-17.
PubMed
7) Husain M, Nachev P. Space and the parietal cortex. Trends Cogn Sci 2007 ; 11 : 30-36.
PubMed
8) Haaland KY, Harrington DL, Knight RT. Neural representations of skilled movement. Brain 2000 ; 123 : 2306-2313.
PubMed
P.66 掲載の参考文献
Nieuwenhuys R, Voogd J, van Huijzen Chr. The Human Central Nervous System : A Synopsis and Atlas, 3rd revised edition. Berlin, Tokyo : Springer-Verlag ; 1988/水野昇ほか (訳). 図説 中枢神経系, 第2版. 東京 : 医学書院 ; 1991.
 
Martin JH. Neuroanatomy : Text and Atlas. 3rd edition. New York : McGraw-Hill ; 2003/野村嶬ほか (監訳). マーティン 神経解剖学-テキストとアトラス. 新潟 : 西村書店 ; 2007.
 
Fanselow MS, Dong HW, Are dorsal and ventral hippocampus functionally distinct structure? Neuron 2010 ; 65 : 7-19.
PubMed
P.71 掲載の参考文献
1) Scoville WB, Milner B. Loss of recent memory after bilateral hippocampal lesions. J Neurol Neurosurg Psychiatry 1957 ; 20 : 11-21.
PubMed
2) Corkin S, et al. H. M.'s medial temporal lobe lesion : Findings from magnetic resonance imaging. J Neurosci 1997 ; 17 : 3964-3979.
 
3) Zola-Morgan S, Squire LR, Amaral DG. Human amnesia and the medial temporal region : Enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus. J Neurosci 1986 ; 6 : 2950-2967.
PubMed
4) Yoneda Y, et al. MRI volumetry of medial temporal lobe structures in amnesia following herpes simplex encephalitis. Eur Neurol 1994 ; 34 : 243-252.
PubMed
5) Simons JS, et al. Recollection-based memory in frontotemporal dementia : Implications for theories of long-term memory. Brain 2002 ; 125 : 2523-2536.
PubMed
6) Silva AJ, et al. Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice. Science 1992 ; 257 : 206-211.
PubMed
7) Nakazawa K, et al. Requirement for hippocampal CA3 NMDA receptors in associative memory recall. Science 2002 ; 297 : 211-218.
PubMed
8) Louie K, Wilson MA. Temporally structured replay of awake hippocampal ensemble activity during rapid eye movement sleep. Neuron 2001 ; 29 : 145-156.
PubMed
9) Aggleton JP, Brown MW. Episodic memory, amnesia, and the hippocampal-anterior thalamic axis. Behav Brain Sci 1999 ; 22 : 425-444.
PubMed
10) Irle E, et al. Memory disturbances following anterior communicating artery rupture. Ann Neurol 1992 ; 31 : 473-480.
PubMed
11) Ikeda M, et al. Amnestic people with Alzheimer's disease who remembered the Kobe earthquake. Br J Psychiatry 1998 ; 172 : 425-428.
PubMed
12) Mori E, et al. Amygdalar volume and emotional memory in Alzheimer's disease. Am J Psychiatry 1999 ; 156 : 216-222.
PubMed
13) Cahill L, et al. The amygdala and emotional memory. Nature 1995 ; 377 : 295-296.
PubMed
中沢一俊. 記憶. 田中啓治 (編). 認識と行動の脳科学. 東京 : 東京大学出版会 ; 2008. pp123-201.
 
P.75 掲載の参考文献
Nakagawa S. Possible role of adult hippocampal neurogenesis in depression and antidepressant action. In : Shirayama Y, et al (eds). Recent Developments on Depression Research. Trivandrum : Research Signpost ; 2009. pp1-12.
 
Feder A, Nestler EJ, Charney DS. Psychobiology and molecular genetics of resilience. Nat Rev Neurosci 2009 ; 10 : 446-457.
PubMed
McEwen BS. Central effects of stress hormones in health and disease : Understanding the protective and damaging effects of stress and stress mediators. Eur J Pharmacol 2008 ; 583 : 174-185.
PubMed
Pttenger C, Duman RS. Stress, depression, and neuroplasticity : A convergence of mechanisms. Neuropsychopharmacology 2008 ; 33 : 88-109.
 
Sala M, et al. Stress and hippocampal abnormalities in psychiatric disorder. Eur Neuropsychopharmacol 2004 ; 14 : 393-405.
PubMed
P.81 掲載の参考文献
Kandel ER, Schwartz JH, Jessel TM (eds). Principles Neural Science, 4th edition. New York, Tokyo : MacGraw-Hill ; 2000.
 
Schmahmann JD, Weilburg JB, Sherman JC. The neuropsychology of the cerebellum-insights from the clinic. Cerebellum 2007 ; 6 : 254-267.
 
Parvizi J, et al. Pathological laughter and crying : A link to the cerebellum. Brain 2001 ; 124 : 1708-1719.
 
P.83 掲載の参考文献
1) Schmahmann JD, Sherman JC. The cerebellar cognitive affective syndrome. Brain 1998 ; 121 : 561-579.
PubMed
2) 遠藤太郎, 染矢俊幸. 広汎性発達障害の脳画像研究. 分子精神医学 2007 ; 7 : 37-41.
 
3) 一宮哲哉, 大久保善朗. 統合失調症における小脳研究の治験. 分子精神医学 2007 ; 7 : 9-13.
 
4) Ichimiya T, et al. Reduced volume of the cerebellar vermis in neuroleptic-naive schizophrenia. Biol Psychiatry 2001 ; 49 : 20-27.
PubMed
5) Andreasen NC, Paradiso S, O'Leary DS. Cognitive dysmetria as an integrative theory of schizophrenia : A dysfunction in cortical-subcortical-cerebellar circuitry? Schizophr Bull 1998 ; 24 : 203-218.
PubMed
6) Honey GD, et al. Functional dysconnectivity in schizophrenia associated with attentional modulation of motor function. Brain 2005 ; 128 : 2597-2611.
PubMed
7) 伊藤正男. 小脳の構造と高次神経機能. 分子精神医学 2007 ; 7 : 2-8.
Medical*Online
P.88 掲載の参考文献
彦坂興秀. 眼と精神. 東京 : 医学書院 ; 2003.
 
Heimer L. A new anatomical frameword for neuropsychiatric disorders and drug abuse. Am J Psychiatry 2003 ; 160 : 1726-1739.
 
Wichmann T, DeLong MR. Deep brain stimulation for neurologic and neuropsychiatric disorders. Neuron 2006 ; 52 : 197-204.
PubMed
Everitt BJ, Robbins TW. Neural systems of reinforcement for drug addiction : from actions to habits to compulsion. Nat Neurosci 2005 ; 8 : 1481-1489.
PubMed
Hikosaka O, et al. Parallel neural networks for learning sequential procedures. Trend Neurosci 1999 ; 22 : 464-471.
PubMed
P.90 掲載の参考文献
1) 渡辺雅彦, 寺島俊雄. ヒトの神経系の構造. 伊藤正男 (監修). 脳神経科学. 東京 : 三輪書店 ; 2003. pp15-41.
 
2) Albert ML, Feldman RG, Willis AL. The "subcortcal dementia" of progressive supranuclear palsy. J Neurol Neurosurg Psychiatry 1974 ; 37 : 121-130.
 
3) Cummings JL, Cunningham K. Obsessive-compulsive disorders in Huntington's disease. Biol Psychiatry 1992 ; 31 : 263-270.
PubMed
4) 高橋克朗. IV. 強迫性障害. 病因と病態生理. 松下正明 (総編集). 臨床精神医学講座 5 神経症性障害・ストレス関連障害. 東京 : 中山書店 ; 1997. pp329-361.
 
5) Tonkonogy JM, Smith TW, Barreia PJ. Obsessivecompulsive disorders in Pick's disease. J Neuropsychiatry Clin Neurosci 1994 ; 6 : 176-180.
 
6) Denckla MB. Neurological examination. In : Rapoport JL (ed). Obsessive-compulsive Disorder in Children and Adolescents. Washington DC : American Psychiatric Press ; 1989. pp107-118.
 
P.92 掲載の参考文献
1) Kalivas PW, Volkow ND. The neural basis of addiction : A pathology of motivation and choice. Am J Psychiatry 2005 ; 162 : 1403-1413.
PubMed
2) Schultz W. Predictive reward signal of dopamine neurons. J Neurophysiol 1998 ; 80 : 1-27.
PubMed
3) Chaudhuri RK, Healy DG, SchapiraAH. Non-motor symptoms of Parkinson's disease : Diagnosis and management. Lancet Neurol 2006 ; 5 : 235-245.
 
4) 志々田一宏, 岡本泰昌. うつ病における基底核の役割. 分子精神医学 2008 ; 8 : 321-326.
Medical*Online
5) Schlagenhauf F, et al. Reward system activation in schizophrenic patients switched from typical neuroleptics to olanzapine. Psychopharmacol 2008 : 196 (4) : 673-684.
 
縄田陽子, 山本経之. 薬物自己投与実験法を用いての薬物依存研究. 日本アルコール・薬物医学会雑誌 2008 ; 43 : 158-165.
 
山本経之, 縄田陽子. 大脳基底核と脳内報酬 ; ドパミン伝達の観点から. 分子精神医学 2008 ; 8 : 314-320.
 
P.95 掲載の参考文献
1) Baxter LR, et al. Local cerebral glucose metabolic rates in obsessive-compulsive disorder - A comparison with rates in unipolar depression and in normal controls. Arch Gen Psychiatry 1987 ; 44 : 211-218.
PubMed
2) Saxena S, et al. Neuroimaging and frontal-subcortical circuitry in obsessive-compulsive disorder. Br J Psychiatry Suppl 1998 ; 35 : 26-37.
PubMed
3) Kalra SK, Swedo SE. Children with obsessive-compulsive disorder : Are they just "little adult"? J Clin Invest 2009 ; 119 : 737-746.
PubMed
4) Mataix-Cols D, et al. Distinct neural correlates of washing,checking and hoarding symptom dimensions in obsessive-compulsive disorder. Arch Gen Psychiatry 2004 ; 61 ; 564-576.
PubMed
5) 黒木俊秀, 中尾智博, Mataix-Cols D. 強迫性障害における情動と認知. 精神科治療学 2005 ; 20 : 355-361.
 
中尾智博. 強迫性障害. 福田正人 (編). 専門医のための精神科臨床リュミエール 2 精神疾患と脳画像. 東京 : 中山書店 ; 2008. pp100-110.
 
Schwartz JM. Neuroanatomical aspects of cognitive-behavioural herapy response in obsessive-compulsive disorder. An evolving perspective on brain and behaviour. Br J Psychiatry Suppl 1998 ; 35 : 38-44.
 
Hollander E, Wong CM. Obsessive-compulsive spectrum disorders. J Clin Psychiatry 1995 ; 56 Suppl 4 : 3-6.
 
P.98 掲載の参考文献
1) 佐野豊. 神経科学-形態学的基礎 間脳 [2] 視床上部, 視床下域, 視覚系. 東京 : 医学書院 ; 2006.
 
2) 岡本仁, 相澤秀紀. 気になる脳部位 (第1回) 手綱核. 分子精神医学 2008 ; 8 (2) : 134-138.
 
3) Hikosaka O. Habenula. Scholarpedia 2007 ; 2 (6) : 2703.
 
4) Jhou TC, et al. The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses. Neuron 2009 ; 61 (5) : 786-800.
PubMed
5) Matsumoto M, Hikosaka O. Lateral habenula as a source of negative reward signals in dopamine neurons. Nature 2007 ; 447 (7148) : 1111-1115.
PubMed
6) Morris JS, et al. Covariation of activity in habenula and dorsal raphe nuclei following tryptophan depletion. Neuroimage 1999 ; 10 (2) : 163-172.
PubMed
7) Roiser JP, et al. The effects of tryptophan depletion on neural responses to emotional words in remitted depression. Biol Psychiatry 2009 ; 66 (5) : 441-450.
PubMed
8) Ranft K, et al. Evidence for structural abnormalities of the human habenular complex in affective disorders but not in schizophrenia. Psychol Med 2009 ; 12 : 1-11.
PubMed
佐野 豊. 神経科学-形態学的基礎 間脳 [2] 視床上部, 視床下域, 視覚系. 東京 : 医学書院 ; 2006.
 
岡本仁, 相澤秀紀. 気になる脳部位 (第1回) 手綱核. 分子精神医学 2008 ; 8 (2) : 134-138.
 
Hikosaka O. Habenula. Scholarpedia 2007 ; 2 (6) : 2703.
 
P.104 掲載の参考文献
Heimer L, Van Hoesen GW. The limbic lobe and its output channels : Implications for emotional functions and adaptive behavior. Neurosci Biobehav Rev 2006 ; 30 : 126-147.
PubMed
Vogt BA. Pain and emotion interactions in subregions of the cingulated gyrus. Nat Rev Neurosci 2005 ; 6 : 533-544.
PubMed
Vann SD, Aggleton JP, Maguire EA. What does the retrosplenial cortex do? Nat Rev Neurosci 2009 ; 10 : 792-802.
PubMed
Buckner RL, Andrews-Hanna JR, Schacter DL. The brain's default network : Anatomy, function, and relevance to disease. Ann N Y Acad Sci 2008 ; 1124 : 1-38.
 
van Beilen M, Vogt BA, Leenders KL. Increased activation in cingulated cortex in conversion disorder : What does it mean? J Neurol Sci 2010 ; 289 : 155-158.
PubMed
Swanson LW. Cerebral hemisphere regulation of motivated behavior. Brain Res 2000 ; 886 : 113-164.
PubMed
Saper CB. Homeostatic, circadian, and emotional regulation of sleep. J Comp Neurol 2005 ; 493 : 92-98.
 
P.106 掲載の参考文献
1) Vogt BA. Pain and emotion interactions in subregions of the cingulate gyrus. Nat Rev Neurosci 2005 ; 6 : 533-544.
PubMed
2) Yamasue H, et al. Voxel-based analysis of MRI reveals anterior cingulate gray-matter volume reduction in posttraumatic stress disorder due to terrorism. Proc Natl Acad Sci U S A 2003 ; 100 : 9039-9043.
PubMed
3) Milad MR, Quirk GJ. Neurons in medial prefrontal cortex signal memory for fear extinction. Nature 2002 ; 420 : 70-74.
PubMed
4) Abe O, et al. Voxel-based diffusion tensor analysis reveals aberrant anterior cingulum integrity in posttraumatic stress disorder due to terrorism. Psychiatry Res Neuroimaging 2006 ; 146 : 231-242.
PubMed
5) Drevets WC, et al. Subgenual prefrontal cortex abnormalities in mood disorders. Nature 1997 ; 386 : 824-827.
PubMed
Herry C, Mons N. Resistance to extinction is associated with impaired immediate early gene induction in medial prefrontal cortex and amygdala. Eur J Neurosci 2004 ; 20 : 781-790.
PubMed
山末英典, 笠井清登. 統合失調症と帯状回. Clinical Neuroscience 2005 ; 23 : 1301-1303.
 
山末英典, 笠井清登, 加藤進昌. PTSDと帯状回. Clinical Neuroscience 2005 ; 23 : 1292-1294.
 
P.109 掲載の参考文献
1) McClung CA. Circadian genes, rhythms and the biology of mood disorders. Pharmacol Ther 2007 ; 114 : 222-232.
PubMed
2) Ralph MR, et al. Transplanted suprachiasmatic nucleus determines circadian period. Science 1990 ; 247 : 975-978.
PubMed
3) Ko CH, Takahashi JS. Molecular components of the mammalian circadian clock. Hum Mol Genet 2006 ; 15 : R271-R277.
PubMed
4) Hastings MH, Reddy AB, Maywood ES. A clockwork web : Circadian timing in brain and periphery, in health and disease. Nat Rev Neurosci 2003 ; 4 : 649-661.
PubMed
5) Morin LP, Allen CN. The circadian visual system, 2005. Brain Res Rev 2006 ; 51 : 1-60.
PubMed
6) Silver R, et al. A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms. Nature 1996 ; 382 : 810-813.
 
海老原史樹文, 深田吉孝 (編). 生物時計の分子生物学. 東京 : シュプリンガー・フェアラーク東京 ; 1999.
 
ラッセル・フォスター, レオン・クライマン. 本間徳子 (訳). 生物時計はなぜリズムを刻むのか. 東京 : 日経BP社 ; 2006.
 
Takahashi JS, et al. The genetics of mammalian circadian order and disorder : Implications for physiology and disease. Nat Rev Genet 2008 ; 9 : 764-775.
PubMed
P.112 掲載の参考文献
1) Schule C. Neuroendocrinological mechanisms of actions of antidepressant drugs. J Neuroendocrinol 2007 ; 19 : 213-226.
 
2) Tyrka AR, et al. Childhood parental loss and adult hypothalamic-pituitary-adrenal function. Biol Psychiatry 2008 ; 63 : 1147-1154.
PubMed
3) de Kloet C, et al. Differences in the response to the combined DEX-CRH test between PTSD patients with and without co-morbid depressive disorder. Psychoneuroendocrinology 2008 ; 33 : 313-320.
 
4) 尾鷲登志美ほか. 大うつ病性障害の入院治療転帰と甲状腺機能との関連. 精神医学 2007 ; 49 : 797-803.
 
5) Owashi T, et al. Longitudinal neuroendocrine changes assessed by dexamethasone/CRH and growth hormone releasing hormone tests in psychotic depression. Psychoneuroendocrinology 2008 ; 33 : 152-161.
PubMed
尾鷲登志美, 上島国利. 改めてうつ病中核群を問う-神経内分泌学的視点からみたうつ病中核群. 精神科治療学 2009 ; 24 (1) : 91-96.
 
P.115 掲載の参考文献
1) Kaneko N, et al. Suppression of cell proliferation by interferon-alpha through interleukin-1 production in adult rat dentate gyrus. Neuropsychopharmacology 2006 ; 31 : 2619-2626.
PubMed
2) Snow HL. Cancer and the Cancer Process. London : Churchill ; 1893.
 
3) Parker J, et al. Chronic stress accelerate ultravioletinduced cutaneous carcinogenesis. J Am Acad Dermatol 2004 ; 51 : 919-922.
PubMed
Ader R, et al. Psychoneuroimmunology, 4th edition. San Diego : Academic Press ; 2007.
 
Hashioka S, et al. Anti-inflammatory effects of antidepressants : Possibilities for preventives against Alzheimer's disease. Central Nervous System Agents in Medicinal Chemistry 2009 ; 9 : 12-19.
PubMed
Monji A, Kato T, Kanba S. Cytokines and schizophrenia : Microglial hypothesis of schizophrenia. Psychiatry Clin Neurosci 2009 ; 63 : 257-265.
PubMed
神庭重信. こころと体の対話 : 精神神経免疫学の世界 (文春新書). 東京 : 文藝春秋 ; 1999.
 
P.121 掲載の参考文献
Sacks O. Awakenings. 1973. /春日井晶子 (訳). レナードの朝. 東京 : 早川書房 ; 2000.
 
Holstege G. The basic, somatic, and emotional components of the motor systems in mammals. In : Paxinos G (ed). The Rat Nervous System, 2nd edition. San Diego : Academic Press ; 1995. pp137-154.
 
Wild B, et al. Neural correlates of laughter and humor. Brain 2003 ; 126 : 2121-2138.
PubMed
Holstege G. Emotional innervations of facial musculature. Mov Disord 2002 ; 17S2 : S12-S16.
 
P.124 掲載の参考文献
1) 有田秀穂. 呼吸の神経性調節. 小沢瀞司 ほか (総編集). 標準生理学. 東京 : 医学書院 ; 2009. pp664-668.
 
2) 小金澤禎史, 照井直人. 血圧の神経調節. Brain Medical 2005 ; 17 (2) : 141-146.
 
江連和久. 呼吸の形成機構. 有田秀穂 (編). 呼吸の辞典. 東京 : 朝倉書店 ; 2006. pp108-118.
 
大竹一嘉. 呼吸性ニューロンの形態. 有田秀穂 (編). 呼吸の辞典. 東京 : 朝倉書店 ; 2006. pp135-148.
 
照井直人. 血管の神経支配と心臓血管中枢. 小沢瀞司ほか (総編集). 標準生理学. 東京 : 医学書院 ; 2009. pp619-624.
 
有田秀穂. 呼吸の神経性調節. 小沢瀞司 ほか (総編集). 標準生理学. 東京 : 医学書院 ; 2009. pp664-668.
 
小金澤禎史, 照井直人. 血圧の神経調節. Brain Medical 2005 ; 17 (2) : 141-146.
 
P.128 掲載の参考文献
1) American Psychiatric Association. 高橋三郎ほか (訳). 疼痛性障害. DSM-IV-TR 精神疾患の分類と診断の手引 新訂版. 東京 : 医学書院 ; 2003. pp189-191.
 
2) 細井昌子. 特集 慢性疼痛診療ガイド, 心因性慢性疼痛. 治療 2008 ; 90 (7) : 2063-2072.
 
3) 永井道明, 加藤敏. 島皮質と帯状回. Clinical Neuroscience 2005 ; 23 (11) : 1231-1235.
 
4) Tracey I, Mantyh PW. The cerebral signature for pain perception and its modulation. Neuron 2007 ; 55 (3) : 377-391.
PubMed
5) Heinricher MM, et al. Descending control of nociception : Specificity, recruitment and plasticity. Brain Res Rev 2009 ; 60 (1) : 214-225.
PubMed
P.132 掲載の参考文献
1) Noguchi H, Moore JW. A demonstration of Treponema pallidum in the brain of general paresis. J Exp Med 1913 ; 17 : 232-238.
 
2) Alzheimer A. Uber eine eigenartige Krankheitsfalle des spateren Alters. Z Gesamte Neurol Psychiatr 1911 ; 4 : 356-385.
 
3) Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 1991 ; 82 (4) : 239-259.
PubMed
4) Pick A. Uber die beziehungen der senilen Hirnatrophie zur Aphasie. Prager Medizinische Wochenschrift 1892 ; 17 : 165-7.
 
村山繁雄. 総論, 認知症の病態, 神経病理. 日本認知症学会 (編). 日本認知症学会テキスト. 東京 : 中外医学社 ; 2008. pp21-39.
 
グレイ, ジロラーミ, ポワリエ (編著). 村山繁雄 (監訳). エスクロール基本神経病理学. 新潟 : 西村書店 ; 2009.
 

II 分子生物学

P.138 掲載の参考文献
1) Lander ES, et al. Initial sequencing and analysis of the human genome. Nature 2001 ; 409 : 860-921.
PubMed
2) Stefansson H, et al. Large recurrent microdeletions associated with schizophrenia. Nature 2008 ; 455 : 232-236.
PubMed
3) Shaffer LG, et al. The discovery of microdeletion syndromes in the post-genomic era : Review of the methodology and characterization of a new 1q41q42 microdeletion syndrome. Genet Med 2007 ; 9 : 607-616.
PubMed
Strachan T, Read AP. 村松正實, 木南 凌 (監訳). ヒトの分子遺伝学, 第3版. 東京 : メディカル・サイエンス・インターナショナル ; 2005.
 
Smoller JW, Sheidley BR, Tsuang MT. Psychiatric Genetics : Applications in Clinical Practice. Arlington : American Psychiatric Publishing ; 2008.
 
P.140 掲載の参考文献
1) Ardlie KG, Kruglyak L, Seielstad M. Patterns of linkage disequilibrium in the human genome. Nat Rev Genet 2002 ; 3 : 299-309.
PubMed
2) Wang WY, et al. Genome-wide association studies : Theoretical and practical concerns. Nat Rev Genet 2005 ; 6 : 109-118.
PubMed
3) O'Donovan MC, et al. Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet 2008 ; 40 : 1053-1055.
PubMed
4) Stefansson H, et al. Large recurrent microdeletions associated with schizophrenia. Nature 2008 ; 455 : 232-236.
PubMed
5) Stefansson H, et al. Common variants conferring risk of schizophrenia. Nature 2009 ; 460 (7256) : 744-747.
PubMed
6) International Schizophrenia Consortium. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 2009 ; 460 (7256) : 748-752.
PubMed
7) Shi J, et al. Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature 2009 ; 460 (7256) : 753-757.
PubMed
P.145 掲載の参考文献
1) Li D, He L. Association study between the NMDA receptor 2B subunit gene (GRIN2B) and schizophrenia : A HuGE review and meta-analysis. Genet Med 2007 ; 9 : 4-8.
PubMed
2) Allen NC, et al. Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia : The SzGene database. Nat Genet 2008 ; 40 : 827-834.
PubMed
3) Itokawa M, et al. A microsatellite repeat in the promoter of the N-methyl-D-aspartate receptor 2A subunit (GRIN2A) gene suppresses transcriptional activity and correlates with chronic outcome in schizophrenia. Pharmacogenetics 2003 ; 13 : 271-278.
 
4) Harrison PJ, Owen MJ. Genes for schizophrenia? Recent findings and their pathophysiological implications. Lancet 2003 ; 361 : 417-419.
PubMed
5) Harrison PJ, Weinberger DR. Schizophrenia genes, gene expression, and neuropathology : On the matter of their convergence. Mol Psychiatry 2005 ; 10 : 40-68.
PubMed
6) Shi J, et al. Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature 2009 ; 460 : 753-757.
PubMed
7) Walsh T, et al. Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science 2008 ; 320 : 539-543.
PubMed
P.148 掲載の参考文献
1) Rapoport JL, et al. The neurodevelopmental model of schizophrenia : Update 2005. Mol Psychiatry 2005 ; 10 : 434-449.
PubMed
2) Fatemi SH, Folsom TD. The neurodevelopmental hypothesis of schizophrenia, revisited. Schizophr Bull 2009 ; 35 : 528-548.
PubMed
3) Cannon M, et al. Evidence for early-childhood, pandevelopmental impairment specific to schizophreniform disorder : Results from a longitudinal birth cohort. Arch Gen Psychiatry 2002 ; 59 : 449-456.
PubMed
4) Harrison PJ, Weinberger DR. Schizophrenia genes, gene expression, and neuropathology : On the matter of their convergence. Mol Psychiatry 2005 ; 10 : 40-68.
PubMed
5) DeLisi LE. The concept of progressive brain change in schizophrenia : Implications for understanding schizophrenia. Schizophr Bull 2008 ; 34 : 312-321.
PubMed
6) Hulshoff Pol HE, Kahn RS. What happens after the first episode? A review of progressive brain changes in chronically ill patients with schizophrenia. Schizophr Bull 2008 ; 34 : 354-366.
PubMed
7) 尾関祐二, 藤井久彌子. 統合失調症の分子病態研究. 脳と精神の医学. 2009 ; 20 : 347-353.
 
Rapoport JL, et al. The neurodevelopmental model of schizophrenia : Update 2005. Mol Psychiatry 2005 ; 10 : 434-449.
PubMed
Harrison PJ, Weinberger DR. Schizophrenia genes, gene expression, and neuropathology : On the matter of their convergence. Mol Psychiatry 2005 ; 10 : 40-68.
PubMed
DeLisi LE. The concept of progressive brain change in schizophrenia : Implications for understanding schizophrenia. Schizophr Bull 2008 ; 34 : 312-321.
PubMed
P.151 掲載の参考文献
1) Kunugi H, Lee KB, Nanko S. Cytogenetic findings in 250 schizophrenics : Evidence confirming an excess of the X chromosome aneuploidies and pericentric inversion of chromosome 9. Schizophr Res 1999 ; 40 : 43-47.
PubMed
2) Kirov G, et al. Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia. Hum Mol Genet 2008 ; 17 : 458-465.
PubMed
3) Mizuguchi T, et al. Microarray comparative genomic hybridization analysis of 59 patients with schizophrenia. J Hum Genet 2008 ; 53 : 914-919.
PubMed
4) International Schizophrenia Consortium Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature 2008 ; 455 : 237-241.
PubMed
5) Stefansson H, et al. Large recurrent microdeletions associated with schizophrenia. Nature 2008 ; 455 : 232-236.
PubMed
6) Need AC, et al. A genome-wide investigation of SNPs and CNVs in schizophrenia. PLoS Genet 2009 ; 5 : e1000373.
PubMed
Tam GW, et al. The role of DNA copy number variation in schizophrenia. Biol Psychiatry 2009 ; 66 : 1005-1012.
PubMed
Cook EH Jr, Scherer SW. Copy-number variations associated with neuropsychiatric conditions. Nature 2008 ; 455 : 919-923.
PubMed
P.154 掲載の参考文献
1) Goldberg AD, Allis CD, Bernstein E. Epigenetics : A landscape takes shape. Cell 2007 ; 128 : 635-638.
PubMed
2) Moore SC, Ausio J. Major role of the histones H3-H4 in the folding of the chromatin fiber. Biochem Biophys Res Commun 1997 ; 230 : 136-139.
PubMed
3) Fuchikami M, et al. Single immobilization stress differentially alters the expression profile of transcripts of the brain-derived neurotrophic factor (BDNF) gene and histone acetylation at its promoters in the rat hippocampus. Int J Neuropsychopharmacol 2008 ; 12 : 73-82.
PubMed
4) Tsankova NM, et al. Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat Neurosci 2006 ; 9 : 519-525.
 
5) Tsankova NM, et al. Histon modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures. J Neurosci 2004 ; 24 : 5603-5610.
PubMed
P.158 掲載の参考文献
1) Goldman D, Oroszi G, Ducci F. The genetics of addictions : Uncovering the genes. Nat Rev Genet 2005 ; 6 : 521-532.
PubMed
2) Heath AC, et al. Genetic and environmental contribution to alcohol dependence risk in a national twin sample : Consistency of findings in women and men. Psychol Med 1997 ; 27 : 1381-1396.
 
3) True WR, et al. Common genetic vulnerability for nicotine and alcohol dependence in men. Arch Gen Psychiatry 1999 ; 56 : 655-661.
PubMed
4) Ducci F, Goldman D. Genetic approaches to addiction : Genes and alcohol. Addiction 2008 ; 103 : 1414-1428.
PubMed
5) Fu Q, et al. Shared genetic risk of major depression, alcohol dependence, and marijuana dependence : Contribution of antisocial personality disorder in men. Arch Gen Psychiatry 2002 ; 59 : 1125-1132.
PubMed
6) Higuchi S, et al. Influence of genetic variations of ethanol-metabolizing enzymes on phenotypes of alcohol-related disorders. Ann NY Acad Sci 2004 ; 1025 : 472-480.
PubMed
7) Treutlein J, et al. Genome-wide association study of alcohol dependence. Arch Gen Psychiatry 2009 ; 66 : 773-784.
PubMed
8) Pandey SC, et al. Brain chromatin remodeling : A novel mechanism of alcoholism. J Neurosci 2008 ; 28 : 3729-3737.
PubMed
Strat YL, et al. Molecular genetics of alcohol dependence and related endophenotypes. Curr Genomics 2008 ; 9 : 444-451.
PubMed
Kalsi G, et al. Unraveling the molecular mechanisms of alcohol dependence. Trends Genet 2009 ; 25 : 49-55.
PubMed
Gelernter J, Kranzler HR. Genetics of alcohol dependence. Hum Genet 2009 ; 126 : 91-99.
PubMed
P.161 掲載の参考文献
1) Lintas C, Persico AM. Autistic phenotypes and genetic testing : State-of-the-art for the clinical geneticist. J Med Genet 2009 : 46 ; 1-8.
PubMed
2) Garber K. Autism's cause may reside in abnormalities at the synapse. Science 2007 ; 317 : 190-191.
PubMed
3) Soderstrom H, et al. Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism. Nat Genet 2003 ; 34 : 27-29.
PubMed
4) Durand CM, et al. Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders. Nat Genet 2007 ; 39 : 25-27.
PubMed
5) The Autism Genome Project Consortium. Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet 2007 ; 39 : 319-328.
PubMed
6) Sudhof TC. Neuroligins and neurexins link synaptic function to cognitive disease. Nature 2008 ; 455 : 903-911.
PubMed
Abrahams BS, Geschwind DH. Advances in autism genetics : On the threshold of a new neurobiology. Nat Rev Genet 2008 ; 9 : 341-355.
PubMed
Freitag CM. The genetics of autistic disorders and its clinical relevance : A review of the literature. Mol Psychiatry 2007 ; 12 : 2-22.
PubMed
P.163 掲載の参考文献
1) Carninci P, et al. The transcriptional landscape of the mammalian genome. Science 2005 ; 309 (5740) : 1559-1563.
PubMed
2) Tomari Y, Zamore PD. Perspective : Machines for RNAi. Genes Dev 2005 ; 19 (5) : 517-529.
 
3) Perkins DO, et al. microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaff ective disorder. Genome Biol 2007 ; 8 (2) : R27.
 
4) Abu-Elneel K, et al. Heterogeneous dysregulation of microRNAs across the autism spectrum. Neurogenetics 2008 ; 9 (3) : 153-161.
PubMed
Hunsberger JG, et al. MicroRNAs in mental health : From biological underpinnings to potential therapies. Neuromolecular Med 2009 ; 11 (3) : 173-182.
PubMed
Kosik KS. The neuronal microRNA system. Nat Rev Neurosci 2006 ; 7 (12) : 911-920.
PubMed
P.166 掲載の参考文献
1) Takao K, Yamasaki N, Miyakawa T. Impact of brainbehavior phenotyping of genetically-engineered mice on research of neuropsychiatric disorders. Neurosci Res 2007 ; 58 : 124-132.
PubMed
2) Crawley JN. What's Wrong With My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice, 2nd edition. Hoboken, New Jersey : John Wiley & Liss ; 2007.
 
3) Yamasaki N, et al. Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders. Mol Brain 2008 ; 1 : 6.
PubMed
4) Li W, et al. Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice. Proc Natl Acad Sci U S A 2007 ; 104 : 18280-18285.
PubMed
5) Takao K, et al. Impaired long-term memory retention and working memory in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia. Mol Brain 2008 ; 1 : 11.
PubMed
6) Stefansson H, et al. Common variants conferring risk of schizophrenia. Nature 2009 ; 460 : 744-747.
PubMed
7) Purcell SM, et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 2009 ; 460 : 748-752.
PubMed
8) Shi J, et al. Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature 2009 ; 460 : 753-757.
PubMed
森寿, ほか (編). 脳神経科学イラストレイテッド, 改訂第2版. 東京 : 羊土社 ; 2006.
 
小出剛 (編). マウス実験の基礎知識. 東京 : オーム社 ; 2009.
 
Crawley JN. What's Wrong With My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice, 2nd edition. Hoboken, New Jersey : John Wiley & Liss ; 2007.
 
P.168 掲載の参考文献
1) 神谷篤, 北畠康司, 澤明. 脳の発達異常と精神疾患. BRAIN and NERVE 2008 ; 60 (4) : 445-452.
 
2) Wilson SW, Rubenstein JL. Induction and dorsoventral patterning of the telencephalon. Neuron 2000 ; 28 : 641-651.
PubMed
3) Aizawa H, et al. Temporally regulated asymmetric neurogenesis causes left-right difference in the zebrafish habenular structures. Dev Cell 2007 ; 12 : 87-98.
PubMed
4) Soma M, et al. Development of the mouse amygdala as revealed by enhanced green fluorescent protein gene transfer by means of in utero electroporation. J Comp Neurol 2009 ; 513 : 113-128.
PubMed
岡本仁. 脳の基本設計図と心の進化, 多様化, 障害. 岡本仁 (編). 脳の発生と発達. 東京 : 東京大学出版会 ; 2008. pp5-38.
 
P.170 掲載の参考文献
1) Burgoyne R. The Neuronal Cytoskeleton. New York : Wiley-Liss ; 1991.
 
2) Pannese E III. Shape and size of neurons. In : Neurocytology. Stuttgart : Georg Thieme Verlag ; 1994. p.11.
 
3) Alberts B, et al. Chapter 16 : The cytoskeleton. In : Molecular Biology of the Cell. 5th edition. New York : Garland Science ; 2008.
 
4) Dent EW, Gertler FB. Cytoskeletal dynamics and transport in growth cone motility and axon guidance. Neuron 2003 ; 40 : 209-227.
PubMed
5) Bulic B, et al. Development of tau aggregation inhibitors for Alzheimer's disease. Angewandte Chemie 2009 ; 48 : 1740-1752.
PubMed
6) Hirokawa N, Noda Y. Intracellular transport and kinesin superfamily proteins, KIFs : Structure, function, and dynamics. Physiol Rev 2008 ; 88 : 1089-1118.
PubMed
7) Cole NB, et al. Golgi dispersal during microtubule disruption : Regeneration of Golgi stacks at peripheral endoplasmic reticulum exit sites. Mol Biol Cell 1996 ; 7 : 631-650.
PubMed
Pollard TD, Earnshaw WC. Cytoskeleton and Cellular Motility. In : Cell Biology. Philadelphia : Saunders ; 2002. pp.551-670.
 
Burgoyne R. The Neuronal Cytoskeleton. New York : Wiley-Liss ; 1991.
 
Alberts B, et al. Chapter 16 : The cytoskeleton. In : Molecular Biology of the Cell. 5th edition. New York : Garland Science ; 2008.
 
P.173 掲載の参考文献
1) Altar CA, et al. Electroconvulsive seizures regulate gene expression of distinct neurotrophic signaling pathways. J Neurosci 2004 ; 24 : 2667-2677.
PubMed
2) Kato N. Neurophysiological mechanisms of electroconvulsive therapy for depression. Neurosci Res 2009 ; 64 : 3-11.
PubMed
3) Fagni L, Worley PF, Ango F. Homer as both a scaffold and transduction molecule. Sci STKE 2002 ; 137 : RE8.
PubMed
4) Bajbouj M, et al. Evidence for impaired cortical inhibition in patients with unipolar major depression. Biol Psychiatry 2006 ; 59 : 395-400.
PubMed
5) Sanacora G, et al. Increased cortical GABA concentrations in depressed patients receiving ECT. Am J Psychiatry 2003 ; 160 : 577-579.
PubMed
P.175 掲載の参考文献
1) Kyriakopouros M, et al. Diffusion tensor imaging in schizophrenia. Eur Psychiatry 2009 ; 23 : 255-273.
 
2) Bernstein HG, Steiner J, Bogerts B. Glial cells in schizophrenia : Pathological significance and possible consequences for therapy. Expert Rev Neurother 2009 ; 9 (7) : 1059-1071.
PubMed
3) Karoutzou G, Emrich HM, Dietrich DE. The myelinpathogenesis puzzle in schizophrenia : A literature review. Mol Psychiatry 2008 ; 13 : 245-260.
PubMed
4) Fields RD. White matter in learning, cognition and psychiatric disorders. Trends Neurosci 2008 ; 31 (7) : 361-370.
PubMed
5) Monji A, Kato T, Kanba S. Cytokines and schizophrenia : Microglial hypothesis of schizophrenia. Psychiatry Clin Neurosci 2009 ; 63 : 257-265.
PubMed
P.177 掲載の参考文献
1) Oberheim NA, et al. Uniquely hominid features of adult human astrocytes. J Neurosci 2009 ; 29 (10) : 3276-3287.
PubMed
2) Hirase H, et al. Calcium dynamics of cortical astrocytic networks in vivo. PLoS Biol 2004 ; 2 (4) : E96.
PubMed
3) Takata N, Hirase H. Cortical layer 1 and layer 2/3 astrocytes exhibit distinct calcium dynamics in vivo. PLoS ONE 2008 ; 3 (6) : e2525.
PubMed
4) Wang X, et al. Astrocytic Ca2+ signaling evoked by sensory stimulation in vivo. Nat Neurosci 2006 ; 9 (6) : 816-823.
PubMed
5) Takano T, et al. Astrocyte-mediated control of cerebral blood flow. Nat Neurosci 2006 ; 9 (2) : 260-267.
PubMed
6) Winship IR, Plaa N, Murphy TH. Rapid astrocyte calcium signals correlate with neuronal activity and onset of the hemodynamic response in vivo. J Neurosci 2007 ; 27 (23) : 6268-6272.
PubMed
Iadecola C, Nedergaard M. Glial regulation of the cerebral microvasculature. Nat Neurosci 2007 ; 10 (11) : 1369-1376.
PubMed
Oberheim NA, et al. Astrocytic complexity distinguishes the human brain. Trends Neurosci 2006 ; 29 (10) : 547-553.
PubMed
P.179 掲載の参考文献
1) Hanisch UK, Kettenmann H. Microglia : Active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci 2007 ; 10 : 1387-1394.
PubMed
2) Steiner J, et al. Immunological aspects in the neurobiology of suicide : Elevated microglial density in schizophrenia and depression is associated with suicide. J Psychiatr Res 2008 ; 42 : 151-157.
PubMed
3) van Berckel BN, et al. Microglia activation in recentonset schizophrenia : A quantitative (R) -[11C] PK 11195 positron emission tomography study. Biol Psychiatry 2008 ; 64 : 820-822.
PubMed
4) Monji A, Kato T, Kanba S. Cytokines and schizophrenia : Microglia hypothesis of schizophrenia. Psychiatry Clin Neurosci 2009 ; 63 : 257-265.
PubMed
5) Miyaoka T, et al. Minocycline as adjunctive therapy for schizophrenia : An open-label study. Clin Neuropharmacol 2008 ; 31 : 287-292.
PubMed
6) Akhondzadeh S, et al. Celecoxib as adjunctive therapy in schizophrenia : A double-blind, randomized and placebo-controlled trial. Schizophr Res 2007 ; 90 : 179-185.
PubMed
7) Kato T, et al. Inhibitory eff ects of aripiprazole on interferon-gamma-induced microglial activation via intracellular Ca2+ regulation in vitro. J Neurochem 2008 ; 106 : 815-825.
 
8) Kato T, et al. Risperidone significantly inhibits interferon-gamma-induced microglial activation in vitro. Schizophr Res 2007 ; 92 : 108-115.
PubMed
9) Schiavone S, et al. Involvement of NOX2 in the development of behavioral and pathologic alterations in isolated rats. Biol Psychiatry 2009 ; 66 : 384-392.
PubMed
Hanisch UK, Kettenmann H. Microglia : Active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci 2007 ; 10 : 1387-1394.
PubMed
Monji A, Kato T, Kanba S. Cytokines and schizophrenia : Microglia hypothesis of schizophrenia. Psychiatry Clin Neurosci 2009 ; 63 : 257-265.
PubMed
P.182 掲載の参考文献
1) Miller G. Neuroscience. The dark side of glia. Science 2005 ; 308 : 778-781.
PubMed
2) Burnstock G. Pathophysiology and therapeutic potential of purinergic signaling. Pharmacol Rev 2006 ; 58 : 58-86.
PubMed
3) Tsuda M, et al. P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury. Nature 2003 ; 424 : 778-783.
PubMed
4) Coull JA, et al. BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain. Nature 2005 ; 438 : 1017-1021.
PubMed
5) Inoue K, et al. The role of nucleotides in the neuronglia communication responsible for the brain functions. J Neurochem 2007 ; 102 : 1447-1458.
PubMed
6) Tsuda M, et al. IFN-γ receptor signaling mediates spinal microglia activation driving neuropathic pain. Pro Natl Acad Sci USA 2009 ; 106 : 8032-8037.
 
P.186 掲載の参考文献
1) 斉藤真一ほか. 細胞内シグナル伝達経路. 日本臨床精神神経薬理学会専門医制度委員会 (編). 臨床精神神経薬理学テキスト. 東京 : 星和書店 ; 2006. pp20-24.
 
2) 宇井理生. 第I章 神経情報伝達のメカニズム. 樋口輝彦ほか (編). 臨床精神薬理ハンドブック. 東京 : 医学書院 ; 2003.
 
3) Miller RJ. The control of neuronal Ca2+ homeostasis. Prog Neurobiol 1991 ; 37 (3) : 255-285.
PubMed
4) Soderling TR. CaM-kinases : Modulators of synaptic plasticity. Curr Opin Neurobiol, 2000 ; 10 (3) : 375-380.
PubMed
5) Gould T, Gray NA, Manji HK. The cellular neurobiology of severe mood disorder and anxiety disorders : Implications for the development of novel therapeutics. In : Charney DS (ed). Molecular Neurobiology for the Clinician, Review of Psychiatry Series. American Psychiatric Publishing ; 2003.
 
6) Barry J, Liegeois CM, Janoshazi A. Protein kinase C as a peripheral biomarker for Alzheimer's disease. Exp Gerontol 2010 ; 45 : 64-69.
PubMed
7) Davies SP, et al. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J. 2000 ; 351 (Pt 1) : 95-105.
 
8) Woo-Yang Kim, et al. GSK-3 is a master regulator of neural progenitor homeostasis. Nat Neurosci 2009 ; 12 : 1390-1397.
PubMed
9) Greengard P. The neurobiology of slow synaptic transmission. Science 2001 ; 294 (5544) : 1024-1030.
PubMed
P.188 掲載の参考文献
1) Artavanis-Tsakonas S, Rand MD, Lake RJ. Notch signaling : Cell fate control and signal integration in development. Science 1999 ; 284 : 770-776.
PubMed
2) Chiba S. Notch signaling in stem cell systems. Stem Cells 2006 ; 24 : 2437-2447.
PubMed
3) Yoon K, Gaiano N. Notch signaling in the mammalian central nervous system, insights from mouse mutants. Nat Neurosci 2005 ; 8 : 709-715.
PubMed
4) Gage FH. Mammalian neural stem cells. Science 2000 ; 287 : 1433-1438.
PubMed
5) Ming G, Song H. Adult neurogenesis in the mammalian central nervous system. Annu Rev Neurosci 2005 ; 28 : 223-250.
PubMed
6) Higashi M, et al. Mood stabilizing drugs expand the neural stem cell pool in the adult brain through activation of Notch signaling. Stem Cells 2008 ; 26 : 1758-1767.
PubMed
Pittenger C, Duman RS. Stress, depression, and neuroplasticity : A convergence of mechanisms. Neuropsychopharmacology 2008 ; 33 : 88-109.
PubMed
等誠司. 気分障害の病態解明を目指した神経幹細胞研究. Jpn J Neuropsychopharmacol 2008 ; 28 : 189-194.
 
P.191 掲載の参考文献
1) Kawaguchi Y, Kondo S. Parvalbumin, somatostatin and cholecystokinin as chemical markers for specific GABAergic interneuron types in the rat frontal cortex. J Neurocytol 2002 ; 31 : 277-287.
PubMed
2) Lewis DA, Hashimoto T, Volk DW. Cortical inhibitory neurons and schizophrenia. Nat Rev Neurosci 2005 ; 6 : 312-324.
PubMed
3) Hashimoto T, et al. Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia. Molecular Psychiatry 2008 ; 13 : 147-161.
PubMed
4) Hashimoto T, et al. Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia. Am J Psychiatry 2008 ; 165 : 479-489.
PubMed
5) Bartos M, Vida I, Jonas P. Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks. Nat Rev Neurosci 2007 ; 8 : 45-56.
PubMed
6) Freis P. Neuronal gamma-band synchronization as a fundamental process in cortical computation. Annu Rev Neurosci 2009 ; 32 : 209-224.
 
7) Uhlhaas PJ, Singer W. Abnormal neural oscillations and synchrony in schizophrenia. Nat Rev Neurosci 2010 ; 11 : 100-113.
PubMed
Lewis DA, Hashimoto T, Volk DW. Cortical inhibitory neurons and schizophrenia. Nat Rev Neurosci 2005 ; 6 : 312-324.
PubMed
Uhlhaas PJ, Singer W. Abnormal neural oscillations and synchrony in schizophrenia. Nat Rev Neurosci 2010 ; 11 : 100-113.
PubMed
P.194 掲載の参考文献
1) ニック・レーン (著). 斉藤隆央 (訳). ミトコンドリアが進化を決めた. 東京 : みすず書房 ; 2007.
 
2) Kato T. Role of mitochondrial DNA in calcium signaling abnormality in bipolar disorder. Cell Calcium 2008 ; 44 : 92-102.
PubMed
3) Yoshida H, et al. XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 2001 ; 107 : 881-891.
PubMed
4) Hayashi T, Su TP. Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca2+ signaling and cell survival. Cell 2007 ; 131 : 596-610.
PubMed
5) Kasahara T, et al. Mice with neuron-specific accumulation of mitochondrial DNA mutations show mood disorder-like phenotypes. Mol Psychiatry 2006 ; 11 : 577-593.
PubMed
6) Kakiuchi C, et al. Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder. Nat Genet 2003 ; 35 : 171-175.
PubMed
7) 加藤忠史. XBP1と双極性障害. 実験医学 2008 ; 26 : 2390-2394.
Medical*Online
8) 笠原和起, 加藤忠史. 双極性障害におけるミトコンドリア機能障害. 脳と精神の医学 2008 ; 19 : 107-115.
 
ニック・レーン (著). 斉藤隆央 (訳). ミトコンドリアが進化を決めた. 東京 : みすず書房 ; 2007.
 
加藤忠史. XBP1と双極性障害. 実験医学 2008 ; 26 : 2390-2394.
Medical*Online
笠原和起, 加藤忠史. 双極性障害におけるミトコンドリア機能障害. 脳と精神の医学 2008 ; 19 : 107-115.
 
P.197 掲載の参考文献
1) Inestrosa NC, Dinamarca MC, Alvarez A. Amyloidcholinesterase interactions. Implications for alzheimer's disease. FEBS J 2008 ; 275 : 625-632.
PubMed
2) Glabe CG. Structural classification of toxic amyloid oligomers. J Biol Chem 2008 ; 283 : 29639-29643.
PubMed
3) Walsh DM, et al. Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates. J Biol Chem 1999 ; 274 : 25945-25952.
PubMed
4) Hardy J. The amyloid hypothesis for Alzheimer's disease : A critical reappraisal. J Neurochem 2009 ; 110 (4) : 1129-1134.
PubMed
5) Holmes C, et al. Long-term effects of A beta 42 immunisation in Alzheimer's disease : Follow-up of a randomised, placebo-controlled phase I trial. Lancet 2008 ; 372 : 216-223.
PubMed
6) Gendron TF, Petrucelli L. The role of tau in neurodegeneration. Mol Neurodegener 2009 ; 4 : 13.
PubMed
7) Iqbal K, et al. Mechanisms of tau-induced neurodegeneration. Acta Neuropathol 2009 ; 118 : 53-69.
PubMed
8) Ludolph AC, et al. Tauopathies with parkinsonism : Clinical spectrum, neuropathologic basis, biological markers, and treatment options. Eur J Neurol 2009 ; 16 : 297-309.
PubMed
9) Bisaglia M, Mammi S, Bubacco L. Structural insights on physiological functions and pathological effects of alpha-synuclein. FASEB J 2009 ; 23 : 329-340.
PubMed
10) Lippa CF, et al. Dlb and pdd boundary issues : Diagnosis, treatment, molecular pathology, and biomarkers. Neurology 2007 ; 68 : 812-819.
PubMed
11) Hegde AN, Upadhya SC. The ubiquitin-proteasome pathway in health and disease of the nervous system. Trends Neurosci 2007 ; 30 : 587-595.
PubMed
12) Neumann M. Molecular neuropathology of tdp-43 proteinopathies. Int J Mol Sci 2009 ; 10 : 232-246.
PubMed
13) Neumann M, et al. Tdp-43 proteinopathy in frontotemporal lobar degeneration and amyotrophic lateral sclerosis : Protein misfolding diseases without amyloidosis. Arch Neurol 2007 ; 64 : 1388-1394.
PubMed
Inestrosa NC, Dinamarca MC, Alvarez A. Amyloidcholinesterase interactions. Implications for alzheimer's disease. FEBS J 2008 ; 275 : 625-632.
PubMed
Hardy J. The amyloid hypothesis for Alzheimer's disease : A critical reappraisal. J Neurochem 2009 ; 110 (4) : 1129-1134.
PubMed
Gendron TF, Petrucelli L. The role of tau in neurodegeneration. Mol Neurodegener 2009 ; 4 : 13.
PubMed
Ludolph AC, et al. Tauopathies with parkinsonism : Clinical spectrum, neuropathologic basis, biological markers, and treatment options. Eur J Neurol 2009 ; 16 : 297-309.
PubMed
Neumann M, et al. Tdp-43 proteinopathy in frontotemporal lobar degeneration and amyotrophic lateral sclerosis : Protein misfolding diseases without amyloidosis. Arch Neurol 2007 ; 64 : 1388-1394.
PubMed
P.200 掲載の参考文献
1) Olds J, Milner P. Positive reinforcement produced by electrical stimulation on septal area and other regions of the rat brain. J Comp Physiol Psychol 1954 ; 47 : 419-427.
 
2) Diamond I, Gordon AS. Cellular and molecular neuroscience of alcoholism. Physiol Rev 1997 ; 77 : 1-20.
PubMed
3) Sohma H, et al. Quantitative reduction of type I adenylyl cyclase in human alcoholics. Biochim Biophys Acta 1999 ; 1454 : 11-18.
PubMed
4) Davis MI. Ethanol-BDNF interactions : Still more questions than answers. Pharmacol Ther 2008 ; 118 : 36-57.
PubMed
5) White AM, Matthews DB, Best PJ. Ethanol, memory, and hippocampal function : A review of recent findings. Hippocampus 2000 ; 10 : 88-93.
PubMed
6) Crews FT, Nixon K. Mechanism of neurodegeneration and regeneration in alcoholism. Alcohol Alcohol 2009 ; 44 : 115-127.
PubMed
7) Guerrini I, Thomson AD, Gurling HD. The importance of alcohol misuse, malnutrition and genetic susceptibility on brain growth and plasticity. Neurosci Biobehav Rev 2007 ; 31 : 212-220.
PubMed
8) Yoshinaga T, et al. Neural stem cell transplantation in a model of fetal alcohol effects. J Neural Transm Suppl 2007 ; 72 : 331-337.
 
「アルコールと健康」研究会 (編). お酒の健康科学. 京都 : 金芳堂 ; 1996.
 
Eckardt MJ, et al. Effects of moderate alcohol consumption on the central nervous system. Alcohol Clin Exp Res 1998 ; 22 : 998-1040.
PubMed
Vengeliene V, et al. Neuropharmacology of alcohol addiction. Br J Pharmacol 2008 ; 154 : 299-315.
PubMed
P.202 掲載の参考文献
1) Young LJ, Wang Z, Insel TR. Neuroendocrine bases of monogamy. Trends Neurosci 1998 ; 21 : 71-75.
PubMed
2) Modahl C, et al. Plasma oxytocin levels in autistic children. Biol Psychiatry 1998 ; 43 : 270-277.
PubMed
3) Lerer E, et al. Association between the oxytocin receptor (OXTR) gene and autism : Relationship to Vineland Adaptive Behavior Scales and cognition. Mol Psychiatry 2008 ; 13 : 980-988.
PubMed
4) Ferguson JN, et al. Social amnesia in mice lacking the oxytocin gene. Nat Genet 2000 ; 25 : 284-288.
PubMed
5) Takayanagi Y, et al. Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice. Proc Natl Acad Sci U S A 2005 ; 102 : 16096-16101.
PubMed
6) Jin D, et al. CD38 is critical for social behaviour by regulating oxytocin secretion. Nature 2007 ; 446 : 41-45.
PubMed
山未英典. 社会性障害の脳神経基盤. 臨床精神医学 2007 ; 36 : 987-992.
 
Heinrichs M, et al. Oxytocin, vasopressin, and human social behavior Front Neuroendocrinol 2009 ; 30 : 548-557.
PubMed

III 精神薬理学

P.205 掲載の参考文献
1) Pierce RC, Kumaresan V. The mesolimbic dopamine system : The final common pathway for the reinforcing effect of drugs of abuse? Neurosci Biobehav Rev 2006 ; 30 (2) : 215-238.
PubMed
2) Gether U, et al. Neurotransmitter transporters : Molecular function of important drug targets. Trends Pharmacol Sci 2006 ; 27 (7) : 375-383.
PubMed
3) Kuhar MJ, Ritz MC, Boja JW. The dopamine hypothesis of the reinforcing properties of cocaine. Trends Neurosci 1991 ; 14 (7) : 299-302.
PubMed
4) Kalivas PW, Sorg BA, Hooks MS. The pharmacology and neural circuitry of sensitization to psychostimulants. Behav Pharmacol 1993 ; 4 (4) : 315-334.
PubMed
5) Koob GF, Le Moal M. Drug addiction, dysregulation of reward, and allsostasis. Neuropsychopharmacology 2001 ; 24 (2) : 97-129.
PubMed
Hyman SE, Malenka RC, Nestler EJ. Neural mechanisms of addiction : The role of reward-related learning and memory. Annu Rev Neurosci 2006 ; 29 : 565-598.
PubMed
Phillips TJ, Kamens HM, Wheeler JM. Behavioral genetic contributions to the study of addiction-related amphetamine effects. Neurosci Biobehav Rev 2008 ; 32 (4) : 707-759.
 
Koob GF. Neurobiological substrates for the dark side of compulsivity in addiction. Neuropharmacology 2009 ; 56 Suppl 1 : 18-31.
 
P.208 掲載の参考文献
1) 小高文聰, 須原哲也. 神経伝達物質受容体の画像化. 福田正人 (編). 専門医のための精神科臨床リミュエール 2 精神疾患と脳画像. 東京 : 中山書店 ; 2008. pp175-182.
 
2) Suhara T, et al. Extrastriatal dopamine D2 receptor density and affinity in the human brain measured by 3D PET. Int J Neuropsychopharmacol 1999 ; 2 (2) : 73-82.
PubMed
3) Suhara T, et al. Decreased dopamine D2 receptor binding in the anterior cingulate cortex in schizophrenia. Arch Gen Psychiatry 2002 ; 59 (1) : 25-30.
PubMed
4) Yasuno F, et al. Low dopamine d (2) receptor binding in subregions of the thalamus in schizophrenia. Am J Psychiatry 2004 ; 161 (6) : 1016-1022.
PubMed
5) Okubo Y, et al. Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET. Nature 1997 ; 385 (6617) : 634-636.
PubMed
6) Nozaki S, et al. Regional dopamine synthesis in patients with schizophrenia using L- [beta-11C] DOPA PET. Schizophr Res 2009 ; 108 (1-3) : 78-84.
 
7) Arakawa R, et al. Increase in thalamic binding of [(11) C] PE2I in patients with schizophrenia : A positron emission tomography study of dopamine transporter. J Psychiatr Res 2009 ; 43 : 1219-23.
PubMed
須原哲也ほか, 精神疾患の病態解明と客観的治療評価に向けたPETイメージング研究. 最新医学 2010 ; 65 : 122-153.
 
P.211 掲載の参考文献
1) 西川徹. 脳の内在性D-セリンの代謝・機能と精神神経疾患における意義. 生化学 2008 ; 80 : 267-276.
 
2) Inoue R, et al. NMDA- and beta-amyloid 1-42-induced neurotoxicity is attenuated in serine racemase knockout mice. J Neurosci 2008 ; 28 : 14486-14491.
PubMed
3) Verrall L, et al. The neurobiology of D-amino acid oxidase and its involvement in schizophrenia. Mol Psychiatry 2010 ; 15 (2) : 122-137.
PubMed
4) Oliet SH, Mothet JP. Regulation of N-methyl-D-aspartate receptors by astrocytic D-serine. Neuroscience 2009 ; 158 : 275-283.
 
5) 西川徹. 統合失調症とグルタミン酸伝達系. 精神神経学雑誌 2009 ; 111 : 859-867.
 
6) Labrie V, et al. Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model. Hum Mol Genet 2009 ; 18 : 3227-3243.
 
7) Sacchi S, et al. pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase : Effect on schizophrenia susceptibility. J Biol Chem 2008 ; 283 : 22244-22256.
PubMed
8) Tuominen HJ, Tiihonen J, Wahlbeck K. Glutamatergic drugs for schizophrenia : A systematic review and meta-analysis. Schizophr Res 2005 ; 72 : 225-234.
PubMed
P.213 掲載の参考文献
1) Healy D, McMonagle T. The enhancement of social functioning as a therapeutic principle in the management of depression. J Psychopharmacol 1997 ; 11 (4 suppl) : S25-S31.
 
2) Schildkraut JJ. The catecholamine hypothesis of affective disorder : A review of supporting evidence. Am J Psychiatry 1965 ; 122 : 509-522.
 
3) Lester D. The concentration of neurotransmitter metabolites in the cerebrospinal fluid of suicidal individuals : A meta-analysis. Pharmacopsychiatry 1995 ; 28 : 45-50.
PubMed
4) Taylor MJ, et al. Early onset of selective serotonin reuptake inhibitor antidepressant action : Systematic review and meta-analysis. Arch Gen Psychiatry 2006 ; 63 : 1217-1223.
PubMed
5) Belmaker RH, Agam G. Major depressive disorder. N Engl J Med 2008 ; 3 : 358 : 55-68.
 
6) Meyer JH, et al. Elevated monoamine oxidase a levels in the brain : An explanation for the monoamine imbalance of major depression. Arch Gen Psychiatry 2006 ; 63 : 1209-1216.
 
7) Lambert G, et al. Reduced brain norepinephrine and dopamine release in treatment-refractory depressive illness : Evidence in support of the catecholamine hypothesis of mood disorders. Arch Gen Psychiatry 2000 ; 57 : 787-793.
PubMed
P.216 掲載の参考文献
1) Goodwin FK, Jamison KR. Protein kinase C in the pathophysiology of recurrent mood disorders. In : Manic-Depressive Illness : Bipolar Disorders and Recurrent Depression, 2nd edition. New York : Oxford University Press ; 2007. pp548-550.
 
2) Quiroz JA, et al. Mitochondrially mediated plasticity in the pathophysiology and treatment of bipolar disorder. Neuropsychopharmacology 2008 ; 33 : 2551-2565.
PubMed
3) 加藤忠史. 双極性障害の病態生理. 樋口輝彦, 神庭重信 (編). 双極性障害の治療スタンダード. 東京 : 星和書店 ; 2002. pp15-24.
 
4) Hahn CG, et al. Aberrant intracellular calcium signaling in olfactory neurons from patients with bipolar disorder. Am J Psychiatry 2005 ; 162 : 616-618.
PubMed
5) Suzuki K, et al. Serotonin-induced platelet intracellular calcium mobilization in various psychiatric disorders : Is it specific to bipolar disorder? J Affect Disord 2001 ; 64 : 291-296.
PubMed
6) Kusumi I, et al. Treatment response in depressed patients with enhanced Ca mobilization stimulated by serotonin. Neuropsychopharmacology 2000 ; 23 : 690-696.
PubMed
Goodwin FK, Jamison KR. Protein kinase C in the pathophysiology of recurrent mood disorders. In : Manic-Depressive Illness : Bipolar Disorders and Recurrent Depression, 2nd edition. New York : Oxford University Press ; 2007. pp548-550.
 
Quiroz JA, et al. Mitochondrially mediated plasticity in the pathophysiology and treatment of bipolar disorder. Neuropsychopharmacology 2008 ; 33 : 2551-2565.
PubMed
加藤忠史. 双極性障害の病態生理. 樋口輝彦, 神庭重信 (編). 双極性障害の治療スタンダード. 東京 : 星和書店 ; 2002. pp15-24.
 
Hahn CG, et al. Aberrant intracellular calcium signaling in olfactory neurons from patients with bipolar disorder. Am J Psychiatry 2005 ; 162 : 616-618.
PubMed
P.218 掲載の参考文献
1) Berridge MJ, Downes CP, Hanley MR. Neural and developmental actions of lithium : A unifying hypothesis. Cell 1989 ; 59 : 411-419.
PubMed
2) Harwood AJ. Lithium and bipolar disorder : The inositol depletion hypothesis revisited. Mol Psychiatry 2005 ; 10 : 117-126.
PubMed
3) Ohnishi T, et al. A promoter haplotype of the inositol monophosphatase 2 (IMPA2) gene at 18p11.2 confers a possible risk for bipolar disorder by enhancing transcription. Neuropsychopharmacology 2007 ; 32 : 1727-1737.
PubMed
4) Baum AE, et al. A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder. Mol Psychiatry 2008 ; 13 : 197-207.
PubMed
5) Gould TD, Manji HK. Glycogen synthase kinase 3 : A putative molecular target for lithium mimetic drugs. Neuropsychopharmacology 2005 ; 30 : 1223-1237.
PubMed
加藤忠史. 双極性障害-躁うつ病の分子病理と治療戦略. 東京 : 医学書院 ; 1999.
 
寺尾岳. 21世紀のリチウム療法. 東京 : 新興医学出版社 ; 2006.
 
ケイ・ジャミソン (著), 田中啓子 (訳). 躁うつ病を生きる-わたしはこの残酷で魅惑的な病気を愛せるか? . 東京 : 新曜社 ; 1998.
 
P.221 掲載の参考文献
Nutt DJ, Malizia AL. New insights into the role of the GABA (A) -benzodiazepine receptor in psychiatric disorder. Br J Psychiatry 2001 ; 179 : 390-396.
 
Roy-Byrne PP. The GABA-benzodiazepine receptor complex : Structure, function, and role in anxiety. J Clin Psychiatry 2005 ; 66 (suppl 2) : 14-20.
 
Mohler H. GABAA receptor diversity and pharmacology. Cell Tissue Res 2006 ; 326 : 505-516.
PubMed
Reynolds DS. The value of genetic and pharmacological approaches to understanding the complexities of GABAA receptor subtype functions : The anxiolytic effects of benzodiazepines. Pharmacol Biochem Behav 2008 ; 90 : 37-42.
PubMed
P.224 掲載の参考文献
1) Bourin M, Baker GB, Bradwejn J. Neurobiology of panic disorder. J Psychosom Res 1998 ; 44 : 163-180.
PubMed
2) Maron E, Shlik J. Serotonin function in panic disorder : Important, but why? Neuropsychopharmacology 2006 ; 31 : 1-11.
PubMed
3) Gorman JM, et al. Neuroanatomical hypothesis of panic disorder, revised. Am J Psychiatry 2000 ; 157 : 493-505.
PubMed
穐吉條太郎. 神経化学・神経薬理学的仮説. 竹内龍雄 (編). パニック障害. 大阪 : 最新医学社 ; 2006. pp73-79.
 
越野好文. 薬物療法. 熊野宏昭ほか (編). パニック障害ハンドブック. 東京 : 医学書院 ; 2008. pp60-74.
 
P.227 掲載の参考文献
1) Baulieu EE, Robel P, Schumacher M. Neurosteroids : Beginning of the story. Int Rev Neurobiol 2001 ; 46 : 1-32.
PubMed
2) Charalampopoulos I, et al. Neurosteroids as modulators of neurogenesis and neuronal survival. Trends Endocrinol Metab 2008 ; 19 : 300-306.
 
3) Strous RD, Maayan R, Weizman A. The relevance of neurosteroids to clinical psychiatry : From the laboratory to the bedside. Eur Neuropsychopharmacol 2006 ; 16 : 155-169.
 
4) Girdler SS, Klatzkin R. Neurosteroids in the context of stress : Implications for depressive disorders. Pharmacol Ther 2007 ; 116 : 125-139.
PubMed
5) Strous RD, et al. Dehydroepiandrosterone (DHEA) augmentation in the management of negative, depressive, and anxiety symptoms in schizophrenia. Arch Gen Psychiatry 2003 ; 60 : 133-141.
PubMed
Belelli D, Lambert JJ. Neurosteroids : Endogenous of the GABAA receptor. Nat Rev Neurosci 2005 ; 6 : 565-575.
PubMed
Mellon SH, Griffin LD. Neurosteroids : Biochemistry and clinical significance. Trends Endocrinol Metab 2002 ; 13 : 35-43.
PubMed
Rupprecht R. Neuroactive steroids : Mechanisms of action and neuropsychopharmacological properties. Psychoneuroendocrinology 2003 ; 28 : 139-168.
PubMed
P.230 掲載の参考文献
1) Watanabe T, Yanai K. Studies on functional roles of the histaminergic neuron system by using pharmacological agents, knockout mice and positron emission tomography. Tohoku J Exp Med 2001 ; 195 : 197-217.
PubMed
2) Haas H, Panula P. The role of histamine and the tuberomammillary nucleus in the nervous system. Nat Rev Neurosci 2003 ; 4 (2) : 121-130.
PubMed
3) Haas HL, Sergeeva OA, Selbach O. Histamine in the nervous system. Physiol Rev 2008 ; 88 (3) : 1183-1241.
PubMed
4) 裏出良博. 睡眠・覚醒と視床下部. Clinical Neuroscience 2001 ; 19 (10) : 1111-1114.
 
5) Yanai K, Tashiro M. The physiological and pathophysiological roles of neuronal histamine : An insight from human PET studies. Pharmacol Ther 2007 ; 113 : 1-15.
PubMed
P.233 掲載の参考文献
1) Sakurai T, et al. Orexins and orexin receptors : A family of hypothalamic neuropeptides and G proteincoupled receptors that regulate feeding behavior. Cell 1998 ; 92 (4) : 573-585.
 
2) de Lecea L, et al. The hypocretins : Hypothalamusspecific peptides with neuroexcitatory activity. Proc Natl Acad Sci U S A 1998 ; 95 (1) : 322-327.
PubMed
3) Sakurai T. The neural circuit of orexin (hypocretin) : Maintaining sleep and wakefulness. Nat Rev Neurosci 2007 ; 8 (3) : 171-181.
PubMed
4) Sakurai T, et al. Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice. Neuron 2005 ; 46 (2) : 297-308.
PubMed
5) Yamanaka A, et al. Hypothalamic orexin neurons regulate arousal according to energy balance in mice. Neuron 2003 ; 38 (5) : 701-713.
PubMed
P.235 掲載の参考文献
1) Anggadiredja K, et al. Endocannabinoid system modulates relapse to methamphetamine seeking : Possible mediation by the arachidonic acid cascade. Neuropsychopharmacology 2004 ; 29 : 1470-1478.
PubMed
Yamamoto T, Takada K. Role of cannabinoid receptor in the brain as its relates to drug reward. Jpn J Pharmacol 2000 ; 84 : 229-236.
PubMed
Yamamoto T, Anggadiredja K, Hiranita T. New perspectives in the studies on endocannabinoid and cannabis : A role for the endocannabinoid-arachidonic acid pathway in drug reward and long-lasting relapse to drug taking. J Pharmacol Sci 2004 ; 96 (4) : 382-388.
PubMed
山本経之. カンナビノイド受容体-中枢神経系における役割. 日本薬理学雑誌 2007 ; 130 : 135-140.
Medical*Online
Solinas M, Yasar S, Goldberg SR. Endocannabinoid system involvement in brain reward processes related to drug abuse. Pharmacol Res 2007 ; 56 (5) : 393-405.
PubMed
P.238 掲載の参考文献
1) Smith JW, Stolerman IP. Recognising nicotine : The neurobiological basis of nicotine discrimination. In : Henningfield JE, et al (eds). Nicotine Psychopharmacology, Handbook of Experimental Pharmacology 192. Berlin : Springer-Verlag ; 2009. pp295-333.
 
2) Galanter JM, Lowenstein DH. 神経系の生理学と薬理学の原理-血液脳関門. 清野裕 (日本語版監修). ハーバード大学テキスト 病態生理に基づく臨床薬理学. 東京 : メディカル・サイエンス・インターナショナル ; 2006. pp87-88.
 
3) Sharma A, Brody AL. In vivo brain imaging of human exposure to nicotine and tobacco : The neurobiological basis of nicotine discrimination. In : Henningfield JE, et al (eds). Nicotine Psychopharmacology, Handbook of Experimental Pharmacology 192. Berlin : Springer-Verlag ; 2009. pp295-333.
 
4) Kubota T, et al. CYP2A6 polymorphisms are associated with nicotine dependence and influence withdrawal symptoms in smoking cessation. Pharmacogenomics J 2006 ; 6 : 115-119.
PubMed
5) Greenbaum L, Lerer B. Differential contribution of genetic variation in multiple brain nicotinic cholinergic receptors to nicotine dependence : Recent progress and emerging open questions. Mol Psychiatry 2009 ; 14 : 912-945.
PubMed
P.240 掲載の参考文献
1) Diamond M. Sex reassignment at birth : Long term review and clinical implications. Arch Pediatr Adolesc Med 1997 ; 151 : 298-304.
PubMed
2) Imperato-Mcginley J. Androgens and the evolution of male gender identity among male pseudohermaphrodites with 5 alpha-reductase deficiency. N Engl J Med 1979 ; 300 : 1233-1237.
PubMed
3) Mendez JP. Male pseudohermaphrodites due to primary 5 alpha-reductase deficiency : Variation in gender identity reversal in seven Mexican patients from five different pedigrees. J Endocrinol Invest 1995 ; 18 : 205-213.
PubMed
4) Zhou JN, et al. A sex difference in the human brain and its relation to transsexuality. Nature 1995 ; 378 : 68-71.
PubMed
5) Hare L. Androgen receptor repeat length polymorphism associated with male-to-female transsexualism. Biol Psychiatry 2009 ; 65 (1) : 93-96.
PubMed
6) Hembree WC, et al. Endocrine treatment of transsexual persons : An Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2009 ; 94 (9) : 3132-3154.
PubMed
P.243 掲載の参考文献
1) Seeman MV. Psychopathology in women and men : Focus on female hormones. Am J Psychiatry 1997 ; 154 (12) : 1641-1647.
PubMed
2) Hiroi R, McDevitt RA, Neumaier JF. Estrogen selectively increases tryptophan hydroxylase-2 mRNA expression in distinct subregions of rat midbrain raphe nucleus : Association between gene expression and anxiety behavior in the open field. Biol Psychiatry 2006 ; 60 (3) : 288-295.
PubMed
3) Kuiper GG, et al. Cloning of a novel receptor expressed in rat prostate and ovary. Proc Natl Acad Sci U S A 1996 ; 93 (12) : 5925-5930.
PubMed
4) Mitra SW, et al. Immunolocalization of estrogen receptor beta in the mouse brain : Comparison with estrogen receptor alpha. Endocrinology 2003 ; 144 (5) : 2055-2067.
PubMed
5) Jensen EV, Jacobson HI. Fate of steroid estrogens in target tissues. In : Pincus G, et al (eds). Biological Activities of Steroids in Relation to Cancer. New York : Academic Press ; 1960. pp161-174.
 
6) Sugiyama N, et al. Spatiotemporal dynamics of the expression of estrogen receptors in the postnatal mouse brain. Mol Psychiatry 2009 ; 14 (2) : 223-232, 117.
PubMed
7) Sugiyama N, et al. Abnormally large, heavy brain with a decreased number of apoptotic cells in CYP7B1 knockout mice. Mol Psychiatry 2009 ; 14 (2) : 117.
 
Osterlund MK, Witt MR, Gustafsson JA. Estrogen action in mood and neurodegenerative disorders : Estrogenic compounds with selective properties-the next generation of therapeutics. Endocrine 2005 ; 28 (3) : 235-242.
PubMed
Osterlund MK. Underlying mechanisms mediating the antidepressant effects of estrogens. Biochim Biophys Acta 2009. Nov.10. [Epub ahead of print]
 

IV 神経生理学と脳画像研究

P.249 掲載の参考文献
1) 松岡洋夫. てんかんの精神症状 : 病態と鑑別診断. 精神経誌 2005 ; 107 : 264-269.
 
2) 松岡洋夫. てんかん臨床から発作発現のメカニズムに迫る : 神経心理学的アプローチ. 佐藤光源ほか (編). てんかん : けいれん準備性と発作発現の神経機構. 東京 : 学術出版センター ; 1995. pp129-141.
 
3) Matsuoka H, et al. Impairment of parietal cortical functions associated with episodic prolonged spikewave discharges. Epilepsia 1986 ; 27 : 432-436.
 
4) 刑部和仁ほか. 反響言語, 保続を主徴とした非けいれん性てんかん重延状態の一例 : 全般性棘・徐波複合の連続に伴う精神症状を中心に. 精神医学 1992 ; 34 : 995-1002.
 
5) 藤山航ほか. clobazam投与によって強制正常化を呈した前頭葉てんかんの一例. 脳と精神の医学 2002 ; 13 : 427-431.
 
6) 松岡洋夫. 認知誘発発作. 鈴木二郎ほか (編). 臨床精神医学講座 第24巻 てんかん. 東京 : 中山書店 ; 1998. pp375-381.
 
7) Matsuoka H. Behavioral precipitants of seizures. In : Schachter SC, et al (eds). Behavioral Aspects of Epilepsy : Principles & Practice. New York : Demos ; 2008. pp131-137.
 
8) Matsuoka H, et al. Neuropsychological EEG activation in patients with epilepsy. Brain 2000 ; 123 : 318-330.
PubMed
9) Matsuoka H. Neuropsychology of epilepsy. Epilepsia 2001 ; 42 (supple 6) : 42-46.
 
P.252 掲載の参考文献
1) 前川敏彦, 飛松省三. 早分かり誘発電位 (4) 事象関連電位とミスマッチ陰性電位. 臨床脳波 2005 ; 47 (12) : 775-787.
 
2) Onitsuka T, et al. Differential characteristics of the middle latency auditory evoked responses to interstimulus intervals. Clin Neurophysiol 2003 ; 114 (8) : 1513-1520.
PubMed
3) 平野羊嗣, 鬼塚俊明, 神庭重信. 音に対する感覚フィルタリング機構. 臨床脳波 2007 ; 49 (1) : 56-64.
Medical*Online
4) 川久保友紀, 笠井清登. 自閉症の神経精神生理学的研究. 臨床精神医学 2008 ; 37 (10) : 1315-1322.
Medical*Online
5) Onitsuka T, et al. Functional and structural deficits in brain regions subserving face perception in schizophrenia. Am J Psychiatry 2006 ; 163 (3) : 455-462.
PubMed
鶴紀子 (編著). 臨床脳波と脳波解析. 東京 : 新興医学出版社 ; 2000.
 
P.256 掲載の参考文献
1) 平野羊嗣, 鬼塚俊明, 神庭重信. 音に対する感覚フィルタリング機構. 臨床脳波 2007 ; 49 (1) : 56-64.
Medical*Online
2) Hirano Y, et al. Auditory gating deficit to human voices in schizophrenia : A MEG study. Schizophr Res 2010 ; 117 (1) : 61-67.
PubMed
3) Kasai K, et al. Neuromagnetic correlates of impaired automatic categorical perception of speech sounds in schizophrenia. Schizophr Res 2003 ; 59 (2-3) : 159-172.
 
4) Teale P, et al. Cortical source estimates of gamma band amplitude and phase are different in schizophrenia. Neuroimage 2008 ; 42 (4) : 1481-1488.
PubMed
5) Hirano S, et al. Abnormal neural oscillatory activity to speech sounds in schizophrenia : A MEG study. J Neurosci 2008 ; 28 (19) : 4897-4903.
 
6) Bassett DS, et al. Cognitive fitness of cost-efficient brain functional networks. Proc Natl Acad Sci U S A 2009 ; 106 (28) : 11747-11752.
PubMed
7) Reite M, et al. MEG auditory evoked fields suggest altered structural/functional asymmetry in primary but not secondary auditory cortex in bipolar disorder. Bipolar Disord 2009 ; 11 (4) : 371-381.
 
Hamalainen M, et al. Magnetoencephalography-theory, instrumentation, and applications to noninvasive studies of the working human brain. Rev Mod Phys 1993 ; 65 (2) : 413-497.
 
Uhlhaas PJ, Mishara AL. Perceptual Anomalies in Schizophrenia. Schizophr Bull 2007 ; 33 (1) : 142-156.
PubMed
Uhlhaas PJ, Singer W. Abnormal neural oscillations and synchrony in schizophrenia. Nat Rev Neurosci 2010 ; 11 (2) : 110-113.
 
Stufflebeam SM, Rosen BR. Mapping cognitive function. Neuroimaging. Clin N Am 2007 ; 17 (4) : 469-484.
PubMed
Reite M, Teale P, Rojas DC. Magnetoencephalography : Applications in psychiatry. Biol Psychiatry 1999 ; 45 (12) : 1553-1563. Review.
PubMed
P.259 掲載の参考文献
1) Geuze E, Vermetten E, Bremner JD. MR-based in vivo hippocampal volumetrics : 2. Findings in neuropsychiatric disorders. Mol Psychiatry 2005 ; 10 (2) : 160-184.
PubMed
2) Davidson LL, Heinrichs RW. Quantification of frontal and temporal lobe brain-imaging findings in schizophrenia : A meta-analysis. Psychiatry Res 2003 ; 122 (2) : 69-87.
PubMed
3) Videbech P, Ravnkilde B. Hippocampal volume and depression : A meta-analysis of MRI studies. Am J Psychiatry 2004 ; 161 (11) : 1957-1966.
PubMed
4) Kitayama N, et al. Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder : A meta-analysis. J Affect Disord 2005 ; 88 (1) : 79-86.
PubMed
5) Honea R, et al. Regional deficits in brain volume in schizophrenia : A meta-analysis of voxel-based morphometry studies. Am J Psychiatry 2005 ; 162 (12) : 2233-2245.
PubMed
6) Kasai K, et al. Progressive decrease of left Heschl gyrus and planum temporale gray matter volume in first-episode schizophrenia : A longitudinal magnetic resonance imaging study. Arch Gen Psychiatry 2003 ; 60 (8) : 766-775.
PubMed
7) Kasai K, et al. Progressive decrease of left superior temporal gyrus gray matter volume in patients with first-episode schizophrenia. Am J Psychiatry 2003 : 160 (1) : 156-164.
PubMed
8) Nakamura M, et al. Neocortical gray matter volume in first-episode schizophrenia and first-episode affective psychosis : A cross-sectional and longitudinal MRI study. Biol Psychiatry 2007 ; 62 (7) : 773-783.
PubMed
9) Takahashi T, et al. Progressive gray matter reduction of the superior temporal gyrus during transition to psychosis. Arch Gen Psychiatry 2009 ; 66 (4) : 366-376.
PubMed
10) Moore GJ, et al. A longitudinal study of the effects of lithium treatment on prefrontal and subgenual prefrontal gray matter volume in treatment-responsive bipolar disorder patients. J Clin Psychiatry 2009 ; 70 (5) : 699-705.
PubMed
11) Lieberman JA, et al. Antipsychotic drug effects on brain morphology in first-episode psychosis. Arch Gen Psychiatry 2005 ; 62 (4) : 361-370.
PubMed
八幡憲明, 根本清貴, 山下典生. 精神医学Update-最新研究動向 精神疾患の脳画像データベース構築へ向けて-研究資産としての脳画像. 医学の歩み 2009 ; 231 (10) : 991-995.
 
平安良雄, 笠井清登 (編著). 精神疾患の脳画像解析・診断学. 東京 : 南山堂 ; 2008.
 
P.262 掲載の参考文献
1) Ogawa S, Lee TM. Magnetic resonance imaging of blood vessels at high fields : In vivo and in vitro measurements and image simulation. Magn Reson Med 1990 ; 16 (1) : 9-18.
PubMed
2) Logothetis NK. What we can do and what we cannot do with fMRI. Nature 2008 ; 453 (7197) : 869-878.
 
3) Takahashi H, et al. An fMRI study of differential neural response to affective pictures in schizophrenia. Neuroimage 2004 ; 22 (3) : 1247-1254.
PubMed
4) Kasai K, et al. Evidence for functional abnormality in the right auditory cortex during musical hallucinations. Lancet 1999 ; 354 (9191) : 1703-1704.
PubMed
5) Raij TT, et al. Reality of auditory verbal hallucinations. Brain 2009 ; 132 : 2994-3001.
PubMed
6) Minzenberg MJ, et al. Meta-analysis of 41 functional neuroimaging studies of executive function in schizophrenia. Arch Gen Psychiatry 2009 ; 66 (8) : 811-822.
PubMed
7) Terry J, Lopez-Larson M, Frazier JA. Magnetic resonance imaging studies in early onset bipolar disorder : An updated review. Child Adolesc Psychiatr Clin N Am 2009 ; 18 (2) : 421-439, ix-x.
 
8) Duncan J. The current status of neuroimaging for epilepsy. Curr Opin Neurol 2009 ; 22 (2) : 179-184.
PubMed
9) Nakao T, et al. Working memory dysfunction in obsessive-compulsive disorder : A neuropsychological and functional MRI study. J Psychiatr Res 2009 ; 43 (8) : 784-791.
PubMed
P.264 掲載の参考文献
1) 福田正人, 三國雅彦, 心の健康に光トポグラフィー検査を応用する会. 近赤外線スペクトロスコピィNIRSによる統合失調症と感情障害の補助診断. 精神医学 2007 ; 49 : 231-243.
 
P.267 掲載の参考文献
1) Friston K. Statistical parametric mapping. In : Friston KJ, et al (eds). Statistical Parametric Mapping. The Analysis of Functional Brain Images, 1st edition. San Diego : Elsevier and Academic Press ; 2007. pp10-31.
 
2) Matsuda H, et al. Contribution of subtraction ictal SPECT coregistered to MRI to epilepsy surgery : A multicenter study. Ann Nucl Med 2009 ; 23 : 283-291.
PubMed
3) McGuire P, et al. Functional neuroimaging in schizophrenia : Diagnosis and drug discovery. Trends Pharmacol Sci 2008 ; 29 : 91-98.
PubMed
4) van de Ven VG, et al. The spatiotemporal pattern of auditory cortical responses during verbal hallucinations. Neuroimage 2005 ; 27 : 644-655.
PubMed
5) Drevets WC, Price JL, Furey ML. Brain structural and functional abnormalities in mood disorders : Implications for neurocircuitry models of depression. Brain Struct Funct 2008 ; 213 : 93-118.
PubMed
松本良平, 須原哲也. PET によるセロトニントランスポーターのイメージングから見たうつ病の病態と治療. 日本薬理学雑誌 2007 ; 130 : 464-468.
Medical*Online
Allen P, et al. The hallucinating brain : A review of structural and functional neuroimaging studies of hallucinations. Neurosci Biobehav Rev 2008 ; 32 : 175-191.
 
Meyer JH. Applying neuroimaging ligands to study major depressive disorder. Semin Nucl Med 2008 ; 38 : 287-304.
PubMed
P.269 掲載の参考文献
1) Haidt J. The moral emotions. In : Davidson RJ, et al (eds). Handbook of Affective Sciences. Oxford : Oxford University Press ; 2003. pp852-870.
 
2) Takahashi H, et al. Brain activation associated with evaluative processes of guilt and embarrassment : An fMRI study. Neuroimage 2004 ; 23 (3) : 967-974.
PubMed
3) Frith U, Frith CD. Development and neurophysiology of mentalizing. Philos Trans R Soc Lond B Biol Sci 2003 ; 358 (1431) : 459-473.
PubMed
4) Amodio DM, Frith CD. Meeting of minds : The medial frontal cortex and social cognition. Nat Rev Neurosci 2006 ; 7 (4) : 268-277.
PubMed
5) Moll J, et al. The neural basis of human moral cognition. Nat Rev Neurosci 2005 ; 6 (10) : 799-809.
PubMed
6) Takahashi H, et al. Brain activations during judgments of positive self-conscious emotion and positive basic emotion : Pride and joy. Cereb Cortex 2008 ; 18 (4) : 898-903.
PubMed
Davidson RJ, Scherer KR Goldsmith HH. Eds Handbook of Affective Science. New york : Oxford University Press ; 2003.
 
Kalat JW, Shiota MN. Emotion. Belmont : Thomson Wadsworth ; 2007.
 
P.274 掲載の参考文献
1) Collingridge GL. Synaptic plasticity. The role of NMDA receptors in learning and memory. Nature 1987 ; 330 (6149) : 604-605.
 
2) Bliss TV, Lomo T. ong-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. J Physiol 1973 ; 232 (2) : 331-356.
 
3) Mayford M, et al. CaMKII regulates the frequencyresponse function of hippocampal synapses for the production of both LTD and LTP. Cell 1995 ; 81 (6) : 891-904.
PubMed
4) Kohda K, et al. Glucocorticoid receptor activation is involved in producing abnormal phenotypes of singleprolonged stress rats : A putative post-traumatic stress disorder model. Neuroscience 2007 ; 148 (1) : 22-33.
PubMed
5) Yamauchi Y, et al. Vulnerability of synaptic plasticity in the complexin II knockout mouse to maternal deprivation stress. Brain Res 2005 ; 1056 (1) : 59-67.
PubMed
Collingridge GL, Bliss TV. Memories of NMDA receptors and LTP. Trends Neurosci 1995 ; 18 (2) : 54-56.
PubMed
Kamiya A, Kitabatake Y, Sawa A. Neurodevelopmental disturbance in the pathogenesis of major mental disorders. Brain Nerve 2008 ; 60 (4) : 445-452.
PubMed
Nabeshima T, et al. Animal model of schizophrenia : Dysfunction of NMDA receptor-signaling in mice following withdrawal from repeated administration of phencyclidine. Ann N Y Acad Sci 2006 ; 1086 : 160-168.
PubMed

V 神経心理学と認知科学

P.280 掲載の参考文献
1) Tinbergen N. On Aims and Methods in Ethology. Zeitschrift fur Tierpsychologie 1963 ; 20 : 410-433.
 
2) 豊嶋良一, 高畑圭輔. 意識現象の「特異性」の科学, その基礎概念-意識・情報・時空間構造 (パタン) ・ニューロン群同期発火. 分子精神医学 2009 ; 9 (2) : 114-122.
Medical*Online
3) Varela F. Neurophenomenology : A methodological remedy to the hard problem. Journal of Consciousness Studies 1996 ; 3 : 330-350.
 
4) Edelman GM. Wider than the Sky. The Phenomenal Gift of Consciousness. New Haven : Yale University Press ; 2004/冬樹純子 (訳). 豊嶋良一 (監修). 「脳は空より広いか-私という現象を考える. 東京 : 草思社 ; 2006.
 
5) Tononi G. Consciousness as integrated information : A provisional manifesto. Biol Bull 2008 ; 215 (3) : 216-242.
PubMed
6) デイヴィット・ローズ. 苧阪直行 (監訳). 意識の脳内表現-心理学と哲学からのアプローチ. 東京 : 培風館 ; 2008.
 
7) 長谷川寿一, 長谷川眞理子. 進化と人間行動. 東京 : 東京大学出版会 ; 2000.
 
8) Stevens A. Archetype. A Natural History of the Self. London : Routledge ; 1982/相馬寿明 (訳). 自己実現の心理学-元型論入門. 東京 : どうぶつ社 ; 1996.
 
9) 豊嶋良一, 小山 毅. 進化心理学からのインパクト-精神保健・自己実現・幸福感の条件. 精神医学 2009 ; 51 (3) : 265-274.
 
10) Stevens A, Price J. Evolutionary Psychiatry. A New Beginning. London : Routledge ; 1996
 
11) 神庭重信. 生物進化からみたこころとその病理. 臨床精神医学 2001 ; 30 : 17-20.
Medical*Online
P.284 掲載の参考文献
1) Mohr JP, et al. Broca aphasia : Pathologic and clinical. Neurology 1978 ; 28 : 311-324.
PubMed
2) Damasio H, et al. The return of Phineas Gage : Clues about the brain from the skull of a famous patient. Science 1994 ; 264 : 1102-1105.
PubMed
3) 山鳥重. 神経心理学入門. 東京 : 医学書院 ; 1985.
 
4) 村井俊哉. 人格・行動の変化と前頭葉損傷. 加藤忠史 (編), シリーズ脳科学 第6巻, 精神の脳科学. 東京 : 東京大学出版会 ; 2008.
 
5) Adolphs R, et al. Impaired recognition of emotion in facial expressions following bilateral damage to the human amygdala. Nature 1994 ; 372 : 669-672.
 
大東祥孝. 神経心理学の新たな展開 : 精神医学の「脱構築」にむけて. 精神神経学雑誌 2006 ; 108 : 1009-1028.
 
山鳥重. 神経心理学入門. 東京 : 医学書院 ; 1985.
 
村井俊哉. 人格・行動の変化と前頭葉損傷. 加藤忠史 (編), シリーズ脳科学 第6巻, 精神の脳科学. 東京 : 東京大学出版会 ; 2008.
 
P.287 掲載の参考文献
1) Green MF, et al. Approaching a consensus cognitive battery for clinical trials in schizophrenia : The NIMH-MATRICS conference to select cognitive domains and test criteria. Biol Psychiatry 2004 ; 56 (5) : 301-307.
PubMed
2) Baddeley A. Fractionating the central executive. In : Stuss DT, et al (eds). Principle of Frontal Lobe Function. New York : Oxford University Press ; 2002. pp246-260.
 
3) Goldman-Rakic PS. Prefrontal cortical dysfunction of
 
4) Servan-Schreiber D, Cohen JD, Steingard S. Schizophrenic deficits in the processing of context. A test of a theoretical model. Arch Gen Psychiatry 1996 ; 53 (12) : 1105-1112.
PubMed
5) Cohen JD, et al. Context-processing deficits in schizophrenia : Converging evidence from three theoretically motivated cognitive tasks. J Abnorm Psychol 1999 ; 108 (1) : 120-133.
PubMed
6) Barch DM, et al. Selective deficits in prefrontal cortex function in medication-naive patients with schizophrenia. Arch Gen Psychiatry 2001 ; 58 (3) : 280-288.
PubMed
7) 加藤元一郎, 鹿島晴雄. 分裂病とワーキングメモリ障害仮説. 脳の科学 1998 ; 20 : 427-432.
 
鹿島晴雄, 加藤元一郎. 神経心理学-作動記憶の障害について. 松下正明ほか (編). 臨床精神医学講座 2, 精神分裂病 I. 東京 : 中山書店 ; 1999. pp281-p290.
 
P.290 掲載の参考文献
1) Premack D, Woodruff G. Does the chimpanzee have a theory of mind? Behav Brain Sci 1978 ; 1 : 515-526.
 
2) Byrne R. The Thinking Ape : Evolutionary Origins of Intelligences. Oxford : Oxford University Press ; 1995.
 
3) Brothers L. The social brain : A project for integrating primate behavior and neurophysiology in a new domain. Concept Neurosci 1990 ; 1 : 27-51.
 
4) Baron-Cohen S, Leslie A, Frith U. Does the autistic child have a "theory of mind"?. Cognition 1985 ; 21 : 37-46.
PubMed
5) Brune M. Social cognition and psychopathology in an evolutionary perspective. Psychopathology 2001 ; 34 : 85-94.
 
6) Obayashi C, et al. Decreased spatial frequency sensitivities for processing faces in male patients with chronic schizophrenia. Clin Neurophysiol 2009 ; 120 : 1525-1533.
PubMed
7) Inoue Y, Yamada K, Kanba S. Deficit in theory of mind is a risk for relapse of major depression. J Affect Disord 2006 ; 95 : 125-127.
PubMed
Adolphs R. Cognitive neuroscience of human social behaviour. Nat Rev Neurosci 2003 ; 4 : 165-178.
PubMed
Kanba S, Yamada K, Inoue Y. Deficit of theory of mind in depression and its correlation with poor clinical outcomes. In : Paul H (ed). Metacognition and Severe Adult Mental Disorders : From Research to Treatment. Lysaker : Routledge ; 2010.
 
Brune M, Ribbert H, Schiefenhovel W. The Social Brain : Evolution and Pathology. Wiley ; 2003.
 
関一夫, 長谷川寿一. ソーシャルブレインズ-自己と他者を認知する脳. 東京 : 東京大学出版会 ; 2009.
 
P.292 掲載の参考文献
1) Rizzolatti G, et al. Premotor cortex and the recognition of motor actions. Cogn Brain Res 1996 ; 3 : 131-141.
PubMed
2) Premack D, Woodruff G. Does the chimpanzee have a theory of mind? Behav Brain Sci 1978 ; 1 : 515-526.
 
3) 井上由美子, 山田和男, 神庭重信. 「社会脳」と「心の理論」. 分子精神医学 2004 ; 4 : 7-11.
 
4) Singer T, et al. Empathy for pain involves the affective but not sensory components of pain. Science 2004 ; 303 : 1157-1162.
 
Rizzolatti G, Sinigaglia C. ミラーニューロン. 柴田裕之 (訳), 茂木健一郎 (監修). 東京 : 紀伊國屋書店 ; 2009.
 
P.294 掲載の参考文献
1) Capgras J, Reboul-Lachaux J. L'illusion des "sosies" dans un delire systematize. Bull Soc Clin Med Ment 1923 ; 11 : 6-16.
 
2) Christodoulou GN (ed). The Delusional Misidentification Syndromes. Basel : Karger ; 1986.
 
3) Ellis HD, Young AW. Accounting for delusional misidentification. Br J Psychiatry 1990 ; 157 : 239-248.
PubMed
4) Alexander MP, Stuss DT, Benson DF. Capgras syndrome : A reduplicative phenomenon. Neurology 1979 ; 29 : 334-339.
PubMed
5) Margariti M, Kontaxakis V. Approaching delusional misidentification disorders as a disorder of the sense of uniqueness. Psychopathology 2006 ; 39 : 261-268.
PubMed
6) Feinberg TE, Roane DM. Delusional misidentification. Psychiatr Clin North Am 2005 ; 28 : 665-683.
PubMed
7) Devinsky O. Delusional misidentifications and duplications : Right brain lesions, left brain delusions. Neurology 2009 ; 72 : 80-87.
PubMed
P.297 掲載の参考文献
1) Tobena A, Lethal altruists : Itineraries along the dark outskirts of moralistic prosociality. Ann N Y Acad Sci 2009 ; 1167 : 5-15.
PubMed
2) Baumgartner T, et al. Oxytocin shapes the neural circuitry of trust and trust adaptation in humans. Neuron 2008 ; 58 : 639-650.
PubMed
3) Crockett MJ, et al. Serotonin modulates behavioral reactions to unfairness. Science 2008 ; 320 : 1739.
PubMed
4) Knoch D, et al. Diminishing reciprocal fairness by disrupting the right prefrontal cortex. Science 2006 ; 314 : 829-832.
PubMed
5) Sanfey AG, et al. The neural basis of economic decision-making in the Ultimatum Game. Science 2003 ; 300 : 1755-1758.
PubMed
6) de Quervain DJ, et al. The neural basis of altruistic punishment. Science 2004 ; 305 : 1254-1258.
PubMed
7) Yamagishi T, et al. The private rejection of unfair offers and emotional commitment. Proc Natl Acad Sci U S A 2009 ; 106 : 11520-11523.
PubMed
村井俊哉. 社会におけるヒトの行動パターンを規定するもの. 臨床精神医学 2009 ; 38 : 69-76.
Medical*Online
Montague PR. Neuroeconomics : A view from neuroscience. Funct Neurol 2007 ; 22 : 219-234.
PubMed
Frith CD, Singer T. The role of social cognition in decision making. Philos Trans R Soc Lond B Biol Sci 2008 ; 363 : 3875-3886.
PubMed
Loewenstein G, Rick S, Cohen JD. Neuroeconomics. Annu Rev Psychol 2008 ; 59 : 647-672.
PubMed
Fehr E, Camerer CF. Social neuroeconomics : The neural circuitry of social preferences. Trends Cogn Sci 2007 ; 11 : 419-427.
PubMed
Tobena A, Lethal altruists : Itineraries along the dark outskirts of moralistic prosociality. Ann N Y Acad Sci 2009 ; 1167 : 5-15.
PubMed
P.302 掲載の参考文献
1) Crick F, Koch C. Towards a neurobiological theory of consciousness. Seminars in the Neurosciences 1990 ; 2 : 263-275.
 
2) Chalmers DJ. On the Search for the Neural Correlates of Consciousness. Toward a Science of Consciousness II. Cambridge : MIT Press ; 1998.
 
3) Varela F. Neurophenomenology : A methodological remedy to the hard problem. Journal of Consciousness Studies 1996 ; 3 : 330-350.
 
4) Pascual-Leone A, Walsh V. Fast backprojections from the motion to the primary visual area necessary for visual awareness. Science 2001 ; 292 : 510-512.
 
5) Gray CM, Singer W. Stimulus-specific neuronal oscillations in orientation columns of cat visual cortex. Proc Natl Acad Sci U S A 1989 ; 86 : 1698-1702.
PubMed
6) Tononi G. An information integration theory of consciousness. BMC Neurosci 2006 ; 5 : 1-22.
 
7) Edelman GM. Wider than the Sky. The Phenomenal Gift of Consciousness. New Haven : Yale University Press ; 2004/冬樹純子 (訳). 豊嶋良一 (監修). 脳は空より広いか-私という現象を考える. 東京 : 草思社 ; 2006.
 
8) Achard S, et al. A resilient, low-frequency, smallworld human brain functional network with highly connected association cortical hubs. J Neurosci 2006 ; 26 : 63-72.
PubMed
9) Dehaene S, et al. Conscious, preconscious, and subliminal processing : A testable taxonomy. Trends Cogn Sci 2006 ; 10 : 204-211.
PubMed
10) Spencer KM, Nestor PG, McCarley RW. Abnormal neural synchrony in schizophrenia. J Neurosci 2003 ; 23 : 7407-7411.
PubMed
Tononi G, Koch C. The neural correlates of consciousness : An update. Ann N Y Acad Sci 2008 ; 1124 : 239-261.
PubMed
Koch C. The Quest for Consciousness. A Neurobiological Approach. Denver : Roberts ; 2004.
 
豊嶋良一. 「精神の科学」が目指すもの-主観的体験という現象解明のヒントを求めて. 脳と精神の医学 2002 ; 13 : 367-375.
 
Varela F, et al. The brainweb : Phase synchronization and large-scale integration. Nat Rev Neurosci 2001 ; 2 : 229-239.
PubMed
高畑圭輔, 豊嶋良一. 意識 (主観的体験) の神経科学的モデルと統合失調症. 分子精神医学 2009 ; 9 (2) : 131-141.
Medical*Online
P.304 掲載の参考文献
1) Marr D. Vision : A Computational Investigation into the Human Representation and Processing of Visual Information. New York, Oxford : WH Freeman ; 1982.
 
2) Dayan P, Abbott LF. Theoretical Neuroscience : Computational and Mathematical Modeling of Neural Systems, 1st edition. Cambridge : The MIT Press ; 2005.
 
3) Arbib MA. The Handbook of Brain Theory and Neural Networks, 2nd edition. Cambridge : The MIT Press ; 2003.
 
4) Sutton RS, Barto AG. Reinforcement Learning : An Introduction. Cambridge : The MIT Press ; 1998.
 
5) Houk JC, Davis JL, Beiser DG (eds). Models of Information Processing in the Basal Ganglia, 1st edition. Cambridge : The MIT Press ; 1994.
 
6) Glimcher PW, et al (eds). Neuroeconomics : Decision Making and the Brain, 1st edition. Sandiego : Academic Press ; 2009.
 
甘利俊一. 神経回路網の数理-脳の情報処理方式. 東京 : 産業図書 ; 1978.
 
川人光男. 脳の計算理論. 東京 : 産業図書 ; 1996.
 
深井朋樹 (編). 脳の計算論. 東京 : 東京大学出版会 ; 2009.
 
理化学研究所 脳科学総合研究センター (編). 脳研究の最前線 上・下 (ブルーバックス B1570・1571). 東京 : 講談社 ; 2007.
 

書評

最近チェックした商品履歴

Loading...