極論で語る消化器内科

出版社： 丸善出版
著者：
発行日： 2018-10-10
分野： 臨床医学：内科  >  消化器一般
ISBN： 9784621303290
シリーズ： 極論で語るシリーズ
電子書籍版： 2019-10-10 （電子書籍版）
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消化器内科といえば 研修医の鉄板中の，鉄板…，コモン疾患ばかりですよね．でもすぐ内視鏡を依頼したり，あるいは胃薬でお茶を濁したりしていませんか？ できる内科医になるには，内科系疾患で最も頻度の高い消化管や肝胆膵疾患を診なければなりません．便秘，下痢にはじまり，消化管出血，胃食道逆流症，機能性ディスペプシア…の対処法や各種検査の捉え方も学べます．

目次

  • １章　消化管出血［gastrointestinal bleeding］
    極論1　血行動態を何よりも（内視鏡よりも）優先させる
    極論2　数分で把握する病歴と身体所見
    極論3　黒色便と鮮血便の本当の意味は…？
    極論4　リスク評価は経験のない若手の味方
    極論5　過剰な輸血はしない
    コラム1 小腸出血

    2章　胃食道逆流症［GERD］
    極論1　警告徴候がなければPPI，診断的治療でもPPI
    極論2　PPI投与，じつは「食後」よりも「食前」
    極論3　無敵のPPIにも「弱点」はある
    極論4　生活指導でPPIをサポートする
    極論5　GERDは胸焼けだけではない
    コラム１　バレット食道

    3章　消化性潰瘍［peptic ulcer］
    極論1　潰瘍の原因はストレス・コーヒーよりも「ピロリ・NSAIDs」
    極論2　酸分泌の抑制，これ一本で勝負！
    極論3　みつかったらすぐに「除菌」
    極論4　悪性病変の除外を忘れない
    コラム1 HP 感染胃の内視鏡所見

    4章　胆石関連疾患［gallstone disease］
    極論1　 癪は胆石か…？　
    極論2　無症候であれば，経過観察もしない
    極論3　結石がなくても胆嚢炎は起きる
    極論4　急性胆管炎はとにかく狭窄の解除

    5章：肝臓系検査［liver test］
    極論1　「肝機能検査」という用語を使わない
    極論2　肝臓系検査異常は3パターンに落とし込む
    極論3　肝臓の合成能はアルブミン，プロトロンビン時間（PT）

    6章　下痢［diarrhea］
    極論1　発症4週間以内か？ 以上か？ それが問題だ
    極論2　便培養よりむしろCDトキシン
    極論3　医原性の下痢は意外と多い
    極論4　慢性下痢ではまず，IBSを除外する
    極論5　便のことを聞く！
    コラム1 自宅での経口補水液のつくり方
    コラム2　便の浸透圧較差

    7章　便秘［constipation］
    極論1　便秘の陰に「病」あり
    極論2　「患者の悩みは何なのか…？」を知る　
    極論3　治療戦略は3つに分ける（特発性便秘）：「NTC」「STC」「機能性便排出障害」
    極論4　刺激性下剤の乱用はよくみかける
    コラム1　日本でもようやく「慢性便秘症診療ガイドライン」

    8章　嚥下障害［dysphagia］
    極論1　まず症状発現のタイミングで分ける．「すぐか？」「 数秒後か？」
    極論2　食道性嚥下障害は「内視鏡」が必須
    極論3　口腔咽頭性嚥下障害なら「嚥下造影検査」「耳鼻科評価」
    極論4　最後は「食道内圧測定」を行う
    コラム1 好酸球性食道炎（eosinophilic esophagitis；EoE）

    9章　機能性ディスペプシア［FD］
    極論1　機能性ディスペプシアでは内科医の素養が試される
    極論2　 FDの分類は食事で
    極論3　まず「除菌」
    極論4　治療の主体は「酸分泌抑制」と「消化管運動機能改善薬」

    10章　過敏性腸症候群［IBS］
    極論1　警告徴候のない慢性的な腹痛がIBS
    極論2　 IBSは4タイプに分類する
    極論3　治療戦略は「便秘型」「下痢型」「混合型」で分ける
    極論4　低FODMAP食も1つの手
    コラム1 腸管ガス（おなら）の原因となる食品を控える

    11章　感染性腸炎［infectious enterocolitis］
    極論1　まず「小腸型か」「大腸型か」を判断する
    極論2　その検査は必要か…？
    極論3　抗菌薬は不要
    極論4　2週間以上下痢が続いたら「頭を切り替える」
    コラム1 腸の問題だけで終わらないこともある

    12章：極論・消化器癌ポプリ［potpourri：ごった煮］
    極論1　腫瘍マーカーは健常人では役立たず
    極論2　便潜血検査を行う前に「陽性ならどうするか…？」を考える
    極論3　フラッシャーでは食道扁平上皮癌のリスクが約３倍
    極論4　分枝膵管型IPMNと最近発症したDMは,通常型膵癌の合併に気をつける

この書籍の参考文献

参考文献のリンクは、リンク先の都合等により正しく表示されない場合がありますので、あらかじめご了承下さい。

本参考文献は電子書籍掲載内容を元にしております。

1章 消化管出血 [ gastrointestinal bleeding ]

P.13 掲載の参考文献
1) Prasad Kerlin M, Tokar JL : Acute gastrointestinal bleeding. Ann Intern Med. 2013 Aug 6 ; 159 (3) : ICT2-1.
 
2) Steven McGee : Evidence-Based Physical Diagnosis.4th ed. Elsevier, Chapter 17 Blood Pressure, 2018 (電子版).
 
3) Laine L, Anthony S. F : Gastrointestinal bleeding. Harrison's Gastroenterology and Hepatology. 2nd ed (電子版).
 
4) Laine L, Shah A : Randomized trial of urgent vs. elective colonoscopy in patients hospitalized with lower GI bleeding. Am J Gastroenterol. 2010 Dec ; 105 (12) : 2636-41.
PubMed
5) Srygley FD, Gerardo CJ, et al : Does this patient have a severe upper gastrointestinal bleed?. JAMA. 2012 Mar 14 ; 307 (10) : 1072-9.
PubMed
6) Rockall TA, Logan RF, et al : Risk assessment after acute upper gastrointestinal haemorrhage. Gut. 1996 Mar ; 38 (3) : 316-21.
PubMed
7) Blatchford O, Murray WR, et al : A risk score to predict need for treatment for upper-gastrointestinal haemorrhage. Lancet. 2000 Oct 14 ; 356 (9238) : 1318-21.
 
8) Saltzman JR, Tabak YP, et al : A simple risk score accurately predicts in-hospital mortality, length of stay, and cost in acute upper GI bleeding. Gastrointest Endosc. 2011 Dec ; 74 (6) : 1215-24.
 
9) Strate LL, Gralnek IM : ACG Clinical Guideline : Management of Patients With Acute Lower Gastrointestinal Bleeding. Am J Gastroenterol. 2016 May ; 111 (5) : 755.
PubMed
10) Green BT, Rocky DC, et al : Urgent colonoscopy for evaluation and management of acute lower gastrointestinal hemorrhage : a randomized controlled trial. Am J Gastroenterol. 2005 Nov ; 100 (11) : 2395-402.
 
11) Villanueva C, Colombo A, et al : Transfusion strategies for acute upper gastrointestinal bleeding. N Engl J Med 2013 ; 368 : 11-21.
 

2章 胃食道逆流症 [ GERD ]

P.25 掲載の参考文献
1) Haag S, Holtmann G : Onset of relief of symptoms of gastroesophageal reflux disease : post hoc analysis of two previously published studies comparing pantoprazole 20mg once daily with nizatidine or ranitidine150mg twice daily. Clin Ther. 2010 Apr ; 32 (4) : 678-90.
PubMed
2) Chiba N, De Gara CJ, et al : Speed of healing and symptom relief in grade II to IV gastroesophageal reflux disease : a meta-analysis. Gastroenterology. 1997 Jun ; 112 (6) : 1798-810.
PubMed
3) Sigterman KE, van Pinxteren B, et al : Short-term treatment with proton pump inhibitors, H2-receptor antagonists and prokinetics for gastro-esophageal reflux diseaselike symptoms and endoscopy negative reflux disease. Cochrane Database Syst Rev. 2013 May 31 ; (5).
 
4) Katz PO, Gerson LB, et al : Guidelines for the Diagnosis and Management of Gastroesophageal Reflux Disease. Am J Gastroenterol. 2013 Mar ; 108 (3) : 308-28.
PubMed
5) Leonard J, Marshall JK, et al : Systematic review of the risk of enteric infection in patients taking acid suppression. Am J Gastroenterol. 2007 Sep ; 102 (9) : 2047-56.
PubMed
6) Kwok CS, Arthur AK, et al : Risk of Clostridium difficile infection with acid suppressing drugs and antibiotics : meta-analysis. Am J Gastroenterol. 2012 Jul ; 107 (7) : 1011-9.
PubMed
7) Janarthanan S, Ditah I, et al : Clostridium difficile-associated diarrhea and proton pump inhibitor therapy : a meta-analysis. Am J Gastroenterol. 2012 Jul ; 107 (7) : 1001-10.
PubMed
8) Sarkar M, Hennessy S, et al : Proton-pump inhibitor use and the risk for community-acquired pneumonia. Ann Intern Med. 2008 Sep 16 ; 149 (6) : 391-8.
 
9) Yu EW, Bauer SR, et al : Proton pump inhibitors and risk of fractures : a meta-analysis of 11 international studies. Am J Med. 2011 Jun ; 124 (6) : 519-26.
PubMed
10) Ra A, Tobe SW : Acute interstitial nephritits due to pantoprazole. Ann Pharmacother. 2004 Jan ; 38 (1) : 41-5..
 
11) Geevasinga N, Coleman PL, et al : Proton pump inhibitors and acute interstitial nephritis. Clin Gastroenterol Hepatol. 2006 May ; 4 (5) : 597-604.
PubMed
12) Lazarus B, Chen Y, et al : Proton pump inhibitor use and the risk of chronic kidney disease. JAMA Intern Med. 2016 Feb ; 176 (2) : 238-46.
PubMed
13) Keszthelyi D, Jansen SV, et al : Proton pump inhibitor use is associated with an increased risk for microscopic colitis : a case-control study. Aliment Pharmacol Ther. 2010 Nov ; 32 (9) : 1124-8.
PubMed
14) Tsai C-F, Chen M-H, et al : Proton pump inhibitors increase risk for hepatic encephalopathy in patients with cirrhosis in a population study. Gastroenterology. 2017 Jan ; 152 (1) : 134-41.
 
15) Marlicz W, Loniewski I, et al : Nonsteroidal anti-inflammatory drugs, proton pump inhibitors and gastrointestinal injury : contrasting interactions in the stomach and small intestine. Mayo Clin Proc. 2014 Dec ; 89 (12) : 1699-709.
PubMed
16) Xie Y, Bowe B, et al : Risk of death among users of Proton Pump Inhibitors : a longitudinal observational cohort study of United States veterans. BMJ Open. 2017 Jul 4 ; 7 (6) : e015735.
 
17) Farrell B, Pottie K, et al. Deprescribing proton pump inhibitors. Evidence-based clinical practice guideline. Can Fam Physician. 2017 May ; 63 (5) : 354-64.
PubMed
18) 日本消化器病学会 胃食道逆流症 (GERD) 診療ガイドライン 2015 (改訂第2版) pp74-8.
 
19) Johnson LF, DeMeester TR : Evaluation of elevation of the head of the bed, bethanecol, and antacid form tablets on gastroesophageal reflux. Dig Dis Sci. 1981 Aug ; 26 (8) : 673-80.
PubMed
20) Stanciu C, Bennett JR : Effects of posture on gastro-oesophageal reflux. Digestion. 1977 Feb ; 15 (2) : 104-9.
PubMed
21) Kaltenbach T, Crockett S, et al : Are lifestyle measures effective in patients with gastroesophageal reflux disease? An evidence-based approach. Arch Intern Med. 2006 May 8 ; 166 (9) : 965-71.
 
22) Pehl C, Wendl B, et al : Low-proof alcoholic beverages and gastroesophageal reflux. Dig Dis Sci. 1993 Jan ; 38 (1) : 93-6.
PubMed
23) Murphy DW, Castell DO : Chocolate and heartburn : evidence of increased esophageal acid exposure after chocolate ingestion. Am J Gastroenterol. 1988 Jun ; 83 (6) : 633-6.
PubMed
24) Becker DJ, Sinclair J, et al : A comparison of high and low fat meals on postprandial esophageal acid exposure. Am J Gastroenterol. 1989 Jul ; 84 (7) : 782-6.
 
25) Shaheen NJ, Falk GW, et al : ACG clinical guideline : Diagnosis and management of Barrett's esophagus. Am J Gastroenterol. 2016 Jan ; 111 (1) : 30-50.
PubMed
26) American Gastroenterological Association, Spechler SJ, et al : American Gastroenterological Association medical position statement on the management of Barrett's esophagus. Gastroenterology. 2011 Mar ; 140 (3) : 1084-91.
PubMed

3章 消化性潰瘍 [ peptic ulcer ]

P.41 掲載の参考文献
1) Chey WD, Leontiadis GI, et al : ACG Clinical Guideline : Treatment of Helicobacter pylori Infection. Am J Gastroenterol. 2017 Feb ; 112 (2) : 212-39.
PubMed
2) McColl KE : Helicobacter pylori Infection. N Engl J Med 2010 ; 362 : 1597-604.
PubMed
3) ヘリコバクター・ピロリ感染胃炎の診断と治療. 日本ヘリコバクター学会誌. 2013, supplement.
 
4) World Gastroenterology Organisation Global Guidelines : Helicobacter pylori in developing countries (http://www.worldgastroenterology.org/guidelines/globalguidelines/helicobacter-pylori-in-developing-countries/helicobacter-pylori-indeveloping-countries-english).
 
5) Gisbert JP, Abraira V : Accuracy of Helicobacter pylori Diagnostic Tests in Patients with Bleeding Peptic Ulcer : A Systematic Review and Meta-analysis. Am J Gastroenterol. 2006 Apr ; 101 (4) : 848-63.
PubMed
6) Piper JM, Ray WA, et al : Cor ticosteroid use and peptic ulcer disease : Role of nonsteroidal anti-inflammatory drugs. Ann Intern Med. 1991 May 1 ; 114 (9) : 735-40.
 
7) Di Mario F, Battaglia G, et al : Short-term treatment of gastric ulcer : a meta-analytical evaluation of blind trials. Dig Dis Sci. 1996 Jun ; 41 (6) : 1108-31.
PubMed
8) Eriksson S, Langstrom G, et al : Omeprazole and H2-receptor antagonists in the acute treatment of duodenal ulcer, gastric ulcer and reflux oesophagitis : a meta-analysis. Eur J Gastroenterol Hepatol. 1995 May ; 7 (5) : 467-75.
PubMed
9) Salas M, Ward A, et al : Are proton pump inhibitors the first choice for acute treatment of gastric ulcers? a meta analysis of randomized clinical trials. BMC Gastroenterol. 2002 Jul 15 ; 2 : 17.
 
10) Tunis SR, Sheinhait LA, et al : Lansoprazole compared with histamine2-receptor antagonists in healing gastric ulcers : a meta-analysis. Clin Ther. 1997 Jul-Aug ; 19 (4) : 743-57.
 
11) 宮原透, 勝健一, 他 : 消化性潰瘍に対するLansoprazole単独投与と粘膜防御因子増強併用投与の比較検討. 薬理と治療, 1997 ; 25 : 2557-68.
 
12) 日本消化器病学会 (編) : 消化性潰瘍診療ガイドライン 2015 (改訂第2版). 2015, 南江堂.
 
13) Liu CP, Chen WC, et al : Esomeprazole alone compared with esomeprazole plus aspirin for the treatment of aspirin-related peptic ulcers. Am J Gastroenterol. 2012 Jul ; 107 (7) : 1022-9.
PubMed
14) Hooper L, Brown TJ, et al : The effectiveness of five strategies for the prevention of gastrointestinal toxicity induced by non-steroidal anti-inflammatory drugs : systematic review. BMJ. 2004 Oct 23 ; 329 (7472) : 948.
 
15) Cook DJ, Fuller HD, et al : Risk factors for gastrointestinal bleeding in critically ill patients. Canadian Critical Care Trials Group. N Engl J Med. 1994 Feb 10 ; 330 (6) : 377-81.
 
16) Moss SF, Harris AD : Chapter 2. Acid Diseases of the Stomach. In Digestive Diseases Self-Education Program. Sweetser S. Ed. AGA Institute Education. 2016.
 
17) Janssen MJ, Laheij RJ, et al : Meta-analysis : the influence of pre-treatment with a proton pump inhibitor on Helicobacter pylori eradication. Aliment Pharmacol Ther. 2005 Feb 15 ; 21 (4) : 341-5.
 
18) Bianchi PG, Parente F, et al : Role of Helicobacter pylori in ulcer healing and recurrence of gastric and duodenal ulcers in long term NSAID users : response to omeprazole dual therapy. Gut. 1996 Jul ; 39 (1) : 22-6.
 
19) Chan FK, Sung JJ, et al : Does eradication of Helicobacter pylori impair healing of nonsteroidal anti-inflammatory drug associated bleeding peptic ulcers? A prospective randomized study. Aliment Pharmacol Ther. 1998 Dec ; 12 (12) : 1201-5.
PubMed
20) Hawkey CJ, Tulassay Z, et al : Randomized controlled trial of Helicobacter pylori eradication in patients on non-steroidal anti-inflammatory drugs : HELP NSAIDs study. Helicobacter Eradication for Lesion Prevention. Lancet. 1998 Sep 26 ; 352 (9133) : 1016-21.
 
21) Del Valle J : Chapter 14 Peptic Ulcer Disease and Related Disorders. In Harrison's Gastroenterology and Hepatology. 2nd Ed. (電子版) Longo DL, Fauci AS. Ed. 2013, McGraw-Hill Education.
 

4章 胆石関連疾患 [ gallstone disease ]

P.54 掲載の参考文献
1) Silen W : Chapter 13, The colics. In Cope's Early Diagnosis of the Acute Abdomen. 22nd Ed. Oxford University Press. 2010.
 
2) Henderson SO, Swadron S, et al : Comparison of intravenous ketorolac and meperidine in the treatment of biliary colic. J Emerg Med. 2002 Oct ; 23 (3) : 237-41.
 
3) Kumar A, Deed JS, et al : Comparison of the effect of diclofenac with hyoscine-Nbutylbromide in the symptomatic treatment of acute biliary colic. ANZ J Surg. 2004 Jul ; 74 (7) : 573-6.
 
4) Gracie WA, Ransohoff DF : The natural histor y of silent gallstones : the innocent gallstone is not a myth. N Engl J Med. 1982 Sep 23 ; 307 (13) : 798-800.
 
5) Del Favero G, Caroli A, et al : Natural history of gallstones in non-insulin-dependent diabetes mellitus. A prospective 5-year follow-up. Dig Dis Sci. 1994 Aug ; 39 (8) : 1704-7.
PubMed
6) Thistle JL, Cleary PA, et al : The natural histor y of cholelithiasis : the National Cooperative Gallstone Study. Ann Intern Med. 1984 Aug ; 101 (2) : 171-5.
 
7) Ransohoff DF, Gracie WA : Treatment of gallstones. Ann Intern Med. 1993 Oct 1 ; 119 (7 Pt 1) : 606-19.
 
8) 急性胆管炎・胆嚢炎診療ガイドライン改訂出版委員会 (編) : 急性胆管炎・胆嚢炎診療ガイドライン 2013. 医学図書出版. 2013.
 

5章 肝臓系検査 [ liver test ]

P.67 掲載の参考文献
1) 独立行政法人 医薬品医療機器総合機構 : 医薬品関連情報 重篤副作用疾患別対応マニュアル (医療者向け) 薬物性肝障害 平成20年4月 厚生労働省 (http://www.info.pmda.go.jp/juutoku/juutoku_index.html).
 

6章 下痢 [ diarrhea ]

P.80 掲載の参考文献
1) Allen SJ, Martinez EG, et al : Probiotics for treating acute infectious diarrhea. Cochrane Database Syst Rev. 2010 Nov 10 ; (11).
 
2) Rehyadration Project (http://rehydrate.org/solutions/homemade.htm#recipe) (Accessed on Aug 11, 2017).
 
3) Bauer TM, Lalvani A, et al : Derivation and validation of guidelines for stool cultures for enteropathogenic bacteria other than Clostridium difficile in hospitalized adults. JAMA. 2001 Jan 17 ; 285 (3) : 313-9.
 
4) Planche T, Aghaizu A, et al : Diagnosis of Clostridium difficile infection by toxin detection kits : a systematic review. Lancet Infect Dis. 2008 Dec ; 8 (12) : 777-84.
 
5) JAID/JSC感染症治療ガイド・ガイドライン作成委員会 : JAID/JSC感染症治療ガイドライン 2015-腸管感染症-. 日本化学療法学会雑誌 Vol. 64, 2016年1号 (1月) : 31-65.
 
6) Cohen SH, Gerding DN, et al : Clinical practice guidelines for Clostridium difficile infection in adults : 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA). Infect Control Hosp Epidemiol. 2010 May ; 31 (5) : 431-55.
 
7) Surawicz CM, Brandt LJ, et al : Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections. Am J Gastroenterol. 2013 Apr ; 108 (4) : 478-98.
PubMed
8) Lacy BE, Mearin F, et al : Bowel disorders. Gastroenterology 2016 ; 150 : 1393-407.
 

7章 便秘 [ constipation ]

P.95 掲載の参考文献
1) Schiller LR : Chapter 9, Diarrhea and Constipation In Digestive Disease Self-Education Program 8. Sweetser S. ed. AGA, Bethesda 2016.
 
2) Lembo AJ : Chapter 19, Constipation. In Feldman M, Friedman LS, Brandt LJ. ed. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 10th ed (電子版). Elsevier, 2016.
 
3) 味村俊樹 : 機能性便排出障害型便秘症に対するバイオフォードバック療法の実際. 中島淳編 臨床医のための慢性便秘マネジメントの必須知識. pp176-82, 医薬ジャーナル社, 2015.
 
4) Mearin F, Lacy B.E, et al : Bowel Disorders. Gastroenterology 2016 ; 150 : 1393-1407.
 
5) 厚生労働省 : 「 日本人の食事摂取基準 (2015年版) 策定検討会」報告書. 平成26年3月28 日 (http://www.mhlw.go.jp/stf/shingi/0000041824.html).
 
6) 日本消化器病学会関連研究会, 慢性便秘の診断・治療研究会 (編集) : 慢性便秘症診療ガイドライン 2017. 2017, 南江堂.
 

8章 嚥下障害 [ dysphagia ]

P.105 掲載の参考文献
1) Devault KR : Symptoms of Esophageal Disease. In Sleisenger and Fordtran's Gastrointestinal and Liver Disease. Feldman M, Friedman LS, Brandt LJ. ed (. 電子版). Elsevier, 2016.
 
2) 日本摂食嚥下リハビリテーション学会医療検討委員会 : 嚥下造影の検査法 (詳細版). 日摂食嚥下リハ会誌 2014 ; 18 : 166-86.
 
3) Prasad GA, Alexander JA, et al : Epidemiology of eosinophilic esophagitis over three decades in Olmsted County, Minnesota. Clin Gastroenterol Hepatol. 2009 Oct ; 7 (10) : 1055-61.
PubMed
4) Fujishiro H, Amano Y, et al : Eosinophilic esophagitis investigated by upper gastrointestinal endoscopy in Japanese patients. J Gastroenterol 2011 ; 46 : 1142-4.
PubMed

9章 機能性ディスペプシア [ FD ]

P.117 掲載の参考文献
1) Stanghellini V, Chan FK, et al : Gastroduodenal disorders. Gastroenterology. 2016 May ; 150 (6) : 1380-92.
PubMed
2) Vanheel H, Carbone F, et al : Pathophysiological abnormalities in functional dyspepsia subgroups according to the Rome III criteria. Am J Gastroenterol. 2017 Jan ; 112 (1) : 132-140.
 
3) Carbone F, Holvoet L, et al : Rome III functional dyspepsia subdivision in PDS and EPS : recognizing postprandial symptoms reduces overlap. Neurogastroenterol Motil. 2015 Aug ; 27 (8) : 1069-74
 
4) Sugano K, Tack J, et al : Kyoto global consensus report on Helicobacter pylori gastritis. Gut. 2015 Sep ; 64 (9) : 1353-67.
PubMed
5) Moayyedi P, Soo S, et al : Eradication of Helicobacter pylori for non-ulcer dyspepsia. Cochrane Database Syst Rev 2011 ; 16 (2) : CD002096.
 
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7) Moayyedi P, Lacy B, Andrews C, et al : ACG and CAG Clinical guideline : Management of Dyspepsia. Am J Gastroenterol. 2017 Jul ; 112 (7) : 988-1013.
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10章 過敏性腸症候群 [ IBS ]

P.132 掲載の参考文献
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2) Beqtrup LM, Enqsbro AL, et al : A positive diagnostic strategy is noninferior to a strategy of exclusion for patients with irritable bowel syndrome. Clin Gastroenterol Hepatol. 2013 Aug ; 11 (8) : 956-62.
 
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4) Mearin F, Lacy B.E, et al : Bowel Disorders. Gastroenterology 2016 ; 150 : 1393-1407.
 
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11章 感染性腸炎 [ infectious enterocolitis ]

P.145 掲載の参考文献
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2) Dupont HL : Acute infectious diarrhea in immunocompetent adults. N Engl J Med. 2014 Apr 17 ; 370 (16) : 1532-40.
 
3) Riddle MS, DuPont HL, et al : ACG Clinical Guideline : Diagnosis, Treatment, and Prevention of Acute Diarrheal Infections in Adults. Am J Gastroenterol. 2016 May ; 111 (5) : 602-22.
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12章 消化器癌ポプリ [ potpourri : ごった煮 ]

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1) Andrici J, Hu H. S., et al : Facial flushing response to alcohol and the risk of esophageal squamous cell carcinoma : A comprehensive systematic review and meta-analysis. Cancer Epidemiol. 2016 Feb ; 40 : 31-8.
 
2) Yokoyama A, Oda J, et al : A health-risk appraisal model and endoscopic mass screening for esophageal cancer in Japanese men. Dis Esophagus. 2013 Feb-Mar ; 26 (2) : 148-53.
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3) Maguchi H, Tanno S, et al : Natural histor y of branch duct intraductal papillary mucinous neoplasms of the pancreas : A multicenter study in Japan. Pancreas. 2011 Apr ; 40 (3) : 364-70.
 
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5) Tanaka M, Castillo C. F., et al : Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas. Pancreatology. 2017 Sep - Oct ; 17 (5) : 738-53.
 
6) Huxley R, Ansary-Moghaddam A, et al : Type-II diabetes and pancreatic cancer : a metaanalysis of 36 studies. Br J Cancer. 2005 Jun 6 ; 92 (11) : 2076-83.
 

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