臨床腫瘍学 CLINICAL ONCOLOGY I・II Second edition (日本臨床腫瘍研究会編)

出版社: 癌と化学療法社
著者:
発行日: 1999-02-26
分野: 臨床医学:一般  >  癌/腫瘍一般
ISBN: 9784906225361
電子書籍版: 1999-02-26 (改訂第1版第1刷)
電子書籍
章別単位で購入
ブラウザ、アプリ閲覧

16,500 円(税込)

商品紹介

今回のsecond editionでは、全体をカバーするよう注意し、編集した。(序文より)

目次

  • 表紙
  • 序文
  • 執筆者一覧
  • レビュアー一覧
  • 目次
  • I. Principles of oncology
  • 1. 臨床腫瘍医学からみたがん ( 細胞 ) の特性
  • 2. がんの分子生物学
  • 3. 発がん機構
  • 4. 発がん因子
  • 1. ウイルス
  • 2. 化学因子
  • 3. 物理因子
  • 4. ホルモン
  • 5. がん遺伝子
  • 1. がん遺伝子・がん抑制遺伝子
  • 2. DNA複製および損傷修復と発がん
  • 6. 染色体異常
  • 7. 細胞がん化のシグナル伝達
  • 8. アポトーシス
  • 9. 細胞周期
  • 10. 血管新生
  • 11. 転移
  • 12. がん細胞の分化誘導と核内レチノイン酸レセプター
  • 13. 疫学
  • 14. がん遺伝学
  • 15. 腫瘍免疫
  • 16. 分子病理学
  • 17. がん予防
  • 1. 喫煙とがん
  • 2. がんと食餌, がんとホルモン, がん予防薬 etc
  • 18. 腫瘍診断学
  • 1-1. 内視鏡診断学 ( 消化器 )
  • 1-2. 内視鏡診断学 ( 呼吸器 )
  • 2. 画像診断 ( X線, CT, MRI, 超音波 )
  • 3. 腫瘍マーカー
  • 4. がんの病理診断の実際
  • 5. 腫瘍と外科病理
  • 19. がん検診
  • 20. 外科療法
  • 21. 放射線療法
  • 22. Interventional radiology
  • 23. がん化学療法
  • 24. がんの内分泌療法
  • 25. がんに対するBRM療法
  • 26. 抗がん剤開発
  • ( 基礎 ) ヒト培養がん細胞パネルによるスクリーニングを中心に
  • ( 臨床 )
  • 27. 抗がん剤と薬理動態
  • a) PK / PD
  • b) アルキル化剤
  • c) プラチナ誘導体の薬物動態
  • d) 代謝拮抗剤
  • e) トポイソメラーゼ阻害剤
  • f) 微小管阻害剤
  • g) 分化誘導剤
  • h) その他 ( 新しい抗がん剤を含む )
  • 28. 薬剤耐性
  • 29. 臨床試験
  • 30. がん治療におけるインフォームド・コンセント - 臨床試験でのインフォームド・コンセントの在り方 -
  • 31. 新GCPについて
  • 32. がん医療の経済
  • 33. 腫瘍学における情報伝達
  • 34. がん診療と報道 - 近藤理論に対するマスコミの立場を中心に -
  • 35. がん診療と倫理 - 臨床研究におけるプラシーボ対照の倫理性について - アメリカ医師会の指針案をもとに考える
  • 36. 臨床試験研究とその研究体制の在り方
  • 37. 新しいがん治療
  • 1. 重イオン・陽子線治療
  • 2. レーザー光化学治療
  • 3. 術中照射
  • 4. 遺伝子治療
  • 5. 内視鏡治療
  • 消化器
  • 呼吸器
  • 表紙
  • 目次
  • II. Practice of oncology
  • 38. 頭頸部がん
  • 39. 肺癌
  • 1. 小細胞肺癌
  • 2. 非小細胞肺癌
  • 40. 縦隔腫瘍
  • 41. 食道癌
  • 内科領域
  • 外科領域
  • 42. 乳癌
  • 43. 胃癌
  • 内科
  • 外科
  • 44. 結腸・直腸癌
  • 45. 肝癌
  • 46. 膵癌
  • 内科
  • 外科
  • 47. 胆道系がん
  • 48. 腎・尿路上皮癌
  • 1. 腎細胞癌
  • 2. 尿路上皮癌
  • 49. 前立腺癌
  • 50. 精巣腫瘍
  • 51. 子宮頸癌・外陰癌
  • 1. 子宮頸癌
  • 2. 外陰癌
  • 52. 子宮体癌
  • 53. 卵巣腫瘍・絨毛癌
  • 54. 悪性骨軟部腫瘍の治療
  • 55. 皮膚癌
  • 1. 悪性黒色腫
  • 2. 皮膚癌
  • 56. 脳腫瘍
  • 57. 内分泌系腫瘍
  • 58. ( 性腺外 ) 胚細胞腫瘍
  • 59. 小児固形がん
  • 60. 小児白血病・リンパ腫
  • 61. 白血病と類縁疾患
  • 62. 悪性リンパ腫
  • 1. ホジキン病
  • 2. 非ホジキンリンパ腫
  • 63. 多発性骨髄腫
  • 64. 原発不明がん
  • 65. HIV感染とがん
  • 66. 腫瘍随伴症候群
  • 67. がん性漿膜水
  • 1. 悪性胸水
  • 2. 心嚢炎
  • 3. がん性腹膜炎・がん性腹水
  • 68. 転移がんの治療
  • 1. 肺転移
  • 2. 肝転移外科治療
  • 3. 骨転移
  • 4. 脳転移
  • 69. 腫瘍関連緊急対策
  • 1. 上大静脈症候群
  • 2. 悪性腫瘍に伴う高カルシウム血症
  • 3. 脊髄損傷
  • 4. 消化管悪性腫瘍に対する緊急手術
  • 5. 泌尿器科的対策
  • 6. がん関連感染症
  • 70. 支持療法
  • 1. 造血幹細胞移植
  • 2. 化学療法薬物有害反応の対策
  • 3. 栄養対策
  • 4. がん性疼痛対策
  • 5. 外科手術と機能温存 ( QOLも含む )
  • 71. がん看護学
  • 1. 総論
  • 2. がん患者のリハビリテーション発声
  • 3. ストーマレハビリテーション
  • 72. サイコオンコロジー
  • 73. がん緩和医療学
  • 74. がん治療とQuality of Life
  • 付 : Revised Common Toxicity Criterias ( CTC )
  • 索引
  • 奥付

この書籍の参考文献

参考文献のリンクは、リンク先の都合等により正しく表示されない場合がありますので、あらかじめご了承下さい。

本参考文献は電子書籍掲載内容を元にしております。

P.12 掲載の参考文献
16) Greenblatt MS, Bennett WP, Hollstein M, et al: Mutations in the p 53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis. Cancer Res. 54: 4855-4878, 1994.
19) Kawajiri K, Eguchi H, Nakachi K, et al: Association of CYP 1 A 1 germ line polymorphisms with mutations of the p 53 gene in lung cancer. Cancer Res. 56: 72-76, 1996.
26) Seto M, Yamamoto K, Iida S, et al: Gene rearrangement and overexpression of PRAD in lymphoid malignancy with t (11;14) (q 13;q32) translocation. Oncogene 7: 1401-1406, 1992.
33) Gross L: Intradermal immunization of C 3 H mice against a sarcoma that originated in an animal of the same line. Cancer Res. 3: 326-333, 1943.
34) Foley EJ: Antigenic properties of methylcholanthrene-induced tumors in mice of the strain of origin. Cancer Res. 13: 835-837, 1953.
35) Prehn RT, Main JM: Immunity to methylcholanthrene-induced sarcomas. J. Natl. Cancer Inst. 18: 769-778, 1957.
39) Inoue H, Li J, Honda M, et al: Expression of MAGE-1, -2, -3 mRNA in gastric carcinoma. Med. Sci, Res. 22: 793-794, 1994.
51) Markowitz S, Wang J, Myeroff L, et al: Inactivation of the Type II TGF-β receptor in colon cancer cells with microsatellite instability. Science 268: 1336-1338, 1995.
P.25 掲載の参考文献
1) 豊島久真男, 黒木登志夫 (編集代表) : (がんのバイオサイエンス1~5巻) , 東大出版会, 1991.
1) Tooze J (ed) : "Molecular Biology of Tumor Virus", Cold Spring Habor Laboratories, 1973.
2) Weiss R, Teichi N, Varmus H, et al (eds) : "Molecular Biology of Tumor Virus", 2nd editon, RNA Tumor Viruses", 1982;Supplements and Appendixes, Cold Spring Harbor Laboratories, 1985.
2) 豊島久真男・他 (編) : 癌解明への新しいアプローチ, 最近医学, 1993年増刊.
6) Witkowski JA : The inherited character of cancer-a historical survey. Cancer Cell 2 : 229-257, 1990.
9) Knudson AG, Stanbridge EJ, Sugimura T, et al(eds) : “Genetic Basis for Carcinogenesis;Tumor Suppressor Genes and Oncogenes”, Japan Scientific Societies Press, 1989.
P.35 掲載の参考文献
5) 林 慎一, 川尻 要: P450遺伝子の多型と発癌感受性. 代謝 28 (増刊号癌'91) : 11-19, 1991.
6) 真木寿治: 自然突然変異とDNA修復. 実験医学 15: 1932-1937, 1997.
16) 益谷央豪, 菅澤 薫, 花岡文雄: 真核細胞のヌクレオチド除去修復. 細胞工学 13: 40-49, 1994.
20) Fujiki H, Sueoka E, Komori A, et al: Tumor promotion and TNF-αgene expression by the okadaic acid class tumor promoters. Environ. Carcino. &Ecotox Revs. C 15 (1) : 40, 1997.
22) Tatematsu M, Furihata C, Katsuyama T, et al: Immunohistochemical demonstration of pyloric gland-type cells with low-pepsinogen isozyme l in preneoplastic and neoplastic tissues of rat stomachs treated with N-methyl-N '-nitro-N-nitrosoguanidine. J. Natl. Cancer Inst. 78: 771-777, 1987.
23) Tatematsu M, Nagamine Y, Farber E: Redifferentiation as a bases for remodeling of carcinogen-induced hepatocyte nodules to normal appearing liver. Cancer Res. 43: 5049-5058, 1983.
44) Hibi K, Takahashi T, Yamakawa K, et al: Three distinct regions involved in 3 p deletion in human lung cancer. Oncogene 7: 445-449, 1992.
45) Suzuki H, Takahashi T, Kuroishi T, et al: p53 mutations in non-small cell lung cancer in Japan: association between mutations and smoking. Cancer Res. 52: 734-736, 1992.
47) Kanjilal S, Strom SS, Clayman GL, et al: p53 mutations in nonmelanoma skin cancer of the head and neck: molecular evidence for field cancerization. Cancer Res. 5513604-3609, 1995.
P.45 掲載の参考文献
6) Koike K, Shirakata Y, Yaginuma K, et al: Oncogenic potential of hepatitis B virus. Mol. Biol. Med. 6: 15H60, 1989.
17) Faktor O, Shaul Y: The identification of hepatitis B virus X gene responsive elements reveals functional similarity of X and HTLV-1 tax. Oncogene 5: 867-872, 1990.
19) 鈴木健之, 吉田光昭: ヒトT細胞白血病ウイルス(HTLV) の制御因子Tax. 現代化学33 (増刊) : 175-181, 1997.
21) Takada S, Kido H, Koike K, et al: Interaction of hepatitis B virus X protein with a serine protease, tryptase TL 2, as an inhibitor. Oncogene 9: 341-348, 1994.
24) 高田等子, 小池克郎: B型肝炎ウイルスと肝発癌. 蛋白質核酸酵素 35: 2089-2099, 1990.
25) Wollersheim M, Debelka U, Hofschneider PH: Atransactivating function encoded in the hepatitis B virus X gene is conserved in the integrated state. Oncogene 3: 545-552, 1988.
P.56 掲載の参考文献
3) Tomatis L, Aitio A, Wilbourn J, et al: Human carcinogens so far identified. Jpn. J. Cancer Res. 78: 887-898, 1987.
13) Nakae D, Yoshiji H, Mizumoto Y, et al: High incidences of hepatocellular carcinomas induced by a choline deficient L-amino acid defined diet in rats. Cancer Res. 52: 5042-5045. 1992
14) Nakae D, Yoshiji H, Maruyama H, et al: Production of both 8-hydroxydeoxyguanosine in liver DNA and α-glutamyltransferase-positive hepatocellular lesions in rats given a choline-deficient, L-amino acid-defined diet. Jpn. J. Cancer Res. 81: 1081-1084, 1990.
15) Cheng KC, Cahill DS, Kasai H, et al: 8-Hydroxyguanine, un abandunt from of oxidative DNA damage, causes G→Tand A→Csubsitutions. J. Biol. Chem. 267: 166-172, 1992.
16) International Agency for Research on Cancer: IARC Monographs on the Evaluation of Carcinogenic Risk to Humans. Overall evaluation of carcinogenicity: An updating of IARC monographs vol. 1-42 (suppl. 7) , IARC, Lyon, France, 1987, pp. 297-308.
22) Saitho A, Kimura M, Takahashi R, et al: Most tumors in transgenic mice with human c-Ha-ras gene contained somatically activated transgenes. Oncogene 5: 1195-1200, 1990.
26) Park HS, Goodlad RA, Wright NA: The incidence of aberrant crypt foci and colonic carcinoma in dimethylhydrazine-treated rats varies in a site-specific manner and depends on tumor histology. Cancer Res. 57: 4507-4510,
P.61 掲載の参考文献
1) Thomassen MJ, Buoen LC, Brand I, et al: Foreign-body tumorigenesis in mice: DNA synthesis in surface-attached cells during preneoplasia. J. Natl. Cancer Inst. 61: 359-363, 1978.
3) Kane AB: Mechanisms of mineral fibre carcinogenesis. Mechanisms of fibre carcinogenesis. IARC Scientific Publications No. 140, IARC, Lyon, 1996, pp. 11-33.
9) IARC. IARC Monographs on the evaluation of carcinogenic risk of the chemicals to humans, some metals and metallic compounds. vol. 23, IARC, Lyon, 1980.
10) IARC. IARC Monographs on the Evaluation of Carcinogenic Risk of the Chemicals to Humans, Chromium, nickel and welding. vo1. 49, IARC, Lyon, 1990.
12) IARC. IARC Monographs on the Evaluation of Carcinogenic Risk of the Chemicals to Humans, Asbestos. vol. 14, IARC, Lyon, 1977.
13) IARC. IARC Monographs on the Evaluation of Carcinogenic Risk of the Chemicals to Humans, Silica and silicates. vol. 42, IARC, Lyon, 1987.
14) IARC. IARC Monographs on the Evaluation of Carcinogenic Risk of the Chemicals to Humans, Man-made mineral fibres and radon. vol. 43, IARC, Lyon, 1988.
16) IARC. IARC Monographs on the Evaluation of Carcinogenic Risk of the Chemicals to Humans, Silica, some silicates, coal dusts and para-aramid fibrils. vol. 68, IARC, Lyon, 1997.
17) IARC. IARC Monographs on the Evaluation of Carcinogenic Risk of the Chemicals to Humans, Wood dust and formaldehyde. voL 62, IARC, Lyon, 1995.
18) Tsukahara Y, Fukamatsu Y, Hirabayashi T, et al: Adenocarcinoma of the endometrium following prolonged use of an intrauterine device. Nippon sanka fujinka gakkai zasshi (Acta Obstetrica et Gynaecologica Japonica) 35: 339-343, 1983.
19) Baba N, Von Haam E: Squamous cell carcinoma of the rat endometrium produced by insertion of strings coated with paraffin and polymer. J. Natl. Cancer Inst. 47: 675-685, 1971.
20) Van Natta BW, Thurston JB, Moore TS: Silicone breast implants Is there cause for concern? Indiana Medicine 83: 184-185, 1990.
24) Fukushima S, Tanaka H, Asakawa E, et al: Carcinogenicity of uracil, a nogenotoxic chemical, in rats and mice and its rationale. Cancer Res. 52: 3789-3794, 1989.
27) Kuwashima Y, Nemoto N, Ishikawa T: Expression of proto-oncogenes and cytoskeletal actin gene in foreign body-induced murine sarcomas. In Vivo 7: 139-142, 1993.
P.71 掲載の参考文献
6) Zajchowski DA, Sager R, Webster L: Estrogen Inhibits the Growth of Estrogen Receptor-negative, but not Estrogen Receptor-positive, Human Mammary Epithelial Cells Expressing a Recombinant Estrogen Receptor. Cancer Res. 53: 5004-5011, 1993.
14) Paech K, Webb P, Kuiper GGJM, et al: Differential Ligand Activation of Estrogen Receptors ERαand ERβ at AP l Sites. Science 277: 1508-1510, 1997.
P.83 掲載の参考文献
3) Kinzer KW, Vogelstein B: Cancer-susceptibility genes. Gatekeepers and caretakers. Nature 386: 761, 1997.
4) Bos JL: Ras oncogenes in human cancer;areview. Cancer Res. 49: 4672-4689, 1989.
19) Greenblatt MS, Bennett WP, Hollstein M, et al: Mutations in the p 53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res. 54: 4855-4878, 1994.
20) Szabo CI, King MC: Population genetics of BRCA I and BRCA 2. Am. J Hum. Genet. 60: 1013-1020, 1997.
22) Rubinfeld B, Souza B, Albert I, et al: Association of the APC gene product withβ-catenin. Science 262: 1731-1734, 1993.
26) Heldin CH, Miyazono K, ten Dijke P: TGF-βsignalling from cell membrane to nucleus through SMAD proteins. Nature 390: 465-471, 1997.
31) Markowitz S, Wang J, Myeroff L, et al: Inactivation of the type II TGF-βreceptor in colon cancer cells with microsatellite instability. Science 268: 1336-1338, 1995.
P.95 掲載の参考文献
3) Suzuki M, Savoysky E, Izuta S, et al: RNA priming coupled with DNA synthesis on natural template by calf thymus DNA polymerase α-primase. Biochemistry 32: 12782-12792, 1993.
7) Savoysky E, Suzuki M, Simbulan C, et al: Immunopurified Rb protein inhibits SV 40 T-antigen dependent stimulation of DNA polymeraseα. Oncogene 8: 319-325, 1993.
8) Simbulan CMG, Suzuki M, Izuta S, et al: Poly (ADP) ribose stimulates DNA polymeraseαby physical association. J. Biol. Chem. 268: 93-99, 1993.
11) 松影昭夫: DNA複製とその調節. 東京大学出版会, 東京, 1995.
12) Kornberg A, Baker D: DNA replication (Second Ed.) . Freeman and Co, New York, 1991.
13) Wang TS-F: Cellular DNA polymerases. In: DNA Replication in Eukaryotic cells (ed. by DePamphilis ML) , Cold Spring Harbor Laboratory Press, New York, 1996, pp. 495-524.
14) Greider CW, Collins K, Autexier: DNA telomerases. In: DNA Replication in Eukaryotic cells (ed. by DePam- philis ML) , Cold Spring Harbor Laboratory Press, New York, 1996, pp. 619-638.
15) 久保田弓子, 滝沢温彦: S期誘導シグナルとDNA複製開始. DNA複製・修復と発癌 (松影昭夫編) , 羊土社, 東京, 1996, pp. 44-56.
16) 釣本敏樹: 複製開始領域の構成とその活性化機構. DNA複製・修復と発癌 (松影昭夫編) , 1996, 羊土社, 東京, pp. 57-68.
17) 吉田松年: 複製酵素の機能と制御. DNA複製・修復と発癌 (松影昭夫編) , 1996, pp. 81-89.
18) 中津可道, 田中亀代治: 除去修復機構とその欠損症, DNA複製・修復と発癌 (松影昭夫編) , 1996, 羊土社, 東京, pp. 131-139.
19) 池島三与子, 島田 隆: ミスマッチ修復の分子機構と発癌. DNA複製・修復と発癌 (松影昭夫編) , 羊土社, 東京, 1996, pp. 143-153.
20) Carothers AM: DNA damage, mutation, and repair. In: Encyclopedia of Cancer (ed. by Bertino JR) , Academic Press, New York and London, 1996, pp. 484-450.
21) Friedberg E, Walker G, Siede W: DNA repair and Mutagenesis. ASM Press, Washington, D. C., 1996.
22) Loeb L: A mutator phonotype may be required for multistage carcinogenesis. Cancer Res. 51: 3075-3079, 1991.
P.114 掲載の参考文献
1) Mitelman F, Kaneko Y, Berger R: Report of the committee on chromosome changes in neoplasia. In: HumanGene Mapping 1993, A Compendium (eds by Cuticchia AJ, Pearson PL) , Johns Hopkins Univ Press, Baltimore, 1994, pp. 773-812.
4) Chen Z, Chen S-J, Wang Z-Y: Retinoic acid and acute promyelocytic leukemia: amodel of targetting treat- ment for human cancer. CR Acad. Sci. sciences de la vie 317: 1135-1141, 1994.
5) 阿部達生, 鎌田七男, 桜井雅温 (編) : 腫瘍染色体アトラス, 南江堂, 東京, 1986, pp. 27-51.
7) Holmquist GP: Chromosome bands, their chromatin flavors, and their functional features. Am. J. Hum Genet. 1: 17-37, 1992.
14) Cimino G, Rapanotti MC, Biondi A, et al: Infant acute leukemias show the same biased distribution of ALL lgene breaks as topoisomerase II related secondary acute leukemias. Cancer Res. 57: 2879-2883, 1997.
16) 阿部達生 (編) : 造血器腫瘍アトラス. 形態, 免疫, 染色体と遺伝子, 日本医事新報社, 東京, 1991, pp. 1-162.
21) Nowell PC: Chromosome changes and the clonal evolution of cancer. In: Chromosome and Cancer (ed by German J) , John Wiley&Sons, New York, 1974, pp. 267-285.
22) de Grouchy J, Turleau C: Clonal evolution in the myeloid leukemias. In: Chromosome and Cancer (ed by German J) , John Wiley&Sons, New York, 1974, pp. 287-311.
23) Nakai H, Misawa S, Toguchida J, et al: Frequent p53 gene mutations in blast crisis of chronic myelogeneous leukemia, especially in myeloid crisis harvoring loss of a chromosome 17p. Cancer Res. 52: 6588-6593, 1992.
37) Le Beau MM, Espinosa III R, Davis EM, et al: Cytogenetic and molecular delineation of a region of chromosome 7 commonly deleted in malignant myeloid diseases. Blood 88: 1930-1935, 1996.
50) Knutsen T, Veldman T, Padilla-Nash H, et al: Spectral karyotyping: Chromosomes in color. Applied Cytogenetics 23: 26-32, 1997.
51) Jenkins RB, Le Beau MM, Kraker WJ, et al: Fluorescence in situ hybridization: Asensitive method for trisomy 8 detection in bone marrow specimens. Blood 79: 3307-3315, 1992.
57) Lengauer C, Riethman HC, Speicher MR, et al: Metaphase and interphase cytogenetics with Alu-PCR-amplified yeast artificial chromosome clones containing the BCR gene and the protooncogenes c-raf-1, c-fms, and c-erbB-2. Cancer Res. 52: 2590-2596, 1990.
67) Knudson AG Jr: Hereditary cancer, oncogenes, and antioncogenes. Cancer Res. 45: 1437-1443, 1985.
P.129 掲載の参考文献
21) Bos J: ras oncogenes in human cancer: areview (published erratum appears in Cancer Res. 1990 Feb 15;50 (4) : 1352) . Cancer Res. 49: 4682-4689, 1989.
P.147 掲載の参考文献
8) 杭田慶介: Caspaseとアポトーシス. 日癌会56回総会記: 22, 1997.
32) Paddenberg R, Wulf S, Weber A, et al: Internucleosomal DNA fragmentation in cultured cells under conditions reported to induce apoptosis may be caused by mycoplasma endonucleases. Eur. J Cell Biol. 71: 105-119, 1996.
41) Ahmad M, Srinivasula SM, Wang L, et al: CRADD, a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP. Cancer Res. 57: 615-619, 1997.
56) Li WW, Fan J, Hochhauser D, et al: Overexpression of p21 wafl leads to increased inhibition of E2Pl phosphorylation and sensitivity to anticancer drugs in retinoblastoma-negative human sarcoma cells. Cancer Res. 57: 2193-2199, 1997.
57) Englert C, Maheswaran S, Garvin AJ, et al: Induction of p21 by the Wilms 'tumor suppressor gene WT1. Cancer Res. 57: 1429-1434, 1997.
76) Michael JM, Lavin MF, Watters DJ: Resistance to radiation-induced apoptosis in Burkitt 's lymphoma cells is associated with defective ceramide signaling. Cancer Res. 57: 3600-3605, 1997.
77) Chmura SJ, Nodzenski E, Beckett MA, et al: Loss of ceramide production confers resistance to radiationinduced apoptosis. Cancer Res. 57: 1270-1275, 1997.
95) Shibata Y, Takiguchi H, Tamura K, et al: Stimulation of interleukin-1 beta-converting enzyme activity during growth inhibition by CPT-11 in the human myeloid leukemia ce田ine K562. Biochem. Mol. Med. 57: 25-30, 1996.
97) Goldwasser F, Bae I, Fornace AJ Jr, et al: Differential GADD45, P21CIP1/WAF1, MCL-1 and topoisomerase II gene induction and secondary DNA fragmentation after camptothecin-induced DNA damage in two mutant p53 human colon cancer cell lines. Oncol. Res. 8: 317-323, 1996.
101) Yoshida A, Takauji R, Inuzuka M, et al: Role of serine and ICE-like proteases in induction of apoptosis by etoposide in human leukemia HL-60 cells. Leukemia 10: 821-824, 1996.
104) Skladanowski A, Larsen AK: Expression of wild-type p53 increases etoposide cytotoxicity in MI myeloidleukemia cells by facilitated G2 to M transition: implications for gene therapy. Cancer Res. 57: 818-823, 1997.
105) Sebestyen A, Mihalik R, Petak I, et al: Modulation of apoptosis signaling in etoposide-treated lymphoma cells. Anticancer Res. 17: 2609-2614, 1997.
108) Ibrado AM, Huang Y, Fang G, et al: Bcl-xL overexpression inhibits taxol-induced Yama protease activity and apoptosis. Cell Growth Differ. 7: 1087-1094, 1996.
110) Blagosklonny MV, Schulte T, Nguyen P, et al: Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway. Cancer Res. 56: 1851-1854, 1996.
111) Huang TS, Shu CH, Yang WK, et al: Activation of CDC 25 phosphatase and CDC 2 kinase involved in GL331-induced apoptosis. Cancer Res. 57: 2974-2978, 1997.
120) Kim CN, Wang X, Huang Y, et al: Overexpression of Bcl-X (L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis. Cancer Res. 57: 3115-3120, 1997.
122) Yoshida A, Ueda T: The mechanism of apoptosis induced by anticancer agents in human leukemia cells. Nippon Rinsho 54: 1822-1827, 1996.
124) Bullock G, Ray S, Reed JC, et al: Intracellular metabolism of Ara-C and resulting DNA fragmentation and apoptosis of human AML HL-60 cells possessing disparate levels of Bcl-2 protein. Leukemia 10: 1731-1740, 1996.
P.159 掲載の参考文献
P.177 掲載の参考文献
6) Polverini PJ, Leibovich SJ: Induction of neovascularization in vivo and endothelial proliferation in vitro by tumor-associated macrophage. Lab. Invest. 51: 635-642, 1984.
16) Hori A, Sasada R, Matsutani E, et al: Suppression of solid tumor growth by immunoneutralizing monoclonal antibody against human basic fibroblast growth factor. Cancer Res. 51: 6180-618, 1991.
18) Okamura K, Morimoto A, Hamanaka R, et al: Amodel system for tumor angiogenesis: involvement of transforming growth factor-α in tube formation of human microvascular endothelial cells induced by esophageal cancer cells. Biochem. Biophys. Res. Commun. 186: 1471-1479, 1992.
22) Shono T, Ono M, Izumi H, et al: Involvement of the transcription factor NF-πB in tubular morphogenesis of human microvascular endothelial cells by oxidative stress. Mol. Cell. Biol. 16: 4231-4239, 1996.
23) Huang S, Xie K, Bucana CD, et al: Interleukin 10 suppresses tumor growth and metastasis of human melanoma cells: potential inhibition of angiogenesis. Clin. Cancer Res. 2: 1969-1979, 1996.
26) Sidky YA, Borden EC: Inhibition of angiogenesis by interferons: effects on tumor-and lymphocyte-inducedvascular responses. Cancer Res. 47: 5155-5161, 1987.
34) Yeo T-K, Dvorac HF: Tumor-stroma. Diagnostic Immunopathology (ed. by Colvin RB, et al) , Raven Press. New York, 1995.
36) Zagzag D, Friedlander DG, Miller DC, et al: Tenascin expression in astorocytoma correlates with angiogenesis. Cancer Res. 55: 907-914, 1995.
42) Ueno H, Nakamura H, Inove M, et al: Expression and tissue localization of membrane-types 1, 2 and 3 matrix metalloproteinases in human invasive breast carcinomas. Cancer Res. 57: 32055-2060, 1997.
43) Millauer D, Coughi MP, Plate KH, et al: Dominan-negative inhibition of Flk-1 suppress the growth of many tumor type in vivo. Cancer Res. 56: 1615-1620, 1996.
44) Strawn LM, Mcmahon G, App H, et al: Flk-1 as a target for tumor growth inhibitor. Cancer Res. 56: 3540-3545, 1996.
49) Gately S, Twardowski P, Stack MS, et al: Human prostate carcinoma cells express enzymatic activity that converts human plasminogen to the angiogenesis inhibitor, angiostatin. Cancer Res. 56: 4887-4890, 1996.
52) Henrik Sandvad Rasmussen: Preclinical and early clinical data with batimastat and marimastat, two novel matrix metalloproteinase inhibitors. Proc. Angiogenesis Antagonists, 1996.
56) Fine HA, Loeffler JS, Kyritsis A et al: Aphase I trial of the anti-angiogenic agent, thalidomide, in androgen independent prostate cancer. Proc. Am. Soc. Clin. Oncol. 16: 385 a, 1997.
57) AACR meeting Abst. #2721, 1996.
59) Gutheil J, Campbell TN, Pierce PR et al: Phase l study of vitaxin, an anti-angiogenic humanized monoclonal antibody to vascular integrin{alpha}{nu}{beta}3. Proc. Am. Soc. Oncol. 17: 215 a, 1998.
61) Kohn EC, Reed E, Sarosy E, et al: Aclinical investigation of a cytotoxic calcium influx inhibitor in patients with refractory cancers. Cancer Res. 56: 569-573, 1996.
65) Johnston MR, Mullen JBM, Pagura M et al: AG 3340, a novel metalloproteinase (MMP) inhibitor, decreases growth and metastases of orthotopic human lung cancer in a nude rat preclinical model system. Proc. Am. Ass. Cancer Res. 39: 302, 1998.
P.194 掲載の参考文献
2) Tsuruo T, Yamori T, Naganuma K, et al: Characterization of metastatic clones derived from a metastatic variant of mouse colon adenocarcinoma. Cancer Res. 43: 5437-5442, 1983.
3) Morikawa K, Walker SM, Jessup JM, et al: ln vivo selection of highly metastatic cells from surgical specimens of different primary human colon carcinomas implanted into nude mice. Cancer Res. 48: 1943-1948, 1988.
4) 入村達郎: 癌転移の分子機構-序論. 実験医学 7: 525-526, 1989.
5) Hart I, Fidler IJ: An in vitro quantitative assay for tumor cell invasion. Cancer Res. 38: 3218-3224, 1978.
7) Kramer RH, Bensch KK, Wong J: Invasion of reconstituted basement-membrane matrix by metastatic tumor cells. Cancer Res. 46: 1080-1089, 1986.
8) Akedo H, Shinkai K, Mukai M, et al: Interaction of rat ascites hepatoma cells with cultured mesothelial cell layers: Amodel for tumor invasion, Cancer Res. 46: 2416-2422, 1986.
9) del Regata JA: Pathways of metastatic spread of malignant tumors. Semin. Oncol. 4: 33-38, 1977.
10) Fisher B, Fisher ER: The interrelationship of hematogenous and lymphatic tumor cell dissemination. Surg. Gyneco1. Obstet. 122: 791-798, 1966.
12) Ewing J: A Treatise on Tumors. 3rd Ed, WB Saunders, Philadelphia, 1920.
13) Paget S: The distribution of secondary growths in cancer of the breast. Lancet 1: 571-573, 1989.
14) Zeidman I, Buss JM: Experimental studies on the spread of cancer in the lymphatic system: effectiveness of the lymph node as a barrier to the passage of emnonic tumor cells. Cancer Res. 14: 403-410, 1954.
16) Hill RP: Metastasis. In The Basic Science of Oncology (ed by Tannock IF, Hill RP) , Pergamon Press, New York, 1987, pp. 160-175.
17) Tarin D, Price JE: Influence of microenvironment and vascular anatomy on "metastatic" colonization potential of mammary tumors. Cancer Res. 41: 3604-3609, 1981.
18) Hart IR, Fidler IJ: Role of organ selectivity in the determination of metastasis pattern of B 16 melanoma. Cancer Res. 41: 1282-1287, 1981.
20) Hujanen ES, Terranova VP: Migration of tumor cells to organ-derived chemoattractants. Cancer Res. 45: 3517-3521, 1985.
22) Sugarbaker EV: Patterns of metastasis in human malignancy. Cancer Biol. Rev. 2: 235-278, 1981.
27) Vogelstein B, Fearon ER, Hamilton SR, et al: Clonal analysis using recombinant DNA probes from the Xchromosome. Cancer Res. 47: 4806-4813, 1987.
28) Nowell PC: Mechanisms of tumor progression. Cancer Res. 48: 2203-2207, 1988.
29) Nicolson GL: Tumor cell instability, diversification, and progression to the metastatic phenotype: From oncogene to oncofetal expression. Cancer Res. 47: 1473-1487, 1987.
32) Dear TN, Ramshow JA, Kefford RF: Differential expression of a novel gene, WDNM 1, in nonmetastatic rat mammary adenocarcinoma cells. Cancer Res. 48: 5203-5209, 1989.
33) Dear TN, McDonald DA, Kefford RF: Transcriptional down-regulation of a rat gene, WDNM 2, in metastatic DNMBA-8 cells. Cancer Res. 49: 5323-5328, 1989.
38) Toh Y, Pencil SD, Nicolson GL: Anovel candidate metastasis-associated gene, mtα 1, differentially expressed in highly metastatic mammary adenocarcinoma cell line. J. Biol. Chem. 268: 22958-22967, 1994.
42) Fidler IJ: Critical factors in the biology of human cancer metastasis. Cancer Res. 50: 6130-6138, 1990.
43) Morikawa K, Walker SM, Nakajima M, et al: Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice. Cancer Res. 48: 6863-6871, 1988.
47) Weidner LA, Carroll PR, Flax J, et al: Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am. J. Pathol. 143: 401-409, 1993.
53) Shimoyama Y, Nagafuchi A, Fujita S, et al: Cadherin dysfunction in a human cancer cell line: Possible involvement of loss ofα-catenin expression in reduced cell-cell adhesiveness. Cancer Res. 52: 5770-5774, 1992.
54) Hirano S, Kimoto N, Shimoyama Y, et al : Identification of a neural α-catenin as a key regulator of cadherin function and multicellular organization. Cell 70: 293-301, 1992.
58) Inohara H, Raz A: Functional evidence that cell surface Galectin-3 mediates homotipic cell adhesion. Cancer Res. 55: 3267-3271, 1995.
59) Ligtenberg MJL, Buijs F, Vos HL, et al: Suppression of cellular aggregation by high levels of episialin. Cancer Res. 52: 2318-2324, 1992.
60) Shimoyama Y, Hirohashi S: Expression of E-and P-cadherin in gastric carcinomas. Cancer Res. 51: 2185-2192, 1991.
61) Shiozaki H, Tahara H, Oka H, et al: Expression of immunoreactive E-cadherin adhesion molecules in human cancers. Am. J. Pathol. 139: 17-23, 1991.
62) Schipper JH, Frixen UH, Behrens J, et al: E-cadherin expression in squamous cell carcinomas of head and neck: inverse correlation with tumor dedifferentiation and lymph node metastasis. Cancer Res. 51: 6328-6337, 1991.
63) Umbas R, Isaacs WB, Aalders TW, et al: Decreased expression of E-cadherin in high grade prostate cancer. Cancer Res. 52: 5104-5108, 1992.
65) Bringuier PP, Umbas R, Schaafama HE, et al: Decreased E-cadherin immunoreactivity correlates with poor survival in patients with bladder tumors. Cancer Res. 53: 3241-3245, 1993.
67) Shiozaki H, Iihara K, Oka H, et al: Immunohistochemical detection ofα-catenin expression in human cancer. Am. J. Pathol. 144: 1-8, 1994.
69) Zotter S, Philomena CH, Lossnitzer A, et al: Tissue and tumor distribution of human polymorphic epithelial mucin. Cancer Rev. 11-2: 55-101, 1988.
71) Liotta LA: Tumor invasion and metastases-Role of the extracellular matrix. Cancer Res. 46: 1-7, 1986.
72) Fidler IJ: Metastasis: Quantitative analysis of distribution and fate of tumor emboli labeled with 125I-5-iod-2'-deoxyuridine. J. Natl. Cancer Inst. 45: 773-782, 1970.
73) Hill RP, Young SD, Cillo D, et al: Metastatic cell phenotypes: Quantitative studies using the experimental metastasis assay. Cancer Rev. 5: 118-151, 1986.
74) Hilgard P: Anticoagulants and tumor growth: Pharmacological consideration. In: Cancer Invasion and Metastasis: Biologic and Therapeutic Aspects (ed by Nicolson GL, Milas L) , Raven Press, New York, 1984, pp. 353-360.
79) Fukishima K, Hirota M, Terasaki PI, et al: Characterization of sialosylated Lewisx as a new tumor-associated antigen. Cancer Res. 44: 5279-5285, 1984.
80) Ruoslahti E, Gianocotti FG: Integrins and tumor cell dissemination. Cancer Cells 1: 119-126, 1989.
81) Haynes BF, Liao HX, Patton KL: The transmembrane hyaluronate receptor (CD 44) : Multiple functions, multiple forms. Cancer Cells 3: 347-350, 1991.
82) Hanna N: Role of natural killer cells in host defense against cancer metastasis. In Cancer Invasion and Metastasis: Biologic and Therapeutic Aspects (ed by Nicolson GL, Milas L) , Raven Press, New York, 1984, pp. 309-319.
92) Takada A, Ohmori K, Yoneda Y, et al: Contribution of carbohydrate antigens sialyl Lewis A and sialyl Lewis X to adhesion of human cancer cells to vascular endothelium. Cancer Res. 53: 354-361, 1993.
94) Sacchi A, Falcioni R, Kennel SJ, et al: Ligand-induced phosphorylation of murine tumor surface protein (TSP-1) associated with metastasis phenotype. Cancer Res. 49: 2615-2620, 1989.
97) Nakamori S, Kameyama M, Imaoka S, et al: Increased expression of sialyl lewisxantigen correlates with poor survival in patients with colorectal carcinoma: Clinicopathological and immunohistochemical study. Cancer Res. 53: 3632-3637, 1993.
102) Albelda SM, Mette SA, Buck CA, et al: Integrin distribution in malignant melanoma: association of theβ3 subunit with tumor progression. Cancer Res. 50: 6757-6764, 1990.
104) Tomita Y, Saito T, Saito K, et al: Possible significance of VLA-4 (α4β1) for hematogenous metastasis of renal-cell cancer. Int. J. Cancer 60: 753-758, 1995.
109) Hofmann M, Rudy W, Zoller M, et al: CD 44 splice variant of glycoprotein confer metastatic behavior in rat. Cancer Res. 51: 5292-5297, 1991.
111) Rudy W, Hofmann M, Scfwartz-Albeyz R, et al: The two major CD 44 proteins expressed on a metastatic rat tumor cell line are derived from different splice variants: each one individually suffices to confer metastatic behavior. Cancer Res. 53: 1262-1268, 1993.
118) Honn KV, Tang DG, Grossi I, et al: Tumor cell-derived 12 (S) -hydroxyeicosatetraenoic acid induces microvascular endothelial cell retraction. Cancer Res. 54: 565-574, 1994.
120) Khokha R, Denhardt DT: Matrix metalloproteinases and tissue inhibitor of metalloproteinases: areview of their role in tumorigenesis and tissue invasion. Invasion Metastasis 9: 391-405, 1989.
121) Nakajima M, Chop AM: Tumor invasion and extracellular matrix degradative enzymes: regulation of activity by organ factors. Semin. Cancer Biol. 2: 115-127, 1991.
125) Zucker S, Lysik RM, Zarrabi MH, et al: Mr 92, 000 collagenase is increased in plasma of patients with colon cancer and breast cancer. Cancer Res. 53: 140-146, 1993.
127) Nomura H, Sato H, Seiki M, et al: Expression of membrane-type matrix metalloproteinase in human gastric carcinomas. Cancer Res. 55: 3263-3266, 1995.
142) Wang M, Steans M, Stearns ME: Identification of the receptor for a novel Mr 78, 000“lnvasion stimulating factor”from metastatic human prostatic PC-3 ML clones. Cancer Res. 54: 2492-2495, 1994.
145) Otto T, Birchmeier W, Schmit U, et al: Inverse relation of E-cadherin and autocrine motility factor receptor expression as a prognostic factor in patients with bladder carcinoma. Cancer Res. 54: 3120-3123, 1994.
156) Nakamori S, Yoshioka K, Kameyama M, et al: Increased expression of RHOAp 21 protein is involved in progression and metastasis of colorectal carcinoma. In: Recent Advances in Gastroenterological Carcinogenesis I (ed by Tahara E, Sugimachi K, Oohara T) , Monduzzi Editore, Bologna, 1996, pp. 901-904.
158) Fidler IJ: The evolution of biological heterogeneity in metastatic neoplasms. In: Cancer Invasion and Metastasis: Biologic and Therapeutic Aspects (ed by Nicolson GL, Milas L) , Raven Press, New York, 1984, pp. 5-30.
160) Yamori T, Iizuka Y, Takayama Y, et al: Insulin-like growth factor I induces tyrosine phosphorylation of a Mr 150, 000and Mr 160, 000 protein in highly metastatic mouse colon carcinoma 26 NL-17 cells. Cancer Res. 51: 5859-5865, 1991.
165) Hayashi N, Arakawa H, Nagase H, et al: Genetic diagnosis identifies occult lymph node metastases undetectable by the histopathological method. Cancer Res. 54: 3853-3856, 1994.
166) Mori M, Mimorti K, Inoue H, et al: Detection of cancer micrometastases in lymph nodes by reverse transcriptase-polymerase chain reaction. Cancer Res. 55: 3417-3420, 1995.
167) Sasaki A, Boyce BF, Story B, et al: Bisphonate risedrate reduces metastatic human breast cancer in bone in nude mice. Cancer Res. 55: 355-3557, 1995.
168) Yamaoka M, Yamamoto T, Sudo K, et al: Inhibition of tumor growth and metastasis of rodent tumor by the angiogenesis inhibitor O- (choroacetyl-carbamoyl) fumagillol (TNP-470 ; AGM-1470) . Cancer Res. 53: 4262-4267, 1993.
169) Tanaka T, Konno H, Baba S, et al: Prevention of hepatic metastasis of human colon cancer by angiogenesis inhibitor TNP-470. Cancer Res. 55: 836-839, 1995.
P.213 掲載の参考文献
1) 首藤紘一, 橋本祐一 (編) : 発癌と制癌の化学. 広川書店, 東京, 1990.
2) 穂積本男, 高久史麿 (編) : 癌細胞の分化誘導と制癌. ソフトサイエンス社, 東京, 1985.
3) 穂積本男, 斉藤政樹, 佐藤光信 (編) : 癌細胞の分化誘導とアポトーシス. 共立出版, 東京, 1995.
5) Maeda M, Ichikawa Y: Spontaneous development of macrophage-like cells in aculture ofof myeloid leukemia cells. Gann 64: 265-271, 1970.
17) Miyaura C, Abe E, Kuribayashi T, et al: 1α, 25-Dihydroxyvitamin D3 induces differentiation of human myeloid leukemia cells. Biochem. Biophys. Res. Commum. 101: 1131-1138, 1981.
20) "The Retinoids", 2nd ed,. eds. Sporn MB, Roberts AB, Goodman DS, Raven Press l994.
21) 首藤紘一 (編) : 「レチノイド」. 橋本祐一, 講談社サイエンティフィク, 1992.
26) Cippitelli M, Ye J, Viggiano V, et al: Retinoic acid-induced transcriptional modulation of the human interferon-γpromoter. J. Biol. Chem. 271: 26783-26793, 1996.
31) Imashuku S, Fossett MC III., Green AA: Characterization of adenosine cyclic 3 ': 5 '-monophosphate-binding proteins in human neuroblastoma. Cancer Res. 39: 3006-3013, 1979.
33) Itoh T, Miura K, Miki H, et al: β-Tubulin binds Src homology 2 domains through a region different from the thyrosine-phosphorylated protein-recognizing site. J. Biol. Chem. 271: 27931-27935, 1996.
35) Honma Y, Kasukabe T, Hozumi M: lnhibition of differentiation of cultured mouse myeloid leukemia cells by nonsteroidal antiinflammatory agents and counteraction of the inhibition by prostaglandin E. Cancer Res. 39: 2190-2194, 1979.
36) riffin J, Munroe D, Major P, et al: Induction of differentiation of human myeloid leukemia cells by inhibitors of DNA synthesis. Exp. Hematol. 10: 774-781, 1982.
40) Okabe-Kado J, Honma Y, Hayashi M, et al: Effects of histone fractions on induction of differentiation of cultured mouse myeloid leukemia cells. Cancer Lett. 41: 1997-2002, 1981.
44) Lopez-Boado YS, Klaus M, Dawson M, et al: Retinoic acid-induced expression of apolipoprotein D andconcomitant growth arrest in human breast cancer cells are mediated through a retinoic acid receptor RAR α-dependent signaling pathway. J. Biol. Chem. 271: 32106-32111, 1996.
47) Hashimoto Y, Shudo K: Retinoids and their nuclear receptors. Cell Biol. Rev. 25: 209-230, 1991.
52) Dawson MI, Elstner E, Kizaki M, et al: Myeloid differentiation mediated through retinoic acid receptor/retinoid
54) Tontonoz P, Singer S, Forman BM, et al: Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activatied receptor γ and the retinoid X receptor. Proc. Natl. Acad. Sci. USA 94: 237-241, 1997.
58) Bourguet W, Ruff W, Chambon P, et al: Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α. Nature 375: 377-382, 1995.
59) Renaud JP, Rochel N, Ruff M, et al: Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid. Nature 378: 681-689, 1995.
63) de The H, Chomienne C, Lanotte M, et al: The t (15: 17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptorαgene to a novel transcribed locus. Nature 347: 558-561, 1990.
64) Brown D, Kogan S, Lagasse E, et al: APMLRARαtransgene initiate murine acute promyelocytic leukemia. Proc. Natl. Acad. Sci. USA 94: 2552-2556, 1997.
65) 橋本祐一, 首藤紘一: PML-RARαの機能. 血液・腫瘍科 30: 74-78, 1995.
69) Metcalf D, Moore MAS, Warner NL: Colony formation in vitro by myelomonocytic leukemia cells. J. Natl. Cancer Inst. 43: 983-997, 1969.
73) Gamba-Vitalo C, Blair OC, Tritton TR, et al: Cytotoxicity and differentiating actions of adriamycin in WEHI-3BD+leukemia cells. Leukemia 1: 188-197, 1987.
78) Hozumi M: Anew approach to chemotherapy of myeloid leukemia cells by inducer of normal differentiation. Cancer Biol. Rev. 3: 153-211, 1982.
79) Koeffler HP, Bar-Eli M, Territo MC: Phorbol ester effect on differentiation of human myeloid leukemia cell lines blocked at different stages of maturation. Cancer Res. 41: 919-926, 1981.
80) Gianni AM, Presta M, Polli E, et al: In "Advances in Red Blood Cell Biology", Raven Press, 1982, pp. 279-287.
81) Minowada J: In "Human Lymphocyte Differentiation", INSERM SYMP No. 8, eds. Serrou B, Rosenfeld C, Elsevier Press, 1978, pp. 337-344.
83) Olsson IL, Breitman TR: Induction of differentiation of the human histocytic lymphoma cell line U-937 by retinoic acid and cyclic adenosine 3 ': 5 '-monophosphate-inducing agents. Cancer Res. 42: 3924-3927, 1982.
84) Olsson I, Gullberg U, Ivhed I, et al: Induction of differentiation of the human histiocytic lymphoma cell line U-937by 1α, 25-dihydroxycholcalciferol. Cancer Res. 43: 5862-5867, 1983.
86) Ohta M, Furukawa Y, Ide C, et al: Establishment and characterization of four human monocytoid leukemia cell lines (JOSK-1, -S, -M and-K) with capabilities of monocyte-macrophage lineage differentiation and constitutive production of interleukin 1. Cancer Res. 46: 3067-3074, 1986.
88) Hu F, Lesney PF: The isolation and cytology of two pigment cell strains from B 16 mouse melanomas. Cancer Res. 24: 1634-1643, 1964.
93) Sidell N: Retinoic acid-induced growth inhibition and morphologic differentiation of human neuroblastoma cells in vitro. J. Natl. Inst. 68: 589-596, 1981.
95) Littauer UZ, Palfrey C, Kimhi Y, et al: Induction of differentiation in mouse neuroblastoma cells. Natl. Cancer Inst. Monogr. 48: 333-337, 1978.
P.232 掲載の参考文献
1) Parkin DM, Whelan SL, Ferlay J, et al (eds) : Cancer Incidence in Five Continents, Vol. VII. IAR Scientific Publication No. 143, IARC, Lyon, 1997.
2) 花井 彩, 藤本伊三郎: 日本のがん罹患率とその推移. がん・統計白書-罹患/死亡/予後-1993 (富永祐民, 青木國雄, 花井 彩・他編) , 篠原出版, 東京, 1993, pp. 107-144.
3) 北川貴子, 津熊秀明, 大島 明・他: 1992年 (平成4年) 全国がん罹患数, 罹患率の推定. 地域がん登録の精度向上と活用に関する研究平成8年度研究班報告書 (大島明編) , 1997, pp. 32-44.
4) 黒石哲生, 広瀬加緒瑠, 田島和雄・他: 日本におけるがん死亡 (1950-1990) . がん・統計白書-罹患/死亡/予後-1993 (富永祐民, 青木國雄, 花井 彩・他編) , 篠原出版, 東京, 1993, pp. 1-105.
5) 厚生統計協会 (編) : 国民衛生の動向. 臨時増刊44 (9) : 50-59, 1997.
6) 北川貴子, 津熊秀明, 花井 彩・他: 1975-89年の全国罹患率 (推計値) に基づくがん罹患の将来推計. 厚生の指標43: 10-18, 1996.
7) Parkin DM, Muir CS, Whelan SL, et al (eds) : Cancer Incidence in Five Continents, Vol. VI. IARC Scientific Publication No. 120, IARC, Lyon, 1992.
8) 津熊秀明, 村上良介, 花井 彩・他: わが国における大腸癌の疫学. 外科57: 1-7, 1995.
9) 津熊秀明, 花井 彩, 北川貴子・他: 乳がん罹患の動向. CRC 2: 618-625, 1993.
10) Shimizu H, Mack TM, Ross RK, et al: Cancer of the gastrointestinal tract among Japanese and white immigrants in Los Angeles County. J. Natl. Cancer. Inst. 78: 223-228, 1987.
11) 藤本伊三郎, 花井 彩, 日山與彦・他 (編) : 大阪府におけるがんの罹患と死亡1963-1989. 篠原出版, 東京, 1993.
12) Fraumeni Jr JF, Devesa SS, Hoover RN, et al: Epidemiology of Cancer. Cancer, Principles&Practice of Oncology (ed by DeVita Jr VT, Hellman S, Rosenberg ST) , 4th Ed, Lippincott Company, Philadelphia, 1993, pp. 150-181.
14) 大島 明, 津熊秀明, 味木和喜子・他 (編) : 大阪府におけるがん患者の生存率の動向1975-89年. 篠原出版, 東京, 1998.
15) Hennekens CH, Buring JE: Epidemiology in Medicine. Little, Brown and Company, Boston, 1987.
16) Rothman KJ, Greenland S: Modern Epidemiology. Lippincott-Raven, Philadelphia, 1998.
17) Monson RR: Occupational Epidemiology. CRC Press, Florida, 1980, pp. 93-103.
P.242 掲載の参考文献
2) 山本 雅: がん遺伝子とがん抑制遺伝子. 南江堂, 東京, 1996.
3) Akiyama Y, Sato H, Yamada T, et al: Germline mutation of the hMSH 6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred. Cancer Res. 5713920-3923, 1997.
4) Palombo F, Iaccarino I, Nakajima E, et al: hMutSβ, a heterodimer of hMSH 2 and hMSH 3, binds to insertion/deletion loops in DNA. Curr. Biol. 6: 1181-1184, 1996.
6) Akiyama Y, Iwanaga R, Saitoh K, et al: Transforming growth factor-βtype II receptor gene mutations in adenomas from hereditary nonpolyposis colorectal cancer patients. Gastroenterology 112: 33-39, 1997.
P.252 掲載の参考文献
1) Old LJ: Cancer immunology: The search for specificity-G. H. A. Clowes memorial lecture. Cancer Res. 41: 361-375, 1981.
2) Lloyd KO, Old LJ: Iluman monoclonal antibodies to glycolipids and other carbohydrate antigens: Dissection of the human immune response in cancer patients. Cancer Res. 49: 3445-3451, 1989.
22) 高橋利忠, 上田龍三: 15. 単クローン抗体の治療への応用. がんと生体防御 (徳永徹編) , 東京大学出版会, 東京, 1994, pp190-203.
23) Byers VS, Rodvien R, Grant K, et al: Phase I study monoclonal antibody-ricin a chain immunotoxin xomazyme-791 in patients with metastatic colon cancer. Cancer Res. 49: 6153-6160, 1989.
P.260 掲載の参考文献
1) 菊地浩吉: 序論. 新病理学総論 (菊地浩吉, 吉木敬編) , 南山堂, 東京, 1993, pp. 1-13.
2) 前田 盛: 分子病理学. 病理と臨床 5: 2, 1997.
7) 安井 弥, 田原榮一: 蛋白質解析 (ウェスタンブロット法, Immunohistochemistry) . 分子生物学的アプローチによる癌研究プロトコール (横田 淳, 山本 雅編) . 羊土社, 東京, 1995, pp. 108-115.
8) 渡辺慶一, 中根一穂: 酵素抗体法改訂3版, 学術企画, 東京, 1992.
9) 尾上 均, 山崎 大, 磯崎耕次・他: in situ hybridization法. 遺伝子工学実験法 (渋谷正史, 横田崇編) , 中外医学社, 東京, 1994, pp. 319-328.
10) Radinsky R, Bucana CD, Ellis LM, et al: Arapid colorimetric in situ messenger RNA hybridization technique for analysis of epidermal growth factor receptor in paraffin-embedded surgical specimens of human colon carcinomas. Cancer Res. 53: 937-943, 1993.
11) 安西春幸: EGF受容体のin situ hybridization法による検出. [続]がんの浸潤・転移研究マニュアル (がん転移研究会編) , 金芳堂, 京都, 1997, pp. 229-231.
12) 松原謙一, 吉川 寛 (監修) : FISH実験プロトコール (細胞工学別冊実験プロトコールシリーズ) . 秀潤社, 東京, 1994.
13) 稲澤譲治: ホルマリン固定標本や剥離細胞を試料にしたFISH法による染色体異常の検出. 分子生物学的アプローチ による癌研究プロトコール (横田 淳, 山本 雅編) , 羊土社, 東京, 1995, pp. 232-242.
14) Yasui W, Ito H, Tahara E: DNA analysis of archival material and its application to tumour pathology. In "Diagnostic Molecular Pathology: APractical Approach" (eds. by Herrington CS, McGee JO ' D) . OxfordUniversity Press, Oxford, 1992, pp. 193-206.
15) Shinata D, Hawes D, Li Z-H, et al: Specific genetic analysis of microscopic tissue after selective ultravioletradiation fractionation and the polymerase chain reaction. Am. J Pathol. 141: 539-543, 1992.
16) 川村眞智子, 林 健志: PCR-SSCP. 臨床DNA診断法 (古庄敏行, 井村裕夫監修) , 金原出版, 東京, 1995, pp. 90- 97.
19) Horii A, Han H-J, Shimada M, et al: Frequent replication errors at microsatellite loci in tumors of patients with multiple primary cancers. Cancer Res. 54: 3373-3375, 1994.
22) 中村祐輔: ヒトがんでの遺伝子異常と遺伝子診断: 概説. 「がんと遺伝子-機能から診断・治療まで-」. 蛋白質核酸酵素 (増刊) 42: 1771-1715, 1997.
23) 三好康雄, 中村祐輔: ヒトがんでの遺伝子異常と遺伝子診断: 遺伝性腫瘍. 「がんと遺伝子-機能から診断・治療まで-」. 蛋白質核酸酵素 (増刊) 42: 1776-1722, 1997.
P.270 掲載の参考文献
1) 渡辺 昌, 山口直人: 肺癌はどこまで増え続けるか・またその予後は? Medical Practice 8: 1673-1680, 1991.
2) 平山 雄: 予防がん学: その新しい展開. メディサイエンス社, 東京, 1987.
3) Tsugane S, Watanabe S, Sugimura H, et al: Recent trends in different histological types of lung cancer in Tokyo based on Pathological Autopsy Records. Jpn. J. Cancer Res. 78: 162-169, 1987.
5) Doll R, H川AB: Smoking and carcinoma of the lung. BMJ 2: 739, 1950.
6) 喫煙と健康, 喫煙と健康問題に関する報告書第2版. 厚生省 (編) , 東京, 健康体力づくり事業財団, 1993.
8) Watanabe S, Tsugane S, Arimoto H, et al: Trend of lung cancers in the National Cancer Center of Japan and comparison with that of Japanese Pathological Autopsy Records. Jpn. J. Cancer Res. 78: 460-466, 1987.
9) Sugimura H, Watanabe S, Tsugane S, et al: Case-control study on histologically determined multiple primary lung cancer. J. Natl. Cancer Inst. 79: 435-441, 1987.
10) Suzuki T, Sobue T, Fujimoto I, et al: Association of adenocarcinoma of the lung with cigarette smoking by grade of differentiation and subtype. Cancer Res. 50: 444-447, 1990.
11) US Environmental Protection Agency: Respiratory Health Aspects of Passive Smoking. Lung Cancer and other Disorders. Washington, EPA, 1992.
13) 中地 敬, 今井一枝: 喫煙と肺癌の遺伝的感受性. Pharma Med. 11: 103-108, 1994.
14) Kobayashi Y, Arimoto H, Watanabe S: Occurrence of multiple primary cancer at the National Cancer Center Hospital, 1966-1990. Jpn. J. Clin. Oncol. 21: 233-251, 1991.
16) 渡辺 昌: 膵がんの疫学. 消化器科 10: 611-617, 1989.
17) Hartge P, Silverman D, Hoover R, et al: Changing cigarette habits and bladder cancer risk: Acase-control study. J. Natl. Cancer Inst. 78: 1119-1125, 1987.
18) Vecchia CL, Negri E, D ' Avanzo, et al: Smoking and renal cell carcinoma. Cancer Res. 50: 5233-5233, 1990.
24) 山口直人, 渡辺 昌: CANSAVEによる肺癌の将来予測. CRC 1: 132-137, 1992.
25) 渡辺 昌: 海外におけるがんの薬物予防. CRC 1: 186-198, 1992.
27) 平山 雄: 喫煙と疾病, 大規模コホート研究の総括. Pharma Med. 11: 19-32, 1994.
29) Goto K, Watanabe S: Economy and Diseconomy of Tobacco. Tob. Control. (in press)
30) 厚生省保健医療局健康増進栄養課 (監) : 喫煙対策Q&A. 保健同人社, 東京, 1994.
35) 中村正和: 母子保健の立場からみた喫煙問題. Pharma Med. 11: 81-88, 1994.
36) Richmond R: Educating Medical Students about Tobacco: Planning and Implementation. International Union against Tuberculosis and Lung Diseases, Southwood Press Pry Ltd., NSW, 1996.
37) Shopland DR (Ed.) : Smoking and Tobacco Control Monogr 5, Tobacco and the Clinician, NIH, Bethesda, 1994.
38) Roemer R: Ligislative action to combat the world tobacco epidemic. WHO, Geneva, 1993.
39) 総務庁, 青少年と自動販売機に関する調査研究報告書, 平成7年3月, 総務庁.
P.281 掲載の参考文献
1) Sporn MB, Dunlop NM, Newton DL, et al: Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids) . Fed. Proc. 35: 1332-1338, 1976.
4) 厚生省大臣官房統計情報部: 人口動態統計, 厚生省, 東京, 1995.
7) Lee JS, Lippman SM, Hong WK: Chemoprevention of aerodigestive tract carcinogenesis. In: Proceedings of the 7th Yousong Symposium Molecular&Cell Biology of Cancer (ed by Son K-S, Han M-H) . Yousong, Korea, 1993, pp. 106-111.
8) Hanai A, Kozono S, Fujimoto I: An estimate of cancer prevalence in Japan as of January 1, 1990. Jpn. J. Cancer Clin. 38: 419-427, 1992.
9) Wattenberg LW, Leong JL: Inhibition of the carcinogenic action of benzo (a) pyrene by flavones. Cancer Res. 30: 1922-1925, 1970.
12) Costa A, Formelli F, Chiesa F, et al: Prospects of chemoprevention of human cancers with the synthetic retinoid fenretinide. Cancer Res. 54: 2032 S-2037 S, 1994.
13) Sharma S, Stutzman JD, Kelloff GJ, et al: Screening of potential chemopreventive agents using biochemical markers of carcinogenesis. Cancer Res. 54: 5848-5855, 1994.
14) Arnold JT, Wilkinson BP, Sharma S, et al: Evaluation of chemopreventive agents in different mechanistic classes using a rat tracheal epithelial cell culture transformation assay. Cancer Res, 55: 537-543, 1995.
15) Pezzuto JM: Bioassay-guided discovery of natural products for use as chemopreventive agenets. In: Proceedings of the 86 th Annual Meeting of American Association for Cancer Research. Toronto, Ontario, Canada, 1995 ' 36: 705-706, 1995.
19) Yuspa SH: The pathogenesis of squamous cell cancer: lesson learned from studies of skin carcinogenesis-thirtythird G. H. A. Clowes Memorial Award lecture. Cancer Res. 54: 1178-1189, 1994.
20) Muto Y, Ninomiya M, Fujiki H: Present status of research on cancer chemoprevention in Japan. Jpn. J. Clin. Oncol. 20: 219-223, 1990.
21) Fujiki H, Suganuma M, Yoshizawa S, et al: Sarcophytol A and (-) -epigallocatechin gallate (EGCG) . nontoxic inhibitors of cancer development. In: Cancer Chemoprevention (ed by Wattenberg LW, Lipkin M, Boone CW, et al) . CRC, Boca Raton, 1992, pp. 393-405.
22) Komori A, Suganuma M, Okabe S, et al: Canventol inhibits tumor promotion in CD-1 mouse skin through inhibition of tumor necrosis factorαrelease and of protein isoprenylation. Cancer Res. 53: 3462-3464, 1993.
23) Kelloff GJ, Boone CW, Steele VE, et al: Progress in cancer chemoprevention: perspectives on agent selection and short-Term clinical intervention trials. Cancer Res. (Suppl.) 54: 2015-2024, 1994.
29) Komori A, Yatsunami J, Suganuma M, et al: Tumor necrosis factor acts as a tumor promoter in BALB/3T3 cell transformation. Cancer Res. 53: 1982-1985, 1993.
31) Yamane T, Takahashi T, Kuwata K, et al: Inhibition of/V-methyl-1V '-nitro-N-nitrosoguanidine-induced carcinogenesis by (-) -epigallocatechin gallate in rat glandular stomach. Cancer Res. 55: 2081-2084, 1995.
35) 武藤泰敏: 厚生省がん研究助成金による研究報告集. 厚生省, 東京, 1990, pp. 88-98.
37) Xu Y, Ho C-T, Arnin SG, et al: Inhibition of tobacco-specific nitrosoamine-induced lung tumorigenesis in A/J mice by green tea and its major polyphenol as antioxidantes. Cancer Res. 52: 3875-3879, 1992.
P.300 掲載の参考文献
1) Shindler R: History of gastroscopy. In: GASTROSCOPY (2 nd ed.) . hafner Publishing Company, new York, 1950, pp. 1-13.
3) 吉田茂昭, 廣田映五: 進行癌の発育経過からみた早期胃癌診断の再検討. Gastroenterol. Endosc. 22: 1450-1453, 1980.
4) 吉田茂昭, 山口 肇, 斉藤大三・他: 内視鏡の読み方-胃炎像の鑑別診断. 臨床消化器内科 12: 1785-1792, 1988.
5) 渡辺七六, 吉田茂昭, 山口 肇・他: 肉眼所見との対比からみた内視鏡診断-殊に慢性胃炎像との鑑別困難な早期胃癌について. 胃と腸 26: 39-50, 1991.
6) Morson BC, Dawson IMP: The polyp-cancer sequence. In: GASTROINTESTINAL PATHOLOGY, Blackwell Scientific Publications, London, 1972, pp. 542-547.
7) 工藤進英, 林 俊一, 三浦宏二 ・他: 平坦・陥凹型早期大腸癌の内視鏡診断と治療. 胃と腸 24: 317-329, 1989.
8) 津田純郎, 八尾恒良, 松井敏幸・他: 内視鏡, X線からみた表面型大腸腫瘍-肉眼分類の問題点-. 胃と腸 27: 935- 947, 1992.
9) 吉田 操, 室井正彦, 門馬久美子・他: 食道m, sm 癌の質的診断ならびに鑑別診断-内視鏡の立場から-. 胃と腸 25: 1059-1066, 1990.
10) 吉田茂昭, 辻 靖, 斉藤大三・他: 臨床経過からみた胃生検の問題点-陥凹性病変を中心に-. 胃と腸 25: 959- 969, 1990.
11) 吉田茂昭, 秋谷正彦, 山口 肇・他: 胃の腺腫: 私はこう取り扱う-高危険群の内視鏡像とその臨床的取り扱い. 胃と腸 22: 693-700, 1987.
12) 小沢壮治, 安藤暢敏, 池田佳史・他: 遺伝子異常からみた食道癌の臨床特性. 日気食会報 46: 115-120, 1995.
13) Boku N, Chin K, Hosokawa K, et al: Biological markers as a predictor for response and prognosis of unresecta-ble gastric cancer patients treated with 5-fluorouracil and cis-platin. Clin. Cancer Res. 4: 1469-1474, 1998.
16) 工藤進英: 5拡大電子スコープ. 早期大腸癌: 平坦・陥凹型へのアプローチ, 医学書院, 東京, 1993, pp. 70-75.
17) 山口 肇, 吉田茂昭, 小黒八七郎: 電子スコープと画像処理. 消化器内視鏡 1: 445-451, 1989.
18) 吉田茂昭, 山口 肇, 勝 健一・他: TV内視鏡-電子内視鏡による計量診断. 臨床医 21: 45-49, 1995.
19) 山口 肇, 吉田茂昭, 小黒八七郎: ステレオ電子内視鏡立体計測システム. 画像情報 22: 1323-1327, 1990.
20) 小田紀彦, 野波徹夫, 山口雅浩・他: 単眼内視鏡を用いた被写体の表面形状推定. Med. Imag. Tech. 11: 399-400, 1993.
21) 小野良祐, 別府和重, 平野裕志・他: 肺癌の内視鏡放射線療法. KARKINOS 6: 949-955, 1993.
22) 土方 淳: 超音波内視鏡検査. 放射線医学大系 特別巻4B超音波診断II, (田坂 晧, 松浦啓一, 飯尾正広他: 編) 中山書店, 東京, 1988, pp. 212-216.
23) 吉本一哉, 恩田浩明, 小川 聡・他: 超音波内視鏡による大腸癌の深達度診断. 消化器内視鏡の進歩 35: 186-190, 1989.
24) 大村卓味, 土方 淳, 水口安則・他: 胃外性圧排の内視鏡診断. 消化器内視鏡の進歩 40: 183-188, 1992.
25) 吉本一哉, 岸 秀幸, 長谷川毅・他: 大腸における粘膜下腫瘤および壁外病変の内視鏡下超音波診断能の検討. 消化器内視鏡の進歩 40: 216-220, 1992.
27) 土方 淳: 超音波内視鏡による胃癌の診断. 東邦医会誌 35: 406-422, 1989.
28) 安田健治朗, 宇野耕治, 田中聖人・他: 超音波内視鏡による早期胃癌の鑑別 内視鏡治療を目的に. 胃と腸 27: 1167-1174, 1992.
29) 木田光広, 今泉 弘, 西山和男・他: ラジアル型内視鏡用超音波プローブによる上部消化管疾患の診断. 消化器内視鏡 5: 149-156, 1993.
30) 石塚俊一郎, 掛村忠義, 片桐耕吾・他: バルーン・シースを用いた細径超音波プローブによる内視鏡的超音波断層法の 基礎的および臨床的検討. 消化器内視鏡の進歩 45: 78-82, 1994.
31) 高田洋孝, 小林博之, 掛村忠義・他: 内視鏡的超音波断層法による深達度診断に及ぼす大腸粘膜ひだの影響. 消化器内 視鏡の進歩 41: 217-220, 1992.
32) 相部 剛, 藤村 寛, 沖田 極: 胃の超音波内視鏡検査 (III) -胃癌の壁深達度, リンパ節転移-. 臨床消化器内科 5 (5) : 703-712, 1990.
33) 大島郁也: 超音波内視鏡による食道癌, 胃癌のリンパ節転移診断の研究. Gastroenterol. Endosc. 32: 1059-1069, 1990.
34) 池田昌弘, 両角敦郎, 佐野主一・他: 超音波内視鏡による肝・胆道系癌の診断. 消化器内視鏡 1: 791-799, 1989.
35) 野口隆義, 秋山哲司, 播磨健三・他: 内視鏡的超音波検査. 胆と膵 14: 121-128, 1993.
36) 野田 裕, 藤田直孝, 小林 剛・他: 超音波内視鏡による胆管癌の進展度診断. 胆と膵 15: 1029-1035, 1994.
37) 有村文男, 松元 淳, 中塩一昭・他: 超音波内視鏡による肝外胆管癌の進展度診断. Gastroenterol. Endosc. 34: 1863- 1870, 1992.
38) 遠藤正章, 森田隆幸, 羽田隆吉・他: 超音波内視鏡による胆管癌の進展度診断-深達度, 水平浸潤, 他臓器浸潤の診断能の検討. Gastroenterol. Endosc. 33: 243-256, 1991.
39) 一瀬雅典, 神津照雄, 浅野武秀・他: ラジアル型細径超音波プローブによる肝外胆管癌の進展度診断. 胃と腸 29: 795- 801, 1994.
40) 乾 和郎, 中澤三郎, 吉野純治・他: 胆管内超音波検査による胆管癌の深達度診断. 胆と膵 15: 1037-1041, 1994.
41) 安田健治朗, 宇野耕治, 田中聖人・他: 膵癌診断における超音波内視鏡-ERCPと対比して-. 消化器内視鏡 3: 863- 871, 1991.
42) 三竹正弘, 内藤靖夫, 塚本純久・他: 超音波内視鏡による膵癌の術前進展度診断. 胆と膵 12: 625-631, 1991.
43) 真口宏介, 藤井常志, 西野徳之・他: 超音波内視鏡による小膵癌診断. 消化器内視鏡 7: 1119-1124, 1995.
44) 古川 剛, 内藤靖夫, 廣岡芳樹・他: 細径超音波プローブによる新たなる展開. 消化器内視鏡 7: 1127-1134, 1995.
46) 田尻久雄, 小林正彦, 丹羽寛文: 経口的膵管内視鏡. 臨床消化器内科 10: 144-148, 1995.
47) 須賀俊博, 宮川宏之, 長川達哉・他: 経口的胆膵管鏡による膵疾患の診断. 消化器内視鏡 3: 879-884, 1991.
48) Izuishi K, Ryu M, Tajiri H, et al: Preoperative imaging for the location of intraductal pancreatic tumor and pancreatic duct using ERP-CT. Proc. World Congress Int. College Surgeon 15: 685-689, 1996.
49) 古川 剛, 内藤靖夫, 三竹正弘・他: Intravascular ultrasound catheterによる経胆管, 経膵管検査法. 日超医論文集59: 788-789, 1991.
P.314 掲載の参考文献
1) 厚生省大臣官房統計情報部編: 平成5年・人口動態統計. 1: 276-277, 1993.
2) 厚生統計情報部編: 国民衛生の動向・厚生の指標臨時増刊. 44: 433-434, 1997.
4) Ikeda S, Tsuboi E, Ono R, et al: Flexible bronchofiberscope. Jpn. J. Clin. Oncol. 1: 55-65, 1971.
9) 楠 洋子, 瀧藤伸英, 高田 実・他: 肺野孤立性陰影に対する気管支鏡検査の役割-経気管支的腫瘍生検 (TBTB) を中心に-. 気管支学 13: 92-97, 1991.
10) Shure D: Tissue procurement I Bronchoscopic techniques for lung cancer. Lung Cancer, Lippincott, Philadel-phia, 1996, pp. 471-479.
11) 日高 徹: 内視鏡画像診断支援システムの現況と問題点. 映像情報 (M) 26: 419-421, 1994.
12) 日本肺癌学会編: 肺癌取扱い規約. 改訂第4版, 金原出版, 東京, 1996, pp. 63-71.
13) 日本肺癌学会・気管支鏡所見分類委員会: 「肺癌取扱い規約」の一部改定 (案) について. 肺癌 36: 339-340, 1996.
14) 加藤治文, 小野寿太郎, 新妻雅行・他: 新しい吸引針による経気管支ファイバースコープ生検. 日胸疾患会誌 16: 774- 780, 1978.
19) Wang KP, Terry PB, Marsh BR: Bronchoscopic needle aspiration biopsy of paratracheal tumors. Am. Rev. Respir. Dis. 118: 17-21, 1978.
20) Schrek R, Baker LA, Ballard GP, et al: Tabacco smoking as etiologic factor in disease. Cancer Res. 10: 49-58, 1950.
21) Mills CA, Porter MM: Tabacco smoking habits and cancer of mouth and respiratory system. Cancer Res. 10: 539-542, 1950.
29) 楠 洋子, 梁 尚志, 高田 実・他: 特集「PDTの臨床」 肺癌に対するPDT. 日本レーザー医学会誌 15: 13-19, 1994.
31) Fukutomi H, Kawakita I, Nakahara A, et al: Endoscopic diagnosis and treatment of gastric cancer by laser beam. Laser-Tokyo ' 81, Laser Endoscopy (II) , Tokyo 1981, pp. 26-29.
32) 川北 勲, 中原 朗, 祭 承喜・他: レーザー光の胃癌診断への応用-レーザー光励起蛍光観察-. Prog. Dig. Endosc. 20: 57-61, 1982.
37) 加藤治文, 小中千守, 小野寿太郎・他: ヘマトポルフィリン誘導体, およびクリプトン・レーザー光線照射による犬肺癌の腫瘍局在の診断. 肺癌 21: 439-445, 1981.
41) 加藤治文, 会沢勝夫, 西宮克明・他: エキシマ・レーザーを用いた癌画像診断装置. 癌と化学療法 13: 1647-1652, 1986.
46) 古谷鉄夫, 池田徳彦, 岡田真也・他: 特集「Photodynamic diagnosis, PDT」気管支組織における自家蛍光. 日本レーザー医学会誌 17: 75-80, 1996.
48) 金 慶一, 池田徳彦, 奥中哲弥・他: 特集「Photodynamic diagnosis, PDT」気管支組織における自家蛍光. 日本レーザー医学会誌17: 81-85, 1996.
50) Douglas MC, Rodney AW: Transluminal ultrasound imaging development and devices. Intravascular Ultrasound Imaging, Raven Press, New York, 1993, pp. 31-44.
52) Ono R, Suemasu K, Matsunaka T: Bronchoscopic ultrasonography in the diagnosis of lung cancer. Jpn J. Clin. Oncol. 23: 34-40, 1993.
55) 栗本典昭, 村山正毅, 小浜祥均・他: 気管, 気管支周囲病変に対する気管支腔内超音波検査の臨床応用. 臨床放射線 42: 143-150, 1997.
56) 廣岡健児: 細径高周波超音波プローブの現況と発展. 映像情報 (M) 29: 590-593, 1997.
57) 栗本典昭, 村山正毅, 別府 敬・他: 気管支扁平上皮癌の深達度診断に対する, 気管支腔内超音波検査の経験-臨床例と針刺し実験-. 呼吸 15: 561-567, 1996.
60) 厚生省末舛班: 澤村献児, 李 龍彦, 末舛恵一・他: R2-3縦隔郭清を施行したN2肺癌切除成績の検討. 肺癌 28: 1-9, 1988.
62) Harrow EM, Wang KP: The staging of lung cancer by bronchoscopic transbronchial needle aspiration. Thorac. Endosc. 6: 223-235, 1996.
64) Faling LJ, Pugatch RD, Jung-Legg Y, et al: Computed tomographic scanning of the mediastinum in the staging of bronchogenic carcinoma. Am. Rev. Respir. Dis. 124: 690-695, 1981.
66) 三谷惟章, 下高原哲郎, 山王邦博・他: 肺癌の縦隔リンパ節転移に対するCT診断-領域別廓清リンパ節とCT所見との対比検討-. 肺癌 26: 643-649, 1986.
72) 安光 勉, 大嶋仙哉, 中野 昇・他: 手術適応が考えられた肺癌症例に対する連続600例の縦隔鏡検査成績. 肺がん集学的治療の最前線. 癌と化学療法社, 東京, 1989, pp. 10-15.
73) 曽我浩之, 竹内龍三, 栗田 啓・他: 経食道的超音波検査: 肺癌の縦隔リンパ節転移診断-特に気管分岐部リンパ節について-. 臨床外科 42: 1405-1410, 1987.
76) 加藤治文, 河手典彦, 松島 康・他: 肺針穿刺生検. 臨床病理 41: 95-109, 1980.
81) Wang KP, Terry PB, Marsh BR: Bronchoscopic needle aspiration biopsy of paratracheal tumors. Am. Rev. Respir. Dis. 118: 17-21, 1978.
84) 楠 洋子, 福岡正博: 経気管支穿刺吸引法, 縦隔鏡検査の有用性と限界. Medicina 28: 426-428, 1991.
85) 石井正憲, 小中千守, 加藤治文: 原発性肺癌における経気管支針吸引細胞診 (Transbronchial aspiration cytology: TBAC) による縦隔リンパ節及び肺門リンパ節転移の術前質的診断の検討. 気管支学 15: 627-635, 1993.
86) Schenk DA, Bower JH, Bryan CL, et al: Transbronchial needle aspiration staging of bronchogenic carcinoma. Am. Rev. Respir. Dis. 134: 146-148, 1986.
91) Osterlind K, Ihde D, Ettinger DS, et al: Staging and prognostic factors in small cell carcinoma of the lung. Cancer Treat. Rep. 67: 3-9, 1983.
93) 村上 功, 檜山桂子, 奥崎 健・他: 経気管支鏡的採取標本における肺癌遺伝子異常の解析. 気管支学 17: 691-694, 1995.
95) Sundaresan V, Ganly P, Hasleton P, et al: p53 and chromosome 3 abnormalities, characteristic of malignant lung tumours, are detectable in preinvasive lesions of the bronchus. Oncogene 7: 1989-1997, 1992.
96) 小宮武文, 平島智徳, 楠 洋子・他: 内視鏡的早期肺癌におけるp53遺伝子異常の検索. Jpn. J. Cancer. Res. 87 (suppl.) : 118, 1996.
98) Thiberville L, Payne P, Vielkinds J, et al: Evidence of cumulative gene losses with progression of premalignantepithelial lesions to carcinoma of the bronchus. Cancer Res. 55: 5133-5139, 1995.
99) Szabo E, Birrer MJ, Mulshine JL: Early detection of lung cancer. Semin. Oncol. 20: 374-382, 1993.
P.329 掲載の参考文献
2) 大松広伸, 柿沼龍太郎, 森山紀之・他: 癌検診の最前線. 癌治療, 今日と昨日 17 (3) : 25-28, 1995.
3) 柿沼龍太郎, 大松広伸, 金子昌弘・他: 末梢性微小肺がんをどう診断するか, 日本胸部臨床 56 (7) : 547-553, 1997.
5) 村上康二, 縄野 繁, 森山紀之・他: 膵充実性腫瘍の画像診断. 消化器外科 20: 1800-1809, 1997,
P.339 掲載の参考文献
3) Hirai H, Nishi S, Watabe H, et al: Some chemical, experimental and clinical investigations on α-fetoprotein. In: Alpha-fetoprotein and hepatoma (eds. by Hirai H, Miyaji T) : Gann Monogr. 14: 19-34, 1973.
4) Tang Z: Screening and early treatment of primary liver cancer with special reference to the east part of China. Ann. Med. Singapore 9: 3-5, 1989.
11) Kagan AR, Steckel RJ: Imaging cancer of unknown primary site. In: Cancer Medicine, 4th ed. (eds. by Holland JF, Bast Jr RC, Morton DL, et al) , Williams & Wilkins, Baltimore 1997, pp. 563-565.
14) Toner GC, Geller NC, Tan C, et al: Serum tumor marker half-life during chemotherapy aUows early prediction of complete response and survival in nonseminomatous germ cell tumors. Cancer Res. 50: 5904-5910, 1990.
16) 飯野四郎, 遠藤康夫: α-フェトプロテイン (AFP) . 日本臨牀 53: 696-698, 1995.
18) Ruther U, Luthgens M, Bader H, et al: Human chorionic gonadotropin in patients with pure seminoma. J. Tumor Marker Oncol. 4: 77-88, 1989.
19) Tabernero JM, Germa JR, Mora J, et al: Alpha-fetoprotein-concanavalin A binding as a maiker to discriminate between germ cell tumors and liver diseases. Proc. Am. Soc. Clin. Oncol. 14: 81, 1995.
21) Belanger L, Belanger M, Prive L, et al: Tyrosinemic hereditaire et alpha-1-fetoproteine: 1. interest clinique del 'alpha-fetoproteine dans la tyrosinemic hereditaire. Pathol. Biol. 21: 449-455, 1973.
22) 古川みどり, 中西敏己, 奥田博明・他: 肝細胞癌におけるPIUKA-IIのvitamin K 感受性に関する検討. 日消誌 85: 2583-2589, 1988.
24) Ruther U, Lathgens M, Bader H, et al: Human chorionic gonadotropin in patients with pure seminoma. J. Tumor Marker Oncol. 4: 77-88, 1989.
25) Saller B, Clara R, Spottl G, et al: Testicular cancer secretes intact human choriogonadotropin (hCG) and its freeβ-subunit: evidence that hCG (+hCG-β) assays are the most reliable in diagnosing and follow-up. Clin. Chem. 362: 234-239, 1990.
26) Bosl GJ, Geller NL, Cirrincione C, et al: Multivariate analysis of prognostic variables in patients with metastatic testicular cancer. Cancer Res. 43: 3403-3407, 1983.
27) Nisselbaum JS, Bosl GJ, Golbey D, et al: Changes in serum alpha-fetoprotein and chorionic gonadotropin in response to cancer therapy. Ann. Clin. Lab. Sci. 14: 178-188, 1984.
29) Toner GC, Geller NL, Tan C, et al: Serum tumor marker half-life during chemotherapy allows early prediction of complete response and survival in nonseminomatous germ cell tumors. Cancer Res. 50: 5904-5910, 1990.
30) Nishimura R, Ide K, Utsunomiya T, et al: Fragmentation of the β-subunit of human chorionic gonadotropin produced by choriocarcinoma. Endocrinology 123: 420-425, 1988.
31) Schutter EM, Mulder C, van Kamp GJ, et al: The beta-core fragment of human chorionic gonadotropin: biochemical background and clinical application. Anticancer Res. 17: 1255-1272, 1997.
33) Davis HW, Zurawski VR, Bast RC, et al: Characterization of the CA 125 antigen associated with epithelial ovarian carcinomas. Cancer Res. 46: 6143, 1986.
36) 有吉 寛, 桑原正喜, 葛谷和夫: CA125. 日本臨牀 53 (増刊号) : 706-709, 1995.
37) McIntire KR, Waldmann TA, Moertel CG, et al: Serum alpha-fetoprotein in patients with neoplasms of the gastrointestinal tract. Cancer Res. 35: 991-996, 1975.
46) Hass GM, Bolling TJ, Kinders JR, et al: Preparation of synthetic polypeptide domains of carcinoembryonic antigen and their use in epitope mapping. Cancer Res. 5111876-1882, 1991.
50) Magnani JL, Steplewski Z, Koprowski H, et al: Identification of the gastro-intestinal and pancreatic cancerassociated antigen detected by monoclonal antibody 19-9 in the sera of patients as a mucin. Cancer Res. 43: 5489-5492, 1983.
53) 小田桐恵美: CA 19-9. 日本臨牀 53 (増刊号) : 719-722, 1995.
55) 広田正毅, 福島喜代康, 平谷一人・他: 嚢胞性線維症とびまん性汎細気管支炎の血清中CA 19-9. 医学のあゆみ143: 789-790, 1987.
63) Hayes DF, Kiang DT, Korzun A, et al: CA l5-3 and CEA spikes during chemotherapy for metastatic breast cancer. Proc. Am. Soc. Clin. Oncol. 7: 38a, 1988.
71) Ariyoshi Y, Kato K, Sugiura T, et al: Therapeutic significance of neuron-specific enolase (NSE) in lung cancer. Proc. Am. Soc. Clin. Oncol. 5: 23, 1986.
74) 河原正明, 古瀬清行, 荒井六郎・他: 小細胞肺癌患者における血清Neuron-specific Enolase測定の意義-Carcinoem- bryonic antigenとの対比-. 癌と化学療法 14: 146-151, 1987.
75) Shaw E, Klee G, Grill J, et al: Utility of the serum tumor marker neuron specific enolase (NSE) in small cell lung cancer (SCLC) . Proc. Am. Soc. Clin. Onco1. 14: 81, 1995.
77) Miyake Y, Kodama T, Yamaguchi K: Pro-gastrin-releasing peptide (31-98) is a specific tumor marker inpatients with small cell lung carcinoma. Cancer Res. 54: 2136-2140, 1994.
78) 児玉哲郎, 阿部庄作, 山口健・他: ELISA法による血清ProGRP測定の臨床的意義. 医学と薬学 32: 87-97, 1994.
80) Kato H, Morioka H, Aramaki S, et al: Radioimmunoassay for tumor antigen of human cervical squamous cellcarcinoma. Cell Mol. Biol. 25: 51-56, 1979.
85) 沼 文隆・他: 血中SCC抗原値が異常高値を示した乾癬患者の1例. 日癌治療会誌 28: 84-89, 1993.
87) 松原義人, 安田雄司, 塙健・他: 肺癌におけるSCC抗原. 日癌治療会誌 21: 1036-1048, 1986.
94) Wollenberg B, Jan V, Schmit UM, et al: Cyfra 21-1 is not superior to SCC antigen and CEA in head and neck squamous cell cancer. Anticancer Res. 16: 3117-3124, 1996.
97) Wang MC, Valenzuela LA, Murphy GP, et al: Purification of a human prostate specific antigen. Invest. Urol. 17: 159-163, 1979.
98) Hara M, Inoue T, Koyanagi Y, et al: Immunoelectrophoretic studies of the protein component in human seminal plasma (especially its specific component) . (Forensic immunological study of body fluid and secretions. VI) Jpn. J. Legal Med. 23: 117-122, 1969.
115) Posner JB: Leptomeningeal metastases. In: Neurologic complications of cancer. F. A. Davis Company, Philadelphia, 1995, pp. 143-171.
116) Dhillon DP, Spiro SG: Malignant pleural effusions. Br. J. Hosp. Med. 29: 506, 1983.
120) Ismail MA, Rotmensch J, Mercer LJ, et al: CA-125 in peritoneal fluid from patients with nonmalignant gynecologic disorders. J. Reprod. Med. 39: 510-OOO, 1994.
122) Schwartz MK: Cancer markers (eds. by DeVita VT, Hollman S, Rosenberg SA) , 3rd ed., Lippincott Co, Philadelphia, 1993, pp. 531-542.
P.352 掲載の参考文献
1) 向井 清: 組織学的悪性度診断. 病理と臨床 7: 844-847, 1991.
2) 菅野晴夫: がんの組織病理学. がんの科学. I. がんの生物学 (太田邦夫, 山本 正, 杉村 隆・他編) 南江堂, 東京, 1980, pp. 16-42.
3) Minna JD, Pass H, Glatstein E, et al: Cancer of the lung. In Cancer. Principles & Practice of Oncology. (edited by Devita VT Jr, Hellman S, Rosenberg A) , 4th Ed, Lippincott, Philadelphia, 1989, pp. 591-705.
5) 向井 清: 増殖細胞抗原. 病理と臨床 8 (臨時増刊) : 178-185, 1990.
6) Enzinger FM, Weiss SW: Soft Tissue Tumors. 3 rd Ed. Mosby, St. Louis, 1995, pp. 1-16.
8) 下山正徳, 向井 清, 菊池昌弘・他: 専門病理医による非ポジキンリンパ腫の病理診断とホルマリン固定標本による TBマーカー免疫診断の一致率: LCPP (Lymphoma Clinico-pathology Panel) による共同研究. がんの臨床 39: 739 -765, 1993.
9) Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 4th Ed, WB Saunders, Philadelphia, 1989, pp. 239-305.
10) Seidman JD, Berman JJ: Premalignant nonepithelial lesions: Abiological classification. Mod. Pathol. 6: 544- 554, 1993.
11) 向井 清: 腫瘍の病理診断に用いられる免疫組織化学マーカー. 癌と化学療法 18: 1383-1388, 1991.
12) 町並陸生: 電子顕微鏡所見を病理組織診断にどう役立てるか. 病理と臨床 10 (臨時増刊) : 8-15, 1992
14) 加藤治文, 小中千守, 平野 隆・他: CAS 200システムを用いた予後因子の検討. 病理と臨床 12: 853-857, 1994.
15) Asamura H, Nakajima T, Mukai K, et al: Degree of malignancy in thymic epithelial tumors in terms of nuclear DNA content and nuclear area. Am. J. Pathol. 133: 615-622, 1988.
P.357 掲載の参考文献
9) 覚道健一, 中村靖司, 長沼 広・他: 特集-甲状腺癌オブザーバー・バリエーション. 病理と臨床 14: 580-582, 1996.
10) Mukai K, Abe M, Ohshima K, et al: Hodgkin 's disease: results of central pathology review for a protocol study (JGOG 890 G) in Japan. Mod. Pathol. 10: 130 A, 1997.
P.371 掲載の参考文献
1) Wilson JMG, Jungner G: Principles and Practice of Screening for Diseases. WHO, Geneva, 1968 (重松逸造, 福島一郎, 加藤孝之 (監訳) : 疾病スクリーニングの原理と方法. 日本公衆衛生協会, 東京, 1970, pp. 1-4) .
2) Cole P, Morrison AS: Basic issues in population screening for cancer. J. Nat1. Cancer Inst. 64: 1263-1272, 1980.
3) Miller AB: Principles of screening and the evaluation of screening programs. In: Screening for Cancer (ed by Miller AB) , Academic Press, Orlando, 1985, pp. 3-24.
4) Prorok PC, Miller AB (eds) : Screening for Cancer. UICC Technical Report Series Volume 78, UICC, Geneva, 1984, p. 4.
5) Greenwald P, Costlow R, Prorok P, et al: Screening in the context of cancer control. In: Screening for Cancer (ed by Miller AB) , Academic Press, Orlando, 1985, pp. 25-48.
6) 大島 明: 癌集団検診の評価手法の基本. 日医師会誌 107: 527-530, 1992.
12) Shapiro S, Venet W, Strax P, et al: Periodic Screening for Breast Cancer: The Health Insurance Plan Project and Its Sequelae. The Johns Hopkins Univ. Press, Baltimore, 1988.
14) Prorok PC: Screening studies. In: Cancer Prevention and Control (eds by Greenwald P, Kramer BS, Weed DL) , Marcel Dekker, New York, 1995, pp. 225-242.
20) 阿部陽介, 光島 徹, 永谷京平・他: Case-control studyの手法を用いた胃癌死亡減少に対する胃集団検診の効果の疫学的評価. 日消病会誌 92: 836-845, 1995.
23) 久道 茂 (編) : 厚生省がん研究助成金による適正な大腸集団検診制度の確立と精度の向上に関する研究. 平成2年度 報告書, 東北大学医学部公衆衛生学教室, 仙台, 1991, p. 11.
26) Hakama M, Miller AB, Day NE: Screening for Cancer of the Uterine Cervix. IARC Scientific Publication No. 76, IARC, Lyon, 1986.
27) U. S. Preventive Services Task Force: Guide to Clinical Preventive Services, 2nd ed., Williams & Wilkins, Baltimore, 1996, pp. 105-117.
30) Chamberlain J, Miller AB (eds) : Screening for Gastrointestinal Cancer. Hans Huber Publishers, Toronto, 1988, p. 63.
33) Ajiki W, Tsukuma H, Oshima A, et al: Effects of mass screening on incidence, mortality, and survival rates inOsaka, Japan. Cancer Causes and Control 1998 (in press) .
34) 厚生省統計情報部: 平成7年度老人保健事業報告, 厚生省統計情報部, 東京, 1997.
P.379 掲載の参考文献
4) Fortner JG: Regional resection of cancer of the pancreas. Surgery 73: 307-320, 1973.
9) Sobin LH, Wittekind CH: TNM Classification of Malignant Tumours (Fifth Edition) , Wiley-Liss, New York, 1997, pp. 1-4.
10) Annual report of national cancer center hospital 1996. National cancer center hospital, Tokyo, 1996, pp. 34-57.
11) がんの統計編集委員会 (委員長: 垣添忠生) 編: がんの統計 '97. 財団法人がん研究振興財団, 東京, 1997.
17) 後藤満一, 門田守人, 左近賢人・他: 膵癌における術中照射療法の評価. 日外会誌 94: 269-276, 1993.
24) 川原英之, 藤田博正, 小田桐重遠・他: 大動脈合併切除を伴う食道癌切除例の1例. 日外会誌 86: 1546-1551, 1985.
27) 広野達彦, 小池輝明, 滝沢恒世・他: 胸骨正中切開による両側縦隔リンパ節郭清とその意義. カレントテラピー 4: 1480-1483, 1986.
28) 大橋一郎, 高木国夫, 小西敏郎・他: 胃癌の大動脈リンパ節転移陽性の5年生存例について. 日消外会誌 9: 112-116, 1976.
29) 佐々木壽英, 梨本 篤, 筒井光広・他: 胃癌大動脈周囲リンパ節郭清の適応. 日消外会誌 22: 1749-1754, 1989.
31) 米村 豊, 藤村 隆, 伏田幸夫・他: 腹膜播種性胃癌に対するsubtotal peritonectomy+温熱化学療法. 手術 49: 553-557, 1995.
35) 山本順司, 小菅智男, 島田和明・他: 転移性肝癌の外科治療; 適応と治療成績. 消化器外科 18: 1655-1662, 1995.
36) 幕内博康, 町村貴郎, 杉原 隆・他: 食道粘膜癌の内視鏡的診断と治療. 消化器内視鏡 2: 447-452, 1990.
37) 平尾雅紀, 小林多加志, 長谷良高男・他: 胃の腫瘍性病変に対する内視鏡的切除法. Gastroenterol. Endosc. 25: 1942- 1953, 1983.
39) 金平永二 , 大村健二 , 渡辺洋宇: 特殊な直腸鏡を用いた直腸腫瘍の治療. 手術 48: 1465, 1994.
40) 三富利夫, 幕内博康: 早期食道癌に対する内視鏡的粘膜切除術. 消化器外科 19: 563-570, 1996.
41) 竹腰隆男, 藤井 彰, 馬場保昌・他: 早期胃癌に対する内視鏡切除の限界; 長期予後からみた限界と対策. 臨牀消化器 内科 8: 649-660, 1993.
43) 大橋秀一: 腹腔鏡下胃内手術. 手術 48: 333-337, 1994.
44) 大上正祐, 熊井浩一郎, 若林 剛・他: 早期胃癌に対する新しい治療法; lesion lifting法による腹腔鏡下胃局所切除術. 胃と腸 28: 1461-1468, 1993.
45) Gagner M, Rheault M, Dubuc J: Laparoscopic partial hepatectomy for liver tumor. Surg. Endosc. 6: 97, 1992.
46) Jacob M, Verdeja JC, Goldstein HS: Minimally invasive colon resection (laparoscopic colectomy) . Surg. Laparosc. Endosc. 1: 144-150, 1991.
50) 小西文雄, 永井秀雄, 岡田真樹・他: 大腸癌に対する腹腔鏡下手術のcontroversy; 現時点で進行癌は適応となりうるか? JSES 1: 19, 1996.
53) 秋山 洋, 佐藤靖雄, 高橋文夫・他: 非開胸食道全摘出による一期的咽頭胃吻合術. 手術 27: 1-5, 1973.
54) 中野博重, 渡辺明彦, 澤田秀智・他: 胃癌に対する幽門保存胃切除術の適応と成績. 外科治療 68: 131-135, 1993.
55) Traverso LW, Longmire WP: Preservation of the pylorus in pancreaticoduodenectomy. Surg. Gynecol. Obstet. 146: 959-962, 1978.
59) 市田文弘, 谷川久一: 肝移植適応規準. 国際図書出版, 東京, 1991, pp. 38-41.
62) Satava RM: Lest we forget the future. J Am. Coll. Surg. 184: 519-520, 1997.
P.399 掲載の参考文献
1) Hall EJ: Radiology for the radiologist, Fourth ed, Lippincott, Philadelphia, 1994.
4) Phillips TL: Radiation-chemotherapy interaction. Lung Cancer (eds by Pass HI, et al) , Lippincott-Raven, New York, 1995, pp. 251-270.
6) Fowler JF: What next in fractionated radiotherapy? Br. J. Cancer 49 (S) : 285-300, 1984.
15) Saunders MI, Dische S, Barrett A, et al: Randomized multicentre trials of CHART vs conventional radiotherapy in head and neck and non-small℃ell lung cancer: an interium report. Br. J. Cancer 73: 1455-462, 1996.
35) Soresi E, Clerici M, Grilli R, et al: Arandomized clinical trial comparing radiation therapy v radiation therapy plus cis-Dichlorodiammine plainum (II) in the treatment of locally advanced non-srnall cell lung cancer. Semin. Oncol. 15: 20-25, 1988.
37) Furuse K, Fukuoka M, Takada Y, et al: Arandomized phase III study of concurrent versus sequential thoracic radiotherapy (TRT) in combination with mitomycin C (M) , vindesine (V) , and cisplatin (P) in unresectable stage III non-small cell lung cancer (NSCLC) : Preliminary analysis. ASCO proceedings: 459 a, 1997.
54) Launois B, Delarue D, Campion JP, et al: Preoperative radiotherapy for carcinoma of the esophagus. Surg. Gynecol. Obstet. 153: 690-692, 1981.
60) Stearns MW, Deddish MR, Quan SHQ, et al: Preoperative roentgen therapy for cancer of the rectum and rectosigmoid. Surg. Gynecol. Obstet. 138: 584-586, 1974.
66) Fok M, Sham JST, Choy D, et al: Postoperative radiotherapy for carcinoma of the esophagus: aprospective, randomized controlled study. Surgery 113: 138-147, 1993.
67) Teniere P, Hay J-M, Fingerhut A, et al: Postoperative radiation therapy dose not increase survival after resection for squamous cell carcinoma of the middle and lower esophagus as shown by a multicenter controlled trial. Surg. Gynecol. Obstet. 173: 123-130, 1991.
84) Egawa S, Tsukiyama I, Watanabe S, et al: Arandomized clinical trial of hyperthermia and radiation versus radiation alone for superficially located cancers. J. Jpn. Soc. Ther. Radiol. Oncol. 1: 135-140, 1989.
P.420 掲載の参考文献
6) Wiechel KL: Percutaneous transhepatic cholangiogrophy: technique and application. Acta Chir. Scand. (SuppL) 330: 1, 1964.
8) Adam A, Hemingway AP: Interventional radiology. In: Oxford Textbook of Palliative Medicine (2 nd edition) (eds. by Doyle D, Hanks GWC, MacDonald N) . Oxford University Press, Oxford, New York, Tokyo, 1998, pp. 239-248.
14) 田口鐵男, 斎藤達雄, 太田 潤・他: YM 881 (ジノスタチンスチマラマー) 懸濁液の肝動注における第II相試験. 癌と化学療法 18: 1665-1675, 1991.
18) 第9回全国原発性肝癌追跡調査報告 (1986-1987) , 日本肝癌研究会, 1990.
19) 西村幸洋, 打田日出夫, 郭 啓勇・他: 肝細胞1075例に対する肝動脈塞栓術-特に累積生存率と3年以上生存9例からみた抗癌剤混入リピオドール併用の評価-. 日癌治療会誌 26: 2279-2289, 1991.
22) 高田恵二: 原発性肝癌に対する経カテーテル治療の適応と選択に関する研究. 肝臓 35: 496-508, 1992
23) 畑中義美, 山下康行, 荒川昭彦・他: 1. 進行肝細胞癌に対するIVR (2) 切除不能肝細胞癌の肝動脈塞栓療法における予後因子. IVR 10: 253-256, 1995.
25) 高安幸生, 小竹正昌, 楢崎勝弘・他: 1. 進行肝細胞癌に対するIVR (4) リザーバーによる動注化学療法. IVR 10: 263-267, 1995.
35) Meta-Analysis Group in Cancer: Reappraisal of hepatic arterial infusion in the treatment of nonresectable liver metastases from colorectal cancer. J. NatL Cancer Inst. 881252-258, 1996.
36) 荒井保明: IVRにおける肝動注化学療法の基本手技. 臨床放射線 12: 1497-1508, 1993.
37) Arai Y, Inaba Y, Takeuchi Y: Interventional techniques for hepatic infusion chemotherapy. In: Interventional Radiology (Third Edition) (ed. by Casterfieda-Zuniga WD) . Williams & Wilkins, Baltimore, Philadelphia, London, Paris, Bangkok, Buenos Aires, Hong Kong, Munich, Sydney, Tokyo, Wroclaw, 1997, pp. 192-206.
39) 荒井保明: II. 転移性肝癌に対する動注化学療法3. 血流改変術. IVR 8: 42-46, 1993.
40) 荒井保明, 木戸長一郎, 有吉 寛: 大腸癌肝転移の治療-間歇的大量5FU肝動注化学療法. カレントテラピー 12: 94-99, 1994.
43) 荒井保明, 富田和美, 大橋計彦・他: 動注化学療法とQOL. 癌治療と宿主 6: 267-272, 1994.
44) 荒井保明: 大腸癌肝転移に対する動注化学療法の現況と研究戦略. 癌と化学療法 20: 2467-2471, 1993.
46) 荒井保明, 澤田 敏, 中島康雄・他: Non-vascular IVR-画像診断手技の治療への応用- (木戸長一郎監) , 癌と化学療法社, 東京, 1991, pp. 143-151.
47) 蘆田 浩: IV 膿瘍ドレナージ. 放射線医学大系 特別巻 1 インターベンショナルラジオロジー (編集代表 田坂晧) , 中山書店, 東京, 1986, pp. 288-299.
48) 荒井保明: 8-26 Interventional radiologyの手技を用いた治療法の有効性についての研究. 厚生省がん研究助成金による研究報告書 平成8年度, 国立がんセンター, 東京, 1996, pp. 422-426.
53) 前田宗宏, 玉田俊明, 幕谷士郎・他: 消化管のステント. 画像診断 13: 309-314, 1993.
56) 澤田 敏: ステントの機能とその適応. 映像情報 (M) 27: 1159-1163, 1995.
57) 岸 和史, 光実 淳, 園村哲朗・他: 門脈腫瘍栓に対するstent治療法の開発-dacron sheet covered self expandable metallic stentによる経皮経肝門脈形成術-. 日医放会誌 52: 1192-1194, 1992.
58) 荒井保明: 6-30 Interventional Radiologyの手技を用いた治療法の有効性に関する研究. 厚生省がん研究助成金による研究報告集 平成7年度, 国立がんセンター, 東京, 1995, pp. 242-247.
62) Uchida H, Yoshioka T, Maeda M, et al: Use of original, modified, and spiral Z stents in the biliary system.
63) Stents-state of the art and future development (ed. by Liermann DD) . Polyscience Publication lnc, 1995, pp. 202-207.
64) 齋藤博哉, 桜井康雄, 高 明夫・他: メタリックステントによる悪性胆道狭窄の治療. 胆と膵 16: 931-938, 1995.
65) Cwikiel W: Esophageal nitinol stents: long-term results-state of the art and future development. (ed. by Liermann DD) . Polyscience Publication Inc, 1995, pp. 218-221.
68) 藤原義夫, 澤田 敏, 田辺芳雄・他: Metallic stentの気管, 食道, 尿道への応用-動物実験を中心として-. 臨床放射線 35: 557-562, 1990.
69) 青木貴徳, 齋藤博哉, 高 明夫・他: 悪性食道気管支瘻に対するGore-Tex covered expandable metallic stentによる治療. Gastroenterol. Endosc. 37: 827-832, 1995.
70) 冨田 優, 廣田省三, 松本真一・他: 連結部を持たない両面被覆covered stentの検討. IVR 10: 381-384, 1995.
73) 荒井保明: 8-26 Interventional radiologyの手技を用いた治療法の有効性についての研究. 厚生省がん研究助成金による研究報告書 平成9年度. 国立がんセンター, 東京, 1996. (印刷中)
74) 栗林幸夫, 大滝 誠, 岩田美郎・他: 消化管出血. 画像診断 11 (別冊) : 111-125, 1992.
76) 関 竜夫, 白土桃子: 消化管出血に対するIVR (2) 腫瘍性出血. IVR 10: 18, 1995.
77) 石川 徹: Interventional radiologyの歴史と展望. Non-vascular Interventional Radiology 手技と考え方 (石川徹編) , 中外医学社, 東京, 1993, pp. 1-8.
79) 中島康雄: 3. 胸部 I. 生検 1. 経皮的穿刺-A. 肺. Non-vascular Interventional Radiology 手技と考え方 (石川徹編) , 中外医学社, 東京, 1993, pp. 17-23.
80) 荒井保明: 3. 胸部 I. 生検 1. 乳房および胸壁. Non-vascular Interventional Radiology 手技と考え方 (石川徹編) , 中外医学社, 東京, 1993, pp. 44-48.
81) 林 信成: 4. 腹部 I. 生検 1. 腫瘤. Non-vascular Interventional Radiology 手技と考え方 (石川徹編) , 中外医学社, 東京, 1993, pp. 72-79.
82) 荒井保明: 6-30 Interventional Radiologyの手技を用いた治療法の有効性に関する研究. 厚生省がん研究助成金による研究報告集 平成6年度, 国立がんセンター, 東京, 1994, pp. 459-463.
85) Dedrick CG, Olson RR, Athanasoulis CA: Transcatheter embolization of the spleen. In: Interventional Radiology (eds. by Athanasoulis CA, Pfister RC, Greene RE, Roberson GH) . WB. Saunders, Philadelphia, 1982, pp. 223-227.
88) 吉川公彦, 打田日出夫, 坂口 浩・他: TIPS最新レヴュー;門脈圧亢進症, 食道・胃静脈瘤治療におけるTIPSの位置付け. 日医放会誌 54: 22-24, 1994.
P.453 掲載の参考文献
2) De Vita VT Jr: Principles of chemotherapy. In: Cancer: Principles and Practice of Oncology (eds. by De Vita VTJr, Hellman S, Rosenberg SA) . 4th Edition, J B, Lippincott Co., Philadelphia, 1993, pp. 276-292.
3) 西條長宏: 癌化学療法の変貌. Current review: 癌化学療法93-94 (鶴尾 隆, 西條長宏編) , 中外医学社, 東京, 1993, pp. 4-10.
4) 西條長宏: 進歩する化学療法. 図説臨床「癌」シリーズ癌化学療法の進歩 (末舛恵一, 西條長宏編) (新版) , メジカルビュー社, 東京, 1993, pp. 6-11.
5) 西條長宏: 癌の分子治療の展開. (西條長宏編) , 医薬ジャーナル社, 大阪, 1995, pp. 9-28.
6) 石田智之, 西條長宏: 抗癌剤における薬物動態および薬剤耐性の最新情報. 先端医療 12: 77-79, 1995.
7) 石田智之, 西條長宏: 新しい抗癌剤の動向. 医学と薬学 32: 407-414, 1994.
8) 有岡 仁, 西條長宏: Biochemical modulationの考え方. 癌治療とbiomodulation (漆崎一朗編) . 医薬ジャーナル社, 大阪, 1995, pp. 93-118.
9) 赤沢修吾, 大和朋子: Biomodulation. Oncology Frontier (太田和雄, 塚越 茂, 西條長宏・編) . 先端医学社, 東京, 1996, pp. 40-47.
12) WHO Handbook for reporting results of cancer treatment. WHO, Geneva, 1979.
13) Grading of toxicity: In Manual of Oncologic Therapeutics 1991/1992 (ed. by Wittes WE) , Lippincott, Philadel-phia, 1991, pp. 448-455.
18) Goldie JH, Coldman AJ: Role of mathematical modeling in protocol for mutation in cancer chemotherapy. Cancer Treat. Rep. 63: 1041-1045, 1985.
19) Nathanson L, Hall TC, Schilling AC, et al: Concurrent combination chemotherapy of human solid tumors: Experience with three-drug regimen and review of the literature. Cancer Res. 29: 419-425, 1969.
24) Freireich EJ, Karon M, Frei E: Quadruple combined chemotherapy (VAMP) for acute lymphocytic leukemia in children. Proc. Am. Assoc. Cancer Res. 5: 20, 1964.
34) Van Belle S, Bleiberg H, Canon JL, et al: Optimal combination therapy with tropisetron in 445 patients with subtotal control of chemotherapy-induced nausea and emesis. Proc. Am. Soc. Clin. Oncol. 13: 430, 1994.
35) Johnsonbaugh RE, Mason BA, Friedman CJ, et al: Oral granisetron is an effective anti-emetic in patients receiving moderatory emetogenic chemotherapy. Proc. Am. Soc. Clin. Oncol. 13: 437, 1994.
36) Rittenberg CN, Gralla RJ, Lettow LA, et al: New approaches in preventing delayed emesis: Altering the time of regimen initiation and use of combination therapy in a 109 patients trial. Proc. Am. Soc. Clin. Oncol. 14: 526, 1995.
39) De Vita VT Jr: Dose response is alive and welL J. Clin, Oncol. 4: 1157-1159, 1986.
48) Capri G, Tarengi E, Fulfago F, et al: The role of taxanes in the treatment of breast cancer. Semin. Oncol. 23: 68-75, 1996.
49) 末舛恵一, 西條長宏・編: 化学療法の進歩. 図説臨床 [癌]シリーズno. 1, メジカルビュー社, 東京, 1993, pp. 79-84.
50) 大塚貞明, 馬場秀夫, 杉町圭蔵: 感受性テスト. current review癌化学療法1993-94 (鶴尾隆, 西條長宏, 編) , 中外医学社, 東京, 1993, pp. 103-109.
51) Weisenthal LM, Marsden JA, Dill PL, et al: A novel dye exclusion method for testing in vitro chemosensitivity of human tumors. Cancer Res. 43: 749-757, 1983.
52) Funa K, Dawson N, Jewett PB, et al: Automated fluorescent analysis for drug-induced cytotoxicity assays. Cancer Treat. Rep. 70: 1147-1151, 1986.
54) 東 弘, 伊藤英太郎, 森 武貞・他: 制癌剤感受性テストの理論と実際-とくに核酸合成阻害を指標とする方法 (INSA法) について. 綜合臨床 20: 1360-1367, 1971.
55) 東 弘: 癌化学療法の問題点-制癌剤感受性試験 (INAS法の臨床経験) . 癌の臨床 25: 761-764, 1979.
56) 近藤達平: 制癌剤の適応-感受性試験. 最新医学 19: 2304-2311, 1964.
57) 市橋秀仁, 津荷龍生, 近藤達平・他: ATPを指標とする制癌剤感受性試験. 日癌治療会誌 22: 1090, 1987.
59) 楠本宏記, 前原喜彦, 杉町圭蔵: 抗癌剤感受性試験の意義と問題点-SDI法を中心として図説臨床「癌」シリーズno. 1 癌化学療法の進歩, 末舛恵一, 西條長宏・編, メジカルビュー社, 東京, 1993, pp. 79-84.
62) Tanigawa N, Kern DH, Hikasa Y, et al: Rapid assay for evaluating the chemosensitivity of human tumors in soft agar culture. Cancer Res. 42: 2159-2164, 1982.
63) Kern DH, Drogemuller CR, Kennedy MC, et al: Development of a miniaturized improved nucleic acid precursor incorporation assay for chemosensitivity testing of human solid tumor. Cancer Res. 45: 5436-5441, 1985.
69) 藤田昌英, 大嶋一徳, 薄金真雄・他: ヌードマウス移植-消化器癌および乳癌株の特徴-とくにそのCEA産生性と抗癌剤感受性について. 日外会誌 83: 457-467, 1982.
70) Bogden AE: Arapid screening method for testing chemotherapeutic agents against human tumor xenografts. Symposium on the Use of Athymic (nude) mice in Cancer Research, Gustav Fischer Inc, New York, 1978, pp. 231-250.
74) Levi FA, Blum JP, Lemaigre G, et al: Afour-day subrenal capsule assay for testing the effectiveness of anticancer drugs against human tumors. Cancer Res. 44: 2660-2667, 1984.
81) Debernardis D, Sire EG, Eeudis PD, et al: P53 status does not effect sensitivity of human ovarian cancer cell line to paclitaxel. Cancer Res. 57: 870-874, 1997.
83) Niimi S, Nakagawa K, Saijo N: Relationship between sensitivity to anticancer agents and GSH content and GST activity. Jikei Med. J. 391395-407, 1992.
85) Lu Z, Zhang R, Diasio RB: Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: Population characteristics, newly identified deficient patients and clinical implication in 5-fluorouracil chemotherapy. Cancer Res. 53: 5433-5438, 1993.
86) Niimi S, Nakagawa K, Sugimoto Y, et al: Mechanism of cross-resistance to a camptothecin analogue (CPT-11) in a human ovarian cell line selected by cisplatin. Cancer Res. 52: 328-333, 1992.
87) Sugimoto Y, Ohe Y, Nishio K, et al: In vitro enhancement of fluoropyridine-induced cytotoxicity by leucovorin in colorectal and gastric carcinoma cell lines but not in non-small cell lung carcinoma cell lines. Cancer
92) Nishio M, Nishio K, Arioka H, et al: Increase of HMG proteins in cis-DDP resistant cell lines. J. Cell Pharmacol. 1: 251-255, 1994.
97) Andoh T, Yasui Y, Koiwai O, et al: Molecular basis of resistance to CPT-11. a specific inhibitor of DNA topoisomerase I. In: The mechanism and new approach on drug resistance of cancer cells (ed. by Miyazaki T, Takaku F and Sakurada K) . Elsevier Science Publishers, Amsterdam, 1993, pp. 95-101.
100) Hamaguchi K, Godurin AK, Yakushiji M, et al: Cross resistance to diverse drugs is associated with primary cisplatin resistance in ovarian cancer cell lines. Cancer Res. 53: 5225-5232, 1993.
101) Ishikawa T: Glutathione S-conjugate export pump.: Structure and function of glutathione-S-transferase (ed. by Tew KD, Pickett CB, et al) , CRC press, Boca Raton, 1993, pp. 211-221.
102) Reed E, Parker RJ, Gill I, et al: Platinum-DNA adduct in leucocyte DNA of malignancies. Cancer Res. 53: 3694-3699, 1993.
103) Saijo N, Lazo JS: "Metallothioneins in drug resistance" in Drug Resistance in Oncolgy (ed. by Teicher BA) , Marcel Dekker, New York, 1993, pp. 339-350.
105) Zhang B, Seki S, Akiyama K, et al: Detection and analysis by gel electrophoresis of cisplatin-mediated DNA damage. Acta. Med. Okayama 46: 427-434, 1992.
107) Morikage T, Ohmori T, Nishio K, et al: Modulation of cisplatin sensitivity and accumulation by amphotericin Bin cisplatin-resistant human lung cancer cell lines. Cancer Res. 53: 3302-3307, 1993.
110) Kasahara K, Fujiwara Y, Nishio K, et al: Metallothionein content correlates with the sensitivity of human small cell lung cancer cell lines to cisplatin. Cancer Res. 51: 3237-3242, 1991.
111) Kurakawa H, Nishio K, Ishida T, et al: Effect of glutathione depletion on cisplatin resistance in cancer cells transfected with theγGCS gene. Jpn. J. Cancer Res. 88: 108-110, 1997.
115) Mirski SEL, Evans CD, Almquist KC, et al: Alterd topoisomerase IIa in a drug-resistant small cell lung cancer cell line selected in VP-16. Cancer Res. 53: 4866-4873, 1993.
116) Kanzawa F, Sugimoto Y, Minato K, et al: Establishment of a camptothecin analogue (CPT-11) -resistant cell line of human non-small cell lung cancer: characterization and mechanism of resistance. Cancer Res. 50: 5919-5924, 1990.
120) Akiyama T, Yasida T, Tsujita M, et al: GI phase accumulation induced by UCN-01 is associated with dephaphorylation of RB and cdk 2 proteins as well as induction of cak inhibitor P 21/Cip I/WAF l in P53-mediated human epidermoid carcinoma A 431 calls. Cancer Res. 57: 1495-1501, 1997.
127) Goldie JH, Coldman AJ, Gudauskas GA: Rationale for the use of alternating non-cross resistant chemotherapy. Cancer Treat. Rep. 66: 439-449, 1982.
128) Goldie JH, Coldman AJ: Amathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate. Cancer Treat. Rep. 63: 1727-1733, 1979.
129) Coldman AJ, Goldie JH: Impact of dose intensive chemotherapy on the development of permanent drug resistance. Semin. Oncol. 14 (suppl. 4) : 29-33, 1987.
130) Norton L, Simon R: Tumor size, sensitivity to therapy, and design of treatment schedules. Cancer Treat. Rep. 61: 1307-1317, 1977.
132) Hryniuk WM, Levine MN: Applications of dose intensity to problems in chemotherapy of breast and colorectal cancer. Semin. Oncol. 14 (suppl. 4) : 3-11, 1987.
135) Fukuoka M, Takada M, Masuda S, et al: Dose intensive weekly chemotherapy with or without recombinant human granulocyte colony-stimulating factor in extensive-stage small-cell lung cancer. Proc. ASCO 11: 290, 1992.
136) Furuse K, Kubota K, Nishiwaki Y, et al: For the JCOG: Phase III study of dose intensive weekly chemotherapy with rh GCSF versus standard chemotherapy in ED-SCLC. Proc. Am. Soc. Clin. Oncol. 15: 375, 1996.
138) De Vita VT Jr, Hubbard SM, Longo DL, et al: The chemotherapy of lymphomas: looking back, moving forward-the Richard and Hinda Rosental Foundation Award lecture. Cancer Res. 4715810-5824, 1987.
147) Baselga J, Tirpathy D, Mendelsohn J, et al: Phase II study of recombinant human anti-HER 2 monoclonal antibody (rhuMAb HER 2) in stage IV breast cancer (BC) : HER 2-shedding dependent pharmacokinetics and antitumor activity. Proc. ASCO l4: 103, 1995.
148) Pegram M, Lipton A, Pietras R, et al: Phase II study of intravenous recombinant humanized anti-p 185 HER 2 monoclonal antibody (rhuMAb HER 2) plus cisplatin in patients with HER-2/NEU overexpressing metastatic breast cancer. Proc. ASCO 14: 106, 1995.
149) 抗悪性腫瘍薬の臨床評価法に関するガイドライン. 新薬評価ガイドライン1991 (日本公定書協会編) , 薬事日報社, 東京, 1991.
150) GCPハンドブック. 厚生省薬務局審査第一課監修, 薬業時報社, 東京, 1990.
151) Collins JM, Zaharko DS, Dedrick RL, et al: Potential roles for preclinical pharmacology in phase I clinical trials. Cancer Treat. Rep. 70: 73-80, 1986.
159) Ames MM, Loprinzi CL, Collins JM, et al: Phase I and clinical evaluation of piroxantron hydrochloride (oxantrazole) . Cancer Res. 50: 3905-3909, 1990.
160) Hantel A, Donehower RC, Rowinsky EK, et al: Phase I study and pharmacodynamics of piroxantrone (NSC349174) , anew anthrapyrazole. Cancer Res. 50: 3284-3288, 1990.
161) Erlichman C, Moore M, Kerr IG, et al: Phase I pharmacokinetic and pharmacodynamic study of a new anthrapyrazole CI-937 (DuP 937) . Cancer Res. 51: 6317-6322, 1991.
163) Donehower R, Grove W, Whitfield L, et al: Successful use of pharmacologically guided dose escalation (PGDE) in a phase I trial of CI-958. Proc, ASCO 12: 139, 1993.
164) Levantal BG, Wittes RE: Combination chemotherapy. In: Research Methods in Clinical Oncology (eds. by Levantal BG, Wittes RE) , Raven Pres, New York, 1988, p. 129.
167) Kaufmann SH: Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: acautionary note. Cancer Res. 49: 5870-5878, 1989.
168) Eastman A: Activation of programmed cell death by anticancer agents: cisplatin as a model system. Cancer Cells 2: 275-280, 1990.
172) Fujiwara Y, Yamakido M, Fukuoka M, et al: Phase II study of irinotecan (CPT-11) and cisplatin (CDDP) in patients with small cell lung cancer (SCLC) . Proc. ASCO 13: 335, 1994.
173) 古江 尚: 塩酸イリノテカン (CPT-11) . 癌と化学療法 21: 709-717, 1994.
174) 太田和雄, 大野竜三, 白川 茂・他: 悪性リンパ腫・急性白血病に対する塩酸イリノテカン (CPT-11) の後期第II相臨床試験. 癌と化学療法 21: 1047-1055, 1994.
175) 田口鐵男, 冨永 健, 小川一誠・他: 再発・進行乳癌に対するCPT-11 (塩酸イリノテカン) の後期第II相臨床試験. 癌と化学療法 21: 1017-1024, 1994.
176) 二ツ木浩一, 涌井 昭, 中尾功・他: 再発・進行胃癌に対する塩酸イリノテカン (CPT-11) の後期第II相臨床試験. 癌と化学療法 21: 1033-1038, 1994.
177) 坂田 優, 島田安博, 吉野正曠・他: 進行膵がんに対するCPT-11 (塩酸イリノテカン) の後期第II相臨床試験. 癌と化学療法 21: 1039-1045, 1994.
183) Thigpen T, Blessing J, Ball H, et al: Phase II trial as second line therapy for ovarian carcinoma. Proc. ASCO9: 156, 1990.
184) Einzig AI, Wiernik PH, Sasloff J, et al: Phase II study of Taxol (T) in patients (Pts) with advanced ovarian cancer. Proc. AACR 31: 187, 1990.
187) Chang A, Kim K, Glick J, et al: Phase II study of taxol in patients with stage IV non-small cell lung cancer (NSCLC) . Proc. ASCO 11: 293, 1992.
188) Murphy WK, Winn RJ, Fossella FV, et al: A phase II study of taxol (NSC 125973) in patients (pts) with nonsmall cell lung cancer (NSCLC) . Proc. ASCO 11: 294, 1992.
189) Kanzawa F, Sugimoto Y, Minato K, et al: Establishment of a camptothecin analogue (CPT-11) -resistant cell line of human non-small cell lung cancer: characterization and mechanism of resistance. Cancer Res. 50: 5919-5924, 1990.
192) Ohta S, Nishio K, Ohmori T, et al: A taxol resistant human small cell lung cancer cell line is partially dependent of taxol for its growth. Proc. AACR 34: 304, 1993.
194) Ram Z, Culver KW, Walbridge S, et al: In situ retroviral-mediated gene transfer for the treatment of brain tumors in rats. Cancer Res. 53: 83-88, 1993.
196) Georges RN, Mukhopadhyay T, Zhang Y, et al: Prevention of orthotopic human lung cancer growth by intratracheal instillation of a retroviral antisense K-ras construct. Cancer Res. 53: 1743-1746, 1993.
197) Kashani-Sabet M, Funato T, Tone T, et al: Reversal of the malignant phenotype by an ant卜燃ribozyme. Antisense Res. Dev. 2: 3-15, 1992.
202) 小倉 剛: サイトカインの癌治療への応用. 免疫薬理 12: 356-359, 1994.
206) 高上洋一: 白血病に対する末梢血幹細胞移植. 今日の移植 4: 72-79, 1991.
207) clarlees, Boyerm;millwand M, Findlay M, et al: MTA (Ly 231514) An adive agent in advonced non-smallcall bewg Cancer. Proc. ASCO 17: 1793, 1998.
208) Matsuda A, Takenuki T, Tanaka M, et al: Synthescs of new broad spectwn antineopla§lic nudeobides., DMDC its denivatcves J. Med. Chem. 34: 1793, 1998. Tanaka M, Matsuda A, Feoao: Tetal Antitumor of a novel nucleotide. CNDAC against murine and
P.471 掲載の参考文献
2) Huggins C, Hodges CL: Studies on prostatic cancer, 1. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res. 1: 293-297, 1941.
3) Clark JH, Schrader WT, O'Malley BW: Mechanisms of action of steroid hormones. In: Williams Textbook of Endocrinology, 8th edition (eds. by Wilson JD, Foster DW) , W. B. Saunders Company, Philadelphia, 1992, pp. 35-90.
6) Henderson IC, Harris JR: Principles in the management of metastatic disease. In Breast Disease, 2nd ed. (eds. by Henderson IC, Harris JR) , Lippincott, New York, 1990, pp. 547-677.
13) Swain SM: Endocrine therapies of cancer. In Cancer chemotherapy and biotherapy principles and practice (eds. by Chabner BA, Longo DL) , Lppincott-Raven, Philadelphia, 1996, pp. 59-108.
15) Hard GC, Iatropoulos MJ, Jordan K, et al: Major difference in the hepatocarcinogenicity and DNA adduct forming ability between toremifene and tamoxifen in female Crl: CD (BR) Rats. Cancer Res. 53: 4534-4541, 1993.
19) 野村靖夫, 冨永 健, 阿部令彦・他: 進行・再発乳癌に対するNK 622 (クエン酸トレミフェン) の臨床評価-タモキシフェンとの二重盲検法による比較試験-. 癌と化学療法 20: 247-258, 1993.
20) 浅石和昭, 冨永 健, 阿部令彦・他: タモキシフェン療法耐性の乳癌症例に対する高用量NK 622 (クエン酸トレミフェン) の有効性と安全性. 癌と化学療法 20: 91-99, 1993.
30) Watanabe T, Adachi I, Tajima K, et al: Improving the quality of life during chemoendocrine therapy for metastatic breast cacner: arandomized comparison of tamoxifen (TAM) versus medroxyprogesterone acetate (MPA) in combination with doxorubicin (ADM) plus cyclophosphamide. Proc. Am. Soc. Clin. Oncol. 13: 90, 1994.
33) Watanabe T, Adachi I, Taguchi T, et al: 144-SR (leuprorelin sustained release formulation) in premenopausal patients with metastatic breast cancer (MBC) . Breast Cancer Res. Treat. 37: 74, 1995.
37) 青山英昭: 進行・再発乳癌に対するCGS 16949 Aの治療効果-多施設共同研究による後期第二相試験-. 癌と化学療法 21: 477, 1994.
56) Soper JT, Christensen CW: Steroid receptors and endometrial cancer. Clin. Obstet. Gynecol. 13: 825-842, 1986.
59) ThigPen JT, Homesley HD: Arandomized study of medroxyprogesterone acetate (MPA) 200 mg versus 1000mg in the treatment of advanced, persistent or recurrent carcinoma of the endometrium. In : Gynecologic Oncology Group Statistical Report, p 177. Buffalo. Gynecologic Oncology Group, 1990.
60) ThigPen JT, Blessing J, DiSaia P: Oral medroxyprogesterone acetate in advanced or recurrent endometrial carcinoma: Results of therapy and correlation with estrogen and progesterone levels. The gynecologic oncology experience. In: Endocrinology of Malignancy (eds. by baulieu EE, Slacobelli S, McGuire WL) , Park Ridge, NJ, Parthenon, 1986, p. 446.
66) Kline RC, Freedman RS, Jones LA, et al: Treatment of recurrent or metastatic poorly differentiated adenocarcinoma of the endometrium with tamoxifen and medroxyprogesterone acetate. Cancer Treat. Rep. 71: 327-328, 1987.
P.489 掲載の参考文献
1) 漆崎一朗, 塚越茂: 癌とBRM. サイエンスフォーラム, 東京, 1982.
2) 曽根三郎, 小倉 剛: 臨床免疫, 第XV腫瘍免疫: 担癌生体の免疫能. 日本臨牀 (増刊号) : 137-143, 1990.
5) Foon KA: Biological response modifiers: anew immunotherapy. Cancer Res. 49: 1621-1639, 1989.
7) Herberman RB: Design of clinical trials with biological response modifiers. Cancer Treat. Rep. 69: 1161-1164, 1985.
8) Talmadge JE, Herberman RB: The preclinical screening laboratory: evaluation of immunomodulatory and therapeutic properties of biological response modifiers. Cancer Treat. Rep. 70: 171-181, 1986.
12) Cui J, Shin T, Kawano T, et al: Requirement for Vα14 NKT cells in IL-12-mediated rejection of tumors. Science 278: 1623-1626, 1997.
13) Sone S, Yanagawa H, Nii A, et al: Induction of interleukin-2 activated killer effector activity and its regulatory mechanism. Gann Monogr. Cancer Res. 40: 81-93, 1993.
17) Grimm EA, Crump W III, Durett A, et al: Transforming growth factor (TGF-β) inhibits the in vitro induction of lymphokine-activated killing activity. Cancer Immunol. Immunother. 27: 53-58, 1988.
18) Itoh K, Tilden AB, Balch CM: Role of interleukin-2 and a serum suppressive factor on the induction of activated killer cell cytotoxicity for human melanoma cells. Cancer Res. 45: 3173-3178, 1985.
19) Sone S, Yanagawa H, Nii A, et al: Induction of interleukin 2-activated effector activity and its regulatory mechanisms (eds. by Ogura T, Takaku F) . Regulation of Human Cancer by Cytokines 40: 81-93, 1993.
20) Chan SH, Kobayashi M, Santoli D, et al: Mechanism of interferonγ production by natural killer cell stimulatory factor (NKSF/IL12) . Role of transcription and mRNA stability in the synergistic interaction between NKSF and IL-2. J, Immunol. 148: 92-98, 1992.
21) Yamamura Y, Ogura T, Sakatani M, et al: Randomized controlled study of adjuvant immunotherapy with Nocardia rubra cell wall skeleton for inoperable lung cancer. Cancer Res. 43: 5575-5579, 1983.
22) 桝野富弥, 岸本 進, 小倉 剛・他: 肺癌の癌性胸膜炎に対するLC 9018の治療効果-多施設によるphase III ran- domized controlled study. Biotherapy 4: 29-37, 1990.
23) 生越喬二: 細菌製剤および合成化合物による治療-BCG, OK-432, PSK, Lentinan, Bestatin, Levamisole, SPG, MDP, etc-. 癌と化学療法 12: 273-280, 1998.
24) Parkinson DR: Levamisole. In: Biological Therapy of Cancer (ed. by DeVita VT, Hellman S, Rosenberg SA) , JB Lippincott, Philadelphia, 1995, pp. 795-801.
25) 赤座英之, 岩崎明郎: BCGと膀胱癌-その後の展開. Biotherapy 9: 737-745, 1995.
26) Herr HW: lnstillation therapy for bladder cancer. In: Biological Therapy of Cancer (ed. by DeVita, Hellman S, Rosenberg SA) , JB Lippincott, Philadelphia, 1995, pp. 705-711.
27) Schlom J: Monoclonal antibodies in cancer therapy: basic principles. In: Biological Therapy of Cancer (ed. by DeVita VT, Hellman S, Rosenberg SA) , JB Lippincott, philadelphia, 1995, pp. 507-521.
28) Houghton AN, Chapman PB: Clinical applications of monoclonal antibodies in cancer. In: Biological Therapy of Cancer (ed. by DeVita VT, Hellman S, Rosenberg SA) , JB Lippincott, Philadelphia, 1995, pp. 576-590.
33) Caufield J, Barna B, Murthy S, et al: Phase-Ia-Ibtrial of an anti-GD 3 monoclonal antibody in combination with interferon-α in patients with malignant melanoma. J. Biol. Resp. Modif. 9: 319-328, 1990.
34) Alexander HR, Pass HI: Biologic therapy with TNF: systemic administration and isolation-perfusion. In: Biological Therapy of Cancer (ed. by DeVita VT, Hellman S, Rosenberg SA) , JB Lippincott, Philadelphia, 1995, pp. 329-345.
35) Denardo SJ, O'Grady LF, Richman CM, et al: Radioimmunotherapy for advanced breast cancer using 1-131-ChL 6 antibody. Anticancer Res. 17: 1745-1751, 1997.
36) Pai LH, Pastan I: Monoclonal antibodies in cancer therapy: Immunotoxins and recombinant toxins. In: Biological Therapy of Cancer (ed. by DeVita VT, Hellman S, Rosenberg SA) , JB Lippincott, Philadelphia, 1995, pp. 521-533.
37) Markman M, Reichman B, Ianotti N, et al: Phase I trial of recombinant tumor necrosis factor administered by the intraperitoneal route. Reg. Cancer Treat. 2: 174-177, 1989.
41) 早川正道: 腎細胞癌に対する免疫療法の現状と今後の課題. 日本医事新報 3499: 13-18, 1991.
42) Savage PD, Muss HB: Biologic therapy with interferon-α and β: Renal cell cancer. In: Biological Therapy of Cancer (ed. by DeVita VT, Hellman S, Rosenberg SA) , JB Lippincott, Philadelphia, 1995, pp. 373-387.
48) Marincola FM, Rosenberg SA: Biologic therapy with interleukin-2: clinical application, melanoma. In: Biological Therapy of Cancer (ed. by DeVita VT, Hellman S, Rosenberg SA) , JB Lippincott, Philadelphia, 1995, pp. 250-262.
56) Fujiki F, Mukaida N, Hirose K, et al: Prevention of adenocarcinoma colon 26-induced cachexia by interleukin 10gene transfer. Cancer Res. 57: 94-99, 1997.
58) Atkins MB, Robertson MJ, Gordon M, et al: Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies. Clin. Cancer Res. 3: 409-417, 1997.
59) Atkins MB, Trehu EG, Mier JW: Combination cytokine theapy. In: Biological Therapy of Cancer (ed. by DeVita VT, Hellman S, Rosenberg SA) , JB Lippincott, Philadelphia, 1995, pp. 443-466.
72) Jaffee EM, Hurwitz H, Pardoll DM: Gene therapy of cancer: gene modification of tumors. In: BiologicalTherapy of Cancer (ed. by DeVita VT, Hellman S, Rosenberg SA) , JB Lippincott, Philadelphia, 1995, pp. 4774-4783.
76) Yano S, Nishioka Y, Nokihara H, et al: Macrophage colony-stimulating factor gene transduction into human lung cancer cells differentially regulates metastasis formations in various organ microenvironments of natural killer celLdepleted SCID mice. Cancer Res. 57: 784-790, 1997.
77) 川上正舒, 早田邦康: 癌悪液質とサイトカイン-TNFと代謝. Biotherapy 6: 1230-1237, 1992.
78) 漆崎一朗: サイトカインの神経, 内分泌, 免疫相関. Biotherapy 6: 1178-1187, 1992.
P.502 掲載の参考文献
1) 矢守隆夫, 上原至雅, 済木育夫・他: わが国における制がん剤候補物質のスクリーニング成績・第7報. 癌と化学療法 25 (Suppl. I) : 1998.
2) Boyd MR: Status of the NCI preclinical antitumor drug discovery screen. Principles & Practice of Oncology 3: 1-12, 1989.
5) 矢守隆夫: ヒト培養がん細胞パネルによるスクリーニング. 癌と化学療法 24: 129-135, 1997.
P.509 掲載の参考文献
1) 世界医師会総会: ヘルシンキ宣言, ヘルシンキ, 1964, 東京, 1975, ベニス, 1983.
2) Silverman WA: Human experimentation: A Guided Step into the Unknown. Oxford University Press, New York, 1985.
4) 星野一正: 医療の倫理 (岩波新書201) . 岩波書店, 東京, 1991.
5) 厚生省令第28号平成9年3月27日: 医薬品の臨床試験の実施の基準に関する省令, 1997.
6) 中央薬事審議会答申平成9年3月13日: 医薬品の臨床試験の実施の基準 (GCP) の内容, 1997.
7) 厚生省薬務局新医薬品課長通知薬新薬第9号平成3年2月4日: 抗悪性腫瘍薬の臨床評価ガイドライン, 1991.
8) 厚生省医薬品安全局GCP研究会: 改訂GCPハンドブック. 薬業時報社, 東京, 1997.
9) 厚生省薬務局GCP研究会: 医師のための治験ハンドブック. 改訂第2版, ミクス, 東京, 1997.
10) ICH (International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuti- cals for Human Use) : Guideline for Good Clinical Practice. IFPMA, Geneva, 1996.
11) 日本臨床腫瘍研究会: 第9回日本臨床腫瘍研究会プログラム・抄録. 平成8年8月, 東京, 1997.
12) 下山正徳, 田島絹子, 恒松隆一郎・他: 厚生省がん研究助成金指定研究「固形がんの集学的治療の研究」班における臨 床試験計画 (プロトコール) の作成と実施, 並びに結果の統計解析とその評価に関するガイドライン (改訂第3版) 第1部プロトコールの作成に関する医学的並びに科学的事項とその審査. 癌の臨床 42: 197-229, 1996.
13) がん薬物療法研究会: がん臨床試験ガイド-よりよいがん治療を求めて-. Churchill Communications Japan, 東京, 1997.
P.572 掲載の参考文献
1) 藤井博文, 佐々木康綱: 薬理学的マーカーを用いたがん化学療法. 臨床医 21: 80-83, 1995.
2) 国兼浩嗣, 西條長宏: 癌化学療法の新しい標的. 化学療法の領域 9: 13-19, 1993.
3) 佐々木康綱: 抗癌剤の臨床薬理学-Oncological Pharmacology, 化学療法の進歩-新版. メジカルレビュー社, 東京, 1993, pp. 106-112.
4) Ratain MJ: Therapeutic relevance of pharmacokinetics and pharmacodynamics. Semin. Oncol. 19: 8-13, 1992.
7) 佐々木康綱: 抗癌剤の臨床薬理学. 図説臨床癌シリーズno. 1癌化学療法の進歩-新版-, メジカルレビュー社, 1993, pp. 106-122.
8) 高田寛治: 序. 薬物動態学. 基礎と応用, 薬業時報社, 東京, 1995, pp. 1-2.
9) Rowland M, Tozer T: Clinical pharmacokinetics concepts and applications (second edition) ,. Lea & Febiger, 1989.
10) 高田寛治: 薬物動態学的1-コンパートメント・モデル. 薬物動態学基礎と応用, 薬業時報社, 東京, 1995, pp. 3-50.
11) Gibaldi M, Perrier D: Pharmacokinetics. Marcel Dekker Inc, New York, 1975.
12) Akaike H: An information criterion (AIC) ,. Math. Sci. 14 (153) : 5-9, 1976.
17) 高田寛治: 薬物動態学的2-コンパートメント・モデル. 薬物動態学基礎と応用, 薬業時報社, 東京, 1995, pp. 51-78.
18) 山岡 清: マイコンによる薬物体内動態解析法. 南江堂, 東京, 1987.
19) 山岡 清, 谷川原祐介: マイコンによる薬物速度論入門. 南江堂, 東京, 1987.
21) 越前宏俊: TDM講習テキスト-TDMの考え方と臨床応用の基礎-. ダイナボット株式会社.
24) 中川 徹, 小柳義夫: 最小2乗法による実験データ解析. 東京大学出版会, 東京, 1982.
27) 高田寛治: ノンコンパートメント解析法. 薬物動態学基礎と応用. 薬業時報社, 東京, 1995, pp. 79-92.
30) Wagner JG: Pharmacokinetics for the pharmaceutical scientist. Technomic, Lancaster, 1988.
31) 高田寛治: コンパートメント解析における非線形最小二乗法を用いる曲線あてはめ計算. 薬物動態学基礎と応用. 薬業時報社, 東京, 1995, pp. 153-155.
33) Pfeffer M, Nardella PA, et al: Etoposide (VP-16) ,. Academic Press Inc, Ltd, London, 1984.
37) Hande KR: Etoposide pharmacology. Semin. Oncol. 19 (6 Suppl. 13) : 3-9, 1992.
39) Clark PI: Clinical pharmacology and schedule dependency of the podophyllotoxin derivatives. Semin. Oncol. 19 (2Suppl. 6) : 20-27, 1992.
48) Lucas S, Donehower R, et al: Absolute bioavailability (ABA) , liquid-filled soft geratin capsules at full therapeutic doses in patients with solid tumors. Ann. Oncol. 3 (supPl. 1) : 125, 1992.
49) 中島 創, 西條長宏: 臨床薬理学に基づく至適投与法の決定法. がん治療のState of the art-Medical Oncologistの育成を目指して-, 協和企画通信, No. 4, 1993.
50) Wan SH, Huffma DH, et aI: Effect of route of administration and effusions on methotrexate pharmacokinetics. Cancer Res. 34: 3487-3491, 1974.
52) Van Echo DA, Egorin MJ, et al: Phase I clinical and pharmacological trial of carboplatin daily for 5 days. Cancer Treat. Rep. 6811103-1114, 1984.
54) 厚生省薬務局新医薬品課編: 新医薬品承認審査概要 (SBA) , No. 1「塩酸イリノテカン」. 日本公定書協会, 1994.
55) Goodman LS, Gilman A: The pharmacological basis of therapeutics. Macmillan Publishing Co, Inc, 1985.
57) Nierenberg DW: Competitive inhibition of methotrexate accumulation in rabbit kidney slices by nonsteroidal anti-inflamatory drugs. J. Pharmacol. Exp. Ther. 226: 1-6, 1983.
59) Pitman SW, Frei E: Weekly methotrexate-calcium leucovorin rescue: Effect of alkalinization on nephrotoxicity;Pharmacokinetics in the CNS;and use in CNS non-Hodgkin 's lymphoma. Cancer Treat. Rep. 611695-701, 1977.
61) 久保木芳徳, 藤沢隆一: 唾液の採取法と取り扱い. 臨床検査 30 (9) : 937-942, 1986.
62) 西原カズヨ: 唾液中の薬物濃度の測定. 臨床検査 30 (9) : 961-970, 1986.
65) Frauendienst-Egger G, Bartels H, et al: Methotrexate concentrations in serum and saliva in children treated with high doses of methotrexate. J. Clin. Chemistry Clin. Biochemistry 27: 228-229, 1989.
73) Malet-Martino MC, Bernadou J, et al: 1gF NMR spectrometry evidence for bile acid conjugates of α-fluoro-β-alanine as the main biliary metabolisms of antineoplastic fluoropyrimidines in humans. Drug Metab. Dispos. 16: 78-84, 1988.
78) Hull WE, Port RE, et al: Metabolites of 5-fluorouracil in plasma and urine, as monitored by lgF nuclear magnetic resonance spectroscopy, for patients receiving chemotherapy with or without methotrexate pretreatment. Cancer Res. 48: 1680-1688, 1988.
79) Hull WE, Port RE, et al: in vitro 1gF-NMR study of 5-fluorouracil metabolism in liver and implanted tumors of the mouse. Proc. Soc. Magn. Reson. Med. 3: 594-595, 1986.
80) Malet-Martino MC, Armand Jp, et al: Evidence for the importance of 5 '-deoxy-5-fluorouridine catabolism in humans from 19F nuclear magnetic resonance spectrometry. Cancer Res. 46: 2105-2112, 1986.
84) DeForni M, Martino R, et al: Phosphorus-31 nuclear magnetic resonance spectroscopy (31P NMR) : asuitable technique for quantification of ifosfamide and its phosphorated metabolisms in human urine. In: Recent advances in chemotherapy, anticancer section (eds. by Rubinstein & Adam) , E. Lewin-Epstein Ltd, Jerusalem, 1989b, pp. 752. 1-752. 2.
88) Goldstein DS, Coronado L, et al: 6-[Fluorine-18]fluorodopamine pharmacokinetics and dosimetry in humans. J. Nucl. Med. 35: 964-973, 1994.
90) Ding YS, Fowler JS, et al: Synthesis and PET studies of fluorine-18-BMY 148021a potential antipsychotic drug. J. Nucl. Med. 34: 246-254, 1993.
93) Tilsley DW, Harte RJ, et al: New techniques in the pharmacokinetic analysis of cancer drugs. IV. Positron emission tomography. Cancer Surv. 17: 425-442, 1993.
94) 近藤啓吾, 鈴木良彦・他: PET. 臨床画像 12: 174-180, 1995.
103) 杉山雄一, 稲葉 實: In vivo in vitro pharmacokinetics: In vitro殺細胞kineticsデータとpharmacokineticsデータを基にしたin vivo殺細胞効果の予測. Current review癌化学療法1990~91 (西條長宏, 鶴尾 隆, 編) . 中外医学社, 東京, 1990.
104) 杉山雄一, 稲葉 實: 前臨床から臨床へ薬理動態の基礎研究. 図説臨床(癌) シリーズNo. 1癌化学療法の進歩, メジカルビュー社, 東京, 1992.
106) Egorin MJ, Echo DA, et al: Pharmacokinetics and dosage reduction of cis-diammine (1, 1-cyclobutanedicalboxylato) platinum in patients with impaired renal function. Cancer Res. 44: 5432-5438, 1984.
107) Taguchi J, Saijo N, et al: Prediction of hematologic toxicity of carboplatin by creatinine cleatinine rate. Jpn. J. Cancer Res. 78: 977-982, 1987.
109) Sasaki Y, Amano T, et al: Phase I study and pharmacological analysis of cis-diammine (glycolato) platinum (254-S;NSC 375101 D) administered by 5-day continuous intravenous infusion. Cancer Res. 51: 1472-1477, 1991.
112) Bennett CL, Sinkule JA, et al: Phase I clinical and pharmacological study of 72-hour continuous infusion of etoposide in patients with advanced cancer. Cancer Res. 47: 1952-1956, 1987.
114) Au JL-S, Rustum YM, et al: Clinical pharmacological studies of concurrent infusion of 5-fluorouracil and thymidine in the treatment of colorectal carcinoma. Cancer Res. 42: 2930-2937, 1982.
115) Ratain MJ, Vogelzang NJ: Phase I and pharmacological study of vinblastine by prolonged continuous infusion. Cancer Res. 46: 4827-4830, 1986.
116) Egorin MJ, Van Echo DA, et al: Human pharmacokinetics, excretion, and metabolism of anthracycline antibiotic menogaril (7-OMEN, NSC 269148) and their correlation with clinical toxicities. Cancer Res. 46: 1513-1520, 1986.
119) Egorin MJ, Sigman LM, et al: Phase I clinical and pharmacokinetic study of hexamethylene bisacetamide (NSC95580) administered as a five-day continuous infusion. Cancer Res. 47: 617-623, 1987.
120) Rowinsky EK, Ettinger DS, et al: Prolonged infusion of hexamethylene bisacetamide: Aphase I and pharmacological study. Cancer Res. 47: 5788-5795, 1987.
121) Pendyala L, Mdajewics S, et al: Effect of renal function impairment on iproplatin pharmacokinetics and relation to toxicity. Cancer Res. 45: 5936-5938, 1985. to toxicity. Cancer Res. 45: 5936-5938, 1985.
122) Schilsky RL, O'Laughlin K, et al: Phase I and pharmacological study of thymidine (NSC 21548) and cisdiam-minedichloroplatinum (II) in patients with advanced cancer. Cancer Res. 46: 4184-4188, 1986.
125) Ohtsu T, Sasaki Y, et al: Clinical pharmacokinetics and pharmacodynamics of paclitaxel: A3-hour infusion versus a 24-hour infusion. Clin. Cancer Res. 1: 599-606, 1995.
126) Extra JM, Rousseau F, et al: Phase I and pharmacokinetic study of Taxotere (RP 56976;NSC 628503) given as a short intravenous infusion. Cancer Res. 53: 1037-1042, 1993.
136) van Groeningen CJ, Pinedo HM, et al: Pharmacokinetics of 5-fluorouracil assessed with a sensitive mass spectrometric method in patients on dose escalation schedule. Cancer Res. 48: 6956-6961, 1988.
138) 福岡正博: 化学療法. 肺癌 32: 605, 1992.
140) Coleman CN, Halsey J, et al: Relationship between the neurotoxicity of hypoxic cell radiosensitixer SR 2508 and pharmacokinetic profile. Cancer Res. 43: 319-322, 1987.
152) Lu K, Yap HY, et al: Clinical pharmacokinetics of vinblastine by continuous intravenous infusion. Cancer Res. 43: 1405-1408, 1983.
156) Spears CP, Gustavsson BG, et al: Mechanisms of innate resistance to thymidylate synthase inhibition after 5-fluorouracil. Cancer Res. 48: 5894-5900, 1988.
157) Liliemark JO, Plunkett W, et al: Relationship of 1-B-D-arabinofuranosylcytosine in plasma to 1-B-Darabinofuranosylcytosine 5 '-triphosphate levels in leukemic cells during treatment with high dose 1-β-Darabinofuranosylcytosine. Cancer Res. 45: 5942-5957, 1985.
159) Plunkett W, Iacoboni S, et al: Pharmacologically directed Ara-C therapy for refractory leukemia. Semin. Oncol. 12 (suppl. 3) : 20-30, 1985.
167) Vokes EE: Interactions of chemotherapy and radiation. Semin. Oncol. 20: 70-79, 1993.
173) Czeka MJ, Jager W, et al: Clinical pharmacokinetics of 5-fluorouracil. Influence of the biomodulating agents interferon, dipyridamole and folinic acid alone and in combination. Arzneimittelforschung 43: 387-390, 1993.
176) Okuda H, Nishiyama T, Ogura K, et al: Lethal drug interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs. Drug. Metab. Dispos. 25: 270-3, 1997.
179) Hill SR, Pollard LA, Bibby MC: Sequence-dependent activity of 5-fluorouracil plus tauromustine in a transplantable well-differentiated murine colon adenocarcinoma. Anticancer Res. 12: 2169-2175, 1992.
182) Bowen D, White JC, et al: A basis for fluoropyrimidine-induced antagonism to methotrexate in Ehrlich ascites tumor cells in vitro. Cancer Res. 38: 219-222, 1978.
183) Bertino JR, Sawicki WL, et al: Schedule-dependent antitumor effects of methotrexate and 5-fluorouracil. Cancer Res. 37: 327-328, 1977.
186) Cano JP, Aubert C, et al: Advantages and limitations of pharmacokinetic studies in the rationalization of anticancer therapy: methotrexate and 5-FU. Cancer Treat. Rep. 65: 33-42, 1981.
187) Bastian G, Demarcq C, et al: Pharmacokinetics of 5-fluorouracil: effect of association with cis-platinum duringlong term infusion. Proc. Am. Soc. Clin. Oncol. 5: 55, 1986.
190) Lichman S, Ratain M, et al: Phase I trial of GM-CSF plus high dose cyclophosphamide in solid tumor. Proc. Am. Soc. Clin. Oncol. 9: 256, 1990.
191) Sladek NE, Powers JF, et al: Plasma concentrations of 4-hydroxycyclophosphamide and phosphoramide mustard in patients repeatedly given high doses of cyclophosphamide in preparation for bone marrow transplantation. Cancer Res. 47: 2723-2726, 1984.
192) Struct RF, Alberts DF, et al: Plasma pharmacokinetics of cyclophosphamide and its cytotoxic metabolites after intravenous versus oral administration in randomized, crossover trial. Cancer Res. 47: 2723-2726, 1987.
195) Bagley CMJ, Bostick FW, et al: Clinical pharmacology of cyclophosphamide. Cancer Res. 33: 226-233, 1973.
198) Dorr RT, Soble MJ, et al: Interaction of cimetidine but not ranitidine with cyclophosphalnide in mice. Cancer Res. 46: 1795-1799, 1986.
200) Cagnoni PJ, Matthes S, et al: Ondansetron significantly reduces the area under the curve (AUC) of cyclophosphamide (CPA) and cisplatin (CDDP) . Proc. Am. Soc. Clin. Oncol. 14: 462, 1995.
202) Dodion P, Riggs Jr C, et al: Interactions between cyclophosphamide and adriamycin metabolism in rats. J. Pharmacol. Exp. Ther. 229: 51-57, 1984.
206) Erlichman C, Moore M, et al: Phase I pharmacokinetic study of cyclosporin-A combined with doxorubicin. Cancer Res. 53: 4837-4842, 1993.
215) Rodman JH, Murry DJ, et al: Pharmacokinetics of high-doses of etoposide and the influence of anticonvulsants in pediatric cancer-patients. Clin. Pharmacol. Ther. 51: 156, 1992.
221) Gianni L, Locatelli A, et al: Order of administration and pharmacokinetics of paclitaxel (P) by 3 h infusion and doxorubicin (D) by iv bolus. Proc. Am. Soc. Clin. Oncol. 14: 169, 1995.
226) Schellens JHM, Ma J, et al: Pharmacokinetics of cisplatin and taxotere (docetaxel) and WBC DNA-adduct formation of cisplatin in the sequence taxotere/cisplatin and cisplatin/taxotere in a phase I/IIstudy in solid tumor patients. Proc. Am. Soc. Clin. Oncol. 13: 132, 1994.
228) 山本 昇, 西條長宏: 癌化学療法の副作用対策. 臨床腫瘍研究最前線-Direction of Medical Oncology-No. 3, 協和企画通信, 東京, 1996.
231) Cresteil T, Monserrat B, et al: Taxol metabolism by human liver microsomes: identification of cytochrome P450 isozymes involved in its biotransformation. Cancer Res. 54: 386-392, 1994.
232) Harris JW, Rahman A, et al: Metabolism of taxol by human microsomes and liver slices: participation of cytochrome P450 3A4 and an unknown P450 enzyme. Cancer Res. 54: 4026-4035, 1994.
234) Letrent SP, Brouwer KLR, et al: Carboplatin (CBDCA) pharmacokinetics and prediction of AUC after highdose CBDCA following high-dose paclitaxel. Proc. Am. Soc. Clin. Oncol. 14: 462, 1995.
235) Kearns CM, Belani CP, et al: Pharmacokinetics of paclitaxel and carboplatin in combination. Semin. Oncol. 22 (Suppl. 12) : 1-4, 1995.
236) Bruno R, Vivier N, et al: Lack of influence of dexamethasone premedication on docetaxel (Taxotere) pharmacokinetics. 9th NCI-EORTC Symposium on New Drugs in Cancer Therapy, Amsterdam, Netherlands, 1996.
237) Chabner BA: Clinical strategies for cancer treatment: the role of drugs. In: Cancer chemotherapy (eds. by Chabner & Collins) , J. B. Lippincott Company, Philadelphia, 1990, pp. 1-15.
239) Jacobs C, Kalman SM, et al: Renal handling of cis-diamminedichloroplatinum (II) . Cancer Treat Rep. 64: 1223-1226, 1980.
240) Goren MP, Wright RK, et al: Potentiation of ifosfamide neurotoxicity, hematotoxicity, and tubular nephrotoxocity by prior cis-diamminedichloroplatinum (2) therapy. Cancer Res. 47: 1457-1460, 1987.
242) Egorin MJ, Van Echo DA, et al: Pharmacokinetics and dosage reduction of cis-diammine (1, 1-cyclobutanedicarboxylato) plutinum in patients with impaired renal function. Cancer Res. 44: 5432-5438, 1984.
244) Benjamin RS: A practical approach to adriamycin toxicity. Cancer Chemother. Rep. 6: 191-194, 1975.
245) Twelves CJ, Dobbs NA, et al: Clinical pharmacokinetics of epirubicin: Dose nomogram based on liver biochemistory test. Proc. Am. Soc. Clin. Oncol. 10: 99, 1991.
247) D 'Incalci M, Cosmo R, et al: Pharmacokinetics of etoposide in patients with abnormal renal and hepatic function. Cancer Res. 46: 2566-2571, 1986.
251) Bagley CM, Bostick FW, et al: Clinical pharmacology of cyclophosphamide. Cancer Res. 33: 226-235, 1973.
252) Robieux I, Sorio I, et al: Pharmacokinetics of vinorelbine in breast cancer patients with liver metastasis. Proc. Am. Soc. Clin. Oncol. 14: 458, 1995.
254) Francis P, Bruno R, et al: Pharmacodynamics (PD) of docetaxel (Taxotere) in patients (pts) with liver metastasis (METS) . Proc. Am. Soc. Clin. Oncol. 13: 138, 1994.
258) Balducci L, Parker M, et al: Pharmacology of antineoplastic agents in the elderly patient. Semin. Oncol. 16: 76-84, 1989.
268) 長島聖二, 西條長宏: 癌治療の臨床試験計画. 臨床腫瘍研究最前線-Direction of Medical Oncology-No. 1, 協和企画通信, 東京, 1995.
270) Sasaki Y, Miya T, et al: Limited sampling strategy (LSS) for mitomycin C (MMC) pharmacokinetics. 肺癌 32: 785, 1992.
271) Egorin MJ, Forrest A, et al: A limited sampling strategy for cyclophosphamide pharmacokinesics. Cancer Res. 49: 3129-3133, 1989.
272) Ratain MJ, Vogelzang NJ: Limited sampling model for vinblastine pharmacokinetics. Cancer Treat. Rep. 71: 935-939, 1987.
277) Joel SP, Heap L, et al: A limited sampling strategy for the calculator of etoposide pharmacokinetics. Proc. Am. Soc. Clin. Oncol. 9: 67, 1990.
278) Ratain MJ, Staubus AE, et al: Limited sampling models for Amonafide (NSC 308847) pharmacokinetics. Cancer Res. 48: 4127-4130, 1988.
285) 大津智子, 佐々木康綱: 抗癌剤のPharmacodynamics. 癌と化学療法 20: 1741-1749, 1993.
288) 高田寛治: ポピュレーションファーマコキネティックス. 薬物動態学基礎と応用. 薬業時報社, 東京, 1995, pp. 163- 170.
289) Periclou AP, Avramis VI: Population pharmacokinetic (PPK) analysis of cytosine arabinoside (ara-C) following high dose (HDara-C) and continuous infusion (CI) in pediatric patients with leukemias. Proc. Am. Soc. Clin. Oncol. 14: 463, 1995.
291) Bruno R, Hille D, et al: Population pharmacokinetics/pharmacodynamics (PK/PD) of docetaxel (Taxotere) in phase II studies. Proc. Am. Soc. Clin. Oncol. 14: 457, 1995.
294) Plunkett W, Iacoboni S, et al: Pharmacologically directed ara-C therapy for refractory leukemia. Semin. Oncol. 12 (2Suppl. 3) : 20-30, 1985.
297) Slevin ML, Joel SP, et al: Therapeutic monitoring of infusional etoposide in previously untreated small cell lung cancer (SCLC) . Proc. Am. Soc. Clin. Oncol. 13: 133, 1994.
299) Scher HI, Jodrell DI, et al: Use of adaptive control with feedback to individualize suramin dosing. Cancer Res. 52: 64-70, 1992.
309) Chabot GG: Factors involved in clinical pharmacology variability in oncology (review) . Anticancer Res. 14: 2269-2272, 1994.
310) Shimada T, Yamazaki H, et al: Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30Caucasians. J. Pharmacol. Exp. Ther. 270: 414-423, 1994.
313) Hadidi AFA, Coulter CEA, et al: Phemotypically deficient urinary elimination of carboxyphosphamode after cyclophosphamide administration to cancer patients. Cancer Res. 48: 5167-5171, 1988.
317) Milano G, Etienne MC: Evolution from pharmacokinetics to pharmacogenetics. The example of 5-fluorouracil. Rev. Med. Interne 15: 287-291, 1994.
320) Allerheiligen S, Johnston R, et al: Gemcitabine pharmacokinetics are influenced by gender, body surface area and duration of infusion. Proc, Am. Soc. Clin. Oncol. 13: 136, 1994.
322) Ratain MJ, Mick R, et al: Phase I study of amonafide dosing based acetylator phenotype. Cancer Res. 53: 2304-2308, 1993.
325) Cardoso SS, Scheving LE, et al: Mortality of mice as influenced by the hour of the day of drug (ara-C) administration. Pharmacologist 12: 302, 1970.
327) Levi FA, Hrushesky WJM: Cisplatin urinary pharmacokinetics and nephrotoxicity: Acommon circadian mechanism. Cancer Treat. Rep. 66: 1933-1938, 1982.
328) Levi FA, Hrushesky WJM: Reduction of cis-diamminedichloroplatinum nephrotoxicity in rats by optimal circadian drug timing, Cancer Res. 42: 950-955, 1982.
331) Petit E, Milano G, et al: Circadian rhythm-varying plasma concentration of 5-fluorouracil during a five-day continuous venous infusion at a constant rate in cancer patients. Cancer Res. 48: 1676-1679, 1988.
332) Harris B, Song R, et al: Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian var{ation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion. Cancer Res. 50: 197-201, 1990.
333) Metzger G, Comisso C, et al: Difference in time course of plasma levels of 5-fluorouracil (5-FU) during constant or chronomodulated infusion in cancer patients. Proc. Am. Assoc. Cancer. Res. 33: 534, 1992.
334) Vassal G, Challine D, et al: Chronopharmacology of high-dose busulfan in children. Cancer Res. 53: 1534-1537, 1993.
337) Huben RP, Dragone N, et al: Continuous infusion FUDR chemotherapy in the treatment of metastatic renal cell carcinoma. J. Urol. A 413, 1990 (abstr) .
340) Hrushesky WJM, Bjarnason G, et al: Fluoropyrimidine circadian continuous infusion shape affects its toxicity profile. Proc. Am. Soc. Clin. Oncol. 12: 248, 1993.
341) Wasen C, Hrushesky WJM, et al: Circadian modification of intra-arteria15-fluoro-2 '-deoxyuridine infusion rate reduces its toxicity and perrnits higher dose intensity. J Infus. Chemorher. 2: 69-75, 1992.
342) Focan C, Levi F, et al: Chronotherapy of hepatic metastasis from colorectal cancer by local and general infusion. Proc. Am. Soc. Clin. Oncol. 11: 542, 1992.
343) Levi F, Soussan A, et al: Programmable-in time pumps for chronotherapy of patients with colorectal cancer with 5-day circadian-modulated venous infusion of 5-fluorouracil. Proc. Am. Soc. Clin. Oncol. 8: 429, 1989.
344) Bjarnason GA, Kerr I, et al: Phase I study of 5-fluorouracil (5-FU) and leucovorin (LV) by 14 day continuous infusion chronotherapy in patients with metastatic adenocarcinoma. Eur. J. Cancer 2: A528, 1991.
346) Levi F, Brienza JL, et al: Circumvention of clinical resistance of metastatic colorectal cancer to 5-fluorouracil (5-FU) with circadian rhythm modulated chemotherapy. Proc. Am. Soc. Clin. Oncol. 11: A500, 1992.
347) Hrushesky WJM, von Roemeling R, et al: Circadian chronotherapy: From animal experiments to human cancer chemotherapy, In: Chronopharmacology Cellular and Biochemical Interactions (ed. by Lemmer B) , Decker, New York, 1989, pp. 439-473.
352) Focan C : Chronotherapy in lung and ovarian cancer. J. Cancer Res. Clin. Oncol. 116 (suppl 2, part II abstr) : 16. 20, 24, 1990.
353) Brummer PD, Levi F, et al: Aphase I trial of 21-day continuous venous infusion ofα. -interferon at circadian rhythm modulated rate in cancer patients. J. ImmunoL 10: 440-447, 1991.
355) Collins JM, Zaharko DS, et al: Potential roles for preclinical pharmacology in phase I clinical trials. Cancer Treat. Rep. 70: 73-80, 1986.
360) Donehower R, Grove W, et al: Successful use of pharmacologically guided dose escalation (PGDE) in a phase Itrial of CI-958. Proc. Am. Soc. Clin. Oncol. 12: 139, 1993.
363) Ames MM, Lopronzi CL, et al: Phase I and clinical evaluation of piroxantron hydrochloride (oxantrazole) . Cancer Res. 50: 3905-3909, 1990.
364) Hantel A, Donehower RC, et al: Phase I study and pharmacodynamics of piroxantrone (NSC 349174) , anewanthrapyrazole. Cancer Res. 50: 3284-3288, 1990.
365) Erlichman C, Moore M, et al: Phase I pharmacokinetic and pharmacodynamic study of a new anthrapyrazole CI-937 (DuP 937) . Cancer Res. 51: 6317-6322, 1991.
369) Zervos PH, Faries D, Dorr FA, et al: Practical use of the modified continual reassessment method for dose escalation in a phase I trial with LY 231514. Proc. Am. Soc. Clin. Oncol. 14: 473, 1995.
370) Rinaldi D, Burris H, Dorr FA, et al: Aphase I evaluation of LY 231514 administered every 21 days, utilizing the modified continual reassessment method for dose escalation. Proc. Am. Soc. Clin. Oncol. 14: 474, 1995.
371) Sinbald di V, Eisenburger M, Moore-Cooper S, et al: Phase I study of a pharmacologically derived, dairy×5, monthly schedule of suramin in patients with hormone-refractory prostate cancer. Proc. Am. Soc. Clin. Oncol. 14: 469, 1995.
372) 佐々木康綱: 抗がん剤の臨床薬理学. 臨床腫瘍学, 第1版, 癌と化学療法社, 東京, 1996, pp. 335-352.
128-a) Gupta EM, Lestingi T, et al: Metabolic fate of irinotecan in humans: Cor relation of glucuronidation with diarrhea. Cancer Res. 54: 3723-3725, 1994.
P.594 掲載の参考文献
1) Calabresi P, Parks RE: Alkylating agents, antimetabolites, hormones and other antiproliferative agents. In: The pharmacological bases of therapeutics (eds by Goodman LS, Gilman A) , Macmillan, New York, 1975, p. 1254.
3) 薬剤の添付文書による
4) Brock N: Oxazaphosphorine cytostatics: past present future. Cancer Res. 49: 1, 1989.
5) Calvin M, Padgett CA, Fancily C: A biologically active metabolize of cyclophosphamide. Cancer Res. 33: 915, 1973.
6) 薬剤の添付文書による
7) 薬剤の添付文書による
9) 薬剤の添付文書による
11) 薬剤の添付文書による
12) 薬剤の添付文書による
13) 薬剤の添付文書による
P.606 掲載の参考文献
3) Demarcq C, Bunch RT, Creswell D, et al: The role of cell cycle progression in cisplatin induced apoptosis in Chinese hamster ovary cells. Cell Growth Differ. 5: 983 993, 1994.
10) Richon VM, Schulte N, Eastman A: Multiple mechanisms of resistance to cis diamrninedichloroplatinum (II) in murine leukemia L1210 cells. Cancer Res. 47: 2056 2061, 1987.
11) Teicher BA, Holden SA, Kelley MJ, et al: Characterization of a human squamous carcinoma cell line resistant to cis diamminedichloroplatinum (II) . Cancer Res. 47: 388 393, 1987.
13) Andrews PA, Velury S, Mann SC, et al: cis Diamminedichloroplatinum (II) accumulation in sensitive and resistant human ovarian carcinoma cells. Cancer Res. 48: 68 73, 1988.
14) Gale GR, Morris CR, Atkins LM, et al: Binding of an antitumor platinum compound to cells as influenced by physical factors and pharmacologically active agents. Cancer Res. 33: 813 818, 1973.
18) Andrews PA, Mann SC, Huynh HH, et al: Role of the Na+, K+ adenosine triphosphatase in the accumulation of cis diamminedichloroplatinum (II) in human ovarian carcinoma cells. Cancer Res. 51: 3677 3681, 1991.
20) Taniguchi K, Wada M, Kohno K, et al: Ahuman canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin resistant human cancer cell lines with decreased drug accumulation. Cancer Res. 56: 4124 4129, 1996.
26) Masuda H, Ozols RF, Lai G M, et al: Increased DNA repair as a mechanism of acquired resistance to cis diamminedichloroplatinum (II) in human ovarian cancer cell lines. Cancer Res. 48: 5713 5716, 1988.
29) Hoffmann J S, Pillaire M J, Maga G, et al: DNA polymeraseβbypasses in vitro a single d (GpG) cisplatin adduct placed on codon 130f the HRAS gene. Proc. Natl. Acad. Sci. USA 92: 5356 5360, 1995.
32) Earhart RH: Instability of cis dichlorodiammineplatinum in dextrose solution. Cancer Treat. Rep. 62: 1105 1106, 1978.
35) Vermorken JB, van der Vijgh WJF, Klein I, et al: Pharmacokinetics of free and total platinum species after short term infusion of cisplatin. Cancer Treat. Rep. 68: 505 513, 1984.
36) Elferink F, van der Vijgh WJF, Klein I, et al: Pharmacokinetics of carboplatin after iv administration. Cancer Treat. Rep. 71: 1231 1237, 1987.
39) Forastiere AA, Belliveau JF, Goren MP, et al: Pharmacokinetic and toxicity evaluation of five day continuous infusion versus intermittent bolus cis diamminedichloroplatinum (II) in head and neck cancer patients. Cancer Res. 48: 3869 3874, 1988.
43) Belt RJ, Himmelstein KJ, Patton TF, et al: Pharmacokinetics of non protein bound platinum species following administration of cis dichlorodiammineplatinum (II) . Cancer Treat. Rep. 63: 1515 1521, 1979.
44) Lokich JJ: Phase I study of cis diamminedichloroplatinum (II) administered as a constant 5 day infusion. Cancer Treat. Rep. 64: 905 908, 1980.
47) Belliveau JF, Posner MR, Ferrari L, et al: Cisplatin administered as a continuous 5 day infusion: plasma platinum levels and urine platinum excretion. Cancer Treat. Rep. 70: 1215 1217, 1986.
54) Aamdal S, Fodstadφ, Kaalhus O, et al: Reduced antineoplastic activity in mice of cisplatin administered with high salt concentration in the vehicle. J. Natl. Cancer Inst. 73: 743 752, 1984.
59) Al Sarraf M, Fletcher W, Oishi N, et al: Cisplatin hydration with and without mannitol diuresis in refractory disseminated malignant melanoma: asouthwest oncology group study. Cancer Treat. Rep. 66: 31 35, 1982.
60) Belt RJ, Taylor S: Randomized trial of hydration and mannitol in preventing cis platinum induced nephrotoxicity. Proc. Am. Assoc. Cancer Res. and ASCO 201388, 1979.
61) Ostrow S, Egorin MJ, Hahn D, et al: High dose cisplatin therapy using mannitol versus furosemide diuresis: comparative pharmacokinetics and toxicity. Cancer Treat. Rep. 65: 73 78, 1981.
65) Salem P, Hall SW, Benjamin RS, et al: Clinical phase I II study of cis dichlorodiammine platinum (II) given by continuous iv infusion. Cancer Treat. Rep. 62: 1553 1555, 1978.
78) Howell SB, Pfeifle CE, Wung WE, et al: Intraperitoneal cis diamminedichloroplatinum with systemic thiosulfate protection. Cancer Res. 43: 1426 1431, 1983.
79) Casper ES, Kelsen DP, Alcock NW, et al: Ip cisplatin in patients with malignant ascites: pharmacokinetic evaluation and comparison with the iv route. Cancer Treat. Rep. 67: 235 238, 1983.
85) Knox RJ, Friedlos F, Lydall DA, et al: Mechanism of cytotoxicity of anticancer platinum drugs l evidence that cis diamminedichloroplatinum (II) and cis diammine (1, 1 cyclobutanedicarboxylato) platinum (II) differ only in the kinetics of their interaction with DNA. Cancer Res. 46: 1972 1979, 1986.
87) Harland SJ, Newell DR, Siddik ZH, et al: Pharmacokinetics of cis diammine 1, 1 cyclobutane dicarboxylate platinum (II) in patients with normal and impaired renal function. Cancer Res. 44: 1693 1697, 1984.
93) Egorin MJ, Van Echo DA, Olman EA, et al: Prospective validation of a pharmacologically based dosing scheme for the cis diamminedichloroplatinum (II) analogue diamminecyclobutanedicarboxylatoplatinum (II) . Cancer Res. 45: 6502 6506, 1985.
104) Evans BD, Raju KS, Calvert AH, et al: Phase II study of JM 8, a new platinum analog, in advanced ovarian carcinoma. Cancer Treat. Rep. 67: 997 1000, 1983.
116) 古瀬清行, 福岡正博, 浅本 仁・他: 肺非小細胞癌に対する254-S・VDS療法とCDDP・VDS療法との比較臨床試験 成績. 癌と化学療法 19: 1019-1026, 1992.
117) 堀内正敏, 三宅浩郷, 太田和雄: 254-S (Cis-diammine glycolato platinum) の聴力障害. 癌と化学療法 19: 1327- 1332, 1992.
119) 平林光司, 岡田悦子, 尾熊隆嘉・他: 白金系抗腫瘍剤 cis-diammine (glycolato) platinum (254-S) の静脈内投与お よび腹腔内投与における体内動態. 癌と化学療法 17: 2221-2227, 1990.
120) Sasaki Y, Amano T, Morita M, et al: Phase I study and pharmacological analysis of cis diammine (glycolato) platinum (254 S;NSC 375101D) administered by 5 day continuous intravenous infusion. Cancer Res. 51: 1472 1477, 1991.
121) Kidani Y, Noji M, Tashiro T: Antitumor activity of platinum (II) complexes of 1, 2 diaminocyclohexane isomers. Jpn. J. Cancer. Res. 71: 637 643, 1980.
122) Gamelin E, Le Bouil A, Boisdron Celle M, et al: Cumulative pharmacokinetic study of oxaliplatin, administered every three weeks, combined with 5 fluorouracil in colorectal cancer patients. Clin. Cancer Res. 3: 891 899, 1997.
124) Boughattas NA, L6vi F, Fournier C, et al: Circadian rhythm in toxicities and tissue uptake of 1, 2 diamminocyclohexane (trans 1) oxalatoplatinum (II) in mice. Cancer Res. 49: 3362 3368, 1989.
P.620 掲載の参考文献
1) 古江 尚, 太田和雄, 田口鐵男・他: 癌化学療法の基礎と臨床. 癌と化学療法社, 東京, 1986, pp. 155-188.
5) Wiliams JW, Dugglerby RG, Cutler R, et al: The inhibition of dihydrofolate reductase by folate analogues: structural requirements for slow and tight binding inhibitors. Biochem. Pharmacol. 25: 2695 2702, 1978.
6) Rutman RJ, Cantarow A, Paschkis KE: Studies on 2 acethylaminofluorene carcinogenesis. III. The utilization of uracil 2 Ci4 by pre neoplastic rat liver. Cancer Res. 14: 119 126, 1954.
12) Au JL, Sadee W: Activation of futrafur (R, S+tetrahydro 2 furanyl) 5 fluorouracil to 5 fluorouracil and butyrolactone. Cancer Res. 36: 2814 2819, 1980.
13) Fujii S, Ikenaka K, Fukushima M, et al: Effect of uracil and its derivatives on antitumor activity of 5 Fu and 1 (2 tetrahydrofuranyl) 5 fluorouracil. Jpn. J. Cancer Res. 69: 763, 1978.
15) 藤田 浩: フッ化ピリミジン化合物抗癌剤の薬理動態. メディカルレビュー社, 東京, 1986, pp. 61-111.
17) Walwick ER, Robert WK, Dekker CA: Cyclization during the phosphorylation of uridine and cytidine polyphosphoric acid: anew route to the O 2 2 ' cyclonucleoside. Proc. Chem. Soc.: 84, 1959.
18) Townsend AJ, Cheng Y C: Sequence specific effects of ara 5 aza CTP and ara CTP on DNA synthesis by purified human DNA polymerase in vitro: visualization of chain elongation on a defined template. Mol. Pharmacol. 32: 330, 1987.
19) Parker WB, Cheng Y C: Inhibition of DNA primase by nucleoside triphosphate and their arabinofuranosyl analogs. Mol. Pharmacol. 31: 146, 1987.
21) Yoshida Y, Yamada J, Watanabe T, et al: Participation of peroxisomalβ-Oxidation system in the chainshortening of PCA16, A metabolite of the cytosine arabinoside prodrug, YNKO 1, in rat liver. Biochem. Pharmacol. 39: 1505 1512, 1990.
22) Oh ishi J, Kataoka T, Tsukagoshi S, et al: Production of N succinyl 1-β-D arabinofuranosylcytosine, a novel metabolite of N4 behenoyl 1-β-D arabinofuranosylcytosine in mice and its biological significance. Cancer Res. 41: 2501, 1981.
25) Elison GB: Biochemistry and pharmacology of purine analogs. Fed. Proc. 26: 898, 1967.
28) Bertino JR, Sawicki WL, Lindquist CA, et al: Schedule dependent antitumor effects of methotrexate and 5 fluorouracil. Cancer Res. 37: 327, 1977.
31) 佐治重豊, 相羽恵介, 荒木 浩・他: 低容量CDDPと5-FU療法の現状について. 癌と化学療法 24: 1892-1900, 1997.
32) Evans RM, Laskin JD, Hakala MT: Relationship of dUMP and free FdUMP pools to inhibition of thymidylate synthetase by 5 fluorouracil. Cancer Res. 41: 3288 3295, 1981.
34) Boarman DH, Allegra CJ: Intracellular metabolism of 5 formyltetrahydrofolate in human breast and colon celllines. Cancer Res. 52: 36 44, 1992.
36) Grem JL, van Groeningen CJ, Ismail AA, et al: The role of interferon-α as a modulator of fluorouracil and leucovorin. Eur. J. Cancer 31 A: 1316, 1995.
38) Houghton JA, Morton CL, Adkins DA, et al: Locus of the interaction among 5 fluorouracil, leucovorin and interferon-α2 a in colon carcinoma cells. Cancer Res. 53: 4243, 1993.
39) Warren RD, Nichols AP, Bender RA: Membrane transport of methotrexate in human lymphoblastoid cells. Cancer Res. 38: 668 671, 1978.
40) Pinedo HM, Zaharko DS, Bull JM, et al: The reversal of methotrexate cytotoxicity to mouse bone marrow cells by leucovorin and nucleosides. Cancer Res. 36: 4418, 1976.
P.632 掲載の参考文献
8) 安藤俊夫: DNA トポロジーの生物効果. 細胞工学 6: 830-838, 1987.
9) 安藤俊夫: DNA トポイソメラーゼの生物機能. 癌と化学療法 18: 1543-1649, 1991.
12) Li LH, Fraser TJ, Olin EJ, et al: Action of camptothecin on mammalian cells in culture. Cancer Res. 32: 2643-2650, 1972.
13) Drewinko B, Freireich EJ, Gottlieb JA: Lethal activity of camptothecin sodium on human lymphoma cells. Cancer Res. 34: 747 750, 1974.
14) Gallo RC, Whang Peng J, Adamson RH: Studies on the antitumor activity mechanism of action, and cell cycle effects of camptothecin. J. Natl. Cancer Inst. 46: 789 795, 1971.
15) Gottlieb J, Guarino A, Call J, et al: Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC 100880) . Cancer Chemother. Rep. 54: 461 470, 1970.
16) Moertel CG, Schutt AJ, Reitemeier RJ, et al: Phase II study of camptothecin (NSC100880) in the treatment of advanced gastrointestinal cancer. Cancer Treat. Rep. 56195 101, 1972.
17) Gottlieb JA, Luce JK: Treatment of malignant melanoma with camptothecin (NSC 100880) . Cancer Chemother Rep. 56: 103 105, 1972.
18) Creaven PJ, Allen LM, Muggia FM: Plasma camptothecin (NSC 100880) levels during a 5 day course of treatment: relation to dose and toxicity. Cancer Chemother. Rep. 56: 573 578, 1972.
19) Muggia, FM, Creaven, PJ, Hansen HH, et al: Phase I clinical trial of weekly and daily treatment with camptothecin (NSC 100880) lCorrelation with preclinical studies. Cancer Chemother. Rep. 56: 515 521, 1972.
21) Kunimoto T, Nitta K, Tanaka T, et al: Antitumor activity of 7 ethyl 10 [4 (1 piperidino) 1 piperidino] carbonyloxy Camptothecin, a novel water soluble derivative of camptothecin, against murine tumors. Cancer Res. 47: 5944 5947, 1987.
22) Furuta T, Yokokura T, Mutai M: Antitumor activity of CPT-11 against rat Walker carcinoma. Gan to Kagaku Ryoho 15: 2757 2760, 1988 (in Japanese) .
23) Bissery MC, Mathieu Boue A, Lavelle F: Experimental antitumor activity of CPT-11 in vitro and in vivo. In Proceedings of the Seventh NCI EORTC Symposium on New Drugs in Cancer Therapy, Amsterdam, 1992 p. 82 (Abstr.) .
27) Kaneda N, Nagata H, Furuta T, et al: Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse. Cancer Res. 50: 1715 1720, 1990.
29) Kawato Y, Aonuma M, Hirota Y, et al: Intracellular roles of SN 38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11. Cancer Res. 51: 4187 4191, 1991.
30) Furuta T, Yokokura T: Effect of administration schedule on the antitumor activity of CPT-11, a camptothecin derivative. Gan to Kagaku Ryoho 17: 121 130, 1990 (in Japanese) .
32) Taguchi T, Wakui A, Hasegawa K, et al: Phase I clinical study of CPT-11. Gan to Kagaku Ryoho 17: 115 120, 1990 (in Japanese) .
36) Rowinsky EK, Grochow LB, Ettinger DS, et al: Phase I and pharmacological study of the novel topoisomerase I inhibitor 7 Cthyl 10 [4 (1 piperidino) 1 piperidino]carbonyloxycamptothecin (CPT-11) administered as aninety minute infusion every 3 weeks. Cancer Res. 54: 427 436, 1994.
38) de Forni M, Bugat R, Chabot GG, et al: Phase I and pharmacokinetic study of the camptothecin derivative irinotecan, administered on a weekly schedule in cancer patients. Cancer Res. 54: 4347 4354, 1994.
41) Bugat R, Suc E, Rougier Ph, et al: CPT-11 (lrinotecan) as second line therapy in advanced colorectal cancer (CRC) : Preliminary results of a multicentric phase II study. Proc. Am. Soc. Clin. Oncol. 13: 200, 1994 (Abstr.) .
42) Rougier Ph, Culine S, Bugat R, et al: Multicentric phase II study of first line CPT-11 (Irinotecan) in advanced colorectal cancer (CRC) : Preliminary results. Proc. Am. Soc. Clin. Oncol. 13: 200, 1994 (Abstr.) .
43) Bugat R, Rougier P, Douilland JY, et al: Efficacy of Irinotecan HCI (CPT-11) in patients with metastatic colorectal cancer after progression while receiving a 5 FU based chemotherapy. Proc. Am. Soc. Clin. Oncol. 14: 222, 1995 (Abstr.) .
44) Conti JA, Kemeny N, Saltz L, et al: Irinotecan (CPT-11) is an active agent in untreated patients (pts) with metastatic colorectal cancer (CRC) . Proc. Am. Soc. Clin. Oncol. 13: 195, 1994 (Abstr.) .
45) Pitot HC, Wender D, O'Connell MJ, et al: Aphase II trial of CPT-11 (Irinotecan) in patients with metastatic colorectal carcinoma: ANorth Central Cancer Treatment Group (NCCTG) study. Proc. Am. Soc. Clin. Oncol. 13: 197, 1994 (Abstr.) .
46) Rothenberg ML, Eckardt JR, Burris III HA, et al: Irinotecan (CPT-11) as second line therapy for pts with 5 FU refractory colorectal cancer. Proc. Am. Soc. Clin. Oncol. 13: 198, 1994 (Abstr.) .
47) Takeuchi S, Takamizawa H, Takeda Y, et al: An early phase II study of CPT-11 for gynecologic cancers. Gan to Kagaku Ryoho 18: 579 584, 1991 (in Japanese) .
48) Takeuchi S, Dobashi K, Fujimoto S, et al: Alate phase II study of CPT-11 on uterine cervical cancer and ovarian cancer. Gan to Kagaku Ryoho 18: 1681 1689, 1991 (in Japanese) .
49) Takeuchi S, Noda K, Yakushiji M, CPT-11 Study Group on Gynecologic malignancy: Late phase II study of CPT-11, topoisomerase I inhibitor, in advanced cervical carcinoma (CC) . Proc. Am. Soc. Clin. Oncol. 11: 224, 1992 (Abstr.) .
50) Kambe M, Wakui A, Nakao I, et al: Alate phase II study of irinotecan (CPT-11) in patients with advanced gastric cancer. Proc. Am. Soc. Clin. Oncol. 12: 198, 1993 (Abstr.) .
51) Sakata Y, Wakui A, Nakao I, et al: Alate phase II study of irinotecan (CPT-11) , in advanced pancreatic cancer. Proc. Am. Soc. Clin. Oncol. 12: 211, 1993 (Abstr.) .
52) Bonneterrre J, Pion JM, Adenis A, et al: Aphase II study of a new camptothecin analogue CPT-11 in previously treated advanced breast cancer patients. Proc. Am. Soc. Clin. Onco1. 12: 94, 1993 (Abstr.) .
55) Nakai H, Fukuoka M, Furuse K, et al: An early phase II study of CPT-11 for primary lung cancer. Gan to Kagaku Ryoho 18: 607 612, 1991 (in Japanese) .
60) Chabot GG, Abigerges D, Gandia D, et al: Pharmacokinetic pharmacodynamic relationships in patients administered with CPT-11, a new camptothecin analogue. Proc. Am. Assoc. Cancer Res. 33: 266, 1992 (Abstr.) .
62) Gupta E, Lestingi TM, Mick R, et al: Metabolic fate of irinotecan in humans: Correlation of glucuronidation with diarrhea. Cancer Res. 54: 3723 3725, 1994.
64) Rivory LP, Haaz M C, Canal P, et al: Pharmacokinetic interrelationships of irinotecan (CPT-11) and its three major plasma metabolites in patients enrolled in phase I/II trials. Clin. Cancer Res. 3: 1261 1266, 1997.
65) Johnson RK, McCabe FL, Faucette LF, et al: SK & F 104864, a water soluble analog of camptothecin with broad spectrum activity in preclinical models. Proc. Am. Assoc. Cancer Res. 30: 623, 1989 (Abstr.) .
69) Hendricks CB, Rowinsky EK, Grochow LB, et al: Effect of P glycoprotein expression on the accumulation and cytotoxicity of topotecan (SK & F 104864) , anew camptothecin analogue. Cancer Res. 52: 2268 2278, 1992.
72) Haas NB, LaCreta FP, Walczak J, et al: Phase I/pharmacokinetic study of topotecan by 24 hour continuous infusion weekly. Cancer Res. 54: 1220 1226, 1994.
73) ten Bokkel Huinink WW, Rodenhius S, Beijnen J, et al: Phase I study of the topoisomerase I inhibitor topotecan (SK & F 104864 A) . Proc. Am. Soc. Clin. Oncol. 11: 110, 1992 (Abstr.) .
74) Eckardt J, Burris H, Kuhn J, et al: Phase I and pharmacokinetic trial of continuous infusion topotecan in patients with refractory solid tumors. Proc. Am. Soc. Clin. Oncol. 11: 138, 1992 (Abstr.) .
75) Sirott MN, Saltz L, Young C, et al: Phase I and clinical pharmacologic study of intravenous topotecan (T) . Proc. Am. Soc. Clin. Oncol. 10: 104, 1991 (Abstr.) .
77) Rowinsky E, Sartorius S, Grochow L, et al: Phase I and pharmacologic study of topotecan, an inhibitor of topoisomerase I, with granulocyte colony stimulating factor (G CSF) : toxicologic differences between concurrent and post treatment G CSF administration. Proc. Am. Soc. Clin. Oncol. 11: 116, 1992 (Abstr.) .
83) Carmichael J, Gordon A, Malfetano J, et al: Topotecan, a new active drug, vs paclitaxel in advanced epithelial ovarian carcinoma: International Topotecan Study Group Trial. Proc. Am. Soc. Clin. Oncol. 15: 283, 1996 (Abstr.) .
84) Gordon A, Bookman M, Malmstrom H, et al: Efficacy of topotecan in advanced epithelial ovarian cancer after failure of platinum and paclitaxel: International Topotecan Study Group Trial. Proc. Am. Soc. Clin. Oncol. 15: 282, 1996 (Abstr.) .
90) Potmesil M, Hsiang YH, Liu LF, et al: Resistance of human leukemic and normal lymphocytes to drug induced DNA cleavage and low levels of DNA topoisomerase II. Cancer Res. 48: 3537 3543, 1988.
92) Cersosimo RJ: Idarubicin: An anthracycline antineoplastic agent. Clin. Pharm. 11: 152 167, 1992.
93) Stewart CF, Ratain MJ: Topoisomerase interactive agents. In Cancer: Principles and Practice of Oncology (eds. by Devita VT Jr, Hellman S, Rosenberg SA.) , 5th Edition, JB Lippincott, Philadelphia, 1997, pp. 452 469.
95) Praga C, Beretta G, Vigo PL, et al: Adriamycin cardiotoxicity: Asurvey of 1273 patients. Cancer Treat. Rep. 63: 827 834, 1979.
96) Bristow MR, Billingham ME, Mason JW, et al: Clinical spectrum of anthracycline antibiotic cardiotoxicity. Cancer Treat. Rep. 6: 873 879, 1978.
98) Weiss AJ, Metter GE, Fletcher WS: Studies on adriamycin using a weekly regimen demonstrating its clinical effectiveness and lack of cardiac toxicity. Cancer Treat. Rep. 60: 813 822, 1976.
104) Pratt CB, Ransom JL, Evans WE: Age related adriamycin cardiotoxicity in children. Cancer Treat. Rep. 62:
105) 1381 1385, 1978.
106) Juret P, Heron JF, Couette JE, et al: Hydroxy 9 methyl 2 ellipticinium for osseous metastases from breast cancer: A5 year experience. Cancer Treat. Rep. 66: 1909 1916, 1982.
107) Rouesse JG, Le Chevalier T, Caile P, et al: Phase II study of elliptinium in advanced breast cancer. Cancer Treat. Rep. 69: 707 708, 1985.
109) Grove WR, Fortner CL, Wiernik PH: Review of amsacrine, an investigational antineoplastic agent. Clin. Pharm. 1: 320 326, 1982.
114) Clark PI: Clinical pharmacology and schedule dependency of the podophyllotoxin derivatives. Semin. Onco1. 19: 20 27, 1992 (Suppl.) .
115) Joel SP, Hall M, Gaver RC, et al: Complete recovery of radioactivity after administration of 14C etoposide in man. Proc. Am. Soc. Clin. Oncol. 14: 168, 1995 (Abstr.) .
P.650 掲載の参考文献
3) Jackson DV, Bender RA: Cytotoxic thresholds of vincristine in a murine and human leukemia cell line in vitro. Cancer Res. 39: 4346 4349, 1979.
6) Houghton JA, Houghton PJ, Hazelton BJ, et al: In sitza selection of a human rhabdomyosarcoma resistant to vincristine with altered β-tubulins. Cancer Res. 45: 2706 2712, 1985.
9) Johnson IS, Armstrong JG, Gorman M, et al: The vinca alkaloids: anew class of oncolytic agents. Cancer Res. 23: 1390 1427, 1963.
11) Owellen RJ, Harte CA, Hains FO: Pharmacokinetics and metabolism of vinblastine in humans. Cancer Res. 37: 2597 2602, 1977.
12) Owellen RJ, Root MA, Hains FO: Pharmacokinetics of vindesine and vincristine in humans. Cancer Res. 37: 2603 2607, 1977.
13) Rahmani R, Bruno R, 11iadis A, et al: Clinical pharmacokinetics of the antitumor drug navelbine (5 ' noranhydrovinblastine) . Cancer Res. 47: 5796 5799, 1987.
14) Sethi VS, Jackson DV Jr, White DR, et al: Pharmacokinetics of vincristine sulfate in adult cancer patients. Cancer Res. 41: 3551 3555, 1981.
16) Ohnuma T, Norton L, Andrejczuk A, et al: Pharmacokinetics of vindesine given as an intravenous bolus and 24 hour infusion in humans. Cancer Res. 45: 464 469, 1985.
21) Zhou Pan XR, Sere6 E, Zhou XJ, et al: Involvement of human liver cytochrome P 4503Ain vinblastine metabolism: drug interactions. Cancer Res. 53: 5121-5126, 1993.
24) Sulkes A, Collins JM: Reappraisal of some dosage adjustment guidelines. Cancer Treat. Rep. 71: 229-133, 1987.
25) Owellen RJ, Hartke CA: The pharmacokinetics of 4 acetyl tritium vinblastine in two patients. Cancer Res. 35: 975 980, 1975.
29) Jehl F, Quoix E, Leveque D, et al: Pharmacokinetic and preliminary metabolic fate of navelbine I humans as determined by high performance liquid chromatography. Cancer Res. 51: 2073 2076, 1991.
34) Dorr RT, Alberts DS: Vinca alkaloid skin toxicity: antidote and drug disposition studies in the mouse. J. Natl. Cancer Inst. 74: 113 120, 1985.
39) Donaldson KL, Gollsby G, Kiener PA, et al: Activation of p 34cdk2 coincident with Taxol induced apoptosis. Cell Growth Differ. 5: 1041 1050, 1994.
40) Bissery M G, Guenard D, Gueritte Vogelein F, et al: Experimental antitumor activity of Taxotere (RP 56976, NSC 628503) , aTaxol analogue. Cancer Res. 51: 4845 4852, 1991.
42) Chervinsky D, Brecher M, Hoelcle M: Cremophor EL enhances taxol efficacy in a multi drug resistant C 1300 neuroblastoma cell line. Anticancer Res. 13: 93 96, 1993.
43) Longnecker SM, Donehower RC, Cates AE, et al: High performance liquid chromatographic assay for taxol in human plasma and urine and pharmacokinetics in a phase I trial. Cancer Treat. Rep. 71: 53 59, 1987.
44) Wiernik PH, Schwartz EL, Strauman JJ, et al: Phase I clinical and pharmacokinetic study of taxol. Cancer Res. 47: 2486 2493, 1987.
50) Sparreboom A, van Tellingen O, Nooijen WJ, et al: Nonlinear pharmacokinetics of paclitaxel in mice results from the pharmaceutical vehicle Cremophor EL. Cancer Res. 56: 2112 2115, 1996.
52) Harris JW, Rahman A, Kim BR, et al: Metabolism of taxol by human hepatic microzomes and liver slices participation of cytochrome P4503A4 and an unknown p 450 enzyme. Cancer Res. 54: 4026 4035, 1994.
53) Cresteil T, Monsarrat B, Alvinerie P, et al: Taxol metabolism by human liver microsomes: identification of cytochrome P450 isozymes involved in its biotransformation. Cancer Res. 54: 386 392, 1994.
54) Rahman A, Korzekwa KR, Grogan J, et al: Selective biotransformation of taxol to 6 a hydroxytaxol by human cytochrome P4502C8. Cancer Res. 54: 5543 5546, 1994.
57) LeBlanc GA, Sundseth SS, Weber GF, et al: Platinum anticancer drugs modulate P 450 mRNA levels and differentially alter hepatic drug and steroid hormone metabolism in male and female rats. Cancer Res. 52: 540-547, 1992.
60) Gianni L, ViganδL, Locatelli A, et al: Human pharmacokinetic characterization and in vitro study of the interaction between doxorubicin and paclitaxel in patients with breast cancer. J. Clin. Oncol. 15: 1906-1915, 1997.
70) Extra JM, Rousseau F, Bruno R, et al: Phase I and pharmacokinetic study of taxotere (RP 56976;NSC 628503) given as a short intravenous infusion. Cancer Res. 53: 1037 1042, 1993.
72) Bissett D, Setanoians A, Cassidy J, et al: Phase I and pharmacokinetic study of taxotere (RP 56976) administered as a 24 hour infusion. Cancer Res. 53: 523 527, 1993.
73) De Valeriola D, Brassine C, Piccart M, et al: Study of excretion balance, metabolism and protein binding of C 14 radiolabelled taxotere (RP 56976, NSC 6285039) in cancer patients. Proc. Am. Assoc. Cancer Res. 34: 373, 1993.
74) Marre F, Sanderink GJ, de Sousa G, et al: Hepatic biotransformation of docetaxel (Taxotere) in vitro: involvement of the CYP 3A subfamily in humans. Cancer Res. 56: 1296 1302, 1996.
76) Francis P, Bruno R, Seidman A, et al: Pharmacodynamics of docetaxel (taxotere) in patients with liver metastases. Proc. Am. Soc. Clin. Oncol. 13: 138, 1994.
78) Donehower RC, Rowinsky EK, Grochow LB, et al: Phase I trial of taxol in patients with advanced cancer. Cancer Treat. Rep. 71: 1171 1177, 1987.
82) Grem JL, Tutsch KD, Simon KJ, et al: Phase I study of taxol administered as a short iv infusion daily for 5 days. Cancer Treat. Rep. 71: 1179. 1184, 1987.
84) Ohtsu T, Sasaki Y, Tamura T, et al: Clinical pharmacokinetics and pharmacodynamics of paclitaxel: a 3 hour infusion versus a 24 hour infusion. Clin. Cancer Res. 1: 599 606, 1995.
86) Arbuck SG, Christian MC, Fisherman JS, et al: Clinical development of Taxol. Monogr. Natl. Cancer Inst. 15: 11 24, 1993.
87) Lubejko BG, Sartorius SE: Nursing considerations in paclitaxel (Taxol) administration. Semin. Oncol. 20 (suppl. 3) : 26 30, 1993.
89) Arbuck SG, Strauss H, Rowinsky E, et al: Areassessment of cardiac toxicity associated with taxol. Monogr. Natl. Cancer Inst. 15: 117 130, 1993.
94) Aapro MS, Zulian G, Alberto P, et al: Phase I and pharmacokinetic study of RP 56976 in a new ethanol free formulation of Taxotere. Ann. Onco1. 3 (suppl. 5) : 53, 1992.
99) Onetto N, Canetta R, Winograd B, et al: Overview of taxol safety. Monogr. Natl. Cancer Inst. 15: 131 139, 1993.
P.658 掲載の参考文献
3) Asou N, Adachi K, Tamura J, et al: Analysis of prognostic factors in newly diagnosed acute promyelocytic leukemia treated with al1 trans retinoic acid. J. Clin. Oncol. 1997, (in press) .
7) Muindi JR, Frankel SR, Huselton C, et al: Clinical pharmacology of oral all trans retinoic acid in patients with acute promyelocytic leukemia. Cancer Res. 52: 2138 2142, 1992.
8) Usuki K, Endo M, Osawa M, et al: Pharmacokinetics of all trans retinoic acid in Japanese patients with acute promyelocytic leukemia. Int. J. Hematol. 63: 19 23, 1996.
9) Adamson PC: Pharmacokinetics of all trans retinoic acid: Clinical implication in acute promyelocytic leukemia. Semin. HematoL 31: 14 17, 1994.
P.667 掲載の参考文献
7) Cheson BD: Miscellaneous chemotherapeutic agents. In: Cancer: Principles and Practice of Oncology (eds. by De Vita VT Jr, Hellman S, Rosenberg SA) . 5th Edition, JB Lippincott, Philadelphia, 1997, pp. 490 498.
8) Worton KS, Kerbel RS, Andrulis IL: Hypomethylation and reactivation of the asparagine synthetase gene induced by L asparaginase and ethyl methanesulfonate. Cancer Res. 51: 985 989, 1991.
10) Ohnuma T, Holland JF, Sinks LF: Biochemical and pharmacological studies with L-asparaginase in man. Cancer Res. 30: 2297 2305, 1970.
11) 藤本孟男: 小児白血病・リンパ腫, 臨床腫瘍学 (日本臨床腫瘍研究会編) , 癌と化学療法, 東京, 1996, pp. 993-1012.
13) Castaman G, Rodeghiero F, Dini E: Thrombotic complications during L asparaginase treatment for acute lymphocytic leukemia. Haematologica 75: 567 569, 1990.
19) Barlogie B, Drewinko B, Schumann J, et al: Pulse cytophotometric analysis of cell cycle perturbation with bleomycin in vitro. Cancer Res. 36: 1182 1187, 1976.
20) Chabner BA, Myers CE: Antitumor antibiotics. In: Cancer: Principles and Practice of Oncology (eds. by De Vita VT Jr, Hellman S, Rosenberg SA) . 4th Edition, JB Lippincott, Philadelphia, 1993, pp. 374 384.
30) Teicher BA: Antitumor alkylating agents. In: Cancer: Principles and Practice of Oncology (eds. by De Vita VT Jr, Hellman S, Rosenberg SA) . 5th Edition, JB Lippincott, Philadelphia, 1997, pp. 405 418.
31) Keyes SR, Fracasso PM, Heimbrook DC, et al: Role of NADPH: cytochrome C reductase and DT disphorase in the biotransformation of mitomycin C. Cancer Res. 44: 5638 5643, 1984.
33) Van Hazel GA, Scott M, Rubin J: Pharmacokinetics of mitomycin C in patients receiving the drug alone or in combination. Cancer Treat. Rep. 67: 805 810, 1983.
41) Erei E 3d: The clinical use of actinomycin. Cancer Chemother. Rep. 58: 49 54, 1974.
45) Stewart CF, Ratain MJ: Topoisomerase interactive agents. In: Cancer: Principles and Practice of Oncology (eds. by De Vita VT Jr, Hellman S, Rosenberg SA) . 5th Edition, JB Lippincott, Philadelphia, 1997, pp. 452 467.
47) Chabner BA: Miscellaneous agents. In: Cancer: Principles and Practice of Oncology (eds. by De Vita VT Jr, Hellman S, Rosenberg SA) . 4th Edition, JB Lippincott, Philadelphia, 1993, pp. 385 389.
51) Yap BS, Baker LH, Sinkovic JG, et al: Cyclophosphamide, vincristine, adriamycin, and DTIC (CYVADIC) combination chemotherapy for the treatment of advanced sarcomas. Cancer Treat. Rep. 64: 93 98, 1980.
52) Comis RL: DTIC (NSC 45388) in malignant melanoma: aperspective. Cancer Treat. Rep. 60: 165 176, 1976.
53) Feaux de Lacroix W, Runne U, Hauk H, et al: Acute liver dystrophy with thrombosis of hepatic veins: afatal complication of dacarbazine treatment. Cancer Treat. Rep. 67: 779 784, 1983.
55) Smith PJ, Ekert H, Waters KD, et al: High incidence of cardiomyopathy in children treated with Adriamycin and DTIC i combination chemotherapy. Cancer Treat. Rep. 61: 1736 1738, 1977.
58) Therman E: Chromosome breakage by 1 methyl 2 benzylhydrazine in mouse cancer cells. Cancer Res. 32: 1133 1136, 1972.
60) Chabner BA, Sponzo R, Hubbard S, et al: High dose intermittent intravenous infusion of procarbazine. Cancer Chemother. Rep. 57: 361 363, 1973.
62) Weiss RB: Introduction: new sources and new antitumor drugs in development. Semin. Oncol. 24: 153 155, 1997.
63) Christian MC, Pluda JM, Ho PTC, et al: Promising new agents under development by the division of cancer treatment, diagnosis, and centers of the National Cancer Institute. Semin. Oncol. 24: 219 240, 1997.
73) Akinaga S, Gomi K, Morimoto M, et al: Antitumor activity of UCN 01, a selective inhibitor of protein kinase C, in murine and human tumor models. Cancer Res. 51: 4888 4892, 1991.
75) Arguello F, Alexander M, Sterry JA, et al: Flavopiridol induces apoptosis of normal lymphoid cells, causes immunosuppression, and has potent antitumor activity in vito against human leukemia and lymphoma xenografts. Blood 91: 2482 2490, 1988.
76) Bible KC and Kaufmann SH.: Flavopiridol: acytotoxid flavone that induces cell death in noncycling A549human lung carcinoma cells. Cancer Res. 56: 4856 4861, 1996.
77) Carlson BA, Dubay MM, Sausville EA, et al.: Flavopiridol induces Gl arrest with inhibition of cyclin dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells. Cancer Res 56: 2973 2978, 1996.
80) Thomas J, Tutsch K, Arzoomanian R, et al: Phase I clinical and pharmacokinetic trial of the cyclin dependent kinase (CDK) inhibitor flavopiridol. Proc. Am. Soci. Clin. Oncol. 17: 209a, 1998.
81) Werner JL, Kelsen DP, Karpeh M, et al: The cyclin dependent kinase inhibitor flavopiridol is an active and unexpectedly toxic agent in advanced gastric cancer. Proc. Am. Soci. Clin. Oncol. 17: 234a, 1998.
82) Schwartz GK, Werner JL, Maslak P, et al: Flavopiridol enhances the biological effects of paclitaxel: aphase Itrial in patients with advanced solid tumors. Proc. Am. Soci. Clin. Oncol. 17: 188a, 1998.
87) Kohn EC, Sandeen MA, Liotta LA: ln vivo efficacy of a novel inhibitor of selected signal transduction pathways including calcium, arachidonate, and inositol phosphates. Cancer Res. 52: 3208 3212, 1992.
89) Figg WD, Cole KA, Reed E, et al: Pharmacokinetics of orally administered carboxyamidotiazole, an inhibitor of calcium mediated signal transduction. Clin. Cancer Res. 1: 797 803, 1995.
90) Kohn EC, Reed E, Sarosy G, et al: Clinical investigation of a cytostatic calcium influx inhibitor in patients with refractory cancers. Cancer Res. 56: 569 573, 1996.
91) Pluda JM: Tumor associated angiogenesis: mechanisms, clinica川mplications, and therapeutic strategies. Semin. Oncol. 24: 203 218, 1997.
95) Carmichael J, Ledermann JA, Woll PJ, et al: Phase IB study of concurrent administration of marimastat and gemcitabine in non resectable pancreatic cancer. Proc. Am. Soc. Clin. Oncol. 17: 232a, 1998.
96) Gradishar W, Sparano J, Cobeigh M, et al: Aphase I study of marimastat in combination with doxorubicin and cyclophosphamide in patients with metastatic breast cancer. Proc. Am. Soc. Clin. Oncol. 17: 144a, 1998.
97) O'Reilly S, Mani S, Ratain MJ, et al: Schedules of 5FU and the matrix metalloproteinase inhibitor marimastat (MAR) : aphase I study. Proc. Am. Soc. Clin. Oncol. 17: 217a, 1998.
104) Sim BKL, O'Reilly MS, Liang H, et al: Arecombinant human angiostatin protein inhibits experimental primary and metastatic cancer. Cancer Res. 57: 1329 1334, 1997.
108) Dorie MJ and Brown JM.: Tumor specific, schedule dependent interaction between tirapazamine (SR4233) and cisplatin. Cancer Res. 53: 4633 4636, 1993.
109) Senan S, Rampling R, Graham MA, et al: Phase I and pharmacokinetic study of tirapazamine (SR4233) administered every three weeks. Clin. Cancer Res. 3: 31 38, 1997.
111) Curran WJ, Movsas B, Hancock S, et al: Phase I trial of oral TirazoneTM (tirapazamine, TPZ) shows good bioavailability and tolerance. Proc. Am. Soci. Clin. Oncol. 17: 208a, 1998.
112) Von Pawel J and Von Roemeling R.: Survival benefit from TirazoneTM (tirapazamine) and cisplatin in advanced non-small-cell lung cancer (NSCLC) patients: final results from the international phase III catapul I trial. Proc. Am. Soci. Clin. Oncol. 17: 454a, 1998.
113) Kim C, Pinto HA, Tate D, et al: Tirapazamine, cisplatin & fluorouracil as induction chemotherapy & simultaneous chemoradiotherapy for organ preservation in advanced head and neck cancer. Proc. Am. Soci. Clin. Oncol. 17: 395a, 1998.
114) Aghajanian C, Levenbeck C, Chen Y, et al: Amulti center phase II study of tirapazamine plus cisplatin in patients with metastatic or recurrent cervical cancer. Proc. Am, Soci. Clin. Oncol. 17: 353a, 1998.
115) Gatineau M, Rixe O, Fizazi L, et al : PhaseI study of tirapazamine cisplatin vinorelbine in patients with inoperable non-small-cell lung cancer (NSCLC) . Proc. Am. Soci. Clin. Oncol. 17: 485a, 1998.
116) Ho PTC, Parkinson DR: Antisense oligonucleotides as therapeutics for malignant diseases. Semin. Oncol. 24: 187 202, 1997.
122) Bergsland E, Mani S, Kirn D, et al: Intratumoral injection of ONYX 015 for gastrointestinal tumors metastatic to the liver: aphase I trial. Proc. Am. Soci. Clin. Oncol. 17: 211a, 1998.
123) Mulvihill SJ, Warren RS, Fell S, et al: Aphase I trial of intratumoral injection with an EIB attenuated adenovirus, ONYX 015, into unresectable carcinomas of the exocrine pancreas. Proc. Am. Soci. Clin. Oncol. 17: 211a, 1998.
124) Kirn D, Nemunaitis J, Ganly I, et al: Aphase II trial of intratumoral injection with an EIB deleted adenovirus, ONYX 015, in patients with recurrent, refractory head and neck cancer. Proc. Am. Soci. Clin. Oncol. 17: 391a, 1998.
P.687 掲載の参考文献
2) Dewhirst NW: Angiogenesis and blood flow in solid tumors. In: Drug resistance in oncology (ed by Teicher BA) . Marcel Dekker, New York, 1993, pp. 3 24.
13) Tsuruo T, Iida H, Tsukagoshi S, et al: Overcoming of vincristine resistance in P 3881eukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil. Cancer Res. 41: 1967 1972, 1981.
14) Beck WT, Dalton WS: Mechanisms of drug resistance. In: Cancer: Principles & Practice of Oncology (eds by Devita Jr, Hellman S, Rosenberg SA) . 5th Edition, Lippincott Raven, Philadelphia, 1997, pp. 498 512.
16) Jedlitschky G, Leier I, Bucholz U, et al: Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene encoded conjugate export pump. Cancer Res. 56: 988, 1996.
20) Scheper RJ, Broxtermam HJ, Scheffer GL, et al: Overexpression of a Mr 110, 000 vesicular protein in non Pglycoprotein mediated multidrug resistance. Cancer Res. 53: 1475 1479, 1993.
24) Izquierdo MA, Scheffer GL, Flens MJ, et al: Broad distribution of the multidrug resistance related vault lung resistance protein in normal human tissues and tumors. Am. J. Pathol. 148: 877 887, 1996.
28) 西條長宏: シスプラチン耐性. 薬剤耐性の分子機構 (鶴尾 隆編) , 羊土社, 東京, 1994, pp. 109-121.
31) Taniguchi K, Wada M, Kohno K, et al: Ahuman canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin resistant human cancer cell lines with decreased drug accumulation. Cancer Res. 56: 4124 4129, 1996.
32) Masuda H, Ozols RF, Lai G M, et al: Increased DNA repair as a mechanism of acquired resistance to cisdiamminedichloroplatinum (II) in human ovarian cancer cell lines. Cancer Res. 48: 5731, 1988.
34) Masuda H, Tanaka T, Matsuda H, et al: Increased removal of DNA bound platinum in a human ovarian cancer cell line resistant to cis diamminedichloroplatinum (II) . Cancer Res. 50: 1863, 1990.
42) Johnson SW, Swiggard PA, Handel LM, et al: Relationship between platinum DNA adduct formation and removal and cisplatin cytotoxicity in cisplatin sensitive and resistant human ovarian cancer cells. Cancer Res. 54: 5911, 1994.
43) Hamaguchi K, Godwin AK, Yakushiji M, et al: Cross resistance to diverse drugs is associated with primary cisplatin resistance to ovarian cancer cell lines. Cancer Res. 54: 5911, 1994.
45) Mamenta EL, Poma EE, Kaufmann WK, et al: Enhanced replicative bypass of platinum DNA adducts in cisplatin resistant human ovarian carcinoma cell lines. Cancer Res. 54: 3500, 1994.
46) 秋山伸一: 抗がん剤のはたらき-課題と展望-. 共立出版, 東京, 1991.
48) Wang F S, Aschele C, Sobrero A, et al: Decreased folypolyglutamate synthetase expression: anovel mechanism of fluorouracil resistance. Cancer Res. 53: 3677, 1993.
49) Berger SH, Jenh C H, Jonson LF, et al: Thymidylate synthase overproduction and gene amplification in fluorodeoxyuridine resistant human cells. Mol. Pharmacol. 28: 461, 1985.
50) Barbour KW, Berger SH, Berger FG: Single amino acid substitution defines a naturally occurring genetic variant of human thymidylate synthase. Mol. Pharmacol. 37: 515, 1990.
P.719 掲載の参考文献
1) Leventhal BG, Wittes RE: Research Methods in Clinical Oncology. Raven Press, New York, 1986.
3) 西條長宏: がん治療の進歩と臨床試験. からだの科学 187: 74-78, 1996.
4) Kisner DL: Reporting treatment toxicities. In Cancer Clinical Trials: Methods and Practice, edited by ME Buyse, MJ Staquet, RJ Sylvester, Oxford University Press, Oxford, 1984, pp. 178 190.
7) Japan Society for Cancer Therapy: Criteria for the evaluation of the clinical effects solid cancer chemotherapy. J. Jpn. Soc. Cancer Ther. 28: 101 130, 1993.
14) 江口研二, 栗原 稔, 下妻晃二郎・他: がん薬物療法におけるQOL調査票. 日癌治療会誌28 (8) : 1140-1144, 1993.
15) Alley MC, Scudiero DA, Monks Hursey ML, et al: Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay. Cancer Res. 48: 589 601, 1988.
16) 抗悪性腫瘍薬の臨床評価ガイドライン作成に関する研究班: 抗悪性腫瘍の臨床評価方法に関するガイドライン.
17) Freireich EJ, Gehan EA, Rall DP, et al: Quantitative comparision of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man. Cancer Chemother. Res. 50: 219 244, 1966.
20) Collins JM, Zaharko DS, Dedrick RL, et al: Potential roles for pharmacology in phase I clinical trials. Cancer Treat. Rep. 70: 73 80, 1986.
22) Bisset D, Graham MA, Setanoians A, et al: Phase I and pharmacokinetic study of Rizoxin. Cancer Res. 52: 2894 2898, 1992.
26) Ohtsu T, Sasaki Y, Tamura T, et al: Clinical pharmacokinetics and pharmacodynamics of paclitaxel: A3 hour infusion versus a 24 hour infusion. Clin. Cancer Res. 1: 599 606, 1995.
28) Rubin P, Keys H, Salazar O: New designs for radiation oncology research in clinical trials. Seminars inOncology 8 (4) : 453, 1981.
29) Estey E, Hoth D, Simon R, et al: Therapeutic response in Phase I trials of anti neoplastic agents. Cancer Treat. Rep. 70: 1105 1115.
36) Radice PA, Bunn PA Jr, Ihde DC: Therapeutic trials with VP 16 213 and VM 26: Active agents in small cell lung cancer, non Hodgkin 's lymphomas and other malignancies. Cancer Treat. Rep. 63: 1231 1239, 1979.
37) 下山正徳, 富永祐民, 西條長宏・他: 臨床試験計画 (プロトコール) の作成と実施, 並びに結果の統計解析とその評価について. 癌の臨床36: 2503-2525, 1990.
40) Ettinger DS, Finkelstein D, Ritch P, et al: Randomized trial of single agents VS combination chemotherapy in extensive stage small cell lung cancer. Proc. ASCO l1: 295, 1992.
41) Stephan KC: Clinical aspects in the design and conduct of phase II trials. Cancer Clinical Trials.: 224 238, 1988.
43) Gehan EA, Schneiderman MA: Experimental design of clinical trials. In Cancer Medicine, edited by JF Holland, E, Frei III, 2nd ed. Lea and Febiger, Philadelphia, 1982, pp. 531 553.
47) Moertel CG, Thynne GS: Large bowel. In Cancer Medicine, edited by JF Hollandd, E Frei III, 2nd ed. Lea andFebiger, Philadelphia, 1982, pp. 1830 1859.
48) Simon R, Wittes RE, Ellenberg SS: Randomized phase II clinical trials. Cancer Treat. Rep. 69: 1375 1381, 1985.
52) Aisner J. Alverto P, Bitran J, et al: Role of chemotherapy in small cell lung cancer: Aconsensus report of the Internaional Association for the study of Lung cancer Workshop. Cancer Treat. Rep. 67: 37 43, 1983.
53) Tannock I: Reading the literature with a clinical eye. ASCO Education Book, 1992. pp. 114 117.
54) Tannock I: New perspective in combined radio therapy and chemotherapy treatment. IInd IASLC Workshop Inagural Conference: 1 39, 1992.
65) 下山正徳, 田島絹子, 恒松隆一郎・他: 厚生省がん研究助成金指定研究「固形がんの集学的治療の研究」班における臨床試験計画 (プロトコール) の作成と実施, 並びに結果の統計解析とその評価に関するガイドライン (改訂第3版) 第I部: プロトコールの作成に関する医学的並びに科学的事項とその審査. 癌の臨床 42: 197-229, 1996.
66) Simon RM: Design and conduct of clinical trials. In Cancer: Principles and Practice of Oncology, edited by VT DeVita Jr, S Hellman, SA Rosenberg, 1st ed, Lippincott, Philadelphia, 1982, pp. 198 225.
67) George SL: The required size and length of a phase III clinical trial. In Cancer Clinical Trials: Methods and Practice, edited by ME Buyse, MJ Staquet, RJ Sylvester, Oxford University Press, Oxford, 1984, pp. 287 310.
80) O'Brien PC, Fleming TR: Amultiple testing procedure for clinical trials. Biometrics 351549 556, 1979.
82) Wittes RE, Goldin A: Unresolved issues in combination chemotherapy. Cancer Treat. Rep. 70: 105 125, 1986.
83) Leyland Jones B, O'Dwyer PJ: Biochemical modulation. Application of laboratory models to the clinic. Cancer Treat. Rep. 70: 219 230, 1986.
84) Martin DS, Stolfi RL, Sawyer RC, et al : Application of biochemical modulation with a therapeutically inactive modulating agent in clinical trials of cancer chemotherapy. Cancer Treat. Rep. 69: 421 423, 1985.
86) Schellens JH, Ma J, Bruno R, et al: Pharmacokinetics of cisplatin and Taxotere (docetaxel) and WBC DNA adduct formation of cisplatin in the sequence Taxotere/cisplatin and cisplatin/Taxotere in a Phase I/II study in solid tumor patients. Proc. ASCO 131323, 1994.
94) 佐久間昭: 医学統計 Q&A. 金原出版, 東京, 1987.
95) Pocock SJ: Clinical trials: a practical approach. John Wiley & Sons, Chichester, 1983.
96) 厚生省医薬安全局GCP研究会監修: 改訂GCPハンドブック. 薬業時報社, 東京, 1997.
P.738 掲載の参考文献
3) Appelbaum, PS, Lidz CW, Meisel A: インフォームド・コンセント (杉山弘行訳) . 文光堂, 東京, 1994.
4) Faden RR, Beauchamp TL: A history and theory of informed consent. Oxford University Press, NY, 1986. (酒井忠昭, 秦浄一訳: インフォームド・コンセント-患者の選択, みすず書房, 1994.)
5) Pocok SJ: クリニカルトライアル (コントローラー委員会監訳) . 篠原出版, 東京, 1989.
6) 砂原茂一: 臨床医学研究序説 方法論と倫理. 医学書院, 東京, 1988.
7) 田沢公樹, 中島宏昭, 石原潤一・他: わが国の肺癌化学療法におけるinformed consent全国アンケート調査. J. Jpn. Soc. Cancer Ther. 21: 2454-2459, 1986.
8) 篠田雅幸, 江口研二, 大田恵一朗・他: 癌臨床試験でのインフォームド・コンセントに対する医師の認識度のアンケート調査. 日癌会総会記 633, 1994.
9) 久保昭仁, 中川和彦, 宮本裕介・他: 肺癌患者におけるinformed consent: 大阪市立羽曳野病院第2内科における現状. J. Jpn. Soc. Cancer. Ther. 30: 664-679, 1995.
10) The Neuremberg Code, Ethics in Medicine: Historical perspectives and contemporary concerns. (Reiser SJ, Dyck AJ, Curren WJ. eds.) M. 1. T. Press, Cambridge, Mass., 1977, pp. 272 273.
11) Declaration of Helsinki: Recommendations guiding medical doctors in biochemical research involving human subjects. (光石忠敬訳: ヘルシンキ宣言: 世界医師会総会, ヘルシンキ1964, 東京1975, ベニス1983, ホンコン1989, 改訂版. 臨床評価 22: 289-291, 1994.)
12) The Council for International Organizations of Medical Sciences (CIOMS) in collaboration with the World Health Organization (WHO) , International ethical guidelines for biomedical research involving human subjects, Geneva, 1993. (光石忠敬訳: 国際医科学評議会 (世界保健機関協力) , 被験者に対する生物医学研究についての国際的倫理指針 (1993年ジュネーブ) . 臨床評価 22: 261-288, 1994.)
13) The Council for International Organizations of Medical Sciences (CIOMS) , International guidelines for ethical review of epidemiological studies, Geneva, 1991. (光石忠敬訳: 国際医科学評議会, 疫学研究の倫理審査のための国際的指針 (1991年ジュネーブ) . 臨床評価20: 563-578, 1992.)
14) President 's Commission for the study of ethical problems in medicine at biochemical and behavioral research: Final report on studies of the ethical and legal problems in medicine and biomedical and behavioral research- summing up-, 1993. (医務局医事課監訳, 牛場大蔵・他訳: アメリカ大統領委員会, 生命倫理総括レポート. 篠原出版, 1984.)
15) 加藤尚武: 環境倫理学のすすめ (丸善ライブラリー032) . 丸善, 東京, 1991, pp. 1-226.
16) 日本医師会生命倫理懇談会報告: 説明と同意についての報告. 日本医事新報 3430: 109-112, 3431: 112-113, 3432: 118-119, 平成2年1月, 2月.
17) 星野一正: 医療の倫理 (岩波新書201) . 岩波書店, 東京, 1991.
18) 光石忠敬: 共同作業への参加の証としてのインフォームド・コンセント. 臨床評価 16: 569-580, 1988.
19) GCPハンドブック: 医薬品の臨床試験の実施に関する基準. 厚生省薬務局審査第一課監修, 薬業時報社, 東京, 平成2年.
20) International conference on harmonization of technical requirements for registration of pharmaceuticals for human use-Guideline for good clinical practice-ICH expert working group, ICH Steering Committee IFPMA, Geneva May, 1995. (医薬品の臨床試験の実施に関する基準 (GCP) のガイドライン (案) : 平成7年7月厚生省薬務 局審査課. 臨床評価 23: 369-484, 1995.)
21) 厚生省令第28号, 薬務局長通知430号, 審査課長通知445号, 安全課長通知68号: 新GCP関連資料集. 日本製薬工 業会医薬品評価委員会編 ミクス, 東京, 1997, pp. 89-342.
22) 厚生省令10号: 平成9年3月10日.
23) 下山正徳, 江口研二, 恒松隆一郎・他: 臨床試験の作成と実施, ならびに結果の統計解析とその評価に関するガイドライン (改訂第3版) . 癌の臨床・篠原出版, 東京, 42: pp. 339-352, 1996.
24) OPRR Protecting Human Research Subjects: Institutional Review Board Guidebook. US Department of Health and Hurnan Services, Pubic Health Service, National Institute of Health, 1993.
25) 下山正徳: 抗悪性腫瘍薬臨床評価方法に関するガイドライン解説. 新薬臨床評価ガイドライン1994. 日本公定書協会編, 薬業日報社, 東京, 1994, pp. 358-377.
26) 島田安博: 進行胃癌グループのプロトコール研究におけるICの実態. 薬物療法を主体とする固形癌の集学的治療の臨床試験研究 (垣添忠生, 下山正徳監修) . 協和企画通信, 東京, 1991.
27) 柳田邦男編: 元気の出るインフォームド・コンセント. 中央法規, 東京, 1995.
30) 内藤周幸, 光石忠敬: 医学実験無作為化臨床試験の論理と倫理. 篠原出版, 東京, 1987.
31) Leventhal BG, Wittes RE: Research methods in clinical oncology. Raven Press, New York, 1988
33) 浜島信之: 無作為化割付臨床試験. 癌と化学療法社, 東京, 1993.
34) 小島大輔: 癌の告知について. 日医大誌 58: 39-49, 1991.
35) 佐藤郁世, 田沢公樹, 深浦麻人・他: 癌告知に関する意識調査-外来患者に対するアンケート調査-. J. Jpn. Soc. Cancer Ther. 29: 1677-1685, 1994.
36) 小林国彦, 川崎千佳, 矢島千歳・他: 肺癌患者における告知状況の解析. J. Jpn. Soc. Cancer Ther. 29: 1001-1009, 1994.
37) 日本消化器病学会倫理委員会: 医の倫理に関するアンケート調査結果の報告. 日消誌 90: 2775-2794, 1993.
38) 松栄達郎, 清水美登里, 吉田博子・他: がん死亡者の告知, 生活の質, 説明と同意. 厚生の指標 40: 19-27, 1993.
39) 毎日新聞世論調査部: 第10回『がん』に関する全国世論調査報告書. 1990年12月.
45) Kemp N, Skinner E, Toms J: Randomized clinical trials of cancer treatment a public opinion survey. Clin. Oncol. 10: 155 161, 1984.
49) 江口研二 兵頭一之介, 渡辺 亨・他: がん治療におけるインフォームドコンセントの在り方とそれに関連する諸問題の検討. 厚生省がん研究助成金による研究報告集平成5年度, 平成7年, pp. 456-460.
56) 浜島信之: 癌患者を対象とした市販後薬剤の無作為化比較試験. J. Jpn. Soc. Cancer Ther. 27: 1701-1706, 1992.
75) Olver IN, Turrell SJ, Olszewski NA, et al: The impact of a full disclosure information and consent form on patients receiving standard cytotoxic chemothrapy. Proc. ASCO 13: 14-71, 1994.
79) 芳賀敏彦: がんの治療と研究. メヂカルヒューマニティ 3: 15-21, 1988.
80) 上田慶二: 治験におけるGCPの現状と問題点. GCPはどう変わるのか厚生省GCP説明会. ミクス, 東京, 1996, pp. 60-78.
P.766 掲載の参考文献
1) 久繁哲徳: 臨床経済的評価の枠組み, その2. 保険診療 50 (10) : 21-28, 1995.
2) 厚生省大臣官房統計情報部: 平成8年度国民医療費. 厚生省統計協会, 東京, 1996.
6) 久繁哲徳: 医療システムの転換と経済的評価. 保険診療 50 (2) : 21-26, 1995.
7) Evans RG: Strained mercy. Butterworth, 1984.
8) 久繁哲徳: 医療のテクノロジー・アセスメント. 病院 52: 10-13, 1993.
9) 久繁哲徳: ベッドサイドの医療評価学, 1: せめて害以上の良い医療を. Cardiologist 1: 47-52, 1996.
13) 久繁哲徳: 臨床経済学のスタンス. 保険診療 50 (3) : 19-23, 1995.
14) Detsky AS: The economic foundation of national health policy. Ballinger Pub, Cambridge, 1978.
15) ドラモンドら (編著) : 久繁哲徳, 西村周三 (監訳) , 臨床経済学, 篠原出版, 東京, 1990.
16) 久繁哲徳: 臨床経済的評価の枠組み, その1. 保険診療 50 (9) : 21-26, 1995.
17) Gold MR, Siegel JE, Russell LB: Cost effectiveness in health and medicine. Oxford Univ Press, NY, 1996.
19) 久繁哲徳: 医薬品の経済的評価. 月刊薬事 38: 2921-2929, 1996.
20) 久繁哲徳: 経済的効率のリーグ表. 保険診療 51 (5) : 57-61, 1996
21) Laupacis A, Feeney D, Detsky AS, et al: How attractive does a new technology have to be to warrant adoption and utilization? Tentative guidelines for using clinical and economic evaluation. CMAJ 146: 473-481, 1992.
22) 久繁哲徳: 薬剤の経済的評価, 効果と効率から見た社会的利益. 医薬品研究 27: 215-234, 1996.
23) Scientific American: What you need to know about cancer. WH Freeman and Co, NY, 1996.
24) 久繁哲徳: 疾病予防対策の評価と実行に向けての合意形成, 成人病の二次予防と一次予防の効果をめぐって. 日本医事新報 3516: 48-52, 1991.
25) 久繁哲徳: 効果的・効率的医療の検討 (上・下) . 社会保険旬報 1751: 10-13, 1752: 16-21, 1992.
26) US Preventive Services Task Force: Guide to Clinical Preventive Services. William & Wilkins, 2 nd ed, New York, 1996.
36) Casicato DA, Lowitz BB (eds) : Manual of clinical oncology, 3rd ed, Lippincott Raven, Philadelphia, 1995.
37) Berger DH, Feig BW, Fuhrman GM: The M. D. Anderson surgical oncology handbook, Little Brown, NY, 1995.
40) 久繁哲徳, 片山貴文, 小池道子・他: 生活の質に基づく乳癌治療法選択の判断分析. 乳癌の臨床 12: 3-12, 1997.
41) 久繁哲徳: 早期乳癌治療のテクノロジー・アセスメント, わが国における医療テクノロジー・アセスメントの適用に関する研究. 平成8年度厚生科学研究報告書, 1997.
46) Dillman RO, Seagan SL, Herndon J, et al: Randomized trial of induction chemotherapy plus radiation therapyvs RT alone in stage III non-small-cell lung cancer. Proc. ASCO 12: 329, 1993.
50) 大野竜三: 白血病の診断, 治療. 第2版, 中外医学社, 東京, 1994.
51) Burt RK, Deeg HJ, Lothian ST, et al: On call in, bone marrow transplantation. Chapman Hill, NY, 1996.
52) 長尾 大: わが国における造血幹細胞移植の全国集計 (1993) . 今日の移植 7: 93-101, 1994.
53) United States General Accounting Office: Bone marrow transplantation, International comparisons of availability and appropriateness of use, 1994.
55) 久繁哲徳: 急性白血病に対する骨髄移植の経済的評価. 平成7年度厚生科学研究, 臓器技術臨床研究開発事業研究報告書, 1995.
58) 久繁哲徳, 片山貴文, 三笠洋明: 抗悪性腫瘍剤に起因する嘔吐のTropisetron (5-HT3受容体拮抗剤) による予防に関する経済的評価. 薬理と治療 25: 2203-2212, 1997.
P.773 掲載の参考文献
2) 開原成允: 総括班報告書. 遠隔医療に関する研究. 平成8年度厚生省情報技術開発研究事業研究成果報告書. 1996, pp. 1-23.
3) 山口直人: 診療支援システム. 遠隔医療に関する研究. 平成8年度厚生省情報技術開発研究事業研究成果報告書. 1996, pp. 85-162.
P.788 掲載の参考文献
1) 光石忠敬訳: 「被験者に対する生物医学研究についての国際的倫理指針」. 臨床評価 22: 261-297, 1994.
2) 臨床試験とバイオエシックス (津谷喜一郎司会による坂上正道, 長澤俊彦, 光石忠敬の座談会) . からだの科学196号, 1997 年9 月.
3) Approval of New Drugs in the United States-Comparison Wite the United Kingdom, Germany, and Japan. JAMA, december 11, 1996-Vol. 276. No. 22 (田中正彦訳, 津谷喜一郎解説, JAMA日本語版 1997年8 月号) .
4) 光石忠敬: 「臨床試験」に対する法と倫理. 「臨床試験-医薬品の適正評価と適正使用のために-」 (内藤周幸編) , 薬事日報社, 1996年9月.
5) 光石忠敬: 臨床研究におけるインフォームド・コンセントの基本問題. 呼吸と循環 45 (11) : 1997.
P.808 掲載の参考文献
1) ICH E 9 Step 2 guideline: Statistical principles for clinical tricals. 1997. (日本語訳, 原文: 薬理と治療 25 (supple. 4) : S 879-916 (訳) , S 917-962 (原文) , 1997.
2) Senn S: Statistical issues in drug development, Willey, 1997.
3) Kleinbaum DG, Kupper LL, Morgenstern H: Epidemiologic research-principle and quantitative methods. Van Norstrand Reinhold Company, NY, 1982.
5) Bernard C: Introduction a letude de la medicine experimentale. Paris, 1865. (日本語訳: 実験医学序説. クロード・ベルナール (三浦岱栄訳) , 東京創元社, 1961.)
6) Cushing H: The life of Sir William Osler, Vols 1 and 2, 0xford University Press, London, 1940.
7) ニュールンベルグ綱領, 1947. (原典: United States v. Karl Brandt, Trials of war criminals befor the Nuremberg military tribunals under council law No. 10 vols 1 and 2, "The Medical Case" (Medical Tribunal 1, 1947: Washington, D. C., U. S. government printing office, 1948-49) : Katz J, Experimentation with human being, 292- 306, New York, Russell Sage Foundation, 1972. および Alexander L, Medical science under dictatorship, N. Engl. J. Med. 241: 39-47, 1949. を参照)
8) Faden RR, Beauchamp TL: A history and theory of informed consent. Oxford University Press, NY, 1986. (日本語訳: 酒井忠昭, 秦浄一訳: インフォームド・コンセント 患者の選択. みすず書房, 1994.)
9) The world medical association, INC.: Declaration of Helsinki: Recommendations guiding physisans in biomedical research involving human subjects (Helsinki 1964, Tokyo 1975, Venice 1983, Hong Kong 1989, Somerset West 1996) . (原文, 日本語訳: 日本製薬工業協会医薬品評価委員会 (編集) : 新GCP関連資料集. (株) ミクス, 1997, pp. 491-501.)
10) 下山正徳: インフォームド・コンセント-歴史的展開と最近の動向. 臨床科学 33: 389-397, 1997.
11) 厚生省薬務局長通知: 医薬品の臨床試験の実施に関する基準 (GCP) について. 厚生省薬発第874号, 平成元年10月2日. (GCPとそのマニュアルおよびGCP関係通知, 関連事項などについては「GCPハンドブック: 医薬品の臨床試 験の実施に関する基準, 厚生省薬務局審査第一課監修, 産業時報社, 1990」, および「GCPの理解のために-厚生省説明会講演内容を中心として-. (株) ミクス, 1990. 」 などに一括されているほか, 臨床評価 17: 323-332, 1989; 同 18: 159-168, 1990; 同 18: 169-194, 1990. にも掲載されている.
13) 下山正徳, 江口研二 , 恒松隆一郎・他: 厚生省がん研究助成金指定研究「固形がんの集学的治療の研究」班における臨床試験計画 (プロトコール) の作成と実施, 並びに結果の統計解析と評価について (改訂第3版) . 第II部がん臨床試験のインフォームド・コンセントの指針. 癌の臨床 42: 441-454, 1996.
14) 厚生省健康政策局総務課監修: 元気の出るインフォームド・コンセント (柳田邦男編集) , 中央法規, 東京, 1996. (柳田邦男 (座長) ほかによる厚生省「インフォームド・コンセントの在り方に関する検討会」: インフォームド・コンセントの在り方に関する報告書. 厚生福祉(第4375号) : 10-15, 1995.)
15) ICH E 6: International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use. ICH Harmonized Tripartite Guideline. GUIDELINE FOR GOOD CLINICAL PRACTICE. Recommended for Adoption at Step 4 of the ICH Process on 1 May 1996 by the ICH Steering Committee, 1996.
16) 下山正徳, 大橋靖雄, 西條長宏・他, 厚生省厚生科学研究費による「抗悪性腫瘍薬の第I相試験に関するガイドライン適正化研究」班: 抗悪性腫瘍薬の第I相試験のガイドライン. 薬理と治療 26 (4) : 441-454, 1998.
17) 江口研二編: がん治療・臨床試験のインフォームド・コンセント. 南江堂, 東京, 1997.
18) Federal Register, part 56. Institutional Review Boards, Vol 46, No. 17, January 27, 1981, pp. 8975-8980.
19) Human subjects research: A handbook for institutional review boards (ed by Greenwald RA, Ryam MK, Celvihill JE) , Plenum Press, NY, 1982. (日本語訳: 阿岸鉄三, 今里嘉夫, 土肥修司 (訳) : 被験者保護ハンドブック-アメリカIRB の活動-. 地人書館, 東京, 1987.
20) ICH E 2 a: International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use. ICH Harmonized Tripartite Guideline. CLINICAL SAFETY DATA MANAGEMENT: DEFINITIONS AND STANDARDS FOR EXPEDITED REPORTING. Recommended for Adoption at Step 4 of the ICH Process on 27 October 1994 by the ICH Steering Committee, 1994.
21) 下山正徳, 田島絹子, 大橋靖雄: がん臨床試験の統計センターシステムの開発研究 I. 統計センターシステムの開発. 癌の臨床 43: 87-116, 1997.
22) South West Oncology Group (SWOG) , Statistical center, Fred Hutchinson Cancer Research Center, Washington, March 1997.
23) 日本製薬工業協会医薬品評価委員会 (西岡正基・他) : 米国における治験実施の実状と今後の日本への提言-モニタリングおよびデータマネジメント米国調査団における調査結果を踏まえて-. 臨床医薬 13: 3337-3357, 1997.
24) Gabor A: The man who discovered quality. How W. E. Deming brought the quality revolution to America-The stories of Ford, Xerox, and GM. Random House Inc, New York, 1990. (日本語訳: 鈴木主税訳: デミングで甦ったアメリカ企業. 草思社, 東京, 1994.)
25) 広井良典: 医療保険改革の構想, 日本経済新聞社, 東京, 1997.
15a) 日本版新 GCP: 医薬品の臨床試験の実施に関する基準に関する省令 (厚生省令第28号) , 官報 (号外第58号) pp. 6-12 (平成9年3月27日) . (この取扱いは平成9年3月27日薬発第 430 号薬務局長通知「医薬品の臨床試験の実施 の基準に関する省令の施行について」に示されている. また平成9年3月13日付で「医薬品の臨床試験の実施の基準 (GCP) の内容」として, 中央薬事審議会答申 (中薬審第40号) がまとめられている. さらに, 平成9年5月29日薬 審第445号薬務局審査課長通知/薬安第68号薬務局安全課長通知として「医薬品の臨床試験の実施の基準の運用について」が出されている. これには省令の条文ごとに薬務局長通知や答申の内容が整理されている.)
20a) 日本公定書協会編: 治験中に得られる安全性情報の取扱いについて. (厚生省薬務局審査課長通知, 薬審第227号, 平成7年3月20日. 原文をもとに意訳してあるが, 削除されている部分がある) . 新薬臨床評価ガイドライン, 薬事 日報社, 東京, 1995, pp. 439-451.
20b) 島田安博, 下山正徳, 田村友秀・他, 厚生省がん研究助成金指定研究「固形がんの集学的治療の研究」班 (8S-1) の効果・安全性評価委員会: Japan Clinical Oncology Group (JCOG) の臨床安全性情報取扱いガイドライン. 薬理 と治療 26: 263-274, 1998.
P.825 掲載の参考文献
4) Conquest of Cancer, Report of the National Panel of Consultants of the Committee on Labor and Public Welfare United States Senate, November 1970, p. 51.
5) 辻井博彦: 線量集中照射法の可能性について. 癌の臨床 43: 215-220, 1997.
6) Larsson B: The new radiations in cancer therapy. Hadrontherapy in Oncology (Eds. by Amaldi U and Larsson B) . Elsevier Science B. V., Amsterdam, 1994, pp. 33-44.
13) Raju MR: Heavy Particle Radiotherapy. Academic Press, New York, 1980.
14) Hall E: New radiation modalities. Radiobiology for the Radiologist (Ed. Hall EJ) . 4th ed. J. B. Lippincott Co., Philadelphia, 1994, pp. 231-244.
15) Suit HD, Goitein, M: Rationale for use of carged-particle and fast neutron beams in radiation therapy. Radiation Biology in Cancer Res (ed. by Meyn RE) . Raven Press, New York, 1980, pp. 547-565.
18) Wambersie A: Is there any future for high-LET radiation? Strahlenther. Onkol. 165: 348-356, 1989.
20) Castro JR: Future research strategy for heavy ion radiotherapy. Progress in Radio-Oncology (ed. by Kogelnik HD) , Monduzzi Editore, Italy, 1995, pp. 643-648.
23) Alamdi U, Arduini G, Cambria R, et al: A hospital-based hadrontherapy facility in Italy. Hadrontherapy in Oncology (eds. by Amaldi U, Larsson B) , Elsevier Sciences B. V., Netherlands, 1994, pp. 329-339.
24) Bryant Ph, Kogelnik HD, Pavlovic M, et al: Ion cancer therapy research as part of the AUSTRON project. Hadrontherapy in Oncology (eds. by Amaldi U, Larsson B) , Elsevier Sciences B. V., Netherlands, 1994, pp. 390-399.
27) Endo M, Koyama-Ito H, Minohara S, et al: HIPLAN-A heavy ion treatment planning system at HIMAC. J. Jpn. Soc. Ther. Radiol. Oncol. 8: 231-238, 1996.
29) Osaka Y, Kamada T, Matsuoka Y, et al: Clinical experience of heavy ion irradiation synchronous with respiration. Proc. of XII ICCR. 176-177, 1997.
32) Peters LJ, Fischer JJ, Fuks Z, et al: Proton beam therapy: rationale, current status, future prospects and economic implications. A report of the NCAB by a select panel appointed by the Board of Scientific Counsellors, Division of Cancer Treatment, 1992.
35) Tsujii H, Morita S, Miyamoto T, et al: The current status and perspective of heavy-ion therapy. International Meetiong on Progress in Radio-Oncology VI. Ed. Kogelnik HD, and Sedlmayer F, Monduzzi Editore, Milano, pp. 709-721, 1998.
36) Tsujii H, Morita S, Miyamoto T, et al: Preliminary results of Phase I/II carbon-ion therapy. J. Brachytherapy Int. 13: 1-8, 1997.
37) Lillis-Hearne PK, Castro JR: Indications for heavy-ions-Lesson from Berkeley. Ion Beams in Tumor Therapy (ed. Linz U) , Chapman & Hall, London, 1995, pp. 133-141.
P.830 掲載の参考文献
4) Barr H, Shepherd NA, Dix A, et al: Eradication of high-grade dysplasia in columner-lined (Barrett’s) oesophagus by photodynamic therapy with endogenously generated protoporphyrin IX. Lancet 348: 584-585, 1996.
10) Steiner RA, Tadir Y, Tromberg B, et al: Benzoporphyrin derivative mono acid for photodynamic therapy of the endometrium. Geburtshilfe Frauenheilkd. 56: 1-7, 1996.
11) Wierrani F, Fiedler D, Schnitzhofer G, et al: A new approach to cancer therapy due to appropriate uptake and retention kinetics of meta-tetrahydroxy-phenylchlorin in a human fibroblast cell line. Cancer Biochem. Biophys. 15: 171-176, 1996.
18) Vandenbogaerde AL, Geboes KR, Cuveele JF, et al: Antitumor activity of photosensitized hypericin on A 431 cell xenografts. Anticancer Res. 16: 1619-1625, 1996.
25) 中島進, 坂田功, 竹村健: ポルフィリン誘導体の腫瘍組織集積性のメカニズムとがん診断, 治療への応用. ポルフィリン・ヘムの生命科学, 東京化学同人, 東京, 1994, pp. 209-216.
30) Peterson CM, Lu JM, Sun Y, et al: Combination chemotherapy and photodynamic therapy with N-(2-hydroxypropyl) methacrylamide copolymer-bound anticancer drugs inhibit human ovarian carcinoma heterotransplanted in nude mice. Cancer Res. 56: 3980-3985, 1996.
31) 熊坂英雄, Ilyar X, 荒明美奈子・ほか: アドリアマイシン耐性株に対し, ME 2906を用いたPDT効果. 第7回国際光化学治療学会日本支部例会, 1997.
33) Krosl G, Korbelik M, Krosl J, et al: Potentiation of photodynamic therapy-elicited antitumor response by localized treatment with granulocyte-macrophage colony-stimulating factor. Cancer Res. 56: 3281-3286, 1996.
34) 金子貞男, 松本亮二, 小濱好彦: 悪性腫瘍患者に対する光線力学療法の治療成績. 第15回日本レーザー医学会大会, 45-48, 1994.
35) Konaka C, Okunaka T, Kato H: Combined use of photodynamic therapy and surgery. Ann. Thora. Cardiovasc. Surg. 1 (1) : 55-59, 1995.
36) Gomer CJ, Ryter SW, Ferrario A, et al: Photodynamic therapy-mediated oxidative stress can induce expression of heat shock proteins. Cancer Res. 56: 2355-2360, 1996.
39) Chan WS, Brasseur N, La Madeleine C, et al: Evidence for different mechanisms of EMT-6 tumor necrosis by photodynamic therapy with disulfonated alminum phthalocyanine or photofrin: tumor cell survival and blood flow. Anticancer Res. 16: 1887-1892, 1996.
40) Korbelik M, Krosl G, Krosl J, et al: The role of host lymphoid populations in the response of mouse EMT 6 tumor to photodynamic therapy. Cancer Res. 56: 5647-5652, 1996.
41) Konaka C, Okunaka T, Furukawa K, et al: Photodynamic therapy for maltiple primary lung cancer. Jpn. J. Cancer Chem. 23: 31-35, 1996.
42) Shimao H, Hiki Y: Photodynamic therapy for esophageal cancer. Jpn. J. Cancer Chem. 23: 36-40, 1996.
44) Muroya T, Suehiro Y, Umayahara K, et al: Photodynamic therapy (PDT) for early cervical cancer. Jpn. J. Cancer Chem. 23: 47-56, 1996.
45) Molpus KL, Kato D, Hamblin MR, et al: Intraperitoneal photodynamic therapy of human epithelial ovarian carcinomatosis in a xenograft murine model. Cancer Res. 56: 1075-1082, 1996.
P.836 掲載の参考文献
P.838 掲載の参考文献
1) Beck C: On external roentgen treatment of internal structures (eventration treatment) . NY Med. J. 89: 621-622, 1990.
3) 高橋正治, 芝本雄太, 阿部光幸: 術中照射. がん放射線治療マニュアル (柄川順編) . 中外医学社, 東京, 1989, pp. 386- 399.
4) 坂本澄彦: 術中照射の放射線生物学的考察. 最新醫學 41: 1468-1472, 1986.
8) 秦 一雄, 三好真琴, 上原 智・他: 従来の放射線機器を用いた新しい放射線療法: 術中照射. 癌と化学療法 14: 1564-1569, 1987.
9) 尾崎秀雄, 木下 平, 小菅智男・他: 切除可能膵癌における集学的治療の成績. 代謝 27: 339-344, 1990.
12) 田中良明, 松田忠義, 竹下祥敬・他: 膵癌の術中照射治療成績-術後原体照射を組み合わせた治療法の検討-. J. Jpn. Soc. Cancer Ther. 22: 573-581, 1987.
13) 若杉英之, 瀬尾洋介, 秦 一雄・他: 切除不能膵癌の放射線療法. 胆と膵 11: 933-939, 1990.
14) 秦 一雄, 和田 進, 宮崎麻知子・他: 膵癌-非切除進行癌に対する治療: 術中照射. 肝胆膵 25: 795-799, 1992.
22) 河村 正, 片岡正明, 高嶋成光・他: 膵がんにおける術中照射の検討. 日医放会誌 51: 1442-1453, 1991.
23) 竜 崇正, 小西 大, 古瀬純司・他: 膵胆道がんに対する集学的治療. 臨床医 21: 64-68, 1995.
27) 竜 崇正, 佐藤滋宏, 渡辺一男・他: 進行胆道癌に対するremote after loading system (RALS) を用いた胆管腔内照射法の検討. 胆道 2: 127-137, 1988.
32) 轟 健, 川本 徹, 小池直人: 胆道癌-切除例に対する治療: 放射線療法. 術中照射. 肝胆膵 25: 763-773, 1992.
33) Busse PM, Stone MD, Sheldon TA, et al: Intraoperative radiation therapy for biliary tract carcinoma: results of a 5-year experience. Surgery 105: 724-733, 1989.
43) 児島真一, 佐竹一郎, 辻井俊彦・他: 前立腺癌に対する術中照射術. 泌尿器科紀要 34: 1397-1402, 1988.
44) Kotoura Y, Yamamura T, Kasahara K, et al: Intraoperative radiation therapy for osteosarcoma (meeting abstract) . International Congress of Radiation Oncology 1993. June 21-25, 1993, Kyoto, Japan, p. 359.
55) 柄川 順, 築山 巌, 秋根康之・他: 術中照射における後障害に関する考察. 癌の臨床 36: 815-820, 1990.
P.853 掲載の参考文献
2) Coffin JM: Retroviridare and their replication. Virology (eds by Field BN, Knipe DM, Chanock RM, et al) , 2nd Eds, Raven Press, New York, 1990, pp. 1437-1500.
13) Kato K, Kaneda Y, Sakurai M, et al: Direct injection of hepatitis B virus DNA into liver induced hepatitis in adult rats. J. Biol. Chem. 266: 22071-22074, 1991.
17) Osaki T, Tanio Y, Tachibana I, et al: Gene therapy for carcinoembryonic antigen-producing human lung cancer cells by cell type-specific expression of herpes simplex virus thymidine kinase gene. Cancer Res. 54: 5258-5261, 1994.
19) Huang Y, Snyder R, Kligshteyn M, et al: Prevention of tumor formation in a mouse model of Burkitt’s lymphoma by 6 weeks of treatment with antic-myc DNA phosphorothioate. Mol. Med. 1: 647-658, 1995.
25) Mukhopadhyay T, Tainsky M, Cavender AC, et al: Specific inhibition of K-ras expression and tumorigenicity of lung cancer cells by antisense RNA. Cancer Res. 51: 1744-1748, 1991.
26) Georges RN, Mukhopadhyay T, Zhang Y, et al: Prevention of orthotopic human lung cancer growth by intratracheal instillation of a retroviral antisense K-ras construct. Cancer Res. 53: 1743-1746, 1993.
29) Kashani-Sabet M, Funato T, Florenes VA, et al: Suppression of the neoplastic phenotype in vivo by an antiras ribozyme. Cancer Res. 54: 900-902, 1994.
31) Cheng J, Yee JK, Yeargin J, et al: Suppression of acute lymphoblastic leukemia by the human wild-type p 53 gene. Cancer Res. 52: 222-226, 1992.
39) Gansbacher B, Zier K, Cronin K, et al: Retroviral gene transfer induced constitutive expression of interleukin-2 or interferon-γ in irradiated human melanoma cells. Blood 80: 2817-2825, 1992.
41) McBride WH, Thacker JD, Comora S, et al: Genetic modification of a murine fibrosarcoma to produce interleukin-7 stimulates host cell infiltration and tumor immunity. Cancer Res. 52: 3931-3937, 1992.
44) Tahara H, Zeh III HJ, Storkus WJ, et al: Fibroblasts genetically engineered to secrete interleukin-12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo. Cancer Res. 54: 182-189, 1994.
50) Sakamaki S, Kuga T, Niitu Y, et al: In preparation.
P.865 掲載の参考文献
1) 多田正弘, 村田 誠, 村上不二夫・他: Strip-off biopsy の開発, Gastroenterol. Endosc. 26: 833-839, 1984.
2) 常岡健二 , 内田隆也: われわれの考案した内視鏡下の胃ポリープ切断採取法-ポリープ切断器および採取器について. Gastroenterol. Endosc. 11: 174-183, 1969.
3) 丹羽寛文: 生検用ファイバースコープの改良並びにカラーテレビジョンおよび高周波電流の内視鏡への応用. Gas- troenterol. Endosc. 10: 315, 1968.
5) 小黒八七郎, 福富久之, 崎田隆夫・他: 隆起型早期癌に対するポリペクトミーの経験. 消化器内視鏡の進歩 5: 77-80, 1974.
6) 竹腰隆男, 田尻久男, 大橋計彦・他: 胃生検とPolypectomy標本診断の対比検討-Endoscopic double snare polypectomy の有用性について. 日癌治会誌 16: 395, 1980.
7) 平尾雅紀, 小林多加志, 長谷良志男・他: 胃の腫瘍性病変に対する内視鏡的切除法. Gastroenterol. Endosc. 25: 194- 195, 1983.
8) 多田正弘, 村田 誠, 村上不二夫・他: Strip-off biopsy の開発. Gastroenterol. Endosc. 26: 833-839, 1984.
9) 渡辺 豊, 神山正之, 長尾房大: 胃癌の内視鏡的治療-外科の立場からの適応と問題点. 胃と腸 19: 873-833, 1984.
10) 田尻久雄, 向井俊一, 吉田茂昭・他: 消化器癌に対する内視鏡治療の適応と問題点. 癌と化学療法 15: 1429-1434, 1988.
11) 梨本 篤, 田中甲介, 宮下 薫・他: 早期胃癌の臨床理学的検討-早期胃癌に対する内視鏡治療の適応と限界を知るために. 日外会誌 89: 1780-1788, 1988.
12) 多田正弘, 苅田幹雄, 柳井秀雄・他: Strip biopsy による早期胃癌の内視鏡治療. 癌と化学療法 15: 1460-1465, 1988.
13) 井上晴洋, 遠藤光夫, 竹下公矢・他: 透明プラスチックキャップを用いた内視鏡的食道粘膜切除術 (EMRC) . Gas- trointerol. Endosc. 34: 2387-2390, 1992.
14) 増田勝紀, 篠崎順子, 鈴木博昭・他: Ligating device を利用した内視鏡的粘膜 (EMRL) . 消化器内視鏡 5: 1215- 1219, 1993.
15) 赤坂祐三, 奥田順一, 井上和徳: 食道ルゴール法の基礎と臨床的応用について. Gastroenterol. Endosc. 18: 84-91, 1976.
16) 神津照雄, 山田英夫, 小野田昌一・他: 表在食道癌におけるルゴール染色の診断的価値. 胃と腸 22: 1395-1401, 1987.
17) 幕内博康: 食道粘膜癌に対する内視鏡の治療の適応と限界. 日消外会誌 24: 2599-2603, 1991.
18) 有馬美和子, 神津照雄: 食道の内視鏡的粘膜切除術の適応, 食道, 胃の内視鏡的粘膜切除術. (幕内博康編集) 日本メディカルセンター, 東京, 1997, p. 23.
19) 森川丘道, 神津照雄, 有馬美和子・他: 高周波数細経超音波プローブによる食道内ラジアル走査-表在食道癌深達度診断の検討, 腹部画像診断 14: 604-614, 1994.
20) 有馬美和子, 神津照雄, 森川丘道・他: 食道癌の深達度, リンパ節転移診断, 消化器内視鏡 8: 100-106, 1996.
22) 門馬久美子, 吉田 操, 山田義也・他: 早期食道癌に対する内視鏡的粘膜切除術の実際. 胃と腸 28: 141-151, 1993.
23) 幕内博康: 食道癌の診断と治療の進歩. 最新醫學 52: 175-186, 1997.
25) 中野和夫, 柳澤昭夫, 宇都出公也・他: 未分化型胃癌に対する内視鏡的粘膜切除 (EMR) の適応限界. 胃と腸 30: 1289-1294, 1995.
27) 細川浩一, 白尾国昭, 小黒八七郎・他: 早期胃癌における内視鏡的粘膜切除術-適応の再検討. 消化器内視鏡の進歩 42: 11-15, 1993.
28) 竹腰隆男: 内視鏡による早期胃癌治療の適応と限界. 日本医事新報 3720: 3-16, 1995.
29) 蜂巣 忠: 改良型クリップ装置 (XL-3L) による経内視鏡的止血. 消化器内視鏡 1: 325-332, 1989.
30) 原 宏介: 高齢者部検例における腸管隆起性病変. 日外会誌 74: 18-32, 1973.
31) 多田正大, 藤田直子: 微小病変, 小病変はどこまで治療すべきか. 大腸ポリペクトミーはどこまで必要か. (中村孝司 監修) , 日本メディカルセンター, 東京, 1997, p. 25.
32) 岡本春彦, 畠山勝義: 微小病変, 小病変はどの程度発見されるか. (3) 大学病院の場合. 大腸ポリペクトミーはどこまで必要か. 日本メディカルセンター, 東京, 1997, p. 35.
33) 小平 進, 八尾恒良, 中村恭一・他: sm癌細分類からみた転移陽性大腸sm癌の実態, アンケート調査集計報告. 胃と腸 29: 1137-1142, 1994.
34) 河野弘志, 鶴田 修: 現時点における内視鏡治療の実態. (中村孝司監修) , 日本メディカルセンター, 東京, 1997, p. 17.
35) 片倉重弘: クリップ付加法. 消化器内視鏡の基本手技, 金原出版, 東京, 1996, p. 243.
37) 工藤進英: 早期大腸癌. 平坦陥凹型のアプローチ. (長廻紘編) , 医学書院, 東京, 1993, p. 78.
39) 工藤進英: 早期大腸癌. 平坦・陥凹型へのアプローチ. 医学書院, 東京, 1993, p. 58.
40) 工藤進英, 中島孝司: 粘膜切除, 大腸. 消化器内視鏡の基本手技. (藤田力也編) , 金原出版, 東京, 1996, p. 101.
41) 渡邊昌彦, 大上正裕, 寺本龍王・他: 早期大腸癌に対する腹腔鏡下大腸切除. 手術 47: 651-658, 1993.
42) 林 賢, 宗像康博: 結脹切除術-主としてどんな疾患に-. カレントテラピー 12: 76-82, 1994.
43) 北條慶一・他: 日本大腸肛門会誌 50: 1128-1131, 1997.
44) Jacobs M. Verdeja JC, Plasencia G: Laparscopic surgery. In: Surgical Laparoscopy Update (ed by Zucker KA) , Quality Medical, St. Loui, 1993, pp. 327-354.
45) 宗像康博, 林 賢: 大腸癌に対する腹腔鏡下リンパ節郭清術. 手術 48: 861-867, 1994.
46) 大橋秀一: 腹腔鏡下胃内手術. 手術 48: 333-337, 1994.
47) 大上正祐, 若林 剛, 才川義明・他: 早期胃癌に対する腹腔鏡下手術-腹腔鏡下胃局所切除術及び腹腔鏡併用胃内粘膜切除術. 手術 48: 817-827, 1994.
49) 若林 剛, 北島政樹: 腹腔鏡下肝切除術. 内視鏡下外科手術の現況. 消化器病セミナー 65: 121-130, 1996.
50) 二ツ木浩一, 井田和徳, 小黒八七郎: 進行性消化管癌のレーザー治療の現状-レーザー内視鏡委員会による第7回集計報告-. Gastroenterol. Endosc. 35: 128-134, 1993.
51) Kawai K, Akasaka T, Hashimoto Y, et al: Preliminary report on endoscopic papillotomy. J. Kyoto Pref. Unv. Med. 82: 353-355, 1973.
53) 相馬 智, 立川 勲, 岡本安弘・他: 内視鏡的乳頭切開術および遺残結石摘出の試み (第一報) . Gastroenterol. Endosc. 16: 446-452, 1974.
56) 小川 薫, 長田太郎, 松山秀二郎・他: 悪性胆道狭窄に対する self-expandable metalic stent (金属ステント) による胆道内瘻術の治療成績. 消化器科 24: 82-85, 1997.
57) 宇野耕治, 中島正継, 安田健二郎・他: 内視鏡下 stenting における各種ステントの評価. 胆と膵 18: 549-554, 1997.
P.880 掲載の参考文献
14) Unger M: Neodymium: YAG laser therapy for malignant and benign endobronchial obstruction. Clin. Chest Med. 6: 277-290, 1985.
25) Yankauer S: Lung tumor treated bronchoscopically. NY Med. J. 115: 741-742, 1922.
27) Fuwa N: The clinical utility of 192 iridium endobronchial irradiation for chest X-P negative lung cancer. JJSB 16: 723-729, 1994.
28) Speiser B, et al: High dose rate remote afterloading endobronchial carcinoma. In: Brachytherapy HDR and LDR (eds by Martinez AA, Orton CG, Mould RF) , Nucletron, Columbia, 1989, pp. 10-26.
34) Brut PA, O’Driscoll R, Notely HM, et al: Intraluminal irradiation for the palliation of lung cancer with the high dose rate micro-Selectron. Thorax 45: 765-768, 1990.
42) 水渡哲史, 谷 源一, 関 隆郎・他: 気道閉塞に対する気管支鏡的マイクロ波凝固の使用経験. 気管支学 11: 88-92, 1989.
43) 瀬戸貴司, 千葉 浩, 深井祐治・他: マイクロウェーブによる気道内腫瘍凝固術の有効性. 気管支学 18: 430-436, 1996.
47) Freitag L, Eicher R, Linz B, et al: Theoretical and experimental basis for the development of a dynamic air stent. Eur. Respr. J. 7: 2038-2045, 1994.
49) Maeda M, Uchida H, Otsuji H, et al: Spiral zigzag stents for tracheobronchial stenosis. Radiology 185 (P) (suppl.) : 357, 1992. 78th Scientific Assembly and Annual Meeting.
58) 飯岡壮吾, 東条 尚, 尾辻秀明・他: 癌性気道閉塞に対する内視鏡的治療-金属ステントとcontact YAG-laserを用いて-. 気管支学 13: 154-158, 1991.
61) Breyer G, Haussinger K: Tracheobronchiale Stents-Indikationen und Moglichkeiten. Pneumologie 45: 997-1003, 1991.
62) 飯岡壮吾, 東条 尚, 北村惣一郎・他: 癌性気管支狭窄に対する金属ステント拡張術. 気管支学 13: 500-505, 1991.
66) 岸 和史, 小林 尚, 駿田直俊・他: 癌性気管支狭窄に対するDacron mesh 張り金属stent による治療. 気管支学 14: 443-448, 1992.
69) Maeda M, Uchida H, Otsuji H, et al: Spiral zigzag stents for tracheobronchial stenosis. Radiology 185 (P) (suppl.) : 357, 1992. 78 th Scientific Assembly and Annual Meeting.
72) Hurter Th, Bohndorf K, Kropff M, et al: Bronchiale Endoprosthesen (Stents) beim inoperablen Bronchialkarzinom. Pneumologie 45: 19-22, 1991.
75) Cortese DA, Parirolero PC, Gergstrail EJ, et al: Roentgenographically occult lung cancer. J. Thorac. Cardiovasc. Surg. 86: 373-380, 1980.
79) 塚越 茂: ポルフィマーナトリウム (Photofrin II) について. 癌と化学療法 22: 1271-1278, 1995.
80) 小中千守, 奥中哲也, 古川欣也・他: 原発性多発肺癌の光線力学的治療. 癌と化学療法 23: 31-35, 1996.
82) Cortese DA, Kinsey JH: Endoscopic management of lung cancer with hematoporphyrin derivative phototherapy. Mayo Clin. Proc. 57: 543-547, 1982.
86) 加藤治文, 奥中哲弥, 小中千守: 肺癌に対する光線力学的治療. 日外会誌 98: 36-40, 1997.
89) Lam S: Photodynamic therapy of lung cancer. Semin. Oncol. 21 (suppl. 15) : 15-19, 1994.
90) Pass HI: Photodynamic therapy for lung cancer. Chest Surg. Clin. North Am. 1: 135-151, 1991.
93) Macha HN, Wahlers B: Endobronchiale Brachytherapie: Die endoluminale Kleinraum-bestrahlung von Bronchialtumoren mit dem Afterloading HDR-Verfahren. Pneumonologie 45: 95-99, 1991.
95) 植島久雄, 飯岡壮吾, 多田弘人・他: 肺門部早期肺癌に対するBrachytherapyの問題点. 肺癌 37: 622, 1997. 第38 回日本肺癌学会総会号抄録.
P.907 掲載の参考文献
1) 佐藤武男: 現状の概観と問題点, 図説臨床[癌]シリーズ. 頭頸部癌 No. 11 (末舛恵一, 佐藤武男編) , メジカルビュー社, 東京, 1987, pp. 6-13.
2) Schottenfeld D: Epidemiology, etiology, and pathogenesis of head and neck cancer. In: Head and Neck Cancer vol 1 (ed by Chretien PB, Johns ME, et al) , B. C. Decker, Philadelphia, 1985, pp. 6-18.
3) 日本頭頸部腫瘍学会編: V. 病理組織分類, 臨床・病理頭頸部癌取扱い規約. 金原出版, 東京, 1991, pp. 15-18.
4) 古川政樹, 古川まどか, 松田秀樹・他: (特集) 外来診療と検査, 超音波検査法-外来診療を中心に. JOHNS 10: 1419- 1426, 1994.
5) 小山和行: (特集) これからの画像診断X線CT画像の基礎と撮影法. JOHNS 12: 1227-1236, 1996.
6) 小山和行: (特集) これからの画像診断 頭頸部MR診断に必要な基礎知識. JOHNS 12: 1275-1286, 1996.
7) 戸辺公子, 多湖正夫, 吉川宏起: (特集) これからの画像診断三次元CT. JOHNS 12: 1253-1262, 1996.
8) 宇野公一, 内田佳孝, 今関恵子・他: (特集) これからの画像診断 PETによる腫瘍診断. JOHNS 12: 1363-1370, 1996.
9) 木田亮紀, 横出 裕: (特集) 頭頸部癌診療 腫瘍マーカー. JOHNS 7: 575-578, 1991.
10) 横浜優樹, 滝沢昌彦, 犬山征夫・他: 頭頸部扁平上皮癌における新しい腫瘍マーカーサイトケラチン19 (CYFRA21-1) の臨床的有用性の検討. 頭頸部腫瘍21: 370, 1995.
11) 行木英生: (特集) Quality of Life と再建外科, QOLを考慮した頭蓋底の再建外科. JOHNS 10: 87-93, 1994.
12) 犬山征夫: (特集) 頭頸部の早期癌, 放射線治療・化学療法併用の適応となる頭頸部早期癌. JOHNS 13: 567-573, 1997.
13) UICC: TNM Classification of Malignant Tumours. fifth revised edition, Springer-Verlag, Berlin, New York, Tokyo, 1997.
14) Easson EC, Palmer MK: Prognostic factors in oral cancer. Clin. Oncol. 2: 191-202, 1976.
18) Langdon JD: Epidemiology and aetiology. In: Malignant Tumours of the Oral Cavity (ed by Henken JM, Langdon JD) , Edward Arnold Publications, London, 1985, pp. 1-5.
20) Rudert H, Neumann FW, Gremmel H: Results of the treatment of 197 squamous cell carcinomas of the oropharynx (1964-1982 treatment period) . HNO 34: 357-364, 1986.
23) Lundy J, Raaf JH, Deakins S, et al: The acute and chronic effects of alcohol on the human immune system. Surg. Gynecol. Obstet. 141: 212-218, 1975.
29) Cachin Y, Sancho-Garnier H, Micheau C, et al: Nodal metastasis from carcinomas of the oropharynx. Otolaryngol. Clin. North Am. 12: 145-154, 1979.
30) Snow GB, Balm AJM, Arendse JW, et al: Prognostic factors in neck node metastasis. In: Cancer in the Neck: Evaluation and Treatment (eds by Larson DL, Ballantyne AJ, Guillamondegui OM) , McMillan, New York, 1977, pp. 53-63.
44) Sidransky D: Molecular markers in head and neck cancer. Proc of 4th International Conference on Head and Neck Cancer, SHNS and ASHNS, Pittsburgh, 1996, pp. 509-515.
47) 犬山征夫編著: 頭頸部癌治療における化学療法の役割. 東京医学社, 東京, 1997, pp. 168-184.
49) 犬山征夫監修: 頭頸部がんの境界領域における治療法の最新の進歩. 協和企画通信, 東京, 1995, pp. 124-131.
50) Shah JP: Head and Neck Surgery. 2nd ed, Mosby-Wolfe, New York, 1996, pp. 85-141.
51) Cantu G, Solero CL, Salvatori P, et al: Anterior craniofacial resection for ethmoidal malignant tumors. A series of 91 patients. Proc 4 th International Conference on Head and Neck Cancer, 1996, p. 69.
52) Robbins KT: Targetted supradose cisplatin and concomitant radiotherapy for advanced upper aerodigestive tract carcinoma. Scientific Program and Abstracts of International Meeting on Intra-arterial Chemotherapy in Head and Neck Cancer, 1997, p. 17.
53) 犬山征夫, 福田 諭, 八木克憲・他: (特集) 口腔癌治療方針とその選択-化学療法の立場から-. JOHNS 6: 199- 205, 1990.
54) 堀内淳一: II. 頭頸部腫瘍放射線治療の実際, 2. 口腔, 頭頸部腫瘍の放射線治療-よりよいQOLと集学的治療- (堀内淳一, 大川智彦編) , 金原出版, 東京, 1993, pp. 156-170.
55) Wolf GT, Lippman SM, Hong WK, et al: Head and neck cancer. In: Cancer Medicine vol 1 (eds by Holland JF, Frei III E, et al) , 3rd ed, Lea & Febiger, Philadelphia, 1993, pp. 1228-1230.
58) Al-Sarraf M, LeBlanc M, Giri PGS, et al: Superiority of chemoradiotherapy vs radiotherapy in patients with locally advanced nasopharyngeal cancer. Preliminary results of Intergroup (0099) randomized study. Proc. ASCO15: 313, 1996.
59) Wei IW, Lam LK, Yuen PW, et al: Surgical resection for recurrent nasopharngeal carcinoma-the pathologicbasis. Proc of 4 th International Conference on Head and Neck Cancer, SHNS and ASHNS, 1996, pp. 611-616.
60) 鎌田信悦: 頭蓋底外科-[附]頭蓋底手術におけるMRI診断のキー・ポイント. 耳喉頭頸 67: 618-635, 1995.
61) 犬山征夫編著: 頭頸部癌治療における化学療法の役割. 東京医学社, 東京, 1997, pp. 235-263.
62) 藤田昌宏, 真崎規江, 村山重行・他: 頭頸部腫瘍に対する少量 Cisplatin の連日投与併用放射線治療. 日放腫会誌 2: 255-262, 1990.
65) Mendenhall WM, Parsons JT, Stringer SP, et al: Radiotherapy in the treatment of squamous cell carcinoma of the hypopharynx and cervical esophagus. Proc of 4 th International Conference on Head and Neck Cancer, SHNS and ASHNS, 1996, pp. 175-180.
66) 中塚貴志: (特集) Quality of Lifeと再建外科 遊離空腸. JOHNS 10: 55-58, 1994.
67) 中塚貴志: 遊離結腸移植を用いた下咽頭癌切除後の再建. 頭頸部腫瘍 20: 214, 1994.
68) 奥芝俊一, 加藤紘之, 犬山征夫・他: 頭頸部領域癌に対する食道切除・再建症例の検討. 日臨外医会誌 54: 861-864, 1993.
69) Lefbbvre J-L: Cancer of the hypopharynx: Strategies for larynx preservation. Proc of 4 th International Conference on Head and Neck Cancer, SHNS and ASHNS, 1996, pp. 170-174.
70) Bryce PP: The management of laryngeal cancer. J Otolaryngol. 8: 105-126, 1979.
85) Croll GA, Gerritsen GJ, Tiwari RM, et al: Primary radiotherapy with surgery in reserve for advanced laryngealcarcinoma: Results and complications. Eur. J. Surg. Oncol. 15: 350-356, 1989.
92) Hong WK, Lippman SM, Wolf GT: Recent advances in head and neck cancer-Larynx preservation and cancer chemoprevention. Cancer Res. 53: 5113-5120, 1993,
93) Wolf GT, Hong WK, Fisher S, et al: Larynx preservation with induction chemotherapy and radiation inadvanced laryngeal cancer: Final results of the VA Laryngeal Cancer Study Group Cooperative Trial. Proc. ASCO 12: 277, 1993.
95) Tapley N: Irradiation treatment of malignant tumors of the salivary glands. Ear Nose Throat. J. 56: 110-114, 1977.
99) Johns ME, Kaplan MJ: Malignant neoplasms. In: Otolaryngology Head and Neck Surgery vol 2 (eds by Cummings CW, Fredreickson JM, et al) , Mosby, St Louis, 1986, pp. 1043-1078.
102) Robbins KT: Neck dissection: classification and incisions. In: The Neck, diagnosis and surgery (eds byShockery WW, Pillsbury III HC) , Mosby, St Louis, 1994, pp. 381-391.
P.931 掲載の参考文献
1) 厚生省老人保健福祉部老人保健課: 老人保健法による肺がん検診マニュアル. 日本醫事新報社, 東京, 1992, pp. 6.
3) Ihde DC, Pass HI, Glatstein E: Small cell lung cancer. In: Cancer: Principles & Practice of Oncology. 5th Edition (eds. by DeVita VT Jr, Hellman S, Rosenberg SA) , Lippincott-Raven, Philadelphia, 1997, pp. 911-949.
4) 岡村明治, 坂井田紀子: I. 診断と病態 5. 病理-組織分類と腺癌の発生母地. 日内会誌 86: 27-32, 1997.
5) 北川正信, 浅川三男, 井内康輝・他: 6. 組織分類, 臨床・病理. 肺癌取り扱い規約 (日本肺癌学会編) , 金原出版, 東京, 1995, pp. 89-121.
7) Minna JD, Sekido Y, Fong K, et al: Molecular biology of lung cancer. In: Cancer: Principles & Practice of Oncology. 5th Edition (eds. by DeVita VT Jr, Hellman S, Rosenberg SA) , Lippincott-Raven, Philadelphia, 1997, pp. 849-857.
8) Johnson BE: The role of MYC, JUN, and FOS oncogenes in human lung cancer. In: Lung cancer: Principles and Practice (eds. by Pass HI, Mitchell JB, Johnson DH, et al) . Lippincott-Raven, Philadelphia, 1996, pp. 83-98.
10) Jiang SX, Kameya T, Sato Y, et al: Bcl-2 protein expression in lung cancer and close correlation with neuroendocrine differentiation. Am. J. Pathol. 148: 837-846, 1996.
13) 秋田弘俊, 川上義和: 小細胞肺がんにおける遺伝子異常. 最新醫學 52: 2661-2666, 1997.
15) 桑原正喜, 柴田典子, 有吉 寛: 腫瘍マーカーの進歩. 日内会誌 86: 20-26, 1997.
23) Poplin E, Thompson B, Whitacre M, et al: Small cell carcinoma of the lung: Influence of age on treatment outcome. Cancer Treat. Rep. 71: 291-296, 1987.
24) Zelen M: Keynote adress on biostatistics and data retrieval Cancer Chemother. Rep. 4: 31-42, 1973.
31) Aisner J, Alberto P, Bitran J, et al: Role of chemotherapy in small cell lung cancer: A consensus report of the international association for the study of lung cancer workshop. Cancer Treat. Rep. 67: 37-43, 1983.
32) 根来俊一, 福岡正博, 仁井谷久暢・他: カンプトテシン誘導体CPT-11の原発性肺癌に対する後期第II相臨床試験. 癌と化学療法 18: 1013-1019, 1991.
33) Negoro S, Fukuoka M, Niitani H, et al: Phase II study of CPT-11, new camptothecin derivative, in small cell lung cancer (SCLC) . Proc, Am. Soc. Clin. Oncol. 101241, 1991 (abstr.) .
35) Le Chevalier T, Ibrahim N, Chomy P, et al: A phase II study of irinotecan (CPT-11) in patients (pts) with small cell lung cancer (SCLC) progressing after initial response to first-line chemotherapy (CT) . Proc. Am. Soc. Clin. Oncol. 16: 450a, 1997 (abstr.) .
40) Kirschling RJ, Jung SH, Jett JR: A phase II Study of taxol and GCSF in previously unterated patients with extensive stage small cell lung cancer (SCC) . Proc. Am. Soc. Clin. Oncol. 13: 326, 1994 (abstr.) .
42) 横山 晶, 栗田雄三, 渡辺古志郎・他: 原発性肺癌に対するRP 56976 (docetaxel) の前期第II相臨床試験. 癌と化学療法 21: 2609-2616, 1994.
47) Lake D, Johnson E, Herndon J, et al: Phase II trial of Navelbine (NVB) in relapsed small cell lung cancer (SCLC) . Proc. Am. Soc. Clin. Oncol. 16: 473 a, 1997 (abstr.) .
48) 根来俊一, 梁 尚志, 横田総一郎・他: SM-5887 (amrubicin) の進展型小細胞肺癌に対する第II相臨床試験. 日癌治療会誌 32: 508, 1997 (抄録) .
49) 福岡正博: 肺癌, 呼吸器腫瘍, 小細胞癌. 最新内科学大系63, (井村裕夫, 尾形悦郎, 高久文麿, 他編) , 中山書店, 東京, 1994, pp. 163-181.
50) Einhorn LH, Greco A, Wampler G, et al: Cytoxan, adriamycin, etoposide versus cytoxan, adriamycin, vincristine in the treatment of small cell lung cancer. Proc. Am. Soc. Clin. Oncol. 6: 168, 1987 (abstr.) .
53) Messeih AA, Schweitzer JM, Lipton A, et al: Addition of etoposide to cyclophosphamide, doxorubicine, and vincristine for remission induction and survival in patients with small cell lung cancer. Cancer Treat. Rep. 71: 61-66, 1987.
55) Schabel FM, Trader MW, Laster WK, et al: Cisdichlorodiammineplatinum (II) : Combination chemotherapy and cross-resistance studies with tumors of mice. Cancer Treat. Rep. 63: 1459-1473, 1979.
57) Porter LL 3 rd, Johnson DH, Hainsworth JD, et al: Cisplatin and etoposide combination chemotherapy for refractory small cell carcinoma of the lung. Cancer Treat. Rep. 69: 479-481, 1985.
60) Sierocki JS, Hilaris BS, Hopfan S, et al: Cisdichlorodiammineplatinum (II) and VP-16-213: An active induction regimen for small cell carcinoma of the lung. Cancer Treat. Rep. 63: 1593-1597, 1978.
70) Goldie JH, Coldman AJ, Gudauskas GA: Rationale for the use of alternating non-cross-resistant chemotherapy. Cancer Treat. Rep. 66: 439-449, 1982.
74) Coldman AJ, Goldie JH: Impact of dose-intense chemotherapy on the development of permanent drug resistance. Semin. Oncol. 14 (Suppl. 4) : 29-33, 1987.
94) Gatzemeier U, Jagos U, Kaukel E, et al: Phase II study of paclitaxel, carboplatin and etoposide in patients with small cell lung cancer. Proc. Am. Soc. Clin. Oncol. 16: 468 a, 1997 (abstr.) .
95) Nair S, Marschke R, Grill J, et al: Aphase II study of paclitaxel (Taxol) and cisplatin (CDDP) in the treatment of extensive stage small cell lung cancer (ESSCLC) . Proc. Am. Soc. Clin. Oncol. 16: 454 a, 1997 (abstr.) .
96) Glisson BS, Kurie JM, Fox NJ, et al: Phase I-II study of cisplatin, etoposide, and paclitaxel (PET) in patients with extensive small cell lung cancer (ESCLC) . Proc. Am. Soc. Clin. Oncol. 16: 455 a, 1997 (abstr.) .
100) Ohta M, Hara N, Ichinose Y, et al: The role of surgical resection in the management of small cell carcinoma of the lung. Jpn. J. Clin. Oncol. 16: 289-296, 1986.
105) Lad T, Thomas P, Piantadosi S, et al: Surgical resection of small cell lung cancer-a prospective randomized evaluation. Proc. Am. Soc. Clin. Oncol. 10: 244, 1991 (abstr.) .
107) Tada T, Minakuchi K, Akae M, et al: Local failure in patients treated with chemo-radiotherapy for limited disease small cell lung cancer. Proc. RSNA Radiology l997 (abstr.) .
110) Mornex F, Trillet V, Chauvin F, et al: Hyperfractionated radiotherapy alternating with multidrug chemotherapy in the treatment of limited small cell lung cancer (SCLC) . Groupe Lyonnais d’Oncologie Thoracique. Int. J. Radiat. Oncol. Biol. Phys. 19: 23-30, 1990.
117) Johnson DH, Kim K, Sause W, et al: Cisplatin (P) & etoposide (E) + thoracic radiotherapy (TRT) administeredonce or twice daily (BID) in limited stage (LS) small cell lung cancer (SCLC) : Final report of Intergroup Trial OO96. Proc. Am. Soc. Clin. Oncol. 15: 374, 1996 (abstr.) .
120) Murray N, Payne DG, Coldman AJ: Multimodality therapy for limited small cell lung cancer: Combining chemotherapy and thoracic irradiation. In: Lung cancer: principles and practice (eds. by Pass HI, Mitchell JB, Johnson DH, et al) , Lippincott-Raven, Philadelphia, 1996, pp. 875-898.
127) Lebeau B, Chastang CI, Urban T, et al: Arandomized clinical trial comparing concurrent and alternated thoracic irradiation in limited small cell lung cancer (SCLC) . Proc. Am. Soc. Clin. Oncol. 15: 383, 1996 (abstr.) .
131) Turrisi AT, Wagner D, Glover B, et al: Limited small cell lung cancer: concurrent BID thoracic radiotherapy with platinum-etoposide: an ECOG study. Proc. Am. Soc. Clin. Oncol. 9: 230, 1990 (abstr.) .
133) Takada M, Fukuoka M, Furuse K, et al: Phase III study of concurrent versus sequential thoracic radiotherapy (TRT) in combination with cisplatin (C) and etoposide (E) for limited-stage (LS) small cell lung cancer (SCLC) : Preliminary results of the Japan Clinical Oncology Group (JCOG) . Proc. Am. Soc. Clin. Oncol. 15: 372, 1996 (abstr.) .
135) 新部英男, 長谷川正俊: 放射線治療に伴う副作用 急性障害とその対策. 癌・放射線療法 ' 95 (大川智彦編) , 篠原出版, 東京, 1995, pp. 395-406.
136) 酒井邦夫, 末山博男: 放射線治療の晩期障害とその対策. 癌・放射線療法'95 (大川智彦編) , 篠原出版, 東京, 1995, pp. 407-418.
147) Eagan RT, Frytak S, Lee RE, et al: Acase for preplanned thoracic and prophylactic whole brain radiation therapy in limited small cell lung cancer. Cancer Clin. Trials 4: 261-266, 1981.
148) Katsenia AT, Karpasitis N, Giannakakis D, et al: Elective brain irradiation in patients with small-cell carcinoma of the lung: Preliminary report. Lung Cancer International Congress Series 558, Excepta Medica, Amsterdam, 1982, pp, 277-284.
150) Aroney RS, Aisner J, Wesley MN, et al: Value of prophylactic cranial irradiation given at complete remission in small cell lung carcinoma. Cancer Treat. Rep. 67: 675-682, 1983.
156) 上岡 博, 大熨泰亮, 沼田健之・他: 肺小細胞癌における再発様式の検討とその対策. 日胸疾会誌 28: 1581-1587, 1990.
158) 多田卓仁, 水口和夫, 甲田真由子・他: 限局型小細胞肺癌完全寛解症例に対する Prophylactic Cranial Irradiation. 肺癌37: 849-854, 1997.
165) 池田裕子, 田中正博, 小田淳郎・他: 転移性脳腫瘍に対する定位手術的照射と全脳照射. 日放腫会誌 10: 61-68, 1988.
174) DeVore RF, Blanke CD, Denham CA, et al: Phase II study of irinoteca (CPT-11) in patients with previous lytreated small-cell lung cancer (SCLC) . Proc. Am. Soc. Clin. Oncol. 17: 451 a, 1998 (abstr.) .
175) Burris HA, Crowley JJ, Williamson DR, et al: Docetaxel (Taxotere) in extensive stage small cell lung cancer (SCLC) : Aphase II trial of the Southwest Oncology Group (SWOG) . Proc. Am. Soc. Clin. Oncol. 17: 451 a, 1998 (abstr.) .
178) Smit EF, Fokkema E, Biesma B, et al: Aphase II study of paclitaxel (P) and carboplatin (C) in patients (PTS) with early relapse small cell lung cancer (SCLC) . Proc. Am. Soc. Clin. Oncol. 17: 474 a, 1998 (abstr.) .
179) Sonpavde G, Ansari R and Einhorn LH: Aphase II trial of bolus doxorubicin and 3-hour paclitaxel as second line chemotherapy of small-cell lung cancer: AHoosier Oncology Group (HOG) Trial. Proc. Am. Soc. Clin. Oncol. 17: 475 a, 1998 (abstr.) .
181) 野本靖史, 宮本忠昭, 安川朋久・他: 肺小細胞癌脳転移に対する放射線療法-適正制御線量の検討-. 日医放会誌 58: 226-234, 998.
182) Turrisi AT: Personal communication. May 1998.
117 ') Turrisi A, Kim K, Sause W, et al: Observations after Syear follow-up of Intergroup Trial OO96: 4 cycles of cisplatin (P) Etoposide (E) and concurrent 45 Gy thoracic radio therapy (TRT) given in daily (QD) or twice daily fractions followed by 25 Gy PCI. Survival differences and patterns of failure. Proc. Am. Soc. Clin. Oncol. 17: 457a, 1998 (abstr.) .
P.960 掲載の参考文献
2) 国民衛生の動向. 厚生の指標 (臨時増刊) 44巻9号, 厚生統計協会, 1997.
3) Bellin NI, Buncher CR, Fontana RS, et al: National Cancer Institute Cooperative lung Cancer Detection Program: Results of initial screen (prevalence) early lung cancer detection-Introduction. Am. Rev. Resp. Dis. 130: 545-549, 1984.
4) Bellin NI, Buncher CR, Fontana RS, et al: Early lung cancer detection: Summary and conclusions. Am. Rev. Resp. Dis. 130: 565-570, 1984.
7) 日本肺癌学会組織分類委員会: 組織分類. 臨床・病理肺癌取扱い規約 (日本肺癌学会編) , 改訂第4版, 金原出版, 東京, 1995, pp. 90-121,
22) Goldstraw P, Mannam GC, Kaplan DK, Michail P: Surgical management of non-small-cell lung cancer with ipsilateral mediastinal node metastasis (N 2 disease) . J Thorac. Cardiovasc. Surg. 107: 19-27, 1994.
31) Mastrorilli M, Bragaglia RB, Cippola D, et al: The tracheo-bronchioplastic procedure for lung cancer. Lung Cancer 4: 87, 1988 (Abstr.) .
40) Brunner KW, Marthaler T, Muller W: Effects of long-term adjuvant chemotherapy with cyclophosphamide (NSC-2627. 2) for radically resected bronchogenic carcinoma. Cancer Chemother. Rep. 4: 125-132, 1973.
52) Takifuji N, Fukuoka M, Yasumitsu T, et al: Neoadjuvant chemotherapy in stage IIIA N 2 non-small cell lung cancer (NSCLC) . Proc. Am. Soc. Clin. Oncol. 11: 309, 1992 (Abstr.) .
56) Eagan RT, Ruud C, Lee RE, et al: Pilot study of induction therapy with cyclophosphamide, doxorubicin, and cisplatin (CAP) and chest irradiation prior to thoracotomy in initially inoperable stage III M O non-small cell lung cancer. Cancer Treat. Rep. 71: 895-900, 1987.
60) Kirn DH, Lynch TJ, Mentzer SJ, et al: Multimodality therapy of patients with stage IIIA, N 2 non-small-cell lung cancer. Impact of preoperative chemotherapy on resectability and downstaging. J. Thorac. Cardiovasc. Surg. 106: 696-702, 1993.
78) Dillman RO, Seagren SL, Herndon J, et al: Randomized trial of induction chemotherapy plus radiation therapy vs. RT alone in stage III non-small cell lung cancer: five year follow-up of CALGB 84-33. Proc. Am. Soc. Clin. Oncol. 12: 329, 1993 (Abstr.) .
81) Friess GG, Baikadi M, Harvey WH: Concurrent cisplatin and etoposide with radiotherapy in locally advanced non-small cell lung cancer. Cancer Treat. Rep. 71: 681-684, 1987.
86) Furuse K, Fukuoka M, Takada Y, et al: A randomized phase III study of concurrent versus sequential thoracic radiotherapy (TRT) in combination with mitomycin (M) , vindesine (V) , and cisplatin (P) in unresectable stage III non-small cell lung cancer (NSCLC) : preliminary analysis. Proc. Am. Soc. Clin. Oncol. 16: 459a, 1996 (Abstr.) .
91) Kudoh S, Kurihara N, Okishio K, et al: A phase I-II study of weekly irinotecan (CPT-11) and simultaneous thoracic radiotherapy (TRT) for unresectable locally advanced non-small cell lung cancer (NSCLC) . Proc. Am. Soc. Clin. Oncol. 15: 372, 1996 (Abstr.) .
105) Kris M, Gralla R, Kalman L, et al: Randomized trial comparing vindesine plus cisplatin with vinblastine plus cisplatin in patient with non-small cell lung cancer with an analysis of methods of response assessment. Cancer Treat. Rep. 69: 387-395, 1985.
117) Kris M, Gralla R, Wertheim M: Trial of the combination of mitomycin, vindesine and cisplatin in patients with advanced non-small cell lung cancer. Cancer Treat. Rep. 70: 1091-1096, 1985.
120) Folman RS, Rosman M: The role of chemotherapy in non-small cell lung cancer: the community perspective. Semin. Oncol. 15 (suppl. 4) : 16-21, 1988.
122) Klastersky J, Sculier Jp, Nicaise C, et al: Combination chemotherapy with cisplatin, etoposide, and vindesine in non-small cell lung carcinoma: a clinical trial of the EORTC lung cancer working party. Cancer Treat. Rep. 67: 727-730, 1983.
123) Hainsworth JD, Porter LL, Johnson DH, et al: Combination chemotherapy with vindesine, etoposide, and cisplatin in non-small cell lung cancer: a pilot study of the Southeastern Cancer Study Group. Cancer Treat. Rep. 70: 339-341, 1986.
124) Giron C, Ordonez A, Jalon I, et al: Combination chemotherapy with ifosfamide, mitomycin, and cisplatin in advanced non-small cell lung cancer. Cancer Treat. Rep. 71: 851-853, 1987.
128) 西脇 裕, 児玉哲郎, 林辺 晃 他: 進行非小細胞肺癌に対するCDDP+VDSとCDDP+MMC+VDSの比較試験: 肺癌 28: 581, 1988 (Abstr.) .
137) Quoix E, Dietemann A, Charbonneau J, et al: Is cisplatin-based chemotherapy useful in disseminated non-small cell lung cancer? Report of a French multicenter randomized trial. Cancer Bull. 78: 341-346, 1991.
144) Bunn PA Jr, Kelly K: New chemotherapeutic agents prolong survival and improve quality of life in non-small cell lung cancer: a review of the literature and future. Clin. Cancer Res. 4: 1087-1100, 1998.
156) Sekine I, Nishiwaki Y, Watanabe K, et al: Phase II study of 3-hour infusion of paclitaxel in previously untreated non-small cell lung cancer. Clin. Caner Res. 2: 941-945, 1996.
159) Belli L, Le Chevalier T, Gottfried M, et al: Phase I-II trial of paclitaxel (taxol(R)) and cisplatin in previously untreated advanced non-small cell lung cancer (NSCLC) . Proc. Am. Soc. Clin. Oncol. 14: 350, 1995 (Abstr.) .
160) von Pawel J, Wagner H, Niederle N, et al: Phase II study of paclitaxel and cisplatin in patients with non-small cell lung cancer. Semin. Oncol. 23 (6 Suppl. 16) : 47-50, 1996.
161) Bonomi P, Kim K, Chang A, et al: Phase III trial comparing etoposide (E) -cisplatin (C) versus Taxol (T) with cisplatin-G-CSF versus Taxol-cisplatin in advanced non-small cell lung cancer: an Eastern Cooperable, Oncology Group (ECOG) trial. Proc. Am. Soc. Clin. Oncol. 15: 382, 1996 (Abstr.) .
163) Gatzemeier U, von Pawel J, Gottfried M, et al: Phase III study of high-dose cisplatin (HD-cis) versus a combination of paclitaxel (TAX) and cisplatin (cis) in patients with advanced non-small cell lung cancer (NSCLC) . Proc. Am. Soc. Clin. Oncol. 17: 454 a, 1998 (Abstr.) .
165) Belani CP, Aisner J, Hiponia D, et al: Paclitaxel and carboplatin with and without filgrastim support in patients with metastatic non-small cell lung cancer. Semin. Oncol. 22 (Suppl. 9) : 7-12, 1995.
166) Muggia FM, Vatai D, Natale R, et al: Paclitaxel 3-hour infusion given alone and combination with carboplatin: preliminary results of dose-escalation trials. Semin. Oncol. 22 (Suppl. 9) : 63-66, 1995.
167) Johnson DH, Paul DM, Hande KR, et al: Paclitaxel plus carboplatin for advanced lung cancer: preliminary results of Vanderbilt University phase II trial-LUN-46. Semin. Oncol. 22 (Suppl. 9) 130-33, 1995.
170) Paccagnella A, Favaretto A, Oniga F, et al: Paclitaxel and carboplatin: a phase I study in advanced non-small cell lung cancer. Semin. Oncol. 23 (6 Suppl. 16) 176-79, 1996.
172) Belani CP, Natale RB, Lee JS, et al: Randomized phase III trial comparing cisplatin/etoposide versus carboplatin/ paclitaxel in advanced and metastatic non-small cell lung cancer (NSCLC) . Proc. Am. Soc. Clin. Oncol. 17: 455a, 1998 (Abstr.) .
173) Burris H, Eckardt N, Fields S, et al: Phase II trial of taxotere in patients with non-small cell lung cancer. Proc. Am. Soc. Clin. Oncol. 12: 335, 1993 (Abstr.) .
178) 工藤翔二, 日野光紀, 藤田昭久・他: 非小細胞肺癌に対するRP 56976 (Docetaxel) の後期第II相臨床試験. 癌と化学療法 21: 2617-2623, 1994.
182) Le Chevalier T, Belli L, Monnier A, et al: Phase II study of docetaxel (taxotere(R)) and cisplatin in advanced non-small-cell lung cancer (NSCLC) : an interim analysis. Proc. Am. Soc. Clin. Oncol. 14: 350, 1995 (Abstr.) .
183) Cole JT, Gralla RJ, Marques CB, et al: Phase I-II study of cisplatin+docetaxel (taxotere) in non-small cell lung cancer (NSCLC) . Proc. Am. Soc. Clin. Oncol. 14: 357, 1995 (Abstr.) .
200) Steward WP, Dunlop DJ, Dabouis G, et al: Phase I/II study of gemcitabine and cisplatin in the treatment of advanced non-small cell lung cancer. Semin. Oncol. 23 (5 Suppl. 10) : 43-47, 1996.
202) Shepherd FA, Cormier Y, Burkes R, et al: Phase II trial of gemcitabine and weekly cisplatin for advanced nonsmall cell lung cancer. Semin. Oncol. 24 (3 Suppl. 8) : S 8-27-S 8-30, 1997.
203) Shephard FA, Anglin G, Abratt R, et al: Influence of gemcitabine (GEM) and cisplatin (CP) schedule on response and survival in advanced non-small cel川ung cancer. Proc. Am. Soc. Clin. Oncol. 17: 472 a, 1998 (Abstr.) .
206) Cardenal F, Rosell R, Anton A, et al: Gemcitabine+cisplatin versus etoposide+cisplatin in advanced non-small cell lung cancer patients: preliminary randomized phase III results. Proc. Am. Soc. Clin. Oncol. 16: 458 a, 1997 (Abstr.) .
207) Crino L, Conte P, De Marinis F, et al: A randomized trial of gemcitabine and cisplatin (GP) versus mitomycin, ifosfamide and cisplatin (MIC) in advanced non-small cell lung cancer (NSCLC) . Amulticenter phase III study. Proc. Am. Soc. Clin. Oncol. 17: 455 a, 1998 (Abstr.) .
208) Sandler A, Nemunaitis J, Dehnam Y, et al: Phase III study of cisplatin (C) with or without gemcitabine (G) in patients with advanced non-small cell lung cancer (NSCLC) . Proc. Am. Soc. Clin. Oncol. 17: 454 a, 1998 (Abstr.) .
209) Furuse K, Fukuoka M, Ohshima S, et al: Phase II clinical study of (glycolato-0, O') diammine platinum (II) (254-S) , anew platinum complex, for primary lung cancer. Proc. Am. Soc. Clin. Oncol. 8: 238, 1989 (Abstr.) .
210) Takifuji N, Negoro S, Ariyoshi Y, et al: Phase II study of amurubicin (SM-5887) , anovel 9-amino-anthracycline in advanced non-small cell lung cancer (NSCLC) : the studies of West Japan Lung Cancer Group. Proc. Am. Soc. Clin. Oncol. 16: 485 a, 1997 (Abstr.) .
217) Yana T, Fukuoka M, Kurihara N, et al: Intrapleural (IP) cisplatin (P) and etoposide (E) in the management of non-small-cell lung cancer (NSCLC) with malignant pleural effusions (MPE) . Proc. Am. Soc. Clin. Oncol. 14: 361, 1995 (Abstr.) .
220) Stanley KE: Prognostic factors for survival in patients with inoperable lung cancer. J. Natl. Cancer Inst. 65: 25-32, 1980.
226) Quinlan DC, Davidson AG, Summers CL, et al: Accumulation of p 53 protein correlates with a poor prognosisin human lung cancer. Cancer Res. 52: 4828-4831, 1992.
230) Volm M, Hahn EW, Mattern J, et al: Five-year follow-up study of independent clinical and flow cytometric prognostic factors for the survival of patients with non-small cell lung carcinoma. Cancer Res. 48: 2923-2928, 1988.
P.982 掲載の参考文献
2) Shimosato Y, Mukai K: Tumors of the mediastinum. AFIP, Bethesda, 1997, pp. 120-158.
11) Pollack A: Thymoma: treatment and prognosis. Int. J. Radiat. Biol. Phys. 2311037-1043, 1992.
12) Blumberg D: Thymoma: amultivariate analysis of factors predicting survival. Ann. Thorac. Surg. 54: 311-315, 1992.
15) Oshita F: Intensive chemotherapy with cisplatin, doxorubicin, cyclophosphimide etoposide and colony-stimulating factor for advanced thymoma or thymic cancer: preliminary results. Jpn. J. Clin. Oncol. 25: 208-212, 1995.
16) 浅村尚生, 森永正二郎, 下里幸雄・他: 縦隔原発びまん性硬化性大細胞型悪性リンパ腫の3例. 病理と臨床 6: 81-87, 1988.
25) Hainsworth JD, Greco FA: Mediastinal germ cell neoplasms. In: Thoracic Oncology (eds. by Roth JA, Ruckdeschel JC, Weisenburger TH) . W. B. Saunders, Philaderlphia, 1989, pp. 478-489.
26) Shimosato Y, Mukai K: Tumors of the mediastinum. AFIP, Bethesda, 1997, pp. 263-267.
P.997 掲載の参考文献
1) Parkin M, Muir C, Whelan S, et al: Cancer incidence in five continents, vol 6. International Agency for Research on Cancer. Lyon, France, 1992.
2) Yang CS: Research on esophageal cancer in China: a review. J. Thorac. Cardiovasc. Surg. 40: 2633, 1980.
4) Day NE, Varghese C: Oesophageal cancer. Cancer Surv. 19/20: 43-54, 1994.
6) Blot WJ: Cancer of the esophagus: its causes and changing patterns of occurrence. Proc. Am. Soc. Clin. Oncol. 16: 159-163, 1997.
7) がんの統計編集委員会編: がんの統計 1997.
8) Blot WJ: Esophageal cancer trends and risk factors. Semin. Oncol. 21: 403-410, 1994.
9) Munoz N, Day NE: Esophageal cancer. In: Cancer epidemiology and prevention (eds. by Schottenfeld D, Fraumeni J Jr) (ed 2) . University Press, New York, NY Oxford, 1996, pp. 681-706.
10) Blot WJ: Alcohol and cancer. Cancer Res. 52: 2119 s-2123 s, 1992.
12) Spechler SJ: Barrett 's esophagus. Semin. Oncol. 21: 435-437, 1994.
16) Shu YJ: Cytopathology of the esophagus: an overview of esophageal cytopathology in China. Acta Cytol. 27: 7-16, 1983.
21) 食道疾患研究会 (編) : 臨床・病理食道癌取扱い規約. 第8版, 金原出版, 東京, 1992.
25) Suzuki H, Nagayo T: Primary tumors of the esophagus other than squamous cell carcinoma. Histologic classification and statistics in the surgical and autopsied materials in Japan. Int. Adv. Surg. Oncol. 3: 73-109, 1980.
26) 真船健一, 田久保海誉, 田中洋一: 食道原発腺様嚢胞癌の1例. 癌の臨床 32: 513-519, 1986.
27) Bedi DG, Shaw MT: Oat cell carcinoma of the esophagus: unusual radiologic appearance. Eur. J. Radiol. 6: 233-237, 1986.
28) 食道疾患研究会, 国立がんセンター: 全国食道がん登録調査報告. 第12号 (昭和59年症例) : 69, 1992.
31) Iyomasa S, Kato H, Tachimori Y, et al: Carcinosarcoma of the esophagus: a twenty-case study. Jpn. J. Clin. Oncol. 20: 99-106, 1990.
34) 小玉正智: 食道表在癌の全国集計報告. 第49回食道疾患研究会アンケート調査, 1995.
37) 井出博子, 野上 厚, 葉梨智子 他: 食道sm癌の臨床診断と予後. 胃と腸 25: 1067-1074, 1990.
38) 吉田 操, 室井正彦, 門馬久美子 他: 食道m・sm癌の質的診断ならびに鑑別診断. 胃と腸 25: 1059-1066, 1990.
41) 幕内博康, 町村貴郎, 水谷郷一・他: 内視鏡による食道表在癌-癌の深達度診断の精度-. 胃と腸 27: 175-184, 1992.
42) Murata Y, Hayashi K, Kobayashi A, et al: Preoperative staging of esophageal carcinoma by ultrasound. Asian J. Surg. 17: 200-207, 1994.
43) Sugimachi K, Ohno S, Fujishima H, et al: Endoscopic ultrasonographic detection of carcinomatous invasion and lymph nodes in the thoracic esophagus. Surgery 107: 366-371, 1990.
45) 井出博子: 食道がん治療における最近の動向. 臨床腫瘍学 (日本臨床腫瘍研究会編) . 癌と化学療法社, 東京, 1994, pp. 570-594.
46) 岩崎善毅, 小池盛雄, 滝沢登一郎・他: 食道表在癌の病理. 病理と臨床 12: 536-541, 1994.
47) 鶴丸昌彦, 宇田川晴司, 梶山美明・他: 手術成績からみた食道癌に対する術式選択 1) 胸部食道扁平上皮癌に対する拡大郭清の適応と限界. 外科診療 57: 1032-1046, 1995.
48) 中村正徳, 永井 鑑, 河野辰幸・他: 食道癌治療上の問題点: 診断はどこまで可能か, 深達度 (内視鏡, EUS) -表在癌の細分類診断を中心に-. 外科診療 37: 649-657, 1995.
49) 中村 努, 井手博子, 江口礼紀・他: 食道癌の病理・2) 早期癌, 表在癌. 外科 57: 1020-1022, 1995.
50) 幕内博康, 町村貴郎, 水谷郷・他: 早期食道癌に対する内視鏡的粘膜切除術-EEMR-tube法の実際-. 胃と腸 28: 153-159, 1993.
51) 幕内博康, 町村貴郎, 島田英雄・他: 早期食道癌に対する内視鏡的粘膜切除術-内視鏡的粘膜切除術-. 外科 57: 1027-1031, 1995.
54) Dawsey SM, Yu Y, taylor PR, et al: Esophageal cytology and subsequent risk of esophageal cancer: a prospective follow-up study from Linxian, China. Acta Cytol. 38: 183-192, 1994.
55) 門馬久美子, 吉田 操, 山田義也・他: 早期食道癌に対する内視鏡的粘膜切除の実際-2チャンネル法-胃と腸 28: 141-151, 1993.
56) 井上晴洋, 竹下公矢, 長浜雄志・他: 早期食道癌に対する内視鏡的粘膜切除の実際-EMRTとEMRC-. 胃と腸 28: 161-169, 1993.
57) 小山恒男, 宮田佳典, 岡庭信司・他: 内視鏡的食道粘膜切除後の局所再発. 胃と腸 31: 1217-1233, 1996.
58) 門馬久美子, 吉田 操, 加藤久人・他: 内視鏡的食道粘膜切除後にm3・sm1と判明した癌への対応. 胃と腸 28: 1207-1215, 1996.
64) Roth JA, Putnam JB, Rich TA, et al: Cancer of the esophagus. Cancer;principles and practice of oncology. 5 th edition (ed. by Devita VT, et al) , Lippincott-Raven, Philadelphia, 1997, pp. 980-1021.
74) Rosen N: The molecular basis for cellular transformation: implication for esophageal carcinogenesis (Review) . Semin. Oncol. 21: 416-424, 1994.
76) Seitz JF, Monges G, Perrier H, et al: Abscence of surexpression of protein p 53 is a powerful and independent predictor of response to treatment of squamous cell esophageal cancer by concurrent radiochemotherapy: Proc. Am. Soc. Clin. Oncol. 13: 193, 1994.
78) Ajani JA: Contributions of chemotherapy in the treatment of carcinoma of the esophagus: results and commentary. Semin. Oncol. 21: 474-482, 1994.
79) Leichman L, Berry BT: Experience with cisplatin in treatment regimens for esophageal cancer. Semin. Oncol. 18: 64-71, 1991.
81) Byfield JE: Combined modality infusional chemotherapy with radiation. In: Cancer chemotherapy by infusion (ed. by Lokich JJ) , 2nd ed, Percepta Press, Chicago, 1990, pp. 521-551.
85) Engstrom PF, Lavin PT, Klassen DJ: Phase II evaluation of mitomycin and cisplatin in advanced esophageal carcinoma. 67: 713-715, 1983.
86) Whittington R, Close H: Clinical experience with mitomycin-C. Cancer Chemother. Rep. 54: 195-198, 1970.
87) Wittes RE, Adrianza ME, Parsons R, et al: Compilation of phase II results with single antineoplastic agents. Cancer Treatment Symposia 4: 91-130, 1985.
89) Bleiberg H, Jacob J, Bedenne L, et al: Randomized phase II trial of 5-fluorouracil and cisplatin versus cisplatin alone in advanced esophageal cancer. Proc. Am. Soc. Clin. Oncol. 10 (abstr.) : 145, 1991.
91) Ravry M, Moertel CG, Schutt AJ, et al: Treatment of advanced squamous cell carcinoma of the gastrointestinal tract with bleomycin (NSC 125066) . Cancer Chemother. Rep. 57: 493-495, 1973.
93) Kelsen DP, Bains M, Cvitkovic E, et al: Vindesine in the treatment of esophageal carcinoma: a phase II study. Cancer Treat. Rep. 63: 2019-2021, 1979.
95) Bezwoda WR, Derman DP, Weaving A, et al: Treatment of esophageal cancer with vindesine: an open trial. Cancer Treat. Rep. 68: 783-785, 1984.
97) Sternberg C, Kelsen D, Dukemen M, et al: Carboplatin: anew platinum analog in the treatment of epidermoid carcinoma of the esophagus. Cancer Treat. Rep. 69: 1305-1307, 1985.
98) Coonley CJ, Bains M, Heelan R, et al: Phase II study of etoposide in the treatment of esophageal carcinoma. Cancer Treat. Rep. 67: 397-398, 1983.
101) 田口鐵男, 涌井 昭, 鍋谷欣市・他: 254-S (Cis-diammine glycolate platinum) の消化器癌に対する第II相臨床試験. 癌と化学療法 19: 483-488, 1992.
103) Dinwoodie WR, Bartolucci AA, Lyman GH, et al: Phase II evaluation of cisplatin, bleomycin, and vindesine in advanced squamous cell carcinoma of the esophagus: A Southeastern Cancer Study Group trial. Cancer Treat. Rep. 70: 267-270, 1986.
108) Wadler S, Haynes H, Beitler JJ, et al: Phase II clinical trial with 5-fluorouracil, recombinant interferon-α-2 a, and cisplatin for patients with metastatic or regionally advanced carcinoma of the esophagus. Cancer 78: 30-34, 1996.
109) Temeck BK, Liebman JE, Theodossiou C, et al: Phase II trial of 5-fluorouracil, Leucovorin, Interferon-α-2 a, and cisplatin as neoadjuvant chemotherapy for locally advanced esophageal carcinoma. Cancer 77: 2432-2439, 1996.
116) Ohtsu A, Yoshida S, Boku N, et al: Concurrent chemotherapy and radiation therapy for locally advanced carcinoma of the esophagus. Jpn. J. Clin. Oncol. 25: 261-266, 1995.
120) Sischy B, Ryan L, Haller D, et al: Interim report of EST 1282 phase III protocol for the evaluation of combined modalities in the treatment of patients with carcinoma of the esophagus. Proc. Am. Soc. Clin. Oncol. 9 (abstr.) : 105, 1990.
122) Minsky BD: Nonsurgical treatment approaches for esophageal cancer. Proc. Am. Soc. Clin. Oncol. (Educational Book) : 164-174, 1997.
127) Urba S, Orringer M, Turrisi R, et al: A randomized trial comparing surgery to preoperative concomitant chemoradiation plus surgery in patients with resectable esophageal cancer. Proc. Am. Soc. Clin. Oncol. 16: 277, 1997.
132) Javed T, Reed C, Walle T, et al: Aregimen of paclitaxel (P) , cisplatin (CP) and 5-fluorouracil followed by G-CSF is highly active against epidermoid and adenocarcinoma of the esophagus. Proc. Am. Soc. Clin. Oncol. 14: 456, 1995.
133) Ajani JA, Ilson D, Bhala K, et al: Taxol, cisplatin and 5 FU: A multi-institutional phase II study in patients with carcinoma of the esophagus. Proc. Am. Soc. Clin. Oncol. 14: 489, 1995.
134) Ilson D, Arquette M, Costa F, et al: Preoperative paclitaxel/cisplatin in esophageal carcinoma: a phase II multicenter trial. Proc. Am. Soc. Clin. Oncol. 16: 926, 1997.
135) Meluch AA, Hainsworth JD, Thomas M, et al: Preoperative therapy with paclitaxe1, carboplatin, 5-FU, and radiation yields 69%pathologic complete response (CR) rate in the treatment of local esophageal carcinoma. Proc. Am. Soc. Clin. Oncol. 16: 927, 1997.
137) Isaac JR, Sim EK, Ngoi SS, et al: Safe and rapid palliation of dysphagia for carcinoma of the esophagus. Am. Surg. 57: 245, 1991.
143) Vakil N, Bethge N: Metal stent for malignant esophageal obstruction. Am. J. Gastroenterol. 91: 2471-2476, 1996.
P.1014 掲載の参考文献
2) 甲 利幸, 古河 洋, 今岡真義・他: 手術単独治療例の再発形式からみた胸部食道癌治療の問題点-とくに上縦隔郭清の必要性について. 日外会誌 89: 1458-1460, 1989.
3) 松原敏樹, 土屋繁祐, 木下 巌・他: 再発形式からみた胸部食道癌外科療法の問題点. 日外会誌 89: 1461-1464, 1989.
4) Akiyama H: Squamous cell carcinoma of the thoracic esophagus. Surgery for cancer of the esophagus. Williams &Wilkins, Baltimore, 1990, pp. 28-41.
5) 食道疾患研究会: 食道癌取扱い規約. 第8版, 金原出版, 東京, 1992.
6) 安藤暢敏, 小澤壮治, 辻塚一幸・他: 胸部食道癌に対する3領域郭清の功罪. 日消外会誌 28: 937-941, 1995.
7) 鶴丸昌彦: 胸部食道癌に対するリンパ節郭清. 日消外会誌 31: 128-132, 1998.
10) 掛川暉夫: 食道リンパ流の特性に基づいた胸部食道癌の合理的手術方法の研究. 厚生省癌研究助成金による研究報告集(平成2年度) . 国立がんセンター, 東京, 1991, pp. 285-288.
11) 森 昌造: 食道癌の外科的治療-成績向上の道程-. 日外会誌 98: 700-705, 1997.
16) 室井正彦: 胸部食道癌に対するリンパ節拡大郭清法の意義に関する臨床病理学的研究. 日胸外会誌 43: 287-299, 1995.
28) Peracchia A, Bardini R: Total esophagectomy without thoracotomy: Results of a European Questionnaire (GEEMO) . Int. Surg. 71: 171-175, 1986.
29) 神津照雄, 磯野可一: 胸部食道全摘後の胃管による食道再建. 手術 46: 691-698, 1992.
30) Ando N, Shinozawa Y, Ikehata Y, et al: Postoperative nutritional status in patients with esophageal carcinoma. Diseases of the Esophagus. (ed. by Mark K. Ferguson, Alex G. Little and David B. Skinner) , Futra Publishing, New York, 1990, pp. 261-269.
31) 安藤暢敏, 小澤壮治, 北島政樹: 結腸を用いた食道再建. 外科 58: 1532-1536, 1996.
33) 馬場政道, 愛甲 孝, 浅谷倫代・他: 胸部食道癌再建術後の問題点と対策-後縦隔経路と胸骨後経路の優劣-. 日消外会誌 28: 2047-2051, 1995.
34) 丸山圭一, 加藤抱一, 北島政樹: 消化管吻合法のコツGambee1層吻合の利点とその手技. 外科治療 40: 705-713, 1979.
35) 安藤暢敏, 小澤壮治, 三木浩栄 他: 頸部における食道・胃管/結腸器械吻合術. 臨床外科 49: 1233-1240, 1994.
38) 青山法夫, 小泉博義: 切除不能食道癌に対するバイパス手術, ステント挿入. 消化器病セミナー 69: 169-181, 1997.
44) Iizuka T, Kakegawa T, Ide H, et al: Phase II evaluation of cisplatin and vindesine in advanced squamous cell carcinoma of the esophagus: Japanese Esophageal Oncology Group Trial. JPn. J. Clin. Oncol. 21: 176-179, 1991.
45) Iizuka T, Kakegawa T, Ide H, et al: Phase II evaluation of cisplatin and 5-fluorouracil in advanced squamous cell carcinoma of the esophagus: A Japanese Esophageal Oncology Group Trial. JPn. J. Clin. Oncol. 22: 172-176, 1992.
47) Reed CE: Neoadjuvant therapy of esophageal carcinoma. Chest Surg. Clin. N. Am. 4: 299-314, 1994.
48) 安藤暢敏, 小澤壮治, 三木浩榮・他: 食道癌に対する術前化学療法と化学放射線療法. 癌と化学療法 22: 1878-1885, 1995.
50) 南出純二, 小泉博義, 青山法夫・他: 食道癌集学的治療における術前Cisplatin, 5-Fluorouracil併用化学療法の安全性と直接効果に関する検討. 日消外会誌 27: 2384-2390, 1994.
51) 吉田一成, 井手博子, 林 和彦・他: 食道癌に対するCisplatin, 5-FU, Leucovorin 3剤併用による術前化学療法の臨床・病理学的研究. 日胸外会誌 43: 159-167, 1995.
56) Kelsen DP, Ginsberg R, Qian C, et al From RTOG, CALGB, SWOG and ECOG: Chemotherapy followed by operation versus operation alone in the treatment of patients with localized esophageal cancer: apreliminary report of intergroup study 13 (RTOG 89-11) . Proc. Am. Soc. Clin. Oncol. 16: 276 a, 1997.
57) Kok TC, Lanschot JV, Siersema PD, et al: Rotterdam Esophageal Tumor Study Group: Neoadjuvant chemo- therapy in operable esophageal squamous cell cancer: final report of a phase III multicenter randomized controlled trial. Proc. Am. Soc. Clin. Oncol. 16: 277 a, 1997.
71) Apinop C, Puttisak P, Preecha N: Aprospective study of combined therapy in esophageal cancer. Hepatogastroenterology 41: 391-393, 1994.
72) Urba S, Orringer M, Turrisi A, et al: A randomized trial comparing surgery to preoperative concomitant chemoradiation plus surgery in patients with resectable esophageal cancer: update analysis. Proc. Am. Soc. Clin. Oncol. 16: 277 a, 1997.
75) 安藤暢敏, 小澤壮治, 北川雄光・他: T4食道癌に対する化学放射線併用療法後の根治手術. 日外会誌 98: 767-772, 1997.
P.1046 掲載の参考文献
2) Fisher B: The evolution of paradigms for the management of breast cancer: apersonal perspective[Prior annotation incorrect] [published erratum appears in Cancer Res 1992 Jun 15;52 (12) : 3512]. Cancer Res. 52: 2371-2383, 1992.
3) 垣添忠生: 癌の統計. 癌研究振興財団, 1997.
8) Chamberlain J: Epidemiology of breast cancer. In: Breast Cancer. UICC current treatment of cancer (eds. by Hoogstraten B, Burn I, Bloom HJG) . Springer-Verlag, Berlin, 1988.
12) Tominaga S: Breast cancer risk. Nyugan no Rinsho 3: 251-271, 1988.
16) Miki Y, Swensen J, Shattuck-Eidens D, et al: Astrong candidate for the breast and ovarian cancer susceptibility gene BR (]Al. Science 266: 66-71, 1994.
21) Howe GR, Hirohata T, Hislop TG, et al: Analysis of dietary fat, calories, body weight, and the development of mammary tumors in rats and mice: a review. Cancer Res. 50: 5710-5719, 1990.
25) NSABP P 1 trial: Breast cancer prevention trial shows major benefit, some risk. http: //rex. nci. nih. gov/ massmedia/pressreleases/prevtrial. htm., 1998.
27) PDQ of NCI: Screening for breast cancer. http://cancernet. nci. nih. gov/clinpdq/screening/Screening_for_breast_cancer_Physician. html., 1998.
30) 福田 譲: 乳癌集団検診の現状と問題点. 乳癌の臨床 5: 374, 1990.
31) 渡辺 弘, 福田 譲: 乳癌と集団検診. 外科 54: 495-497, 1992.
35) International Union Against Cancer: TNM classification of malignant tumours. (eds. by Sobin L, Wittekind C) (ed 5 th) . Wiley-Liss, Inc., New York, 1997.
36) National Institutes of Health Consensus Development Panel: Consensus Treatment: treatment of early-stage breast cancer. Monogr. Natl. Cancer Inst. 11: 1-5, 1992.
38) 日本乳癌学会編: 臨床・病理乳癌取扱い規約. 第12版, 金原出版, 東京, 1996.
39) Nixon AJ, Troyan SL, Harris JR.: Options in the local management of invasive breast cancer. Semin. Oncol. 23: 453-463, 1996.
42) 池田 正, 富永 健, 山口 晋・他: 乳房温存療法に関するアンケート調査-54施設の集計から-. 乳癌の臨床 10: 526-532, 1995.
45) Veronesi U, Salvadori B, Luini A, et al: Conservative treatment of early breast cancer. Ann. Surg. 211: 250- 259, 1990.
85) Dhingra K, Hortobagyi GN: Critical evaluation of prognostic factors. Semin. Oncol. 23: 436-445, 1996.
92) Bradley SJ, Weaver DW, Bouwman DL: Alternatives in the surgical management of in situ breast cancer. A meta-analysis of outcome. Am. Surg. 56: 428-432, 1990.
98) Henson DE: The histological grading of neoplasms. Arch. Pathol. Lab. Med. 112: 1091-1096, 1988.
99) NIH Consensus Development Conference: Steroid receptors in breast cancer. Cancer 46: 2759-2963, 1980.
101) Berger U, Wilson P, Thethi S, et al: Comparison of an immunocytochemical assay for progesterone receptor with a biochemical method of measurement and immunocytochemical examination of the relationship between progesterone and estrogen receptors. Cancer Res. 49: 5176-5179, 1989.
104) Knight WA, Livingston RB, Gregory EJ, et al: Estrogen receptor as an independent prognostic factor for early recurrence in breast cancer. Cancer Res. 37: 4669-4671, 1977.
105) Clark GM, McGuire WL: Steroid receptors and other prognostic factors in primary breast cancer. Semin. Oncol. 15: 20-25, 1988.
106) Foekens JA, Portengen H, van Putten WL, et al: Prognostic value of estrogen and progesterone receptors measured by enzyme immunoassays in human breast tumor cytosols. Cancer Res. 49: 5823-5828, 1989.
126) Hortobagyi GN, Singletary SE, McNees MD: Treatment of locally advanced and inflammatory breast cancer. In: Disease of the breast (eds. by Harris JR, Lippman ME, Morrow M, et al) (ed 1st) . Lippincott-Raven Publishers, Philadelphia, 1996.
128) Buzdar AU, Hortobagyi GN, Asmar L, et al: Prospective randomized trial of paclitaxel alone versus 5-fluorouracil/ doxorubicin/cyclophosphamide as induction therapy in patients with operable breast cancer. Sem. Oncol. 24: S17-31-S17-34, 1997.
138) Abeloff MD, Lichter AS, Niederhuber JE, et al: Breast. In: Clinical Oncology (eds. by Abeloff MD, Armitage JO, Lichter AS, et al) . Churchill Livingstone, New York, 1995, pp. 1617-1714.
151) Fey MF, Brunner KW, Sonntag RW: Prognostic factors in metastatic breast cancer. Cancer Clin. Trials 4: 237-247, 1981.
155) Carr B: Disorders of the ovary and female reproductive tract. In: Textbook of Endocrinology (eds. by Wilson J, Foster D) (ed 8 th) . W. B. Saunders Company, Philadelphia, 1992, pp. 733-798.
156) Honig S: Treatment of metastatic disease. In: Disease of the breast (eds. by Harris JR, Lippman ME, Morrow M, et al) (ed 1st) . Lippincott-Raven Publishers, Philadelphia, 1996, pp. 669-768.
158) Klijn J, Seynaeve C, Beex L, et al: Combined treatment with buserelin (LH-RH-A) and tamoxifen vs single treatment with each drug alone in premenopausal metastatic breast cancer;preliminary results of EORTC study 10881. Proc. Am. Soc. Clin. Oncol. 15: 117, 1996.
162) Taylor SG, Gelber RD: Experience of the Eastern Cooperative Oncology Group with doxorubicin as a single agent in patierlts with previously untreated breast cancer[letter]. Cancer Treat. Rep. 66: 1594-1595, 1982.
176) Goldie JH, Coldman AJ, Gudauskas GA: Rationale for the use of alternating non-cross-resistant chemotherapy. Cancer Treat. Rep. 66: 439-449, 1982.
178) Smalley RV, Murphy S, Hunguley CM, et al: Combination versus sequential five-drug chemotherapy on metastatic carcinoma of the breast. Cancer Res.: 3911-3916, 1976.
183) Henderson IC, Harris JR: Principles in the management of metastatic disease. In: Breast Disease (eds. by Henderson IC, Harris JR) (ed 2 nd) . Lippincot, New York, 1990, pp. 547-677.
190) Ravdin P, Valeno V, Nabholtz J-M, et al: Efficacy of a five-day corticosteroid premedication in ameliorating taxotere-induced fluid retention. Proc. Am. Soc. Clin. Oncol. (Abstr. #124) . 15: 115, 1996.
192) Cooper RG: Combination chemotherapy in hormone resistant breast cancer. Proc. Am. Assoc. Cancer Res. 10: 15, 1969.
201) Watanabe T: Improving the quality of life of patients with metastatic breast cacner., 1994.
202) Peters WP: High-dose chemotherapy with autologous bone marrow transplantation for the treatment of breast cacner: yes, In: Important advance in oncology 1995 (eds. by DeVita VTJ, Hellman S, Rosenberg SA) . J. B. Lippincott Company, Philadelphia, 1995.
206) Smith GA, Henderson IC: High-dose chemotherapy (HDC) with autologous bone marrow transplantation (ABMT) for the treatment of breast cancer: the jury is still out. In: Important advance in oncology 1995 (eds. by DeVita VTJ, Hellman S, Rosenberg SA) . J. B. Lippincott Company, Philadelphia, 1995.
207) Yamamoto N, Watanabe T, Katsumata N, et al: Construction and validation of a practical prognostic index for patients with metastatic breast cancer. J. Clin. Oncol. (in press)
P.1072 掲載の参考文献
1) 津熊秀明, 北川貴子, 田中明夫・他: 1975-89年の全国罹患率に基づく将来推計. 地域がん登録の精度向上と活用に関する研究 平成6年度研究班報告書 (花井 彩編) , pp. 72-83, 1994.
2) がん研究振興財団: がんの統計 ' 93. 1993.
9) Correa P, Cuello C, Duque E, et al: Carcinoma and intestinal metaplasia in the stomach in Columbian migrants. J. Natl. Cancer Inst. 44: 297-306, 1970.
10) Imai T, Kubo T, Watanabe H: Chronic gastritis in Japanese with reference to high incidence of gastric carcinoma. J. Natl. Cancer Inst. 179-195, 1971.
12) Haenszel W, Kurihara M, Segi M, et al: Lee RKC. Stomach cancer among Japanese in Hawaii. J. Natl. Cancer Inst. 49: 969-988, 1972.
13) Correa P: Clinical implications of recent developments in gastric cancer pathology and epidemiology. Semin. Oncol. 12: 2-10, 1985.
15) Chyou P-H, Nomura AMYH, Hankin JH, et al: Acase-cohort study of diet and stomach cancer. Cancer Res. 50: 7501-7504, 1990.
16) Nomura A, Grove JS, Stemmermann GN, et al: A prospective study of stomach cancer and its relation to diet., cigarettes, and alcohol consumption. Cancer Res. 50: 627-631, 1990.
18) Lygidakis NJ: Gastric stump carcinoma after surgery for gastroduodenal ulcer. Ann. R. Coll. Surg. Engl. 63: 203, 1981.
21) Tersmette AC, Offerhaus GJA, Tersmette KWF, et al: Meta-analysis of gastric stump cancer: detection of high risk patient subsets for stomach cancer after remote partial gastrectomy for benign conditions. Cancer Res. 50: 6486-6489, 1990.
33) Burke AP, Yen TSB, Shekitka KM, et al: Lymphoepithelial carcinoma of the stomach with Epstein-Barr virus demonstrated by polymerase chain reaction. Mod. Pathol. 3: 377-380, 1990.
34) Shibata D, Tokunaga M, Uemura Y, et al: Association of Epstein-Barr virus with undifferentiated gastric carcinomas with intense lymphoid infiltration. Am. J. Pathol. 139: 469-474, 1991.
36) 胃癌研究会編: 胃癌取扱い規約 (改訂第12版) , 金原出版, 東京, 1993.
38) Zinninger M: Extension of gastric cancer in the intramural lymphatics and its relation to gastrectomy. Am. Surg. 20: 920, 1954.
45) Hermanek P: Prognostic factors in stomach cancer surgery. Eur. J. Surg. Oncol. 12: 241-246, 1986.
46) Shiu MH, Perrotti M, Brennan MF: Adenocarcinoma of the stomach: amultivariate analysis of clinical, pathologic and treatment factors. Hepatogastroenterology 36: 7-12, 1989.
47) Okusa T, Nakane Y, Boku T, et al: Quantitative analysis of nodal involvement with respect to survival rate after curative gastrectomy for carcinoma. Surg. Gynecol. Obstet. 170: 488-494, 1990.
50) Yonemura Y, Tsugawa K, Fonseca L, et al: Lymph node metastasis and surgical management of gastric cancer invading the esophagus. Hepatogastroenterology 42: 37-42, 1995.
51) Bozzetti F, Bonafanti G, Morabito A, et al: A multifactorial approach for the prognosis of patients with carcinoma of the stomach after curative resection. Surg. Gynecol. Obstet. 162: 229-234, 1986.
52) Maehara Y, Moriguchi S, Sugimachi K, et al: Prognostic factors in adenocarcinoma in the upper one-third of the stomach. Surg. Gynecol. Obstet. 173: 223-226, 1991.
54) Ohno S, Tomisaki S, Sugimachi K, et al: Clinicopathologic characteristics and outcome of adenocarcinoma of the human gastric cardia in comparison with carcinoma of other regions of the stomach. J. Am. Coll. Surg. 180: 577-582, 1995.
55) 多田正弘, 村上敦司, 苅田幹夫・他: strip biopsyによる早期胃癌の内視鏡治療における長期観察成績. 消化器内視鏡 8: 1515, 1990.
56) 多田正弘, 村田 誠・他: Strip off biopsyの開発. Gastroenterol. Endosc. 26: 833-839, 1984.
57) 平尾雅紀, 高桑良平・他: 早期胃癌に対するHSE局注を併用した内視鏡的粘膜切除法. 胃と腸 23: 399-409. 1988.
58) 竹腰隆雄, 藤井 彰・他: endoscopic double snare polypectomy (EDSP) の方法と評価. 胃と腸 23: 387-398. 1988.
59) 田尻久雄: 早期胃癌に対するレーザー内視鏡治療-接触照射法と非接触照射法の特徴-. 日本レーザー医学会誌 11: 41-44, 1990.
60) 二ツ木浩一, 山本邦男・他: 進行胃癌の癌性狭窄に対するレーザー治療の限界. 臨床消化器内科 8: 681-688, 1993.
62) 谷村 弘, 永井祐吾: 内視鏡的マイクロ波凝固法. 綜合臨床 41: 3240-3247, 1992.
63) 浅木 茂, 佐藤 彰, 斉藤行世: 内視鏡的治療-適応・方法・成績. 局注療法, 胃癌診断と治療 (丹羽寛文編) . 日本メディカルセンター, 東京, 1995, pp. 402-409.
64) 嶋尾 仁, 比企能樹: 狭窄拡張術. 臨床消化器内科 2: 743-751, 1987.
67) 細川浩一, 白尾国昭・他: 早期胃癌における内視鏡的粘膜切除術-適応の再検討-. 消化器内視鏡の進歩 42: 11-15, 1993.
68) 芳野純治: 早期胃癌の内視鏡的粘膜切除-適応拡大をめぐる問題点-. 胃と腸 31: 1065-1066, 1996.
69) 梶山美明, 鶴丸昌彦, 宇田川清司・他: 胃Sm癌の細分類からみた縮小手術の可能性 多変量解析を用いたリンパ節転移の予測と腹腔鏡下切除の可能性. 胃と腸 32: 63-69, 1997.
70) 掛地吉弘, 杉町圭蔵: 胃Sm癌の浸潤・転移・再発と生物学的特徴. 胃と腸 32: 57-62, 1997.
71) 表 和彦, 磨伊正義, 溝口雅之・他: 胃Sm癌の細分類とリンパ節転移に関する検討根治的内視鏡的切除術の適応拡大の可能性. 胃と腸 32: 49-55, 1997.
72) 辻 直子, 石黒信吾, 春日井務・他: 胃Sm癌の病理組織学的検討リンパ節転移を指標として. 胃と腸 32: 41-47, 1997.
73) 柳澤昭夫, 宇都出公也, 加藤 洋: 胃癌Sm浸潤の判定と深達度Sm1の考え方. 胃と腸 32: 15-19, 1997.
74) 猪狩 亨, 中村二郎, 滝澤登一郎・他: 胃Sm癌の病理 内視鏡的治療の可能性および根治性の検討. 胃と腸 32: 21- 29, 1997.
75) 大谷吉秀, 大上正裕, 久保田哲朗・他: 早期癌に対する腹腔鏡外科の立場からみた内視鏡的粘膜切除への提言. 胃と腸 31: 1121-1128, 1996.
76) 藤崎順子, 池上雅博, 新井弥生・他: 早期胃癌粘膜切除の適応拡大の限界病理立場から. 胃と腸 31: 1091-1100, 1996.
77) 長南明道, 望月福治, 結城豊彦・他: 早期胃癌の内視鏡的粘膜切除の適応拡大をめぐる現状の問題点遺残再発病変の特徴およびその取り扱い. 胃と腸 31: 1083-1090, 1996.
78) Furue H, Hara Y, Imai Y, et al: Criteria for the evaluation of the clinical effects of solid cancer chemotherapy Japan society for cancer therapy. J. JPn. Soc. Cancer Ther. 28: 101-130, 1993.
80) Cocconi G, DeLisi V, DiBlasio B: Randomized comparison of 5-FU alone or combined with mitomycin and cytarabine (MFC) in the treatment of advanced gastric cancer. Cancer Treat. Rep. 66: 1263-1266, 1982.
84) 仁井谷久暢・他: 5 '-deoxy-5-fluorouridine (5'-DFUR) の各種悪性腫瘍に対する第2相多施設共同研究. 癌と化学療法 12: 2044-2051, 1985.
85) Gastrointestinal Tumor Study Group: Phase II-III chemotherapy studies in advanced gastric cancer. Cancer Treat. Rep. 63: 1871-1883, 1979.
86) Moertel CG, Lavin PT: Phase II-III chemotherapy studies in advanced gastric cancer. Cancer Treat. Rep. 63: 1863-1869, 1979.
91) Aabo K, Pedersen H, Rorth M: Cisplatin in the treatment of advanced gastric carcinoma: a phase II study. Cancer Treat. Rep. 69: 449-450, 1985.
93) Perry MC, Green MR, Mick R, et al: Cisplatin in patients with gastric cancer: a cancer and leukemia group B phase II study. Cancer Treat. Rep. 70: 415-416, 1986.
96) Kelsen DP, Magill R, Cheng E, et al: Phase II trial of etoposide (VP-16) in the treatment of upper gastrointestinal tract malignancies. Cancer Treat. Rep. 67: 509-510, 1983.
97) Futatsuki K, Wakui A, Nakao I, et al: Late phase II study of irinotecan hydrochloride (CPT-11) in advanced gastric cancer. CPT-11 Gastrointestinal Cancer Study Group. JPn. J. Cancer Chemother. 21: 1033-1038, 1994.
99) Einzig AI, Lipsitz S, Wiernik PH, et al: Phase II trial of taxotere in patients with adenocarcinoma of the upper gastrointestinal tract previously untreated with cytotoxic chemotherapy;the Eastern Cooperative Oncology Group (ECOG) results. Proc. Am. Soc. Clin. Oncol. 14: 191 (441) , 1995.
100) Ohtsu A, Sakata Y, Horikoshi N, et al: A phase II study of S-1 in patients with advanced gastric cancer. Proc. Am. Soc. Clin. Oncol. 17: 262, 1998.
101) Kurihara M, Koizumi W, Hasegawa K, et al: Late phase II study of S-1, a novel oral fluoropyrimidine derivative, in patients with advanced gastric cancer. Proc. Am. Soc. Clin. Oncol. 17: 262, 1998.
102) 日本医薬品情報センター編: 医療薬, 日本医薬品集. 薬業時報社, 東京, 1977.
103) 村上 稔・他: 多施設共同研究によるメソトレキセート・5-FU交代療法の進行胃癌および結腸・大腸癌に対するPhase II study. 癌と化学療法 14: 2482-2490, 1987.
109) Cunningham D, Cahn A, Menzies-Gow N: Cisplatin, epirubicin and 5-fluorouracil (CEF) has significant activity in advanced gastric cancer. Proc. Am. Soc. Clin. Oncol. 9: 123, 1990.
110) Caccia G, Alasino C, Fein L: 5-Fluorouracil+epirubicin+cisplatin in patients with advanced gastric cancer. Proc. Am. Soc. Clin. Oncol. 9: 123, 1990.
111) DiLauro L, Capomolla E, Vici P, et al: Cisplatin, epirubicin and fluorouracil (PEF) for advanced measurable gastric carcinoma. Proc. Am. Soc. Clin. Oncol. 14: 206 (503) , 1995.
116) Mabel JA, Little AD: Therapeutic synergism in murine tumors for combinations of cisdichlorodiammine platinum with VP-16-2130r BCNU. Proc. Am. Assoc. Cancer Res. Am. Soc. Oncol. 20: 230, 1979.
117) Seeber S, Osieka R, Schmidt CG, et al: , In vivo resistance towards anthracyclines, etoposide, and cisdiamminedichloroplatinum ( II) . Cancer Res. 67: 4719-4725, 1982.
118) Kelsen DP, Buckner J, Einzig A, et al: Phase II trial of cisplatin and etoposide in adenocarcinomas of the upper gastrointestinal tract. Cancer Treat. Rep. 71: 329-330, 1987.
122) Katz A, Gansl R, Simon S, et al: Phase II trial of VP-16, adriamycin, and cisplatinum in patients with advanced gastric cancer. Proc. Am. Soc. Clin. Oncol. 8: 98, 1989.
123) Taguchi T: Combination chemotherapy with etoposide, adriamycin and cisplatin (EAP) for advanced gastric cancer. Proc. Am. Soc. Clin. Oncol. 8: 108, 1989.
124) Lerner A, Steele GD, Mayer RJ, : Etoposide, doxorubicin, cisplatin for advanced gastric adenocarcinoma: Results of a phase II trial. Proc. Am. Soc. Clin. Oncol. 9: 103, 1990.
125) Wilke H, Preusser P, Fink U, et al: New developments in the treatment of gastric carcinoma. Semin. Oncol. 17: 61-70, 1990.
126) 赤沢修吾, 太田和雄, 栗原 稔・他: 多施設共同研究による l-Leucovorin・5-FU併用療法の進行胃癌に対する後期第 II相試験. J. Jpn. Soc. Cancer Ther. 30: 569-583, 1995.
127) 竹田彬一, 田口鐵男, 太田 潤・他: 多施設共同研究による l-Leucovorin・5-FU併用療法の進行胃癌に対する後期第 II相試験. 癌と化学療法 22: 903-910, 1995.
128) Klein HO: Long-term results with FAMTX (5-fluorouracil, adriamycin, methotrexate) in advanced gastric cancer. Cancer Res. 9: 1025, 1989.
136) Kelsen D, Atiq O, Saltz L, et al: FAMTX (fluorouracil, methotrexate, adriamycin) is as effective and less toxic than EAP (etoposide, adriamycin, cisplatin) : arandom assignment trial in gastric cancer, Proc. Am. Soc. Clin. Oncol. 10: 137, 1991.
137) 佐々木常雄・他: 胃癌に対するメソトレキセート・5-FU交代療法と5-FU単独療法の比較試験-メソトレキセート・ 5-FU交代療法共同Phase III study-. 癌と化学療法 16: 2545-2555, 1989.
139) Wilke H, Wils J, Rougier P, et al: Preliminary analysis of a randomized phase III trial of FAMTX versus ELF versus cisplatin/FU in advanced gastric cancer: atrial of the EORTC gastrointestinal tract cancer cooperative group and the AIO. Proc. Am. Soc. Clin. Oncol. 14: 206 (500) , 1995.
143) Scheithauer W, Kornck G, Zeh B, et al: Palliative chemotherapy versus supportive care in patients with metastatic gastric cancer: randomized trial. (Abstract) Second International Conference on Biology;Prevention and Treatment of GI Malignancy, Koln, Germany, 1995, p. 68.
147) Estrada E, Lacave L, Valle M, et al: Methyl-CCNU, 5-fluorouracil, and adriamycin (MeFA) as adjuvant chemotherapy in gastric cancer. Proc. Soc. Clin. Oncol. 7: 94, 1988.
150) Carrato A, Diaz-Rubio E, Medrano J, et al: Phase III trial of surgery versus adjuvant chemotherapy with mitomycin C and tegafur plus uracil, starting within the first week after surgery, for gastric adenocarcinoma. Proc. Am. Soc. Clin. Oncol. 14: 198, 1995.
152) Nakajima T, Fukami A, Takagi K, et al: Adjuvant chemotherapy with mitomycin C, and with a multi-drug combination of mitomycin C, 5-fluorouracil and cytosine arabinoside after curative resection of gastric cancer. Jpn. J. Clin. Oncol. 10: 187-194, 1980.
153) 今永 一, 中里博昭: 3つのprospective controlled study-その1-. 臨床外科 36: 175-183. 1981.
154) Hattori T, et al: Five-year survival rate of gastric cancer patients treated by gastrectomy, large dose of mitomycin-C, and/or allogeneic bone marrow transplantation. GANN 63: 517-522, 1972.
155) 中島聰線, 梶谷 銀, 深見敦夫・他: 胃ガン治癒手術症例に対するMMC大量短期投与法の遠隔成績. 癌の臨床 22: 21-27, 1976.
157) 山村義孝, 西村美知子, 坂本純一・他: Mitomycin-C, 5-Fluorouracil, OK-432併用による胃癌の補助免疫化学療法. 癌と化学療法 13: 2134-2140, 1986.
158) 藤井雅志, 坂部 孝, 若林和彦・他: 胃癌術後補助化学療法における経口フッ化ピリミジン類の至適投与期間の検討-5-FU錠を用いた手術単独群との比較によるPilot Study-. 癌と化学療法 21: 1199-1208, 1994.
160) Gagliano R, McCracken J, Chen T: Adjuvant chemotherapy with FAM in gastric cancer: aSWOG study. Proc. Am. Soc. Clin. Oncol. 2: 114, 1983.
162) Fisher V, Gunduz N, Saffer E: Influence of the interval between primary tumor removal and chemotherapy on kinetics and growth of metastasis. Cancer Res. 43: 1488-1492, 1983.
165) Markman M: Intraperitoneal chemotherapy for malignant diseases of the gastrointestinal tract. Surg. Gynecol. Obstet. 164: 89-93, 1987.
166) Sugarbaker PH, Cunliffe WJ, Belliveau J, et al: Rationale for integrating early postoperative intraperitoneal chemotherapy into the surgical treatment of gastrointestinal cancer. Semin. Oncol. 16: 83-97, 1989.
168) Schiessel R, Funovics J, Schick B, et al: Adjuvant intraperitoneal cisplatin therapy in patients with operated gastric carcinoma: results of a randomized trial. Acta Med. Austriaca 16: 68-69, 1989.
170) Alexander HR, Buell JF, Fraker DL: Rationale and clinical status of continuous hyperthermic peritoneal perfusion for the treatment of peritoneal carcinomatosis. In: Principles and practice of oncology: PPO updates (eds by DeVita VT, Jr, Hellman S, Rosenberg SA) , JB Lippincott, Philadelphia, 1995, p. 1.
171) Dedrick RL: Theoretical and experimental bases of intraperitoneal chemotherapy. Semin. Oncol. X 11: 1-6, 1985.
173) Los G, Smals OAG, van Vugt MJH, et al: A rationale for carboplatin treatment and abdominal hyperthermia in cancers restricted to the peritoneal cavity. Cancer Res. 52: 1252-1258, 1992.
180) Fujimoto S, Shrestha RD, Kokubun M, et al: Pharmacokinetic analysis of mitomycin C for intraperitoneal hyperthermic perfusion in patients with far-advanced or recurrent gastric cancer. Reg. Cancer Treat. 2: 198, 1989.
181) Gilly FN, Sayag AC, Carry PY, et al: Intraperitoneal chemo-hyperthermic (CHIP) : anew therapy in the treatment of the peritoneal seedings. Int. Surg. 76: 164-167, 1991.
183) Ochiai T, Sato H, et al: Arandomly controlled study of chemotherapy versus chemoimmunotherapy in postoperative gastric cancer patients. Cancer Res. 43: 3001-3007, 1983.
187) Konishi T, Hirata T, Miyama T, et al: Mechanism of synergism and clinical results of sequential methotrexate and 5-fluorouracil in the treatment of gastric cancer. 癌と化学療法 19: 946-953, 1992.
191) Kondo K, Murase M, Yokoyama Y, et al: Neoadjuvant chemotherapy in high-grade advanced gastric cancer with protracted infusional 5-fluorouracil and consecutive low-dose cisplatin. 癌と化学療法 23: 1299-1303, 1996.
193) Kitamura M, Arai K, Iwasaki Y, et al: Leucovorin+5-FU therapy for advanced gastric cancer as a neoadjuvant chemotherapy. 癌と化学療法 22: 2115-2117, 1995.
196) Alexander HR, Grem JL, Hamilton JM, et al: Thymidylate synthase protein expression association with response to neoadjuvant chemotherapy and resection for locally advanced gastric and gastroesophageal adenocarcinoma. Cancer J. Sci. Am. 1: 49, 1995.
205) Gunderson LL, Burch PA, Donohue JH: The role of irradiation as a component of combined modality treatment for gastric cancer. J. Infusional Chemother. 5: 117-124, 1995.
213) Alexander HR, Kelsen DP, Tepper JE: Cancer of the stomach. "Cancer, principles&practice of oncology". 5th ed., J B. Lippincott, Philadelphia, 1997, pp. 1021-1054.
214) Micbel C: Gastric cancer: Radiotherapy and approaches to locally unresectable or recurrent disease. "Gastrointestinal oncology". (Ahlgren ed) , J. B. Lippincott, Philadelphia, 1997, pp. 181-187.
215) Kosaka T, Sejima T, Sugaya J, et al: Radiation therapy for advanced gastric cancer. 癌と化学療法 24: 1701- 1711, 1997.
216) minsky BD: The role of radiation therapy in gastric cancer. Semin. Oncol. 23: 390-396, 1996.
P.1090 掲載の参考文献
1) 胃癌研究会編: 胃癌取扱い規約改訂第12版. 金原出版, 東京, 1993.
2) UICC International Union Against Cancer: TNM CIassification of Malignant Tumours. Fifth Edition (ed. by Sobin LH, Wittekind C) , Wiley-Liss, New York, 1997.
4) Japanese Research Society for Gastric Cancer: Japanese Classification of Gastric Carcinoma. First English Edition. Kanehara Co., Tokyo, 1995.
7) 高木國夫, 岩切啓二, 武長誠三・他: 早期胃癌に対する内視鏡的切除を応用した胃局所切除. 消化器外科 15: 1429-1439, 1992.
10) Wu CC, Chen JT, Chang MC, et al: Optimal surgical strategy for potentially curable serosa-involved gastric carcinoma with intraperitoneal free cancer cells. J. Am. Coll. Surg. 184: 611-617, 1997.
12) 佐野 武, 片井 均, 笹子三津留・他: 早期胃癌の転移: 胃癌研究会から. 胃と腸 32: 809-813, 1997.
17) Neugut AI, Hayek M, Howe G: Epidemiology of gastric cancer. Semin. Oncol. 23: 281-291, 1996.
18) 荒井邦佳, 北村正次, 岩崎善毅: 術後のquality of lifeおよび予後からみた切除不能胃癌に対する空置的胃空腸吻合術の有用性. 日消外会誌 28: 645-649, 1995.
P.1119 掲載の参考文献
1) 大腸癌研究会編: 大腸癌取扱い規約. 改訂第5版. 金原出版, 東京, 1994.
2) TNM classification of malignant tumors: (ed. by Sobin LH, Wittekind Ch) , Fifth Ed,. Wiley-Liss, New York, 1997.
4) 泉本源太郎, 八田昌樹, 西山真一・他: クリアリング法による結腸癌リンパ節転移に関する研究. 日本大腸肛門病会誌 36: 523-531, 1983.
12) Gardner EJ: Follow-up study of a family group exhibiting dominant inheritance for a syndrome including intestinal polyps, osteomas, fibromas and epidermal cysts. Am. J. Hum. Genet. 14: 376-390, 1962.
16) Kussin SZ, Lipkin M, Winawer SJ: lnherited colon cancer;Clinical implications. Am. J. Gastroenterol 72: 443- 457, 1979.
28) Heald RJ, Bussey HJR: Clinical experience at St. Mark’s Hospital with multiple synchronous cancers of the colon and rectum. Dis. Colon Rectum 18: 6, 1975.
31) McMichael AJ, Potter JD: Host factors in carcinogenesis;certain bile-acid metabolic profiles that selectively increase the risk of proximal colon cancer. J. Natl. Cancer. Inst. 75: 185-191, 1985.
43) 加藤知行, 小島 宏, 平井 孝・他: 直腸癌治癒切除後の骨盤腔内局所再発に対する術中の対策. 外科 51: 1328- 1331, 1989.
45) 加藤知行, 近藤三隆, 安井健三・他: 大腸癌患者における術中腹腔細胞診の検討. 日消外会誌 17: 1865-1869, 1984.
46) Moore GE, Sako K, Kondo T, et al: Assessment of the exfoliation of tumor cells into the body cavities. Surg. Gynecol. Obstet. 112: 469-474, 1961.
51) Wolmark N, Fisher B, Wieand HS: The prognostic value of the modifications of the Dukes’Cclass of colorectal cancer. Ann. Surg. 203: 115-122, 1986.
61) 加藤知行, 森本剛史, 渡辺晃祥・他: 若年者の直腸癌. 外科 40: 802-807, 1978.
71) 北條慶一: 一次予防と二次予防;大腸癌. がんの一次予防と二次予防 (市川平三郎, 久道茂編集) , 篠原出版, 東京, 1987, pp. 178-192.
82) 長谷和生, 望月英隆, 吉村一克・他: 直腸癌先進部組織型の臨床的意義に関する検討. 日本大腸肛門病会誌 50: 71- 79, 1997.
83) 滝沢 建: 直腸癌の予後因子に関する病理組織学的研究; 組織型と細胞性間質反応を中心に. 日本大腸肛門病会誌 42: 190-201, 1989.
87) Brown CE, Warren S: Viscera1 metastases from rectal carcinoma. Surg. Gynecol. Obstet. 66: 611-621, 1938.
91) Khankhanian N, Maulight GM, Russel WO, et al: Prognostic significance of vascular invasion in colorectal cancer of Dukes’Bclass. Cancer 39: 1195-1200, 1977.
94) Michelassi F, Vannucci L, Ayala JJ, et al: Local recurrence after curative resection of colorectal adenocarcinoma. Surgery 108: 787-793, 1990.
97) 加藤知行, 森本剛史, 渡辺晃祥・他: 下部直腸癌の局所再発; 特に癌先進部から外科的剥離断端までの距離 (ew) につ いて. 日外会誌 80: 642-650, 1979.
99) 長谷和生, 望月英隆, 宇都宮勝之・他: 大腸癌の浸潤増殖様式 (INF) の予後規定因子としての意義に関する検討. 日本大腸肛門病会誌 49: 463-469, 1996.
100) 諸冨雅之: 進行直腸癌における臨床病理学的研究;術前生検材料からみたリンパ節転移程度の予測. 日外会誌 89: 352-364, 1988.
101) 長谷和生, 望月英隆, 小池聖彦・他: 直腸癌における腫瘍籏出の予後規定因子としての意義に関する検討. 日消外会誌 25: 2765-2772, 1992.
109) Pihl E, Malahy MA, Khankhanian N, et al: Immunomorphological features of prognostic significance in Dukes’class B colorectal carcinoma. Cancer Res. 37: 4145-4149, 1977.
126) 加藤知行, 小島 宏, 平井 孝・他: 大腸癌における術前生検と切除標本の病理組織診断の比較. 癌の臨床 35: 1119- 1122, 1989.
127) 武藤徹一郎, 上谷潤二郎, 沢田俊夫・他: 大腸診断学の歩みと外科. 胃と腸 20: 273-281, 1985.
128) 長谷川かをり, 谷口友章, 野口友義・他: 大腸癌の生検診断における問題点 (第1報) . Gastroenterol. Endosc. 22: 56-60, 1980.
129) 安富正幸: 大腸癌手術における諸問題. 外科治療 47: 199-206, 1982.
130) 武藤徹一郎, 西澤 護, 小平 進・他: 大腸sm癌アンケート集計報告; sm癌の転移リスクファクターを求めて. 胃と腸 26: 911-918, 1991.
131) 加藤知行, 平井 孝: 治療成績からみた大腸早期癌の治療方針; とくにsm癌の治療方針について. 手術 46: 461- 467, 1992.
132) 工藤進英, 曽我 淳, 下田 聡・他: 大腸sm癌のsm浸潤の分析と治療方針. 胃と腸 19: 1349-1356, 1984.
135) 加藤知行, 平井 孝: 結腸癌;進行癌の手術と補助療法. 癌の臨床 40: 1416-1424, 1994.
137) 泉本源太郎, 八田昌樹, 西山真一・他: クリアリング法による結腸癌リンパ節転移に関する研究. 日本大腸肛門病会誌 36: 523-531, 1983.
139) Panettiere FJ, Chen TT: The SWOG large bowel study benefits from therapy. Proc. ASCO 4: 76, 1985.
140) Laurie J, Moertel C, Flemming, et al: Surgical adjuvant therapy of poor prognosis colorectal cancer with levamisole alone or combined levamisole and 5-fluorouracil. Proc. ASCO 5: 81, 1986.
143) Japanese Research Society for Cancer of the Colon and Rectum: Multi-lnstitutional registry of large bowe: cancer in Japan vol 9;cases treated in 1985, 1994.
144) 森谷宜皓: 大腸癌の治療成績は向上したか. CRC 2: 301-310, 1993.
146) 加藤知行, 平井 孝: 腫瘍の局在と進行度からみた手術術式の選択. 消化器外科 13: 289-297, 1990.
147) 高橋 孝, 梶谷 鐶: 直腸癌における側方向リンパ流への転移とその郭清の意義について. 日本大腸肛門病会誌 31: 207-219, 1978.
148) 加藤岳人, 高橋 孝, 太田博俊・他: 直腸癌側方リンパ節転移の検討. 日消外会誌 19: 963-968, 1989.
149) 大見良裕, 大木繁男, 江口英雄・他: 直腸癌のリンパ節転移の特徴;拡大郭清による摘出リンパ節の検討. 日外会誌 81: 676-687, 1980.
150) 白井芳則, 斉藤典男, 布村正夫・他: 直腸癌側方リンパ節転移の態様と治療成績. 日本大腸肛門病会誌 44: 1061- 1066, 1991.
151) 須田武保, 畠山勝義, 岡本春彦・他: 直腸癌における壁内進展. 日本大腸肛門病会誌 45: 421-426, 1992.
152) 小林宣昭: 直腸癌の病理組織学的研究 (第2報) ;特に壁内進展について. 日本大腸肛門病会誌 30: 426-436, 1977.
154) Lazorthes F, Voigt JJ, Roques J, et al: Distal intramural spread of carcinoma of the rectum correlated with lymph nodal involvement. Surg. Gynecol. Obstet. 170: 45-48, 1990.
156) Williams NS, Dixon MF, Johnston D: Reappraisal of the 5 centimetre rule of distal excision for carcinoma of the rectum;Astudy of distal intramural spread and of patient’s survival. Br. J. Surg. 70: 150-154, 1983.
157) 今 充, 森田隆幸, 山中祐治・他: 術後排便機能からみた手術術式の選択. 消化器外科 17: 307-314, 1990.
158) 畠山勝義, 島村公年, 須田武保・他: 下部直腸癌に対するJ型結腸嚢肛門吻合術. 消化器外科 17: 301-306, 1994.
164) Grinnell RS: Results of ligation of inferior messenteric artery at the aorta in resections of carcinoma of the descending and sigmoid colon and rectum. Surg. Gynecol. Obstet. 120: 1031-1036, 1965.
170) 小山靖夫: 直腸癌における拡大根治手術. 外科治療 36: 41-45, 1977.
171) 加藤知行, 平井 孝: 下部直腸癌における側方リンパ節郭清の意義と問題点;側方リンパ節群の範囲の同定を中心に. 消化器癌 3: 65-71, 1993.
172) 小林宣昭: 下部進行直腸癌に対する側方郭清の意義と問題点. 消化器癌 3: 357-363, 1993.
174) 加藤知行, 平井 孝, 小寺泰弘・他: 下部直腸癌における拡大リンパ節郭清の功罪. 日消外会誌 28: 903-907, 1995.
175) 加藤知行, 小平 進: 直腸癌・長期予後とQOLからみた神経温存手術の適応. 日臨外医会誌 56: 1079-1087, 1995.
180) 加藤知行, 平井 孝: 局所進行直腸癌に対する骨盤内臓器全摘術. 医学のあゆみ 172: 693-696, 1995.
181) Lopez MJ, Monafo WW: Role of extended resection in the initial treatment of locally advanced colorectal carcinoma. Surgery 113: 365-372, 1993.
191) 加藤清司: 腹腔鏡手術における麻酔管理上の問題点. 日外科系連会誌 20: 377-380, 1995.
196) Ota DM: Laparoscopic resection for colon cancer;Afavorable view. Important Adv Oncol. Lippincott-Raven, Philadelphia, 1996, pp. 227-229.
199) Cirocco WC, Schwartzman A, Golub RW: Abdominal wall recurrence after laparoscopic colectomy for colon cancer. Surgery 116: 842-846, 1994.
206) Abdi E, Harbora D, Hanson J, et al: Adjuvant chemoimmuno-and immuno-therapy in stage B 2 and C colorectal cancer. Proc. Am, Soc. Clin. Oncol. 6: 93, 1987.
207) Sertori MR, Guarneri D, Rubagotti A, et al: Adjuvant chemotherapy and immunochemotherapy in colorectal cancer Dukes’C. Oncology 44: 78-81, 1987.
212) 安富正幸, 北條慶一, 土屋周二: KW-2299の結腸癌治癒切除例に対する臨床試験. 日癌治療会誌 31: 819, 1996.
213) Wolmark N., Bryant J., Hyams DM, et al: The relative efficacy of 5-FU+leucovorin (FU-LV) and 5-FULV+interferon alfa-2 a (IFN) in patients with Dukes 'B and C carcinoma of the colon;First report of NSABP C-05. Proc. Am. Soc. Clin. Oncol. 17: 255 a, 1998.
214) Haller DG., Catalano PJ., Macdonald JS.: Fluorouracil (FU) , leucovorin (LV) and levamisole (LEV) adjuvant therapy for colon cancer;five-year final report of INT-0089. Proc. Am. Soc. Clin. Oncol. 17: 256 a, 1998.
215) Kato T, Nakazato H: Surgical adjuvant chemotherapy for colorectal cancer. Cancer chemotherapy;Challenges for the future. Excerpta Medica, Amsterdum, 1986, pp. 250-259.
216) 北條慶一, 梶谷環: 大腸癌の補助化学療法 (梶谷班一次方式) の成績. 癌と化学療法 13: 3063-3073, 1986.
217) 松田泰次, 安富正幸, 菊池金男・他: 共同研究による大腸癌手術のINTENSIVE ADJUVANT CHEMOTHERAPY の検討 (第3報) ; 術後5年成績について. 癌と化学療法 18: 461-469, 1991.
219) 西田修, 内野純一, 菊池金男・他: 共同研究による大腸癌の術後補助化学療法の検討; 第2次研究 (第3報) 治癒切除例の術後5年成績について. 癌と化学療法 20: 101-108, 1993.
220) がん集学的治療研究財団: 特定研究7; 大腸癌術後補助化学療法としてのフッ化ピリミジン系抗癌剤の有用性に関する臨床比較試験・研究報告書. 1996.
221) Nakazato H., Koike A., Sail L., et al: Efficacy of oral UFT as adjuvant chemotherapy to curative resection of colorectal cancer;aprospective randomized clinical trial. Proc. Am. Soc. Clin. Oncol. 16: 279 a, 1997.
222) Espinosa E., Gonzalez Baron M., Feliu J., et al: UFT-leucovorin as adjuvant treatment for Dukes’B 2-C colon cancer. Proc. Am. Soc. Clin. Oncol. 17: 275 a, 1998.
226) Metzger U, Laffer U, Castiglione M, et al: Adjuvant intraportal chemotherapy for colorectal cancer;4year results of the randomized Swiss study. Proc. Am. Soc. Clin. Oncol. 8: 105, 1989.
228) Wolmark N, Rockette H, Wiokerham D, et al: Adjuvant therapy of Dukes’A, B, and C adenocarcinoma of the colon with portal-vein fluorouracil hepain infusion. Preliminary results of national surgical adjuvant breast and bowel project protocol C-02. J. Clin. Oncol. 8: 1466-1475, 1990.
229) Laffer U., Maibach R., Metzger U., et al: Randomized trail of adjuvant perioperative chemotherapy in radically resected colorectal cancer (SAKK 40/87) . Proc. Am. Soc. Clin. Oncol. 17: 256 a, 1998.
230) Piedbois P, Buyse M, Gray R, et al: Vein infusion is an effective adjuvant treatment for patients with colorectal cancer. Proc. Am. Soc. Clin. Oncol. 14: 192, 1995.
233) Stearns MW, Deddish MR, Quan SH: Preoperative roentgen therapy for cancer of the rectum. Surg. Gynecol. Obstet. 109: 225-229, 1959.
234) Stearns MW, Deddish MR, Quan SH: Preoperative roentgen therapy for cancer of the rectum and rectosigmoid. Surg. Gynecol. Obstet. 138: 584-589, 1974.
238) Rider WD, Palmer JA, Mahoney LJ, et al: Preoperative irradiation in operable cancer of the rectum;Report of the Tront trial. Can. J. Surg. 20: 335-338, 1977.
240) Second report of an MRC working party. The evaluation of low dose preoperative X-ray therapy in the management of operable rectal cancer;Results of a randomely controlled trial. Br. J. Surg. 71: 21-25, 1984.
242) 木村幸三郎, 山本啓一郎, 花輪聡・他: 進行直腸癌に対する放射線療法. 消外 6: 695-699, 1983.
243) 木村幸三郎, 中島厚, 勝又健次・他: 局所再発予防のための補助療法; 放射線療法を中心として. 消外 13: 343-351, 1990.
244) Ahmad N R, Anne PR, Nagle DA, et al: Preoperative chemoradiation therapy appears superior to preoperative radiation alone in the management of clinical T 3/T 4 rectal cancer, Proc. Am. Soc. Clin. Oncol. 16: 256 a, 1997.
245) Maghfoor I, Wilkes J, Kuvshinoff B, et al: Neoadjuvant chemoradiotherapy with sphincter-sparing surgery for low lying rectal cancer. Proc. Am. Soc. Clin. Oncol. 16: 274 a, 1997.
246) Janjan NA, Khoo VS, Rich TA, et al: Magnitude of responce to preoperative chemoradiation;prognostic implication in patients with locally advanced rectal cancer. Proc. Am. Soc. Clin. Oncol. 16: 273 a, 1997.
250) Gunderson LL, Cohen AM, Dosoretz DE, et al: Residual, unresectable, or recurrent colorecatl cancer;External beam irradiation and intraoperative electron beam boost±resection. Int. J. Radiat. Oncol. Biol. Phys. 9: 1597- 1609, 1983.
259) Weaver D, Lindblad AS: Radiation therapy and 5-fluorouracil (5-FU) with or without MeCCNU for the treatment of patients with surgically adjuvant adenocarcinoma of the rectum. Proc. Am. Soc. Clin. Oncol. 9: 106, 1990.
260) 0’connel M, Wieand H, Krook J, et al: Lack of value for methyl-CCNU (MeCCNU) as a component of effective rectal cancer surgical adjuvant therapy;Interimanalysis of intergroup protocol 86-47-51. Proc. Am. Soc. Clin. Oncol. 10: 134, 1991.
268) 加藤知行, 坂本純一, 安井健三・他: 直腸癌手術後の局所再発の診断と治療. 日消外会誌 20: 2584-2592, 1987.
271) 加藤知行, 平井 孝, 荒井保明: 直腸癌局所再発の治療. 消化器外科 17: 317-324, 1994.
276) Welch JP, Donaldson GA: The clinical correlation of an autopsy study of recurrent colorectal cancer. Ann. Surg. 189: 496-502, 1979.
279) 森 武生: 骨盤内臓器全摘術の改良と成績. 手術 43: 1735-1744, 1989.
282) 小林宣昭, 杉原健一, 赤須孝之・他: 骨盤内臓全摘術; 適応と手技の要点. 消化器外科 17: 307-314, 1994.
286) Jaffe BM, Donegman WL, Watson F, et al: Factors influencing survival in patients with untreated hepatic metastases. Surg. Gynecol. Obstet. 127: 1-11, 1968.
288) 太田博俊, 西 満正, 堀 雅晴・他: 大腸癌肝転移に対する治療とその成績. 消化器外科 16: 1641-1651, 1993.
289) Wood CB, Gillis CR, Blumgart LH: Aretrospective study of the natural history of patients with liver metastases from colorectal cancer. Clin. Oncol. 2: 285-288, 1976.
290) 山崎 晋, 長谷川博, 幕内雅敏: 転移性肝腫瘍に対する肝切除の意義と限界. 外科治療 52: 241-247, 1985.
291) 安井健三, 加藤知行: 大腸癌肝転移に対する肝切除の適応と系統的肝切除術. 消化器外科 16: 1693-1699, 1993.
293) Scheele J, Stangle R, altendorf-Hofmann A, et al: Indications of prognosis after hepatic resection for colorectal secondaries. Surgery 110: 13-29, 1991.
294) 杉原健一, 北條慶一, 小林宣昭・他: 大腸癌肝転移の外科治療. 日消外会誌 24: 1147-1151, 1991.
299) Weinerman B, Shah A, Fields A, et al: Arandomized trial of continuous systemic infusion versus bolus therapy 5-fluorouracil in metastatic measurable colorectal cancer. Proc. Am. Soc. Clin. Oncol. 10: 143, 1990.
301) Harris BE, Song R, Soong S, et al: Relationship between dihydrophyrimidine dehydrogrnase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patiens receiving 5-fluorouracil by protracted continuous infusion. Cancer Res. 50: 197-201, 1990.
309) Gupta E, Lestingi TM, Mick R, et al: Metabolic fate of irinotecan in humans: correlation of glucuronidation with diarrhea. Cancer Res, 54: 3723-3725, 1994.
312) Pitot HC, Wender DB, 0’Connell MJ, et al: A phase II trial of irinotecan in patients with metastatic colorectal carcinoma. J. Clin. Oncol. 15: 2910-2919, 1997.
318) Bertino JR, Sawicki WL, Lindquist CA, et al: Schedule-dependent antitumor effects of methotrexate and 5-fluorouracil. Cancer Res. 37: 327-328, 1977.
319) Houghton JA, Maroda SJ Jr. Phillips JO, et al: Biochemical determinants of responsiveness to 5-fluorouracil and its derivatives in xenografts of human colorectal adenocarcinomas in mice. Cancer Res. 41: 144-149, 1981.
326) Poon MA, 0’Connell MJ, Moertel CG, et al: Biochemical modulation of fluorouracil: evidence significant improvement of survival and quality of life in patients with advanced colorectal carcinora. J. Clin. Oncol. 7: 1407-1418, 1989.
331) Poon MA, 0’Connell MJ, Wieand HS, et al: Biochemical moduration of fluorouracil with leucovorin: confirmatory evidence of improved therapeutic efficacy in advanced colorectal cancer. J. Clin. Oncol. 9: 1967-1972, 1991.
P.1144 掲載の参考文献
1) 日本肝癌研究会: 原発性肝癌に関する追跡調査-第11報-. 肝臓 36: 208-218, 1995.
2) 日本肝癌研究会編: 原発性肝癌取扱い規約. (第3版) , 金原出版, 東京, 1992.
3) 山崎 晉, 長谷川博, 幕内雅敏: 最小肝癌の臨床病理学的分析と, それに基づく新しい概念の切除法-27切除例の検討肝臓 22: 1714-1724, 1981.
4) Okazaki N, Yoshida T, Yoshino M, et al: Screening of patients with chronic liver disease for hepatocellular carcinoma by ultrasonography. Clin. Oncol. 10: 241-246, 1984.
18) Sato M, Watanabe Y, Lee T, et al: Well-differentiated hepatocellular carcinoma: clinicopathological features and results of hepatic resection. Am. J. Gastroenterol. 90: 112-116, 1995.
21) 原発性肝がんの病態に応じた治療方針の選択に関する研究, 厚生省平成3年度対がん10ヵ年総合戦略プロジェクト研究報告書. 1992, pp. 151-155.
22) 原発性肝がんの病態に応じた治療方針の選択に関する研究, 厚生省平成5年度対がん10ヵ年総合戦略プロジェクト研究報告書. 1996, pp. 176-181.
23) Gozzetti G, Mazziotti A, Cavallari A, et al: Clinical experience with hepatic resections for hepatocellular carcinoma in patients with cirrhosis. Surg. Gynecol. Obstet. 166: 503-510, 1988.
26) Tsuzuki T, Sugioka A, Ueda M, et al: Hepatic resection for hepatocellular carcinoma. Surgery 107: 511-520, 1990.
27) Sasaki Y, Imaoka S, Masutani S, et al: Influence of coexisting cirrhosis on long-term prognosis after surgery in patients with hepatocellular carcinoma. Surgery 112: 515-521, 1992.
28) Chen PJ, Chen DS, Lai MY, et al: Clonal origin of recurrent hepatocellular carcinoma. Gastroenterology 87: 1514-1519, 1990.
31) Oda T, Tsuda H, Sakamoto M, et al: Mutation pattern of the p 53 gene as a diagnostic marker for multiple hepatocellular carcinoma. Cancer Res. 52: 3674-3678, 1992.
32) Tsuda H, Oda T, Sakamoto M, et al: Different pattern of chromosomal alle loss in multiple hepatocellular carcinoma as evidence of their multifocal origin. Cancer Res. 52: 1504-1509, 1992.
33) Esumi M, Aritaka T: Clonal origin of human hepatoma determined by integration of hepatitis virus DNA. Cancer Res. 46: 5767-5771, 1986.
36) 池田健次: 肝癌の外科切除と再発. 肝細胞癌の予知, 診断, 治療. 第1版, メジカルビュー社, 大阪, 1995, pp. 48- 66.
39) 岩本伸一, 佐々木洋, 今岡真義・他: Stage IV肝細胞癌に対する肝切除の意義. 日消外会誌 25: 2118-2122, 1992.
40) 佐々木洋, 今岡真義, 岩本伸一・他: Stage IV肝細胞癌に対する肝切除の意義とその適応-TAE治療との比較検討-. 日外会誌 93: 1107-1110, 1992.
42) Sasaki Y, Imaoka S, Shibata T, et al: Decollateralization with silicone rubber sheeting for advanced hepatoce1-lular carcinoma: apreliminary report. Surgery 108: 840-846, 1990.
46) 泉 良平, 小林弘信, 谷屋隆雄・他: 肝細胞癌の再発例の検討. 日消外会誌 21: 831-835, 1988.
56) 渡辺 心: モノクロナール抗体Ki-67を用いたフローサイトメトリーによる原発性肝細胞癌増殖活性の検討. 日外会誌 96: 439-447, 1995.
58) 岩本伸一, 石黒信吾, 佐々木洋・他: 肝細胞癌の病理学的悪性度とcadherin. 病理と臨床 12: 1859-1865, 1993.
59) Hsu HC, Tseng HJ, Lai PL, et al: Expression of p 53 gene in 184 unifocal hepatocellular carcinomas: association with tumor growth and invasiveness. Cancer Res. 53: 4691-4694, 1993.
62) Nagasue N, Yukawa H, Chang YU, et al: Assessment of pattern and treatment of intrahepatic recurrence after resection of hepatocellular carcinoma. Surg. Gynecol. Obstet. 171: 217-222, 1990.
66) 佐々木洋, 今岡真義, 中野博史・他: 肝細胞癌の残肝再発と遠隔転移に対する外科的治療. 消化器病・UP TO DATE (consensus & controversies, 1996) (小林絢三編) , 永井書店, 大阪, 1997, pp. 58-63.
67) Shimada M, Matsumata, Taketomi A, et al: Repeated hepatectomy for recurrent hepatocellular carcinoma. Surgery 115: 703-706, 1994.
68) Suenaga M, Sugiura H, Kokubo Y, et al: Repeated hepatic resection for recurrent hepatocellular carcinoma in eighteen cases. Surgery 115: 452-457, 1994.
69) Kakazu T, Makuuchi M, Kawasaki S, et al: Repeat hepatic resection for recurrent hepatocellular carcinoma. Hepatogastroenterology 40: 337-341, 1993.
71) Ohto M, Ebara M, Watanabe Y, et al: Percutaneous ethanol injection therapy (PEI) for small hepatocellular carcinoma. Evaluation of its utility on the basis of tumor-image and survival after therapy. JPn. J. Med. Imaging 7: 25-33, 1988.
74) 北 和彦, 江原正明, 杉浦信之・他: 小肝細胞癌に対する経皮的エタノール注入療法 (PEI) -長期観察に基づく抗腫瘍効果と予後の検討-. 日消病誌 91: 1949-1955, 1994.
75) Tanikawa K, Majima Y: Percutaneous ethanol injection therapy for recurrent hepatocellular carcinoma. Hepatogastroenterology 40: 324-327, 1993.
76) 池田健次: 肝細胞癌に対するエタノール局注療法. 肝細胞癌の予知, 診断, 治療. 第1版, メジカルビュー社, 大阪, 1995, pp. 67-83.
79) Breedis C, Yong G: The blood supply of neoplasms in the liver. Am. J. Pathol. 30: 969-985, 1954.
85) 打田日出夫, 大石 元: Interventional angiography: embolizationの基本事項. 治療 68: 699-702, 1986.
90) Groupe D’Etude et de traitement du carcinome hepatocellulaire: Acomparison of lipiodol chemoembolization and conservative treatment for unresectable hepatocellular carcinoma. N. Engl. J. Med. 332: 1256-1261, 1995.
92) 柴田 高, 佐々木洋, 今岡真義・他: 肝細胞癌に対するリピオドール, シスプラチンサンドイッチ療法の抗腫瘍効果と遠隔成績. 日外会誌 91: 859-863, 1989.
94) 池田健次, 村島直哉, 竹内和男・他: 肝癌に対する動脈塞栓術後の肝動脈主幹部閉塞と肝動脈spasmとの関連について. 肝臓 25: 1153-1159, 1984.
96) Saitsu H, Maeda Y, Tanikawa S, et al: Investigation of microwave coagulo-necrotic therapy for 21 patients with small hepatocellular carcinoma less than 5 cm in diameter. J. Jpn. Surg. Soc. 94: 359-365, 1993.
98) 佐々木洋, 今岡真義, 中野博史・他: 寄生栄養動脈の発達によるTAE無効再発肝細胞癌に対する開胸下マイクロ波凝固療法. 癌と化学療法 24: 1647-1650, 1997.
100) 才津秀樹, 吉田 正, 大堂雅晴・他: 5cm以下の肝細胞癌に対するマイクロ波凝固壊死療法 (MCN) について. 臨床外科 49: 309-315, 1994.
105) 山崎 晉, 山本順司: 肝内胆管癌: 新しい肉眼分類. 肝胆膵 30: 480-484, 1995.
106) 杉浦信之, 甲島洋平, 真田昌彦・他: 肝内胆管癌: 画像診断. 肝胆膵 30: 459-468, 1995.
108) 篠原靖志, 竜 崇正, 渋谷幸喜・他: 胆管造影CT三次元イメージングによる肝内胆管枝の描出. 日本臨牀 49: 1893- 1897, 1991.
110) 北野 悟, 広橋伸治, 打田日出夫・他: 胆管細胞癌のMRI, 特に造影MRIの有用性. 日磁医誌 12: 237-244, 1992.
112) Kawarada Y, Mizumoto R: Diagnosis and treatment of cholangiocellular carcinoma of the liver. Hepatogastroenterology 37: 176-181, 1990.
P.1158 掲載の参考文献
3) 厚生省大臣官房統計情報部: 平成6年人口動態統計, 東京, 1996, pp. 274-277.
4) Japanese Cancer Association: Cancer mortality and morbidity statistics. Japan and the world-1994. Japan Scientific Societies Press, Tokyo, 1994, pp. 186-187.
13) Silverman DT, Brown LM, Hoover RN, et al: alcohol and pancreatic cancer in blacks and whites in the United States. Cancer Res. 55: 4899-4905, 1995.
15) 斉藤洋一: 膵癌全国登録調査報告. 膵臓 11: 479-506, 1996.
16) 日本膵臓学会編: 膵癌取扱い規約. 第4版, 金原出版, 東京, 1993.
21) Tada M, Omata M, Kawai S, et al: Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma. Cancer Res. 53: 2472-2474, 1993.
28) Hiyama E, Kodama T, Shinbara K, et al: Telomerase activity is detected in pancreatic cancer but not in benign tumors. Cancer Res. 57: 1326-1333, 1997.
30) 日本癌治療学会固形がん化学療法効果判定基準. 日癌治療会誌 21: 929-942, 1986.
31) 膵癌の治療効果判定基準 (案) . 膵臓 7: 107-121, 1992.
32) Aoki K, Okada S, Moriyama N, et al: Accuracy of computed tomography in determining pancreatic cancer tumor size. Jpn. J. Clin. Oncol. 24: 85-87, 1994.
33) Ishii H, Okada S, Okusaka T, et al: CA 19-9 in evaluating the response to chemotherapy in advanced pancreatic cancer. Hepatogastroenterology 44: 279-283, 1997.
58) Moore M, Andersen J, Burris H, et al: Arandomized trial of gemcitabine (GEM) versus 5-FU as first-line therapy in advanced pancreatic cancer. Proc. ASCO 14: 199, 1995.
62) Hubbard KP, Pazdur R, Ajani JA, et al: Phase II evaluation of iproplatin in patients with advanced gastric and pancreatic cancer. Am. J. Clin. Oncol. 15: 524-527, 1992.
65) CPT-11 Study Group on Gastrointestinal Cancer: alate phase II study of CPT-11, irinotecan hydrochloride, in patients with advanced pancreatic cancer. Jpn. J. Cancer Chemother. 21: 1039-1046, 1994.
71) Moertel CG, Rubin J, 0’Connell MJ, et al: Aphase II study of combined 5-fluorouracil, doxorubicin, and cisplatin in the treatment of advanced upper gastrointestinal adenocarcinomas. J. Clin. Oncol. 4: 1053-1057, 1986.
88) Nagasu T, Yoshimatsu K, Rowell C, et al: Inhibition of human tumor xenograft growth by treatment with the farnesyl transferase inhibitor B 956. Cancer Res. 55: 5310-5314, 1995.
89) Aoki K, Yoshida T, Sugimura T, et al: Liposome-mediated in vivo gene transfer of antisense K-ras contruct inhibits pancreatic tumor dissemination in the murine peritoneal cavity. Cancer Res. 55: 3810-3816, 1995.
P.1168 掲載の参考文献
2) Traverso WL, Longmire WP Jr: Preservation of the pylorus in pancreaticoduodenectomy. Surg. Gynecol. Obstet. 146: 959-962, 1978.
6) 日本膵臓学会編: 膵癌取扱い規約. 第4版, 金原出版, 東京, 1993.
7) Sobin LH, Wittekind Ch (eds) . UICC: TNM classification of malignant tumours. 5th ed, Wiley-Liss, New York, 1997.
8) Fortner JG: Regional resection of cancer of the pancreas: anew surgical approach. Surgery 73: 307-320, 1973.
10) Gudjonsson B: Carcinoma of the pancreas: critical analysis of costs, results of resections, and the need for standardized reporting. J. Am. Coll. Surg. 181: 483-503, 1995.
11) 斎藤洋一: 膵癌全国登録調査報告. 膵臓 11: 479-506, 1996.
14) Lygidakis NJ, Stringaris K: Adjuvant therapy following pancreatic resection for pancreatic duct carcinoma: aprospective randomized study. Hepatogastroenterology 43: 671-680, 1996.
P.1184 掲載の参考文献
1) 厚生省大臣官房統計情報部: 昭和25年-平成7年人口動態統計. 厚生統計協会, 1995.
2) 富永佑民, 青木國雄, 花井 彩・他 (編) : 癌統計白書, 篠原出版, 東京, 1993.
3) 日本胆道外科研究会, 胆道癌登録事務局 (編) : 全国胆道癌登録調査報告, 1996年度症例, 1997.
4) 日本胆道外科研究会 (編) : 胆道癌取扱い規約, 第4版, 金原出版, 東京, 1997.
5) 二村雄次, 早川直和, 豊田澄夫・他: 経皮経肝胆道内視鏡. 胃と腸 16: 681-689, 1981.
6) 二村雄次, 神谷順一, 早川直和・他: PTCSによる表層拡大型胆管癌の診断. 腹部画像診断 6: 333-345, 1986.
9) 乾 和郎, 中沢三郎, 芳野純治・他: 胆管内超音波検査による胆管癌の深達度診断. 胆と膵 15: 1037-1041, 1994.
10) Tamada K, Ido K, Ueno N, et al: Preoperative staging of extrahepatic bile duct cancer with intraductal ultrasonography. Am. J. Gastroenterol. 90: 239-246, 1995.
12) 坂本英至, 二村雄次, 神谷順一・他: 肝門部胆管癌に対する胆管上流側切除範囲-PTBD造影およびPTCSによる進展範囲診断-. 日消外会誌 30: 2069-2073, 1997.
14) 權 雅憲: ヘリカル (スパイラル) CTによる胆道癌の診断の動向-血管, 膵浸潤について-. 胆と膵 18: 729-738, 1997.
16) 崔 仁煥, 有山 襄, 須山正文・他: 胆道癌の早期診断におけるMRCPの有用性. 胆と膵 18: 721-727, 1997.
21) 上坂克彦, 二村雄次, 早川直和・他: 下部胆管癌に対する幽門輪温存膵頭十二指腸切除術の適応-臨床病理学的検討-. 日消外会誌 26: 1233-1238, 1993.
22) 山田康夫, 山内英生, 柿崎健二: 中下部胆管癌の予後因子の検討-特に核DNA量, MIB-1 score, p 53蛋白発現について-. 日消外会誌 30: 2265-2273, 1997.
23) Hadjis NS, Blenkharn JI, alexander N, et al: Outcome of radical surgery in hilar cholangiocarcinoma. Surgery 1O7: 597-604, 1990.
28) 梛野正人, 二村雄次, 神谷順一・他: 膵・胆道癌に対する門脈合併切除. 静脈学 4: 63-69, 1993.
29) Tashiro S, Uchino R, Hiraoka T, et al: Surgical indication and significance of portal vein resection in biliary and pancreatic cancer. Surgery 109: 481-487, 1991.
30) Nimura Y, Hayakawa N, Kamiya J, et al: Hepatopancreatoduodenectomy for advanced carcinoma of the biliary tract. Hepatogastroenterology 38: 170-175, 1991.
39) 神谷順一, 二村雄次, 早川直和・他: 経皮経肝胆道鏡 (PTCS) によるT-tubeを用いた胆汁内瘻術. 胆道 3: 106-111, 1989.
40) 広岡芳樹, 後藤秀実, 伊藤彰浩・他: カラードプラ断層法による胆嚢疾患の診断. 胆と膵 18: 739-745, 1997.
44) 浅田康行, 三浦将司, 三井 毅・他: 胆嚢癌の病理学的予後規定因子. とくにss胆嚢癌についての検討. 日臨外医会誌 57: 2390-2396, 1996.
46) 二村雄次, 早川直和, 神谷順一・他: Stage IV胆嚢癌に対する拡大手術の意義. 日外会誌 88: 1343-1346, 1987.
47) 吉川達也: 高度進行癌の外科治療. 日消外会誌 30: 1895-1899, 1997.
49) 須山政文, 有山 襄, 佐藤一弘・他: 経皮経肝胆管内瘻術 (PTBE) による悪性胆管狭窄の治療. 胆と膵 18: 515-519, 1997,
50) 福田秀一, 奥田康司, 木下壽文・他: 胆道癌に対する5-FU, CDDP少量持続肝動注療法の有用性. 胆道 10: 333-340, 1996.
53) 安田健治朗, 中島正継, 趙 栄済・他: 十二指腸乳頭部癌の診断, EUSの立場から. 胃と腸 32: 151-156, 1997.
54) 宮崎 亮, 池田靖洋, 岩永真一・他: 十二指腸乳頭部癌の外科治療, 幽門輪温存膵頭十二指腸切除術を中心に. 胃と腸 32: 173-179, 1997.
61) 古川 剛, 大橋計彦, 栗本組子・他: 内視鏡的に切除しえた径35mmの十二指腸乳頭部腺腫の1例. Gastroenterol. Endosc. 38: 2201-2206, 1996.
62) 真口宏介, 柳川伸幸, 須賀俊博・他: 十二指腸乳頭部の内視鏡的治療の現状, 内視鏡的乳頭部腫瘍切除術を施行した1例. 胃と腸 32: 182-185, 1997.
P.1199 掲載の参考文献
1) Linehan WM, Shipley WU, Parkinson DR: Cancer of the kidney and ureter. In DeVita VT, Hellman S, Rosenberg SA (eds) : Cancer-Principles and practice of oncology (4th edition) . Philadelphia, JB Lippincott, 1993, pp. 1023-1051.
4) 厚生統計協会: 国民衛生の動向 厚生の指標. 42 (臨時増刊) : 429-430, 1996.
5) 富永裕民, 青木国雄, 花井 彩・他: がん統計白書-罹患/死亡/予後-1993. 篠原出版, 東京, 1993.
6) McLaughlin JK, Mandel JS, Blot WJ, et al: Apopulation-based case-control study of renal cell carcinoma. JNCI 72: 275-284, 1984.
7) Yu MC, Mack TM, Hanish R, et al: Cigarette, obesity, diuretic use, and coffee consumption as risk factors for renal cell carcinoma. JNCI 77: 351-356, 1986.
17) 八尾正裕, 執印太郎: 家族性腎癌. 癌の臨床 42: 1215-1223, 1996.
18) Glenn GM, Choyke PL, Zbar B, et al: von Hippel-Lindau disease: clinical review and molecular genetics. Probl. Urol. 4: 312-330, 1990.
22) Shuin T, Kondo K, Torigoe S, et al: Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau disease tumor suppressor gene in primary human renal cell carcinomas. Cancer Res. 54: 2852-2855, 1994.
29) Oda H, Nakatsuru Y, Ishikawa T: Mutation of the p 53 gene and p 53 protein overexpression are associated with sarcomatoid transformation in renal cell cancer. Cancer Res. 55: 658-662, 1995.
31) Atlas I, Mendelsohn J, Baselga J, et al: Growth regulation of human renal carcinoma cells: role of transforming growth factora. Cancer Res. 52: 3335-3339, 1992.
33) Blay JY, Negrier S, Combaret V, et al: Serum level of interleukin 6 as a prognosis factor in metastatic renal cell carcinoma. Cancer Res. 52: 3317-3322, 1992.
37) Takahashi A, Sasaki H, Kim SJ, et al: Markedly increased amounts of messenger RNAs for vascular endothelial growth factor and placenta growth factor in renal cell carcinoma associated with angiogenesis. Cancer Res. 54: 4223-4237, 1994.
40) 日本泌尿器科学会他編: 腎癌取扱い規約 (第2版) , 金原出版, 東京, 1992.
45) 三原修一: 超音波検診における腎細胞癌の早期発見. 日本内科超音波学会誌 20: 24-32, 1993.
51) 伊野宮秀志, 井坂茂夫, 岡野達弥・他: 転移のない腎細胞癌の予後因子解析. 日泌尿会誌 87: 1099-1104, 1996.
53) 里見佳昭: 腎癌の予後に関する臨床的研究-特に生体側の因子を中心に-. 日泌尿会誌 64: 195-216, 1973.
54) 里見佳昭: 腎癌の治療の現況と今後の課題. 日泌尿会誌 81: 1-13, 1990.
55) 大西哲朗, 大石幸彦, 増田富士男・他: 腎摘施行Stage4 B腎細胞癌の予後を左右する因子. 日泌尿会誌 85: 1664- 1672, 1994.
57) 塚本泰司: 腎細胞癌の浸潤転移と血管新生. 日泌尿会誌 87: 1-12, 1996.
61) Shimazui T, Oosterwijk E, Debruyne MJ, et al: Molecular prognostic factor in renal cell carcinoma. Semin. Urol. (Oncol. 14: 250-255, 1996.
73) Whang M, 0’toole K, Bixon R, et al: The incidence of multifocal renal cell carcinoma in patients who are candidates for partial nephrectomy. J. Urol. 154: 968-971, 1995.
80) 大園誠一郎, 岡島英五郎, 平尾佳彦: 進行癌に対する拡大手術. 癌の臨床 42: 1241-1263, 1996.
84) Yagoda A, Abi-Rached B, Petrylak D: Chemotherapy for renal-cell carcinoma: 1983-1993. Semin. Oncol. 22: 42-60, 1995.
85) Stahl M, Wilke HJ, Seeber S, et al: Cytokines and cytotoxic agents in renal cell carcinoma: Areview. Semin. Oncol. 19 (Suppl. 4) : 70-79, 1992.
86) 里美佳昭, 福田百邦: 腎癌治療の最前線-免疫療法. 癌の臨床 42: 1251-1264, 1996.
87) Wirth MP: Immunotherapy for metastatic renal cell carcinoma. Urol. Clin. North Am. 20: 283-295, 1993.
88) 丸茂 健, 早川正道, 村井 勝: 進行腎細胞癌に対するヒト型インターフェロンの抗腫瘍効果とその免疫学的検討. 日泌尿会誌 76: 965-973, 1985.
89) 大西哲朗, 大石幸彦, 飯塚典男: 進行性腎細胞癌の生存率に関するインターフェロン療法の効果に関する検討. 日泌尿会誌 88: 463-472, 1997.
93) Stadler WM, Vogelzang NJ: Low-dose interleukin-2 in the treatment of metastatic renal-cell carcinoma. Semin. Oncol. 22: 67-73, 1995.
94) Wadler S, Schwartz EL: Antineoplastic activity of the combination of interferon and cytotoxic agents against experimental and human malignancy: areview. Cancer Res. 50: 3473-3486, 1990.
96) Pierce WC, Belldegrun A, Figlin RA: Cellular therapy: scientific rationale and clinical results in the treatment of metastatic renal-cell carcinoma. Semin. Oncol. 22: 74-80, 1995.
98) Simons JW, Jaffee EM, Weber CE, et al: Bioactivity of autologous irradiated renal cell carcinoma vaccines generated by ex vivo granulocyte-macrophage colony-stimulating factor gene transfer. Cancer Res. 57: 1537-1546, 1997.
101) 沖 明典, 大野忠夫: 癌治療における細胞療法の現状と今後の展望: 養子免疫療法を中心として. バイオサイエンスとインダストリー 55: 16-20, 1997.
104) Takahashi Y: Survival without tumor shrinkage: re-evaluation of survival gain by cytostatic effect of chemotherapy. JNCI 87: 1262, 1995.
P.1220 掲載の参考文献
1) 垣添忠生: がんの統計. 財団法人がん研究振興財団, 東京, 1997.
3) Berenblum I: The cocarcinogenic action of craton resin. Cancer Res. 1: 44-48, 1941.
4) Cohen SM, Arai M, Jacobs JB, et al: Promoting effect of saccharin and DL-triptophan in urinary bladder carcinogenesis. Cancer Res. 39: 1207-1217, 1979.
5) Tsuji I: Environmental and industrial cancer of the bladder in Japan. Acta Un Int Cancer. 18: 662-666, 1962.
6) 松島正浩, 村上憲彦, 深沢 潔・他: 職業性膀胱癌-スクリーニング開始後15年間における臨床成績とその意義-. 日泌尿会誌 74: 81-99, 1983.
8) 日本泌尿器科学会, 日本病理学会(編) : 膀胱癌取扱い規約. 金原出版, 東京, 1993.
9) UICC: TNM classification of malignant tumours. 4th Ed, 2nd revision (eds. by Hermanek P and Sobin LH) , Springer, Berlin, Heidelberg, New York, 1992.
11) UICC: TNM classification of malignant tumours. (eds. by Sobin LH and Wittekind Ch, Wiley-Liss) , 5th Ed, New York, Chichester, Weiheim, Brisbane, Singapore, Toronto, 1997.
13) Farrow GM, Barlebo H, Enjoji M: Transitional cell carcinoma in situ. Progree in clinical and biological research. In: Developments in Bladder Cancer (eds. by Louis D, Niijima T, Prout G) , Alan R. Liss, New York, 1986, pp. 85-96.
17) Miyanaga N, Akaza H, Kameyama S, et al: Significance of the BTA test in bladder cancer: Amulticenter trial. Int. J. Urol. (in press)
18) 島居 徹, 笠谷俊也, 今田世紀: 人間ドックの経腹的超音波検査で発見された膀胱腫瘍. 日泌尿会誌 83: 1847-1851, 1992.
20) 服部一紀, 樋之津史郎, 島居 徹・他: 内視鏡用細径プローブを用いた膀胱腫瘍の経尿道的超音波診断. 超音波医学 20: 543-547, 1993.
21) Hoshi S: Evaluation of neoadjuvant therapy in locally invasive bladder cancer: Core biopsy of bladder tumors and aspiration biopsy of regional nodes. In: Evaluation of chemotherapy in bladder cancer (eds. by Villavicencio H, Fair WR) , Churchill Livingstone, Edinburgh, 1992, p. 61.
25) Cairns P, Shaw ME, Knowles MA: Initiation of bladder cancer may involve deletion of a tumor suppressor gene on chromosome. Oncogene 8: 1083-1085, 1993.
26) Spruck CH III, Ohneseit PF, Conzalez-Zuluetta M, et al: Two molecular pathways to transitional cell carcinoma of the bladder. Cancer Res. 54: 784-788, 1994.
28) Bringuier PP, Umbas R, Schaafama HE, et al: Decreased E-cadherin immunoreactivity correlates with poor survival in patients with bladder tumors. Cancer Res. 53: 3241-3245, 1993.
29) Shimazui T, Schalken JA, Giroldi LA, et al: Prognostic value of cadherin-associated molecules (α-, β-, andγ-catenins and p 120 cas) in bladder tumors. Cancer Res. 56: 4154-4158, 1996.
31) Liotta LA: Tumor invasion and metastasis-Role of the extracellular matrix: Rhoads memorial award lecture. Cancer Res. 46: 1-7, 1986.
32) Vet JAM, Witjes JA, Salvatore AE, et al: Predictive value of p 53 mutations analyzed in bladder washings for progression of high risk superficial bladder cancer. Clin. Cancer Res. (in press)
33) 香川 征: 泌尿器科腫瘍学における分子生物学. 日泌尿会誌 86: 963-978, 1995.
34) 赤座英之: 膀胱腫瘍. 日医誌 111: 365-367, 1994.
50) 鳶巣賢一: 自然排尿型尿路変向術. アトラス尿路変向術(垣添忠生, 岡田裕作編) , 南江堂, 東京, 1993, p. 109.
51) Studer U, Ackermann D, Casanova GA, et al: Anewer form of bladder substitute based on historical perspectives. Semin. Urol. 6: 57-65, 1988.
68) 宮永直人, 大谷幹伸, 赤座英之・他: 浸潤性膀胱癌に対する下腎動注と放射線照射の併用. 日泌尿会誌 82: 1583- 1587, 1991.
69) 宮永直人, 赤座英之: 局所浸潤癌における膀胱温存をめざした集学的治療. 癌の臨床 42: 1309-1314, 1996.
70) Pocock RJ, Ponder BAJ, 0’Sullivan Jp, et al: Prognostic factors in non-infiltrating carcinoma of the bladder: a preliminary report. Br. J. Urol. 54: 711-715, 1982.
74) 日本泌尿器科学会, 日本病理学会(編) : 腎孟・尿管癌取扱い規約. 金原出版, 東京, 1990.
75) Bagley, DH: Endoureteral diagnosis and treatment. Jpn. J. Endourol. ESWL 9: 20-25, 1996.
77) Harada M: Ureteroscopic treatment of transitional cell carcinoma and fibroepithelial polyp of the upper urinary tract. JPn. J. Endourol. ESWL 9: 43-46, 1996.
82) Zeidman EJ, Desmond P, Thompson I: Surgical treatment of carcinoma of the male urethra. Urol. Clin. North Am. 19: 359-372, 1992.
83) Narayan P, Konety B: Surgical treatment of female urethral carcinoma. Urol. Clin. North Am. 19: 373-382, 1992.
P.1244 掲載の参考文献
1) 厚生省大臣官房統計情報部編: 表5. 24悪性新生物の主要部位別にみた性・年次別死亡数及び率(pp. 276-277) , 第1表-1死亡数, 性・年齢(5歳階級) ・死因(三桁基本分類) 別(p. 100) . 平成6年人口動態統計上巻, (財) 厚生統計協会, 1996.
2) 日本病理学会編: 日本病理剖検輯報. 19-34輯, 日本病理剖検輯報刊行会, 1976-1992.
3) 富永祐民, 青木國雄, 花井 彩・他: がん・統計白書-罹患/死亡/予後-1993. 篠原出版, 東京, 1993.
4) Shiraishi T, Watanabe M, Matsuura H, et al: The Frequency of latent prostatic carcinoma in young males: the Japanese experience. In Vivo 8: 445-447, 1994.
6) 藤田知洋, 蟹本雄右, 秋野裕信・他: 前立腺偶発癌に関する研究. 泌尿器科紀要 37: 695-703, 1991.
11) 原田昌興, 根本良介, 内田克紀・他: 日米前立腺癌の病理組織学的比較. 日泌尿会誌 84: 1110-1118, 1993.
12) Parkin DM, Muir CS, Whelan SL, et al: Cancer Incidence in Five Countries, Vol. VI, No. 120, IARC Scientific Publications, Lyon, 1992.
14) Pour PM, Groot K, Kazakoff K, et al: Effects of high-fat diet on the patterns of prostatic cancer induced in rats by N-nitrosobis(2-oxopropyl) amine and testosterone. Cancer Res. 51: 4757-4761, 1991.
16) Andersson SO, Baron J, Wolk A, et al: Early life risk factors for prostate cancer: apopulation-based case control study in Sweden. Cancer Epidemiol. Biomarkers Prev. 4: 187-192, 1995.
19) 吉田 修, 大石賢二, 岡田謙一郎・他: 日本人: 前立腺癌の疫学的研究. 前立腺癌の基礎と臨床(前立腺研究財団編) . 金原出版, 東京, 1988, pp. 61-77.
28) 日本泌尿器科学会・日本病理学会編: 前立腺癌取扱い規約(第2版) . 金原出版, 東京, 1992.
29) Gleason DF, VACURG: Histologic grading and clinical staging of prostatic carcinoma. In Urologic Pathology: The prostate(ed by Tannenbaum M) , Lea and Febiger, Philadelphia, 1977, pp. 171-198.
36) di Sant’Agnese PA: Neuroendocrine differentiation in carcinoma of the prostate. Diagnostic, prognostic and therapeutic implications. Cancer (supPl.) 70: 254-268, 1992.
38) TNM Classification of Malignant Tumours. 5th. ed, edited by Sobin LH and Wittekind Ch, 1997.
43) Bogdanowicz JF, Bentvelsen FM, Oosterom R, et al: Evaluation of prostate-specific antigen and prostatic acid phosphatase in untreated prostatic carcinoma and benign prostatic hyperplasia. Scand. J. Urol Nephrol. 138 (Suppl.) : 97-103, 1991.
45) Lowe FC, Trauzzi SJ: Prostatic acid phosphatase in 1993. Its limited clinical utility. Urol. Clin. North Am. 20: 46) 589-595, 1993.
50) Wang MC, Valenzuela LA, Murphy GP, et al: Purification of a human prostate specific antigen. Invest. Urol. 17: 159-163, 1979.
51) Hara M, Inoue T, Koyanagi Y, et al: Immunoelectrophoretic studies of the protein component in human seminal plasma(especially its specific component) . (Forensic immunological study of body fluid and secretions. VI) Jpn. J Legal Med. 23: 117-122, 1969.
53) Kuriyama M, Akimoto S, Akaza H, et al: Comparison of various assay systems for prostate-specific antigen. Jpn. J. Clin. Oncol. 22: 393-399, 1992.
55) Small EJ: Prostate cancer: who to screen, and what the results mean. Geriatrics 48: 28-30, 35-38, 1993.
60) Yamamoto M, Hibi H, Miyake K: Prostate-specific antigen levels in acute and chronic bacterial prostatitis. Acta. Urol. Jpn. (泌尿器科紀要) 39: 445-449, 1993.
86) Sutton MA, Gibbons RP, Correa RJ Jr: Is deleting the digital rectal examination a good idea?. West. J. Med. 155: 43-46, 1991.
91) 今井強一, 山中英寿: Screening examination for prostate cancer. Early detection and mass screening. 日泌尿会誌 84(7) : 1175-1187, 1993.
97) 渡辺 泱: 経直腸的超音波断層法の開発と応用. 日泌尿会誌 65: 613-632, 1974.
112) 冨田京一, 鳶巣賢一, 庭川 要・他: 前立腺癌根治症例におけるリンパ節転移と予後. 日泌尿会誌 86(8) : 1322- 1327, 1995.
119) Huggins C, Hodges CV: Studies on Prostate Cancer. 1. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res. 1: 293-297, 1941.
123) Kadohama M, Kirdani RY, Madajewicz S, et al: Estramustine. Metabolic pattern and possible mechanisms for its action in prostate cancer. N. Y. State J. Med. 79: 1005-1009, 1979.
135) 斉藤 泰: 2. 内分泌療法 b) 去勢術・エストロゲン剤・アンチアンドロゲン剤療法(内分泌療法の効果と限界) . 前立腺癌診療マニュアル(前立腺研究財団編) , 金原出版, 東京, 1995, pp. 334-349.
136) Walsh PC: Radical retropubic prostatectomy. In: Campbell’s Urology 6 th ed. (ed by Walsh PC, et al) , Saunders, Philadelphia, pp. 2865-2886.
137) Paulson DF: Perineal prostatectomy. In: Campbell 's Urology 6 th ed. (ed by Walsh PC. et al) , Saunders, Philadelphi. a, 1992, pp. 2887-2899.
138) Carlin BI, Resnick MI: Anatomic approach to radical perineal prostatectomy. Urol. Clin. North Am. 22: 461-473, 1995.
160) Isaka S, Shimazaki J, Akimoto S, et al: A prospective randomized trial for treating stages B 2 and C prostate cancer: radical surgery or irradiation with neoadjuvant endocrine therapy. Jpn. J. Clin. Oncol. 24: 218-223, 1994.
161) Maeda O, Meguro N, Saiki S, et al: Preoperative endocrine therapy in patients with locally advanced prostate cancer. Jpn. J. Clin. Oncol. 25: 135-139, 1995.
219) Straus MJ, Fleit Jp, Engelking C: Treatment of advanced prostate cancer with cyclophosphamide, doxorubicin, and methotrexate. Cancer Treat. Rep. 66: 1797-1802, 1982.
228) Servadio C, Mukamel E, Nussbaum B: Fifteen years’experience of combined hormone/chemotherapy in metastatic prostate cancer Urology 39: 274-276, 1992.
232) Austenfeld MS: Treatment of stage A l prostate cancer: the case for observation. Semin. Urol. 11: 58-63, 1993.
253) Adolfsson J: Radical prostatectomy, radiotherapy or deferred treatment for localized prostate cancer?. Cancer Surv. 23: 141-148, 1995.
256) Byer DP: The Veterans Administration Cooperative Urological Reserch Group’s study of Cancer of the prostate. Cancer 32: 1126-1130, 1973.
259) Bagshaw MA: Radiotherapeutic treatment of prostatic carcinoma with pelvic node involvement, Urol. Clin. North Am. 11: 297-304, 1984.
273) Labrie F, Dupont A, Cusan L, et al: Major advantages of"early"administration of endocrine combination therapy in advanced prostate cancer. Clin. Invest. Med. 16: 493-498, 1993.
275) Cassileth BR, Solowy MS, Vogelzang NJ, et al: Patients’choice of treatment in stage D prostate cancer. Urology 33(5 Suppl) : 57-62, 1989.
280) World Health Organization: Cancer pain relief and palliative care. Technical Report Series No. 804, WHO, Geneva, 1990.
P.1264 掲載の参考文献
1) Forman D, Moller H: Testicular cancer. Cancer Surv. 19: 323-341, 1994.
2) Hawkins C, Miaskowski C: Testicular cancer: a review. Oncol. Nurs. Forum 23(8) : 1203-1211, 1996.
5) 日本泌尿器科学会・病理学会編: 精巣腫瘍取扱い規約. 第2版, 金原出版, 東京, 1997, pp. 65-75.
8) Richie JP: Testicular cancer: What staging investigations are indicated?Semin. Urol. Oncol. 14: 13-16, 1996.
12) Sobin LH, Wittekind CH: TNM classification of malignant tumors. 5th ed, Wiley-Liss, New York, 1977, pp. 174- 177.
13) Moul JW, Heidenreich A: Prognostic factors in low-stage nonseminomatous testicular cancer. Oncology 10: 1359-1374, 1996.
16) Bosl GJ, Geller NL, Cirrincione C, et al: Multivariate analysis of prognostic variables in patients with metastatic testicular cancer. Cancer Res. 43: 3403-3407, 1983.
20) Stoter G, Denis L: The chemotherapy of disseminated testicular non-seminomatous germ cell tumors and the clinical research of the EORTC genitourinary group. Acta Uro1. Belg. 53: 428-435, 1985.
31) Einhorn LH: Salvage therapy for germ cell tumors. Semin. Oncol. 21(suppl. 7) : 47-51, 1994.
P.1278 掲載の参考文献
1) 厚生省大臣官房統計情報部編: 平成7年人口動態統計. (財) 厚生総計協会, 1997, p. 274.
2) 滝 一郎: 子宮癌登録委員会報告: 昭和56年度子宮頸癌患者年報. 日産婦誌 29: 1779-1791, 1977.
3) 工藤隆一: 婦人科腫瘍委員会報告: 1993年度子宮頸癌患者年報. 日産婦誌 49: 41-75, 1997.
5) Rotkin ID: Adolescent coitus and cervical cancer associations of related events with incerased risk. Cancer Res. 27: 603-617, 1967.
6) Keighley E. Carcinoma of the cervix among prostitutes in a women’s prison. Bt. J. Verner. Dis. 44: 245-255, 1968.
14) Barron BA, Richart RM: Statistical model of the natural history of cervical carcinoma. II. Estimates of the transition time from dysplasia to carcinoma in situ. J. Natl. Cancer Inst. 45: 1025-1030, 1970.
15) Kashigarian M, Dunn JE: The duration of intraepithelial and preclinical squamous cell carcinoma of the uterine cervix. Am. J. Epidemiol. 921221-222, 1970.
18) Clemmesen J, Poulsen H: Report of the Ministry of the Interior Document 3. Copenhagen, 1971.
19) 日本産科婦人科学会, 日本病理学会, 日本医学放射線学会編: 子宮頸癌取扱い規約. 金原出版, 東京, 1997.
27) Gallup DG, Harper RH, Stock RJ: Poor prognosis in patients with adenosquamous cell carcinoma of the cervix. Obstet. Gynecol. 65: 416-422, 1985.
28) Yazigi R, Sandstad J, Munoz AK, et al: Adenosquamous carcinoma of the cervix: Prognosis in stage IB. Obstet. Gynecol. 75(6) : 1012-1015, 1990.
32) Strang P, Eklund G, Stendahl B, et al: S-phase rate as a predictor of early recurrences in carcinoma of the uterine cervix. Anticancer Res. 7: 807-810, 1987.
33) Kolstad P, Klelm V: Long term follow up of 1121 cases of carcinoma-in situ. Obstet. Gynecol. 48: 125-129, 1976.
34) Creasman WT, Rutledge FN: Carcinoma in situ of the cervix. Obstet. Gynecol. 3: 373-380, 1972.
41) Perez CA: Carcinoma of the uterine cervix. In: Principles and Practice of Radiation Oncology(eds. by Perez CA, Brady LW) , 2nd Ed, JB Lippincott, Philadelphia, 1992, pp. 919-965.
42) Perez CA, Kurman RJ, Stehman FB, et al: Uterine Cervix. Ch 271n: Principles and Practice of Clinical Gynecologic Oncology(eds. by Hoskins WJ, Perez CA, Young RC) , 2nd Ed, JB Lippincott, Philadelphia, 1992, pp. 591-662.
44) Homesley HD, Raben M, Blake DD, et al: Relationship of lesion size to survival in patients with stage IB squamous cell carcinoma of the cervix uteri treated by radiation therapy. Surg. Gynecol. Oncol. 150: 529-531, 1980.
49) Piver MS, Chung WS: Prognostic significance of cervical lesion size and pelvic node metastasis in cervicalcarcinoma. Obstet. Gynecol. 46: 507-542, 1975.
51) Mendenhall WM, McCarty PJ, Morgan LS, et al: Stage IB or IIA-B carcinoma of the intact uterine cervix≧ 6cm in diameter: Is adjuvant extrafacial hysterectomy beneficial? lnt. J. Radiat. Oncol. Biol. Phys. 21: 899-904, 1991.
52) Alberts DS, Garcia D, Mason-Liddil N: Cisplatin in advanced cancer of the cervix: An update. Semin. Oncol. 18: 11-24, 1991.
54) Wallace H, Hreshchshyn M, Wilbanks G, et al: Comparison of the therapeutic effect of adriamycin alone versus adriamycin plus vincristine versus adriamycin plus cyclophosphamide in the treatment of advanced carcinoma of the cervix. Cancer Treat. Rep. 62: 1435-1441, 1978.
57) 竹内正七, 土橋一慶, 藤本征一郎・他: 子宮頚癌および卵巣癌に対するCPT-11の後期第2相試験. CPT-11研究会婦人科癌分科会. 癌と化学療法 18: 1681-1689, 1991.
58) Wasserman T, Carter S: The integration of chemotherapy into combined modality treatment of solid tumors: V田. Cervical cancer. Cancer Treat. Rev. 4: 25-46, 1977.
63) Kirsten F, Atkinson KH, Coppleson JVM, et al: Combination chemotherapy followed by surgery or radiotherapy in patients with locally advanced cervical cancer. Br. J. Obstet. Gynecol. 941583-588, 1987.
68) Rabinovich MG, Focaccia G, Ferreyra R, et al: Neoadjuvant chemotherapy for cervical carcinoma. Obstet. Gynecol. 78: 685-688, 1991.
81) 平林光司: 子宮頸癌neoadjuvant chemotherapy. "図説産婦人科VIEW腫瘍薬物療法"メジカルビュー社, 東京, 1994, p. 4209.
82) 工藤隆一: 婦人科腫瘍委員会第34回治療年報. 日産婦誌 49: 273-306, 1997.
P.1290 掲載の参考文献
1) Hacker NF, Fifel P, McGuire W, et al: Vulva. In: Principles and Practice of Gynecologic Oncology(eds by Hoskins WJ, Perez CA, Young RC) , JB Lippincott, Philadelphia, 1992, pp. 537-566.
2) 杉森 甫, 工藤隆一(婦人科腫瘍委員会) : 本邦における外陰癌の臨床統計調査報告. 日産婦会誌 47: 685-693, 1992.
4) Kaufman RH, Friearich EG Jr, Gardner HL: Benigndiseases of the vulva and vagina. 3rd Ed, Year-Book Medical Publishers, Chicago, 1989.
6) Synopsis of Gynecologic Oncology(eds by Morrow Cp, Curtin JP, Townsend DE) , 4th Ed, Churchill Livingstone, New York, 1993.
8) DiSaia PJ, Creasman WT: Clinical Gynecologic Oncology, 4th Ed, Mosby-Year Book, St Louis, 1993.
11) Plentl AA, Friedman EA: Clinical significance of vulvar lymphatics. In: Lymphatic System of the Female Genitalia, W. B. Saunders, Philadelphia, 1971, pp. 28-29.
12) Stehman FB, Burdy BN, Dvoretsky PM, et al: Early stage I carcinoma of the vulva treated with ipsilateral superficial inguinal lymphadenectomy and modified radical hemivulvectomy. A prospective study of the Gynecologic Oncology Group. Obstet. Gynecol. 79: 490-497, 1992.
14) Homesley HD, Bundy BN, Sedlis A, et al: Radiation therapy versus pelvic node resection for carcinoma of the vulva with positive groin nodes. Obstet. Gynecol. 68: 733-740, 1986.
19) Baggish MS, Dorsey JH: CO21aser for the treatment of vulvar carcinoma in situ. Obstet. Gynecol. 57: 371-375, 1981.
22) Hacker NF, Berek JS, Lagasse LD, et al: Individualization of treatment for stage I squamous cell vulvar carcinoma. Obstet. Gynecol. 63: 155-162, 1984.
26) 須川 佶, 橋本正淑, 鈴木雅州・他: 本邦における外陰癌の発症ならびに治療の現況. 日産婦会誌 32: 177-186, 1980.
27) Trope C, Johnsson JE, Larsson G, et al: Bleomycin alone or combined with mitomycin C in treatment of advanced or recurrent squamous cell carcinoma of the vulva. Cancer Treat. Rep. 64: 639, 1980.
28) 清水敬生, 荷見勝彦, 八木裕昭・他: FIGO IV期の外陰癌に対するBOMP療法. 日産婦会誌 41: 609-612, 1989.
29) Deppe G, Bruckner H and Cohen C: Adriamycin treatment of advanced vulvar carcinoma. Obstet. Gynecol. 50: 138, 1977.
P.1304 掲載の参考文献
3) Koss LG, Schreiber K, Oberlander SG, et al: Detection of endometrial cancer and hyperplasia in a symptomatic women. Obstet. Gynecol. 64: 1-11, 1984.
4) Robboy SJ, Bradley R: Changing trends and prognostic features in endometrial cancer associated with exogenous estrogen therapy. Obstet. Gynecol. 54: 269-277, 1979.
7) Morrow CP, Curtin Jp, Townsend DE et al: Synopsis of Gynecologic Oncology(eds by Morrrow CP, Curtin Jp, Townsend DE) , 4th ED. Churchill Livingstone, New York, 1993.
8) Hartz A, Fisheer M, Cassell E, et al: Obesity and endometrial cancer. Intern. Med. 6: 61-65, 1985.
9) Sperofff L, Glass RH, Kase NG: Clinical gynecologic endocrinology and infertility, 4th Ed. Williams and Wilkins, Baltimore, 1989.
10) Brakat RR, Park RC, Grigsby PW, et al: Corpus: Epithelial Tumors. In: Principles and Practice of Gynecologic Oncology(eds by Hoskins WJ, Perez CA, Young RC) , JB Lippincott, Philadelphia, 1997, pp. 359-896.
15) Jordan JC, Assikis VJ: Endometrial carcinoma and Tamoxifen: Clearing up a controversy. Clin. Cancer Res. 1: 467-472, 1995.
16) Ovarian Malignancies, Diagnostic and Therapeutic Advances(ed by Piver MD) , Churchill Livingstone, New York, 1987.
17) Hacker NF: Uterine Cancer. In Practical Gynecologic Oncology. 1996, pp. 285-326.
18) 婦人科腫瘍委員会第32回治療年報. 日産婦会誌 46: 935-1001, 1994.
19) 婦人科腫瘍委員会第34回治療年報. 日産婦会誌 49: 273-306, 1997.
20) 婦人科腫瘍委員会報告. 日産婦会誌 47: 177-211, 1995.
21) 婦人科腫瘍委員会報告. 日産婦会誌 49: 41-75, 1997.
22) DuBeshter B, Angel C, Lin J, et al: Gynecologic Tumors. In: Clinical Oncology, A Multidiciplinary Approach for Physicians and Students(ed by Rub in P) , 7th Ed. WB Saunders, Philadelphia, 1994, Chapter 22.
24) Gal D : Horomonal therapy for lesions of the endometrium. Semin. Oncol . 13: 33-36, 1986.
26) Hawwa ZM, Nahhas WA, Copenhauer EH: Postmenopausal bleeding. Lahey Clin. Foundation Bull. 19: 61, 1970.
27) Pacheco JC, Kempers RD: Etiology of postmenopausal bleeding. Obstet. Gynecol. 32: 40-46, 1968.
32) 松浦佑介, 柏村正道, 篠原道興・他: 子宮体癌筋層浸潤の評価におけるMRIの有用性について. 日産婦会誌 44: 787-792, 1992.
34) Powell MC, Wowmack C, Buckley J, et al: Preoperative magnetic resonance imaging of stage I endometrial adenocarcinoma. Br. J. Obstet. Gynecol. 93: 353-360, 1986.
39) 日本産科婦人科学会, 日本病理学会, 日本医学放射線学会: 子宮体癌取扱い規約, 金原出版, 東京, 1987.
40) Boronow RC, Morrow CP, Creaseman WT, et al: Surgical staging in endometrial cancer: Clinical-pathologic findings of a prospective study. Obstet. Gynecol. 63: 825-832, 1984,
42) FIGO: Classification and staging of malignant tumors in the female pelvis. Int. J. Gynaecol. Obstet. 9: 172, 1971.
43) 西谷雅史, 櫻木範明, 田中俊誠・他: 子宮体癌のFIGO新進行期分類(1989) についての検討-旧進行期分類(1983) との比較ならびに予後因子の解析. 日産婦会誌 43: 451-457, 1991.
44) FIGO: Annual Report on the Results of Treatment in Gynecological Cancer. Vol 21. Int. J. Gynecol. Obstet. 36 (Suppl.) : 1, 1991.
47) Sutton GP: The significance of positive peritoneal cytology in endometrial cancer. Oncology 4: 21, 1990.
48) Wharton JT, Mikura JJ, Mettlin C, et al: Risk factors and current management in carcinoma of the endometrium. Surg. Gynecol. Obstet. 162: 515-520, 1986.
50) 竹島信宏, 梅沢 聡, 山脇孝晴・他: 子宮体癌筋層浸潤欠如症例に対する研究. 日産婦会誌 46: 553-558, 1995.
53) 西谷雅史, 櫻木範明, 田中俊誠・他: 子宮体癌の組織学的予後判定因子についての検討. 日産婦会誌 44: 453-460, 1992.
56) Lurain JR, Rumsey NK, Schink JC, et al: Prognostic significance of positive peritoneal cytology in clinical stage Iadenocarcinoma of the endometrium. Obstet. Gynecol. 74: 175-179, 1989.
58) Turner DA, Gershenson DM, Arkinson N, et al: The prognostic significance of peritoneal cytology for stage I endometrial cancer. Obstet. Gynecol. 74: 775-780, 1989.
63) Stendahl U, Wagenuiis G, Strang P, et al: Flow cytometry in invasive endometrial carcinoma. In Vivo 2: 123- 127, 1988.
64) 塚本直樹: 婦人科癌に対する腹部大動脈周囲リンパ節廓清の適応と手技. 研修コーナー. 日産婦会誌 46: N103- N106, 1995.
67) Larsen DM, Copeland LJ, Gallager HS, et al: The significance of residual tumor after preoperative pelvic irradiation for stage II endometrial carcinoma. Obstet. Gynecol. 70: 916-919, 1987.
72) Marchetti DL, Piver MS, Tsukada Y, et al: Prevention of vaginal recurrence of stage I endometrial adenocarcinoma with postoperative vaginal radiation. Obstet. Gynecol. 67: 399-402, 1986.
79) MacDonald RR, Thorogood J, Mason MK: Arandomized trial of progestogens in the primary treatment of endometrial carcinoma. Br. J Obstet Gynecol. 95: 166-174, 1988.
82) Swenerton KD: Treatment of advanced endometrial adenocarcinoma with tamoxifen. Cancer Treat. Rep. 64: 805-811, 1981.
84) Ball H, Blessing JA, Lentz S, et al: A Phase II trial of Taxol in advanced and recurrent adenocarcinoma of the endometrium. A Gynecologic Oncology Group study. Proceedings of the Society of Gynecologic Oncologists Annual Meeting. (Abstr#69) 1995, p. 102.
86) Turbow MM, Thobon J, Ballon S, et al: Chemotherapy of advanced carcinoma with platinum, adriamycin, and cyclophosphamide. Proc. Am. Assoc. Cancer Res. 1: 108-112, 1982.
87) Creasman WT, Henderson D, Hinshq W, et al: Estrogen replacement therapy in the patient treated for endometrial cancer. Obstet. Gynecol. 46: 326-330, 1986.
P.1339 掲載の参考文献
1) がん統計白書-罹患/死亡/予後-1993. 富永祐民, 青木国雄, 花井 彩, 栗原 登 (編) , 篠原出版, 東京, 1993.
2) Greene MH, Clark JW, Blaynney DW: The epidermiology of ovarian cancer. Semin. Oncol. 11(3) : 209-226, 1984.
4) Gross Jp, Schlesselman JJ: The estimated effect of oral contraceptive use on the cumulative risk of epithelial ovarian cancer. Obstet. Gynecol. 83: 419-424, 1992.
9) Easton DF, Ford D, Bishop DT, and the Breast Cancer Linkage Consortium: Breast and ovarian cancer incidence in BRCA 1-mutation carriers. Am. J. Hum. Genet. 56: 265-271, 1995.
13) Bell D, Flott T, Pastel-Levy C, et al: DNA ploidy of ovarian serous borderline tumors (SBT) and their extraovarian implants. [Abstr. ] Mod. Pathol. 2: 8a, 1989.
16) Heaps JM, Neiberg RK, Gerek JS: Malignant neoplasms arising in endometriosis. Obstet. Gynecol. 85: 1023-1028, 1990.
29) Reed E, Ostchega Y, Steinberg SM, et al: Evaluation of platinum-DNA adduct levels relative to known prognostic vaiables in a cohort of ovarian cancer patients. Cancer Res. 50: 2256-2260, 1990.
31) Griffiths CT: Surgical resection of tumor bulk in the primary treatment of ovarian carcinoma. Natl. Cancer Inst. Monogr. 42: 101-104, 1975.
32) Hacker NF, Berek JS, Lagasse LD, et al: Primary cytoreductive surgery for epithelial ovarian cancer. Obstet. Gynecol. 61: 413-420, 1983.
36) Luesley D, Finn C, Varma R: The role of surgery in epithelial ovarian cancer. In: Ovarian Cancer 2, Biology, diagnosis and management (eds by Sharp F, Mason WP, Creasman W) . Chapman & Hall Medical, London, pp. 357-366.
40) McGuire WP, Hoskins WJ, Brady MF, et al: A phase III trial of dose intense versus standard dose cisplatin and cytoxan in advanced ovarian cancer. Proc. ASCO 11: 226, 1992.
41) Kaye SB: High dose cisplatin (100 mg/sm) is more effective than low dose (50 mg/sm) in combination with cyclophosphamide (750 mg/sm) for the treatment of advanced ovarian cancer. Proc. Int. Gynecol. Cancer Soc. 3: 170, 1991.
43) Ozols RF, Rubin SC, Dembo AJ, et al: Epithelial Ovarian Cancer. In: Principles and Practice of Gynecologic Oncology. JB. Lippincott, Philadelphia, 1992, pp. 731-781.
46) McGuire WP, Hoskons WJ, Brady MF, et al: Taxol and cisplatin (TP) improves outcome in advanced ovarian cancer as compared to cytoxan and cisplatin. Gynecologic Oncology Group. Proc. Am. Soc. Clin. Oncol. 14: 274 (771) , 1995.
48) JP Neijt, M Hanse, SW Hansen, et al: Randomized phase III study in previously untreated epithelial ovarian cancer FIGO stage II B, IIC, III, IV, comparing paclitaxel-cisplatin and paclitaxel carboplatin. ASCO 1259, 1997.
49) McGuire WP: Ovarian Cancer. In: Paclitaxel in Cancer Treatment. Marcel Dekker, New York, 1995, pp. 201-221.
51) Raptis G, Tiersten A, Fennelly D, et al: The addition of paclitaxel to high dose cyclophosphamide+filgrastim (G-CSF) markedly enhances the mobilization of CD 34+ peripheral blood progenitor cell (PBPC) in patients with responding metastatic breast cancer undergoing high dose chemotherapy. Proc. Am. Soc. Clin. Oncol. 14: 313 (919) , 1995.
52) Omura GA, Brady MF, Delmore JE, et al: A randomized trial of paclitaxel at 2 dose levels and filgrastim (GCSF) at 2 doses in platinum pretreated epithelial ovarian cancer: A Gynecologic Oncology Group, SWOG, NCCTG and ECOG study. Proc. Am. Soc. Clin. Oncol. 15: 280(755) , 1996.
56) Piccart MJ, Speyer JL, Markman M, et al: Intraperitoneal chemotherapy: technical experience at five institutions. Semin. Oncol. 12(3) : 90-96, 1985.
58) Alberts DS, Liu PY, Hannigan EV, et al: Phase III study of intraperitoneal cisplatin/intravenous cyclophosphamide vs IV CDDP/IV CPA in patients with optimal disease stage III ovarian cancer. A SWOG-GOG-ECOG intergroup study (INT OO51) . Proc. Am. Soc. Clin. Oncol. 14: 272(760) , 1995.
61) Markman M: personal communication.
63) Hatae M, Onishi Y, Maeda Y: Current status of treatment for ovarian carcinoma in Japan. Cancer Chemotherapy. Challenges for the Future 10: 215-225, 1995.
64) Vermorken JB, Kobierska A, Chevallier B, et al: Phase II study of high-dose epirubicin (HDE) in ovarian cancer patients previously treated with cisplatin. Proc. Am. Soc. Clin. Oncol. 14: 274, 1995.
67) Burris H, Fields S: Clinical update on the topoisomerase 1 inhibitor. 31 st Annual Meeting, Am. Soc. Clin. Oncol. Educational Book, 1995, pp. 104-111.
69) 山本謙二 , 菊池義公, 平松久和. ・他: タキソール併用投与におけるシスプラチン耐性克服の可能性. 日産婦誌 94臨増号S300, 1997.
70) Shpall EJ, Cagnoni PJ, Purdy M, et al: High-dose chemotherapy with autologous hematopoietic cell support (AHCS) for the treatment of epithelial ovarian cancer. Am. Soc. Clin. Oncol. Educational Book, 1995, pp. 360-364
71) Peter WP: The value of high-dose therapy in breast cancer. 12 th Bristol-Myers Squibb Nagoya International Cancer Treatment Symposium “New therapeutic strategies for higher cure rates. High-dose therapy and new therapeutic modality. ” pp. 36-37 (Abstr.) .
72) Scully RE: Tumors of the Ovary and Maldeveloped Gonads. Fascicle 16. Whashington, DC ' Armed Forces Institute of Pathology, 1979.
73) Kurman RJ, Norris HJ: Germ cell tumors of the ovary. Hum. Pathol. 1: 291-325, 1981.
74) Thomas GM, Dembo AJ, Hacker NF, et al: Current therapy for dysgerminoma of the ovary. Obstet. Gynecol. 70: 268-275, 1087.
76) Newlands ES, Southall pJ, Paradinas FJ, et al: Management of ovarian germ cell tumours. In: Textbook of Uncommon Cancer. (eds by Williams CJ, Kaikorian JG, Green MR, Raghaaran D) John Wiley & Sons, NewYork, 1988, pp. 37-53
78) Berek JS, Hacker NF: Ovarian and fallopian tubes. In: Cancer Treatment, 4th ed (ed. by Haskell CM) , WB Saunders, Phidadelphia, 1995.
80) Slayton RE: Management of germ cell and stromal tumors of the ovary. Semin. Oncol. 11: 299-313, 1984.
81) Serov SF, Scully RE, Robin IH: Histological typing of ovarian tumors. International Histological Classification of Tumors, No. 9. World Health Organization, Geneva, 1973.
91) Loehrer PJ, Elson P, Johnson DH, Williams SD, Trump DL, Einhorn LH. A randomized trial of cisplatin plus etoposide with or without bleomycin in favorable prognosis disseminated germ cell tumors: an ECOG study. Proc. Am. Soc, Clin. OncollO: 540, 1991.
94) Nakashima N, Young RH, Scully RE: Androgenic granulosa-cell tumors of the ovary: a clinicopathologic analysis of 17 cases and review of the literature. Arch. Pathol. Lab. Med. 108: 786-791, 1984.
95) Norris HJ, Taylor HR: Virlization associated with cystic granulosa tumors. Obstet. Gynecol. 34: 629-635, 1969.
99) Evans AT 3 d, Gaffey TA, Malkasisn GD, et al: Clinicopathologic review of 118 granulosa and 82 theca cell tumors. Obstet. Gynecol. 55: 231-238, 1980.
103) Plantaz D, Flamant F, Vassal G, et al: Tumeurs de la ganulosa de l'ovaire chez l'enfant et l'adolescente. Arch. Fr. Pediatr. 49: 793-798, 1992.
106) Fishman A, Kudelka A, Edwards C, et al: GnRH agonist (Depot-Lupron) in the treatment of refractory of persistent ovarian granulosa-cell tumor (GCT) [Abstr. ]. Proc. ASCO 13: 236, 1994.
117) Berkowitz RS, Goldstein DP: Pathogenesis of gestational trophoblastic neoplasmas. Pathobiology. Annual. 11: 391-411, 1981.
120) Berkowitz RS, Goldstein DP, Bernstein MR: Advances in management of partial molar pregnancy. Contemp. Obset. Gynecol. 36: 33-44, 1991.
122) Fine C, Bundy AL, Berkowitz RS, et al: Sonographic diagnosis of partial hydatidiform mole. Obstet. Gynecol. 73: 414-418, 1989.
123) Berkowitz RS, Goldstein DP, DuBeshter B, et al: Management of complete molar pregnancy. J. Reprod. Med. 32: 634-639, 1987.
125) Genest DR, LaBorde O, Berkowitz RS, et al: A clinicopathologic study of 153 cases of complete hydatidiform mole (1980-990) : histologic garde lacks prognostic significance. Obstet. Gynecol. 78: 402-409, 1991.
126) Berkowitz RS, Goldstein DP: The management of molar pregnancy and gestational trophoblastic tumors. In: Gynecologic Oncology, 2nd Ed (eds by Knapp RC, Berkowitz RS) , McGraw-Hill, New York, 1993, pp. 328-338.
129) Bakri Y, Berkowitz RS, Goldstein DP, et al: Brain metastases of gestational trophoblastic tumor. J. Reprod. Med. 39: 179-184, 1994.
131) Weed JC Jr, Hammond CB: Cerbral metastatic choriocarcinoma: intensive therapy and prognosis. Obstet. Gynecol. 55: 89-94, 1980.
132) Homesley HD: Development of single-agent chemotherapy regimens for gestational trophoblastic disease. J. Reprod. Med. 39: 185-192, 1994.
134) Curry SL, Blessing JA, DiSaia PJ, et al: A prospective randomized comparison of methotrexate, dactinomycin and chlorambucil versus methotrexate, dactinomycin, cyclophosphamide, doxorubicin, melphalan, hydroxyurea and vincristine in “poor prognosis”metastatic gestational trophoblastic disease: a Gynecologic Oncology Group study. Obstet. Gynecol. 73: 357-362, 1989.
137) Bagshawe KD: Treatment of high-risk choriocarcinoma. J. Reprod. Med. 29: 813-820, 1984.
138) 波多江正紀: 婦人科癌. 妊娠性絨毛疾患. 抗癌剤の選び方, 南江堂, 東京, 1996, pp. 105-109.
P.1368 掲載の参考文献
2) Malawer MM, Link MP, Donaldson SS: Sarcomas of Bone. In: Cancer: Principles and Practice of Oncology (ed by De Vita VT Jr, Hellman S, Rosenberg SA) . 5th ed, JB Lippincott, Philadelphia, 1997, pp. 1789-1852.
3) 日本整形外科学会骨, 軟部腫瘍委員会編: 全国骨腫瘍患者登録一覧表(平成7年度) . 国立がんセンター, 東京, 1996, pp. 23-45.
5) Brennan MF, Casper ES, Harrison: Soft tissue sarcoma. In: Cancer: Principles and Practice of Oncology (ed by De Vita VT Jr, Hellman S, Rosenberg SA) . 5th ed, JB Lippincott, Philadelphia, 1997, pp. 1738-1788.
6) Cordon-Cardo C: Chapter 38. Sarcoma of the soft tissues and bone. Molecular biology of sarcomas. In: Cancer: Principles and Practice of Oncology (ed by DeVita V, Hellman Sm, Rosenberg S) . 5th ed, Lippincott-Raven, Philadelphia, 1997, pp. 1731-1738.
7) 戸口田淳也: 遺伝子解析. 骨腫瘍の診断と治療(平澤泰介編) . OS Now 18, メジカルビュー社, 東京, 1995, pp. 114- 120.
8) Kawaguchi N: Surgical treatment combined preoperative chemotherapy for musculoskeletal sarcoma. In: Cancer chemotherapy challenges for the future (ed by Kimura K, Ota K, Yamada K, Saito H, Ogawa M) . 10, Excerpta Medica, Tokyo, 1995, pp. 248-256.
10) Enneking WF: Asystem for the functional evaluation of the surgical management of musculoskeletal tumors. In: Limb salvage in musculoskeletal oncology (ed by Ennekin WF) . 1987, pp. 5-16.
11) 柴田大法: 外科的治療. Surgical stagingと surgical margin. 骨腫瘍の診断と治療(平澤泰介編) . OS Now 18, メジカルビュー社, 東京, 1995, pp. 158-163.
17) Huvos AG: Bone tumors: diagnosis, treatment and prognosis. 2nd ed, WB Saunders, Philadelphia, 1991, pp. 368-373.
18) Gehan EA, Nesbit ME, Burgert OE, et al: Prognostic factors in children with Ewing 's sarcoma. J. Natl. Cancer Inst. Monogr. 56: 273-278, 1981.
20) Glaubiger D, Makuch R, Wackenhut J, et al: Early results of current combined modality therapy trials in Ewing 's sarcoma at the NCI. In: Jones Samon SE, Adjuvant chemotherapy of Cancer II. Grune and Stratton, New York, 1979, pp. 409-412.
26) Broders A: The microscopic grading of cancer. In: Pack GT et al, Treatment of cancer and apllied diseases. Paul B, Hoeber, London, 1940, pp. 19-41.
29) Beahrs AC, Henson DE, Hutter RV, et al: Mannual for staging of cancer. American Joint Committee on cancer. 4th ed, JB Lippincott, Philadelphia, 1992, pp. 145-149.
30) 日本整形外科学会骨軟部腫瘍委員会編: 整形外科・病理悪性軟部腫瘍取扱い規約. 第2版. 金原出版, 東京, 1989, pp. 59-67.
31) 日本整形外科学会骨軟部腫瘍委員会編: 骨, 軟部肉腫切除縁評価法. 金原出版, 東京, 1989, pp. 31-36.
32) Kotz R, and Salzer M∴Rotation-plasty for childhood osteosarcoma of the distal part of the femur. J, Bone Joint Surg. 64-A: 959-969, 1982.
33) 井上 治. 外科治療. Rotation-plasty (患肢温存的回転形成術) の適応と方法. 骨腫瘍の診断と治療(平澤泰介編) . OS Now 18, メジカルビュー社, 東京, 1995, pp, 203-209.
34) 森 茂樹, 吉川秀樹, 内田淳也・他: 転移性骨盤腫瘍に対する外科的治療. 中部日整災外会誌 38: 199, 1995.
37) 富田勝郎, 砂山千明: 骨肉腫の患肢温存療法. 骨腫瘍の診断と治療(平澤泰介編) . OS Now 18, メジカルビュー社, 東京, 1995, pp. 36-41.
39) Cortes EP, Holland JF, Glidewell O: Amputation and adriamycin in primary osteosarcomas: A 5 year report. Cancer Treat. Rep. 62: 271-277, 1978.
40) Cortes E, Necheles TF, Holland JF, et al: Adriamycin alone vs. adriamycin and high dose methotrexate citrovorum factor rescue as adjuvant to operable primary osteosarcoma: A randomized study by Cancer and Leukemia Group B. Proc. Am. Soc. Clin. Oncol. 20: 412, 1979.
41) Cortes EP, Holland JF, Glidewell O: Osteogenic sarcoma studied by the Cancer and Leukemia Group B. J. Natl. Cancer Inst. Monogr. 5: 207-209, 1981.
45) Sutow WW, Gehan EA, Dyment PG, et al: Multidrug adjuvant chemotherapy for osteosarcoma: Interm report of the Southwest Oncology Group Studies. Cancer Treat. Rep. 62: 265-269, 1978.
46) Rosenberg WF, Ivins JC, Dahlin DC, et al: Effect of adjuvant high-dose methotrexate after amputation. Cancer Treat. Rep. 63: 739-751, 1979.
47) Goorin A, Delorey M, Gelber R, et al: The Dana-Farber Cancer Institute/The children hospital adjuvant chemotherapy trials for osteosarcomas: Three sequential studies. Cancer Treat. Symp. 3: 155-159, 1985.
50) Furuse K, Maeyama I, Yamawaki S, et al: Adjuvant chemotherapy for osteosarcoma with adriamycin, alone versus adriamycin vincristine and high dose methotrexate with citrovorum factor rescue. In Methotrexate in cancer therapy (ed by Kimura K, Wang Y-M) . Raven Press, New York, 1986, pp. 249-255.
55) Pratt CB, Rivera G, Shanks E, et al: Combination chemotherapy for osteosarcoma. Cancer Treat. Rep. 62: 251-257, 1978.
58) Provisor A, Nachman J, Krailo M, et al: Treatment of non-metastatic osteogenic sarcoma (os) of the extremities with pre and post-operative chemotherapy. Proc. Am. Soc. Clin. Oncol. 6: 217, 1987.
59) Kalifa C, Dubousset J, Grandner H, et al: Osteosarcoma (OS) ; An attempt to reproduce T 10 in a single institution. Proc. Am. Soc. Clin. Oncol4: 236, 1985.
66) Jaffe N, Raymond AK, Carrasco H, et al: Effect of escalating courses of intraarterial cis-diamminedichloroplatinum-II (CDDP) on the primary tumor in pediatric osteosarcoma (OS) . Proc. Am. Soc. Clin. Oncol. 6: 217, 1987.
68) Benjamin RS, Chawla SP, Carrasco Ch, et al: Primary chemotherapy of patients with osteosarcoma of an extremity. Proc. Am. Soc. Clin. Oncol. 5: 139, 1986.
71) Weiner MA, Harris MB, Lewis M, et al: Neoadjuvant high-dose methotrexate, cisplatin and doxorubicin for the management of patients with nonmetastatic osteosarcoma. Cancer Treat. Rep. 70: 14.
72) Petrill AS, Gentil FC, Epelman S, et al: Increased survival, limb preservation, and prognostic factors for osteosarcoma. Cancer 681733-737, 1991.
73) Meyer WH, Prat BN, Rao X, et al: Curative therapy for 31-1432, 1986. osteosarcoma without cisplatin-preliminary results of SJCRH OS-91. Proc. Am. Soc. Clin. Oncol. 16: 1844, 1997.
74) Tuchiya H, Tomita K, et al: Intraarterial cisplatin and caffeine with or without doxorubicn for musculoskeletal high-grade spindle cell sarcoma. Oncol. Reports 1: 27-36, 1984.
76) Marti CH, Kroner T, Remagen W, et al: High-dose ifosfamide in advanced osteosarcoma. Cancer Treat. Rep. 69: 115-117, 1985.
96) Huvos AG: Bone tumors; Diagnosis, treatment and prognosis. 2nd ed, WB Saunders, Philadelphia, London, Toronto, 1991, pp. 514-517.
99) Rosenberg SA: Adjuvant chemotherapy of adult patients with soft tissue sarcoma. In: Important Advances in Oncology (ed by DeVita V, Hellman S, Rosenberg S) . Lippincott, Philadelphia, PA, 1985, pp. 273-294.
100) Antman K, Ryan L, Borden E, et al: Pooled results from three randomized adjuvant studies of doxorubicin versus observation in soft tissue sarcoma: 10 year results and review of literature. In Adjuvant Therapy of Cancer VI (ed by Salmon SE) . PA, WB Saunders, Philadelphia, 1990, pp. 529-543.
104) Gherlizoni F, Pignatti G, Fontana M, et al: Soft tissue sarcomas: The experience at the Istituto Ortopedic Rizzoli. Chir. Organi. Mov. 75: 150-154, 1990.
105) Benjamin RS, Terjanian TO, Genoglio CJ, et al: The importance of combination chemotherapy for adjuvant treatment of high risk patients with soft tissue sarcomas of the extremities. In: Adjuvant Therapy of Cancer V (ed by Salmon SE) . Grune & Stratton, New York, 1987, pp. 735-744.
108) Bui NB, Maree D, Coindre JM, et al: First results of a prospective randomized study of CYVADIC adjuvant chemotherapy in adults with operable high risk soft tissue sarcoma. Proc. Am. Soc. Clin. Oncol. 8: 318, 1989.
109) Ravaud A, Buinb, Coindre JM, et al: Adjuvant chemotherapy with CYVADIC in high risk soft tissue sarcoma: A randomized prospe6tive trial. In l Adjuvant Therapy of Cancer VI (Salmon SE) . Grune & Stratton, New York, 1990, pp. 556-566.
117) Bramwell V, Mouridsen HT, Santoro A, et al: Cyclophosphamide vs ifosfamide and mesna: Final report of a randomized phase II trial{n adult soft tissue sarcoma. Eur. J Cancer. Clin. Oncol. 7: 126-131, 1989.
119) Santoro J, Mouridsen HT, Steward W: A randomized EORTC study in advanced soft tissue sarcomas: ADM vs ADM+IFOS vs CYVADIC. Proc. Am. Soc. Clin. Oncol. 9: 309, 1990.
122) Denton JW, Dunham WK, Salter M, et al: Preoperative regional chemotherapy and rapid-fraction irradiation for sarcomas of the soft tissue and bone. Surg. Gynecol. Obstet. 158: 545-551, 1984.
P.1383 掲載の参考文献
1) Balch CM, Houghton AN, Milton GW, et al: Cutaneous Melanoma. 2nd ed. JB Lippincott, Philadelphia, 1992.
2) 斎田俊明: 皮膚悪性黒色腫の診断と治療. Skin Cancer 8 (Special Issue) : 13-37, 1993.
3) 石原和之: 悪性黒色腫, 全国アンケートの集計と説明. Skin Cancer 9 (Special Issue) : 52-68, 1994.
4) UICC (International Union Against Cancer) : TNM classification of malignant tumors. 5th Ed, Wiley-Liss, New York, 1997.
8) 若松一雅: 悪性黒色腫の生物学的指標としてのメラニン関連代謝物の臨床的意義に関する研究. 藤田学園医会誌15(臨時増刊) : 99-139, 1996.
14) 山崎直也: 進行期悪性黒色腫の治療. 日皮会誌 106: 1055-1063, 1996.
16) Lee JE: Melanoma. The M. D. Anderson Surgical Oncology Handbook (eds. by Berger DH, Feig BW, Fuhrman GM) . Little Brown, USA, 1995, pp. 38-60.
17) 斎田俊明, 山本明史: メラノーマ, 診断と治療の手引き. 第96回日本皮膚科学会総会. 学術大会編, 1997, pp. 1-12.
21) 福富隆志: 非定型乳房切除術 (Patey法) . 癌の外科-手術手技シリーズ2乳癌(福富隆志編) , メジカルビュー社, 東京, 1992, pp. 32-45.
22) 七沢 武: 非定型乳房切除術 (両胸筋温存乳房切除術) . 癌の外科-手術手技シリーズ2乳癌(福富隆志編) , メジカルビュー社, 東京, 1992, pp. 46-57.
23) 浅村尚生: 皮膚腫瘍 (特に melanoma) , 頭頸部腫瘍の肺転移の病態と治療. 第33回日本癌治療学会JSCT EDUCA- TIONAL BOOK, 1995, pp. 497-502.
25) Karakousis CP, Velez A, Driscoll DL, et al: Metastasectomy in malignant melanoma. Surgery 115: 295-302, 1994.
30) Mufioz JE, Vifiolas N, Castro J, et al: Metastasis cerebrales de melanoma: estudio de 48 pacientes. Med. Clin. (Barc) 101: 684-687, 1993.
31) Oredsson S, Ingvar C, Str6mblad LG, et al: Palliative surgery for brain metastases of malignant melanoma. Eur. J. Surg. Oncol. 161451-456, 1990.
32) Comis RL: DTIC (NSC-45388) in malignant melanoma: A perspective. Cancer Treat. Rep. 60: 165-176, 1976.
33) DTIC研究グループ(世話人 池田重雄, 石原和之) : 悪性黒色腫に対するdacarbazine (DTIC) の臨床的研究. 臨床皮膚科 36: 183-188, 1982.
35) 石原和之, 池川修一: 悪性黒色腫の診断と治療. 癌と化学療法 12: 1727-1734, 1985.
36) 山崎直也, 佐々木英也, 浅野一弘・他: 進行期悪性黒色腫に対するcisplatin-dacarbazine-vindesine併用化学療法 -21例の投与経験-. 日皮会誌 105: 1439-1444, 1995.
37) Del Prete SA, Maurer LH, 0 'Donnell J, et al: Combination chemotherapy with cisplatin, carmustine, dacarbazine, and tamoxifen in metastatic melanoma. Cancer Treat. Rep. 68: 1403-1405, 1984.
38) McClay EF, Mastrangelo MJ, Bellet RE, et al: Combination chemotherapy and hormonal therapy in the treatment of malignant melanoma. Cancer Treat. Rep. 71: 465-469, 1987.
40) 山崎直也: CDV療法とDAC-Tam療法. 日皮会誌 107: 1661-1663, 1997.
45) Yamamoto A, Ishihara K: Clinical study of DAV+IFN-B therapy (combination adjuvant therapy with intravenous DTIC, ACNU and VCR, and local injection of IFN-B) for malignant melanoma. Int. J. Immunotherapy 12: 73-78, 1996.
46) 石原和之: Human fibroblast interferon (Hu IFN-β) による皮膚悪性腫瘍に対する臨床的研究. 日癌治療会誌 18: 41-53, 1983.
50) Legha SS, Ring S, Bedikian A, et al: Treatment of metastatic melanoma with combined chemotherapy containing cisplatin, vinblastine and dacarbazine (CVD) and biotherapy using interleukin-2 and interferon-α. Ann. Oncol. 7: 827-835, 1996.
51) 影下登志郎: 遺伝子治療-悪性黒色腫に対する臨床応用-. Skin Cancer 10: 99-103, 1995.
54) 梅林芳弘: 皮膚腫瘍の陽子線療法. 皮膚臨床 37: 1121-1126, 1995.
P.1394 掲載の参考文献
1) 斎田俊明: メラノーマ・皮膚がん. 臨床腫瘍学(日本臨床腫瘍研究会編) , 癌と化学療法, 東京, 1996, pp. 926-946.
2) 市橋正光: 日光と皮膚癌. 臨床皮膚科 47: 73-79, 1993.
4) Heaton KM: Nonmelanoma skin cancer, The M. D. Anderson surgical oncology handbook. Little, Brown, Boston, 1994, pp. 61-69.
5) がんの統計編集委員会編: がんの統計'97. 財団法人がん研究振興財団, 東京, 1997.
6) 石原和之, 池田重雄, 森 俊二: 皮膚悪性腫瘍の診断と治療指針ならびに全国アンケートの集計. Skin Cancer 9: 7-12, 1994.
8) 斎田俊明: 有棘細胞癌の診断と治療指針. Skin Cancer 9: 69-72, 1994.
9) Sobin LH, Wittekind Ch (ed) : TNM classification of malignant tumours (fifth edition) . Wiley-Liss, New York, 1997, pp. 115-117.
10) 石原和之: 全国アンケートの集計と説明. Skin Cancer 9: 72-77, 1994.
11) 池田重雄, 鈴木 正, 清原祥夫・他: 有棘細胞癌, 基底細胞癌. 癌と化学療法 20: 1293-1301, 1993.
14) 池田重雄, 石原和之, 大浦武彦・他: 有棘細胞癌および悪性黒色腫に対する塩酸イリノテカン (CPT-11) の後期第II相臨床試験. Skin Cancer 8: 503-513, 1993.
15) 小野友道: 基底細胞癌の診断と治療指針. Skin Cancer 9: 78-80, 1994.
16) 森 俊二: Paget病の診断と治療指針. Skin Cancer 9: 32-37, 1994.
17) 大原国章, 大西泰彦, 川端康浩: 乳房外Paget病の診断と治療. Skin Cancer 8: 187-208, 1993.
18) 山崎直也: 皮膚付属器腺癌-特に汗腺癌, 乳房外Paget病-. 癌と化学療法 20: 1302-1307, 1993.
19) 徳田安孝, 小口真司, 山崎百合子・他: 5-FUとCDDPの低濃度持続投与法(low dose FP療法) が奏効した進行期 乳房外Paget病の3例. 日皮会誌 107: 21-27, 1997.
P.1407 掲載の参考文献
1) 脳腫瘍全国統計委員会, 日本病理学会(編) : 脳腫瘍取扱い規約; 臨床と病理カラーアトラス. 金原出版, 東京, 1995, pp. 1-72.
2) 久保田紀彦: 新WHO脳腫瘍分類の改良点と問題点. 脳神経外科23(2) : 97-110, 1995.
6) 久保長生: 髄膜腫の臨床: 第13回日本脳腫瘍病理研究会教育セミナーテキスト. pp. 18-25, 1994.
8) 山下純宏, 山嶋哲盛: 髄膜腫. 脳神経外科 17: 703-711, 1989.
10) Rahn T, Thoren M, Hall K, et al: Stereotactic radiosurgery in Cushing 's disease. Acute radiation effects. Surg. Neurol. 14: 85-90, 1980.
13) 小林達也: ガンマナイフによる間脳下垂体腫瘍の治療. Clin. Neurosci. 12: 627-630, 1994.
16) Yoshida J, Shitara N, Takakura K, et al: Astatistical study of central neurofibromatosis in Japan. Tuberous sclerosis and neurofibromatosis. In: Epidemiology, pathophysiology, biology and management. (eds. by Ishibashi Y, Mori Y) , Elservier Science Publishers, B. V., 1990, pp. 315-321.
20) Kobayashi T: Recent progress in the treatment of craniopharyngioma. Neurosurgeons 3: 101-112, 1984.
23) Walker MD, Strike TA: An evaluation of methyl-CCNU, BCNU and radiotherapy in the treatment of malignant glioma. Proc. A. Assoc. Cancer Res. 17: 163-168, 1976.
26) 片倉隆一, 桜井芳明, 吉本高志: 悪性グリオーマにおける放射線. 化学療法を中心とした治療の現状. Jpn. J. Neuro- surg. (Tokyo) 1: 100-109, 1992.
29) 吉田 純, 若林俊彦, 加藤恭三・他: 悪性脳腫瘍に対するHulFN-β とACNU併用療法の有効性. 癌と化学療法 13 (3) Part-I: 520-524, 1986.
31) 若林俊彦, 吉田 純: 脳腫瘍の集学的治療. 癌の臨床 40(11) : 1089-1094, 1994.
33) 若林俊彦, 吉田 純: 悪性脳腫瘍の放射線治療に対するACNU, インターフェロン併用療法の有効性. Biotherapy 4: 1264-1269, 1990.
36) 野村和弘: 転移性脳腫瘍. 脳神経外科 18(5) : 407-411, 1990.
38) 木田義久, 小林達也, 田中孝幸・他: 転移性脳腫瘍のガンマナイフ治療. 脳神経外科 21(11) : 991-997, 1993.
39) 松谷雅生, 佐野圭司, 高倉公朋・他: 頭蓋内germ cell tumors. Neurosurgeons 3: 83-100, 1984.
40) Teilum G: Classification of endodermal sinus tumor (mesoblastoma vitellium) and so-called “embryonal carcinoma” of the ovary. Acta Pathol. Microbiol. Scand. 64: 407-429, 1965.
44) 全国脳腫瘍統計委員会: Brain Tumor Registry of Japan, vol 9, 1969-1990, 1996.
50) 早川 徹・平賀章壽, 青笹克之, 他: 中枢神経系悪性リンパ腫(高倉公朋監修, 山浦 晶編) , 篠原出版, 東京, 1994.
53) Ater JL, Moore B, Eys JV, et al: Optimizing the treatment of medulloblastoma in very young children. Abstract of 4 th international symposium on pediatric neuro-oncology. Tokyo, 1991, Nov, p. 59.
56) 井上 達, 吉田 純, 景山直樹: Medulloblastomaの予後を左右する因子. 脳神経外科 13(12) : 1283-1289, 1985.
60) 金井秀樹, 永井 肇, 間部英雄・他: CisplatinとEtoposideの併用療法(PE療法) が奏効した髄芽腫の神経管外転移再発例. 癌と化学療法 19(4) : 545-547, 1992.
P.1422 掲載の参考文献
1) 藤本吉秀: 甲状腺結節性病変. 内分泌疾患概念から外科治療まで(藤本吉秀編) , 中外医学社, 東京, 1989, pp. 43-130.
2) 武部晃司, 伊達 学, 山本洋介・他: 甲状腺癌検診の実際とその問題点-甲状腺微小癌の問題を中心として. 外科 58 (6) 651-654, 1996.
3) 甲状腺外科検討会: 甲状腺癌取扱い規約. 第5版, 金原出版, 東京, 1996.
4) 小原孝男: MEN 2家系における甲状腺髄様癌の診断と治療. ホルモンと臨床 44(4) : 337-342, 1996.
8) Williams SD, Birch R, Einhorn LH: Phase II evaluation of doxorubicin plus cisplatin in advanced thyroid cancer: A Southeastern Cancer Study Group Trial Cancer Treat. Rep. 70(3) : 405-407, 1986.
10) 山下共行, 嶋岡勝太郎, 伊藤国彦・他: 甲状腺未分化癌に対する化学療法の意義とその成績. 内分泌外科 9(3) : 213-218, 1992.
11) 筒井一哉: 甲状腺未分化癌の化学療法. 内分泌外科 12(2) : 133-139, 1995.
20) Obara T, Okamoto T, Ito Y, et al: Surgical and medical management of patients with pulmonary metastasis from parathyroid carcinoma. Surgery 114(6) : 1040-1049, 1993.
22) Calandre DB, Chejfec G, Foy BK, et al: Parathyroid carcinoma: Biochemical and pathologic response to DTIC. Surgery 96 (6) : 1132-1137, 1984.
24) 島崎 淳, 市川智彦, 始関吉生・他: 日本統計集・副腎癌. 日本臨牀 51(suppl.) : 766-782, 1993.
28) Cohn K, Gottesman L, Brennan M I Adrenocortical carcinoma. Surgery 100(6) : 1170-1177, 1986.
29) Icard P, Chanpius Y, Andreassian B, et al: Adrenocortical carcinoma in surgically treated patients: A retrospective study on l56 cases by the French Association of Endocrine Surgery. Surgery 112(5) : 972-979, 1992.
31) Pommier RF, Brennan MF: An eleven-year experience with adrenocortical carcinoma. Surgery 112(6) : 963-971, 1992.
36) Kvols LK, Buck M: Chemotherapy of endocrine malignancies: A review. Semin. Oncol. 14(3) : 343-353, 1987.
38) Decker RA, Elson P, Hogan TF, et al: Eastern Cooperative Oncology Group study 1879: Mitotane and adriamycin in patients with advanced adrenocortical carcinoma. Surgery 110(6) : 1006-1013, 1991.
39) van Slooten H, van Oosterom AT: CAP (cyclophosphamide, doxorubicin and cisplatin) regimen in adrenal cortical carcinoma. Cancer Treat. Rep. 67: 377-379, 1983.
40) Burgess MA, Legha SS, Sellin RV: Chemotherapy with cis-platinum and etop 'oside(VP 16) for patients with advanced adrenal cortical-carcinoma (ACC) . Proc. Am. Soc. Clin. Oncol. 12(3) : 188, 1993.
41) Burgess MA: Adrenal cortical carcinoma: The role of adjuvant postoperative chemotherapy. Minerva Endocrinol. 20 (1) : 101-104, 1995.
47) Shapiro B, Copp JE, Sisson JC, et al: Iodine-131 metaiodobenzylguanidine for the locating of suspected pheochromocytoma: Experience in 400 cases. J. Nucl. Med. 26(6) : 576-585, 1985.
48) Hosaka Y, Rainwater LM, Grant CS, et al: Pheochromocytoma: Nuclear deoxyribonucleic acid patterns studied by flow cytometry. Surgery 100(6) : 1003-1008, 1986.
49) Wu LT, Chahinian AP, Baylin SB, et al: Neoplasms of the neuroendocrine system. In: Cancer Medicine(eds. by Holland JF, Frei E, Bast RC, et al) , 4th ed., Williams & Wilkins, Baltimore, 1997.
54) 水野 治: Cyclophosphamide, vincristine, dacarbazineによる化学療法を行った悪性褐色細胞腫の一例と本邦報告 例の文献的考察. 日内分泌会誌 70(9) : 1039-1046, 1994.
56) Shapiro B, Sisson JC, Wieland DM, et al: Radiopharmaceutical therapy of malignant pheochromocytoma with [1311]metaiodo-benzylguanidine: Results from ten years of experience. J. Nucl. Biol. Med. 35(4) : 269-276, 1991.
57) 日下部きよ子, 金谷和子, 金谷信一・他: 131I-MIBGによる悪性褐色細胞腫の治療効果-長期経過観察の結果. 核医学 31 (12) : 1495-1501, 1994.
58) 今村正之: 膵内分泌腫瘍. 第23回日本膵切研究会アンケート集計報告, 1996.
61) Fajans SS, Floyd JC: Hypoglycemia: How to manage a complex disease. Mod. Med. 41: 24-31, 1973.
65) van Heerden JA, Grant CS, Czako PF, et al: Occult functioning insulinomas: Which localizing studies are indicated? Surgery 112 (6) 11010-1015, 1992.
66) Thompson NW, Czako PF, Fitts LL, et al: Role of endoscopic ultrasonography in localization of insulinomas and gastrinomas. Surgery 116(6) : 1131-1138, 1994.
67) 細谷 亮, 加藤雅之, 土井隆一郎. 他: ガストリノーマの診断と治療の進歩. ホルモンと臨床 44(4) : 369-376, 1996.
P.1431 掲載の参考文献
23) Einhorn LH, Williams SD: Chemotherapy of disseminated seminoma. Cancer Clin. Trials 3: 307-313, 1980.
29) Einhorn LH: Testicular cancer as a model for a curable neoplasm. The Richard and Hilda Rosenthal Foundation Award Lecture. Cancer Res. 141: 3275, 1981.
P.1451 掲載の参考文献
6) Bleyer WA: What can be learned about childhood cancer from “Cancer Statistics Review 1973-1988”. Cancer (suppl.) 71 (10) : 3229-3236, 1993.
7) 熊谷昌明, 恒松由記子: 小児悪性腫瘍. 専門医のためのがん治療学レビュー '98(最新主要文献と解説) . 総合医学社, 東京, 1997, pp. 223-227.
11) 味木和喜子, 花井 彩, 津熊秀明・他: 大阪府における小児がんの罹患の動向. 成人病Adult diseases 33: 107-126, 1993.
12) (財) がんの子どもを守る会, 小児がん全国登録委員会: 5年報1979-83.
14) Parkin DM, Stiller CA, Draper GJ, et al (eds.) : “International incidence of childhood cancer, ” IARC Scientific Publications No. 87, IARC, Lyon, 1988.
16) Li FP: Cancer families: human models of susceptibility to neoplasis. Cancer Res. 48: 5381, 1988.
18) Knudson AG Jr: Hereditary cancer, oncogenes and antioncogenes. Cancer Res. 45: 1437-1443, 1985.
19) 恒松由記子: 小児がん臨床遺伝学とがん家系症候群. 日小血会誌 9(6) : 395-403, 1995.
20) 恒松由記子: 家族性腫瘍におけるがん体質の発症前診断に伴う倫理的・法的・社会的諸問題. 癌と化学療法 24(8) : 945-950, 1997.
21) 恒松由記子, 掛江直子: DNAソースとなる試料の採取と保存に関連した倫理的問題. 臨床検査 42(3) : 344-346, 1998.
24) 恒松由記子: 子どものがん. 家庭の医学, 保健同人社, 東京, 1994, pp. 752-758.
25) Pinkerton CR, Cushing P, Sepion B: 3. Making a clinical and pathological diagnosis. Childhood Cancer Management. A Practical Handbook, 1984, pp. 13-27.
26) Steuber CP, Nesbit ME: Clinical assessment and differential diagnosis of the child with suspected cancer. In: Priciple and Practice of Pediatric Oncology (eds. by Pizzo, P. A., Poplack, D. G.) , third ed., Lippencott-Raven, Philadelphia, 1997, pp. 129-139.
27) Triche TJ: Pathology and molecular diagnosis of pediatric malignancies. i. b. i. d. pp. 141-185.
28) Parker BR: Imaging studies in the diagnosis of pediatric malignancies. i. b. i. d. pp. 153-178.
29) 金子安比古: 小児固形腫瘍における染色体異常, がん関連遺伝子. 小児内科 30: 185, 1998.
30) 中田 信, 大木 操: 癌と融合遺伝子. 蛋白質核酸 酵素 42: 1978-1989, 1997.
31) Kenny LB, Reaman GH: Special considerations for the infant with cancer. In: Priciple and Practice of Pediatric Oncology (eds. by Pizzo PA, Poplack DG) , 3「d ed., Lippencott-Raven, Philadelphia, pp. 343-356, 1997.
32) 恒松由記子, 塙 嘉之, 藤本孟男・他: 各種抗悪性腫瘍剤投与による悪心・嘔吐に対するOndansetron注射液の制吐 効果と安全性の検討-小児領域での検討-. 小児科診療 57(10) : 1871-1887, 1994.
33) 恒松由記子, 掛江直子: がんの子どもへのインフォームドコンセントとオープンコミュニケーション. 小児科 38(7) : 891-900, 1997.
34) 東山由美: 白血病の診断・治療とケア: 病名説明後の本人変化. 小児科看護 20: 319-324, 1997.
35) Convention on the Rights of the Child., 1989.
38) 恒松由記子, 田口信行, 佐伯守洋・他: 横紋筋肉腫の晩期障害. 小児外科 26(1) : 99-103, 1994.
39) 恒松由記子: 悪性固形腫瘍患児の晩期障害. 小児期の悪性固形腫瘍-系統的治療を中心に (山本正生編) . 永井書店, 大阪, 1996, pp. 315-328.
40) 恒松由記子: 小児の治療関連2次性白血病. 小児内科 28 (増刊号) : 1192-1196, 1996.
41) 恒松由記子: 小児悪性腫瘍の晩期障害と二次発癌. 小児医学の進歩 '91B. 新小児医学体系. 中山書店, 東京, 1991, pp. 279-293.
47) 小原美江, 斉藤千恵子, 山田ことみ・他: 小児がんにおける疼痛アセスメント. がん看護3(2) : 118-124, 1998.
48) 日本小児外科学会悪性腫瘍委員会: 小児の外科的悪性腫瘍の予後調査結果の報告. 日小外会誌 21: 1222-1251, 1985.
55) Silber JH, Evans AE, Fridman M: Models to predict outcome from childhood neuroblastoma: the role of serum ferritin and tumor histology. Cancer Res. 51: 1426-1433, 1991.
56) Brodeur GM, Castleberry RP: Neuroblastoma. In: Principles and Practice of Pediatric Oncology (eds. by Pizzo PA, Poplack DG. Lippincott-Raven, Philadelphia, 1997, pp. 761-797.
67) Villablanca JD, Khan AA, Avramis VI, et al.
70) 神経芽腫委員会: 神経芽腫マススクリーニングの全国集計結果. 小児がん 32: 103-110, 1995.
73) Lemieux B, et al: The Quebec neuroblastoma screening program: An update. Third International Symposium on Neuroblastoma Screening. Kyoto, September, 1993.
76) 西平浩一・豊田恭徳・井口昌裕: 神経芽腫マススクリーニング陽性例を無治療で経過観察する基準の検討-prospec- tive に長期間無治療で観察した5症例の経験から-. 日小外会誌 31(3) : 424, 1995.
77) 金子道夫・内野純一・武田武夫: 進行神経芽腫の現状と問題点. 小児がん 32(1) : 7-11, 1995.
79) 菊地正悟, 石本浩市, 福渡 靖・他: 神経芽腫マス・スクリーニングの死亡率減少効果測定方法の考按. 日小児会誌 99 (10) : 1855-1858, 1995.
81) Green DM, Breslow NE, Evans I, et al: The relationship between dose schedule and charges for treatment on National Wilms Tumor Study-4. A report from the National Wilms Tumor Study Group. J. Natl. Cancer. Inst.
82) Grundy PE, Telzerow PE, Breslow N, et al: Loss of heterozygosity for chromosomes 16 q and 1 p in Wilms tumors predicts an adverse outcome. Cancer Res. 54: 2331-2333, 1994.
86) 金子安比古: Wilms腫瘍遺伝子とがん. CRC 1: 82-89, 1992.
89) 岡 敏明, 金子安比古: Denys Drash症候群. Mol. Med. 33: 136-137, 1996.
95) 徳田桐子, 高山 順, 大平睦郎: 小児横紋筋肉腫と自家幹細胞移植. 特集 固形腫瘍治療における造血幹細胞移植の現況と問題点. 小児外科 27(10) : 58-63, 1995.
99) Filler RM, Ehrlich PF, Greenberg ML, et al: Preoperative chemotherapy in hepatoblastoma. Surgery 110: 591-597, 1991.
103) Ladenstein R, Lasset C, Pinkerton R, et al: Impact of megatherapy in children with high-risk Ewing 's tumours in complete remission: areport from the EBMT Solid Tumour Registry. Bone Marrow Transplant. 15: 697-705, 1995.
105) Ichikawa H, Shimizu K, Hayashi Y, et al: An RNA-bining protein gene, TLS/FUS, is fudes to ERG in human myeloid leukemia with i (16; 21) chromosomal translocaion. Cancer Res. 54: 2865-2868, 1994.
106) 熊谷昌明, 恒松由記子, 平林万紀子: 小児がんの生存率の改善と長期生存の今後の問題. 化学療法の領域 6: 756-760, 1990.
P.1470 掲載の参考文献
1) Ries LA G, Hankey BF, et al: Cancer statistics Review 1973-1988, Bethesda, Md.: National lnstitute of Health, NIH publication. 91: 2789, 1991.
2) Miller RW: Persons with exceptionally high risk of leukemia. Cancer Res. 27: 2420, 1967.
3) 藤本孟男: 小児白血病の治療. 白血病・悪性リンパ腫(高久史麿編) 改訂第2版, 南江堂, 東京, 1993, pp. 123-138.
5) 藤本孟男: 小児白血病治療の進歩. 日本医事新報 3500: 13-25, 1991.
7) Goldie JH, Coldman AJ: Quantitative model for multiple levels of drug resistance in clinical tumors. Cancer Treat. Rep. 67: 923-931, 1983.
11) Preisler H, Davis RB, et al: Comparison of three remission induction regimens and two postinduction strategies for the treatment of acute non-lymphocytic leukemia: a Cancer and Leukemia Group B study. Blood 69: 1441-1449, 1987.
13) Ritter J, Creutzig U, et al: Treatment results of three consecutive German Childhood AML trials: BFM-78, -83, and -87. Leukemia 6: 59-62, 1992.
14) Clift RA, Thomas ED, et al: The treatment of acute non-lymphocytic leukemia by allogeneic marrow transplantation. Bone Marrow Transplant. 2: 243-258, 1987.
15) Feig SA, Lampkin B, et al: Outcome of BMT during first complete remission of AML: a comparison of two sequential studies by the children 's Cancer Group. Bone Marrow Transplant. 2: 127-135, 1993
16) Degos L: Is acute promyelocytic leukemia a curable disease? Treatment strategy for a long-term survival. Leukemia 8: 911-913, 1994.
18) 佐々木邦明, 藤木孟男: 小児悪性リンパ腫568例の病態と予後. 日小児会誌 91: 690-700, 1987.
19) Donaldson S: Hodgkin 's disease in children. Semin. Oncol. 17: 736-748, 1990.
23) 藤本孟男, 佐々木邦明: 超大量Methotrexateの血中および髄液動態. 癌と化学療法 6: 105-112, 1979.
24) Shimizu H, Fujimoto T, et al: Improved treatment results of non-Hodgkin 's lymphoma in children: a report from the Children 's Cancer and Leukemia Study Group of Japan. Int. J. Hematol. 61: 85-96, 1995.
25) Koizumi S, Fujimoto T: Improvement in treatment of childhood acute lymphoblastic leukemia: a 10-year study by the Children 's Cancer and Leukemia Study Group. Jnt. J. Hematol. 59: 99-112, 1994.
26) Bleyer WA: Principles of cancer chemotherapy in children. Cancer Bull. 44: 46L469, 1992.
P.1491 掲載の参考文献
2) 朝長万左男, 栗山一孝, 市丸道人・他: 原爆被害者に発生した白血病の診断と病型分類の再検討. 広島医学 41: 498- 503, 1988.
3) 厚生省大臣官房統計情報部編: 人口動態統計平成7年. 厚生統計協会, 東京, 1996.
8) Simone JV: Childhood leukemia as a model for cancer research. Cancer Res. 39: 4301-4307, 1979.
10) 清水宏之, 藤本孟男: 小児急性白血病治療の現状. Annual Review血液1992, 中外医学社, 東京, 1992, pp. 130-141.
14) 小川一誠, 太田和雄: 細胞回転. 急性白血病, 金原出版, 東京, 1978, p. 77.
20) Preisler H, Davis RB, Kirshner J, et al: Comparison of three remission induction regimens and two postinduction strategies for the treatment of acute nonlymphocytic leukemia: a cancer and leukemia group B study. Blood 69: 1441-1449, 1987.
22) Buchner TH, Hiddemann W, Wormann B, et al: Longterm effects of prolonged maintenance and of very early intensification chemotherapy in AML: data from AMLCG. Leukemia 6(Suppl) : 68-71, 1992.
25) Cassileth PA, McGlave P, Harrington DP: Comparison of post remission therapy in AML: maintenance versus intensive consolidation therapy versus allogeneic bone marrow transplantation. Proc. Am. Soc. Clin. Oncol. 18: 197, 1989.
28) 大野竜三: 成人急性リンパ性白血病の治療指針. Annual Review 血液, 中外医学社, 1995, pp. 145-156.
34) Nagura E, Yamada K: A controlled randomized clinical trial of adult acute leukemia. Rinsho Ketsueki 26: 821-830, 1985. (in Japanese) .
36) 高橋 功, 稲垣登稔, 仲田浩之・他: 成人急性リンパ性白血病の治療成績. 臨床血液 30: 1167-1170, 1989.
43) Tanimoto M, Miyawaki S, Ino T, et al: Responseoriented individualized induction therapy followed by intensive consolidation and maintenance for adult paitients with acute lymphoblsastic leu kemia. Int. J. Hemotol.: 1998. (in press)
44) Cuttner J, Mick R, Budman DR, et al: Phase III trial of brief intensive treatment of adult acute lymphocytic leukemia comparing daunorubicin and mitoxantrone: a CALGB study. Leukemia 5: 425-431, 1991.
45) Hoelzer D, Thiel E, Ludwig WD, et al: The German multicentre trials for treatment of acute lymphoblastic leukemia in adults. Leukemia 6(Suppl. 2) : 175-177, 1992.
46) Bassan R, Battista R, Rohatiner AZS, et al: Treatment of adults acute lymphoblastic leukaemia (ALL) over a 16 year period. Leukemia 6(Suppl. 2) : 186-190, 1992.
47) Ohno R: Current progress in the treatment of adult acute leukemia in Japan. Jpn. J. Clin. Oncol. 22: 85-97, 1993.
52) Ohno R, Yoshida H, Fukutani H, et al: Multi-institutional study of all-trans retinoic acid as a differentiation therapy of acute promyelocytic leukemia. Leukemia 7: 1722-1727, 1993.
59) 長尾 大: 我が国における造血幹細胞移植例の全国集計(1993) . 今日の移植 7: 93-101, 1994.
65) Suzuki H, Ota K, Ohno R, et al: Recent trends in the treatment and prognosis of adult leukemia with characteristics of patients in Japan: transition during the fifteen years from 1971 to 1985. JPn. J. Clin. Oncol. 19: 338-347, 1989.
67) Kantarijan HM, Smith TL, O'Brien S, et al: Prolonged survival in chronic myelogenous leukemia after cytogenetic response to interferon-α therapy. Ann. Intern. Med. 122: 254-261, 1995.
70) Yoshida Y, Stephenson J, Mufti GJ: Myelodysplastic syndromes from morphology to molecular biology. Part I. Classification, natural history and cell biology of myelodysplasia. Int. J. Hematol. 57: 87-97, 1993.
79) 上田龍三: 成人の難治性白血病の分子生物学的機構の解明と薬物療法の確立に関する研究. 平成5年度厚生省がん研究助成金による研究報告集, 国立がんセンター, 東京, 1995, pp. 290-298.
P.1503 掲載の参考文献
1) 田島和夫, 広瀬加緒瑠, 黒石哲夫: 悪性リンパ腫-わが国の記述免疫学的特徴-. 医学のあゆみ 175: 863-868, 1995.
2) Lukes RJ, Craver LF, Hall TC, et al: Report of the Nomenclature Committee. Cancer Res. 26: 1311, 1966.
3) von Wasielewski R, Mengel M, Fischer R, et al: Classical Hodgkin 's disease: clinical impact of the immunophenotype. Am. J. Pathol. 15: 1123-1130, 1997.
7) Carbone PP, Kaplan HS, Musshoff K, et al: Report of the committee on Hodgkin 's disease staging classification. Cancer Res. 31: 1860-1861, 1971.
22) Santoro A, Viviani C, Villarreal CJR, et al: Salvage chemotherapy in Hodgkin 's disease irradiation failures: superiority of doxorubicin-containing regimens over MOpp. Cancer Treat. Rep. 70: 343-348, 1986.
24) Pfreundschuh MG, Schoppe WD, Fuchs R, et al: Lomustine, etoposide, vindesine, and dexamethasone (CEVD) in Hodgkin 's lymphoma refractory to cyclophosphamide, vincristine, procarbazine, and prednisone (COPP) and doxorubicin, bleomycin, vinblastine, and dacarbazine(ABVD) : a multicenter trial of the German Hodgkin Study Group. Cancer Treat. Rep. 71: 1203-1207, 1987.
P.1526 掲載の参考文献
2) Devesa SS, Fears T: Non-Hodgkin 's lymphoma time trends: United States and international data. Cancer Res. 52(Suppl.) : 5432-5440, 1992.
7) T・Bリンパ系腫瘍研究グループ: 第5次成人T細胞白血病/リンパ腫(ATL) 全国実態調査の報告-第4次全国実態調査の評価-. 癌の臨床 38: 405-416, 1992.
9) Hangaishi A, Ogawa S, Imamura N, et al: Inactivation of multiple tumor-suppressor genes involved in negative regulation of the cell cycle, MTS 1/p l61NK4A, MTS 2/p 15iNK4B, p 53, and Rb genes in primary lymphoid malignancies. Blood 87: 4949-4958, 1996.
12) Okamoto T, Ohno Y, Tsugane S, et al: Multi-step carcinogenesis model for adult T-cell leukemia. Jpn. J. Cancer Res. 80: 191-195, 1989.
13) Diamandidou E, Cohen PR, Kurzrock R: Mycosis fungoides and S6zary syndrome. Blood 88: 2385-2409, 1996.
15) Kikuchi A, Nishikawa T, Ikeda Y, et al: Absence of human T-lymphotropic virus type I in Japanese patients with cutaneous T-cell lymphoma. Blood 89: 1529-1532, 1997.
18) Aozasa K, Yang W-1, Lee YB, et al: Lethal midline granuloma in Seoul, Korea and Shanghai, China. Int. J. Cancer 52: 673-674, 1992.
24) Cesarman E, Moore PS, Rao PH, et al: In vitro establishment and characterization of two acquired immunodeficiency syndrome-related lymphoma cell lines (BC-1 and BC-2) containing Kaposi 's sarcoma-associated herpesvirus-like (KHSV) DNA sequences. Blood 86: 2708-2714, 1995.
27) Fukayama M, Ibuka T, Hayashi Y, et al: Epstein-Barr virus in pyothorax-associated pleural lymphoma. Am. J. Pathol. 143: 1044-1049, 1993.
28) Sasajima Y, Yamabe H, Kobashi Y, et al: High expression of the Epstein-Barr virus latent protein EB nuclear antigen-20n pyothorax-associated lymphomas. Am. J Pathol. 143: 1280-1285, 1993.
37) Non-Hodgkin 's Lymphoma Pathologic Classification Project. National Cancer Institute sponsored study of classifications of non-Hodgkin 's lymphomas: Summary and descriptions of a Working Formulation for clinical usage. Cancer 49: 2112-2135, 1982.
38) 下山正徳向井 清, 菊池昌弘・他: 専門病理医による非ポジキンリンパ腫の病理診断とホルマリン固定標本による T・Bマーカー免疫診断の一致率: LCPP(Lymphoma Clinico-pathology Panel) による共同研究. 癌の臨床 39: 739-765, 1993.
40) 下山正徳, 向井 清, 菊池昌弘・他: 専門病理医の中央診断をうけた非ポジキンリンパ腫447例の重要な予後因子と予後予測に有用な臨床病理予後分類(Lymphoma Clinico-pathological Prognostic Classification: LCP分類) とLCP スキーマ. 日本リンパ網内系学会誌 38: 41-55, 1998.
41) Harris NL, Jaffe ES, Stein H, et al: A revised European-American classification of lymphoid neoplasms: A proposal form the International Lymphoma Study Group. Blood 84: 1361-1392, 1994.
43) Weisenburger DD, Armitage JO: Mantle cell lymphoma: An entity comes of age. Blood 87: 4483-4494, 1996.
44) Shimoyama M, Minato K, Saito H, et al: Immunoblastic lymphadenopathy (IBL) -like T-cell lymphoma. Jpn. J. Clin. Oncol. 9 (SupPl. 1) : 347, 1979.
45) Tobinai K, Minato K, Ohtsu T, et al: Clinicopathologic, immunophenotypic, and immunogenotypic analyses of immunoblastic lymphadenopathy-like T-cell lymphoma. Blood 72: 1000-1006, 1988.
46) Uchiyama T, Yodoi J, Sagawa K, et al: Adult T-cell leukemia: Clinical and hematologic features of 16 cases. Blood 50: 481-492, 1977.
47) Stein H, Mason D, Gerdes J, et al: The expression of the Hodgkin 's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: Evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells. Blood 66: 848, 1985.
48) Fisher RI, Dahlberg S, Nathwani BN, et al: A clinical analysis of two indolent lymphoma entities: Mantle cell lymphoma and marginal zone lymphoma (including the mucosa-associated lymphoid tissue and monocytoid Bcell subcategories) : A Southwest Oncology Group Study. Blood 85: 1075-1082, 1995.
49) Melnyk A, Rodriguez A, Pugh WC, et al: Evaluation of the Revised European-American Lymphoma Classification confirms the clinical relevance of immunophenotype in 560 cases of aggressive non-Hodgkin 's lymphoma. Blood 89: 4514-4520, 1997.
50) Pittaluga S, Bijnens L, Teodorovic I, et al: Clinical analysis of 670 cases in two trials of the European Organization for the Research and Treatment of Cancer Lymphoma Cooperative Group subtyped according to the revised European-American Classification of Lymphoid Neoplasms: AComparison with the Working Formulation. Blood 87: 4358-4367, 1996.
51) The Non-Hodgkin 's Lymphoma Classification Project: A clinical evaluation of the International Lymphoma Study Group Classification of non-Hodgkin 's lymphoma. Blood 89: 3909-3918, 1997.
52) The International Non-Hodgkin 's Lymphoma Prognostic Factors Project: Apredictive model for aggressive non-Hodgkin 's lymphoma. N. Engl. J Med. 329: 987-994, 1993.
53) Hiddemann W, Longo DL, Coiffier B, et al: Lymphoma classification: The gap between biology and clinical management is closing. Blood 88: 4085-4089, 1996.
54) Shipp MA, Mauchi PM, Harris NL: Non-Hodgkin 's lymphoma. In: Cancer. Principles and Practice of Oncology, 5th edition (DeVita VT Jr, et al, eds.) , Lippincott-Raven, Philadelphia, PA, 1997, pp. 2165-2220.
55) DeVita VT Jr, Jaffe ES, Mauchi PM, et al: Lymphocytic lymphomas. In: Cancer. Principles and Practice of Oncology, 3rd edition (DeVita VT Jr, et al, eds.) , Lippincott-Raven, Philadelphia, PA, 1989, pp. 1741-1798.
61) Coco FL, Gainado G, Louie DC, et al: p53 mutations are associated with histologic transformation of follicular lymphoma. Blood 82: 2289-2295, 1993.
62) Uchida T, Watanabe T, Kinoshita T, et al: Mutational analysis of the CDKN 2(MTS 1/p 16ink4A) gene in primary B-cell lymphomas. Blood 86: 2724-2731, 1995.
66) Carbone PP, Kaplan HS, Musshoff K, et al: Report of the committee on Hodgkin 's disease staging. Cancer Res. 31: 1860-1861, 1971.
67) Coltman CA, Luce JK, McKelvy EM, et al: Chemotherapy of non-Hodgkin 's lymphoma: 10 years experience in the Southwest Oncology Group. Cancer Treat. Rep. 61: 1067-1078, 1977.
70) Glick JH, Kim K, Earle J, et al: An ECOG randomized phase III trial of CHOP versus CHOP plus radiotherapy for intermediate grade early stage non-Hodgkin 's lymphoma. Proc. Am. Soc. Clin. Oncol. 14: 391, 1995 (Abstr.) .
73) Tobinai K, Shimoyama M, Minato K, et al: Japan Clinical Oncology Group (JCOG) phase II trial of second generation "LSG 4 Protocol" in aggressive T-and B-lymphoma: A new predictive model for T-and B-lymphoma. Proc. Am. Soc. Clin. Oncol. 13: 378, 1994 (Abstr.) .
80) Jerkeman M, Cavallin-Stahl E, Hagberg H, et al: CHOP versus MACOP-B in high grade malignant non-Hodgkin 's lymphoma: A prospective randomized study by the Nordic Lymphoma Study Group. Ann. Oncol. 7 (Suppl. 3) : 24, 1996.
83) Paryani SB, Hoppe RT, Cox RS, et al: Analysis of non-Hodgkin 's lymphomas with nodular and favorable histologies, stages I and II. Cancer 52: 2300-2307, 1983.
89) Solal-Celigny P, Lepage E, Brousse N, et al: Recombinant interferon alpha-2 b combined with a regimen containing doxorubicin in patients with advanced follicular lymphoma. N. Engl. J. Med. 329: 1608-1614, 1993.
90) Peterson BA, Petroni G, Oken MM, et al: Cyclophosphamide versus cyclophosphamide plus interferon alfa-2 b in follicular low grade lymphomas: A preliminary report of an intergroup trial (CALGB 8691 and EST 7486) . Proc. Am. Soc. Clin. Oncol. 12: 366, 1993 (Abstr. #1240) .
91) Dana BW, Unger J, Fisher RI, et al: A randomized study of alpha-interferon consolidation in patients with lowgrade lymphoma who have responded to ProMACE-MOPP (day 1-8) (SWOG 8809) . Proc. Am. Soc. Clin. Oncol. 17: 3a, 1998(Abstr. #10) .
92) Rohatiner AZS, Gregory W, Peterson B, et al: A meta-analysis of randomized trials evaluating the role of interferon as treatment for follicular lymphoma. Proc. Am. Soc. Clin. Oncol. 17: 4a, 1998 (Abstr. #11) .
94) Salal-Celigny P, Brice P, Brousse N, et al: Phase II trial of fludarabine monophosphate as first-line treatment in patients with advanced follicular lymphoma: Amulticenter study by the Groupe d 'Etude des Lymphomes de PAdulte. J. Clin. Oncol. 14: 514-519, 1996.
99) Reff ME, Carner K, Chambers KS, et al: Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD 20. Blood 83: 435-445, 1994.
100) Maloney DG, Lilies TM, Czerwinski DK, et al: Phase I clinical trial using escalating single-dose infusion of chimeric anti-CD 20 monoclonal antibody (IDEC-C 2 B 8) in patients with recurrent B-cell lymphoma. Blood 84: 2457-2466, 1994.
102) Maloney DG, Grillo-Lopez AJ, White CA, et al: IDEC-C 2 B 8 (Rituximab) anti-CD 20 monoclonal antibody therapy in patients with relapsed low-grade non-Hodgkin 's lymphoma. Blood 90: 2188-2195, 1997.
103) Tobinai K, Kobayashi Y, Narabayashi M, et al: Feasibility and pharmacokinetic study of chimeric anti-CD 20 monoclonal antibody (IDEC-C 2 B 8, rituximab) in relapsed B-cell lymphoma. Ann. Oncol. 9: 527-534, 1998.
105) Kaminski MS, Zasadny KR, Francis IR, et al: Radioimmunotherapy of B-cell lymphoma with [1311] anti-B1 (anti-CD 20) antibody. N. Engl. J. Med. 329: 459-465, 1993.
110) Knox SJ, Goris ML, Trisler K, et al: Yttrium-90-1abeled anti-CD 20 monoclonal antibody therapy of recurrent B-cell lymphoma. Clin. Cancer Res. 2: 457-470, 1996.
112) Soussain C, Patte C, Ostronoff M, et al: Small noncleaved cell lymphoma and leukemia in adults: A retrospective study of 65 adults treated with the LMB pediatric protocols. Blood 85: 664-574, 1995.
116) Shimoyama M: Chemotherapy of ATL In: Adult T-Cell Leukemia(ed. by ed Takatsuki K) : Oxford University Press, Oxford, 1994, pp. 221-237.
117) Tobinai K, Shimoyama M, Tajima K, et al: Deoxycoformycin-containing combination chemotherapy for adult T-cell leukemia-lymphoma. Proc. Am. Soc. Clin. Oncol. 14: 390, 1995(Abstr.) .
120) Waldman TA, Goldman CK, Bongiovanni KF, et al: Therapy of patients with human T-cell lymphotropic virus I-induced adult T-cell leukemia with anti-Tac, a monoclonal antibody to the receptor for interleukin-2. Blood 72: 1805-1816, 1988.
121) Waldmann TA, White JD, Carrasquillo JA, et al: Radioimmunotherapy of interleukin-2 Rα-expressing adult T-cell leukemia with yttrium-90-labeled anti-Tac. Blood 86: 4063-4075, 1995.
128) Velasquez WS, Cabanillas F, Salvador P, et al: Effective salvage therapy for lymphoma with cisplatin in combination with high-dose ara-C and dexamethazone (DHAP) . Blood 71: 117-122, 1988.
135) Armitage JO: Bone marrow transplantation in the treatmellt of patients with lymphoma. Blood 73: 1749-1758, 1989.
136) Schmitz N, Linch DC, Dreger P, et al: Randomised trial of filgrastim-mobilised peripheral blσod progenitor cell transplantation versus autologous bone-marrow transplantation in lymphoma patients. Lancet 3471353-357, 1996.
145) Gisselbrecht C, Lepage E, Mortel P, et al: Short and intensified treatment with autologous stem-cell transplantation versus ACVB regimen in poor prognosis aggressive lymphoma: Prognostic factors of induction failure. Ann. Oncol. 7(SuppL 3) : 18, 1996.
148) Nademanee A, Monila A, 0 'Donnell MR, et al: Results of high-dose therapy and autologous bone marrow/stem cell transplantation during remission in poor-risk intermediate-and high-grade lymphoma: International index high and high-intermediate risk group. Blood 90: 3844-3852, 1997.
P.1560 掲載の参考文献
1) Herrinton LJ, Weiss NS, Olshan AF: The epidemiology of myeloma. In: Myeloma. Biology and Management (eds. by Malpas JS, et al) , Oxford Univ. Press, Oxford, 1995, pp. 127-168.
2) 戸川 敦, 天野正道, 高久史麿: 我が国の多発性骨髄腫の最近の動向. 日本医事新報 3462: 31-34, 1990.
4) Kyle RA: Multiple myeloma and other plasma cell disorders. In: Hematology. Basic principles and practice (eds. by Hoffman R, et al) , 2nd Ed, Churchill Livingstone Inc, New York, 1995, pp. 1354-1374.
11) Alexanian R: Localized and indolent myeloma. Blood 56: 521-525, 1980.
12) Malpas JS: Clinical presentation and diagnosis. In: Myeloma. Biology and Management(eds. by Malpas JS, et al, Oxford Univ. Press, Oxford, 1995, pp. 169-190.
14) Lai JL, Zandecki M, Mary JY, et al: Improved cytogenetics in multiple myeloma: A study of 151 patients including 117 patients at diagnosis. Blood 85: 2400-2497, 1995.
16) Tesch H, Diehl V, Kube D: Molecular biology of myeloma. In: Myeloma. Biology and Management (eds, by Malpas JS, et al) , Oxford Univ. Press, Oxford, 1995, pp. 50-62.
18) Fractif M, Zandecki M, Lai JL, et al: Interphase fluorescence in sitza hybridization (FISH) as a powerful tool for the detection of aneuploidy in multiple myeloma. Br. J. Haematol. 90: 693, 1995.
19) Drach J, Angerler J, Schuster J, et al: Interphase fluorescence in situ hybridization identifies chromosomal abnormalities in plasma cells from patients with monoclonal gammopathy of undetermined significance. Blood 86: 3915-3921, 1995.
20) Garcia-Sana R, Orfao A, Gonaalez M, et al: Prognostic implications of DNA aneuploidy in 156 untreated multiple myeloma patients. Br. J. Haematol. 90: 106-112, 1995.
21) Sawyer JR, Tricot G, Mattox S, et al: Jumping translocations of chromosome lq in multiple myeloma: evidence for a mechanism involving decondensation of pericentromeric heterochromatin. Blood 91: 1732-1741, 1998.
23) Nishida K, Tamura A, Nakazawa N, et al: The immunoglobulin heavy chain gene is frequently involved in chromosomal translocations in multiple myeloma and plasma cell leukemia detected by is situ hybridization. Blood 90: 526-534, 1997.
25) Tricot G, Barlogie B, Jagannath S, et al: Poor prognosis in multiple myeloma is associeated only with partial or complete deletion of chromosome 130r abnormalities involving llq and not with other karyotype abnormalities. Blood 86: 4250-4256, 1995.
29) Ong F, NieuwkooP JA, De Groot-Swings GMJS, et al: Bcl-2 protein expression is not related to short survival in multiple myeloma. Leukemia 9: 1282-1284, 1995.
30) Tsuchiya H, Epstein J, Selvanayagam P, et al: Correlated flow cytometric analysis of H-ras p21 and nuclear DNA in multiple myeloma. Blood 72: 796-800, 1988.
33) Neri A, Baldini L, Trecca D, et al: p53 gene mutations in multiple myeloma are associated with advanced forms of malignancy. Blood 81: 128-135, 1993.
34) Juge-Morineau N, Mellerin MP, Francois S, et al: High incidence of deletions but infrequent inactivation of the retinoblastoma gene in human myeloma cells. Br. J. Haematol. 91: 664-667, 1995.
35) Ng MHL, Chung KW, Lo KW, et al: Frequent hypermutation of p16 and p15 genes in multiple myeloma. Blood 89: 2500-2506, 1997.
36) Hallek M, Bergsagel PL, Anderson KC: Multiple myeloma: increasing evidence for a multistep transformation precess. Blood 91: 3-21, 1998.
38) Klein B, Zhang X-G, Lu Z-Y, et al: Interleukin-6 in human multiple myeloma. Blood 85: 863-872, 1995.
42) Klein B, Zhang X-G, Jourdan M, et al: Paracrine rather than autocrine regulation of myeloma cell growth and differentiation by interleukin-6. Blood 73: 517-526, 1989.
44) Lu ZY, Zhang XG, Rodriguez C, et al: Interleukin-10 is a proliferation factor but not a differentiation factor for human myeloma cells. Blood 85: 2521-2527, 1995.
45) Retting MB, Ma HJ, Vescio RA, et al: Kaposi 's sarcoma-associated herpesvirus infection of bone marrow dendritic cells from multiple myeloma patients, Science 276: 1851-1854, 1997.
49) Juge-Morineau N, Francois S, Puthier D, et al: The gp130 family cytokines IL-6, LIF, OSM but not IL-11 can reverse the anti-proliferative effect of dexamethasone on human myeloma cells. Br. J. Haematol. 80: 707-710, 1995.
50) Lemoli RM, Fortuna A, Grande A, et al: Expression and functional role of c-kit ligand (SCF) in human multiple myeloma cells. Br. J. Haematol. 88: 700-709, 1994.
51) Zhang XG, Bataille R, Jourdan M, et al: Granulocyte-macrophage colony-stimulating factor synergizes with interleukin-6 in supporting the proliferation of human myeloma cells. Blood 76: 2599-2605, 1990.
52) Klein B: Cytokines, cytokine receptors, transduction signals and oncogenes in multiple myeloma. Semin. Hematol. 32: 4-19, 1995.
53) Anderson KC, Jones RM, Morimoto C, et al: . Response patterns of purified myeloma cells to hematopoietic growth factors. Blood 73: 1915-1924, 1989.
56) Durie BGM, Grogan TM: CALLA-positive myeloma: An aggressive subtype with poor survival. Blood 66: 229-232, 1985.
58) Grogan TM, Huang N, Harada H, et al: Myelomonocytic antigen positive multiple myeloma. Blood 73: 763-769, 1993.
60) Uchiyama H, Barut BA, Chauhan D, et al: Characterization of adhesion molecules on human myeloma cell lines. Blood 80: 2306-2314, 1992.
61) Shibayama H, Tagawa S, Hattori H, et al: Laminin and fibronectin promote the chemotaxis of human malignant plasma cell lines. Blood 86: 719-725, 1995.
63) Kawano MM, Huang N, Harada H, et al: Identification of immature and mature myeloma cells in the bone marrow of human myelomas. Blood 82: 564-570, 1993.
64) Uchiyama H, Barut BA, Mohrbacher AF, et al: Adhesion of human myeloma cell lines to bone marrow stroma cells stimulates interleukin-6 secretion. Blood 82: 3712-3720, 1993.
65) Hamiltcn MS, Ball J, Bromidge E, et al: Surface antigen expression of human neoplastic plasma cells includes molecules associated with lymphocyte recirculation and adhesion. Br. J. Haematol. 78: 60-65, 1991.
67) Ahsmarm EJM, Lokhorst HM, Dekker AW, et al: Lymphocytic function-associated antigen-1 expression on plasma cells correlates with tumor growth in multiple myeloma. Blood 79: 2068-2075, 1992.
68) Ridley RC, Xiao H, Hata H, et al: Expression of syndecan regulates human myeloma plasma cell adhesion to typeIcollagen. Blood 81: 767-774, 1993.
69) Dhodapkar MV, Abe E, Theus A, et al: Syndecan-1 is a multifunctional regulator of myeloma pathobiology: control of tumor cell survival, growth, and bone cell differentiation. Blood 91: 2679-2688, 1998.
70) Tong AW, Zhang B-q, Mues G, et al: Anti-CD40 antibody binding modulates human multiple myeloma clonogenicity in vitro. Blood 84: 3026-3033; 1994.
71) Shima Y, Nishimoto N, Ogata A, et al: Myeloma cells express Fas antigen/APO-1(CD95) but only some are sensitive to anti-Fas antibody resulting in apoptosis. Blood 85: 757-764, 1995.
73) Kaiser U, Jaques G, Havemann K, et al: Serum NCAM: A potential new prognostic marker for multiple myeloma. Blood 83: 871-873, 1994.
75) Berenson J, Wong R, Kim K, et al: Evidence of peripheral blood B lymphocyte but not T lymphocyte involvement in multiple myeloma. Blood 70: 1550-1553, 1987.
76) Bakkus MHC, Heirman C, Van Riet I, et al: Evidence that multiple myeloma Ig heavy chain VDJ genes contain somatic mutations but show no intraclonal variation. Blood 80: 2326-2335, 1992.
78) Corradini P, Boccadoro M, Voena C, et al: Evidence for a bone marrow B cell transcribing malignant plasma cell VDJ joined to Cμsequence in immunoglobulin (IgG) -and IgA-secreting multiple myelomas. J. Exp. Med. 178: 1091-1096, 1993.
79) Cremer FW, Kiel K, Sucker C, et al: A rationale for positive selection of peripheral blood stem cells in multiple myeloma: highly purified CD34+ cell fraction of leukapheresis products do not contain malignant cells. Leukemia 11(suppl. 5) : S41-46, 1997.
81) Foerster J: Multiple myeloma. In: Wintrobe 's Clinical Hematology(eds. by Lee GR, et al) , 9th Ed. Lea & Febiger, Philadelphia, 1993, pp. 2219-2249.
82) Shulman LN: Plasma cell diseases and related disorders. In: Blood: Principles and Practice of Hematology (eds. by Hardin RI, et al) , Lippincott Company, Philadelphia, 1995, pp. 885-913.
85) Kawano M, Yamamoto I, Iwato K, et al: Interleukin-1 beta rather than lymphotoxin as the major bone resorbing activity in human multipe myeloma. Blood 73: 1646-1649, 1989.
87) Greaves MF, Habeshaw JA, Stansfeld AG: Lymphoproliferative disorders. In: Atlas of blood cells (eds. by Zucker-Franklin D, et al) , Edi. Ermes, Milano, 1981, pp. 409-524.
88) 三輪哲義: 多発性骨髄腫の細胞形態. 日本臨牀 53: 538-542, 1995.
89) Greipp PR, Raymond NM, Kyle RA, et al: Multiple myeloma: Significance of plasmablastic subtype in morphological classification. Blood 65: 305-310, 1985.
92) 梅田正法, 津布久雅彦: 多発性骨髄腫 最近の画像診断. 日本臨牀 53: 636-641, 1995.
94) Kyle RA: Diagnosis and management of multiple myeloma and related disorders. Prog. Hematol. 14: 257-282, 1986.
96) Durie BGM, Salmon SE: Multiple myeloma, macrogrobulinemia and monoclonal gammopaties. In: Recent advances in hematology (eds. by Hoffbrand AV, et al) , Churchill-Livingstone, Edinburgh, 1977, pp. 243-261.
101) Alexanian R, Bonnet J, Gehan E, et al: Combination chemotherapy for multiple myeloma. Cancer 30: 382-389, 1979.
102) Chronic Leukemia-Myeloma Task Force, National Cancer Institute: Proposed guidelines for protocol studies: II, Plasma cell myeloma. Cancer Chemother. Rep. 4(suppl.) : 145-158, 1973.
104) 今村幸雄: 骨髄腫. 癌の臨床 27: 1067-1074, 1981.
106) Hardin J, MacLeod S, Grigorieva 1, et al: Interleukin-6 prevents dexamethasone-induced myeloma cell growth. Blood 84: 3063-3070, 1994.
124) Finnish Leukemia Group: Combination chemotherapy MOCCA in resistant and relapsing myeloma. Eur. J. Haematol. 48: 37-40, 1992.
126) Adam Z, Elbl L, Vorliek J, et al: Treatment of refractory multiple myeloma with vincristine, adriamycin, dexamethasone, and with repeated application of cyclophosphamide. Acta Med. Austriaca 21: 111-115, 1994.
136) Avvisati G, Mandelli F: The role of interforon-α in the management of myelomatosis. Hematol. Oncol. Clin. North Am. 6: 395-405, 1992.
138) Osterborg A, Bjorkholm M, Bjoreman M, et al: Natural interferon-α in combination with melphalan/prednisone versus melphalan/prednisone in the treatment of multiple myeloma stage III and III: A randomized study from the myeloma group of central Sweden. Blood 81: 1428-1434, 1993.
139) Corrado C, Flores A, Pavlovsky S, et al: Randomized trial of melphalan (L-PAM) -Prednisone (PRED) with or without recombinant alpha 2 interferon(rα21FN) in multiple myeloma. Proc. Am. Soc. Clin. Oncol. 10: 27 Meet, 304, 1991.
143) Miguel JFS, Moro M, Blade J, et al: Combination of interferon and dexamethasone in refractory multiple myeloma. Haematol. Oncol. 8: 185-189, 1990.
144) Palumbo A, Boccadolo M, Garino LA, et al: Interferon plus glucocorticoids as intensified maintenance therapy prolongs tumor controls in relapsed myeloma. Acta Haematol. 90: 71-76, 1993.
145) Alexanian R, Barlogie B, Gutterman J: α-interferon combination therapy of resistant myeloma. Am. J. Clin. Oncol. 14: 188-192, 1991.
147) Cohen AM, Meytes D, Many A, et al: Interferon alfa-2b with VMCP for induction in multiple myeloma: The Israel myeloma cooperative group experience. Isr. J. Med. Sci. 31: 604-610, 1995.
148) Aviles A, Alatriste S, Talavera A, et al: Altemating combination chemotherapy and interferon improves survival in poor prognosis multiple myeloma. Clin. Oncol. 7: 97-101, 1995.
150) Oken MM, Kyle RA, Greipp PR, et al: Complete remission induction with combined VBMCP chemotherapy and interferon (rIFN α 2b) in patients with multiple myeloma. Leuk. Lymphoma 20: 447-452, 1996.
151) 木谷照夫: 骨髄腫の基礎と臨床. IFNを含む新しい併用療法. 臨床血液 34: 455-459, 1993.
152) 木谷照夫: 造血器腫瘍-どのように診断し治療するか. 多発性骨髄腫. 臨床血液 36: 471-479, 1995.
157) Barlolgie B, Jagannath S, Epstein J, et al: Biology and therapy of multiple myeloma in 1996. Semin. Hematol. 34 (Suppl. 1) : 67-72, 1997.
167) Sonneveld P, Lokhorst HM, Vosseveld P: Drug resistance in multiple myeloma. Semin. Hematol. 34: 34-39, 1997.
168) Merlin J-L, Guerci A, Marchal S, et al: Comparative evaluation of S9788, verapamil, and cyclosporin A in K562 human leukemia cell lines and in P-glycoprotein-expressing samples from patients with hematologic malignancies. Blood 84: 262-269, 1994.
180) Sanders PW: Pathogenesis and treatment of myeloma kidney. J. Lab. Clin. Med. 124: 484-488, 1994.
181) Joshua DE, Snowdon L, Gibson J, et al: Multiple myeloma: Plateau phase revisited. Hematol. Rev. 5: 59-66, 1991.
184) Greipp PR, Lust JA, O'Fallon WM, et al: Plasma cell labeling index and β2-microglobulin predicts survival independent of thymidine kinase and C-reactive protein in multiple myeloma. Blood 81: 3382-3387, 1993.
188) Gherardi RK, B61ec L, Fromont G, et al: Elevated levels of interleukin-1β (IL-1β) and IL6 in serum and increased production of IL-1β mRNA in lymph nodes of patients with polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes (POEMS) syndrome. Blood 83: 2587-2593, 1994.
189) Franklin EC: Amyloidosis. In: Williams Hematology (eds. by Beutler E, et al) , 4th Ed. McGraw-Hill, Inc, New York, 1990, pp. 1112-1118.
P.1581 掲載の参考文献
1) Greco FA, Hainsworth JD: Cancer of unknown primary site. In: Cancer: Principles & Practice of Oncology (eds. by Devita Jr VT, Hellman S, Rosenberg SA) , 4th Ed., J. B. Lippincott, Philadelphia, 1993, pp. 2072-2092.
4) 万代光一, 森脇昭介, 山上啓太郎・他: 剖検例を対象とした原発不明癌症例の検討. 臨床病理 42: 75-82, 1994.
12) Mackay B, Ordonez NG: Pathological evaluation of neoplasms with unknown primary tumor site. Semin. Oncol. 20: 206-228, 1993.
13) Leonard RJ, Nystrom JS: Diagnostic evaluation of patients with carcinoma of unknown primary tumor site. Semin. Oncol. 20: 244-250, 1993.
23) de Braud F, Al-Sarraf M: Diagnosis and management of squamous cell carcinoma of unknown primary tumor site of the neck. Semin. Oncol. 20: 273-278, 1993.
28) Sears D, Hajdu SI: The cytologic diagnosis of malignant neoplasms in pleural and peritoneal effusions. Acta Cytol. 31: 85-97, 1987.
29) DiBonito L, Falconieri G, Colautti I, et al: The positive peritoneal effusion. A retrospective study of cytopathologic diagnoses with autopsy confirmation. Acta Cytol. 37: 483-488, 1993.
33) Fromm G-L, Gershenson DM, Silva EG: Papillary serous carcinoma of the peritoneum. Obstet. Gynecol. 75: 89-95, 1990.
34) Svastics E, R6nay P, Bod6 M: Occult breast cancer presenting with axillary metastasis. Eur. J. Surg. Oncol. 19(Suppl. 1) : 575-580, 1993.
39) Ruddon RW, Norton SE: Use of biological markers in the diagnosis of cancers of unknown primary tumor. Semin. Oncol. 20: 251-260, 1993.
44) Ilson DH, Motzer RJ, Rodriguez E, et al: Genetic analysis in the diagnosis of neoplasms of unknown primary tumor site. Semin. Oncol. 20: 229-237, 1993.
70) Mohit-Tabatabai MA, Dasmahapatra KS, Rush BF, et al: Management of squamous cell carcinoma of unknown origin in cervical lymph nodes. Am. Surg. 52: 152-154, 1986.
73) Muggia FM, Baranda J: Management of peritoneal carcinomatosis of unknown primary tumor site. Semin. Oncol. 20: 268-272, 1993.
74) Young RC, Perez CA, Hoskins WJ: Cancer of the ovary. In: Cancer: Principles & Practice of Oncology(eds. by Devita VT, Hellman S, Rosenberg SA) , 4th Ed., JB. Lippincott, Philadelphia, 1993, pp. 1226-1263.
81) Sporn JR, Greenberg BR: Empirical chemotherapy for adenocarcinoma of unknown primary tumor site. Semin. Oncol. 20: 261-267, 1993.
83) Walach N, Horn Y: Combination chemotherapy in the treatment of adenocarcinoma of unknown primary origin. Cancer Treat. Rep. 71: 605-607, 1987.
85) Ahlgren JD, Bern M, Booth B, et al: Protracted infusional 5-FU(PIF) : An active, well-tolerated regimen in metastatic adenocarcinoma of undetermined primary (AUP) . Amid-atlantic oncology program (MAOP) study. Proc. ASCO 12: 401, 1993.
88) Milliken ST, Tattersall MHN, Woods RL, et al: Metastatic adenocarcinoma of unknown primary site. A randomized study of two combination chemotherapy regimens. Eur. J. Cancer Clin. Oncol. 23: 1645-1648, 1987.
95) van der Gaast A, Verweij J, Henzen-Logmans SC, et al: Carcinoma of unknown primary: Identification of a treatable subset? Ann. Oncol. 1: 119-122, 1990.
97) DeSanto LW, Bryan Neel III H, : Squamous cell carcinoma. Metastasis to the neck from an unknown or undiscovered primary. Otolaryngol. Clin. North Am. 18: 505-513, 1985.
99) Glynne-Jones RGT, Anand AK, Young TE, et al: Metastatic carcinoma in the cervical lymph nodes from an occult primary: A conservative approach to the role of radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 18: 289-294, 1990.
101) Wax MK, Briant TDR: Surgery and postoperative radiotherapy in the management of extensive cancer of the cervical lymph nodes from an unknown primary. J. Otolaryngol. 22: 34-38, 1993.
102) McKeen E, Smith F, Haidak D, et al: Fluorouracil(F) , adriamycin(A) and mitomycin-C(M) , FAM, for adenocarcinoma of unknown origin (AUO) . Proc. of AACR and ASCO 21: 358, 1980.
103) Fiore JJ, Kelsen DP, Gralla RJ, et al: Adenocarcinoma of unknown primary origin: Treatment with vindesine and doxorubicin. Cancer Treat. Rep. 69: 591-594, 1985.
104) Bruckner HW, Crown J, McKenna A, et al: Leucovorin and 5-fluorouracil as a treatment for disseminated cancer of the pancreas and unknown primary tumors. Cancer Res. 48: 5570-5572, 1988.
106) Kelsen D, Coit D, Houston C, et al: Phase II trial of PALA, methotrexate (MTX) , fluorouraci1(FU) , and leucovorin(L) in adenocarcinoma of unknown primary site (ACUP) . Proc. of ASCO 8: 293, 1989.
109) Akerley W, Thomas A, Miller M, et al: Phase II trial of oral etoposide for carcinoma of unknown primary (CUP) . Proc. of ASCO 13: 406, 1994.
110) Jadeja J, Legha S, Burgess M, et al: Combination chemotherapy with 5-FU, adriamycin, cyclophosphamide and cis-platinum (FACP) in the treatment of adenocarcinoma of unknown primary (ACUP) and undifferentiated carcinomas (UCUP) . Proc. of ASCO 2: 237, 1983.
111) Becouarn Y, Brunet R, Barbe-Gaston C: Fluorouracil, doxorubicin, cisplatin and altretamine in the treatment of metastatic carcinoma of unknown primary. Eur. J. Cancer Clin. Oncol. 25: 861-865, 1989.
112) Ruffie P, Izzo J, Cvitkovic E, et al: Treatment of unknown primary adenocarcinoma (UPA) with fluorouracil(F) , mitomycin(M) , epirubicin(E) , and platinum(P) . Proc. of ASCO 10: 301, 1991.
114) Gill I, Guaglianone P, Grunberg SM, et al: High dose intensity of cisplatin and etoposide in adenocarcinoma of unknown primary. Anticancer Res. 11: 1231-1236, 1991.
117) Trudeau M, Thirlwell MP, Boos G, et al: Cancer of unknown primary syndrome(CUPS) : Predictive value of CA-125 in patients treated with 5-fluorouracil, doxorubicin and cisplatin(FAP) . Proc. of ASCO 12: 399, 1993.
118) Piga A, Cardarelli N, Catalano V, et al: Cancer of unknown primary site(UPT) : A collaborative study on diagnosis and treatment. Proc. of ASCO 13: 404, 1994.
119) Merrouche Y, Lasset C, Trillet-Lenoir V, et al: Phase II study of cis platinum(CDDP) and etoposide(E) in a subgroup of patients(PT) with carcinoma of unknown primary(CUP) . Proc. of ASCO 13: 401, 1994.
120) Hainthworth JD, Erland JB, Kalman LA, et al: Carcinoma of unknown primary site: Treatment with 1-hour paclitaxel, carboplatin, and extended-schedule etoposide. J. Clin. Oncol. 15: 2385-2393, 1997.
121) Shildt RA, Kennedy PS, Chen TT, et al: Management of patients with metastatic adenocarcinoma of unknown origin: A Southwest Oncology Group Study. Cancer Treat. Rep. 67: 77-79, 1983.
P.1593 掲載の参考文献
2) Schultz TF, Boshoff C, Weiss RA, et al: HIV infection and neoplasia. Lancet 348: 587-591, 1996.
4) Cooley TP: Kaposi 's sarcoma. In: HIV infection (eds. by Libman H, Witzburg RA) , Little Brown Co., Boston, USA, 1996, pp. 431-448.
5) Beral V: Epidemiology of Kaposi 's sarcoma in cancer surveys. In: Cancer, HIV and AIDS (eds. by Beral V, Jaffe HW, Weis R) , Vol. 10, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 1991, pp. 5-22.
8) 小池盛雄, 倉田 毅, 森 茂郎: 剖検例からみた日本のエイズ(厚生省科学研究費エイズ対策推進事業, HIV感染者発症予防治療に関する研究班, 文部省エイズ制圧のための基礎研究班共同研究) . 1994, pp. 123-126.
9) 森山佐知子, 猪狩 豪, 比島恒和・他: AIDS剖検例におけるKaposi肉腫の検討. 厚生省平成8年度HIV感染者発症予防治療に関する研究班研究報告書. 1997, pp. 303-308.
11) Northfelt, DW: Kaposi 's sarcoma: Epidemiology and clinical characteristics. In: The AIDS Knowledge Base, 2nd Edition (eds. by Cohen PT, Sande MA, Volberding PA) , Little Brown and Company, Boston/New York/Toronto/London, 1994, pp. 7. 1-1-7. 1-6.
16) Huang Y-Q, Huang Y, Li JJ, et al: Human herpes virus-like DNA sequence in various forms of Kaposi 's sarcoma. Lancet 345: 759-761, 1995.
17) Boshoff C, Whitby D, Hatziannou T, et al: Kaposi 's sarcome associated herpes virus in HIV negative Kaposi 's sarcoma. Lancet 345: 1043-1044, 1995.
21) Simpson GR, Sdultz TF, Whitby D, et al: Prevalence of Kaposi 's sarcoma associated herpes virus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen. Lancet 348: 1133-1138, 1996.
23) Rady PL, Yen A, Rollefson JL, et al: Herpes Virus-like DNA sequences in non Kaposis sarcoma. Lancet 345: 1339-1342, 1995.
25) Kaplan LD, Northfelt DW: Malignancies associated with AIDS. In: The Management of AIDS (eds. by Sarde MA, Volberding PA) . WB Saunders Co., Philadelphia, USA, 1995, pp. 555-590.
26) Knowles DM, Inghirami G, Ubraaco A, et al: Molecular genetic analysis of three AIDS-associated neoplasms of uncertain lineage demonstrates their B-cell derivative and the possible pathogenetic role of EBV. Blood 73: 792-799, 1989.
30) Green I, Espiritu E, Ladanyi M, et al: Primary lymphomatous effusion in AIDS: a morphological immunophenotypic, and molecular study. Mod. Pathol. 8: 39-45, 1995.
33) Harris NL, Jaffe ES, Stein H, et al: A revised European American classification of lymphoid neoplasmas: a proposal from the International Lymphoma Study Group. Blood 84: 1361-1392, 1994.
36) Soulier J, Grollet L, Oksenhendler E, et al: Kaposi 's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman 's disease. Blood 86: 1276-1280, 1995.
37) Yoshizaki K, Matsuda T, Nishimoto N, et al: Pathogenetic significance of interleukin-6(IL 6/BSF-2) in Castleman 's disease. Blood 74: 1360-1367, 1989.
39) Ng VL, Komanduri KV, Luce JA, et al: Clinical and laboratory features of HIV-associated body cavity based lymphomas. Blood 86(suppl. 1) : 379 a (abstract no. 1506) , 1995.
40) Volberding PA, Kusicke P, Feigal DW: Effect of chemotherapy for HIV associated Kaposi 's sarcoma on longterm survival. Proceeding of the American Society of Clinical Oncology, San Francisco, 1989, 11.
41) Kaplan LD, Kahn J: Therapy for HIV-associated Kaposi 's sarcoma. In: The AIDS Knowledge Base, 2nd Edition (eds. by Cohen PT, Sande MA, Volberding PA) . Little Brown and Company, Boston/New York/Toronto/London, 1994, pp. 7. 3-1-7. 3-11.
42) Schultz TF, Boshoff CH, Weiss RA: HIV infection and neoplasma. Lancet 348: 587-591, 1996.
44) Newman SB: Treatment of epidemic Kaposi 's Sarcoma(KS) with intralegionl vinblastine infusion(IL-VLB) . Proceedings of the American Society of Clinical Oncology, New Orleans, 1988, 19.
53) Knowles DM, Chamulak G, Subar M, et al: Clinicopathological, immunophenotypic, and molecular genetic analysis of AIDS-associated lymphoid neoplasia: clinical and biologic implications. Pathol. Annu. 23: 33-67, 1988.
55) Ziegler JL, Beckstead JA, Volberding PA, et al: Non-Hodgkin 's lymphoma in 90 homosexual men: relation to generalized lymphadenopathy and the acquired immunodeficiency syndrome. N. Engl. J. Med. 311: 565-570, 1985.
56) Kaplan LD: Lymphomas: Clinical characteristics and diagnosis. In: The AIDS Knowledge Base, 2nd Edition (eds. by Cohen PT, Sande MA, Volberding PA) , Little Brown and Company, Boston/New York/Toronto/London, 1994, pp. 7. 5-1-7. 5-5.
61) Pfister H: Relationship of papilloma viruses to anogenital cancer. Obstet. Gynecol. Clin. North. Am. 14: 349-361, 1987.
63) Schrager LK, Friedland GH, Maude D, et al: Cervical and vaginal squamatous cell abnormalities in women infected with human immunodeficiency virus. J. Acquir. Immune. Defic. Syndr. 2: 570-575, 1989.
64) Sun X-W, Kuhn L, Ellerbrook TV, et al: Human papillomavirus infection in woman infected with the human immuno deficiency virus. N. Engl. J. Med. 337: 1343-1349, 1997.
65) Shafer A, Friedmann W, Mielke M: The increased frequency of cervical dysplasia-neoplasia in women infected with the human immunodeficiency virus is related to the degree of immunosuppression. Am. J. Obstet. Gynecol. 164: 593-599, 1991.
70) Northfeld DN: Anal Neoplasia. In: The AIDS Knowledge Base, 2nd Edition(eds. by Cohen PT, Sande MA, Volberding PA) . Little Brown and Company, Boston/New York/Toronto/London, 1994, pp. 7. 8-1-7. 8-4.
72) Gal AA, Saul SH, Stoler MH: In situ hybridization analysis of human papillomavirus in anal squamous cell carcinoma. Mod. Pathol. 2: 439-443, 1989.
75) Hesool NA, Katz MH, Liu JK, et al: Increased incidence of Hodgkin disease in homosexual men with HIV infection. Ann. Intern. Med. 117: 309-311, 1992.
P.1609 掲載の参考文献
1) Eckhardt SJ: Paraneoplastic syndromes. Cancer Surveys Palliative Medicine: Problem areas in pain and symptom management. 21: 197-209, 1994.
3) Graaf JH, Tamminga RYJ, Kamps WA: Paraneoplastic manifestations in children. Eur. J. Pediatr. 153: 784-791, 1994.
4) Darnel RB: Onconeural antigens and the paraneoplastic neurologic disorders: At the intersection of cancer, immunity, and the brain. Proc. Natl. Acad. Sci. USA 93: 4529-4536, 1996.
6) Drlick M, Bianchi G, Boglium G, et al: Antibodies of the anti-Yo and anti-Ri type in the absence of "paraneoplastic" neurological syndromes: along-term survey of ovarian cancer patients. J. Neurol 244: 85-89, 1997.
12) Harrack JE, Kimmel DW, O'Neil BP, et al: Paraneoplastic cerebellar degeneration: A clinical comparison of patients with and without Purkinje cell cytoplasmic antibodies. Mayo Clin. Proc. 65: 1424-1431, 1990.
13) Peterson K, Rosenblum MK, Kotanides H, et al: Paraneoplastic cerebellar degeneration. 1. A clinical analysis of 55 anti-Yo antibody positive patients. Neurology 42: 1931-1937, 1992.
14) Marchioli CC, Graziano SL: Paraneoplastic syndromes associated with small cell lung cancer. Chest Surgery Clin North Am. 7: 65-80, 1997.
17) Anderson NE, Budde-Steffen C, Rosenblum MK, et al: Opsoclonus, myoclonus, ataxia and encephalopathy in adults with cancer: A distinct paraneoplastic syndrome. Medicine 67: 100-109, 1986.
26) Jean WC, Dalmau J, Ho A, et al: Analysis of the IgG subclass distribution and inflammatory infiltrates in patients with anti-H and the paraneoplastic neurologic disorders: At the intersection of cancer immunity, and the brain. Proc. Natl. Acad. Sci. USA 93: 529-4536, 1996.
27) 広瀬源二郎: 辺縁系脳炎. 臨床神経化学 15: 912-913, 1997.
29) Posner JB: Paraneoplastic syndrome. Neurol. Clin. 9: 919-937, 1991.
37) O'neil JH, Murray NMF, Newsom-Davis J: The Lambert-Eaton myasthenic syndrome. Brain 111: 577-596, 1988.
41) Takamori M, Takahashi M, Yasukawa Y, et al: Antibodies to recombinant synaptotagmin and calcium channel subtyper in Lambert-Eaton myasthenic syndrome. J. Neurol. Sci. 133: 95-101, 1995.
43) 井村 裕夫, 清野 裕: 内分泌・代謝学第4版, 医学書院, 東京, 1997, pp. 397-407.
45) Imura H, Matsukura S, Yamamoto H, et al: Studies on ectopic ACTH-producing tumors. II Clinical and biochemical features of 30 cases. Cancer 35: 1430-1437, 1975.
47) Oldfield EH, Doppman JL, Nieman LK et al: Petrosal sinus sampling with and without corticotropin-releasing hormone for the differntial diagnosis of cushing 's syndrome. N. Engl. J. Med. 325: 897-905, 1991.
58) Sato K, Fujii Y, Kakiuchi T, et al: Paraneoplastic syndrome of hypercalcemia and hormone related protein, interleukin 1α, and granulocyto colony stimulating factor. Cancer Res. 49: 4740-4746, 1989.
60) Kimura S, Sato Y, Matsubara H, et al: Aretrospective evaluation of the medical treatment of malignancyassociated hypercalcemia. JPn. J. Cancer Res. 77: 85-91, 1986.
61) Thiebaud D, Jacquet F, Bruckhardt P: Fast and effective treatment of malignant hypercalcemia-combination of suppositories of calcitonin and a single infusion of 3-amino 1-hydroxypropylidene-1-bisphosphonate. Arch. Intern. Med. 150: 2125-2128, 1990.
64) Kondo Y, Mizumoto Y, Katayama S, et al: Inappropriate secretion of antidiuretic hormone in nude mice bearing a human bronchogenic oat cell carcinoma. Cancer Res. 41: 1545-1548, 1981.
66) DeTroyer A: Demeclocycline treatment for syndrome of inappropriate antidiuretic hormone secretion. JAMA 237: 2723-2726, 1977.
71) Gross AJ, Steinberg SM, Reilly JG, et al: A trial natriuretic factor and arginine vasopressin production in tumor cell lines from patients with lung cancer and their relationship to serum sodium. Cancer Res. 53: 67-74, 1993.
72) Blackman MR, Weintraub BD, Rosen SW, et al: Human placental and pituitary glycoprotein hormones and their subunits as tumor markers: aquantative assessment. J. Natl. Cancer Inst. 65: 81-93, 1980.
75) McArthy JH, Kahn CR, Roth J, et al: Two cases of carcinoma of the lung characterized by a bone marrow agar culture pattern resembling acute myeloid leukemia. Blood 54: 530-533, 1979.
78) Tracy KJ, Wei H, Manogue KR: Cachectic/tumour necrosis factor induces cachexia, anemia and inflammation. J. Exp. Med. 167: 1211-1227, 1988.
81) Sytokowski AJ, Richie Jp, Bicknell KA: New human renal carcinoma cell line established from a patient with erythrocytosis. Cancer Res. 43: 1414-1419, 1983.
82) Ricckles FR, Edwards RL: Activation of blood coagulation in cancer. Trousseau 's syndrome revised. Blood 62: 14-31, 1983.
83) Silverberg JM, Gordon S, Zucker S: Identification of tissue factor in two pancreatic cell lines. Cancer Res. 49: 5443-5447, 1989.
85) Kruzrock R, Cohen PR: Cutaneous paraneoplastic syndromes in solid tumors. Am. J. Med. 99: 662-671, 1995.
86) Kruzrock R, Cohen PR: Mucocutaneous paraneoplastic manifestations of hematologic malignancies. Am. J. Med. 99: 207-216, 1995.
88) Schneerson JM: Digital clubbing and hypertrophic osteoarthropathy: The underlying mechanisms. Br. J. Dis. Chest 75: 113-131, 1981.
91) Cohen PR: Paraneoplastic dermatopathology: Cutaneous paraneoplastic syndromes. Adv. Dermatol. 11: 215-252, 1996.
P.1618 掲載の参考文献
1) Negrini D, Pistolesi M, Miniati M, et al: Regional protein absorption rates from the pleural cavity in dogs. J. Appl. Physiol. 58: 20622067, 1985.
2) Negrini D, Ballard ST, Benoit JN: Contribution of lymphatic myogenic activity and of respiratory movements to pleural lymph flow. J. Appl. Physiol. 76: 2267-2274, 1994.
3) Hausheer FH, Yarbro JW: Diagnosis and treatment of malignant pleural effusion. Semin. Oncol. 12: 54-75, 1985.
4) 二宮和子, 松原義人, 青木 稔・他: 胸膜炎238例の臨床的検討. 日胸 43: 39-45, 1984.
5) 水島 豊, 星野 清, 川崎 聰・他: 胸水穿刺施行115例の臨床的検討. 日胸 49: 135-140, 1990.
6) Lueallen EC, Carr DT: Pleural effusion: Astatistical study of 436 patients. N. Engl. J. Med. 252: 79-83, 1955.
12) Sugiyama S, Ando Y, Minami H, et al: Prognostic value of pleural effusion in patients with non-small cell lung cancer. Clin. Cancer Res. 3: 47-50, 1997.
14) Kondo H, Asamura H, Suemasu K, et al: Prognostic significance of pleural lavage cytology immediately after thoracotomy in patients with Iung cancer. J, Thorac. Cardiovasc. Surg. 106: 1092-1097, 1993.
15) Ruckdeschel JC: Management of malignant pleural effusion: an overview. Semin. Oncol. 15(suppl. B) : 24-28, 1988.
23) Rodriguez-Panadero F, Lopez MJ: Low glucose and pH levels in malignant pleural effusions: diagnostic significance and prognostic value in respect to pleurodesis. Am. Rev. Respir. Dis. 139: 663-667, 1989.
25) Martinez-Vea A, Gatell JM, Segura F, et al: Diagnostic value of tumoral markers in serous effusions: carcinoembryonic antigen, alpha 1-acid glycoprotein, alpha-fetoprotein, phosphohexose isomerase and beta 2-microglobulin. Cancer 50: 1783-1788, 1982.
26) Satoh H, Sumi M, Yagyu H, et al: Clinical evaluation of CYFRA 21-1 in malignant pleural fluids. Oncology 52: 211-214, 1995.
35) 宮沢直人, 横井香平, 神谷紀輝・他: 癌性胸膜炎. 日本臨牀(別冊 呼吸器症候群) : 762-765, 1994.
36) 原 信之, 萩本直樹, 中西洋一: 癌性胸膜炎, 心膜炎の治療. 医学のあゆみ 180: 331-334, 1997.
37) Moffett MJ, Ruckdeschel JC: Bleomycin and tetracycline in malignant pleural effusions: A review. Semin. Oncol. 19: 59-63, 1992.
45) McFadden PM, Jones JW: Tube thoracostomy: anatomical considerations, overview of complications, and a proposed technique to avoid complications. Military Med. 150: 681-685, 1985.
47) Firmin RK, Welch JD: Insertion of a chest drain. Ilospital Update 6: 481-486, 1980.
52) Sahn SA: Pleural effusion in lung cancer. Clin. Chest Med. 3: 443-452, 1982.
57) Greewald DW, Phillips C, Bennett JM: Management of malignant pleural effusion. J. Surg. Oncol. 10: 361-368, 1978.
63) Rodriguez-Panadero F, Antony VB: Pleurodesis: state of the art. Eur. Respir. J. 10: 1648-1654, 1997.
72) Bjorkman S, Elisson LO, Gabrielson J: Pharmacokinetics of quinacrine after intrapleural instillation in rabbits and man. J. Pharm. Pharmacol. 41: 160-163, 1989.
74) Albert DS, Chen HS, Mayersohn M, et al: Bleomycin pharmacokinetics in man. Cancer Chemother. Pharmacol. 2: 127-132, 1979.
76) Bleomycin sulfate. In: AHFS Drug Information 92 (ed by McEvoy GK) . American Society of Hospital Pharmacists, Bethesda, Maryland, 1992, pp. 488-490.
77) 山口恵理子, 永井厚志, 坂本匡一・他: ブレオマイシンの胸腔内投与における胸膜の形態変化. 癌と化学療法 18: 971- 975, 1991.
78) Sitton DW(ed) : Drug Topics Red Book 1992. Montvale, N 'ew Jersey, Medical Economics Data;1992.
79) Walker-Renard PB, Vaughan LM, Sahn SA: Chemical pleurodesis for malignant pleural effusions. Ann. Intern. Med. 120: 56-64, 1994.
80) Kefford RF, Woods RL, Fox RM, et al: Intracavitary adriamycin, nitrogen mustard and tetracycline in the control of malignant effusions: arandomized study. Med. J. Aust. 2: 447-448, 1980.
81) 植田保子, 広田正毅, 朝長昭光・他: Adriamycinを用いた癌性胸膜炎の治療. 癌の臨床 28: 789-793, 1982.
83) Luh KT, Yang PC, Kuo SH, et al: Comparison of OK-432 and mitomycin C pleurodesis for malignant pleural effusion caused by lung cancer: A randomized trial. Cancer 69: 674-679, 1992.
86) Antini E, Cavazzini G, Pasquini E, et al: Treatment of primary or metastatic pleural effusion with intracavitary cytosine arabinoside and cisplatin. Acta Oncol. 33: 191-194, 1994.
89) Ostrowsky MJ, Priestman TJ, Houstman RF, et al: A randomized trial of intracavitary bleomycin and Co rynebacte rium parvum in the control of malignant pleural effusions. Radiother. Oncol. 14: 19-26, 1989.
90) 長尾啓一, 滝沢弘隆, 椙田 隆・他: OK-432による癌性胸膜炎の治療. チューブドレナージ法について. 癌と化学療法 6: 1161-1166, 1979.
91) 長尾啓一: 癌性胸膜炎の治療に関する研究. 千葉医誌 58: 345-353, 1982.
92) 浦田淳夫, 西村 穣, 太田和雄: OK-432による癌性胸膜炎の治療. 癌と化学療法 13: 1497-1503, 1983.
93) 長尾啓一: 癌性胸膜炎に対するOK-432胸腔内投与. Ther. Res. 10: 3857-3864, 1989.
94) Rosso R, Rimoldi R, Salvati F, et al: Intrapleural natural beta interferon in the treatment of malignant pleural effusions. Oncology 45: 253-256, 1988.
96) Monti G, Jaurand MC, Monnet I, et al: Intrapleural production of interleukin 6 during mesothelioma and its modulation by γ-interferon treatment. Cancer Res. 54: 4419-4423, 1994.
101) 一瀬幸人, 原 信之, 矢野篤次郎・他: 開胸により発見された癌性胸膜炎および胸腔内再発リスク症例に対する術中胸腔内hypotonic cisplatin treatment. 肺癌 33: 233-238, 1993.
102) 厚生省がん研究助成金指定研究「固形がんの集学的治療の研究」班編: 非小細胞肺癌による癌性胸膜炎に対する「ブレオマイシン局所癒着療法」と「OK-432局所癒着療法」と「シスプラチン, エトポシド併用局所化学療法」との Randomized Phase II試験. JCOG集学的治療プロトコール集(第10集) , 1997, pp. 1-38.
P.1629 掲載の参考文献
1) McAllister HA, Fenoglio JJ: Tumors of the cardiovascular system-Tumors of the heart and pericardium. In: Atlas of tumor pathology (ed. by Hartmann WH) , Armed Forces Institute of Pathology, Washington, 1978, pp. 111-119.
2) Mukai K, Shinkai T, Tominaga K, et al: Incidence of secondary tumors of the heart and pericardium: a l0-year experience of one institution. JPn. J. Clin. Oncol. 18: 195-201, 1988.
6) Vaikus PT, Herrmann HC, LeWinter MM: Treatment of malignant pericardial effusion. JAMA 272: 59-64, 1994.
16) 新海 哲: 胸水, 心嚢水. 最新内科学体系. 第80巻臨床腫瘍学(関連領域疾患4) (井村裕夫, 尾形悦朗, 高久史麿, 垂井清一郎編, 阿部 薫専門編) . 中山書店, 東京, 1995, pp. 368-373.
17) Hankin Jp, Satterfield JR, Aisner J, et al: Pericardial window for malignant pericardial effusion. Ann. Thorac. Surg. 30: 465-471, 1980.
18) Shinkai T, Tominaga K, Saijo N, et al: The incidence of cardiac metastasis in primary lung cancer and the management of malignant pericardial effusion. JPn. J. Clin. Oncol. 12: 23-32, 1982.
P.1634 掲載の参考文献
1) 近田千尋: 癌の細胞診と癌治療"胸腹水", 癌と化学療法 9: 1716-1720, 1982.
2) Lacy JH, Wieman TJ, Shively EH: Management of Malignant Ascites. Surg. Gynecol. Obstet. 159: 397-412, 1984.
3) 曽和融生, 加藤保之: 癌性腹膜炎に対する対症療法の実際2) 腹水の対策. 消化器外科 14: 1503-1507, 1991.
4) 山本政勝: 癌性腹膜炎. 消化器病学(亀田治男, 武藤輝一編) 第2版, 朝倉書店, 東京, 1981, pp. 655-663.
5) 佐々木大輔, 大川正臣, 坂田 優・他: 肝癌, 転移性肝癌および肝硬変の腹水に対するSoldactone (Potassium car-renoate) の使用経験. 新薬と臨床 31: 27-35, 1981.
6) 横山正和: 腹膜癌. 化学療法の領域 2: 1757-1766, 1986.
7) 小貫 誠, 波多野剛之, 児玉秀文・他: 肝硬変難治腹水症および癌性腹膜炎における濃縮腹水還流装置での治療. 現代医療 11: 1379-1384, 1979.
8) 小山善之, 斉藤達雄: 固形がん化学療法の臨床効果判定基準. 日癌治療会誌 21: 929-942, 1986.
9) 萩原明於, 高橋俊雄, 李 方行・他: 活性炭吸着マイトマイシンC(MMC-CH) による癌性胸腹膜炎の治療-臨床応用の結果について-. 日癌治療会誌 20: 2144-2153, 1985.
10) 清水敬生: 卵巣癌の治療-腹腔内化学療法. KARKINOS 7: 1027-1033, 1994.
13) 小倉 剛, 曽根三郎, 仁井昌彦・他: 転移癌に対する治療戦略-癌性胸, 腹膜炎に対する治療. Oncologia 20(5) : 48- 56, 1987.
14) 坂田正毅, 鳥巣要道: 癌性腹膜炎の免疫療法. 消化器外科 6: 1195-1203, 1983.
15) 涌井 昭, 斉藤達雄, 中尾 功・他: 消化器癌の癌性腹水に対するRecombinant Interferon-β (GKT-β) の腹腔内投与の効果. BIOTHERAPY 2: 339-347, 1988.
16) 漆崎一朗, 新津洋司郎, 高後 裕: 抗腫瘍性サイトカイン. Oncologia 20: 105-121, 1987.
17) Gilly FN, Carry PY, Sayag AC, et al.: Regional Chemotherapy (with MitomycinC) and IntraoperativeHyperthermia for Digestive Cancers with Peritoneal Carcinomatosis. Hepatogastroenterology 41: 124-129, 1994.
18) 沖永功太, 安達実樹, 並木一信: 癌性腹膜炎に対する対症療法の実際-イレウスの対策. 消化器外科 14: 1497-1501, 1991.
20) Loggie BW, Perini M, Fleming RA. et al.: Treatment and prevention of malignant ascites associated with disseminated intraperitoneal malignancies by aggressive combined-modality therapy. Am. Surg. 63: 2, 137-143, 1997.
21) Yamaguchi Y, Satoh Y, Miyahara E, et al.: Locoregional immunotherapy of malignant ascites by intraperitoneal administration of OK-432 plus IL-2 in gastric cancer patients. Anticancer Res. 15: 5B, 2201-2206, 1995.
P.1643 掲載の参考文献
1) Viadana E, Erros IDJ, Pickren WJ: Cascade spread of blood-born metastases in solid and nonsolid cancers of humans. Pulmonary metastasis (ed. by Weiss L, Gilbert HA) , Martinus Nijhoff Medical Division, Hague-Boston, London, 1978, pp. 142-167.
2) 末舛恵一, 米山武志, 成毛詔夫・他: がん転移の基礎と臨床. 癌と化学療法 14: 561-566, 1987.
4) 森 亘, 足立山夫, 岡辺治男・他: 悪性腫瘍剖検例755例の解析-その転移に関する統計的研究-. 癌の臨床 9: 351-374, 1963.
6) Lore JM, Madden JL, Gerold FP: Pre-existing porta caval shunts. Cancer 11: 24-27, 1958.
7) Heitmiller RF, Marasco WJ, Hruban RH, et al: Endobronchial metastasis. J. Thorac. Cardiovasc. Surg. 106: 537-542, 1993.
16) Einhorn LH, Williams SD, Donohue JO, et al: Cancer of the testis. Cancer; Principles & Practices of Oncology (ed. by Devita VT, et al) , (2 nd. ed.) , J. B. Lippincott, Philadelphia, 1985, pp. 979-1011.
17) Shimosato Y, Baba K, Oboshi S, et al: Pathological studies on pulmonary cancer treated with bronchial artery infusion of mitomycin C. Jpn. J. Cancer Clin. 14: 945-957, 1968.
18) Thomford NR, Woolner LB, Clagett OT, et al: The surgical treatment of metastatic tumors in the lungs. J. Thorac. Cardiovasc. Surg. 49: 357-363, 1965.
19) 近藤晴彦: 転移性肺癌の外科治療. 日臨外医会誌 58: 495-501, 1997.
31) Aberg T, Malmberg KA, Nilsson B, et al: The effect of metastatectomy: Fact or fiction? Ann. Thorac. Surg. 30: 378-384, 1980.
32) 原 勲, 郷司和男, 荒川創一・他: 腎癌とサイトカイン. Biotherapy 11: 893-899, 1997.
P.1653 掲載の参考文献
2) Couinaud C, Le Foie: Etudes Antomiques et Chirurgicales. Masson, Paris, 1957.
3) Makuuchi M, Hasegawa H, Yamasaki S: Ultrasonically guided subsegmentectomy. Surg. Gynecol. Obstet. 161: 346, 1985.
4) Pickren JW, Tsukada Y, Lane WW: Analysis and autopsy data. In: Liver metastasis (eds. by Weiss L, Gilbert HA) . Hall Medical Publishers, Boston, 1982.
5) 森岡恭彦, 長尾 桓: 転移性肝腫瘍. 最新内科学大系第50巻, 中山書店, 東京, 1991, pp. 251-274.
6) 草野満夫・他: 転移性肝癌の治療. 日消外会誌 57: 1595, 1987.
14) Jaffe BM, Donegan W, Watson F, et al: Factors influencing survival in patients with untreated hepatic metastases. Surg. Gynecol. Obstet. 127: 1-11, 1968.
16) Nielsen J, Balslev I, Jensen H: Carcinoma of the colon with liver metastases. Operative indications and prognosis. Acta Chir. Scand. 137: 463-465, 1971.
17) Wood CB, Gillis CR, Blumgart LH: A retrospective study of the natural history of patients with liver metastases from colorectal cancer. Clin. Oncol. 2: 285-288, 1976.
25) Aberg T, Malmber KA, Nilsson B, et al: The effect of metastasectomy: fact or fiction? Ann. Thorac. Surg. 30: 378-384, 1980.
28) Thomford NR, Woolner LB, Clagett OT: The surgical treatment of metastatic tumors in the lungs. J. Thorac. Cardiovasc. Surg. 49: 357-363, 1965.
30) Scheele J, Stangl R, Altendorf-Hoffmann A, et al: Indicators of prognosis after hepatic resection for colorectal secondaries. Surgery 110113-29, 1991.
39) Morrow CE, Grage TB, Sutherland DER, et al: Hepatic resection for secondary neoplasms. Surgery 92: 610-614, 1982.
40) Rajpal S, Dasmahapatra KS, Ledesma E, et al: Extensive resections of isolated metastases from carcinoma of the colon and rectum. Surg. Gynecol. Obstet. 155: 813-816, 1982.
42) Thoma-de la Vega JE, Donahue EJ, Doolas A, et al: A ten year experience with hepatic resection. Surg. Gynecol. Obstet. 159: 223-228, 1984.
43) Nims TA: Resection of the liver for metastatic cancer. Surg. Gynecol. Obstet. 158: 46-48, 1984.
50) Bozzetti F, Bignami P, Morabito A, et al: Patterns of failure following surgical resection of colorectal cancer liver metastases. Rationale for multimodal approach. Ann. Surg. 205: 264-270, 1986.
52) Butler J, Attiyeh FF, Daly JM: Hepatic resection for metastases of the colon and rectum. Surg. Gynecol. Obstet. 162: 109-113, 1986.
53) Iwatsuki S, Esquivel CO, Gordon RD, et al: Liver resection for. metastatic colorectal cancer. Surgery 100: 804-809, 1986.
56) Cobourn CS, Makowka L, Langer B, et al : Examination of patient selection and outcome for hepatic resection for metastatic disease. Surg. Gynecol. Obstet. 165: 239-246, 1987.
58) Sesto ME, Vogt DP, Hermann RE: Hepatic resection in 128 patients: a 24-year experience. Surgery 102: 846-851, 1987.
60) Registry of hepatic metastases. Resection of the liver for colorectal carcinoma metastases: a multi-institutional study of indication for resection. Surgery 103: 278-288, 1988.
62) Schlag P, Hohenberger P, Herfarth Ch: Resection of liver metastases in colorectal cancer-competitive analysis of treatment results in synchronous versus metachronous metastases. Eur. J. Surg. Oncol. 16: 360-365, 1990.
67) Gayowski TJ, Iwatsuki S, Madariage JR, et al: Experience in hepatic resection for metastatic colorectal cancer: analysis of clinical and pathologic risk factors. Surgery 116: 703-711, 1994.
72) Wolf RF, Goodnight JE, Krag DE, et al: Results of resection and proposed guidelines for patient selection in instances of non-colorectal hepatic metastases. Surg. Gynecol. Obstet. 173: 454-60, 1991.
74) Makuuchi M, et al: Preoperative portal embolization to increase safety of major hepatectomy for hilar bile duct carcinoma. A preliminary report. Surgery 107: 521-527, 1990.
75) Kawasaki S, Makuuchi M, Kakazu T, et al: Resection for multiple metastatic liver tumors aftcr portal embolization. 151674, 1994.
76) Hughes KS, Simon R, Songhorabodi S, et al: Resection of the liver for colorectal carcinoma metastases: a multi-institutional study of patterns of recurrence. Surgery 100: 278-284, 1986.
78) Lange JF, Leese T, Castaing D, et al: Repeat hepatectomy for recurrent malignant tumors of the liver. Surg. Gynecol. Obstet. 169: 119-126, 1989.
80) Huguet C, Bona S, Nordlinger B, et al: Repeat hepatic resection for primary and metastatic carcinoma of the liver. Surg. Gynecol. Obstet. 171: 398-402, 1990.
83) Guillat C, Ducerf C, Partensky C, et al: Repeated hepatic resections for colorectal metastases. Eur. J. Surg. Oncol. 19: 443-447, 1993.
87) Fernandez-Trigo V, Shamsa F, Sugarbaker PH: Repeat Hepatic Metastasis Registry. Repeat liver resections from colorectal metastasis. Surgery 117: 296-304, 1995.
88) Quyen DC, Vezeridis MP, Avradopulos KA, et al: Repeat hepatic resection for recurrent colorectal cancer. World J. Surg. 21: 292-296, 1997.
90) Craig JR, Peters RL, Edmondson HA: Metastatic tumors. In: Tumors of the liver and intrahepatic bile ducts. Armed Forces Institute of Pathology, Washington D. C. 1989, p. 256.
91) 高安賢一: 転移性肝癌. 肝臓の画像診断-細小肝癌の発見から治療まで(高安賢一著) . 文光堂, 東京, 1991, p. 262.
P.1665 掲載の参考文献
1) 日本整形外科学会骨軟部腫瘍委員会: 全国骨腫瘍患者登録一覧表(平成7年度) . 国立がんセンタ-, 1995.
2) Harrington KD: Orthopaedic Management of Metastatic Bone Disease. The CV Mosby, St. Louis, Washington, DC, Toronto, 1988.
3) 福間久俊, 館崎新一郎: 骨腫瘍の鑑別診断. 整形外科診断学(辻 陽雄, 高橋栄明編) , 第2版, 金原出版, 東京, 1988, pp. 631-650.
4) 明神美弥子: 転移性脊椎腫瘍の放射線治療におけるMRI診断の意義. 厚生省がん研究助成金による研究報告集(平成7年度) , 7-18尾形悦郎班. 1995, pp. 339-342.
6) 志水克時: 転移性腫瘍. 整形外科手術(1) (富田勝郎編) , 第1版, 中山書店, 東京, 1995, pp. 178-182.
7) Sonoo H, Shimozuma K, Kurebayashi J, et al: Systemic therapy, pain relief and quality of life of breast cancer patients with bone metastasis. Gan To Kagaku Ryoho 22(suppl. 1) : 10-15, 1995.
8) Shiba E, Kobayashi T, Takeda T, et al: Acase of advanced breast cancer with multiple organ metastases successfully treated by tamoxifen. Gan To Kagaku Ryoho 19(13) : 2255-2258, 1992.
9) Nishioka A, Ogawa Y, Hamada N, et al: A case report of bone metastasis diagnosed by MRI and effectively treated with UFT after breast concerving therapy for breast cancer. Gan To Kagaku Ryoho 19(13) : 2251-2254, 1992.
12) Fujita K, Mathushima H, Nakano M, et al: Ifosfamide in combined hormonochemotherapy on prostate cancer. Gan To Kagaku Ryoho 21(2) : 227-230, 1994.
13) Harada Y, Arima S, Futami K, et al: A case of remarkable response of colon cancer with multiple liver and bone metastasis. Gan To Kagaku Ryoho 22(1) : 123-127, 1995.
14) Kobayashi T, Sasaki T, Ibuka T, et al: Sequential MTX and 5 FU therapy of gastric cancer with systemic bone metastasis and disseminated intravascular coagulation. Gan To Kagaku Ryoho 19(1) : 69-74, 1992.
15) Tanaka S, Morikawa Y: Complete remission of bone metastasis of bladder cancer treated by cisplatin-etoposide therapy. Gan To Kagaku Ryoho 18(6) : 1039-1041, 1991.
16) 山脇慎也, 小林昌幸, 井須和男・他: がんの骨転移の治療. Mebio 4(1) : 11-17, 1987.
18) Honda K, Simizu C: Long term paincontrol in terminal care with homehospice care. Gan To Kagaku Ryoho 21(Suppl. 4) : 489-492, 1994.
20) 佐々木和朗, 笠井祐子: 硬膜外ブロック使用による経口モルヒネ鎮痛法とQOLダイヤグラムによる評価. 在宅癌治療 2: 45-51, 1991.
21) 笠井祐子, 佐々木和朗: 癌疼痛治療とQOLダイヤグラムによる評価法. 癌治療と宿主 4(1) : 86-93, 1992.
22) 笠井祐子: 癌患者のQuality of life(QOL) の新しい評価法. 北海道医誌 69(2) : 282-292, 1994.
23) 大川智彦, 赤座英之, 安達 勇・他: 日本癌治療学会 骨転移治療効果判定基準(案) . 日癌治療会誌 32(6) : 883- 888, 1997.
P.1673 掲載の参考文献
1) 脳腫瘍全国統計委員会: 脳腫瘍全国集計調査報告9巻(1969-1990) . 1996.
2) Galicich JH, Arbit E: Metastatic brain tumors. Nurological surgery(ed by Youmans JR) , WB Saunders, London, Tokyo, 1990, pp. 3204-3222.
3) Takakura K, Sano K, Hojo S, et al: Metastatic tumors of the central nervous system. Igakushoin, Tokyo-New York, 1982.
4) Posner JB, Chernik NL: Intracranial metastases from systemic cancer. Adv. Neurol. 19: 575-587, 1978.
5) Posner JB: Management of brain metastasis. Rev. Neurol. (Paris) 148: 477-487, 1992.
9) 生塩之敬: 転移性脳腫瘍. 図説癌シリーズ, 脳腫瘍(末舛惠一, 高倉公朋編) , メジカルビュー社, 東京, 1987, pp. 143- 151.
10) Dale AJD, Okazaki H: Meningeal carcinomatosis: Clinical manifestations. Arch. Neurol. 30: 138-143, 1974.
11) Mandell L, Hilaris B, Sullivan M, et al: The treatment of single brain metastasis from non-oat cell lung carcinoma. Cancer 58: 641-649, 1986.
12) 松谷雅生: 転移性脳腫瘍. 脳神経外科学(太田富雄編) , 第7版, 金芳堂, 1996, pp. 671-680.
13) 松谷雅生: New Lecture. 第2版, 篠原出版, 東京, 1996, pp. 333-347.
17) Tsuchiya K, Inaoka S, Mizutani Y, et al: Fast fluid-attenuated interversion-recovery MR of intracranial infections. AJNR 18: 909-913, 1997.
18) 遠藤啓吾: がんの核医学診断. 核医学 32: 1125-1130, 1995.
19) 野村和弘, 渡辺 卓: M因子の解析-転移性脳腫瘍とCT診断. 肺癌の画像診断(鈴木 明, 河野通雄, 江口研二編) , 日本肺癌学会, 東京, 1988, pp. 109-115.
20) 松谷雅生, 河野 正, 長島 正・他: 肺癌脳転移の手術放射線治療. 日癌治療会誌 18: 1979-1986, 1983.
24) 中村 治, 松谷雅生, 長島 正・他: 乳癌脳転移の治療. 癌の臨床 35: 979-982, 1989.
25) 高橋 昭, 山本正彦, 祖父江逸郎: 髄膜癌腫症. 臨床成人病 10: 149-158, 1980.
26) 山下純宏, 大塚信一, 山崎俊樹・他: 肺癌脳転移116例の臨床的検討-手術および放射線治療の相対的役割. 日癌治療会誌 18: 1124-1134, 1983.
28) White K, Fleming TR, Laws ER Jr: Single metastasis to the brain. Surgical treatment in 122 consecutive patients. Mayo Clin. Proc. 56: 424-428, 1981.
32) 浅井昭雄, 松谷雅生, 高倉公朋: 脳腫瘍放射線治療後の亜急性障害としての脳萎縮と痴呆. 癌の臨床 33: 753-761, 1987.
34) Joseph J, Adler J, Cox R, et al: Linear Accelerator-based stereotaxic radiosurgery for brain metastases: the influence of number of lesion on survival. J. Clin. Oncol. 14: 1085-1092, 1992.
35) Flickinger J, Kondziolka D, Lunsford L, et al: A multi-institutional experience with stereotactic radiosurgery for solitary brain metastasis. Int. J. Radiat. Oncol. Biol. Phys. 28: 797-802, 1994.
36) Shaw E, Scott C, Souhami L, et al: Radiosurgery for the treatment of previously irradiated recurrent primary brain tumors and brain metastasis: initial report of Radiation Therapy Oncology Group protocol 90-05. Int. J. Radiat. Oncol. Biol. Phys. 34: 647-654, 1996.
P.1678 掲載の参考文献
1) Perez CA, Presant CA, Van Amburg AL III: Management of superior vena cava syndrome. Semin. Oncol. 5: 123-134, 1978.
2) 今泉宗久, 渡辺英世, 竹内誠次郎: 上大静脈症候群の診断と治療指針. 外科治療 72: 1-7, 1995.
3) 呉屋朝幸: 縦隔腫瘍とクリティカルケア(土屋了介編) , 第1版, 中外医学社, 東京, 1991, pp. 152-160.
4) Ehrlich W, Ballon HC, Graham EA: Superior vena caval obstruction with a consideration of the possibl relief of symptoms by mediastinal decopression. J. Thorac. Surg. 3: 352-364, 1934.
5) Glover DJ, Grabelsky S, Glick JH: Oncological emergencies and special complications. In Medical Oncology (eds by Calabresi P, Schein PS) , 2nd Ed, McGraw-Hill, New York, 1993, pp. 1021-1072.
12) Carabell SC, Goodman RL: Oncologic emergencies: Superior vena cava syndrome. In Cancer-Principles and Practice of Oncology (eds by DeVita VT, Hellman S, Rosenverg SA) , 2nd Ed, JB Lippincott, Philadlphia, 1985, pp. 1855-1860.
22) Baker GL, Barnes HJ: Superior vena cava syndrome: etiology, diagnosis, and tretment. Am. J. Crit. Care 1: 54-64, 1992.
24) Rosch J, Bedell JE, Putnam J, et al: Gianturco expandable wire stents in the treatment of superior vena cava syndrome recurring after maximum-tolerance radiation. Cancer 60: 1243-1246, 1987.
P.1687 掲載の参考文献
1) 池田恭治: 悪性腫瘍に伴う高カルシウム血症. Annual Review内分泌代謝, p. 1-7, 1996.
2) Mondy GR, Ibbottson KJ, D 'Souoza SM, et al: The hypercalcemia of cancer: Clinical implications and pathogenetic mechanisms. N. Engl. J . Med. 310: 1718-1727, 1984.
3) Holic MF, Krane SM, Potts JT: Calcium, Phosphorus and Bone metabolism: Calcium regulating hormones. In: Harrison 's Principles of Internal Medicine, McGraw Hill, 1991, pp. 1888-1902.
4) Bushinsky DA, Krieger NS: Integration of calcium metabolism in the adult. In: Disorders of Bone and Mineral Metabolism(ed. by Coe FL, Favou MJ) Ravan Press, New York, 1992, pp. 417-432.
7) 佐藤幹二: 高カルシウム血症Q&A-悪性腫瘍による高カルシウム血症を中心に-. 医薬ジャーナル社, 大阪, 1996, pp. 20-25, 28, 29.
14) Morendino Jr JJ, Insogna KL, Nilstone LM, et al: A parathyroid hormone-like protein from cultured human keratinocytes. Science 231: 388-390, 1986.
19) Southby J, Kissen MW, Danks JA, et al: Immunohistochemical localization of parathyroid hormone-related protein in human breast cancer. Cancer Res. 50: 7710-7716, 1990.
20) Powell GL, Southby J, Danks JA, et al: Localization of parathyroid hormone-related protein in breast cancer metastases; Increased incidence in bone compared with other sites. Cancer Res. 51: 3059-3061, 1991.
26) Garett IR, Durie BG, Nedwin GE, et al: Production of lymphotoxin, a bone resorbing cytokine, by cultured human myeloma cells. N. Engl. J. Med. 317: 526-532, 1987.
27) Kawano M, Yamamoto I, Iwato K: Interleukin-I beta rather than lymphotoxin as a major bone resorbing activity in multiple myeloma. Blood 73: 1646-1649, 1989.
30) Sato K, Fuj ii Y, Kasano K, et al: Parathyroid hormone-related protein and interleukin 1 alpha synergistically stimulate bone resorption in vitro and increase the serum calcium concentration in mice in vivo. Endocrinology 124: 2172-2178, 1989.
31) Engelmann H, Holtmann H, Brakebush C, et al: Antibodies to a soluble form of a tumor necrosis factor(TNF) receptor have TNF-like activity. J. Biol. Chem. 265: 14497-14504, 1990.
34) Singer FR, Sharp Jr CF, Rude PK I Pathogenesis of hypercalcemia in malignancy. Miner. Electrolyte Metab. 2: 161-178, 1979.
35) Myers WPL: Hypercalcemia associated with malignant disease. In: Endocrine hormone-producing tumors. Year Book Medical, Chicago, 1973, pp. 147-171.
36) 木村 哲, 佐藤 豊, 阿部 薫: 腫瘍随伴高カルシウム血症. 腫瘍随伴症候群(井村裕夫, 高久史磨編) , サイエンスフォーラム, 第1版, 東京, 1987, pp. 85-100.
37) Vassilopoulou-Sellin R, Newman BM, Taylor SH, et al: Incidence of hypercalcemia in patients with malignancy referred to a comprehensive cancer center. Cancer 71: 1309-1312, 1993.
38) Strewler GJ, Rossenblatt M: Mineral Metabolism. In: Endocrinology and metabolism (3rd ed) . McGraw-Hill, 1995, pp. 1407-1474.
39) 木村 哲, 永田直一, 江藤澄哉・他: 癌患者における高カルシウム血症の治療に関する研究. 厚生省がん研究助成金による研究報告集, 昭和61年度, pp. 264-268.
41) 福本誠二, 池田恭治, 竹内靖博・他: IRMA法による血漿PTH-related protein(PTHrP) 測定の基礎的および臨床的検討. ホルモンと臨床 40: 1309-1314, 1992.
45) 福永仁夫, 大塚信昭, 小野史磨人・他: 1型コラーゲン・Cross-linked Carboxyterminal Telepeptide(1CTP) の血中濃度の測定. ホルモンと臨床 41: 729-736, 1993.
48) Hosking D, Cowley A, Bucknall C, et al: Rehydration in the treatment of severe hypercalcemia. Q. J. Med. 50: 473-481, 1981.
50) 佐藤幹二: 悪性腫瘍と高カルシュウム血症. 医薬ジャーナル33: 133-139, 1997.
51) Fleish H: Bisphosphonates: a new class drugs in diseases of bone and calcium metabolism. Recent Results Cancer Res. 116: 1-28, 1989.
55) Boonenkamp PM, van der Wee-pals LJA, van Wijk-van Lennep MML, et al: Two modes of action of bisphosphonates on osteoclastic resorption of mineralized matrix. Bone Miner. 1: 27-39, 1986.
58) 松本俊夫, 藤田拓男, 森井浩世・他: 悪性腫瘍に伴う高カルシウム血症患者におけるPamidoronate disodium(AHPr-BP) の用量設定試験. 臨床医薬 8: 605-629, 1992.
59) 江藤澄哉, 服部理男, 富田明夫・他: 悪性腫瘍における高カルシウム血症患者におけるアレンドロネート注射剤の有用性検討Prog. Med. 14: 2869-2882, 1994.
60) 佐藤幹二, 服部理男, 富田明夫・他: 悪性腫瘍に伴う高カルシウム血症患者におけるアレンドロネート注射剤の容量設定試験. Prog. Med. 14: 2883-2906, 1994.
61) 松本俊夫, 武部和男, 石井 淳・他: 悪性腫瘍に伴う高カルシウム血症患者におけるYM-175の用量設定試験. 臨床と研究 71: 3263-3280, 1994.
62) 松本俊夫, 永田直一, 堀越 昇・他: 悪性腫瘍に伴う高カルシウム血症患者におけるYM-175とエルカトニンの比較試験. 臨床成人病 25: 383-396, 1995.
63) 池田恭治: 私信による.
64) 芝 英一, 井上共生, 赤沢健司・他: オクトレオチドが奏効した進行乳癌に伴う高カルシウム血症の一例. 癌と化学療 法 23: 343-347, 1996.
P.1693 掲載の参考文献
1) 井形高明: 脊椎・脊髄損傷. 標準整形外科学(第6版) (寺山和雄, 広畑和志監修) , 医学書院, 東京, 1996, pp. 638- 657.
2) 日本整形外科学会骨軟部腫瘍委員会: 全国骨腫瘍患者登録一覧表 (平成7年度) . 国立がんセンター, 1997.
3) 白井康正: 脊髄損傷の褥創. 今日の整形外科治療指針 (山内裕雄・他編集) , 医学書院, 東京, 1995, pp. 264-265.
5) 芝本雄太, 阿部光幸: 骨転移に対する放射線療法. 新図説臨床整形外科講座13, 骨・軟部腫瘍および類似疾患. メジカルビュー社, 東京, 1995, pp. 124-126.
6) Kevin D, Haarington MD: Orthopedic Management of Metastatic Bone Disease. C. V. Mosby, st. Louis 1988, pp. 83-94.
7) 伊藤淳二, 原田征行: 椎体前方成分の腫瘍, 椎弓(後方成分) の腫瘍. 整形外科手術9(黒川高秀編) , 中山書店, 東京, 1995, pp. 147-154.

最近チェックした商品履歴

Loading...