極論で語る緩和ケア

出版社: 丸善出版
著者:
発行日: 2023-10-30
分野: 臨床医学:一般  >  癌/腫瘍一般
ISBN: 9784621308486
電子書籍版: 2023-10-30 (電子書籍版)
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プライマリ緩和ケアは全ての医師が身につけるべき基礎知識
植村健司医師が唱える緩和ケアは明解です。「苦痛(痛み)の緩和」「治療のゴールの話し合いと設定」「ケアの調整」。これらはがんの緩和ケアだけでなく、全ての重症疾患が対象になります。臨床において「これって、本当に患者さんのためになっているのだろうか?」と疑問に思った時こそ、緩和ケアが必要なのです。生活の質の向上、機能の保持、家族の負担の軽減など、患者や家族の価値観に寄り添い、治療のゴールを共に考え、適切に介入します。

目次

  • 第1部 緩和ケア総論
     1章 緩和ケアとは?[What is palliative care?]
      極論1 緩和ケアはがんだけでなく,全ての重症疾患が対象
      極論2 緩和ケアは終末期だけにあらず
      極論3 プライマリ緩和ケアは全ての医師が身につけるべき知識
      極論4 生命延長だけがゴールではない
      コラム1 ホスピス・緩和ケアの母
      コラム2 日本における緩和ケアの発展

     2章 予後の予測[prognostication] 
      極論1 終末期病を見逃すな
      極論2 危篤状態でも治癒の可能性は過少評価しない
      極論3 大きく4つのトラジェクトリ―を把握せよ
      極論4 緩和ケアはよりよく生きるためにあり
      コラム1 小児緩和ケアでは意思決定や死の説明が難しい

     3章 死の過程[imminent death] 
      極論1 死の過程は進行性かつ不可逆性である
      極論2 治療のゴールを確認する
      極論3 躊躇せず集中的症状緩和を試みる
      極論4 comfort feedingで患者と家族をケア
      極論5 緩和的鎮静の深さはRASSで測る
      コラム1 在宅での看取り
      コラム2 死の過程で生じる症状と対処法

     4章 コミュニケーション[communication]
      極論1 コミュニケーションのプロとして治療のゴールを話し合う
      極論2 キャパシティーは判断内容と時間に依存する
      極論3 「代理意思決定は複雑で難しい」と知る
      極論4 コミュニケーションスキルで感情に対処する
      極論5 SDMはソムリエの作業に似ている
      コラム1 ヘッドラインと沈黙の効果
      コラム2 ACP の進め方

     5章 精神的症状・機能障害[psychiatric symptoms & functional impairment]
      極論1 重症疾患患者にうつ症状は多いが見逃しも多い
      極論2 不安には非薬物療法も有効
      極論3 せん妄はキャムの流れで評価
      極論4 ADLとIADLで機能障害の低下を評価する
      コラム1 不眠

    第2部:疾患別の緩和ケア
     6章 認知症[dementia]  
      極論1 認知症は死に至る病である
      極論2 末期認知症患者を見逃すな
      極論3 体重減少・嚥下障害にPEGやTPNはNO
      極論4 痛みはあるが,その痛みは無言
      極論5 定時投与で認知症患者の痛みをコントロール
      コラム1 認知症患者はどのように亡くなるのか?
      コラム2 認知症の留意点

     7章 が ん[malignant tumor]
      極論1 進行した固形がんは早期から緩和ケアする
      極論2 がんの治療目的を患者と一緒に考える
      極論3 緩和目的の放射線治療はその目的を明確にする
      極論4 他科専門医を巻き込んで包括的なケアを提供
      極論5 急変する血液がんは事前準備がとにかく大事
      コラム1  嘔気について
      コラム2 頭頸部がんはつらい症状が多く,多くの専門科との連携が必要
     
     8章 心不全[heart failure]
      極論1 心不全の死期予測はとにかく難しい
      極論2 最も効果のある緩和ケアは心不全の治療
      極論3 ゴールの話し合いも「最善を望み,最悪に備える」
      極論4 終末期ではICDの停止も検討する
      コラム1 destination therapyの是非

     9章 肺疾患 [lung disease]
      極論1 呼吸困難には全人的な評価・介入が必要
      極論2 急性・慢性・強度・生活への影響で評価する
      極論3 呼吸困難の緩和は原疾患の診断・治療を優先する
      極論4 オピオイドは効果を見極めながら慎重に行う
      極論5 人工呼吸器の中止は患者・家族の権利 
      コラム1 意思疎通できない患者はRDOSで評価
      コラム2 COPDの緩和ケア

     10章 腎不全[kidney failure] 
      極論1 血液透析は万能ではない
      極論2 腎不全患者のACPは緩和ケア医を巻き込む
      極論3 腎不全患者の痛みを見逃さない
      極論4 安全に使用できるオピオイドを知っておく
      極論5 透析中止の判断は慎重に.予後プロセスも説明する
      コラム1 透析を導入しない選択肢(+緩和ケア)もある

     11章 痛みの処方箋(オピオイド基本編) [Pain management: Opioids part 1]  
      極論1 「オピオイドナイーブ」と「オピオイド常用者」に分けて考える
      極論2 短時間作用型モルヒネは4時間効果が持続する
      極論3 痛みの波に応じてレスキュー.目安は1時間毎
      極論4 オピオイドローテーションはオピオイド治療の要 
      極論5 オピオイドローテーションの黄金律をマスターする
      コラム1 持続静注か,間欠静注か

     12章 痛みの処方箋(オピオイド応用編) [Pain management: Opioids part 2]
      極論1 オピオイドの副作用は3つのキモを押さえる
      極論2 PCAの有用性と禁忌を知る
      極論3 PCAの持続速度変更は原則24時間以上経ってから
      極論4 フェンタニルを使いこなす
      極論5 パッチは血中濃度の把握が大事
      コラム1 見逃されがちな副作用
      コラム2 フェンタニルパッチ
      コラム3 神経障害性疼痛
      コラム4 非がん性慢性疼痛

この書籍の参考文献

参考文献のリンクは、リンク先の都合等により正しく表示されない場合がありますので、あらかじめご了承下さい。

本参考文献は電子書籍掲載内容を元にしております。

第1部 緩和ケア総論

P.14 掲載の参考文献
1) Palliative Care Definition (https://www.capc.org/about/palliative-care).
2) Kelley AS, Bollens-Lund E. Identifying the Population with Serious Illness : The "Denominator" Challenge. J Palliat Med. 2018 ; 21 : S7-16.
3) David Clark. Cicely Saunders : A Life and Legacy. Oxford University Press, 2018.
4) National Hospice and Palliative Care Organization. NHPCO Facts and Figures, 2021 edition. 2021 Oct.
5) Temel JS, Greer JA, et al. Early Palliative Care for Patients with Metastatic Non-Small-Cell Lung Cancer. N Engl J Med. 2010 ; 363 (8) : 733-42.
6) Ferrell BR, Temel JS, et al. Integration of Palliative Care Into Standard Oncology Care : American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol. 2017 ; 35 : 96-112.
7) Morrison RS, Penrod JD, et al. Cost savings associated with US hospital palliative care consultation programs. Arch Intern Med. 2008 ; 168 (16) : 1783-90.
8) CAPC. Reports and Publications (https://www.capc.org/capc-reports-and-publications).
9) 五十嵐尚子, 宮下光令. データでみる日本の緩和ケアの現状 (https://hospat.org/assets/templates/hospat/pdf/hakusyo_2019/2019-2-1.pdf).
10) Kamal AH, Bull JH, et al. Future of the Palliative Care Workforce : Preview to an Impending Crisis. Am J Med. 2017 ; 130 (2) : 113-4.
11) Charon R. Narrative Medicine : Honoring the Stories of Illness. Oxford University Press ; 2008.
P.25 掲載の参考文献
1) Hui D, Nooruddin Z, et al. Concepts and definitions for "actively dying," "end of life," "terminally ill," "terminal care," and "transition of care" : a systematic review. J Pain Symptom Manage. 2014 ; 47 : 77-89.
2) Taylor LJ, Nabozny MJ, et al. A Framework to Improve Surgeon Communication in High-Stakes Surgical Decisions : Best Case/Worst Case. JAMA Surg. 2017 ; 152 : 531-38.
3) Zimmermann CJ, Zelenski A, et al. Best Case/Worst Case ICU : Using Clinician Input to Adapt a Communication Tool to Assist Older Trauma Patients with Poor Prognosis. J Am Coll Surg. 2019 ; 229 : S289.
4) 樋口雅也, 植村健司 (著), 反田篤志 (監修). あめいろぐ高齢者医療. 丸善出版, 2020.
5) Murray SA, Kendall M, et al. Illness trajectories and palliative care. BMJ. 2005 ; 330 : 1007-11.
6) Jang RW, Caraiscos VB, et al. Simple prognostic model for patients with advanced cancer based on performance status. J Oncol Pract. 2014 ; 10 : e335-41.
7) Smith AK, Micco G. Serving the Very Sick, Very Frail, and Very Old : Geriatrics, Palliative Care, and Clinical Ethics. Perspect Biol Med. 2017 ; 60 : 503-18.
P.40 掲載の参考文献
1) Weissman DE. Syndrome of Imminent Death. In : Palliative Care Network of Wisconsin (https://www.mypcnow.org/fast-fact/syndrome-of-imminent-death).
2) Ellershaw J, Ward C. Care of the dying patient : the last hours or days of life. BMJ 2003 ; 326 (7379) : 30-4.
3) Alsuhail AI, Punalvasal Duraisamy B, et al. The Accuracy of Imminent Death Diagnosis in a Palliative Care Setting. Cureus 2020 ; 12 (8) : e9503.
4) Lundquist G, Rasmussen BH, et al. Information of imminent death or not : does it make a difference? J Clin Oncol 2011 ; 29 (29) : 3927-31.
5) Macauley RC. Ethics in Palliative Care : A Complete Guide. In : Ethics in Palliative Care. Oxford University Press ; 2018.
6) Krakauer EL, Penson RT, et al. Sedation for intractable distress of a dying patient : acute palliative care and the principle of double effect. Oncologist 2000 ; 5 (1) : 53-62.
7) 森田達也, 田代志門 (編著). 鎮静と安楽死のグレーゾーンを問う-医学・看護学・生命倫理学・法学の視点. 中外医学社, 2023.
8) Morita T, Hyodo I, et al. Association between hydration volume and symptoms in terminally ill cancer patients with abdominal malignancies. Ann Oncol 2005 ; 16 (4) : 640-7.
9) McCann RM, Hall WJ, Groth-Juncker A. Comfort care for terminally ill patients. The appropriate use of nutrition and hydration. JAMA 1994 ; 272 (16) : 1263-6.
10) Palecek EJ, Teno JM, et al. Comfort feeding only : a proposal to bring clarity to decision-making regarding difficulty with eating for persons with advanced dementia. J Am Geriatr Soc 2010 ; 58 (3) : 580-4.
11) Bruera E, Hui D, et al. Parenteral hydration in patients with advanced cancer : a multicenter, double-blind, placebo-controlled randomized trial. J Clin Oncol 2013 ; 31 (1) : 111-8.
12) Weissman DE. Subcutaneous Opioid Infusions. In : Palliative Care Network of Wisconsin (https://www.mypcnow.org/fast-fact/subcutaneous-opioid-infusions).
13) Rousseau P. Palliative sedation in the management of refractory symptoms. J Support Oncol 2004 ; 2 (2) : 181-6.
14) Lo B, Rubenfeld G. Palliative sedation in dying patients : "we turn to it when everything else hasn't worked." JAMA 2005 ; 294 (14) : 1810-6.
15) Cheng C, Roemer-Becuwe C, et al. When midazolam fails. J Pain Symptom Manage 2002 ; 23 (3) : 256-65.
16) Maltoni M, Scarpi E, et al. Palliative sedation in end-of-life care and survival : a systematic review. J Clin Oncol 2012 ; 30 (12) : 1378-83.
17) Hui D, Frisbee-Hume S, et al. Effect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care : A Randomized Clinical Trial. JAMA 2017 ; 318 (11) : 1047-56.
18) Hui D. Benzodiazepines for agitation in patients with delirium : selecting the right patient, right time, and right indication. Curr Opin Support Palliat Care 2018 ; 12 (4) : 489-94.
19) Buss MK, Vanderwerker LC, et al. Associations between caregiver-perceived delirium in patients with cancer and generalized anxiety in their caregivers. J Palliat Med 2007 ; 10 (5) : 1083-92.
20) Kerr CW, Donnelly JP, et al. End-of-life dreams and visions : a longitudinal study of hospice patients' experiences. J Palliat Med 2014 ; 17 (3) : 296-303.
P.59 掲載の参考文献
1) Mack JW, et al. Associations between end-of-life discussion characteristics and care received near death : a prospective cohort study. J Clin Oncol. 2012 ; 30 (35) : 4387-95.
2) Wright AA, Zhang B, et al. Associations between end-of-life discussions, patient mental health, medical care near death, and caregiver bereavement adjustment. JAMA. 2008 ; 300 (14) : 1665-73.
3) Scheunemann LP, Ernecoff NC, et al. Clinician-Family Communication About Patients' Values and Preferences in Intensive Care Units. JAMA Intern Med 2019 ; 179 (5) : 676-84.
4) Schenker Y, Crowley-Matoka M, et al. I don't want to be the one saying "we should just let him die" : intrapersonal tensions experienced by surrogate decision makers in the ICU. J Gen Intern Med 2012 ; 27 (12) : 1657-65.
5) Azoulay E, Pochard F, et al. Risk of post-traumatic stress symptoms in family members of intensive care unit patients. Am J Respir Crit Care Med 2005 ; 171 (9) : 987-94.
6) Zier LS, Burack JH, et al. Surrogate decision makers' responses to physicians' predictions of medical futility. Chest 2009 ; 136 (1) : 110-7.
7) アンソニー・バック, ロバート・アーノルド, 他 (著), 植村健司 (訳). 米国緩和ケア医に学ぶ医療コミュニケーションの極意. 中外医学社, 2018.
8) 伊藤香, 大内啓 (著). 新訂版 緊急ACP悪い知らせの伝え方, 大切なことの決め方. 医学書院, 2022.
9) McDonagh JR, Elliott TB, et al. Family satisfaction with family conferences about end-of-life care in the intensive care unit : Increased proportion of family speech is associated with increased satisfaction*. Crit Care Med 2004 ; 32 (7) : 1484-8.
10) Lu E, Nakagawa S. A "Three-Stage Protocol" for Serious Illness Conversations : Reframing Communication in Real Time. Mayo Clin Proc.
11) Childers JW, Back AL, et al. REMAP : A Framework for Goals of Care Conversations. J Oncol Pract 2017 ; 13 (10) : e844-50.
12) Nakagawa S, Callahan ME, et al. Patient Values : Three Important Questions-Tell me more? Why? What else? BMJ Support Palliat Care. 2023 ; spcare-2023-004302.
P.76 掲載の参考文献
1) Massie MJ. Prevalence of depression in patients with cancer. J Natl Cancer Inst Monogr 2004 ; (32) : 57-71.
2) Hotopf M, Chidgey J, et al. Depression in advanced disease : a systematic review Part 1. Prevalence and case finding. Palliat Med 2002 ; 16 (2) : 81-97.
3) Palmer S, Vecchio M, et al. Prevalence of depression in chronic kidney disease : systematic review and meta-analysis of observational studies. Kidney Int 2013 ; 84 (1) : 179-91.
4) Kozlov E, Dong X, et al. The Epidemiology of Depressive Symptoms in the Last Year of Life. J Am Geriatr Soc 2020 ; 68 (2) : 321-8.
5) Satin JR, Linden W, Depression as a predictor of disease progression and mortality in cancer patients : a meta-analysis. Cancer 2009 ; 115 (22) : 5349-61.
6) Goldstein NE, Sean Morrison R. Evidence-Based Practice of Palliative Medicine. Elsevier Health Sciences ; 2012.
8) Snaith RP. The Hospital Anxiety And Depression Scale. Health Qual Life Outcomes 2003 ; 1 : 29.
9) Huynh NN, McIntyre RS. What Are the Implications of the STAR*D Trial for Primary Care? A Review and Synthesis. Prim Care Companion J Clin Psychiatry. 2008 ; 10 : 91-6.
10) Banerjee S, High J, et al. Study of mirtazapine for agitated behaviours in dementia (SYMBAD) : a randomised, double-blind, placebo-controlled trial. Lancet. 2021 ; 398 : 1487-97.
11) Trivedi MH, Fava M, et al. Medication augmentation after the failure of SSRIs for depression. N Engl J Med 2006 ; 354 (12) : 1243-52.
12) Zhou X, Keitner GI, et al. Atypical Antipsychotic Augmentation for Treatment-Resistant Depression : A Systematic Review and Network Meta-Analysis. Int J Neuropsychopharmacol. 2015 ; 18 (11) : pyv060.
13) Lenze EJ, Mulsant BH, et al. Efficacy, safety, and tolerability of augmentation pharmacotherapy with aripiprazole for treatment-resistant depression in late life : a randomised, double-blind, placebo-controlled trial. Lancet 2015 ; 386 (10011) : 2404-12.
14) Olin J, Masand P. Psychostimulants for depression in hospitalized cancer patients. Psychosomatics. Jan-Feb 1996 ; 37 (1) : 57-62.
15) Spitzer RL, Kroenke K, et al. A brief measure for assessing generalized anxiety disorder : the GAD-7. Arch Intern Med 2006 ; 166 (10) : 1092-7.
16) Markota M, Morgan RJ. Treatment of Generalized Anxiety Disorder with Gabapentin. Case Rep Psychiatry 2017 ; 2017 : 6045017.
17) Inouye SK, van Dyck CH, et al. Clarifying confusion : the confusion assessment method. A new method for detection of delirium. Ann Intern Med. 1990 ; 113 (12) : 941-8.
18) Inouye SK. Delirium in Older Persons. N Engl J Med. 2006 ; 354 (11) : 1157-65.
19) Girard TD, Exline MC, et al. Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness. N Engl J Med 2018 ; 379 (26) : 2506-16.
20) Lonergan E, Britton AM, et al. Antipsychotics for delirium. Cochrane Database Syst Rev 2007 ; (2) : CD005594.
21) Huybrechts KF, Gerhard T, et al. Differential risk of death in older residents in nursing homes prescribed specific antipsychotic drugs : population based cohort study. BMJ 2012 ; 344 : e977.
22) Gill SS, Bronskill SE, et al. Antipsychotic drug use and mortality in older adults with dementia. Ann Intern Med 2007 ; 146 (11) : 775-86.
23) Weintraub D, Chiang C, et al. Association of Antipsychotic Use With Mortality Risk in Patients With Parkinson Disease. JAMA Neurol 2016 ; 73 (5) : 535-41.
24) Murray-Thomas T, Jones ME, et al. Risk of mortality (including sudden cardiac death) and major cardiovascular events in atypical and typical antipsychotic users : a study with the general practice research database. Cardiovasc Psychiatr y Neurol 2013 ; 2013 : 247486.
25) 樋口雅也, 植村健司 (著), 反田篤司 (監修). あめいろぐ高齢者医療. 丸善出版, 2020.

第2部 疾患別の緩和ケア

P.96 掲載の参考文献
1) Lynn J, Adamson DM. Living well at the end of life : Adapting health care to serious chronic illness in old age. January 2003.
2) Susan L Mitchell. Advanced Dementia. N Engl J Med. 2015 ; 373 (13) : 1276-7.
3) Mitchell SL, Teno JM, et al. The Clinical Course of Advanced Dementia. N Engl J Med 2009 ; 361 : 1529-38.
4) Amjad H, Roth DL, et al. Underdiagnosis of Dementia : an Observational Study of Patterns in Diagnosis and Awareness in US Older Adults. J Gen Intern Med. 2018 ; 33 : 1131-8.
5) Lang L, Clifford A, et al. Prevalence and determinants of undetected dementia in the community : a systematic literature review and a meta-analysis. BMJ Open. 2017 ; 7 : e011146.
6) Hanrahan P, Raymond M, et al. Criteria for enrolling dementia patients in hospice : a replication. Am J Hosp Palliat Care. 1999 ; 16 : 395-400.
7) Choosing Wisely (AGS) : Ten Things Physicians and Patients Should Question (https://www.healthinaging.org/sites/default/files/pdf/Choosing.Wisely.Ten_.Things.pdf).
8) Masaki S, Kawamoto T. Comparison of long-term outcomes between enteral nutrition via gastrostomy and total parenteral nutrition in older persons with dysphagia : A propensity-matched cohort study. PLoS One. 2019 ; 14 : e0217120.
9) 樋口雅也, 植村健司 (著), 反田篤志 (監修). あめいろぐ高齢者医療. 丸善出版, 2020.
10) Wirth R, Smoliner C, et al. Guideline clinical nutrition in patients with stroke. Exp Transl Stroke Med. 2013 ; 5 : 14.
11) van der Steen JT, Lane P, et al. Antibiotics and mortality in patients with lower respiratory infection and advanced dementia. J Am Med Dir Assoc. 2012 ; 13 : 156-61.
12) van Kooten J, Smalbrugge M, et al. Prevalence of Pain in Nursing Home Residents : The Role of Dementia Stage and Dementia Subtypes. J Am Med Dir Assoc. 2017 ; 18 : 522-7.
13) Malara A, De Biase GA, et al. Pain Assessment in Elderly with Behavioral and Psychological Symptoms of Dementia. J Alzheimers Dis. 2016 ; 50 : 1217-25.
14) Reus VI, Fochtmann LJ, et al. The American Psychiatric Association Practice Guideline on the Use of Antipsychotics to Treat Agitation or Psychosis in Patients With Dementia. Am J Psychiatry. 2016 ; 173 : 543-46.
15) Warden V, Hurley AC, et al. Development and psychometric evaluation of the Pain Assessment in Advanced Dementia (PAINAD) scale. J Am Med Dir Assoc. 2003 ; 4 (1) : 9-15.
16) Jordan A, Hughes J, et al. The utility of PAINAD in assessing pain in a UK population with severe dementia. Int J Geriatr Psychiatry. 2011 ; 26 : 118-26.
17) Sutor B, Rummans TA, et al. Assessment and management of behavioral disturbances in nursing home patients with dementia. Mayo Clin Proc. 2001 ; 76 : 540-50.
18) Wynn ZJ, Cummings JL. Cholinesterase inhibitor therapies and neuropsychiatric manifestations of Alzheimer's disease. Dement Geriatr Cogn Disord. 2004 ; 17 : 100-8.
19) Aarsland D, Pahlhagen S, et al. Depression in Parkinson disease--epidemiology, mechanisms and management. Nat Rev Neurol. 2011 ; 8 : 35-47.
20) Chiu P-Y, Wang C-W, et al. Depression in dementia with Lewy bodies : A comparison with Alzheimer's disease. PLoS One. 2017 ; 12 : e0179399.
21) Cole CS, Carpenter JS, et al. Pain trajectories of nursing home residents. J Am Geriatr Soc. 2023 Apr ; 71 (4) : 1188-97.
22) Gjerstad MD, Wentzel-Larsen T, et al. Insomnia in Parkinson's disease : frequency and progression over time. J Neurol Neurosurg Psychiatry. 2007 ; 78 : 476-9.
23) Twillman RK, Long TD, et al. Treatment of painful skin ulcers with topical opioids. J Pain Symptom Manage. 1999 ; 17 : 288-92.
24) Bale S, Tebbie N, et al. A topical metronidazole gel used to treat malodorous wounds. Br J Nurs. 2004 ; 13 : S4-11.
25) Fernandez HH, Wu C-K, et al. Pharmacotherapy of dementia with Lewy bodies. Expert Opin Pharmacother. 2003 ; 4 : 2027-37.
26) Mitchell SL. Care of patients with advanced dementia. In : Sean Morrison R, Wilterdink JL, editors. UpToDate. Waltham, MA : UpToDate ; 2023.
P.118 掲載の参考文献
1) Ferrell BR, Temel JS, et al. Integration of Palliative Care Into Standard Oncology Care : American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol. 2017 ; 35 : 96-112.
2) Temel JS, Greer JA, et al. Early Palliative Care for Patients with Metastatic Non-Small-Cell Lung Cancer. N Engl J Med. 2010 ; 363 (8) : 733-42.
3) Hui D, Bruera E. The Edmonton Symptom Assessment System 25 Years Later : Past, Present, and Future Developments. J Pain Symptom Manage. 2017 ; 53 (3) : 630-643.
4) Yokomichi N, Morita T, et al. Validation of the Japanese Version of the Edmonton Symptom Assessment System-Revised. J Pain Symptom Manage. 2015 ; 50 (5) : 718-23.
5) https://www.ncc.go.jp/jp/ncce/clinic/psychiatry/040/ESAS-r-J.pdf.
6) Cross SH, Warraich HJ. Changes in the Place of Death in the United States. N Engl J Med. 2019 ; 381 (24) : 2369-70.
7) Taniguchi Y, Iwagami M, et al. National trends in the proportion of in-hospital deaths by cause of death among older adults with long-term care : a nationwide observational study in Japan from 2007 to 2017. BMC Geriatr. 2022 ; 22 (1) : 6.
8) Oken MM, Creech RH, et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 1982 ; 5 : 649-55.
9) Dall'Olio FG, Maggio I, et al. ECOG performance status ? 2 as a prognostic factor in patients with advanced non small cell lung cancer treated with immune checkpoint inhibitors-A systematic review and meta-analysis of real world data. Lung Cancer. 2020 Jul ; 145 : 95-104.
10) Wood GJ, Shega JW, et al. Management of intractable nausea and vomiting in patients at the end of life : "I was feeling nauseous all of the time... nothing was working". JAMA. 2007 Sep 12 ; 298 (10) : 1196-207.
11) Goldstein NE, Sean Morrison R. Evidence-Based Practice of Palliative Medicine. Elsevier Health Sciences, 2012.
12) 日本癌治療学会. 制吐療法 がん診療ガイドライン (http://www.jsco-cpg.jp/guideline/29.html).
13) Jordan K, Sippel C, et al. Guidelines for antiemetic treatment of chemotherapy-induced nausea and vomiting : past, present, and future recommendations. Oncologist. ; 12 (9) : 1143-50.
14) Maria F, Weinberg R, et al. Olanzapine for Nausea, Delirium, Anxiety, Insomnia, and Cachexia #315. J Palliat Med. ; 19 (11) : 1224-5 (https://www.mypcnow.org/fast-fact/olanzapine-for-nausea-delirium-anxiety-insomnia-and-cachexia/).
15) Chow R, Hoskin P, et al. Single vs multiple fraction palliative radiation therapy for bone metastases : Cumulative meta-analysis. Radiother Oncol. 2019 ; 141 : 56-61.
16) Van Den Hout WB, Van Der Linden YM, et al. Single- versus multiple-fraction radiotherapy in patients with painful bone metastases : cost-utility analysis based on a randomized trial. J Natl Cancer Inst. 2003 ; 95 (3) : 222-9.
17) Van Der Linden YM, Steenland E, et al. Patients with a favourable prognosis are equally palliated with single and multiple fraction radiotherapy : results on survival in the Dutch Bone Metastasis Study. Radiother Oncol. 2006 ; 78 (3) : 245-53.
18) Obita GP, Boland EG, et al. Somatostatin Analogues Compared With Placebo and Other Pharmacologic Agents in the Management of Symptoms of Inoperable Malignant Bowel Obstruction : A Systematic Review. J Pain Symptom Manage. 2016 ; 52 (6) : 901-919. e1.
19) Egan PC, Belanger E, et al. Comparison of End-of-Life Care Quality Outcomes and Indicators of Palliative Needs between Medicare Beneficiaries with Solid and Hematologic Malignancies. Blood. 2020 ; 136 : 11.
20) Hui D, Didwaniya N, et al. Quality of end-of-life care in patients with hematologic malignancies : a retrospective cohort study. Cancer. 2014 ; 120 (10) : 1572-8.
21) Verhoef M-J, de Nijs EJM, et al. End-of-Life Trajectories of Patients With Hematological Malignancies and Patients With Advanced Solid Tumors Visiting the Emergency Department : The Need for a Proactive Integrated Care Approach. Am J Hosp Palliat Care. 2020 ; 37 (9) : 692-700.
22) Goldstein NE, Sean Morrison R. Evidence-Based Practice of Palliative Medicine : Expert Consult : Online and Print. Elsevier Health Sciences, 2012.
23) Cardenas-Mori J, Vanessa Lewis-Ramos V. Corticosteroids for Common Palliative Care Symptoms. In : Palliative Care Network of Wisconsin (https://www.mypcnow.org/fastfact/corticosteroids-for-common-palliative-care-symptoms).
P.130 掲載の参考文献
2) Mechanical Circulatory Support in Advanced Heart Failure. In : Palliative Care Network of Wisconsin (https://www.mypcnow.org/fast-fact/mechanical-circulatory-support-in-advanced-heart-failure).
3) 日本循環器学会/日本心不全学会合同ガイドライン. 急性・慢性心不全診療ガイドライン (2017年改訂版).
4) Kavalieratos D, Gelfman LP, et al. Palliative Care in Heart Failure : Rationale, Evidence, and Future Priorities. J Am Coll Cardiol. 2017 ; 70 : 1919-30.
5) Rogers JG, Patel CB, et al. Palliative Care in Heart Failure : The PAL-HF Randomized, Controlled Clinical Trial. J Am Coll Cardiol. 2017 ; 70 : 331-41.
6) Chang YK, Allen LA, et al. Criteria for Referral of Patients With Advanced Heart Failure for Specialized Palliative Care. J Am Coll Cardiol. 2022 ; 80 : 332-44.
7) Warraich HJ, Wolf SP, et al. Characteristics and Trends Among Patients With Cardiovascular Disease Referred to Palliative Care. JAMA Netw Open. 2019 ; 2 : e192375.
8) Smith A. State of Heart Failure & Palliative Care : Podcast with Haider Warraich (https://geripal.org/state-of-heart-failure-palliative-care/#transcript).
9) Oxberry SG, Torgerson DJ, et al. Short-term opioids for breathlessness in stable chronic heart failure : a randomized controlled trial. Eur J Heart Fail. 2011 ; 13 : 1006-12.
10) Oxberry SG, Bland JM, et al. Repeat dose opioids may be effective for breathlessness in chronic heart failure if given for long enough. J Palliat Med. 2013 ; 16 : 250-5.
11) O'Connor CM, Jiang W, et al. Safety and efficacy of sertraline for depression in patients with heart failure : results of the SADHART-CHF (Sertraline Against Depression and Heart Disease in Chronic Heart Failure) trial. J Am Coll Cardiol. 2010 ; 56 : 692-9.
12) Angermann CE, Gelbrich G, et al. Effect of Escitalopram on All-Cause Mortality and Hospitalization in Patients With Heart Failure and Depression : The MOOD-HF Randomized Clinical Trial. JAMA. 2016 ; 315 : 2683-93.
13) Funk KA, Bostwick JR. A comparison of the risk of QT prolongation among SSRIs. Ann Pharmacother. 2013 ; 47 : 1330-41.
14) Rochester MP, Kane AM, et al. Evaluating the risk of QTc prolongation associated with antidepressant use in older adults : a review of the evidence. Ther Adv Drug Saf. 2018 ; 9 : 297-308.
15) Lee K, Davis MA, et al. Falls in community-dwelling older adults with heart failure : A retrospective cohort study. Heart Lung. 2020 ; 49 : 238-50.
16) Nizamic T, Murad MH, et al. Ambulatory Inotrope Infusions in Advanced Heart Failure : A Systematic Review and Meta-Analysis. JACC Heart Fail. 2018 ; 6 : 757-67.
P.146 掲載の参考文献
1) Abernethy AP, Wheeler JL. Total dyspnoea. Curr Opin Support Palliat Care. 2008 ; 2 : 110-3.
2) Syouji M, Fujita S. 熟練看護師が行う全人的呼吸困難感を体験しているがん患者のアセスメント. 高知女子大学看護学会誌. 45 : 78-88.
3) Mularski RA, Reinke LF, et al. An official American Thoracic Society workshop report : assessment and palliative management of dyspnea crisis. Ann Am Thorac Soc. 2013 ; 10 : S98-106.
4) Campbell ML, Templin T, et al. A Respiratory Distress Observation Scale for patients unable to self-report dyspnea. J Palliat Med. 2010 ; 13 : 285-90.
5) Zhuang Q, Yang GM, et al. Validity, Reliability, and Diagnostic Accuracy of the Respiratory Distress Observation Scale for Assessment of Dyspnea in Adult Palliative Care Patients. J Pain Symptom Manage. 2019 ; 57 : 304-10.
6) Abernethy AP, McDonald CF, et al. Effect of palliative oxygen versus room air in relief of breathlessness in patients with refractory dyspnoea : a double-blind, randomised controlled trial. Lancet. 2010 ; 376 : 784-93.
7) Kako J, Morita T, Yamaguchi T, et al. Fan Therapy Is Effective in Relieving Dyspnea in Patients With Terminally Ill Cancer : A Parallel-Arm, Randomized Controlled Trial. J Pain Symptom Manage. 2018 ; 56 : 493-500.
8) Pisani L, Hill NS, et al. Management of Dyspnea in the Terminally Ill. Chest. 2018 ; 154 : 925-34.
9) Gosselink R. Controlled breathing and dyspnea in patients with chronic obstructive pulmonary disease (COPD). J Rehabil Res Dev. 2003 ; 40 : 25-33.
10) Obarzanek L, Wu W, et al. Opioid Management of Dyspnea at End of Life : A Systematic Review. J Palliat Med. 2022.
11) Rocker GM, Simpson AC, et al. Opioid therapy for refractory dyspnea in patients with advanced chronic obstructive pulmonary disease : patients' experiences and outcomes. CMAJ Open. 2013 ; 1 : E27-36.
12) Jennings A-L, Davies AN, et al. A systematic review of the use of opioids in the management of dyspnoea. Thorax. 2002 ; 57 : 939-44.
13) Marciniuk DD, Goodridge D, et al. Managing dyspnea in patients with advanced chronic obstructive pulmonary disease : a Canadian Thoracic Society clinical practice guideline. Can Respir J. 2011 ; 18 : 69-78.
14) Currow DC, Agar MR. Benzodiazepine Prescribing in People with Chronic Obstructive Pulmonary Disease : Clinical Considerations. Drugs Aging. 2020 ; 37 : 263-270.
15) Simon ST, Higginson IJ, et al. Benzodiazepines for the relief of breathlessness in advanced malignant and non-malignant diseases in adults. Cochrane Database Syst Rev. 2016 ; 10 : CD007354.
16) Currow DC, McDonald C, et al. Once-daily opioids for chronic dyspnea : a dose increment and pharmacovigilance study. J Pain Symptom Manage. 2011 ; 42 : 388-99.
17) Verberkt CA, van den Beuken-van Everdingen MHJ,, et al. Effect of Sustained-Release Morphine for Refractory Breathlessness in Chronic Obstructive Pulmonary Disease on Health Status : A Randomized Clinical Trial. JAMA Intern Med. 2020 ; 180 (10) : 1306-14.
18) Ekstrom M, Ferreira D, et al. Effect of Regular, Low-Dose, Extended-release Morphine on Chronic Breathlessness in Chronic Obstructive Pulmonary Disease : The BEAMS Randomized Clinical Trial. JAMA. 2022 ; 328 : 2022-32.
19) Currow D, Louw S, et al. Regular, sustained-release morphine for chronic breathlessness : a multicentre, double-blind, randomised, placebo-controlled trial. Thorax. 2020 ; 75 : 50-6.
20) Ferreira DH, Louw S, et al. Controlled-Release Oxycodone vs. Placebo in the Treatment of Chronic Breathlessness-A Multisite Randomized Placebo Controlled Trial. J Pain Symptom Manage. 2019. 2020 ; 59 (3) : 581-9.
21) Mularski RA, Reinke LF, et al. Dyspnea crisis : A consensus definition for a novel clinical entity. Chest. 2010 ; 138 : 233A.
22) Goldstein NE, Sean Morrison R. Evidence-Based Practice of Palliative Medicine. Elsevier Health Sciences ; 2012.
23) Benitez-Rosario MA, Martin AS, Feria M. Oral transmucosal fentanyl citrate in the management of dyspnea crises in cancer patients. J Pain Symptom Manage. 2005 ; 30 : 395-7.
24) 植村健司. 「死ぬ権利 (the right to die) 」にまつわる4つの医療行為-米国における現状とその医療倫理的背景. Brain Nerve. 74 : 181-8.
25) White DB, Arnold RM, et al. Withholding and withdrawing ventilatory support in adults in the intensive care unit. In : UpToDate (https://www.uptodate.com/contents/withholding-and-withdrawing-ventilatory-support-in-adults-in-the-intensive-care-unit).
26) Kennedy IM. The Karen Quinlan case : problems and proposals. J Med Ethics. 1976 ; 2 : 3-7.
27) Robert R, Le Gouge A, et al. Terminal weaning or immediate extubation for withdrawing mechanical ventilation in critically ill patients (the ARREVE observational study). Intensive Care Med. 2017 ; 43 : 1793-1807.
28) Cooke CR, Hotchkin DL, et al. Predictors of time to death after terminal withdrawal of mechanical ventilation in the ICU. Chest. 2010 ; 138 : 289-97.
29) Pan CX, Platis D, et al. How Long Does (S) He Have? Retrospective Analysis of Outcomes After Palliative Extubation in Elderly, Chronically Critically Ill Patients. Crit Care Med. 2016 ; 44 : 1138-44.
30) Gunten CF, Weissman DE. Ventilator Withdrawal Protocol. In : Palliative Care Network of Wisconsin (https://www.mypcnow.org/fast-fact/ventilator-withdrawal-protocol).
31) Downar J, Delaney JW, et al. Guidelines for the withdrawal of life-sustaining measures. Intensive Care Med. 2016 ; 42 : 1003-17.
32) Cook D, Rocker G. Dying with dignity in the intensive care unit. N Engl J Med. 2014 ; 370 : 2506-14.
P.162 掲載の参考文献
1) 透析の開始と継続に関する意思決定プロセスについての提言作成委員会. 透析の開始と継続に関する意思決定プロセスについての提言. 透析会誌 53 (4) : 173-217, 2020.
2) 2017 Annual Data Report. In : National Institute of Diabetes and Digestive and Kidney Diseases (https://www.niddk.nih.gov/about-niddk/strategic-plans-reports/usrds/prior-data-reports/2017).
3) 2013 USRDS Annual Data Report : Mortality. Am J Kidney Dis. 2014 ; 63 : e263-70.
4) 2018 Annual Data Report. In : National Institute of Diabetes and Digestive and Kidney Diseases (https://www.niddk.nih.gov/about-niddk/strategic-plans-reports/usrds/prior-data-reports/2018).
5) 花房規男, 阿部雅紀, 他. わが国の慢性透析療法の現況 (2021年12月31日現在). 透析会誌. 2021 ; 54 : 611-57.
6) Verberne WR, Geers ABMT, et al. Comparative Survival among Older Adults with Advanced Kidney Disease Managed Conservatively Versus with Dialysis. Clin J Am Soc Nephrol 2016 ; 11 (4) : 633-40.
7) Foote C, Kotwal S, et al. Survival outcomes of supportive care versus dialysis therapies for elderly patients with end-stage kidney disease : A systematic review and meta-analysis. Nephrology 2016 ; 21 (3) : 241-53.
8) Kurella Tamura M, et al. Functional status of elderly adults before and after initiation of dialysis. N Engl J Med 2009 ; 361 (16) : 1539-47.
9) Jassal SV, Chiu E, et al. Loss of independence in patients starting dialysis at 80 years of age or older. N Engl J Med 2009 ; 361 (16) : 1612-3.
10) Weisbord SD, Fried LF, et al. Prevalence, severity, and importance of physical and emotional symptoms in chronic hemodialysis patients. J Am Soc Nephrol 2005 ; 16 (8) : 2487-94.
11) Renal Physicians Association. Shared Decision-Making in the Appropriate Initiation of and Withdrawal from Dialysis, Clinical Practice Guideline Second Edition. RPA, 2010.
12) Murtagh FEM, Addington-Hall JM, et al. End-stage renal disease : a new trajectory of functional decline in the last year of life. J Am Geriatr Soc 2011 ; 59 (2) : 304-8.
13) Murtagh FEM, Marsh JE, et al. Dialysis or not? A comparative survival study of patients over 75 years with chronic kidney disease stage 5. Nephrol Dial Transplant 2007 ; 22 (7) : 1955-62.
14) Murtagh FE, Addington-Hall J, et al. Symptoms in the month before death for stage 5 chronic kidney disease patients managed without dialysis. J Pain Symptom Manage 2010 ; 40 (3) : 342-52.
15) Renal Physicians Association. Shared Decision-Making in the Appropriate Initiation of and Withdrawal from Dialysis. Clinical Practice Guideline. Second edition. Rockville, Maryland 2010.
16) Brennan F, Stewart C, et al. Time to Improve Informed Consent for Dialysis : An International Perspective. Clin J Am Soc Nephrol 2017 ; 12 (6) : 1001-9.
17) Weisbord SD, Fried LF, et al. Renal Provider Recognition of Symptoms in Patients on Maintenance Hemodialysis. Clin J Am Soc Nephrol 2007 ; 2 (5) : 960-7.
18) Davison SN. Pain in hemodialysis patients : prevalence, cause, severity, and management. Am J Kidney Dis 2003 ; 42 (6) : 1239-47.
19) Palmer S, Vecchio M, et al. Prevalence of depression in chronic kidney disease : systematic review and meta-analysis of obser vational studies. Kidney Int 2013 ; 84 (1) : 179-91.
20) Hedayati SS, Finkelstein FO. Epidemiology, diagnosis, and management of depression in patients with CKD. Am J Kidney Dis 2009 ; 54 (4) : 741-52.
21) Wilcock A, Charlesworth S, et al. Prescribing Non-Opioid Drugs in End-Stage Kidney Disease. J Pain Symptom Manage 2017 ; 54 (5) : 776-87.
22) Sukul N, Speyer E, et al. Pruritus and Patient Reported Outcomes in Non-Dialysis CKD. Clin J Am Soc Nephrol 2019 ; 14 (5) : 673-81.
23) Rayner HC, Larkina M, et al. International Comparisons of Prevalence, Awareness, and Treatment of Pruritus in People on Hemodialysis. Clin J Am Soc Nephrol 2017 ; 12 (12) : 2000-7.
24) Gunal AI, Ozalp G, et al. Gabapentin therapy for pruritus in haemodialysis patients : a randomized, placebo-controlled, double-blind trial. Nephrol Dial Transplant 2004 ; 19 (12) : 3137-9.
25) Simonsen E, Komenda P, et al. Treatment of Uremic Pruritus : A Systematic Review. Am J Kidney Dis 2017 ; 70 (5) : 638-55.
26) Davison SN, Tupala B, et al. Recommendations for the Care of Patients Receiving Conservative Kidney Management : Focus on Management of CKD and Symptoms. Clin J Am Soc Nephrol 2019 ; 14 (4) : 626-34.
27) Cohen LM, Germain MJ, et al. Practical considerations in dialysis withdrawal : "to have that option is a blessing." JAMA 2003 ; 289 (16) : 2113-9.
28) O'Connor NR, Dougherty M, et al. Survival after dialysis discontinuation and hospice enrollment for ESRD. Clin J Am Soc Nephrol 2013 ; 8 (12) : 2117-22.
29) Cohen LM, Germain M, et al. Dialysis discontinuation and palliative care. Am J Kidney Dis 2000 ; 36 (1) : 140-4.
P.181 掲載の参考文献
1) Narayana A, Katz N, et al. National Breakthrough Pain Study : prevalence, characteristics, and associations with health outcomes. Pain. 2015 ; 156 : 252-59.
2) McPherson ML. Demystifying Opioid Conversion Calculations : A Guide for Effective Dosing (2nd edition). American Society of Health-System Pharmacists ; 2018.
3) McPherson ML. Demystifying Opioid Conversion Calculations : A Guide for Effective Dosing (1st edition). American Society of Health-System Pharmacists ; 2009.
4) "Weak" opioid analgesics. Codeine, dihydrocodeine and tramadol : no less risky than morphine. Prescrire Int. 2016 ; 25 : 45-50.
5) Juurlink D. Tramadont (https://toxandhound.com/toxhound/tramadont).
P.203 掲載の参考文献
1) Allan L, Hays H, Jensen NH, et al. Randomised crossover trial of transdermal fentanyl and sustained release oral morphine for treating chronic non-cancer pain. BMJ. 2001 ; 322 : 1154-8.
2) Woodward OB, Naraen S, et al. Opioid-induced myoclonus and hyperalgesia following a short course of low-dose oral morphine. Br J Pain. 2017 Feb ; 11 (1) : 32-5.
3) McPherson MLM. Demystifying Opioid Conversion Calculations : A Guide for Effective Dosing. American Society of Health-System Pharmacists ; 2018.
4) Reddy A, Tayjasanant S, et al. The opioid rotation ratio of strong opioids to transdermal fentanyl in cancer patients. Cancer. 2016 Jan 1 ; 122 (1) : 149-56.
5) Donner B, Zenz M, et al. Direct conversion from oral morphine to transdermal fentanyl : a multicenter study in patients with cancer pain. Pain. 1996 Mar ; 64 (3) : 527-34.
6) Reddy A, Yennurajalingam S, et al. The Opioid Rotation Ratio From Transdermal Fentanyl to "Strong" Opioids in Patients With Cancer Pain. J Pain Symptom Manage 2016 ; 51 (6) : 1040-5.
7) Donner B, Zenz M, et al. Long-Term Treatment of Cancer Pain With Transdermal Fentanyl. J Pain Symptom Manage. 1998 ; 15 : 168-75.
8) Bouhassira D, Attal N, et al. Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4). Pain. 2005 ; 114 : 29-36.
9) Krebs EE, Gravely A, et al. Effect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients with Chronic Back Pain or Hip or Knee Osteoarthritis Pain : The SPACE Randomized Clinical Trial. JAMA. 2018 ; 319 : 872-82.
10) 日本ペインクリニック学会非がん性慢性疼痛に対するオピオイド鎮痛薬処方ガイドライン作成ワーキンググループ (編). 非がん性慢性疼痛に対するオピオイド鎮痛薬処方ガイドライン 改訂第2版. 真興交易医書出版部, 2017.

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