1) Huang YP, Miescher PA, Zubler RH. The interleukin-2 secretion defect in vitro in systemic lupus erythematosus is reversible in rested cultured T cells. J Immunol 1986 ; 137 : 3515-20.
2) Amano K, Takeuchi T, Abe T, et al. Umbalanced tyrosine phosphorylation in signal transduction molecules in SLE T cells. Arthritis Rheum 1996 ; 39 : S118.
3) Irving BA, Weiss A. The cytoplasmic domain of the T cell receptor ζ chain is sufficient to couple to receptor-associated signal transduction pathways. Cell 1991 ; 64 : 891-901.
4) 竹内勤. SLEのT細胞シグナル伝達異常. 医学のあゆみ 1996 ; 176 : 335.
5) Takeuchi T, Tsuzaka K, Pang M, et al. TCRζ chain lacking exon 7 in two patients with systemic lupus erythematosus. Int Immunol 1998 ; 10 : 911-21.
6) Pang M, Setoyama Y, Tsuzaka K, et al. Defective expression and tyrosine phosphorylation of the T cell receptor ζ chain in peripheral blood T cells from systemic lupus erythematosus patients. Clin Exp Immunol 2002 ; 129 : 160-8.
7) Tsuzaka K, Takeuchi T, Onoda N, et al. Mutations in T cell receptor ζ chain mRNA of peripheral T cells from systemic lupus erythematosus. J Autoimmunity 1998 ; 11 : 381-5.
8) Tsuzaka K, Onoda N, Yoshimoto K, et al. T-cell receptor ζ mRNA with alternatively spliced 3' untranslated region is generated predominantly in the peripheral blood T cells of systemic lupus erythematosus patients. Mod Rheumatol 2002 ; 12 : 167-73.
9) Tsuzaka K, Fukuhara I, Setoyama Y, et al. TCRζ mRNA with an alternatively spliced 3' untranslated region detected in SLE patients leads to the downregulation of TCRζ and TCR/CD3 complex. J Immunol 2003 ; 171 : 2496-503.
10) Tsuzaka K, Setoyama Y, Yoshimoto K, et al. A splice variant of the TCR ζ mRNA lacking exon 7 leads to the down-regulation of TCR ζ, the TCR/CD3 complex, and IL-2 production in SLE T cells. J Immunol 2005 ; 174 : 3518-25.
11) Tsuzaka K, Itami Y, Kumazawa C, et al. Conservative sequences in 3' UTR of TCRζ mRNA regulate TCRζ in SLE T cells. Biochem Biophys Res Commun 2008 ; 367 : 311-7.